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21 results on '"Goel, Nikita"'

1. Subretinal hyporeflective globule: A novel OCT finding in central serous chorioretinopathy

Author

Goel, Sugandha, Mishra, Samarth, Bhattacharya, Sampurna, Majumdar, Bristi, Sen, Ahana, Mukherjee, Riya, Ramandhane, Raghul Nandan, Goel, Nikita, Saurabh, Kumar, and Roy, Rupak

Subjects
Choroid -- Physiological aspects -- Health aspects, Retinal diseases -- Diagnosis -- Care and treatment, Optical tomography -- Methods
Abstract

Purpose: To describe the subretinal hyporeflective globule in cases of central serous chorioretinopathy (CSC). Methods: A retrospective analysis of consecutive cases of CSC presenting to a tertiary eye care center in eastern India was conducted. Subretinal hyporeflective globules were identified as small globular lesions below the external limiting membrane/ellipsoid zone, but above the RPE layer. They had a hyperreflective border with a hyporeflective core and a clear posterior tail of hyper-transmission. Results: The present study analyzed 137 eyes of 137 patients. Eighty (58.4%) eyes had acute disease at presentation, 48 (35%) eyes had chronic disease, and eight (5.8%) eyes had resolved CSC. Subretinal hyporeflective globules were seen in 27 (21.8%) eyes, of which choroidal caverns were seen in seven (5.1%) eyes. Twenty-five eyes with chronic CSC and only two eyes with acute CSC had subretinal hyporeflective globules. Three eyes with resolved CSC had subretinal hyporeflective globules. Conclusion: We describe subretinal hyporeflective globule as a novel optical coherence tomography (OCT) finding in cases of CSC and describe its clinical correlates. Keywords: Central serous chorioretinopathy, choroidal caverns, subretinal hyporeflective globule, Author(s): Sugandha Goel [1]; Samarth Mishra [1]; Sampurna Bhattacharya [2]; Bristi Majumdar [2]; Ahana Sen [2]; Riya Mukherjee [2]; Raghul Nandan Ramandhane [2]; Nikita Goel [2]; Kumar Saurabh [1]; Rupak [...]

Published
2024
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2. Pupil vignetting artifact on optical coherence tomography angiography

Author

Bhattacharyya, Sampurna, D'Souza, Zubin, Ramanadhane, Raghulnadhan, Maitra, Debalina, Goel, Nikita, Sen, Ahana, Majumder, Bristi, Gupta, Shamayita, Chowdhury, Maitreyi, Chattree, Surabhi, Saurabh, Kumar, and Roy, Rupak

Subjects
Angiography, Tomography, Health
Abstract

Byline: Sampurna. Bhattacharyya, Zubin. D'souza, Raghulnadhan. Ramanadhane, Debalina. Maitra, Nikita. Goel, Ahana. Sen, Bristi. Majumder, Shamayita. Gupta, Maitreyi. Chowdhury, Surabhi. Chattree, Kumar. Saurabh, Rupak. Roy Purpose: To discuss the features [...]

Published
2024

3. Clinical feature of cystoid macular degeneration in central serous chorioretinopathy

Author

Gorhe, Sukanya, Chugh, Manpreet, Goel, Nikita, D'Souza, Zubin, Saurabh, Kumar, and Roy, Rupak

Subjects
Eye diseases -- Physiological aspects, Medical records -- Physiological aspects, Health
Abstract

Byline: Sukanya. Gorhe, Manpreet. Chugh, Nikita. Goel, Zubin. D'Souza, Kumar. Saurabh, Rupak. Roy Purpose: Cystoid macular degeneration (CMD) is a feature of chronic central serous chorioretinopathy (CSCR). Present study intended [...]

Published
2023

4. Bacillary layer detachment in a case of diabetic retinopathy

Author

D'Souza, Zubin, Majumdar, Bristi, Sen, Ahana, Goel, Nikita, Thounaojam, Sanatombi, Saurabh, Kumar, and Roy, Rupak

Subjects
Diabetic retinopathy, Health
Abstract

Byline: Zubin. D'Souza, Bristi. Majumdar, Ahana. Sen, Nikita. Goel, Sanatombi. Thounaojam, Kumar. Saurabh, Rupak. Roy Bacillary layer detachment (BLD) is a newly described optical coherence tomography (OCT) feature described in [...]

Published
2023

5. Multimodal imaging of desferoxamine retinopathy

Author

Sen, Ahana, Thounaojam, Sanatombi, Majumdar, Bristi, Eswaran, Bhuvaneshwaran, Goel, Nikita, D'Souza, Zubin, Saurabh, Kumar, and Roy, Rupak

Subjects
Health
Abstract

Byline: Ahana. Sen, Sanatombi. Thounaojam, Bristi. Majumdar, Bhuvaneshwaran. Eswaran, Nikita. Goel, Zubin. D'souza, Kumar. Saurabh, Rupak. Roy We are reporting a case of desferoxamine toxicity in a 10-year-old female who [...]

