30 results on '"El Aoufy, Khadija"'
Search Results
2. Health Literacy and Self-Care in Patients with Chronic Illness: A Systematic Review and Meta-Analysis Protocol
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Magi, Camilla Elena, primary, Bambi, Stefano, additional, Rasero, Laura, additional, Longobucco, Yari, additional, El Aoufy, Khadija, additional, Amato, Carla, additional, Vellone, Ercole, additional, Bonaccorsi, Guglielmo, additional, Lorini, Chiara, additional, and Iovino, Paolo, additional
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- 2024
- Full Text
- View/download PDF
3. The Rising Challenge of Poor Health Literacy of Patients with Systemic Sclerosis: Preliminary Data Identify Important Unmet Needs in an Italian Cohort
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El Aoufy, Khadija, primary, Melis, Maria Ramona, additional, Iovino, Paolo, additional, Bambi, Stefano, additional, Lorini, Chiara, additional, Bonaccorsi, Guglielmo, additional, Galetti, Ilaria, additional, Garbagnati, Carla, additional, Canziani, Paola, additional, Tonolo, Silvia, additional, Mitola, Marco, additional, Guiducci, Serena, additional, Furst, Daniel E., additional, Matucci-Cerinic, Marco, additional, Rasero, Laura, additional, and Bellando-Randone, Silvia, additional
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- 2024
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- View/download PDF
4. Enhancing the comfort of hospitalized elderly patients: pain management strategies for painful nursing procedures.
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Magi, Camilla Elena, Longobucco, Yari, Amato, Carla, Camedda, Claudia, Balestri, Chiara, El Aoufy, Khadija, Iovino, Paolo, Bambi, Stefano, and Rasero, Laura
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- 2024
- Full Text
- View/download PDF
5. Lymphatic Endothelial-to-Myofibroblast Transition: A Potential New Mechanism Underlying Skin Fibrosis in Systemic Sclerosis
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Rosa, Irene, primary, Romano, Eloisa, additional, Fioretto, Bianca Saveria, additional, El Aoufy, Khadija, additional, Bellando-Randone, Silvia, additional, Matucci-Cerinic, Marco, additional, and Manetti, Mirko, additional
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- 2023
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- View/download PDF
6. Virtual Reality and Augmented Reality Training in Disaster Medicine Courses for Students in Nursing: A Scoping Review of Adoptable Tools
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Magi, Camilla Elena, primary, Bambi, Stefano, additional, Iovino, Paolo, additional, El Aoufy, Khadija, additional, Amato, Carla, additional, Balestri, Chiara, additional, Rasero, Laura, additional, and Longobucco, Yari, additional
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- 2023
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7. The differential crosstalk of the skin-gut microbiome axis as a new emerging actor in systemic sclerosis
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Russo, Edda, primary, Bellando-Randone, Silvia, additional, Carboni, Davide, additional, Fioretto, Bianca Saveria, additional, Romano, Eloisa, additional, Baldi, Simone, additional, El Aoufy, Khadija, additional, Ramazzotti, Matteo, additional, Rosa, Irene, additional, Lepri, Gemma, additional, Di Gloria, Leandro, additional, Pallecchi, Marco, additional, Bruni, Cosimo, additional, Melchiorre, Daniela, additional, Guiducci, Serena, additional, Manetti, Mirko, additional, Bartolucci, Gian Luca, additional, Matucci-Cerinic, Marco, additional, and Amedei, Amedeo, additional
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- 2023
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8. Awake Prone Positioning in Nonintubated Patients With Acute Hypoxemic Respiratory Failure
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Fusi, C, Bulleri, E, Villa, M, Pisani, L, El Aoufy, K, Lucchini, A, Bambi, S, Fusi, Cristian, Bulleri, Enrico, Villa, Michele, Pisani, Luigi, El Aoufy, Khadija, Lucchini, Alberto, Bambi, Stefano, Fusi, C, Bulleri, E, Villa, M, Pisani, L, El Aoufy, K, Lucchini, A, Bambi, S, Fusi, Cristian, Bulleri, Enrico, Villa, Michele, Pisani, Luigi, El Aoufy, Khadija, Lucchini, Alberto, and Bambi, Stefano
- Abstract
Background Awake prone positioning research focuses primarily on improving oxygenation and reducing intubation and mortality rates. Secondary outcomes concerning patient safety have been poorly addressed. Objective To summarize current evidence on the frequency of adverse events during awake prone positioning and the effects on patients’ safety, comfort, and tolerance. Methods This scoping review used the Preferred Reporting Items for Systematic Reviews and Meta-analyses Extension for Scoping Reviews. MEDLINE/PubMed and CINAHL databases were the primary sources for the systematic search. Results The review included 19 original studies involving 949 patients who underwent awake prone positioning. No major complications such as death, severe respiratory compromise, or hemodynamic disease were reported. Ten studies reported the following secondary adverse events related to awake prone positioning: skin breakdown (1%-6% of patients), pain (12%-42%), discomfort (35%-43%), vomiting (2%-7%), intolerance (3%-47%), and vascular catheter dislodgment (5%). The duration of awake prone positioning sessions varied widely (0.3-19 hours). Seven studies reported that nurses helped patients during prone positioning maneuvers, including monitoring and surveillance, and 3 studies reported patients placing themselves in the prone position. In 6 studies light or moderate sedation was employed in the procedures. Conclusions Awake prone positioning was not related to cardiorespiratory consequences but was associated with pain, intolerance, discomfort, and patients’ refusal. Patients should receive education regarding awake prone positioning to improve their acceptance. Health care professionals should opti-mize pain control, communication, patient comfort, patient adherence, and correct positioning.
