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1. In Defense of Our Patients: Indirect Negative Neurological Consequences of SARS-CoV-2 in the New York Epicenter

Author

Cooper, Jared B, Amin, Anubhav G, Kim, Michael G, Stein, Alan A, Dominguez, Jose, Amuluru, Krishna, Tyagi, Rachana, Mayer, Stephan, Gandhi, Chirag D, and Al-Mufti, Fawaz

Subjects
Biomedical and Clinical Sciences, Neurosciences, Clinical Sciences, Good Health and Well Being, Adult, Aged, Betacoronavirus, COVID-19, Cerebrovascular Disorders, Coronavirus Infections, Delivery of Health Care, Integrated, Disease Progression, Emergencies, Female, Health Services Needs and Demand, Host-Pathogen Interactions, Humans, Male, Middle Aged, New York City, Pandemics, Patient Acceptance of Health Care, Patient Safety, Pneumonia, Viral, Risk Assessment, Risk Factors, SARS-CoV-2, Time Factors, Time-to-Treatment, Coronavirus, CoViD-19, Neurology & Neurosurgery, Clinical sciences
Published
2020

4. Gender Differences in Operative Autonomy Using the Surgical Autonomy Program: A Multicenter Study.

Author

Kirsch, Elayna P., Venkatraman, Vishal, Deng, Di, McDaniel, Katherine E., Suarez, Alexander D., Lew, Sean M., Orina, Josiah, Silberstein, Howard, Goldstein, Ira, Gould, Grahame, Gandhi, Chirag D., Patil, Chirag, Dengler, Bradley A., Dharmapurikar, Rajeev, Lad, Shivanand P., and Haglund, Michael M.

Subjects
ZONE of proximal development, TEACHING guides, GENDER inequality, SELF-evaluation, RESIDENTS (Medicine)
Abstract

Background The proportion of women surgeons is increasing, but studies show that women in surgical residency are granted less autonomy than men. Objective We utilized the Surgical Autonomy Program (SAP), an educational framework, to evaluate gender differences in self-reported autonomy, attending-reported autonomy, and operative feedback among US neurosurgical residents. Methods The SAP tracks resident progression and guides teaching in neurosurgery. Surgeries are divided into zones of proximal development (opening, exposure, critical portion, and closure). Postoperatively, resident autonomy is rated on a 4-point scale by the resident and the attending for each part of the case, or zone. We utilized data from July 2017 to February 2024 from 8 institutions. Ordinal regression was used to evaluate the odds of self- and attending-evaluated autonomy, accounting for gender, training year, case difficulty, and institution. Differences between attending assessment and self-assessment were calculated across time. Chi-square analyses were used to measure any differences in feedback given to men and women. Results From 128 residents (32 women, 25%), 11894 cases were included. Women were granted less autonomy (OR 0.81; 95% CI 0.74-0.89; P<.001) and self-evaluated as having less autonomy (OR 0.73; 95% CI 0.67-0.80; P<.001). The odds of women operating at higher autonomy were similar to the odds of operating on a hard case compared to average difficulty (OR 0.77; 95% CI 0.71-0.84; P<.001). Men's and women's self-assessment became closer to attending assessment over time, with women improving more quickly for the critical portions of surgeries. Women residents received meaningful postoperative feedback on fewer cases (women: 74.2%, men: 80.5%; X2=31.929; P<.001). Conclusions Women operated with lower autonomy by both attending and self-assessment, but the assessment gap between genders decreased over time. Women also received less feedback from their attendings. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Effect of chronic antiplatelet therapy on clinical outcomes of endovascular thrombectomy for treatment of acute ischemic stroke

Author

Dicpinigaitis, Alis J., primary, Chowdhury, Adeeb, additional, Gagliardi, Thomas A., additional, Soliman, Zeina, additional, Mahmoud, Noor A., additional, Nolan, Bridget, additional, Clare, Kevin, additional, Willey, Joshua Z., additional, Rostanski, Sara K., additional, Medicherla, Chaitanya, additional, Patel, Neisha, additional, Kaur, Gurmeen, additional, Chong, Ji Y., additional, Bowers, Christian A., additional, Gandhi, Chirag D., additional, and Al-Mufti, Fawaz, additional

Published
2023
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12. Ruptured arteriovenous malformation mortality: Incidence, risk factors, and inpatient outcome score

Author

Feldstein, Eric, primary, Zhong, Allison, additional, Clare, Kevin, additional, Nolan, Bridget, additional, Patel, Smit, additional, Lavi-Romer, Nir, additional, Stadlan, Zehavya, additional, Dicpinigaitis, Alis, additional, Dominguez, Jose, additional, Kamal, Haris, additional, Shapiro, Steven D., additional, Biswas, Arundhati, additional, Tanweer, Omar, additional, Bulsara, Ketan, additional, Muh, Carrie, additional, Pisapia, Jared, additional, Hanft, Simon, additional, Mayer, Stephan, additional, Gandhi, Chirag D., additional, and Al-Mufti, Fawaz, additional

Published
2023
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14. Acute ischemic strokes in patients with developmental disabilities: A cross-sectional analysis.