Published
2023

7. Retinitis pigmentosa with acute central serous chorioretinopathy with pachychoroid phenotype

Author

Goel, Nikita, Sen, Ahana, Chattree, Surabhi, Kumar, Saurabh, and Roy, Rupak

Subjects
Retinitis pigmentosa -- Case studies -- Diagnosis, Health
Abstract

Byline: Nikita. Goel, Ahana. Sen, Surabhi. Chattree, Saurabh. Kumar, Rupak. Roy We report a case of retinitis pigmentosa (RP) coexisting with acute central serous chorioretinopathy (CSCR) with pachychoroid phenotype. A [...]

Published
2023

8. Familial exudative vitreoretinopathy with retinitis pigmentosa: A rare association

Author

Bhattacharyya, Sampurna, Sen, Ahana, Majumdar, Bristi, Thounaojam, Sanatombi, Baliarsingh, Ankeeta, Goel, Nikita, D'Souza, Zubin, Saurabh, Kumar, and Roy, Rupak

Subjects
Genetic disorders -- Case studies -- Diagnosis, Retinal diseases -- Case studies -- Diagnosis, Health
Abstract

Byline: Sampurna. Bhattacharyya, Ahana. Sen, Bristi. Majumdar, Sanatombi. Thounaojam, Ankeeta. Baliarsingh, Nikita. Goel, Zubin. D'souza, Kumar. Saurabh, Rupak. Roy Familial exudative vitreoretinopathy (FEVR) is a rare inherited slowly progressive disorder [...]

Published
2023

9. Migration of dexamethasone implant (OZURDEX[R]) into the anterior chamber in a pseudophakic eye with an intact capsular bag

Author

Majumdar, Bristi, Sen, Ahana, Goel, Nikita, D'Souza, Zubin, Thounaojam, Sanatombi, Chattree, Surabhi, Bhargava, Mona, Shree, Jay, Saurabh, Kumar, and Roy, Rupak

Subjects
Vision disorders -- Case studies -- Causes of, Dexamethasone -- Case studies -- Dosage and administration, Anterior chamber (Eye) -- Case studies -- Health aspects, Health
Abstract

Byline: Bristi. Majumdar, Ahana. Sen, Nikita. Goel, Zubin. D'Souza, Sanatombi. Thounaojam, Surabhi. Chattree, Mona. Bhargava, Jay. Shree, Kumar. Saurabh, Rupak. Roy Ozurdex® (Allergan, Inc., Irvine, CA, USA) is an intravitreal [...]

Published
2023

10. Pupil vignetting artifact on optical coherence tomography angiography

Author

Bhattacharyya, Sampurna, primary, D'souza, Zubin, additional, Ramanadhane, Raghulnadhan, additional, Maitra, Debalina, additional, Goel, Nikita, additional, Sen, Ahana, additional, Majumder, Bristi, additional, Gupta, Shamayita, additional, Chowdhury, Maitreyi, additional, Chattree, Surabhi, additional, Saurabh, Kumar, additional, and Roy, Rupak, additional

Published
2023
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12. Multicolor imaging to detect slit breaks in posterior polar retinal detachment

Author

Dey, Amrita, Sen, Ahana, Goel, Nikita, Saurabh, Kumar, and Roy, Rupak

Subjects
Retinal detachment, Health
Abstract

Byline: Amrita. Dey, Ahana. Sen, Nikita. Goel, Kumar. Saurabh, Rupak. Roy A 43-year-old myopic male presented with sudden onset diminution of vision in the right eye. Fundus evaluation revealed posterior [...]

Published
2023

13. Multimodal imaging of Henle fiber layer hemorrhage in retinal artery macroaneurysm

Author

Sen, Ahana, Goel, Nikita, Tripathi, Abhishek, Dey, Amrita, Chattree, Surabhi, Saurabh, Kumar, and Roy, Rupak

Subjects
Hemorrhage, Health
Abstract

Byline: Ahana. Sen, Nikita. Goel, Abhishek. Tripathi, Amrita. Dey, Surabhi. Chattree, Kumar. Saurabh, Rupak. Roy We have described Henle fiber layer (HFL) hemorrhage[1],[2],[3] for the first time in a case [...]