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- 2023
9. The dark side of the CPAP helmet: Why we need more monitoring systems
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Bambi, S, Manici, M, El Aoufy, K, Longobucco, Y, Lucchini, A, Bambi, Stefano, Manici, Matteo, El Aoufy, Khadija, Longobucco, Yari, Lucchini, Alberto, Bambi, S, Manici, M, El Aoufy, K, Longobucco, Y, Lucchini, A, Bambi, Stefano, Manici, Matteo, El Aoufy, Khadija, Longobucco, Yari, and Lucchini, Alberto
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- 2023
10. The Effectiveness of NIV and CPAP Training on the Job in COVID-19 Acute Care Wards: A Nurses' Self-Assessment of Skills
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Bambi, S, Parente, E, Bardacci, Y, Baldassini Rodriguez, S, Forciniti, C, Ballerini, L, Caruso, C, El Aoufy, K, Poggianti, M, Bonacaro, A, Rona, R, Rasero, L, Lucchini, A, Bambi, Stefano, Parente, Eustachio, Bardacci, Yari, Baldassini Rodriguez, Samuele, Forciniti, Carolina, Ballerini, Lorenzo, Caruso, Christian, El Aoufy, Khadija, Poggianti, Marta, Bonacaro, Antonio, Rona, Roberto, Rasero, Laura, Lucchini, Alberto, Bambi, S, Parente, E, Bardacci, Y, Baldassini Rodriguez, S, Forciniti, C, Ballerini, L, Caruso, C, El Aoufy, K, Poggianti, M, Bonacaro, A, Rona, R, Rasero, L, Lucchini, A, Bambi, Stefano, Parente, Eustachio, Bardacci, Yari, Baldassini Rodriguez, Samuele, Forciniti, Carolina, Ballerini, Lorenzo, Caruso, Christian, El Aoufy, Khadija, Poggianti, Marta, Bonacaro, Antonio, Rona, Roberto, Rasero, Laura, and Lucchini, Alberto
- Abstract
Background: Noninvasive ventilation (NIV) in COVID-19 patients outside of intensive care unit (ICU) settings was a feasible support during the pandemic outbreak. The aim of this study was to assess the effectiveness of an “on the job” NIV training program provided to 66 nurses working in 3 COVID-19 wards in an Italian university hospital. Methods: A quasi-experimental longitudinal before–after study was designed. The NIV Team education program, provided by expert ICU nurses, included: 3 h sessions of training on the job during work-shifts about the management of helmet-continuous positive airway pressure (CPAP) Venturi systems, and NIV with oronasal and full-face masks. An eleven-item “brief skills self-report tool” was administered before and after the program to explore the perception of NIV education program attendees about their level of skills. Results: In total, 59 nurses responded to the questionnaire. There was an improvement in the skill levels of the management of Helmet-CPAP (median before training 2, inter-quartile range (IQR) 0–6; median after training 8, IQR 3–9; p < 0.0001), and mask-NIV (median before training 2, IQR 0–6; median after training 8, IQR 3–9; p < 0.0001). Conclusions: Training on the job performed by expert ICU nurses can be a valuable and fast means to implement new Helmet-CPAP and mask-NIV skills outside of ICUs.
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- 2023
11. Sleep Quality and Its Relationship to Anxiety and Hardiness in a Cohort of Frontline Italian Nurses during the First Wave of the COVID-19 Pandemic.
