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99 results on '"Gerold Schmitt-Ulms"'

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1. The MEF2A transcription factor interactome in cardiomyocytes

2. Somatostatin slows Aβ plaque deposition in aged APP NL-F/NL-F mice by blocking Aβ aggregation

3. Advances in Recombinant Adeno-Associated Virus Vectors for Neurodegenerative Diseases

4. Aβ43 aggregates exhibit enhanced prion-like seeding activity in mice

5. Cardiac glycoside-mediated turnover of Na, K-ATPases as a rational approach to reducing cell surface levels of the cellular prion protein.

6. Loss of prion protein control of glucose metabolism promotes neurodegeneration in model of prion diseases.

7. Application of CRISPR genetic screens to investigate neurological diseases

8. Aggregation of Aβ40/42 chains in the presence of cyclic neuropeptides investigated by molecular dynamics simulations.

9. The cellular prion protein interacts with and promotes the activity of Na,K-ATPases.

10. Rapid Generation of Human Neuronal Cell Models Enabling Inducible Expression of Proteins-of-interest for Functional Studies

11. Prion-like propagation of β-amyloid aggregates in the absence of APP overexpression

12. The human brain somatostatin interactome: SST binds selectively to P-type family ATPases.

13. Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation

14. Somatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers

15. Time-course global proteome analyses reveal an inverse correlation between Aβ burden and immunoglobulin M levels in the APPNL-F mouse model of Alzheimer disease.

16. NCAM1 Polysialylation

17. Drug Repositioning for Alzheimer's Disease Based on Systematic 'omics' Data Mining.

18. Prion Protein Deficiency Causes Diverse Proteome Shifts in Cell Models That Escape Detection in Brain Tissue.

19. Proteome‐wide identification of mycobacterial pupylation targets

20. The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis.

21. The Evolutionary unZIPping of a Dimerization Motif—A Comparison of ZIP and PrP Architectures

22. CRISPR-Cas9-based knockout of the prion protein and its effect on the proteome.

23. The ZIP5 ectodomain co-localizes with PrP and may acquire a PrP-like fold that assembles into a dimer.

24. PrionHome: a database of prions and other sequences relevant to prion phenomena.

25. Down-regulation of Shadoo in prion infections traces a pre-clinical event inversely related to PrP(Sc) accumulation.

26. Evidence for retrogene origins of the prion gene family.

27. Interactome analyses identify ties of PrP and its mammalian paralogs to oligomannosidic N-glycans and endoplasmic reticulum-derived chaperones.

29. Evolutionary descent of prion genes from the ZIP family of metal ion transporters.

30. The <scp>IDIP</scp> framework for assessing protein function and its application to the prion protein

31. Identification of a Cardiac Glycoside Exhibiting Favorable Brain Bioavailability and Potency for Reducing Levels of the Cellular Prion Protein

32. Aβ43 aggregates exhibit enhanced prion-like seeding activity in mice

33. The aminoglycoside G418 hinders de novo prion infection in cultured cells

34. An endogenous PI3K interactome promoting astrocyte-mediated neuroprotection identifies a novel association with RNA-binding protein ZC3H14

35. Rapid Generation of Human Neuronal Cell Models Enabling Inducible Expression of Proteins-of-interest for Functional Studies

36. The prion protein is embedded in a molecular environment that modulates transforming growth factor β and integrin signaling

37. Prion-like propagation of β-amyloid aggregates in the absence of APP overexpression

38. Somatostatin in Alzheimer's disease: A new Role for an Old Player

39. Application of CRISPR genetic screens to investigate neurological diseases

40. Tau interactome analyses in CRISPR-Cas9 engineered neuronal cells reveal ATPase-dependent binding of wild-type but not P301L Tau to non-muscle myosins

41. The human brain somatostatin interactome: SST binds selectively to P-type family ATPases

42. CRISPR-Cas9 System: Opportunities and Concerns

43. DoesBDNFVal66Met contribute to preclinical Alzheimer’s disease?

44. Bcl-2-associated athanogene 5 (BAG5) regulates Parkin-dependent mitophagy and cell death

45. The Human Tau Interactome: Binding to the Ribonucleoproteome, and Impaired Binding of the Proline-to-Leucine Mutant at Position 301 (P301L) to Chaperones and the Proteasome

46. Current and future implications of basic and translational research on amyloid-β peptide production and removal pathways

47. Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation

49. Somatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers

50. Time-course global proteome analyses reveal an inverse correlation between Aβ burden and immunoglobulin M levels in the APPNL-F mouse model of Alzheimer disease

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