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46 results on '"Fortin, R."'

1. Aerial Measurement of Radioxenon Concentration off the West Coast of Vancouver Island following the Fukushima Reactor Accident

Author

Sinclair, L. E., Seywerd, H. C. J., Fortin, R., Carson, J. M., Saull, P. R. B., Coyle, M. J., Van Brabant, R. A., Buckle, J. L., Desjardins, S. M., and Hall, R. M.

Subjects
Nuclear Experiment, Physics - Atmospheric and Oceanic Physics, Physics - Geophysics, Physics - Medical Physics
Abstract

In response to the Fukushima nuclear reactor accident, on March 20th, 2011, Natural Resources Canada conducted aerial radiation surveys over water just off of the west coast of Vancouver Island. Dose-rate levels were found to be consistent with background radiation, however a clear signal due to Xe-133 was observed. Methods to extract Xe-133 count rates from the measured spectra, and to determine the corresponding Xe-133 volumetric concentration, were developed. The measurements indicate that Xe-133 concentrations on average lie in the range of 30 to 70 Bq/m3., Comment: 14 pages, 5 figures, accepted for publication in Journal of Environmental Radioactivity

Published
2011
Full Text
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2. Role Representations at the Core of School Principals' Practices in the Midst of School Reform in Quebec.

Author

Savoie-Zajc, L., Brassard, A., Corriveau, L., Fortin, R., and Gelinas, A.

Abstract

The aim of this paper is to identify how school principals see their roles in the context of change dynamics brought about by school reform. The data come from a study funded by the Social Sciences and Humanities Research Council of Canada. The general research objective is to highlight "models of action" that school principals have developed through their years of professional experience. The researchers wish to pinpoint how those "models of action" are challenged when a major school reform is introduced and what kind of adjustments they have to make to their professional practices. Results show that there are eight types of relationships that capture school principals' visions of their roles in the context of change dynamics. Positive relationships include harmonizing diversity, collaborating, vision building, and decision-making. There are relationships tinged with emergency and danger, others characterized by movement and instability, and one describing a relationship of power and influence. These inner images allow proposing a more precise understanding of the subjective meaning principals attribute to their professional role. This understanding will be deepened when these representations can be linked to the intents and strategies underlying the principals'"models of action." (Contains 23 references.) (RT)

Published
2002

4. A GIF++ Gamma Irradiation Facility at the SPS H4 Beam Line

Author

Capéans-Garrido, M, Fortin, R, Linssen, L, Moll, M, and Rembser, C

Subjects
Physics::Instrumentation and Detectors, Physics::Accelerator Physics, Detectors and Experimental Techniques
Abstract

The current document describes a proposal to implement a new gamma irradiation facility, combined with a high-energy particle beam in the SPS H4 beam line in hall EHN1. This new GIF++ facility is motivated by strong needs from the LHC and sLHC detector and accelerator communities for the tests of LHC components and systems.

Published
2009

6. Status Report on the Construction of the Mechanical Outer Forward Module Prototypes for the SCT

Author

Fortin, R, Niinikoski, T O, Roe, S, Weilhammer, Peter, Clark, A G, Ferrère, D, Macina, Daniela, Morone, C, Perrin, E, Weber, M, and Zsenei, A

Subjects
Detectors and Experimental Techniques
Abstract

It is foreseen to assemble and test ~600 silicon detector modules of the Forward Silicon Tracker (SCT), using facilities at CERN and the University of Geneva. The mechanical tolerances of the modules being constructed are stringent, making the large scale fabrication of detector modules a challenge. An assembly procedure has been developed with the aim of meeting the required mechanical tolerances. The production of four prototype mechanical modules using this procedure is described. Improvements of the assembly technique planned for the production of future forward modules are outlined.