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Baldassini Rodriguez, Samuele, Bardacci, Yari, El Aoufy, Khadija, Bazzini, Marco, Caruso, Christian, Giusti, Gian Domenico, Mezzetti, Andrea, Lucchini, Alberto, Iozzo, Pasquale, Guazzini, Andrea, Magi, Camilla Elena, Iovino, Paolo, Longobucco, Yari, Rasero, Laura, Bambi, Stefano, and Gray, Richard
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MENTAL illness prevention ,PSYCHOLOGICAL resilience ,MENTAL health ,QUESTIONNAIRES ,ANXIETY ,MULTIVARIATE analysis ,DESCRIPTIVE statistics ,SURVEYS ,LONGITUDINAL method ,STATE-Trait Anxiety Inventory ,RESEARCH methodology ,RESEARCH ,SLEEP quality ,CONFIDENCE intervals ,DATA analysis software ,COVID-19 pandemic - Abstract
Introduction: The COVID-19 pandemic has had a considerable impact on the psychological and psychopathological status of the population and health care workers in terms of insomnia, anxiety, depression, and post-traumatic stress disorder. The primary aim of this study was to describe and evaluate the impact of the pandemic on insomnia levels of a cohort of Italian nurses, particularly those involved in the care of COVID-19 patients. The secondary aim was to identify the interaction between insomnia and hardiness, anxiety, and sleep disturbances. Materials and Methods: A descriptive–exploratory study was conducted using an online survey during the first wave of the COVID-19 pandemic (March to July 2020). The questionnaire consisted of multiple-choice, open-ended, closed, and semi-closed questions. The psychometric tools administered were the Dispositional Resilience Scale (DRS-15), the State–Trait Anxiety Inventory (STAI-Y), and the Insomnia Severity Index (ISI). Results: a cohort of 1167 nurses fully completed the questionnaire (86.2% of total respondents). The insomnia scale survey showed an increase in post-pandemic scores compared to those before the pandemic, implying that insomnia levels increased after the first pandemic wave. Insomnia scores were directly correlated with anxiety levels (r = 0.571; p ≤ 0.05) and inversely correlated with hardiness levels (r = −0.324; p < 0.001). Multivariate analysis revealed the following protective factors: not having worked in COVID-19 wards, high levels of hardiness (commitment), and the presence of high pre-pandemic insomnia disorder. The main risk factor for insomnia reported in the analysis was a high anxiety score. Discussion and Conclusion: Anxiety represented the main risk factor for insomnia severity in our sample, while hardiness was confirmed as a protective factor. Thus, it is necessary to design further studies to identify additional risk factors for poor sleep quality and to develop educational courses and strategies aimed at enhancing rest and sleep quality, especially for frontline nurses. [ABSTRACT FROM AUTHOR]
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- 2023
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12. Systemic Sclerosis Patients Experiencing Mindfulness-Based Stress Reduction Program: The Beneficial Effect on Their Psychological Status and Quality of Life
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El Aoufy, Khadija, primary, Pezzutto, Arianna, additional, Pollina, Alessandra, additional, Rasero, Laura, additional, Bambi, Stefano, additional, Bellando-Randone, Silvia, additional, Guiducci, Serena, additional, Maddali-Bongi, Susanna, additional, and Matucci Cerinic, Marco, additional
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- 2023
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13. The Effectiveness of NIV and CPAP Training on the Job in COVID-19 Acute Care Wards: A Nurses’ Self-Assessment of Skills
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Bambi, Stefano, primary, Parente, Eustachio, additional, Bardacci, Yari, additional, Baldassini Rodriguez, Samuele, additional, Forciniti, Carolina, additional, Ballerini, Lorenzo, additional, Caruso, Christian, additional, El Aoufy, Khadija, additional, Poggianti, Marta, additional, Bonacaro, Antonio, additional, Rona, Roberto, additional, Rasero, Laura, additional, and Lucchini, Alberto, additional
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- 2022
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14. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2022 update
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Smolen, Josef S., Landewé, Robert B. M., Bergstra, Sytske Anne, Kerschbaumer, Andreas, Sepriano, Alexandre, Aletaha, Daniel, Caporali, Roberto, Edwards, Christopher John, Hyrich, Kimme L., Pope, Janet E., de Souza, Savia, Stamm, Tanja A., Takeuchi, Tsutomu, Verschueren, Patrick, Winthrop, Kevin L., Balsa, Alejandro, Bathon, Joan M., Buch, Maya H., Burmester, Gerd R., Buttgereit, Frank, Cardiel, Mario Humberto, Chatzidionysiou, Katerina, Codreanu, Catalin, Cutolo, Maurizio, den Broeder, Alfons A., el Aoufy, Khadija, Finckh, Axel, Fonseca, João Eurico, Gottenberg, Jacques-Eric, Haavardsholm, Espen A., Iagnocco, Annamaria, Lauper, Kim, Li, Zhanguo, McInnes, Iain B., Mysler, Eduardo F., Nash, Peter, Poor, Gyula, Ristic, Gorica G., Rivellese, Felice, Rubbert-Roth, Andrea, Schulze-Koops, Hendrik, Stoilov, Nikolay, Strangfeld, Anja, van der Helm-van Mil, Annette, van Duuren, Elsa, Vliet Vlieland, Theodora P. M., Westhovens, René, van der Heijde, D. sirée, Clinical Immunology and Rheumatology, and AII - Inflammatory diseases