Author

Lui, Aiden, Feldstein, Eric, Clare, Kevin, Dicpinigaitis, Alis J, Reddy, Medha, Khan, Farzana, Semaan, Rosa, Galluzzo, Daniela, Shapiro, Steve, Kamal, Haris, Yaghi, Shadi, Pisapia, Jared, Muh, Carrie, Nuoman, Rolla, Overby, Philip, Etienne, Mill, Chong, Ji, Mayer, Stephan, Gandhi, Chirag D, and Al-Mufti, Fawaz

Subjects
STROKE patients, DEVELOPMENTAL disabilities, TISSUE plasminogen activator, CHILDREN with developmental disabilities, CROSS-sectional method, ISCHEMIC stroke, APHASIC persons
Abstract

Objective: Patients with developmental disabilities (DD) are frequently excluded from acute ischemic stroke (AIS) randomized control trials. We sought to evaluate the impact of having DD on this patient cohort Methods: The National Inpatient Sample was analyzed to explore the impact of AIS and treatment on discharge dispositions in patients with DD. Clinical characteristics, treatments, and outcomes were compared to fully-abled patients with AIS. Results: 1,605,723 patients with AIS were identified from 2010–2019, of whom 4094 (0.30%) had a DD. AIS patients with DD were younger (60.31 vs 70.93 years, p < 0.01), less likely to be Caucasian (66.37%vs 68.09%, p = 0.01), and had higher AIS severity (0.63 vs 0.58, p < 0.01). Tissue plasminogen activator (tPA) was administered in 99,739 (6.2%) fully-abled patients and 196 (4.79%) of patients with DD (p < 0.01). Endovascular thrombectomy (EVT) was performed in 21,066 (1.31%) of fully-abled patients and 35 (0.85%) of patients with DD (p < 0.01). The presence of developmental disabilities were predictive of lower rates of tPA (OR:0.71,CI:0.56–0.87,p < 0.01) and EVT (OR:0.24,CI:0.16–0.36,p < 0.01). In a propensity score-matched cohort of all AIS patients who underwent EVT, there was no difference in functional outcome (p = 0.41), in-hospital mortality (0.10), and LOS (p = 0.79). Conclusion: AIS patients with DD were less likely to receive tPA and EVT compared to fully-abled patients. Individuals with DD had higher mortality and worse discharge disposition. There was no significant difference in post-EVT outcomes between fully-abled patients and patients with developmental disabilities. In the absence of prospective clinical trials, population based cross-sectional analyses such as the present study provide valuable clinical insight. [ABSTRACT FROM AUTHOR]

Published
2023
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17. sj-docx-1-ine-10.1177_15910199231173458 - Supplemental material for Ruptured arteriovenous malformation mortality: Incidence, risk factors, and inpatient outcome score

Author

Feldstein, Eric, Zhong, Allison, Clare, Kevin, Nolan, Bridget, Patel, Smit, Lavi-Romer, Nir, Stadlan, Zehavya, Dicpinigaitis, Alis, Dominguez, Jose, Kamal, Haris, Shapiro, Steven D., Biswas, Arundhati, Tanweer, Omar, Bulsara, Ketan, Muh, Carrie, Pisapia, Jared, Hanft, Simon, Mayer, Stephan, Gandhi, Chirag D., and Al-Mufti, Fawaz

Subjects
FOS: Clinical medicine, 110904 Neurology and Neuromuscular Diseases, Neuroscience
Abstract

Supplemental material, sj-docx-1-ine-10.1177_15910199231173458 for Ruptured arteriovenous malformation mortality: Incidence, risk factors, and inpatient outcome score by Eric Feldstein, Allison Zhong, Kevin Clare, Bridget Nolan, Smit Patel, Nir Lavi-Romer, Zehavya Stadlan, Alis Dicpinigaitis, Jose Dominguez, Haris Kamal, Steven D. Shapiro, Arundhati Biswas, Omar Tanweer, Ketan Bulsara, Carrie Muh, Jared Pisapia, Simon Hanft, Stephan Mayer, Chirag D. Gandhi and Fawaz Al-Mufti in Interventional Neuroradiology

