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1. Outcomes of mechanical thrombectomy in anticoagulated patients with acute distal and medium vessel stroke

Author

Salim, Hamza, primary, Musmar, Basel, additional, Adeeb, Nimer, additional, Yedavalli, Vivek, additional, Lakhani, Dhairya, additional, Grewal, Sahibjot Singh, additional, El Naamani, Kareem, additional, Henninger, Nils, additional, Sundararajan, Sri Hari, additional, Kühn, Anna Luisa, additional, Khalife, Jane, additional, Ghozy, Sherief, additional, Scarcia, Luca, additional, Tan, Benjamin YQ, additional, Regenhardt, Robert W, additional, Heit, Jeremy J, additional, Cancelliere, Nicole M, additional, Bernstock, Joshua D, additional, Rouchaud, Aymeric, additional, Fiehler, Jens, additional, Sheth, Sunil, additional, Puri, Ajit S, additional, Dyzmann, Christian, additional, Colasurdo, Marco, additional, Barreau, Xavier, additional, Renieri, Leonardo, additional, Filipe, João Pedro, additional, Harker, Pablo, additional, Radu, Răzvan Alexandru, additional, Abdalkader, Mohamad, additional, Klein, Piers, additional, Marotta, Thomas R, additional, Spears, Julian, additional, Ota, Takahiro, additional, Mowla, Ashkan, additional, Jabbour, Pascal, additional, Biswas, Arundhati, additional, Clarençon, Frédéric, additional, Siegler, James E, additional, Nguyen, Thanh N, additional, Varela, Ricardo, additional, Baker, Amanda, additional, Essibayi, Muhammed Amir, additional, Altschul, David, additional, Gonzalez, Nestor R, additional, Möhlenbruch, Markus A, additional, Costalat, Vincent, additional, Gory, Benjamin, additional, Stracke, Christian Paul, additional, Aziz-Sultan, Mohammad Ali, additional, Hecker, Constantin, additional, Shaikh, Hamza, additional, Liebeskind, David S, additional, Pedicelli, Alessandro, additional, Alexandre, Andrea M, additional, Tancredi, Illario, additional, Faizy, Tobias D, additional, Kalsoum, Erwah, additional, Lubicz, Boris, additional, Patel, Aman B, additional, Pereira, Vitor Mendes, additional, Guenego, Adrien, additional, Dmytriw, Adam A, additional, Amllay, Abdelaziz, additional, Vagal, Achala, additional, ter Schiphorst, Adrien, additional, Thomas, Ajith J., additional, Gopinathan, Anil, additional, Dusart, Anne, additional, Capirossi, Carolina, additional, Mounayer, Charbel, additional, Weyland, Charlotte, additional, Hsieh, Cheng-Yang, additional, Griessenauer, Christoph J., additional, Stapleton, Christopher J., additional, Bellante, Flavio, additional, Marnat, Gaultier, additional, Forestier, Géraud, additional, Cuellar-Saenz, Hugo H., additional, Valente, Iacopo, additional, Sibon, Igor, additional, Rabinov, James D., additional, Berge, Jérôme, additional, Jesser, Jessica, additional, Carlos Martinez-Gutierrez, Juan, additional, Premat, Kevin, additional, Yeo, Leonard LL., additional, Chervak, Lina, additional, Meyer, Lukas, additional, Elhorany, Mahmoud, additional, and Quintero-Consuegra, Miguel, additional

Published
2024
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3. Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal