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Arthritis, Rheumatoid ,Biological Therapy ,All institutes and research themes of the Radboud University Medical Center ,Rheumatology ,Arthritis ,Rheumatoid ,Antirheumatic Agents ,Immunology ,Inflammatory diseases Radboud Institute for Health Sciences [Radboudumc 5] ,Immunology and Allergy ,General Biochemistry, Genetics and Molecular Biology - Abstract
ObjectivesTo provide an update of the EULAR rheumatoid arthritis (RA) management recommendations addressing the most recent developments in the field.MethodsAn international task force was formed and solicited three systematic literature research activities on safety and efficacy of disease-modifying antirheumatic drugs (DMARDs) and glucocorticoids (GCs). The new evidence was discussed in light of the last update from 2019. A predefined voting process was applied to each overarching principle and recommendation. Levels of evidence and strengths of recommendation were assigned to and participants finally voted on the level of agreement with each item.ResultsThe task force agreed on 5 overarching principles and 11 recommendations concerning use of conventional synthetic (cs) DMARDs (methotrexate (MTX), leflunomide, sulfasalazine); GCs; biological (b) DMARDs (tumour necrosis factor inhibitors (adalimumab, certolizumab pegol, etanercept, golimumab, infliximab including biosimilars), abatacept, rituximab, tocilizumab, sarilumab and targeted synthetic (ts) DMARDs, namely the Janus kinase inhibitors tofacitinib, baricitinib, filgotinib, upadacitinib. Guidance on monotherapy, combination therapy, treatment strategies (treat-to-target) and tapering in sustained clinical remission is provided. Safety aspects, including risk of major cardiovascular events (MACEs) and malignancies, costs and sequencing of b/tsDMARDs were all considered. Initially, MTX plus GCs is recommended and on insufficient response to this therapy within 3–6 months, treatment should be based on stratification according to risk factors; With poor prognostic factors (presence of autoantibodies, high disease activity, early erosions or failure of two csDMARDs), any bDMARD should be added to the csDMARD; after careful consideration of risks of MACEs, malignancies and/or thromboembolic events tsDMARDs may also be considered in this phase. If the first bDMARD (or tsDMARD) fails, any other bDMARD (from another or the same class) or tsDMARD (considering risks) is recommended. With sustained remission, DMARDs may be tapered but should not be stopped. Levels of evidence and levels of agreement were high for most recommendations.ConclusionsThese updated EULAR recommendations provide consensus on RA management including safety, effectiveness and cost.
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- 2023
15. 2022 update
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Smolen, Josef S., Landewé, Robert B.M., Bergstra, Sytske Anne, Kerschbaumer, Andreas, Sepriano, Alexandre, Aletaha, Daniel, Caporali, Roberto, Edwards, Christopher John, Hyrich, Kimme L., Pope, Janet E., De Souza, Savia, Stamm, Tanja A., Takeuchi, Tsutomu, Verschueren, Patrick, Winthrop, Kevin L., Balsa, Alejandro, Bathon, Joan M., Buch, Maya H., Burmester, Gerd R., Buttgereit, Frank, Cardiel, Mario Humberto, Chatzidionysiou, Katerina, Codreanu, Catalin, Cutolo, Maurizio, Den Broeder, Alfons A., El Aoufy, Khadija, Finckh, Axel, Fonseca, João Eurico, Gottenberg, Jacques Eric, Haavardsholm, Espen A., Iagnocco, Annamaria, Lauper, Kim, Li, Zhanguo, McInnes, Iain B., Mysler, Eduardo F., Nash, Peter, Poor, Gyula, Ristic, Gorica G., Rivellese, Felice, Rubbert-Roth, Andrea, Schulze-Koops, Hendrik, Stoilov, Nikolay, Strangfeld, Anja, Van Der Helm-Van Mil, Annette, Van Duuren, Elsa, Vliet Vlieland, Theodora P.M., Westhovens, René, Van Der Heijde, Désirée, NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM), and Comprehensive Health Research Centre (CHRC) - pólo NMS
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Arthritis, Rheumatoid ,Biological Therapy ,Rheumatology ,Biochemistry, Genetics and Molecular Biology(all) ,Antirheumatic Agents ,Immunology ,Immunology and Allergy - Abstract
Funding Information: This study was funded by European League Against Rheumatism. Publisher Copyright: © Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ. Objectives: To provide an update of the EULAR rheumatoid arthritis (RA) management recommendations addressing the most recent developments in the field. Methods: An international task force was formed and solicited three systematic literature research activities on safety and efficacy of disease-modifying antirheumatic drugs (DMARDs) and glucocorticoids (GCs). The new evidence was discussed in light of the last update from 2019. A predefined voting process was applied to each overarching principle and recommendation. Levels of evidence and strengths of recommendation were assigned to and participants finally voted on the level of agreement with each item. Results: The task force agreed on 5 overarching principles and 11 recommendations concerning use of conventional synthetic (cs) DMARDs (methotrexate (MTX), leflunomide, sulfasalazine); GCs; biological (b) DMARDs (tumour necrosis factor inhibitors (adalimumab, certolizumab pegol, etanercept, golimumab, infliximab including biosimilars), abatacept, rituximab, tocilizumab, sarilumab and targeted synthetic (ts) DMARDs, namely the Janus kinase inhibitors tofacitinib, baricitinib, filgotinib, upadacitinib. Guidance on monotherapy, combination therapy, treatment strategies (treat-to-target) and tapering in sustained clinical remission is provided. Safety aspects, including risk of major cardiovascular events (MACEs) and malignancies, costs and sequencing of b/tsDMARDs were all considered. Initially, MTX plus GCs is recommended and on insufficient response to this therapy within 3-6 months, treatment should be based on stratification according to risk factors; With poor prognostic factors (presence of autoantibodies, high disease activity, early erosions or failure of two csDMARDs), any bDMARD should be added to the csDMARD; after careful consideration of risks of MACEs, malignancies and/or thromboembolic events tsDMARDs may also be considered in this phase. If the first bDMARD (or tsDMARD) fails, any other bDMARD (from another or the same class) or tsDMARD (considering risks) is recommended. With sustained remission, DMARDs may be tapered but should not be stopped. Levels of evidence and levels of agreement were high for most recommendations. Conclusions: These updated EULAR recommendations provide consensus on RA management including safety, effectiveness and cost. publishersversion published
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- 2022
16. Oral Care in Intensive Care Unit and Chlorhexidine: An Endless Story
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Bambi, S, El Aoufy, K, Iozzo, P, Negro, A, Bardacci, Y, Rodriguez, S, Giusti, G, Rasero, L, Lucchini, A, Bambi, Stefano, El Aoufy, Khadija, Iozzo, Pasquale, Negro, Alessandra, Bardacci, Yari, Rodriguez, Samuele Baldassini, Giusti, Giandomenico, Rasero, Laura, Lucchini, Alberto, Bambi, S, El Aoufy, K, Iozzo, P, Negro, A, Bardacci, Y, Rodriguez, S, Giusti, G, Rasero, L, Lucchini, A, Bambi, Stefano, El Aoufy, Khadija, Iozzo, Pasquale, Negro, Alessandra, Bardacci, Yari, Rodriguez, Samuele Baldassini, Giusti, Giandomenico, Rasero, Laura, and Lucchini, Alberto
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- 2022
17. The Effectiveness of NIV and CPAP Training on the Job in COVID-19 Acute Care Wards: A Nurses' Self-Assessment of Skills.
- Author
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Bambi, Stefano, Parente, Eustachio, Bardacci, Yari, Baldassini Rodriguez, Samuele, Forciniti, Carolina, Ballerini, Lorenzo, Caruso, Christian, El Aoufy, Khadija, Poggianti, Marta, Bonacaro, Antonio, Rona, Roberto, Rasero, Laura, and Lucchini, Alberto
- Subjects
STATISTICS ,INFERENTIAL statistics ,KRUSKAL-Wallis Test ,NURSING ,COVID-19 ,ACADEMIC medical centers ,CONTINUOUS positive airway pressure ,SELF-evaluation ,RESEARCH methodology ,ARTIFICIAL respiration ,CHI-squared test ,DESCRIPTIVE statistics ,CRITICAL care medicine ,QUESTIONNAIRES ,DATA analysis ,DATA analysis software ,EDUCATIONAL outcomes ,LONGITUDINAL method - Abstract
Background: Noninvasive ventilation (NIV) in COVID-19 patients outside of intensive care unit (ICU) settings was a feasible support during the pandemic outbreak. The aim of this study was to assess the effectiveness of an "on the job" NIV training program provided to 66 nurses working in 3 COVID-19 wards in an Italian university hospital. Methods: A quasi-experimental longitudinal before–after study was designed. The NIV Team education program, provided by expert ICU nurses, included: 3 h sessions of training on the job during work-shifts about the management of helmet-continuous positive airway pressure (CPAP) Venturi systems, and NIV with oronasal and full-face masks. An eleven-item "brief skills self-report tool" was administered before and after the program to explore the perception of NIV education program attendees about their level of skills. Results: In total, 59 nurses responded to the questionnaire. There was an improvement in the skill levels of the management of Helmet-CPAP (median before training 2, inter-quartile range (IQR) 0–6; median after training 8, IQR 3–9; p < 0.0001), and mask-NIV (median before training 2, IQR 0–6; median after training 8, IQR 3–9; p < 0.0001). Conclusions: Training on the job performed by expert ICU nurses can be a valuable and fast means to implement new Helmet-CPAP and mask-NIV skills outside of ICUs. [ABSTRACT FROM AUTHOR]
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- 2023
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18. Regional Citrate Anticoagulation and Systemic Anticoagulation during Pediatric Continuous Renal Replacement Therapy: A Systematic Literature Review
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Buccione, Emanuele, primary, Bambi, Stefano, additional, Rasero, Laura, additional, Tofani, Lorenzo, additional, Piazzini, Tessa, additional, Della Pelle, Carlo, additional, El Aoufy, Khadija, additional, Ricci, Zaccaria, additional, Romagnoli, Stefano, additional, and Villa, Gianluca, additional
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- 2022