Published
2000

7. Engineering for the ATLAS SemiConductor Tracker (SCT) end-cap

Author

Abdesselam, A., Allport, P. P., Anderson, B., Andricek, L., Anghinolfi, F., Apsimon, R. J., Atkinson, T., Austin, A., Band, H., Barclay, P., Barr, A., Batchelor, L. E., Bates, R. L., Batley, J. R., Beck, G., Becker, H., Bell, P., Bell, W. H., Belymam, A., Benes, J., Benes, P., Berbee, E., Bernabeu, J., Bethke, S., Bingefors, Nils, Bizzell, J. P., Blaszczak, Z. J., Blocki, J., Broz, J., Bohm, J., Brenner, Richard, Brodbeck, T. J., de Renstrom, P. Bruckman, Buis, R., Burton, G., Buskop, J., Buttar, C. M., Butterworth, J. M., Butterworth, S., Capocci, E., Carpentieri, C., Carter, A. A., Carter, J. R., Chamizo, M., Charlton, D. G., Cheplakov, A., Chilingarov, A., Chouridou, S., Chren, D., Chu, M. L., Cindro, V., Ciocio, A., Civera, J. V., Clark, A., Coe, P., Colijn, A. P., Cooke, P. A., Costa, M. J., Costanzo, D., Curtis-Rous, M., Dabinett, C., Dabrowski, W., Dalmau, J., Danielsen, K. M., D'Auria, S., Dawson, I., de Jong, P., Dervan, P., Dobson, E., Doherty, F., Dolezal, Z., Donega, M., D'Onofrio, M., Dorholt, O., Doubrava, M., Duerdoth, I. P., Duisters, C., Duxfield, R., Dwuznik, M., Eckert, S., Eklund, L., Escobar, C., Evans, D. L., Fadeyev, V., Fasching, D., Feld, L., Ferguson, D. P. S., Ferrari, P., Ferrere, D., Fopma, J., Ford, P., Fortin, R., Foster, J. M., Fox, H., Fraser, T. J., Freestone, J., French, R. S., Fuster, J., Gallop, B. J., Galuska, M., Gannaway, F., Garcia, C., Garcia-Navarro, J. E., Gibson, M., Gibson, S., Gnanvo, K., Godlewski, J., Gonzalez, F., Gonzalez-Sevilla, S., Goodrick, M. J., Gorfine, G., Gorisek, A., Gornicki, E., Greenall, A., Greenfield, D., Gregory, S., Grillo, A. A., Grosse-Knetter, J., Gryska, C., Haddad, L., Hara, K., Harris, M., Hartjes, F. G., Hauff, D., Hawes, B., Hayler, T., Haywood, S. J., Heinemann, F., Heinzinger, K., Hessey, N. P., Heusch, C., Hicheur, A., Hill, J. C., Hodgkinson, M., Hodgson, P., Hollins, T. I., Holt, R., Homna, J., Horaziovsky, T., Howell, D., Hughes, G., Huse, T., Ibbotson, M., Ikegami, Y., Ilyashenko, I., Issever, C., Jakubek, J., Jackson, J. N., Jakobs, K., Jared, R. C., Jarron, P., Johansson, P., John, D., Jones, A., Jones, M., Jones, T. J., Joos, D., Joseph, J., Jovanovic, P., Jusko, J., Jusko, O., Kaplon, J., Karagoz-Unel, M., Ketterer, Ch., Kodys, P., Koffeman, E., Kohout, Z., Kohriki, T., Kok, H., Kondo, T., Koperny, S., Korporaal, A., Koukol, V., Kral, V., Kramberger, G., Kubik, P., Kudlaty, J., Kuilman, W., Kundu, N., Lacasta, C., Lacuesta, V., Lau, W., Lee, S. C., Leguyt, R., Leney, K., Lenz, S., Lester, C. G., Liang, Z., Liebicher, K., Limper, M., Lindquist, L. E., Lindsay, S., Linhart, V., Lintern, A., Locket, C., Lockwood, M., Loebinger, F. K., Lozano, M., Ludwig, I., Ludwig, J., Lutz, G., Maassen, M., Macina, D., Macpherson, A., MacWaters, C., Magrath, C. A., Malecki, P., Mandic, I., Mangin-Brinet, M., Marshall, G., Marti-Garcia, S., Martinez-McKinney, G. F. M., Matheson, J. P., McEwan, F., McMahon, S. J., McPhail, D., Meinhardt, J., Mellado, B., Mercer, I. J., Messmer, I., Mikulec, B., Mikuz, M., Mima, S., Mistry, K., Mitra, A., Mitsou, V. A., Modesto, P., Moed, S., Mohn, B., Moles, R., Moorhead, G. F., Moreno, B., Morin, J., Morris, J., Moser, H. G., Moszczynski, A., Muijs, A. J. M., Munneke, B., Murray, W. J., Muskett, D., Nacher, J., Nagai, K., Naito, D., Nakano, I., Nelson, C., Nichols, A., Nickerson, R. B., Nisius, R., Noviss, J., Olcese, M., O'Shea, V., Oye, O. K., Paganis, S., Palmer, M. J., Parker, M. A., Parzefall, U., Pater, J. R., Pernegger, H., Perrin, E., Phillips, A., Phillips, P. W., Pieron, J. P., Poltorak, K., Pospisil, S., Postranecky, M., Pritchard, T., Prokofiev, K., Raine, C., Ratoff, P. N., Reitmeijer, A., Reznicek, P., Richter, R. H., Robichaud-Veronneau, A., Robinson, D., Robson, A., Rodriguez-Oliete, R., Roe, S., Rolfe, G., Rovenkamp, J., Runge, K., Saavedra, A., Sadrozinski, H. F. W., Sanchez, F. J., Sandaker, H., Schieck, J., Schuijlenburg, H., Siegrist, J., Seiden, A., Sfyrla, A., Simm, G., Slatter, J., Slavieek, T., Smith, B., Smith, K. M., Smith, N. A., Snippe, C., Snow, S. W., Solar, M., Solberg, A. O., Sopko, B., Sopko, V., Sospedra, L., Southern, G. D., Sowinski, M., Spencer, E., Spieler, H., Stanecka, E., Stapnes, S., Stastny, J., Steckl, I., Stodulski, M., Strachko, V., Stradling, A., Stugu, B., Sutcliffe, P., Szczygiel, R., Takashima, R., Tanaka, R., Tappern, G., Tarrant, J., Taylor, G. N., Temple, S., Teng, P. K., Terada, S., Thompson, R. J., Thresher, N. E., Titov, M., Tovey, D. R., Tratzl, G., Tricoli, A., Turala, M., Turner, P. R., Tyndel, M., Ullan, M., Unno, Y., Vickey, T., Vacek, V., Van der Kraaij, E., Van Ovenbeek, M., Viehhauser, G., Vu, C., Villani, E. G., Anh, T. Vu, Vossebeld, J. H., Wachler, M., Wallny, R., Ward, C. P., Warren, M. R. M., Wastie, R., Weber, M., Weidberg, A. R., Weilhammer, P., Wells, P. S., Werneke, P., Wetzel, P., White, M. J., Wiesmann, M., Wilmut, I., Wilson, J. A., Wolter, M., Wormald, M. P., Wu, S. L., Wu, X., Zimmer, J., Zseneii, A., Zhu, H., Abdesselam, A., Allport, P. P., Anderson, B., Andricek, L., Anghinolfi, F., Apsimon, R. J., Atkinson, T., Austin, A., Band, H., Barclay, P., Barr, A., Batchelor, L. E., Bates, R. L., Batley, J. R., Beck, G., Becker, H., Bell, P., Bell, W. H., Belymam, A., Benes, J., Benes, P., Berbee, E., Bernabeu, J., Bethke, S., Bingefors, Nils, Bizzell, J. P., Blaszczak, Z. J., Blocki, J., Broz, J., Bohm, J., Brenner, Richard, Brodbeck, T. J., de Renstrom, P. Bruckman, Buis, R., Burton, G., Buskop, J., Buttar, C. M., Butterworth, J. M., Butterworth, S., Capocci, E., Carpentieri, C., Carter, A. A., Carter, J. R., Chamizo, M., Charlton, D. G., Cheplakov, A., Chilingarov, A., Chouridou, S., Chren, D., Chu, M. L., Cindro, V., Ciocio, A., Civera, J. V., Clark, A., Coe, P., Colijn, A. P., Cooke, P. A., Costa, M. J., Costanzo, D., Curtis-Rous, M., Dabinett, C., Dabrowski, W., Dalmau, J., Danielsen, K. M., D'Auria, S., Dawson, I., de Jong, P., Dervan, P., Dobson, E., Doherty, F., Dolezal, Z., Donega, M., D'Onofrio, M., Dorholt, O., Doubrava, M., Duerdoth, I. P., Duisters, C., Duxfield, R., Dwuznik, M., Eckert, S., Eklund, L., Escobar, C., Evans, D. L., Fadeyev, V., Fasching, D., Feld, L., Ferguson, D. P. S., Ferrari, P., Ferrere, D., Fopma, J., Ford, P., Fortin, R., Foster, J. M., Fox, H., Fraser, T. J., Freestone, J., French, R. S., Fuster, J., Gallop, B. J., Galuska, M., Gannaway, F., Garcia, C., Garcia-Navarro, J. E., Gibson, M., Gibson, S., Gnanvo, K., Godlewski, J., Gonzalez, F., Gonzalez-Sevilla, S., Goodrick, M. J., Gorfine, G., Gorisek, A., Gornicki, E., Greenall, A., Greenfield, D., Gregory, S., Grillo, A. A., Grosse-Knetter, J., Gryska, C., Haddad, L., Hara, K., Harris, M., Hartjes, F. G., Hauff, D., Hawes, B., Hayler, T., Haywood, S. J., Heinemann, F., Heinzinger, K., Hessey, N. P., Heusch, C., Hicheur, A., Hill, J. C., Hodgkinson, M., Hodgson, P., Hollins, T. I., Holt, R., Homna, J., Horaziovsky, T., Howell, D., Hughes, G., Huse, T., Ibbotson, M., Ikegami, Y., Ilyashenko, I., Issever, C., Jakubek, J., Jackson, J. N., Jakobs, K., Jared, R. C., Jarron, P., Johansson, P., John, D., Jones, A., Jones, M., Jones, T. J., Joos, D., Joseph, J., Jovanovic, P., Jusko, J., Jusko, O., Kaplon, J., Karagoz-Unel, M., Ketterer, Ch., Kodys, P., Koffeman, E., Kohout, Z., Kohriki, T., Kok, H., Kondo, T., Koperny, S., Korporaal, A., Koukol, V., Kral, V., Kramberger, G., Kubik, P., Kudlaty, J., Kuilman, W., Kundu, N., Lacasta, C., Lacuesta, V., Lau, W., Lee, S. C., Leguyt, R., Leney, K., Lenz, S., Lester, C. G., Liang, Z., Liebicher, K., Limper, M., Lindquist, L. E., Lindsay, S., Linhart, V., Lintern, A., Locket, C., Lockwood, M., Loebinger, F. K., Lozano, M., Ludwig, I., Ludwig, J., Lutz, G., Maassen, M., Macina, D., Macpherson, A., MacWaters, C., Magrath, C. A., Malecki, P., Mandic, I., Mangin-Brinet, M., Marshall, G., Marti-Garcia, S., Martinez-McKinney, G. F. M., Matheson, J. P., McEwan, F., McMahon, S. J., McPhail, D., Meinhardt, J., Mellado, B., Mercer, I. J., Messmer, I., Mikulec, B., Mikuz, M., Mima, S., Mistry, K., Mitra, A., Mitsou, V. A., Modesto, P., Moed, S., Mohn, B., Moles, R., Moorhead, G. F., Moreno, B., Morin, J., Morris, J., Moser, H. G., Moszczynski, A., Muijs, A. J. M., Munneke, B., Murray, W. J., Muskett, D., Nacher, J., Nagai, K., Naito, D., Nakano, I., Nelson, C., Nichols, A., Nickerson, R. B., Nisius, R., Noviss, J., Olcese, M., O'Shea, V., Oye, O. K., Paganis, S., Palmer, M. J., Parker, M. A., Parzefall, U., Pater, J. R., Pernegger, H., Perrin, E., Phillips, A., Phillips, P. W., Pieron, J. P., Poltorak, K., Pospisil, S., Postranecky, M., Pritchard, T., Prokofiev, K., Raine, C., Ratoff, P. N., Reitmeijer, A., Reznicek, P., Richter, R. H., Robichaud-Veronneau, A., Robinson, D., Robson, A., Rodriguez-Oliete, R., Roe, S., Rolfe, G., Rovenkamp, J., Runge, K., Saavedra, A., Sadrozinski, H. F. W., Sanchez, F. J., Sandaker, H., Schieck, J., Schuijlenburg, H., Siegrist, J., Seiden, A., Sfyrla, A., Simm, G., Slatter, J., Slavieek, T., Smith, B., Smith, K. M., Smith, N. A., Snippe, C., Snow, S. W., Solar, M., Solberg, A. O., Sopko, B., Sopko, V., Sospedra, L., Southern, G. D., Sowinski, M., Spencer, E., Spieler, H., Stanecka, E., Stapnes, S., Stastny, J., Steckl, I., Stodulski, M., Strachko, V., Stradling, A., Stugu, B., Sutcliffe, P., Szczygiel, R., Takashima, R., Tanaka, R., Tappern, G., Tarrant, J., Taylor, G. N., Temple, S., Teng, P. K., Terada, S., Thompson, R. J., Thresher, N. E., Titov, M., Tovey, D. R., Tratzl, G., Tricoli, A., Turala, M., Turner, P. R., Tyndel, M., Ullan, M., Unno, Y., Vickey, T., Vacek, V., Van der Kraaij, E., Van Ovenbeek, M., Viehhauser, G., Vu, C., Villani, E. G., Anh, T. Vu, Vossebeld, J. H., Wachler, M., Wallny, R., Ward, C. P., Warren, M. R. M., Wastie, R., Weber, M., Weidberg, A. R., Weilhammer, P., Wells, P. S., Werneke, P., Wetzel, P., White, M. J., Wiesmann, M., Wilmut, I., Wilson, J. A., Wolter, M., Wormald, M. P., Wu, S. L., Wu, X., Zimmer, J., Zseneii, A., and Zhu, H.