Author

Dias, Mariana Carvalho, primary, Dos Reis, Ricardo Soares, additional, Santos, João Vasco, additional, Nunes, Ana Paiva, additional, Ferreira, Patricia, additional, Maia, Bruno, additional, Fragata, Isabel, additional, Reis, Joao, additional, Lopes, Joana Ramos, additional, Cruz, Luis, additional, Santo, Gustavo, additional, Machado, Egidio, additional, Gabriel, Denis, additional, Felgueiras, Rui, additional, Dória, Hugo Mota, additional, Carneiro, Angelo, additional, Correia, Manuel, additional, Veloso, Luis Miguel, additional, Barros, Pedro, additional, Gregorio, Tiago, additional, Carvalho, Andreia, additional, Ribeiro, Manuel, additional, Teotonio, Pedro, additional, Neto, Lia, additional, E Melo, Teresa Pinho, additional, Canhao, Patricia, additional, Filipe, João Pedro, additional, Moreira, Goreti, additional, Azevedo, Elsa, additional, Silva, Maria Luis, additional, Costa, Elisa Campos, additional, Oliveira, Guilherme, additional, Pereira, Liliana, additional, Neves, Ligia, additional, Rodrigues, Miguel, additional, Marto, João Pedro, additional, Calado, Sofia, additional, Grenho, Fatima, additional, Branco, Gabriel, additional, Baptista, Tiago, additional, Rocha, Jaime, additional, Ferreira, Carla, additional, Pinho, Joao, additional, Amorim, José Manuel, additional, Araujo, José Manuel, additional, Neiva, Rui Manuel, additional, Viana, João, additional, Lobo, Mariana, additional, Freitas, Alberto, additional, Cruz, Vitor Tedim, additional, Sargento-Freitas, João, additional, and Lopes, José Castro, additional

Published
2022
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5. Performance Evaluation of Low Complexity Massive MIMO Techniques for SC-FDE Schemes

Author

Filipe, João Pedro Matias, Dinis, Rui, and Zazo Bello, Santiago

Subjects
Energy efficiency, Low resolution ADCs, Engenharia e Tecnologia::Engenharia Eletrotécnica, Eletrónica e Informática [Domínio/Área Científica], Massive MIMO, SC-FDE, 5G, Computer Science::Information Theory, Low complexity equalizers
Abstract

Massive-MIMO technology has emerged as a means to achieve 5G's ambitious goals; mainly to obtain higher capacities and excellent performances without requiring the use of more spectrum. In this thesis, focused on the uplink direction, we make a study of performance of low complexity equalization techniques as well as we also approach the impact of the non-linear elements located on the receivers of a system of this type. For that purpose, we consider a multi-user uplink scenario through the Single Carrier with Frequency Domain Equalization (SC-FDE) scheme. This seems to be the most appropriate due to the low energy consumption that it implies, as well as being less favorable to the detrimental effects of high envelope fluctuations, that is, by have a low Peak to Average Power Ratio (PAPR) comparing to other similar modulations, such as the Orthogonal Frequency Division Multiplexing (OFDM). Due to the greater number of antennas and consequent implementation complexity, the equalization processes for Massive- MIMO schemes are aspects that should be simplified, that is, they should avoid the inversion of matrices, contrary to common 4G, with the Zero Forcing (ZF) and Minimum Mean Square Error (MMSE) techniques. To this end, we use low-complexity techniques, such as the Equal Gain Combining (EGC) and the Maximum Ratio Combining (MRC). Since these algorithms are not sufficiently capable of removing the entire Inter-Symbol Interference (ISI) and Inter-User Interference (IUI), we combine them with iterative techniques, namely with the Iterative Block with Decision Feedback Equalizer (IB-DFE) to completely remove the residual ISI and IUI. We also take into account the hardware used in the receivers, since the effects of non-linear distortion can impact negatively the performance of the system. It is expected a strong performance degradation associated to the high quantization noise levels when implementing low-resolution Analog to Digital Converters (ADCs). However, despite these elements with these configurations become harmful to the performance of the majority of the systems, they are considered a desirable solution for Massive-MIMO scenarios, because they make their implementation cheaper and more energy efficient. In this way, we made a study of the impact in the performance by the low-resolution ADCs. In this thesis we suggest that it is possible to bypass these negative effects by implementing a number of receiving antennas far superior to the number of transmitting antennas.

Published
2018

6. Recapitalization of Caixa Geral de Depósitos

Author

Filipe, João Pedro Marquez and Pinho, Paulo

Subjects
Basel, Banking, Ciências Sociais::Economia e Gestão [Domínio/Área Científica], Regulation, Contingent capital
Abstract

This thesis presents a case study about the 2017 recapitalization of Portuguese bank Caixa Geral de Depósitos (CGD). The case starts by presenting CGD’s situation and what led to its urgent capital needs. Furthermore, the case presents an analysis of new capital regulations coming out of Basel III and how banks use a combination of hybrid securities such as Contingent Convertible and Perpetual Notes to comply with such regulations. Finally, there is an in depth analysis of the recent issuance of Additional Tier 1 Capital Write Down Notes by CGD, and what it represents to the state owned bank’s future