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19. Menstruation-Related Disorders—Dysmenorrhea and Heavy Bleeding—as Significant Epiphenomena in Women With Rheumatic Diseases
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Orlandi, Martina, primary, Vannuccini, Silvia, additional, El Aoufy, Khadija, additional, Melis, Maria Ramona, additional, Lepri, Gemma, additional, Sambataro, Gianluca, additional, Bellando-Randone, Silvia, additional, Guiducci, Serena, additional, Cerinic, Marco Matucci, additional, and Petraglia, Felice, additional
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- 2022
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20. Promoting and Risk Factors of Nurses’ Hardiness Levels during the COVID-19 Pandemic: Results from an Italian Cohort
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Baldassini Rodriguez, Samuele, primary, Bardacci, Yari, additional, El Aoufy, Khadija, additional, Bazzini, Marco, additional, Caruso, Christian, additional, Giusti, Gian Domenico, additional, Mezzetti, Andrea, additional, Bambi, Stefano, additional, Guazzini, Andrea, additional, and Rasero, Laura, additional
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- 2022
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21. Lung ultrasound B-lines in systemic sclerosis: cut-off values and methodological indications for interstitial lung disease screening
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Gargani, Luna, primary, Romei, Chiara, additional, Bruni, Cosimo, additional, Lepri, Gemma, additional, El-Aoufy, Khadija, additional, Orlandi, Martina, additional, D’Errico, Luigia, additional, Bandini, Giulia, additional, D’Angelo, Gennaro, additional, Guiducci, Serena, additional, Dagna, Lorenzo, additional, Falaschi, Fabio, additional, Matucci-Cerinic, Marco, additional, and Moggi-Pignone, Alberto, additional
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- 2021
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22. Oral Lactobacillus Species in Systemic Sclerosis
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Melchiorre, Daniela, primary, Ceccherini, Maria Teresa, additional, Romano, Eloisa, additional, Cometi, Laura, additional, El-Aoufy, Khadija, additional, Bellando-Randone, Silvia, additional, Roccotelli, Angela, additional, Bruni, Cosimo, additional, Moggi-Pignone, Alberto, additional, Carboni, Davide, additional, Guiducci, Serena, additional, Lepri, Gemma, additional, Tofani, Lorenzo, additional, Pietramellara, Giacomo, additional, and Matucci-Cerinic, Marco, additional
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- 2021
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23. A Practical Approach to the Management of Digital Ulcers in Patients With Systemic Sclerosis A Narrative Review
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Hughes, Michael, Allanore, Yannick, El Aoufy, Khadija, Denton, Christopher P., Khanna, Dinesh, Krieg, Thomas, Matucci-Cerinic, Marco, Hughes, Michael, Allanore, Yannick, El Aoufy, Khadija, Denton, Christopher P., Khanna, Dinesh, Krieg, Thomas, and Matucci-Cerinic, Marco
- Abstract
IMPORTANCE Digital ulcers (DUs) occurring on the fingers in patients with systemic sclerosis (SSc) are associated with substantial pain and disability and are often challenging to treat. However, careful clinical assessment and prompt intervention (wound bed management and systemic pharmacologic treatment) may modify the clinical course. OBJECTIVES To provide a practical approach to the assessment and management of SSc-DUs and highlight unmet needs and research priorities. EVIDENCE REVIEW A narrative review of the extant literature was undertaken to provide a broad overview of current knowledge and augmented by expert opinion. FINDINGS Half of the patients with SSc have a history of DUs, and there is a point of prevalence of approximately 10%. Digital ulcers are often very painful and affect all aspects of physical, social, and family life as well as occupation. Digital ulcers are associated with a severe disease course. Systemic sclerosis DUs, particularly those occurring on the fingertips, represent a vascular ischemic complication, although other etiopathogenic factors play an important role. To guide management, a structured clinical approach is required, including DU definition, classification, and categorization. Digital ulcers require a multidisciplinary approach with close cooperation between physicians and specialist nursing and other allied health professionals to guarantee the appropriate treatment and provide patient education. Local wound bed management is necessary for all DUs and is combined with systemic (pharmacologic) treatments. When treating a DU, the clinician should actively review the therapeutic strategy to prevent further DUs, including the level of systemic disease control, and monitor closely for the development of DU complications, including infection and progression to gangrene. Despite a wide available therapeutic armory, a number of unmet needs and challenges remain that that require resolution to optimize DU management. CONCLUSIONS AN
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- 2021
24. A Practical Approach to the Management of Digital Ulcers in Patients With Systemic Sclerosis