Abstract

The ATLAS SemiConductor Tracker (SCT) is a silicon-strip tracking detector which forms part of the ATLAS inner detector. The SCT is designed to track charged particles produced in proton-proton collisions at the Large Hadron Collider (LHC) at CERN at an energy of 14 TeV. The tracker is made up of a central barrel and two identical end-caps. The barrel contains 2112 silicon modules, while each end-cap contains 988 modules. The overall tracking performance depends not only on the intrinsic measurement precision of the modules but also on the characteristics of the whole assembly, in particular, the stability and the total material budget. This paper describes the engineering design and construction of the SCT end-caps, which are required to support mechanically the silicon modules, supply services to them and provide a suitable environment within the inner detector. Critical engineering choices are highlighted and innovative solutions are presented - these will be of interest to other builders of large-scale tracking detectors. The SCT end-caps will be fully connected at the start of 2008. Further commissioning will continue, to be ready for proton-proton collision data in 2008.

Published
2008
Full Text
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8. The ATLAS semiconductor tracker end-cap module

Author

Abdesselam, A., Adkin, P. J., Allport, P. P., Alonso, J., Andricek, L., Anghinolfi, F., Antonov, A. A., Apsimon, R. J., Atkinson, T., Batchelor, L. E., Bates, R. L., Beck, G., Becker, H., Bell, P., Bell, W., Benes, P., Bernabeu, J., Bethke, S., Bizzell, J. P., Blocki, J., Broklova, Z., Broz, J., Bohm, J., Booker, P., Bright, G., Brodbeck, T. J., Bruckman, P., Buttari, C. M., Butterworth, J. M., Campabadal, F., Campbell, D., Carpentier, C., Carroll, J. L., Carter, A. A., Carter, J. R., Casse, G. L., Cermak, P., Chamizo, M., Charlton, D. G., Cheplakov, A., Chesi, E., Chilingarov, A., Chouridou, S., Chren, D., Christinet, A., Chu, M. L., Cindro, V., Clocio, A., Civera, J. V., Clark, A., Colijn, A. P., Cooke, P. A., Costa, M. J., Costanzo, D., Dabrowski, W., Danielsen, K. M., Davies, V. R., Dawson, I., de Jong, P., Dervan, P., Doherty, F., Dolezal, Z., Donega, M., D'Onofrio, M., Dorholt, O., Drasal, Z., Dowell, J. D., Duerdoth, I. P., Duxfield, R., Dwuznik, M., Easton, J. M., Eckert, S., Eklund, L., Escobar, C., Fadeyev, V., Fasching, D., Feld, L., Ferguson, D. P. S., Ferrari, P., Ferrere, D., Fleta, C., Fortin, R., Foster, J. M., Fowler, C., Fox, H., Freestone, J., French, R. S., Fuster, J., Gadomski, S., Gallop, B. J., Garcia, C., Garcia-Navarro, J. E., Gibson, S., Gilchriese, M. G. D., Gonzalez, F., Gonzalez-Sevilla, S., Goodrick, M. J., Gorisek, A., Gornicki, E., Greenall, A., Greenfield, D., Gregory, S., Grigorieva, I. G., Grillo, A. A., Grosse-Knetter, J., Gryska, C., Guipet, A., Haber, C., Hara, K., Hartjes, F. G., Hauff, D., Haywood, S. J., Hegeman, S. J., Heinzinger, K., Hessey, N. P., Heusch, C., Hicheur, A., Hill, J. C., Hodgkinson, M., Hodgson, P., Horazdovsky, T., Hollins, T. I., Hou, L. S., Hou, S., Hughes, G., Huse, T., Ibbotson, M., Iglesias, M., Ikegami, Y., Ilyashenko, I., Issever, C., Jackson, J. N., Jakobs, K., Jared, R. C., Jarron, P., Johansson, P., Jones, R. W. L., Jones, T. J., Joos, D., Joseph, J., Jovanovic, P., Jusko, O., Jusko, V., Kaplon, J., Kazi, S., Ketterer, Ch., Kholodenko, A. G., King, B. T., Kodys, P., Koffeman, E., Kohout, Z., Kohriki, T., Kondo, T., Koperny, S., Koukol, H., Kral, V., Kramberger, G., Kubik, P., Kudlaty, J., Lacasta, C., Lagouri, T., Lee, S. C., Leney, K., Lenz, S., Lester, C. G., Liebicher, K., Limper, M., Lindsay, S., Linhart, V., Llosa, G., Loebinger, F. K., Lozano, M., Ludwig, I., Ludwig, J., Lutz, G., Lys, J., Maassen, M., Macina, D., Macpherson, A., MacWaters, C., Magrath, C. A., Malecki, P., Mandic, I., Mangin-Brinet, M., Marti-Garcia, S., Matheson, J. P., Matson, R. M., McMahon, S. J., McMahon, T. J., Meinhardt, J., Mellado, B., Melone, J. J., Mercer, I. J., Messmer, I., Mikulec, B., Mikuz, M., Minano, M., Mitsouak, V. A., Modesto, P., Moed, S., Mohn, B., Moncrieff, S., Moorhead, G., Morris, F. S., Morris, J., Morrissey, M., Moser, H. G., Moszczynski, A., Muijs, A. J. M., Murray, W. J., Muskett, D., Nacher, J., Nagai, K., Nakano, I., Nickerson, R. B., Nisius, R., Oye, O. K., O'Shea, V., Paganis, E., Parker, M. A., Parzefall, U., Pater, J. R., Peeters, S. J. M., Pellegrini, G., Pelleriti, G., Pernegger, H., Perrin, E., Phillips, P. W., Pilavova, L. V., Poltorak, K., Pospisil, S., Postranecky, M., Pritchard, T., Prokofiev, K., Rafi, J. M., Raine, C., Ratoff, P. N., Reznicek, P., Riadovikov, V. N., Richter, R. H., Robichaud-Veronneau, A., Robinson, D., Rodriguez-Oliete, R., Roe, S., Rudge, A., Runge, K., Saavedra, A., Sadrozinski, H. F. W., Sanchez, F. J., Sandaker, H., Saxon, D. H., Scheirich, D., Schieck, J., Seiden, A., Sfyrla, A., Slavicek, T., Smith, K. M., Smith, N. A., Snow, S. W., Solar, M., Sopko, B., Sopko, V., Sospedra, L., Spencer, E., Stanecka, E., Stapnes, S., Stastny, J., Strachko, V., Stradling, A., Stugu, B., Su, D. S., Sutcliffe, P., Szczygiel, R., Tanaka, R., Taylor, G., Teng, P. K., Terada, S., Thompson, R. J., Titov, M., Toczek, B., Tovey, D. R., Tratzl, G., Troitsky, V. L., Tseng, J., Turala, M., Turner, P. R., Tyndel, M., Ullan, M., Unno, Y., Vickey, T., Van der Kraaij, E., Viehhauser, G., Villani, E. G., Vitek, T., Anh, T. Vu, Vorobiev, A. P., Vossebeld, J. H., Wachler, M., Wallny, R., Ward, C. P., Warren, M. R. M., Webel, M., Weber, M., Weidberg, A. R., Weilhammer, P., Wells, P. S., Wetzel, P., Whitley, M., Wiesmann, M., Wilhelm, I., Willenbrock, M., Wilmut, I., Wilson, J. A., Winton, J., Wolter, M., Wormald, M. P., Wu, S. L., Wu, X., Zhu, H., Bingefors, Nils, Brenner, Richard, Ekelöf, Tord, Abdesselam, A., Adkin, P. J., Allport, P. P., Alonso, J., Andricek, L., Anghinolfi, F., Antonov, A. A., Apsimon, R. J., Atkinson, T., Batchelor, L. E., Bates, R. L., Beck, G., Becker, H., Bell, P., Bell, W., Benes, P., Bernabeu, J., Bethke, S., Bizzell, J. P., Blocki, J., Broklova, Z., Broz, J., Bohm, J., Booker, P., Bright, G., Brodbeck, T. J., Bruckman, P., Buttari, C. M., Butterworth, J. M., Campabadal, F., Campbell, D., Carpentier, C., Carroll, J. L., Carter, A. A., Carter, J. R., Casse, G. L., Cermak, P., Chamizo, M., Charlton, D. G., Cheplakov, A., Chesi, E., Chilingarov, A., Chouridou, S., Chren, D., Christinet, A., Chu, M. L., Cindro, V., Clocio, A., Civera, J. V., Clark, A., Colijn, A. P., Cooke, P. A., Costa, M. J., Costanzo, D., Dabrowski, W., Danielsen, K. M., Davies, V. R., Dawson, I., de Jong, P., Dervan, P., Doherty, F., Dolezal, Z., Donega, M., D'Onofrio, M., Dorholt, O., Drasal, Z., Dowell, J. D., Duerdoth, I. P., Duxfield, R., Dwuznik, M., Easton, J. M., Eckert, S., Eklund, L., Escobar, C., Fadeyev, V., Fasching, D., Feld, L., Ferguson, D. P. S., Ferrari, P., Ferrere, D., Fleta, C., Fortin, R., Foster, J. M., Fowler, C., Fox, H., Freestone, J., French, R. S., Fuster, J., Gadomski, S., Gallop, B. J., Garcia, C., Garcia-Navarro, J. E., Gibson, S., Gilchriese, M. G. D., Gonzalez, F., Gonzalez-Sevilla, S., Goodrick, M. J., Gorisek, A., Gornicki, E., Greenall, A., Greenfield, D., Gregory, S., Grigorieva, I. G., Grillo, A. A., Grosse-Knetter, J., Gryska, C., Guipet, A., Haber, C., Hara, K., Hartjes, F. G., Hauff, D., Haywood, S. J., Hegeman, S. J., Heinzinger, K., Hessey, N. P., Heusch, C., Hicheur, A., Hill, J. C., Hodgkinson, M., Hodgson, P., Horazdovsky, T., Hollins, T. I., Hou, L. S., Hou, S., Hughes, G., Huse, T., Ibbotson, M., Iglesias, M., Ikegami, Y., Ilyashenko, I., Issever, C., Jackson, J. N., Jakobs, K., Jared, R. C., Jarron, P., Johansson, P., Jones, R. W. L., Jones, T. J., Joos, D., Joseph, J., Jovanovic, P., Jusko, O., Jusko, V., Kaplon, J., Kazi, S., Ketterer, Ch., Kholodenko, A. G., King, B. T., Kodys, P., Koffeman, E., Kohout, Z., Kohriki, T., Kondo, T., Koperny, S., Koukol, H., Kral, V., Kramberger, G., Kubik, P., Kudlaty, J., Lacasta, C., Lagouri, T., Lee, S. C., Leney, K., Lenz, S., Lester, C. G., Liebicher, K., Limper, M., Lindsay, S., Linhart, V., Llosa, G., Loebinger, F. K., Lozano, M., Ludwig, I., Ludwig, J., Lutz, G., Lys, J., Maassen, M., Macina, D., Macpherson, A., MacWaters, C., Magrath, C. A., Malecki, P., Mandic, I., Mangin-Brinet, M., Marti-Garcia, S., Matheson, J. P., Matson, R. M., McMahon, S. J., McMahon, T. J., Meinhardt, J., Mellado, B., Melone, J. J., Mercer, I. J., Messmer, I., Mikulec, B., Mikuz, M., Minano, M., Mitsouak, V. A., Modesto, P., Moed, S., Mohn, B., Moncrieff, S., Moorhead, G., Morris, F. S., Morris, J., Morrissey, M., Moser, H. G., Moszczynski, A., Muijs, A. J. M., Murray, W. J., Muskett, D., Nacher, J., Nagai, K., Nakano, I., Nickerson, R. B., Nisius, R., Oye, O. K., O'Shea, V., Paganis, E., Parker, M. A., Parzefall, U., Pater, J. R., Peeters, S. J. M., Pellegrini, G., Pelleriti, G., Pernegger, H., Perrin, E., Phillips, P. W., Pilavova, L. V., Poltorak, K., Pospisil, S., Postranecky, M., Pritchard, T., Prokofiev, K., Rafi, J. M., Raine, C., Ratoff, P. N., Reznicek, P., Riadovikov, V. N., Richter, R. H., Robichaud-Veronneau, A., Robinson, D., Rodriguez-Oliete, R., Roe, S., Rudge, A., Runge, K., Saavedra, A., Sadrozinski, H. F. W., Sanchez, F. J., Sandaker, H., Saxon, D. H., Scheirich, D., Schieck, J., Seiden, A., Sfyrla, A., Slavicek, T., Smith, K. M., Smith, N. A., Snow, S. W., Solar, M., Sopko, B., Sopko, V., Sospedra, L., Spencer, E., Stanecka, E., Stapnes, S., Stastny, J., Strachko, V., Stradling, A., Stugu, B., Su, D. S., Sutcliffe, P., Szczygiel, R., Tanaka, R., Taylor, G., Teng, P. K., Terada, S., Thompson, R. J., Titov, M., Toczek, B., Tovey, D. R., Tratzl, G., Troitsky, V. L., Tseng, J., Turala, M., Turner, P. R., Tyndel, M., Ullan, M., Unno, Y., Vickey, T., Van der Kraaij, E., Viehhauser, G., Villani, E. G., Vitek, T., Anh, T. Vu, Vorobiev, A. P., Vossebeld, J. H., Wachler, M., Wallny, R., Ward, C. P., Warren, M. R. M., Webel, M., Weber, M., Weidberg, A. R., Weilhammer, P., Wells, P. S., Wetzel, P., Whitley, M., Wiesmann, M., Wilhelm, I., Willenbrock, M., Wilmut, I., Wilson, J. A., Winton, J., Wolter, M., Wormald, M. P., Wu, S. L., Wu, X., Zhu, H., Bingefors, Nils, Brenner, Richard, and Ekelöf, Tord