Published
2018

7. Endovascular therapy versus medical management in isolated posterior cerebral artery acute ischemic stroke: A multinational multicenter propensity score-weighted study

Author

Salim, Hamza Adel, Pulli, Benjamin, Yedavalli, Vivek, Musmar, Basel, Adeeb, Nimer, Lakhani, Dhairya, Essibayi, Muhammed Amir, El Naamani, Kareem, Henninger, Nils, Sundararajan, Sri Hari, Kühn, Anna Luisa, Khalife, Jane, Ghozy, Sherief, Scarcia, Luca, Grewal, Inayat, Tan, Benjamin YQ, Regenhardt, Robert W, Heit, Jeremy J, Cancelliere, Nicole M, Bernstock, Joshua D, Rouchaud, Aymeric, Fiehler, Jens, Sheth, Sunil, Puri, Ajit S, Dyzmann, Christian, Colasurdo, Marco, Barreau, Xavier, Renieri, Leonardo, Filipe, João Pedro, Harker, Pablo, Radu, Răzvan Alexandru, Abdalkader, Mohamad, Klein, Piers, Marotta, Thomas R, Spears, Julian, Ota, Takahiro, Mowla, Ashkan, Jabbour, Pascal, Biswas, Arundhati, Clarençon, Frédéric, Siegler, James E, Nguyen, Thanh N, Varela, Ricardo, Baker, Amanda, Altschul, David, Gonzalez, Nestor R, Möhlenbruch, Markus A, Costalat, Vincent, Gory, Benjamin, Stracke, Christian Paul, Aziz-Sultan, Mohammad Ali, Hecker, Constantin, Shaikh, Hamza, Griessenauer, Christoph J, Liebeskind, David S, Pedicelli, Alessandro, Alexandre, Andrea M, Tancredi, Illario, Faizy, Tobias D, Kalsoum, Erwah, Lubicz, Boris, Patel, Aman B, Pereira, Vitor Mendes, Wintermark, Max, Guenego, Adrien, and Dmytriw, Adam A

Abstract

Background: Despite the proven effectiveness of endovascular therapy (EVT) in acute ischemic strokes (AIS) involving anterior circulation large vessel occlusions, isolated posterior cerebral artery (PCA) occlusions (iPCAo) remain underexplored in clinical trials. This study investigates the comparative effectiveness and safety of EVT against medical management (MM) in patients with iPCAo.Methods: This multinational, multicenter propensity score-weighted study analyzed data from the Multicenter Analysis of primary Distal medium vessel occlusions: effect of Mechanical Thrombectomy (MAD-MT) registry, involving 37 centers across North America, Asia, and Europe. We included iPCAo patients treated with either EVT or MM. The primary outcome was the modified Rankin Scale (mRS) at 90 days, with secondary outcomes including functional independence, mortality, and safety profiles such as hemorrhagic complications.Results: A total of 177 patients were analyzed (88 MM and 89 EVT). EVT showed a statistically significant improvement in 90-day mRS scores (OR = 0.55, 95% CI = 0.30–1.00, p= 0.048), functional independence (OR = 2.52, 95% CI = 1.02–6.20, p= 0.045), and a reduction in 90-day mortality (OR = 0.12, 95% CI = 0.03–0.54, p= 0.006) compared to MM. Hemorrhagic complications were not significantly different between the groups.Conclusion: EVT for iPCAo is associated with better neurological outcomes and lower mortality compared to MM, without an increased risk of hemorrhagic complications. Nevertheless, these results should be interpreted with caution due to the study’s observational design. The findings are hypothesis-generating and highlight the need for future randomized controlled trials to confirm these observations and establish definitive treatment guidelines for this patient population.