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Hughes, Michael, Allanore, Yannick, El Aoufy, Khadija, Denton, Christopher P., Khanna, Dinesh, Krieg, Thomas M., Matucci-Cerinic, Marco, Hughes, Michael, Allanore, Yannick, El Aoufy, Khadija, Denton, Christopher P., Khanna, Dinesh, Krieg, Thomas M., and Matucci-Cerinic, Marco
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- 2021
25. Rehabilitation of the face and temporomandibular joint in systemic sclerosis
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Maddali Bongi, Susanna, primary, Passalacqua, Mauro, additional, Landi, Giovanna, additional, Mikhaylova, Svetlana, additional, Tofani, Lorenzo, additional, Del Rosso, Angela, additional, El Aoufy, Khadija, additional, Baccini, Marco, additional, Matucci-Cerinic, Marco, additional, and Melchiorre, Daniela, additional
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- 2021
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26. Patient preferences for systemic sclerosis treatment: A descriptive study within an Italian cohort
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El Aoufy, Khadija, primary, Bruni, Cosimo, additional, Rasero, Laura, additional, Matucci Cerinic, Marco, additional, and Furst, Daniel Eric, additional
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- 2020
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27. Lung ultrasound B-lines in systemic sclerosis: cut-off values and methodological indications for interstitial lung disease screening.
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Gargani, Luna, Romei, Chiara, Bruni, Cosimo, Lepri, Gemma, El-Aoufy, Khadija, Orlandi, Martina, D'Errico, Luigia, Bandini, Giulia, D'Angelo, Gennaro, Guiducci, Serena, Dagna, Lorenzo, Falaschi, Fabio, Matucci-Cerinic, Marco, and Moggi-Pignone, Alberto
- Subjects
REFERENCE values ,CYTOKINES ,AUTOANTIBODIES ,PREDICTIVE tests ,INTERSTITIAL lung diseases ,MEDICAL screening ,SYSTEMIC scleroderma ,DESCRIPTIVE statistics ,COMPUTED tomography ,SENSITIVITY & specificity (Statistics) - Abstract
Objectives Lung ultrasound (LUS), through assessment of B-lines and pleural line alterations, is able to evaluate interstitial lung disease (ILD), a frequent complication of SSc. Different scanning schemes and counting methods have been proposed but no clear cut-off values have been indicated for screening. We aimed to evaluate the accuracy of different LUS methodological approaches to detect ILD compared with high-resolution CT (HRCT) as the gold standard. Methods Sixty-nine SSc patients underwent LUS and chest HRCT on the same day. Both exams were scored by expert readers. The accuracy of different scanning schemes and counting methods was assessed and clinical and functional data were compared with imaging findings. Results B-lines were more numerous in patients with the diffuse skin subset and Scl70 autoantibody positivity. The number of B-lines correlated with the Scleroderma Lung Study (SLS) I HRCT score (R = 0.754, P < 0.0001). A total of >10 B-lines on the whole chest or >1 B-line on the postero-basal chest showed 97% sensitivity for detecting even very early ILD signs (corresponding to an SLS I score of 1). Sensitivity increased to 100% when pleural line alterations were included in the analysis. Conclusions LUS has a very high sensitivity in detecting SSc-related ILD. A cut-off value of >10 B-lines on the whole chest or >1 B-line on the postero-basal chest can be used for the screening of SSc-ILD. Assessing only the postero-basal chest seems to be mostly effective, combining high sensitivity with a less time-consuming approach. [ABSTRACT FROM AUTHOR]
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- 2022
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28. Patient preferences for systemic sclerosis treatment: A descriptive study within an Italian cohort
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El Aoufy, Khadija, Bruni, Cosimo, Rasero, Laura, Matucci Cerinic, Marco, and Furst, Daniel Eric
- Abstract
Objectives: The aim of this study is to ascertain systemic sclerosis patients’ preferences regarding the formulations of the medications they use.Methods: We undertook questionnaires and interviews aimed at understanding systemic sclerosis patients’ preferences with respect to the medications they used.Results: Among 160 systemic sclerosis patients, we found that the majority does not have difficulty taking their medication. However, preferences were identified (81.25% – 65/80 – preferred oral meds and 47.50% – 38/80 – disliked rectal/vaginal meds), as well as some systemic sclerosis patients have significant difficulties using their medications. In fact, factors such as swallowing and fine finger motion difficulties were frequent, while intravenous/intramuscular/subcutaneous medicines were usually not preferred because they are felt as inconvenient (intravenous = 33.4% and subcutaneous/intramuscular = 10%) or painful (intravenous = 37.50% and subcutaneous/intramuscular = 10%)Conclusion: Most systemic sclerosis patients are able to take their medication despite having some difficulties. However, as there were clear preferences, we could improve patients’ adherence to drug therapy if taking these preferences into account.