Published
2023

14. A neoteric approach for treatment of persistent macular hole using human amniotic membrane

Author

Gorhe, Sukanya, Eswaran, Bhuvaneshwaran, Chattree, Surabhi, Goel, Nikita, D'Souza, Zubin, Saurabh, Kumar, and Roy, Rupak

Subjects
Amnion -- Health aspects, Amniotic sac -- Health aspects, Macular degeneration -- Diagnosis -- Risk factors, Health
Abstract

Byline: Sukanya. Gorhe, Bhuvaneshwaran. Eswaran, Surabhi. Chattree, Nikita. Goel, Zubin. D'souza, Kumar. Saurabh, Rupak. Roy Treatment of persistent macular holes is a challenge. Various techniques have been devised to reduce [...]

Published
2023

16. TCA cycle tailoring facilitates optimal growth of proton-pumping NADH dehydrogenase-dependent Escherichia coli

Author

Goel, Nikita, Srivastav, Stuti, Patel, Arjun, Shirsath, Akshay, Panda, Tushar Ranjan, Patra, Malay, Feist, Adam M., Anand, Amitesh, Goel, Nikita, Srivastav, Stuti, Patel, Arjun, Shirsath, Akshay, Panda, Tushar Ranjan, Patra, Malay, Feist, Adam M., and Anand, Amitesh

Abstract

The bacterial lifestyle is plastic, requiring transcriptional, translational, and metabolic tailoring for survival. These dynamic cellular processes are energy intensive; therefore, flexible energetics is requisite for adaptive plasticity. An intricate network of complementary and supplementary pathways exists in bacterial energy metabolism. There are two main entry points for electrons in the aerobic electron transport system, NADH dehydrogenase (NDH) and succinate dehydrogenase (SDH), receiving electrons from NADH and succinate, respectively. Aerobic bacterial phyla have a non-proton-pumping NADH dehydrogenase, which is often the primary dehydrogenase under aerobiosis. Here, we report adaptive changes supporting growth restoration in an Escherichia coli strain lacking the primary dehydrogenase. Growth optimization is achieved by reducing the activity of succinate dehydrogenase, and thus we demonstrate a physiological discord between proton-pumping NADH dehydrogenase and succinate dehydrogenase in supporting growth. Beyond the fundamental understanding of the bioenergetic network, identifying this compensatory feature provides impetus to rational antimicrobial combinations for targeting the non-proton-pumping dehydrogenase.

Published
2023

17. Unveiling endophthalmitis post COVID-19 - A case series

Author

Khatwani, Paras, Goel, Nikita, Trivedi, Kinjal, and Aggarwal, Somesh

Subjects
Epidemics -- Forecasts and trends -- India, Endophthalmitis -- Diagnosis -- Care and treatment -- Case studies, Market trend/market analysis, Health
Abstract

Byline: Paras. Khatwani, Nikita. Goel, Kinjal. Trivedi, Somesh. Aggarwal Since December 2019, coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, has become a global pandemic. There has been a resurgence in [...]

Published
2021

19. Concomitant paracentral acute middle maculopathy and acute macular neuroretinopathy in eyes post-blunt trauma.

Author

Goel, Nikita, D' Souza, Zubin, Tripathi, Abhishek, Dey, Amrita, Sen, Ahana, Majumdar, Bristi, Thounaojam, Sanatombi, Roy, Rupak, and Saurabh, Kumar

Subjects
*OCULAR injuries, *MACULAR degeneration, *OPTICAL coherence tomography, *BLUNT trauma, *DIABETIC retinopathy, *VISUAL acuity
Abstract

Purpose: To analyze the imaging characteristics and the clinical course of patients showing concomitant paracentral acute middle maculopathy (PAMM) and acute macular neuroretinopathy (AMN) post-blunt trauma. Methods: PAMM and AMN lesions post-blunt trauma diagnosed on enhanced depth imaging optical coherence tomography (EDI-OCT) were recruited for the study. Results: Thirteen eyes of 13 individuals with a history of blunt trauma were included in the study, of whom 11 (85%) were males. Mean age of the patients was 33.62 (range 16-67) years. Mean visual acuity at presentation and the last visit was 1.67 log of minimum angle of resolution (logMAR) and 0.82 logMAR, respectively. Mean interval between trauma and imaging was 5.08 (range 1-15) days. All patients had unilateral involvement, with the right eye being involved in 10 patients (77%). All patients had concomitant PAMM and AMN lesions. Conclusion: Presence of coincident PAMM and AMN suggests a common pathophysiologic etiology, but the description of concomitant PAMM and AMN in the setting of blunt trauma to eye is hitherto unreported. Identifying AMN in a setting of PAMM requires meticulous examination of the OCT and OCTA images. It can be a cause of suboptimal visual recovery in such eyes. [ABSTRACT FROM AUTHOR]

Published
2023
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