Abstract

The challenges for the tracking detector systems at the LHC are unprecedented in terms of the number of channels, the required read-out speed and the expected radiation levels. The ATLAS Semiconductor Tracker. (SCT) end-caps have a total of about 3 million electronics channels each reading out every 25 ns into its own on-chip 3.3 mu s buffer. The highest anticipated dose after 10 years operation is 1.4x10(14) cm(-2) in units of 1 MeV neutron equivalent (assuming the damage factors scale with the non-ionising energy loss). The forward tracker has 1976 double-sided modules, mostly of area similar to 70 cm(2), each having 2 x 768 strips read out by six ASICs per side. The requirement to achieve an average perpendicular radiation length of 1.5% X-0, while coping with up to 7 W dissipation per module (after irradiation), leads to stringent constraints on the thermal design. The additional requirement of 1500e(-) equivalent noise charge (ENC) rising to only 1800e(-) ENC after irradiation, provides stringent design constraints on both the high-density Cu/Polyimide flex read-out circuit and the ABCD3TA read-out ASICs. Finally, the accuracy of module assembly must not compromise the 16 mu m (r phi) resolution perpendicular to the strip directions or 580 mu m radial resolution coming from the 40 mrad front-back stereo angle. A total of 2210 modules were built to the tight tolerances and specifications required for the SCT. This was 234 more than the 1976 required and represents a yield of 93%. The component flow was at times tight, but the module production rate of 40-50 per week was maintained despite this. The distributed production was not found to be a major logistical problem and it allowed additional flexibility to take advantage of where the effort was available, including any spare capacity, for building the end-cap modules. The collaboration that produced the ATLAS SCT end-cap modules kept in close contact at all times so that the effects of shortages or stoppages at

Published
2007
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9. The barrel modules of the ATLAS semiconductor tracker