Published
2023
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18. sj-docx-3-ine-10.1177_15910199231170679 - Supplemental material for The gut-brain connection: Inflammatory bowel disease increases risk of acute ischemic stroke

Author

Mui, Nicholas W, Uddin, Anaz, Fortunato, Michael P, Nolan, Bridget E, Clare, Kevin M, Lui, Aiden K, Al-Juboori, Mohammed, Gandhi, Chirag D, and Al-Mufti, Fawaz

Subjects
FOS: Clinical medicine, 110904 Neurology and Neuromuscular Diseases, Neuroscience
Abstract

Supplemental material, sj-docx-3-ine-10.1177_15910199231170679 for The gut-brain connection: Inflammatory bowel disease increases risk of acute ischemic stroke by Nicholas W Mui, Anaz Uddin, Michael P Fortunato, Bridget E Nolan, Kevin M Clare, Aiden K Lui, Mohammed Al-Juboori, Chirag D Gandhi and Fawaz Al-Mufti in Interventional Neuroradiology

Published
2023
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19. sj-docx-1-ine-10.1177_15910199231170679 - Supplemental material for The gut-brain connection: Inflammatory bowel disease increases risk of acute ischemic stroke

Author

Mui, Nicholas W, Uddin, Anaz, Fortunato, Michael P, Nolan, Bridget E, Clare, Kevin M, Lui, Aiden K, Al-Juboori, Mohammed, Gandhi, Chirag D, and Al-Mufti, Fawaz

Subjects
FOS: Clinical medicine, 110904 Neurology and Neuromuscular Diseases, Neuroscience
Abstract

Supplemental material, sj-docx-1-ine-10.1177_15910199231170679 for The gut-brain connection: Inflammatory bowel disease increases risk of acute ischemic stroke by Nicholas W Mui, Anaz Uddin, Michael P Fortunato, Bridget E Nolan, Kevin M Clare, Aiden K Lui, Mohammed Al-Juboori, Chirag D Gandhi and Fawaz Al-Mufti in Interventional Neuroradiology

Published
2023
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20. sj-docx-2-ine-10.1177_15910199231170679 - Supplemental material for The gut-brain connection: Inflammatory bowel disease increases risk of acute ischemic stroke

Author

Mui, Nicholas W, Uddin, Anaz, Fortunato, Michael P, Nolan, Bridget E, Clare, Kevin M, Lui, Aiden K, Al-Juboori, Mohammed, Gandhi, Chirag D, and Al-Mufti, Fawaz

Subjects
FOS: Clinical medicine, 110904 Neurology and Neuromuscular Diseases, Neuroscience
Abstract

Supplemental material, sj-docx-2-ine-10.1177_15910199231170679 for The gut-brain connection: Inflammatory bowel disease increases risk of acute ischemic stroke by Nicholas W Mui, Anaz Uddin, Michael P Fortunato, Bridget E Nolan, Kevin M Clare, Aiden K Lui, Mohammed Al-Juboori, Chirag D Gandhi and Fawaz Al-Mufti in Interventional Neuroradiology

Published
2023
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21. An institutional report of heparin induced thrombocytopenia type II in aneurysmal subarachnoid hemorrhage patients.

Author

Li, Boyi, Sursal, Tolga, Martinez, Erick, Karimov, Zafar, Feldstein, Eric, Stein, Alan, Cooper, Jared, Hosein-Woodley, Rasheed, Liu, Aiden, McIntyre, Matthew, Bowers, Christian, Hanft, Simon, Hafeez, Zeeshan, Pisapia, Jared, Muh, Carrie, Tyagi, Rachana, Mayer, Stephan A., Gandhi, Chirag D., and Al-Mufti, Fawaz

Subjects
SUBARACHNOID hemorrhage, DIGITAL subtraction angiography, CEREBRAL vasospasm, HEPARIN, ACADEMIC medical centers, THROMBOCYTOPENIA
Abstract