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- 2021
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29. Biomechanical podiatric evaluation in an Italian cohort of patients with systemic sclerosis: A pilot study.
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Bongi, Susanna Maddali, Ravenni, Giovanni, Ciampi, Benedetta, Del Rosso, Angela, and El Aoufy, Khadija
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SYSTEMIC scleroderma ,BIOMECHANICS ,PUBLIC health - Abstract
Objective: Foot problems are often present in Systemic Sclerosis (SSc) patients, however studies regarding podiatric problems related to SSc are lacking and there are no data evaluating the foot biomechanical changes. The aim of the present pilot study was to evaluate podiatric problems in an Italian cohort of SSc patients by assessing received podiatric services, foot pain and disability and biomechanical foot deformity. Material and Methods: 25 consecutive SSc patients were enrolled from the Division of Rheumatology, University of Florence. All SSc patients were assessed by: Standards of Care for People with Foot Musculoskeletal Health problems: Audit Tool, Foot Function Index (FFI), Weight and non-weight bearing foot joint assessment, (Foot Posture Index (FPI) and Gait Cycle), Health Assessment Questionnaire (HAQ) and Medical Outcomes Survey Short Form 36 (SF-36). Results: Audit Tool - Only 7 (28%) out of the 25 patients with SSc had a specific podiatric assessment and treatment: no patient received a foot health assessment within the first 6 months of disease diagnosis and no patient received information about foot involvement. 1 patient (4%) received foot assessment every year; 1 patient (4%) received specific information about the disease and 5 patients (20%) received information about the benefits of using adapted footwear and insoles. FFI - Values of pain, disability and activity limitations, reported in FFI, are 4.7±5.1, 5.1±3.2 and 3.2±3.1 (M±DS), respectively. Non-weight bearing foot joint assessment shows a rearfoot varus deformity in 64% of patients, forefoot varus deformity in 42% and 6% forefoot valgus deformity. Weight bearing foot joint assessment, through FPI shows a pronated foot 20% of patients with and 34% with highly pronated overall foot posture. Gait analysis shows that 64% of patients has a contact of the calcaneus in invertion while 36% in eversion. In the midstance, 78% have the foot in pronation and 22% in supination, while in propulsion 12% presents a takeoff of the foot in supination and 88% in the pronation. HAQ result is 1.13±0.80, SFI and SMI scales of SF-36 have scores of 32.38±10.65 and 38.67±11.40, respectively. Conclusion: Our results shows that podiatric problems in SSc patients are common, serious but foot assessment and health care are inadequate. Thus, foot health information should be improved in order to better empower patients to self-manage low risk problems and help identify high-risk problems, which require specialist care. [ABSTRACT FROM AUTHOR]
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- 2016
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30. A Comparison among Score Systems for Discharging Patients from Recovery Rooms: A Narrative Review.
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El Aoufy K, Forciniti C, Longobucco Y, Lucchini A, Mangli I, Magi CE, Bulleri E, Fusi C, Iovino P, Iozzo P, Rizzato N, Rasero L, and Bambi S
- Abstract
Introduction: The recovery room (RR) is a hospital area where patients are monitored in the early postoperative period before being transferred to the surgical ward or other specialized units. The utilization of scores in the RR context facilitates the assignment of patients to the appropriate ward and directs necessary monitoring. Some scoring systems allow nurses to select patients who can be discharged directly to their homes., Aim and Methods: The aim of this narrative review was to describe and compare the scoring systems employed to discharge postoperative patients from RR, with a focus on item characteristics., Results: Nine scoring systems were identified and discussed: the "Aldrete Score System" and its modified version, the "Respiration, Energy, Alertness, Circulation, Temperature Score", the "Post Anesthetic Discharge Scoring System", the "White and Song Score", the "Readiness for Discharge Assessment Tool", the "Anesthesia and Perioperative Medicine Service Checklist", the "Post-Anesthetic Care Tool", the "Post-operative Quality Recovery Scale", and the "Discerning Post Anesthesia Readiness for Transition" instrument., Discussion and Conclusions: To obtain a comprehensive overview, the items included in the scoring systems were compared. Despite the availability of guidelines for patients' discharge readiness from the RR, there is no universally recommended scoring system. Next-generation scores must be improved to ease their use, minimize errors, and increase safety. The main goals of the scores included in this narrative review were to be simple to use, feasible, intuitive, comprehensive, and flexible. However, these goals frequently conflict because patient assessment takes time, and a smart and comprehensive score may not consider some clinical parameters that may be crucial for the discharge decision. Therefore, further research should be conducted on this topic.
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- 2024
- Full Text
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