Published
2024
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8. Predictive value of follow-up infarct volume on functional outcomes in middle cerebral artery M2 segment vessel occlusion stroke treated with mechanical thrombectomy

Author

Yedavalli, Vivek, Salim, Hamza Adel, Musmar, Basel, Adeeb, Nimer, El Naamani, Kareem, Henninger, Nils, Sundararajan, Sri Hari, Kühn, Anna Luisa, Khalife, Jane, Ghozy, Sherief, Scarcia, Luca, Tan, Benjamin YQ, Regenhardt, Robert W, Heit, Jeremy J, Cancelliere, Nicole M, Bernstock, Joshua D, Rouchaud, Aymeric, Fiehler, Jens, Sheth, Sunil, Puri, Ajit S, Dyzmann, Christian, Colasurdo, Marco, Barreau, Xavier, Renieri, Leonardo, Filipe, João Pedro, Harker, Pablo, Radu, Răzvan Alexandru, Abdalkader, Mohamad, Klein, Piers, Marotta, Thomas R, Spears, Julian, Ota, Takahiro, Mowla, Ashkan, Jabbour, Pascal, Biswas, Arundhati, Clarençon, Frédéric, Siegler, James E, Nguyen, Thanh N, Varela, Ricardo, Baker, Amanda, Essibayi, Muhammed Amir, Altschul, David, Gonzalez, Nestor R, Möhlenbruch, Markus A, Costalat, Vincent, Gory, Benjamin, Stracke, Christian Paul, Aziz-Sultan, Mohammad Ali, Hecker, Constantin, Shaikh, Hamza, Liebeskind, David S, Pedicelli, Alessandro, Alexandre, Andrea M, Tancredi, Illario, Faizy, Tobias D, Kalsoum, Erwah, Lubicz, Boris, Patel, Aman B, Pereira, Vitor Mendes, Guenego, Adrien, and Dmytriw, Adam A

Abstract

Background: Medium vessel occlusion (MeVO) strokes, particularly affecting the M2 segment of the middle cerebral artery, represent a critical proportion of acute ischemic strokes, posing significant challenges in management and outcome prediction. The efficacy of mechanical thrombectomy (MT) in MeVO stroke may warrant reliable predictors of functional outcomes. This study aimed to investigate the prognostic value of follow-up infarct volume (FIV) for predicting 90-day functional outcomes in MeVO stroke patients undergoing MT.Methods: This multicenter, retrospective cohort study analyzed data from the Multicenter Analysis of primary Distal medium vessel occlusions: effect of Mechanical Thrombectomy (MAD-MT) registry, covering patients with acute ischemic stroke due to M2 segment occlusion treated with MT. We examined the relationship between 90-day functional outcomes, measured by the modified Rankin Scale (mRS), and follow-up infarct volume (FIV), assessed through CT or MRI within 12–36 h post-MT.Results: Among 130 participants, specific FIV thresholds were identified with high specificity and sensitivity for predicting outcomes. A FIV ⩽5 ml was highly specific for predicting favorable and excellent outcomes. The optimal cut-off for both prognostications was identified at ⩽15 ml by the Youden Index, with significant reductions in the likelihood of favorable outcomes observed above a 40 ml threshold. Receiver Operator Curve (ROC) analyses confirmed FIV as a superior predictor of functional outcomes compared to traditional recanalization scores, such as final modified thrombolysis in cerebral infarction score (mTICI). Multivariable analysis further highlighted the inverse relationship between FIV and positive functional outcomes.Conclusions: FIV within 36 h post-MT serves as a potent predictor of 90-day functional outcomes in patients with M2 segment MeVO strokes. Establishing FIV thresholds may aid in the prognostication of stroke outcomes, suggesting a role for FIV in guiding post intervention treatment decisions and informing clinical practice. Future research should focus on validating these findings across diverse patient populations and exploring the integration of FIV measurements with other clinical and imaging markers to enhance outcome prediction accuracy.

Published
2024
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9. Incidence and clinical outcomes of perforations during mechanical thrombectomy for medium vessel occlusion in acute ischemic stroke: A retrospective, multicenter, and multinational study