Background: Heparin induced thrombocytopenia Type II (HIT-II) is a dangerous thromboembolic complication of heparin therapy. The current literature on incidence and outcomes of HIT-II in aneurysmal subarachnoid hemorrhage (aSAH) patients remains sparse. Objective: We report our institution's incidence and outcomes of HIT-II in aSAH patients. Methods: We performed a retrospective cohort study at an academic medical center between June 2014 and July 2018. All patients had aSAH confirmed by digital subtraction angiography. Diagnosis of HIT-II was determined by positive results on both heparin PF4-platelet antibody ELISA (anti-PF4) and serotonin release assay (SRA). Results: 204 patients met inclusion criteria. Seven patients (7/204, 3.5%) underwent laboratory testing, three of whom met clinical criteria. HIT-II incidence was confirmed in two of these seven patients (2/204, 0.98%), who had high BMI and T4 scores. Conclusion: Our institution's report of HIT-II incidence in aSAH patients is lower than previously reported in this population and more closely parallels HIT-II incidence in the general and surgical ICU setting. Widely-accepted American College of Chest Physicians (ACCP) clinical diagnostic criteria in conjunction with anti-PF4 and SRA testing is the gold standard of clinical diagnosis of HIT-II in aSAH patients. [ABSTRACT FROM AUTHOR]

Published
2023
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23. Acute ischemic strokes in patients with developmental disabilities: A cross-sectional analysis

Author

Lui, Aiden, primary, Feldstein, Eric, additional, Clare, Kevin, additional, Dicpinigaitis, Alis J, additional, Reddy, Medha, additional, Khan, Farzana, additional, Semaan, Rosa, additional, Galluzzo, Daniela, additional, Shapiro, Steve, additional, Kamal, Haris, additional, Yaghi, Shadi, additional, Pisapia, Jared, additional, Muh, Carrie, additional, Nuoman, Rolla, additional, Overby, Philip, additional, Etienne, Mill, additional, Chong, Ji, additional, Mayer, Stephan, additional, Gandhi, Chirag D, additional, and Al-Mufti, Fawaz, additional

Published
2022
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24. Cerebral vasospasm following arteriovenous malformation rupture: a population-based cross-sectional study

Author

Dicpinigaitis, Alis J., primary, Feldstein, Eric, additional, Shapiro, Steven D., additional, Kamal, Haris, additional, Bauerschmidt, Andrew, additional, Rosenberg, Jon, additional, Amuluru, Krishna, additional, Pisapia, Jared, additional, Dangayach, Neha S., additional, Liang, John W., additional, Bowers, Christian A., additional, Mayer, Stephan A., additional, Gandhi, Chirag D., additional, and Al-Mufti, Fawaz, additional

Published
2022
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27. Acute Respiratory Distress Syndrome in Patients with Subarachnoid Hemorrhage: Incidence, Predictive Factors, and Impact on Mortality.

Author

Feldstein, Eric, Ali, Syed, Patel, Smit, Raghavendran, Keshav, Martinez, Erick, Blowes, Leah, Ogulnick, Jonathan, Bravo, Michelle, Dominguez, Jose, Li, Boyi, Urhie, Ogaga, Rosenberg, Jon, Bowers, Christian, Prabhakaran, Kartik, Bauershmidt, Andrew, Mayer, Stephan A., Gandhi, Chirag D., and Al-Mufti, Fawaz

Subjects
ADULT respiratory distress syndrome, SUBARACHNOID hemorrhage, CEREBRAL vasospasm, CEREBRAL edema, CARDIOGENIC shock
Abstract

Introduction: Acute respiratory distress syndrome (ARDS) is a known predictor of poor outcomes in critically ill patients. We sought to examine the role ARDS plays in outcomes in subarachnoid hemorrhage (SAH) patients. Prior studies investigating the incidence of ARDS in SAH patients did not control for SAH severity. Hence, we sought to determine the incidence ARDS in patients diagnosed with aneurysmal SAH and investigate the predisposing risk factors and impact upon outcomes. Methods: A retrospective cohort study was conducted using the National Inpatient Sample (NIS) database for the years 2008 to 2014. Multivariate stepwise regression analysis was performed to identify the risk factors and outcome associated with developing ARDS in the setting of SAH. Results: We identified 170,869 patients with non-traumatic subarachnoid hemorrhage, of whom 6962 were diagnosed with ARDS and of those 4829 required mechanical ventilation. ARDS more frequently developed in high grade SAH patients (1.97 ± 0.05 vs. 1.15 ± 0.01; p < 0.0001). Neurologic predictors of ARDS included cerebral edema (OR 1.892, CI 1.180–3.034, p = 0.0035) and medical predictors included cardiac arrest (OR 4.642, CI 2.273–9.482, p < 0.0001) and cardiogenic shock (OR 2.984, CI 1.157–7.696, p = 0.0239). ARDS was associated with significantly worse outcomes (15.5% vs. 52.9% discharged home, 63.0% vs. 40.8% discharged to rehabilitation facility and 21.5% vs. 6.3% in-hospital mortality). Conclusion: Patients with SAH who developed ARDS were less likely to be discharged home, more likely to need rehabilitation and had a significantly higher risk of mortality. The identification of risk factors contributing to ARDS is helpful for improving outcomes and resource utilization. [ABSTRACT FROM AUTHOR]