Author

Abdesselam, A., Akimoto, T., Allport, P. P., Alonso, J., Anderson, B., Andricek, L., Anghinolfi, F., Apsimon, R. J., Barbier, G., Barr, A. J., Batchelor, L. E., Bates, R. L., Batley, J. R., Beck, G. A., Bell, P. J., Belymam, A., Bernabeu, J., Bethke, S., Bizzell, J. P., Bohm, J., Brenner, Richard, Brodbeck, T. J., Broklova, Z., Broz, J., De Renstrom, P. Bruckman, Buttar, C. M., Butterworth, J. M., Carpentieri, C., Carter, A. A., Carter, J. R., Charlton, D. G., Cheplakov, A., Chesi, E., Chilingarov, A., Chouridou, S., Chu, M. L., Cindro, V., Ciocio, A., Civera, J. V., Clark, A., Coe, P., Colijn, A-P, Cornelissen, T., Cosgrove, D. P., Costa, M. J., Dabrowski, W., Dalmau, J., Danielsen, K. M., Dawson, I., Demirkoz, B., Dervan, P., Dolezal, Z., Donega, M., D'Onofrio, M., Dorholt, O., Dowell, J. D., Drasal, Z., Duerdoth, I. P., Dwuznik, M., Eckert, S., Ekelöf, Tord, Eklund, Lars, Escobar, C., Fadeyev, V., Feld, L., Ferrari, P., Ferrere, D., Fiorini, L., Fortin, R., Foster, J. M., Fox, H., Fraser, T. J., Freestone, J., French, R., Fuster, J., Gadomski, S., Gallop, B. J., Garcia, C., Garcia-Navarro, J. E., Gibson, M. D., Gibson, S., Gilchriese, M. G. D., Godlewski, J., Gonzalez-Sevilla, S., Goodrick, M. J., Gorisek, A., Gornicki, E., Greenall, A., Grigson, C., Grillo, A. A., Grosse-Knetter, J., Haber, C., Hara, K., Hartjes, F. G., Hauff, D., Hawes, B. M., Haywood, S. J., Hessey, N. P., Hicheur, A., Hill, J. C., Hollins, T. I., Holt, R., Howell, D. F., Hughes, G., Huse, T., Ibbotson, M., Ikegami, Y., Issever, C., Jackson, J. N., Jakobs, K., Jarron, P., Johansen, L. G., Jones, T. J., Jones, T. W., de Jong, P., Joos, D., Jovanovic, P., Kachiguine, S., Kaplon, J., Kato, Y., Ketterer, C., Kobayashi, H., Kodys, P., Koffeman, E., Kohout, Z., Kohriki, T., Kondo, T., Koperny, S., Kramberger, G., Kubik, P., Kudlaty, J., Kuwano, T., Lacasta, C., LaMarra, D., Lane, J. B., Lee, S. -C, Lester, C. G., Limper, M., Lindsay, S., Llatas, M. C., Loebinger, F. K., Lozano, M., Ludwig, I., Ludwig, J., Lutz, G., Lys, J., Maassen, M., Macina, D., Macpherson, A., MacWaters, C., McMahon, S. J., McMahon, T. J., Magrath, C. A., Malecki, P., Mandic, I., Mangin-Brinet, M., Marti-Garcia, S., Martinez-Mckinney, G. F. M., Matheson, J. M. C., Matson, R. M., Meinhardt, J., Mikulec, B., Mikuz, M., Minagawa, M., Mistry, J., Mitsou, V., Modesto, P., Moed, S., Mohn, B., Moorhead, G., Morin, J., Morris, J., Morrissey, M., Moser, H-G, Muijs, A. J. M., Murray, W. J., Nagai, K., Nakamura, K., Nakamura, Y., Nakano, I., Nichols, A., Nicholson, R., Nickerson, R. B., Nisius, R., O'Shea, V., Oye, O. K., Palmer, M. J., Parker, M. A., Parzefall, U., Pater, J. R., Peeters, S. J. M., Pellegrini, G., Pernegger, H., Perrin, E., Phillips, A., Phillips, P. W., Poltorak, K., Pospisil, S., Postranecky, M., Pritchard, T., Rafi, J. M., Ratoff, P. N., Reznicek, P., Richter, R. H., Robinson, D., Roe, S., Rosenbaum, F., Rudge, A., Runge, K., Sadrozinski, H. F. W., Sandaker, H., Saxon, D. H., Schieck, J., Sedlak, K., Seiden, A., Sengoku, H., Sfyrla, A., Shimma, S., Smith, K. M., Smith, N. A., Snow, S. W., Solar, M., Solberg, A., Sopko, B., Sospedra, L., Spencer, E., Stanecka, E., Stapnes, S., Stastny, J., Stodulski, M., Stugu, B., Szczygiel, R., Tanaka, R., Tappern, G., Taylor, G., Teng, P. K., Terada, S., Thompson, R. J., Titov, M., Toczek, B., Tovey, D. R., Tricoli, A., Turala, M., Turner, P. R., Tyndel, M., Ullan, M., Unno, Y., Van der Kraaij, E., van Vulpens, I., Viehhauser, G., Villani, E. G., Vorobel, V., Vos, M., Wallny, R., Warren, M. R. M., Wastie, R. L., Weber, M., Weidberg, A. R., Weilhammer, P., Wells, P. S., Wilder, M., Wilhelm, I., Wilson, J. A., Wolter, M., Abdesselam, A., Akimoto, T., Allport, P. P., Alonso, J., Anderson, B., Andricek, L., Anghinolfi, F., Apsimon, R. J., Barbier, G., Barr, A. J., Batchelor, L. E., Bates, R. L., Batley, J. R., Beck, G. A., Bell, P. J., Belymam, A., Bernabeu, J., Bethke, S., Bizzell, J. P., Bohm, J., Brenner, Richard, Brodbeck, T. J., Broklova, Z., Broz, J., De Renstrom, P. Bruckman, Buttar, C. M., Butterworth, J. M., Carpentieri, C., Carter, A. A., Carter, J. R., Charlton, D. G., Cheplakov, A., Chesi, E., Chilingarov, A., Chouridou, S., Chu, M. L., Cindro, V., Ciocio, A., Civera, J. V., Clark, A., Coe, P., Colijn, A-P, Cornelissen, T., Cosgrove, D. P., Costa, M. J., Dabrowski, W., Dalmau, J., Danielsen, K. M., Dawson, I., Demirkoz, B., Dervan, P., Dolezal, Z., Donega, M., D'Onofrio, M., Dorholt, O., Dowell, J. D., Drasal, Z., Duerdoth, I. P., Dwuznik, M., Eckert, S., Ekelöf, Tord, Eklund, Lars, Escobar, C., Fadeyev, V., Feld, L., Ferrari, P., Ferrere, D., Fiorini, L., Fortin, R., Foster, J. M., Fox, H., Fraser, T. J., Freestone, J., French, R., Fuster, J., Gadomski, S., Gallop, B. J., Garcia, C., Garcia-Navarro, J. E., Gibson, M. D., Gibson, S., Gilchriese, M. G. D., Godlewski, J., Gonzalez-Sevilla, S., Goodrick, M. J., Gorisek, A., Gornicki, E., Greenall, A., Grigson, C., Grillo, A. A., Grosse-Knetter, J., Haber, C., Hara, K., Hartjes, F. G., Hauff, D., Hawes, B. M., Haywood, S. J., Hessey, N. P., Hicheur, A., Hill, J. C., Hollins, T. I., Holt, R., Howell, D. F., Hughes, G., Huse, T., Ibbotson, M., Ikegami, Y., Issever, C., Jackson, J. N., Jakobs, K., Jarron, P., Johansen, L. G., Jones, T. J., Jones, T. W., de Jong, P., Joos, D., Jovanovic, P., Kachiguine, S., Kaplon, J., Kato, Y., Ketterer, C., Kobayashi, H., Kodys, P., Koffeman, E., Kohout, Z., Kohriki, T., Kondo, T., Koperny, S., Kramberger, G., Kubik, P., Kudlaty, J., Kuwano, T., Lacasta, C., LaMarra, D., Lane, J. B., Lee, S. -C, Lester, C. G., Limper, M., Lindsay, S., Llatas, M. C., Loebinger, F. K., Lozano, M., Ludwig, I., Ludwig, J., Lutz, G., Lys, J., Maassen, M., Macina, D., Macpherson, A., MacWaters, C., McMahon, S. J., McMahon, T. J., Magrath, C. A., Malecki, P., Mandic, I., Mangin-Brinet, M., Marti-Garcia, S., Martinez-Mckinney, G. F. M., Matheson, J. M. C., Matson, R. M., Meinhardt, J., Mikulec, B., Mikuz, M., Minagawa, M., Mistry, J., Mitsou, V., Modesto, P., Moed, S., Mohn, B., Moorhead, G., Morin, J., Morris, J., Morrissey, M., Moser, H-G, Muijs, A. J. M., Murray, W. J., Nagai, K., Nakamura, K., Nakamura, Y., Nakano, I., Nichols, A., Nicholson, R., Nickerson, R. B., Nisius, R., O'Shea, V., Oye, O. K., Palmer, M. J., Parker, M. A., Parzefall, U., Pater, J. R., Peeters, S. J. M., Pellegrini, G., Pernegger, H., Perrin, E., Phillips, A., Phillips, P. W., Poltorak, K., Pospisil, S., Postranecky, M., Pritchard, T., Rafi, J. M., Ratoff, P. N., Reznicek, P., Richter, R. H., Robinson, D., Roe, S., Rosenbaum, F., Rudge, A., Runge, K., Sadrozinski, H. F. W., Sandaker, H., Saxon, D. H., Schieck, J., Sedlak, K., Seiden, A., Sengoku, H., Sfyrla, A., Shimma, S., Smith, K. M., Smith, N. A., Snow, S. W., Solar, M., Solberg, A., Sopko, B., Sospedra, L., Spencer, E., Stanecka, E., Stapnes, S., Stastny, J., Stodulski, M., Stugu, B., Szczygiel, R., Tanaka, R., Tappern, G., Taylor, G., Teng, P. K., Terada, S., Thompson, R. J., Titov, M., Toczek, B., Tovey, D. R., Tricoli, A., Turala, M., Turner, P. R., Tyndel, M., Ullan, M., Unno, Y., Van der Kraaij, E., van Vulpens, I., Viehhauser, G., Villani, E. G., Vorobel, V., Vos, M., Wallny, R., Warren, M. R. M., Wastie, R. L., Weber, M., Weidberg, A. R., Weilhammer, P., Wells, P. S., Wilder, M., Wilhelm, I., Wilson, J. A., and Wolter, M.

Abstract

This paper describes the silicon microstrip modules in the barrel section of the SemiConductor Tracker (SCT) of the ATLAS experiment at the CERN Large Hadron Collider (LHC). The module requirements, components and assembly techniques are given, as well as first results of the module performance on the fully assembled barrels that make up the detector being installed in the ATLAS experiment.

Published
2006
Full Text
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13. Double Discharge TEA Laser Beams

Author

DEFENCE RESEARCH ESTABLISHMENT VALCARTIER QUEBEC, Fortin,R., Laflamme,A. K., Rheault,F., DEFENCE RESEARCH ESTABLISHMENT VALCARTIER QUEBEC, Fortin,R., Laflamme,A. K., and Rheault,F.

Abstract

The energy and power density distributions of a multi-transverse mode laser beam are predicted from a simple theoretical model. The corresponding experimental verifications show a good agreement for both the near and far field behavior of these beams. Finally, a method for optimizing the peak power density in the focal volume of a converging element is suggested. (Author), Summary in French. See also AD-780 839.