Author

Dmytriw, Adam A, Musmar, Basel, Salim, Hamza, Ghozy, Sherief, Siegler, James E, Kobeissi, Hassan, Shaikh, Hamza, Khalife, Jane, Abdalkader, Mohamad, Klein, Piers, Nguyen, Thanh N, Heit, Jeremy J, Regenhardt, Robert W, Cancelliere, Nicole M, Bernstock, Joshua D, Naamani, Kareem El, Amllay, Abdelaziz, Meyer, Lukas, Dusart, Anne, Bellante, Flavio, Forestier, Géraud, Rouchaud, Aymeric, Saleme, Suzana, Mounayer, Charbel, Fiehler, Jens, Kühn, Anna Luisa, Puri, Ajit S, Dyzmann, Christian, Kan, Peter T, Colasurdo, Marco, Marnat, Gaultier, Berge, Jérôme, Barreau, Xavier, Sibon, Igor, Nedelcu, Simona, Henninger, Nils, Marotta, Thomas R, Stapleton, Christopher J, Rabinov, James D, Ota, Takahiro, Dofuku, Shogo, Yeo, Leonard LL, Tan, Benjamin YQ, Gopinathan, Anil, Martinez-Gutierrez, Juan Carlos, Salazar-Marioni, Sergio, Sheth, Sunil, Renieri, Leonardo, Capirossi, Carolina, Mowla, Ashkan, Chervak, Lina, Vagal, Achala, Adeeb, Nimer, Cuellar-Saenz, Hugo H, Tjoumakaris, Stavropoula I, Jabbour, Pascal, Khandelwal, Priyank, Biswas, Arundhati, Clarençon, Frédéric, Elhorany, Mahmoud, Premat, Kevin, Valente, Iacopo, Pedicelli, Alessandro, Filipe, João Pedro, Varela, Ricardo, Quintero-Consuegra, Miguel, Gonzalez, Nestor R, Möhlenbruch, Markus A, Jesser, Jessica, Costalat, Vincent, ter Schiphorst, Adrien, Yedavalli, Vivek, Harker, Pablo, Aziz, Yasmin, Gory, Benjamin, Stracke, Christian Paul, Hecker, Constantin, Kadirvel, Ramanathan, Killer-Oberpfalzer, Monika, Griessenauer, Christoph J, Thomas, Ajith J, Hsieh, Cheng-Yang, Liebeskind, David S, Alexandru Radu, Răzvan, Alexandre, Andrea M, Tancredi, Illario, Faizy, Tobias D, Fahed, Robert, Weyland, Charlotte, Lubicz, Boris, Patel, Aman B, Pereira, Vitor Mendes, and Guenego, Adrien

Abstract

Background: Mechanical thrombectomy (MT) has revolutionized the treatment of acute ischemic stroke (AIS) due to large vessel occlusion (LVO), but its efficacy and safety in medium vessel occlusion (MeVO) remain less explored. This multicenter, retrospective study aims to investigate the incidence and clinical outcomes of vessel perforations (confirmed by extravasation during an angiographic series) during MT for AIS caused by MeVO.Methods: Data were collected from 37 academic centers across North America, Asia, and Europe between September 2017 and July 2021. A total of 1373 AIS patients with MeVO underwent MT. Baseline characteristics, procedural details, and clinical outcomes were analyzed.Results: The incidence of vessel perforation was 4.8% (66/1373). Notably, our analysis indicates variations in perforation rates across different arterial segments: 8.9% in M3 segments, 4.3% in M2 segments, and 8.3% in A2 segments (p= 0.612). Patients with perforation had significantly worse outcomes, with lower rates of favorable angiographic outcomes (TICI 2c-3: 23% vs 58.9%, p< 0.001; TICI 2b-3: 56.5% vs 88.3%, p< 0.001). Functional outcomes were also worse in the perforation group (mRS 0–1 at 3 months: 22.7% vs 36.6%, p= 0.031; mRS 0–2 at 3 months: 28.8% vs 53.9%, p< 0.001). Mortality was higher in the perforation group (30.3% vs 16.8%, p= 0.008).Conclusion: This study reveals that while the occurrence of vessel perforation in MT for AIS due to MeVO is relatively rare, it is associated with poor functional outcomes and higher mortality. The findings highlight the need for increased caution and specialized training in performing MT for MeVO. Further prospective research is required for risk mitigation strategies.

Published
2024
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10. Diffusion-weighted imaging of the liver : value of apparent diffusion coefficient and influence of region of interest

Author

Filipe, João Pedro Dos Santos, Alves, Filipe Caseiro, and Semedo, Luís Curvo

Subjects
Doenças do fígado, Imagem de difusão por ressonância magnética, Ciências Médicas [Domínio/Área Científica], Diagnóstico diferencial
Abstract