Published
2023
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28. Endovascular Thrombectomy for Pediatric Acute Ischemic Stroke

Author

Dicpinigaitis, Alis J., primary, Gandhi, Chirag D., additional, Pisapia, Jared, additional, Muh, Carrie R., additional, Cooper, Jared B., additional, Tobias, Michael, additional, Mohan, Avinash, additional, Nuoman, Rolla, additional, Overby, Philip, additional, Santarelli, Justin, additional, Hanft, Simon, additional, Bowers, Christian, additional, Yaghi, Shadi, additional, Mayer, Stephan A., additional, and Al-Mufti, Fawaz, additional

Published
2022
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29. Neutrophil–Lymphocyte ratio is associated with poor clinical outcome after mechanical thrombectomy in stroke in patients with COVID-19

Author

Al-Mufti, Fawaz, primary, Khandelwal, Priyank, additional, Sursal, Tolga, additional, Cooper, Jared B., additional, Feldstein, Eric, additional, Amuluru, Krishna, additional, Moré, Jayaji M., additional, Tiwari, Ambooj, additional, Singla, Amit, additional, Dmytriw, Adam A, additional, Piano, Mariangela, additional, Quilici, Luca, additional, Pero, Guglielmo, additional, Renieri, Leonardo, additional, Limbucci, Nicola, additional, Martínez-Galdámez, Mario, additional, Schüller-Arteaga, Miguel, additional, Galván, Jorge, additional, Arenillas-Lara, Juan Francisco, additional, Hashim, Zafar, additional, Nayak, Sanjeev, additional, Desousa, Keith, additional, Sun, Hai, additional, Agarwalla, Pankaj K., additional, Sudipta Roychowdhury, J, additional, Nourollahzadeh, Emad, additional, Prakash, Tannavi, additional, Xavier, Andrew R, additional, Diego Lozano, J, additional, Gupta, Gaurav, additional, Yavagal, Dileep R, additional, Elghanem, Mohammad, additional, Gandhi, Chirag D., additional, and Mayer, Stephan A., additional

Published
2022
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30. An institutional report of heparin induced thrombocytopenia type II in aneurysmal subarachnoid hemorrhage patients

Author

Li, Boyi, primary, Sursal, Tolga, additional, Martinez, Erick, additional, Karimov, Zafar, additional, Feldstein, Eric, additional, Stein, Alan, additional, Cooper, Jared, additional, Hosein-Woodley, Rasheed, additional, Liu, Aiden, additional, McIntyre, Matthew, additional, Bowers, Christian, additional, Hanft, Simon, additional, Hafeez, Zeeshan, additional, Pisapia, Jared, additional, Muh, Carrie, additional, Tyagi, Rachana, additional, Mayer, Stephan A., additional, Gandhi, Chirag D., additional, and Al-Mufti, Fawaz, additional

Published
2022
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31. Acute Respiratory Distress Syndrome in Patients with Subarachnoid Hemorrhage: Incidence, Predictive Factors, and Impact on Mortality

Author

Feldstein, Eric, primary, Ali, Syed, additional, Patel, Smit, additional, Raghavendran, Keshav, additional, Martinez, Erick, additional, Blowes, Leah, additional, Ogulnick, Jonathan, additional, Bravo, Michelle, additional, Dominguez, Jose, additional, Li, Boyi, additional, Urhie, Ogaga, additional, Rosenberg, Jon, additional, Bowers, Christian, additional, Prabhakaran, Kartik, additional, Bauershmidt, Andrew, additional, Mayer, Stephan A., additional, Gandhi, Chirag D., additional, and Al-Mufti, Fawaz, additional

Published
2022
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32. Development of cerebral vasospasm following traumatic intracranial hemorrhage: incidence, risk factors, and clinical outcomes

Author

Dicpinigaitis, Alis J., primary, Feldstein, Eric, additional, Damodara, Nitesh, additional, Cooper, Jared B., additional, Shapiro, Steven D., additional, Kamal, Haris, additional, Kinon, Merritt D., additional, Pisapia, Jared, additional, Rosenberg, Jon, additional, Gandhi, Chirag D., additional, and Al-Mufti, Fawaz, additional

Published
2022
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33. Cardiac arrest in spontaneous subarachnoid hemorrhage and associated outcomes