Published
1974

14. Reagent schemes for cost effective optimisation of plant performance.

Author

Kasumpa G., XVI international mineral processing congress Stockholm, Sweden 05-Jun-8810-Jun-88, Fortin R., Pillai J., Roe W., Kasumpa G., XVI international mineral processing congress Stockholm, Sweden 05-Jun-8810-Jun-88, Fortin R., Pillai J., and Roe W.

Abstract

The paper details the development of optimised chemical treatment schemes for mineral and coal processing using a systems approach. The importance of understanding the actions of the chemicals and their effects downstream is discussed along with other technical considerations. Chemical treatment schemes for coal, bauxite, gold, and sulphide copper ores are covered., The paper details the development of optimised chemical treatment schemes for mineral and coal processing using a systems approach. The importance of understanding the actions of the chemicals and their effects downstream is discussed along with other technical considerations. Chemical treatment schemes for coal, bauxite, gold, and sulphide copper ores are covered.

Published
1988

16. Preliminary Measurements of a Transversely Excited Atmospheric Pressure CO2 Laser

Author

DEFENCE RESEARCH ESTABLISHMENT VALCARTIER QUEBEC, Fortin,R., DEFENCE RESEARCH ESTABLISHMENT VALCARTIER QUEBEC, and Fortin,R.

Abstract

The design parameters of a transversely excited atmospheric pressure CO2 laser using 1000 ohm ballast resistors are determined from a series of energy measurements. Peak powers of the order of 1 MW/sq cm at the output window are achieved while the efficiency ranges from 3 to 5% (plus or minus 0.3). Improvements based on geometrical and electrical considerations are also suggested. (Author)

Published
1970

17. Problem Statement Language and Analyzer Concepts and Recommendations

Author

MITRE CORP BEDFORD MA, Fortin, R. J., MITRE CORP BEDFORD MA, and Fortin, R. J.

Abstract

The Information System Design and Optimization System (ISDOS), under development at the University of Michigan, offers automated assistance for the design of information processing systems (IPS). The Problem Statement Language (PSL) and Problem Statement Analyzer (PSA) are the components of ISDOS which are used for IPS requirements definition and analysis. This report describes the ISDOS project in general and the concepts, capabilities, and use of PSL/PSA. The report also describes future PSL/PSA development plans and makes recommendations for a detailed study to determine PSL/PSA's functional value.

Published
1973

18. Saturation Properties of TEA-CO2 Amplifiers in the Nanosecond Pulse Regime

Author

DEFENCE RESEARCH ESTABLISHMENT VALCARTIER QUEBEC, Rheault,F., Lachambre,J. L., Gilbert,J., Fortin,R., Blanchard,M., DEFENCE RESEARCH ESTABLISHMENT VALCARTIER QUEBEC, Rheault,F., Lachambre,J. L., Gilbert,J., Fortin,R., and Blanchard,M.

Abstract

Experimental data are presented for the energy extraction of a nanosecond pulse propagating with different energy flux densities in a grid-type double-discharge TEA-CO2 amplifier. The results show that the amplifying medium behaves essentially as a two-level system with a saturation energy of 155 mJ/sq cm. (Author)

Published
1973

19. Powerful Nanosecond Pulses by Stable Passive Mode-Locking of TEA CO2 Lasers

Author

DEFENCE RESEARCH ESTABLISHMENT VALCARTIER QUEBEC, Fortin,R., Rheault,F., Gilbert,J., Blanchard,M., Lachambre,J. L., DEFENCE RESEARCH ESTABLISHMENT VALCARTIER QUEBEC, Fortin,R., Rheault,F., Gilbert,J., Blanchard,M., and Lachambre,J. L.

Abstract

Passive mode-locking of a double-discharge TEA CO2 laser using SF6 as bleachable absorber has been achieved. Stable pulses shorter than 2 ns and having peak powers in the 100-200 MW range have been regularly obtained. The experimental conditions and operating characteristics of the laser required to achieve stability are described. (Author)

Published
1972

20. Dynamics of the CO2 Atmospheric Pressure Laser with Transverse Pulse Excitation

Author

DEFENCE RESEARCH ESTABLISHMENT VALCARTIER QUEBEC, Gilbert,J., Lachambre,J. L., Rheault,F., Fortin,R., DEFENCE RESEARCH ESTABLISHMENT VALCARTIER QUEBEC, Gilbert,J., Lachambre,J. L., Rheault,F., and Fortin,R.

Abstract

The dynamical processes responsible for laser emission in the pulsed pumping of a transversely excited atmospheric (TEA) CO2 laser are investigated. An explanation for the formation of the giant pulse is proposed on the basis of a gain-switching mechanism in which it is assumed that with short strong-current pulses a high population inversion can be achieved prior to the onset of laser action. The kinetics of the mechanism are described by means of a set of nonlinear rate equations idealized to a four-energy-state system. With suitable initial conditions on the populations, the transient solution of these equations for the mixtures CO2-He and CO2-He appears to be consistent with the major features of experimental observation. (Author), Summary in French. Revision of report dated 14 Mar 72.

Published
1972

21. Selection of a Single Pulse from a Mode-Locked TEA CO2 Laser

Author

DEFENCE RESEARCH ESTABLISHMENT VALCARTIER QUEBEC, Rheault,F., Lachambre,J. L., Gilbert,J., Fortin,R., Blanchard,M., DEFENCE RESEARCH ESTABLISHMENT VALCARTIER QUEBEC, Rheault,F., Lachambre,J. L., Gilbert,J., Fortin,R., and Blanchard,M.

Abstract

The isolation of a single pulse from a transversely excited atmospheric (TEA) CO2 laser, actively mode-locked by an acoustic loss modulator, is described. The single pulse selection has been achieved with the aid of a GaAs electrooptic shutter located either inside or outside the laser resonator. Pulses of MW peak power and 2 ns duration have been recorded with instrument-limited precision. The availability of such pulses uncovers new possibilities for the investigation of laser matter interactions at 10.6 micrometers. (Author)

Published
1972

22. Double-Discharge TEA Laser Beams

Author

DEFENCE RESEARCH ESTABLISHMENT VALCARTIER QUEBEC, Fortin,R., Laflamme,A. K., Rheault,F., DEFENCE RESEARCH ESTABLISHMENT VALCARTIER QUEBEC, Fortin,R., Laflamme,A. K., and Rheault,F.

Abstract

The energy and power density distributions of a multi-transverse-mode laser beam are predicted from a simple theoretical model. The corresponding experimental verifications show a good agreement for both the near- and far-field behavior of these beams. Finally, a method for optimizing the peak power density in the focal volume of a converging element is suggested. (Author)

Published
1971

31. Associations Between Buprenorphine\Naloxone and Methadone Treatment and non-Opioid Substance Use in Prescription-Type Opioid Use Disorder: Secondary Analyses From the OPTIMA Study: Associations entre le traitement avec la buprénorphine/naloxone et avec la méthadone et l'utilisation de substances non opioïdes dans le trouble lié à l'usage d'opioïdes de type sur ordonnance : analyses secondaires de l'étude OPTIMA.

Author

Bakouni H, Sharafi H, Drouin S, Fortin R, Marsan S, Brissette S, Socias ME, Le Foll B, Lim R, and Jutras-Aswad D

Subjects
Humans, Analgesics, Opioid therapeutic use, Narcotic Antagonists therapeutic use, Opiate Substitution Treatment, Canada epidemiology, Buprenorphine, Naloxone Drug Combination therapeutic use, Benzodiazepines therapeutic use, Prescriptions, Methadone therapeutic use, Opioid-Related Disorders drug therapy
Abstract