Trabalho final de mestrado integrado em Medicina área científica de Imagiologia, apresentado á Faculdade de Medicina da Universidade de Coimbra Purpose: To measure apparent diffusion coefficient (ADC) values of liver parenchyma and focal hepatic lesions (FHL), investigate the utility of ADC for the differential diagnosis of hepatic findings, and determine the influence of region of interest (ROI) characteristics in the overall ADC measurements. Materials and Methods: Ninety-three patients (47 men, 46 women; mean age, 58 years) with at least one FHL ≥ 10 mm, or parenchyma abnormalities, were retrospectively evaluated. Reference standard for diagnosis was obtained from histopathologic data, consensus between imaging methods, follow-up imaging and patient clinical history. A total of 90 lesions were evaluated: 14 hepatocellular carcinomas (HCC), 18 metastases, 10 focal nodular hyperplasias (FNH), 4 adenomas, 30 hemangiomas and 14 cysts. Respiratory-Triggered (RT) DWI was performed using b-values of 50 and 700 s/mm2. ADC was measured in hepatic parenchyma by placing ROIs in four different segments, and in FHL by using three circular 1 cm2 ROIs and one ROI encompassing all lesion volume. Data was statistically compared in SPSS software using the Mann-Whitney and Friedman tests. Wilcoxon test was used to confirm ROI influence and receiver operating characteristic (ROC) curve was analyzed to evaluate the utility of ADC for diagnosis of malignancy. P

Published
2011

11. Mechanical Thrombectomy Versus Intravenous Thrombolysis in Distal Medium Vessel Acute Ischemic Stroke: A Multinational Multicenter Propensity Score-Matched Study.

Author

Salim HA, Yedavalli V, Musmar B, Adeeb N, Essibayi MA, Naamani KE, Henninger N, Sundararajan SH, Kühn AL, Khalife J, Ghozy S, Scarcia L, Tan BYQ, Pulli B, Heit JJ, Regenhardt RW, Cancelliere NM, Bernstock JD, Rouchaud A, Fiehler J, Sheth S, Puri AS, Dyzmann C, Colasurdo M, Barreau X, Renieri L, Filipe JP, Harker P, Radu RA, Marotta TR, Spears J, Ota T, Mowla A, Jabbour P, Biswas A, Clarençon F, Siegler JE, Nguyen TN, Varela R, Baker A, Altschul D, Gonzalez NR, Möhlenbruch MA, Costalat V, Gory B, Stracke CP, Aziz-Sultan MA, Hecker C, Shaikh H, Liebeskind DS, Pedicelli A, Alexandre AM, Tancredi I, Faizy TD, Kalsoum E, Lubicz B, Patel AB, Pereira VM, Guenego A, and Dmytriw AA

Abstract

Background and Purpose: The management of acute ischemic stroke (AIS) due to distal medium vessel occlusion (DMVO) remains uncertain, particularly in comparing the effectiveness of intravenous thrombolysis (IVT) plus mechanical thrombectomy (MT) versus IVT alone. This study aimed to evaluate the safety and efficacy in DMVO patients treated with either MT-IVT or IVT alone., Methods: This multinational study analyzed data from 37 centers across North America, Asia, and Europe. Patients with AIS due to DMVO were included, with data collected from September 2017 to July 2023. The primary outcome was functional independence, with secondary outcomes including mortality and safety measures such as types of intracerebral hemorrhage., Results: The study involved 1,057 patients before matching, and 640 patients post-matching. Functional outcomes at 90 days showed no significant difference between groups in achieving good functional recovery (modified Rankin Scale 0-1 and 0-2), with adjusted odds ratios (OR) of 1.21 (95% confidence interval [CI] 0.81 to 1.79; P=0.35) and 1.00 (95% CI 0.66 to 1.51; P>0.99), respectively. Mortality rates at 90 days were similar between the two groups (OR 0.75, 95% CI 0.44 to 1.29; P=0.30). The incidence of symptomatic intracerebral hemorrhage was comparable, but any type of intracranial hemorrhage was significantly higher in the MT-IVT group (OR 0.43, 95% CI 0.29 to 0.63; P<0.001)., Conclusion: The results of this study indicate that while MT-IVT and IVT alone show similar functional and mortality outcomes in DMVO patients, MT-IVT presents a higher risk of hemorrhagic complications, thus MT-IVT may not routinely offer additional benefits over IVT alone for all DMVO stroke patients. Further prospective randomized trials are needed to identify patient subgroups most likely to benefit from MT-IVT treatment in DMVO.

Published
2024
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