Author

Feldstein, Eric, primary, Dominguez, Jose F., additional, Kaur, Gurkamal, additional, Patel, Smit D., additional, Dicpinigaitis, Alis J., additional, Semaan, Rosa, additional, Fuentes, Leanne E., additional, Ogulnick, Jonathan, additional, Ng, Christina, additional, Rawanduzy, Cameron, additional, Kamal, Haris, additional, Pisapia, Jared, additional, Hanft, Simon, additional, Amuluru, Krishna, additional, Naidu, Srihari S., additional, Cooper, Howard A., additional, Prabhakaran, Kartik, additional, Mayer, Stephan A., additional, Gandhi, Chirag D., additional, and Al-Mufti, Fawaz, additional

Published
2022
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34. sj-docx-1-ine-10.1177_15910199221110327 - Supplemental material for Acute ischemic strokes in patients with developmental disabilities: A cross-sectional analysis

Author

Lui, Aiden, Feldstein, Eric, Clare, Kevin, Dicpinigaitis, Alis J, Reddy, Medha, Khan, Farzana, Semaan, Rosa, Galluzzo, Daniela, Shapiro, Steve, Kamal, Haris, Yaghi, Shadi, Pisapia, Jared, Muh, Carrie, Nuoman, Rolla, Overby, Philip, Etienne, Mill, Chong, Ji, Mayer, Stephan, Gandhi, Chirag D, and Al-Mufti, Fawaz

Subjects
FOS: Clinical medicine, 110904 Neurology and Neuromuscular Diseases, Neuroscience
Abstract

Supplemental material, sj-docx-1-ine-10.1177_15910199221110327 for Acute ischemic strokes in patients with developmental disabilities: A cross-sectional analysis by Aiden Lui, Eric Feldstein, Kevin Clare, Alis J Dicpinigaitis, Medha Reddy, Farzana Khan, Rosa Semaan, Daniela Galluzzo, Steve Shapiro, Haris Kamal, Shadi Yaghi, Jared Pisapia, Carrie Muh, Rolla Nuoman, Philip Overby, Mill Etienne, Ji Chong, Stephan Mayer, Chirag D Gandhi and Fawaz Al-Mufti in Interventional Neuroradiology

Published
2022
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35. Impact of Endoluminal Flow Diverter Number on Aneurysm Treatment Outcomes: A Multicenter Study

Author

Vranic, Justin E., primary, Harker, Pablo, additional, Stapleton, Christopher J., additional, Regenhardt, Robert W., additional, Alotaibi, Naif M., additional, Leslie‐Mazwi, Thabele M., additional, Gupta, Rajiv, additional, Tan, Can Ozan, additional, Koch, Matthew J., additional, Dmytriw, Adam A., additional, Raymond, Scott B., additional, Mascitelli, Justin R., additional, Patterson, T. Tyler, additional, Seinfeld, Joshua, additional, White, Andrew, additional, Case, David, additional, Roark, Christopher, additional, Gandhi, Chirag D., additional, Al‐Mufti, Fawaz, additional, Cooper, Jared, additional, Matouk, Charles, additional, Sujijantarat, Nanthiya, additional, Devia, Diego A., additional, Ocampo‐Navia, Maria I., additional, Villamizar‐Torres, Daniel E., additional, Puentes, Juan C., additional, and Patel, Aman B., additional

Published
2022
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36. Utility of frailty as a predictor of acute kidney injury in patients with aneurysmal subarachnoid hemorrhage

Author

Ng, Christina, primary, Dominguez, Jose F, additional, Hosein-Woodley, Rasheed, additional, Feldstein, Eric, additional, Naftchi, Alexandria, additional, Lui, Aiden, additional, Dicpinigaitis, Alis J, additional, McIntyre, Matthew K, additional, Kaur, Gurmeen, additional, Santarelli, Justin, additional, Bauerschmidt, Andrew, additional, Mayer, Stephan A, additional, Bowers, Christian A, additional, Gandhi, Chirag D, additional, and Al-Mufti, Fawaz, additional

Published
2022
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37. Abstract WP11: The Impact Of Dual Antiplatelet Therapy Duration On Unruptured Aneurysm Occlusion Following Flow Diversion