Objectives: There is limited evidence on how opioid agonist treatment (OAT) may affect psychoactive non-opioid substance use in prescription-type opioid use disorder (POUD) and whether this effect might explain OAT outcomes. We aimed to assess the effect of methadone on non-opioid substance use compared to buprenorphine/naloxone (BUP/NX), to explore whether non-opioid substance use is associated with opioid use and retention in treatment, and to test non-opioid use as a moderator of associations between methadone with retention in OAT and opioid use compared to BUP/NX., Methods: This is a secondary analysis of data from the OPTIMA trial, an open-label, pragmatic, parallel, two-arm, pan-Canadian, multicentre, randomized-controlled trial to compare standard methadone model of care and flexible take-home dosing BUP/NX for POUD treatment. We studied the effect of methadone and BUP/NX on non-opioid substance use evaluated by urine drug screen (UDS) and by classes of non-opioid substances (i.e., tetrahydrocannabinol [THC], benzodiazepines, stimulants) (weeks 2-24) using adjusted generalized estimation equation (GEE). We studied the association between non-opioid substance-positive UDS and opioid-positive UDS and retention in treatment, using adjusted GEE and logistic regressions., Results: Overall, methadone was not associated with non-opioid substance-positive UDS compared to BUP/NX (OR: 0.78; 95%CI, 0.41 to 1.48). When non-opioid substances were studied separately, methadone was associated with lower odds of benzodiazepine-positive UDS (OR: 0.63; 95% CI: 0.40 to 0.98) and THC-positive UDS (OR: 0.47; 95% CI: 0.28 to 0.77), but not with different odds of stimulant-positive UDS (OR: 1.29; 95% CI: 0.78 to 2.16) compared to BUP/NX. Substance-positive UDS, overall and separate classes, were not associated with opioid-positive UDS or retention in treatment., Conclusion: Methadone did not show a significant effect on overall non-opioid substance use in POUD compared to BUP/NX treatment but was associated with lower odds of benzodiazepine and THC use in particular. Non-opioid substance use did not predict OAT outcomes. Further research is needed to ascertain whether specific patterns of polysubstance use (quantity and frequency) may affect treatment outcomes., Competing Interests: Declaration of Conflicting InterestsThe authors declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: DJ-A receives study material from Cardiol Therapeutics and Exka for trials funded by public funding bodies. BLF has obtained funding from Pfizer Inc. (GRAND Awards, including salary support) for investigator-initiated projects. He has obtained funding from Indivior for a clinical trial sponsored by Indivior. He has in-kind donations of cannabis products from Aurora Cannabis Enterprises Inc. and study medication donations from Pfizer Inc. (varenicline for smoking cessation) and Bioprojet Pharma. He was also provided a coil for a Transcranial magnetic stimulation (TMS) study from Brainsway. He has obtained industry funding from Canopy Growth Corporation (through research grants handled by the Centre for Addiction and Mental Health and the University of Toronto), Bioprojet Pharma, Alcohol Countermeasure Systems (ACS), Alkermes and Universal Ibogaine. He has received in-kind donations of nabiximols from GW Pharmaceuticals for past studies funded by CIHR and the National Institutes of Health (NIH). He has participated in a session of a National Advisory Board Meeting (Emerging Trends BUP-XR) for Indivior Canada and has been consultant for Shinogi. MES has received partial support from Indivior's Investigator Initiated Study programme for work outside this study. SM has participated in a session of a national advisory board meeting for Indivior Canada as well as for Abbvie Canada.The OPTIMA clinical trial was registered on clinicaltrials.gov before the enrollment of the first participant (NCT03033732).

Published
2024
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32. Spatial deconvolution of aerial radiometric survey and its application to the fallout from a radiological dispersal device.

Author

Sinclair LE and Fortin R

Subjects
Radioactive Fallout statistics & numerical data, Radioactive Hazard Release, Nuclear Weapons, Radiation Monitoring methods, Radioactive Fallout analysis
Abstract

Mapping radioactive contamination using aerial survey measurements is an area under active investigation today. The radiometric aerial survey technique has been extensively applied following reactor accidents and also would provide a key tool for response to a malicious radiological or nuclear incident. Methods exist to calibrate the aerial survey system for quantification of the concentration of natural radionuclides, which can provide guidance. However, these methods have anticipated a spatial distribution of the source which is large in comparison to the survey altitude. In rapid emergency-response aerial surveys of areas of safety concern, deposits of relatively small spatial extent may be expected. The activity of such spatially restricted hot spots is underestimated using the traditional methods. We present here a spatial deconvolution method which can recover some of the variation smoothed out by the averaging due to survey at altitude. We show that the method can recover the true spatial distribution of concentration of a synthetic source. We then apply the method to real aerial survey data collected following detonation of a radiological dispersal device. The findings and implications of the deconvolution are then discussed by reference to a groundbased truckborne survey over the same contamination., (Crown Copyright © 2018. Published by Elsevier Ltd. All rights reserved.)

Published
2019
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34. Aging Reduces the Activation of the mTORC1 Pathway after Resistance Exercise and Protein Intake in Human Skeletal Muscle: Potential Role of REDD1 and Impaired Anabolic Sensitivity.

Author

Francaux M, Demeulder B, Naslain D, Fortin R, Lutz O, Caty G, and Deldicque L

Subjects
AMP-Activated Protein Kinases metabolism, Aged, Anabolic Agents metabolism, Fasting metabolism, Humans, Insulin blood, Mechanistic Target of Rapamycin Complex 1, Phosphorylation, Proto-Oncogene Proteins c-akt metabolism, Resistance Training, Signal Transduction, Transcription Factors metabolism, Young Adult, Aging metabolism, Exercise physiology, Multiprotein Complexes metabolism, Quadriceps Muscle metabolism, TOR Serine-Threonine Kinases metabolism, Whey Proteins administration & dosage
Abstract

This study was designed to better understand the molecular mechanisms involved in the anabolic resistance observed in elderly people. Nine young (22 ± 0.1 years) and 10 older (69 ± 1.7 years) volunteers performed a one-leg extension exercise consisting of 10 × 10 repetitions at 70% of their 3-RM, immediately after which they ingested 30 g of whey protein. Muscle biopsies were taken from the vastus lateralis at rest in the fasted state and 30 min after protein ingestion in the non-exercised (Pro) and exercised (Pro+ex) legs. Plasma insulin levels were determined at the same time points. No age difference was measured in fasting insulin levels but the older subjects had a 50% higher concentration than the young subjects in the fed state (p < 0.05). While no difference was observed in the fasted state, in response to exercise and protein ingestion, the phosphorylation state of PKB (p < 0.05 in Pro and Pro+ex) and S6K1 (p = 0.059 in Pro; p = 0.066 in Pro+ex) was lower in the older subjects compared with the young subjects. After Pro+ex, REDD1 expression tended to be higher (p = 0.087) in the older group while AMPK phosphorylation was not modified by any condition. In conclusion, we show that the activation of the mTORC1 pathway is reduced in skeletal muscle of older subjects after resistance exercise and protein ingestion compared with young subjects, which could be partially due to an increased expression of REDD1 and an impaired anabolic sensitivity.

Published
2016
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35. Strengthening chronic disease prevention programming: the Toward Evidence-Informed Practice (TEIP) Program Evidence Tool.

Author

Albert D, Fortin R, Herrera C, Riley B, Hanning R, Lessio A, and Rush B

Subjects
Health Promotion, Humans, Chronic Disease prevention & control, Evidence-Based Practice standards, Program Evaluation
Abstract

In public health and chronic disease prevention there is increasing priority for effective use of evidence in practice. In Ontario, Canada, despite various models being advanced, public health practitioners are seeking ways to identify and apply evidence in their work in practical and meaningful ways. In a companion article, "Strengthening Chronic Disease Prevention Programming: The Toward Evidence-Informed Practice (TEIP) Program Assessment Tool," we describe use of a tool to assess and strengthen program planning and implementation processes using 19 criteria derived from best and promising practices literature. In this article, we describe use of a complementary Program Evidence Tool to identify, synthesize, and apply a range of evidence sources to strengthen the content of chronic disease prevention programming.The Program Evidence Tool adapts tools of evidence-based medicine to the unique contexts of community-based health promotion and chronic disease prevention. Knowledge management tools and a guided dialogue process known as an Evidence Forum enable community stakeholders to make appropriate use of evidence in diverse social, political, and structural contexts. Practical guidelines and worksheets direct users through 5 steps: 1) define an evidence question, 2) develop a search strategy, 3) collect and synthesize evidence, 4) interpret and adapt evidence, and 5) implement and evaluate. We describe the Program Evidence Tool's benefits, strengths, challenges, and what was learned from its application in 4 Ontario public health departments. The Program Evidence Tool contributes to the development and understanding of the complex use of evidence in community-based chronic disease prevention.

Published
2013
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36. Strengthening chronic disease prevention programming: the Toward Evidence-Informed Practice (TEIP) Program Assessment Tool.

Author

Albert D, Fortin R, Lessio A, Herrera C, Riley B, Hanning R, and Rush B

Subjects
Benchmarking, Evidence-Based Practice, Government Programs, Humans, Public Health Practice, Chronic Disease prevention & control, Program Evaluation
Abstract

Best practices identified solely on the strength of research evidence may not be entirely relevant or practical for use in community-based public health and the practice of chronic disease prevention. Aiming to bridge the gap between best practices literature and local knowledge and expertise, the Ontario Public Health Association, through the Toward Evidence-Informed Practice initiative, developed a set of resources to strengthen evidence-informed decision making in chronic disease prevention programs. A Program Assessment Tool, described in this article, emphasizes better processes by incorporating review criteria into the program planning and implementation process. In a companion paper, "Strengthening Chronic Disease Prevention Programming: The Toward Evidence-Informed Practice (TEIP) Program Evidence Tool," we describe another tool, which emphasizes better evidence by providing guidelines and worksheets to identify, synthesize, and incorporate evidence from a range of sources (eg, peer-reviewed literature, gray literature, local expertise) to strengthen local programs.The Program Assessment Tool uses 19 criteria derived from literature on best and promising practices to assess and strengthen program planning and implementation. We describe the benefits, strengths, and challenges in implementing the tool in 22 community-based chronic disease prevention projects in Ontario, Canada. The Program Assessment Tool helps put best processes into operation to complement adoption and adaptation of evidence-informed practices for chronic disease prevention.

Published
2013
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37. The prodrug activator EtaA from Mycobacterium tuberculosis is a Baeyer-Villiger monooxygenase.