Author

Vranic, Justin, primary, Harker, Pablo, additional, Stapleton, Christopher, additional, Regenhardt, Robert W, additional, Alotaibi, Naif, additional, Leslie-mazwi, Thabele M, additional, Gupta, Rajiv, additional, Tan, Can Ozan, additional, Koch, Matthew J, additional, Dmytriw, Adam A, additional, Raymond, Scott B, additional, Mascitelli, Justin, additional, Patterson, Tyler, additional, Seinfeld, Joshua, additional, White, Andrew, additional, Case, David, additional, Roark, Christopher, additional, Gandhi, Chirag D, additional, Al-Mufti, Fawaz, additional, Cooper, Jared, additional, Matouk, Charles, additional, Sujijantarat, Nanthiya, additional, Devia, Diego A, additional, Villamizar-Torres, Daniel E, additional, Ocampo-Navia, Maria A, additional, Puentes, Juan C, additional, and Patel, Aman B, additional

Published
2022
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38. Incidence and Risk Factors for Acute Transient Contrast‐Induced Neurologic Deficit: A Systematic Review With Meta‐Analysis

Author

Vazquez, Sima, primary, Graifman, Gillian, additional, Spirollari, Eris, additional, Ng, Christina, additional, Uddin, Anaz, additional, Feldstein, Eric, additional, Naftchi, Alexandria, additional, Dominguez, Jose F, additional, Lui, Aiden, additional, Mayer, Stephan A, additional, Santarelli, Justin, additional, Kaur, Gurmeen, additional, Bauerschmidt, Andrew, additional, Gandhi, Chirag D, additional, and Al‐Mufti, Fawaz, additional

Published
2022
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40. Utility of frailty as a predictor of acute kidney injury in patients with aneurysmal subarachnoid hemorrhage.

Author

Ng, Christina, Dominguez, Jose F, Hosein-Woodley, Rasheed, Feldstein, Eric, Naftchi, Alexandria, Lui, Aiden, Dicpinigaitis, Alis J, McIntyre, Matthew K, Kaur, Gurmeen, Santarelli, Justin, Bauerschmidt, Andrew, Mayer, Stephan A, Bowers, Christian A, Gandhi, Chirag D, and Al-Mufti, Fawaz

Subjects
ACUTE kidney failure, SUBARACHNOID hemorrhage, CEREBRAL vasospasm, FRAILTY, DEMOGRAPHIC characteristics, DATABASES
Abstract

Introduction: Acute kidney injury (AKI) is associated with poor outcome in aneurysmal subarachnoid hemorrhage patients (aSAH). Frailty has recently been demonstrated to correlate with elevated mortality and morbidity; its impact on predicting AKI and mortality in aSAH patients has not been investigated. Objective: Evaluating risk factors and predictors for AKI in aSAH patients. Methods: aSAH patients from a single-center's prospectively maintained database were retrospectively evaluated for development of AKI within 14 days of admission. Baseline demographic and clinical characteristics were collected. The effect of frailty and other risk factors were evaluated. Results: Of 213 aSAH patients, 53 (33.1%) were frail and 12 (5.6%) developed AKI. Admission serum creatinine (sCr) and peak sCr within 48 h were higher in frail patients. AKI patients showed a trend towards higher frailty. Mortality was significantly higher in AKI than non-AKI aSAH patients. Frailty was a poor predictor of AKI when controlling for Hunt and Hess (HH) grade or age. HH grade ≥ 4 strongly predicted AKI when controlling for frailty. Conclusion: AKI in aSAH patients carries a poor prognosis. The HH grade appears to have superior utility as a predictor of AKI in aSAH patients than mFI. [ABSTRACT FROM AUTHOR]

Published
2023
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41. Determinants of intracranial aneurysm retreatment following embolization with a single flow-diverting stent

Author

Vranic, Justin E, primary, Harker, Pablo, additional, Stapleton, Christopher J, additional, Regenhardt, Robert W, additional, Dmytriw, Adam A, additional, Alotaibi, Naif M, additional, Gupta, Rajiv, additional, Leslie-Mazwi, Thabele M, additional, Koch, Matthew J, additional, Raymond, Scott B, additional, Mascitelli, Justin R, additional, Patterson, T Tyler, additional, Seinfeld, Joshua, additional, White, Andrew, additional, Case, David, additional, Roark, Christopher, additional, Gandhi, Chirag D, additional, Al-Mufti, Fawaz, additional, Cooper, Jared, additional, and Patel, Aman B, additional

Published
2021
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42. Abstract 1122‐000059: Considering Transcarotid Access for Mechanical Thrombectomy in Acute Ischemic Stroke: A Meta‐Analysis and Systematic Review

Author

Zhong, Allison J, primary, Zhong, Allison J, additional, Kamal, Haris, additional, Uddin, Anaz, additional, Feldstein, Eric, additional, Shapiro, Steven D, additional, Chung, Joon Yong, additional, Ogarro, Maziyah, additional, Friedman, Rebecca, additional, Simmons, Josh, additional, Graifman, Gillian, additional, Kurian, Christeena, additional, Kaur, Gurmeen, additional, Mayer, Stephan A, additional, Chong, Ji, additional, Gandhi, Chirag D, additional, and Al‐Mufti, Fawaz, additional

Published
2021
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45. Determinants of intracranial aneurysm retreatment following embolization with a single flow-diverting stent.

Author

Vranic, Justin E, Harker, Pablo, Stapleton, Christopher J, Regenhardt, Robert W, Dmytriw, Adam A, Alotaibi, Naif M, Gupta, Rajiv, Leslie-Mazwi, Thabele M, Koch, Matthew J, Raymond, Scott B, Mascitelli, Justin R, Patterson, T Tyler, Seinfeld, Joshua, White, Andrew, Case, David, Roark, Christopher, Gandhi, Chirag D, Al-Mufti, Fawaz, Cooper, Jared, and Patel, Aman B

Abstract

Purpose: Flow diverting stents have revolutionized the treatment of intracranial aneurysms through endoluminal reconstruction of the parent vessel. Despite this, certain aneurysms require retreatment. The purpose of this study was to identify clinical and radiologic determinants of aneurysm retreatment following flow diversion. Methods: A multicenter flow diversion database was evaluated to identify patients presenting with an unruptured, previously untreated aneurysm with a minimum of 12 months' clinical and angiographic follow-up. Univariate and multivariate logistic regression modeling was performed to identify determinants of retreatment. Results: We identified 189 aneurysms treated in 189 patients with a single flow-diverting stent. Mean age was 54 years, and 89% were female. Complete occlusion was achieved in 70.3% and 83.6% of patients at six and 12 months, respectively. Aneurysm retreatment with additional flow-diverting stents occurred in 5.8% of cases. Univariate analysis revealed that dome diameter ≥ 10 mm (p = 0.012), pre-clinoid internal carotid artery location (p = 0.012), distal > proximal parent vessel diameter (p = 0.042), and later dual antiplatelet therapy (DAPT) discontinuation (p < 0.001) were predictive of retreatment. Multivariate analysis identified discontinuation of DAPT > 12 months (p = 0.003) as a strong determinant of retreatment with dome diameter ≥ 10 mm trending toward statistical significance (p = 0.064). Large aneurysm neck diameter, presence of aneurysm branch vessels, patient age, smoking history, and hypertension were not determinant of retreatment on multivariate analysis. Conclusions: Prolonged DAPT is the most important determinant of aneurysm retreatment following single-device flow diversion. Abbreviating DAPT duration to only six months should be a consideration in this population, especially for patients with a large aneurysm dome diameter. [ABSTRACT FROM AUTHOR]

Published
2022
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46. Abstract P104: Incidence, Characteristics and Outcomes of Large Vessel Stroke in Covid-19: An International Multicenter Study

Author

Khandelwal, Priyank, primary, Al-Mufti, Fawaz, additional, Tiwari, Ambooj, additional, Singla, Amit, additional, Dmytriw, Adam A, additional, Piano, Mariangela, additional, Quilici, Luca, additional, Pero, Guglielmo, additional, Renieri, Leonardo, additional, Limbucci, Nicola, additional, Martinez-Galdamez, Mario, additional, Arenillas-Lara, Juan F, additional, Schuller, Miguel, additional, Galvan, Jorge, additional, Hashim, Zafar, additional, Nayak, Sanjeev, additional, DeSousa, Keith, additional, Sun, Hai, additional, Agarwalla, Pankaj K, additional, Nanda, Anil, additional, Roychowdhury, Sudipta, additional, Nourollahzadeh, Emad, additional, Prakash, Tannavi, additional, Efendizade, Aslan, additional, Gandhi, Chirag D, additional, Xavier, Andrew R, additional, Gupta, Gaurav, additional, and Yavagal, Dileep R, additional

Published
2021
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47. Cervical fusion for adult patients with atlantoaxial rotatory subluxation

Author

Spirollari, Eris, primary, Beaudreault, Cameron, additional, Ng, Christina, additional, Vazquez, Sima, additional, Chapman, Emily, additional, Clare, Kevin, additional, Wang, Richard, additional, Naftchi, Alexandria, additional, Das, Ankita, additional, Lui, Aiden, additional, Sacknovitz, Ariel, additional, Dominguez, Jose F., additional, Gandhi, Chirag D., additional, Tyagi, Rachana, additional, Houten, John K., additional, and Kinon, Merritt D., additional

Published
2021
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