Author

Fraaije MW, Kamerbeek NM, Heidekamp AJ, Fortin R, and Janssen DB

Subjects
Acetone chemistry, Amino Acid Motifs, Antitubercular Agents pharmacology, Catalysis, Dose-Response Relationship, Drug, Esters chemistry, Ketones chemistry, Kinetics, Lactones, Models, Chemical, Oxidation-Reduction, Oxygen metabolism, Oxygenases isolation & purification, Protein Binding, Recombinant Proteins chemistry, Serum Albumin metabolism, Spectrophotometry, Time Factors, Acetone analogs & derivatives, Bacterial Proteins, Ethionamide pharmacology, Mycobacterium tuberculosis metabolism, Oxygenases chemistry, Oxygenases physiology, Prodrugs chemistry
Abstract

EtaA is a newly identified FAD-containing monooxygenase that is responsible for activation of several thioamide prodrugs in Mycobacterium tuberculosis. It was found that purified EtaA displays a remarkably low activity with the antitubercular prodrug ethionamide. Hinted by the presence of a Baeyer-Villiger monooxygenase sequence motif in the EtaA sequence, we have been able to identify a large number of novel EtaA substrates. It was discovered that the enzyme converts a wide range of ketones to the corresponding esters or lactones via a Baeyer-Villiger reaction, indicating that EtaA represents a Baeyer-Villiger monooxygenase. With the exception of aromatic ketones (phenylacetone and benzylacetone), long-chain ketones (e.g. 2-hexanone and 2-dodecanone) also are converted. EtaA is also able to catalyze enantioselective sulfoxidation of methyl-p-tolylsulfide. Conversion of all of the identified substrates is relatively slow with typical k(cat) values of around 0.02 s(-1). The best substrate identified so far is phenylacetone (K(m) = 61 microM, k(cat) = 0.017 s(-1)). Redox monitoring of the flavin cofactor during turnover of phenylacetone indicates that a step in the reductive half-reaction is limiting the rate of catalysis. Intriguingly, EtaA activity could be increased by one order of magnitude by adding bovine serum albumin. This reactivity and substrate acceptance-profiling study provides valuable information concerning this newly identified prodrug activator from M. tuberculosis.

Published
2004
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38. Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia.

Author

Valentini G, Chiarelli LR, Fortin R, Dolzan M, Galizzi A, Abraham DJ, Wang C, Bianchi P, Zanella A, and Mattevi A

Subjects
Allosteric Regulation, Anemia, Hemolytic, Congenital Nonspherocytic genetics, Catalytic Domain, Crystallography, Humans, Mutagenesis, Protein Conformation, Pyruvate Kinase physiology, Structure-Activity Relationship, Erythrocytes enzymology, Pyruvate Kinase chemistry
Abstract

Deficiency of human erythrocyte isozyme (RPK) is, together with glucose-6-phosphate dehydrogenase deficiency, the most common cause of the nonspherocytic hemolytic anemia. To provide a molecular framework to the disease, we have solved the 2.7 A resolution crystal structure of human RPK in complex with fructose 1,6-bisphosphate, the allosteric activator, and phosphoglycolate, a substrate analogue, and we have functionally and structurally characterized eight mutants (G332S, G364D, T384M, D390N, R479H, R486W, R504L, and R532W) found in RPK-deficient patients. The mutations target distinct regions of RPK structure, including domain interfaces and catalytic and allosteric sites. The mutations affect to a different extent thermostability, catalytic efficiency, and regulatory properties. These studies are the first to correlate the clinical symptoms with the molecular properties of the mutant enzymes. Mutations greatly impairing thermostability and/or activity are associated with severe anemia. Some mutant proteins exhibit moderate changes in the kinetic parameters, which are sufficient to cause mild to severe anemia, underlining the crucial role of RPK for erythrocyte metabolism. Prediction of the effects of mutations is difficult because there is no relation between the nature and location of the replaced amino acid and the type of molecular perturbation. Characterization of mutant proteins may serve as a valuable tool to assist with diagnosis and genetic counseling.

Published
2002
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39. The allosteric regulation of pyruvate kinase.

Author

Valentini G, Chiarelli L, Fortin R, Speranza ML, Galizzi A, and Mattevi A

Subjects
Arginine metabolism, Aspartic Acid metabolism, Crystallography, X-Ray, Escherichia coli enzymology, Humans, Kinetics, Models, Molecular, Molecular Sequence Data, Mutagenesis, Site-Directed, Protein Conformation, Pyruvate Kinase metabolism, Pyruvate Kinase genetics
Abstract

Pyruvate kinase (PK) is critical for the regulation of the glycolytic pathway. The regulatory properties of Escherichia coli were investigated by mutating six charged residues involved in interdomain salt bridges (Arg(271), Arg(292), Asp(297), and Lys(413)) and in the binding of the allosteric activator (Lys(382) and Arg(431)). Arg(271) and Lys(413) are located at the interface between A and C domains within one subunit. The R271L and K413Q mutant enzymes exhibit altered kinetic properties. In K413Q, there is partial enzyme activation, whereas R271L is characterized by a bias toward the T-state in the allosteric equilibrium. In the T-state, Arg(292) and Asp(297) form an intersubunit salt bridge. The mutants R292D and D297R are totally inactive. The crystal structure of R292D reveals that the mutant enzyme retains the T-state quaternary structure. However, the mutation induces a reorganization of the interface with the creation of a network of interactions similar to that observed in the crystal structures of R-state yeast and M1 PK proteins. Furthermore, in the R292D structure, two loops that are part of the active site are disordered. The K382Q and R431E mutations were designed to probe the binding site for fructose 1, 6-bisphosphate, the allosteric activator. R431E exhibits only slight changes in the regulatory properties. Conversely, K382Q displays a highly altered responsiveness to the activator, suggesting that Lys(382) is involved in both activator binding and allosteric transition mechanism. Taken together, these results support the notion that domain interfaces are critical for the allosteric transition. They couple changes in the tertiary and quaternary structures to alterations in the geometry of the fructose 1, 6-bisphosphate and substrate binding sites. These site-directed mutagenesis data are discussed in the light of the molecular basis for the hereditary nonspherocytic hemolytic anemia, which is caused by mutations in human erythrocyte PK gene.

Published
2000
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40. Identification and isolation of a membrane protein necessary for leukotriene production.

Author

Miller DK, Gillard JW, Vickers PJ, Sadowski S, Léveillé C, Mancini JA, Charleson P, Dixon RA, Ford-Hutchinson AW, and Fortin R

Subjects
Amino Acid Sequence, Animals, Azides metabolism, Electrophoresis, Polyacrylamide Gel, Humans, Indoles metabolism, Inflammation, Kinetics, Leukotriene Antagonists, Membrane Proteins isolation & purification, Molecular Sequence Data, Molecular Weight, Rats, Affinity Labels metabolism, Indoles pharmacology, Leukotrienes biosynthesis, Membrane Proteins blood, Neutrophils metabolism
Abstract

Several inflammatory diseases, including asthma, arthritis and psoriasis are associated with the production of leukotrienes by neutrophils, mast cells and macrophages. The initial enzymatic step in the formation of leukotrienes is the oxidation of arachidonic acid by 5-lipoxygenase (5-LO) to leukotriene A4. Osteosarcoma cells transfected with 5-LO express active enzyme in broken cell preparations, but no leukotriene metabolites are produced by these cells when stimulated with the calcium ionophore A23187, indicating that an additional component is necessary for cellular 5-LO activity. A new class of indole leukotriene inhibitor has been described that inhibits the formation of cellular leukotrienes but has no direct inhibitory effect on soluble 5-LO activity. We have now used these potent agents to identify and isolate a novel membrane protein of relative molecular mass 18,000 which is necessary for cellular leukotriene synthesis.

Published
1990
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41. Sensitivity to "atypical" mycobacteria in high school children in two community health departments.

Author

Frappier-Davignon L, Fortin R, and Desy M

Subjects
Adolescent, Antigens, Antigens, Bacterial, BCG Vaccine, Cross-Sectional Studies, Female, Humans, Male, Mycobacterium tuberculosis immunology, Nontuberculous Mycobacteria immunology, Quebec epidemiology, Mycobacterium Infections epidemiology, Mycobacterium Infections, Nontuberculous epidemiology, Tuberculin Test standards
Abstract

To evaluate the prevalence of atypical mycobacteria infections in our population, a study was done among students of secondary fifth grade (15-19 years of age) in the community health departments of Maisonneuve-Rosemont in Montreal and of Sherbrooke. The tuberculin used was the RT-23 2 T.U. with Tween 80 and the sensitins prepared by the Statens Serum Institute of Copenhagen from Mycobacterium intracellulare (Battey) and from Mycobacterium kansasii. Each student had a tuberculin test on one arm and a sensitin test on the other. The sensitins were randomly allocated. Depending on how the prevalence is calculated, the Mycobacterium intracellulare infection varies from 3 to 20% in Montreal and from 0 to 9.6% in Sherbrooke. The Mycobacterium kansasii infection is much less important in both regions. All reactions to those atypical mycobacteria are in the range of tuberculin reactions of 0 to 9 mm. In our population which is weakly infected with atypical mycobacteria, the level of positivity of tuberculin reactions to 2 T.U. RT-23 or 5 T.U. P.P.D. would give a more realistic evaluation of M. tuberculosis infection if it was fixed at 5 mm than at 10 mm as it is now.

Published
1989

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