14 results on '"Earl E. Johnson"'
Search Results
2. Hearing aid fitting and developmental outcomes of children fit according to either the NAL or DSL prescription: fit-to-target, audibility, speech and language abilities
- Author
-
Teresa Y. C. Ching, Vicky W. Zhang, Karen McGhie, Earl E. Johnson, Laura Button, Lauren Burns, Patricia Van Buynder, Christopher Flynn, and Sanna Hou
- Subjects
Male ,Hearing aid ,Time Factors ,medicine.medical_treatment ,Child Behavior ,Neuropsychological Tests ,Audiology ,01 natural sciences ,Language and Linguistics ,law.invention ,Hearing Aids ,0302 clinical medicine ,Hearing ,Speech Production Measurement ,Randomized controlled trial ,law ,Child ,030223 otorhinolaryngology ,010301 acoustics ,education.field_of_study ,Speech Reception Threshold Test ,Age Factors ,Equipment Design ,Disabled Children ,Treatment Outcome ,Child, Preschool ,Speech Perception ,Female ,medicine.symptom ,Psychology ,High input ,Child Language ,Linguistics and Language ,medicine.medical_specialty ,Adolescent ,Hearing loss ,Population ,Article ,Hearing Loss, Bilateral ,03 medical and health sciences ,Speech and Hearing ,0103 physical sciences ,medicine ,Humans ,Correction of Hearing Impairment ,Medical prescription ,education ,Speech Intelligibility ,Significant difference ,Australia ,Auditory Threshold ,Persons With Hearing Impairments ,Digital subscriber line ,Acoustic Stimulation ,Adolescent Behavior - Abstract
OBJECTIVE: This study examined the influence of prescription on hearing aid (HA) fitting characteristics and 5-year developmental outcomes of children. DESIGN: A randomised controlled trial implemented as part of a population-based study on Longitudinal Outcomes of Children with Hearing Impairment (LOCHI). STUDY SAMPLE: Two-hundred and thirty-two children that were fit according to either the NAL or DSL prescription. RESULTS: Deviation from targets and root-mean-square (rms) error in HA fitting revealed no significant difference between fitting prescriptions. Aided audibility quantified by using the Speech Intelligibility Index (SII) model showed that DSL provided higher audibility than NAL at low and medium input levels but not at high input level. After allowing for hearing loss desensitization, differences in audibility between prescription groups were significant only at low input level. The randomised trial of prescription that was implemented for 163 children revealed no significant between-group differences in speech production, perception, and language; but parent-rated functional performance was higher for the DSL than for the NAL group. CONCLUSIONS: Proximity to prescriptive targets were similar between fitting prescriptions. The randomised trial revealed differences in aided audibility at low input level between prescription groups, but no significant differences in speech and language abilities.
- Published
- 2017
- Full Text
- View/download PDF
3. Hearing-aid safety: A comparison of estimated threshold shifts for gains recommended by NAL-NL2 and DSL m[i/o] prescriptions for children
- Author
-
Earl E. Johnson, Teresa Y. C. Ching, Mark Seeto, and John H. Macrae
- Subjects
Hearing aid ,Linguistics and Language ,medicine.medical_specialty ,Hearing loss ,medicine.medical_treatment ,Audiology ,Article ,Language and Linguistics ,Speech and Hearing ,Threshold shift ,Hearing Aids ,medicine ,Humans ,Medical prescription ,Randomized Controlled Trials as Topic ,business.industry ,Infant ,Auditory Threshold ,Audiogram ,Models, Theoretical ,Digital subscriber line ,Hearing Loss, Noise-Induced ,Hearing level ,Child, Preschool ,medicine.symptom ,business ,Auditory fatigue - Abstract
To investigate the predicted threshold shift associated with the use of nonlinear hearing aids fitted to the NAL-NL2 or the DSL m[i/o] prescription for children with the same audiograms. For medium and high input levels, we asked: (1) How does predicted asymptotic threshold shifts (ATS) differ according to the choice of prescription? (2) How does predicted ATS vary with hearing level for gains prescribed by the two prescriptions?A mathematical model consisting of the modified power law combined with equations for predicting temporary threshold shift (Macrae, 1994b) was used to predict ATS.Predicted threshold shift were determined for 57 audiograms at medium and high input levels.For the 57 audiograms, DSL m[i/o] gains for high input levels were associated with increased risk relative to NAL-NL2. The variation of ATS with hearing level suggests that NAL-NL2 gains became unsafe when hearing loss90 dB HL. The gains prescribed by DSL m[i/o] became unsafe when hearing loss80 dB HL at a medium input level, and70 dB HL at a high input level.There is a risk of damage to hearing for children using nonlinear amplification. Vigilant checking for threshold shift is recommended.
- Published
- 2013
- Full Text
- View/download PDF
4. Modern Prescription Theory and Application: Realistic Expectations for Speech Recognition With Hearing Aids
- Author
-
Earl E. Johnson
- Subjects
Adult ,Hearing aid ,medicine.medical_specialty ,Speech perception ,Hearing Loss, Sensorineural ,Loudness Perception ,Speech recognition ,medicine.medical_treatment ,Context (language use) ,Audiology ,Loudness ,Speech and Hearing ,Hearing Aids ,Prosthesis Fitting ,otorhinolaryngologic diseases ,medicine ,Humans ,Expected return ,Medical prescription ,Sound pressure ,Aged ,Efficient frontier ,Auditory Threshold ,Equipment Design ,Articles ,Middle Aged ,Models, Theoretical ,Child, Preschool ,Speech Discrimination Tests ,Speech Perception ,Psychology - Abstract
A major decision at the time of hearing aid fitting and dispensing is the amount of amplification to provide listeners (both adult and pediatric populations) for the appropriate compensation of sensorineural hearing impairment across a range of frequencies (e.g., 160–10000 Hz) and input levels (e.g., 50–75 dB sound pressure level). This article describes modern prescription theory for hearing aids within the context of a risk versus return trade-off and efficient frontier analyses. The expected return of amplification recommendations (i.e., generic prescriptions such as National Acoustic Laboratories—Non-Linear 2, NAL-NL2, and Desired Sensation Level Multiple Input/Output, DSL m[i/o]) for the Speech Intelligibility Index (SII) and high-frequency audibility were traded against a potential risk (i.e., loudness). The modeled performance of each prescription was compared one with another and with the efficient frontier of normal hearing sensitivity (i.e., a reference point for the most return with the least risk). For the pediatric population, NAL-NL2 was more efficient for SII, while DSL m[i/o] was more efficient for high-frequency audibility. For the adult population, NAL-NL2 was more efficient for SII, while the two prescriptions were similar with regard to high-frequency audibility. In terms of absolute return (i.e., not considering the risk of loudness), however, DSL m[i/o] prescribed more outright high-frequency audibility than NAL-NL2 for either aged population, particularly, as hearing loss increased. Given the principles and demonstrated accuracy of desensitization (reduced utility of audibility with increasing hearing loss) observed at the group level, additional high-frequency audibility beyond that of NAL-NL2 is not expected to make further contributions to speech intelligibility (recognition) for the average listener.
- Published
- 2013
- Full Text
- View/download PDF
5. Practitioners give high marks for user benefit to open-canal mini-BTEs
- Author
-
Earl E. Johnson
- Subjects
Speech and Hearing - Published
- 2008
- Full Text
- View/download PDF
6. Survey finds higher sales and prices, plus more open fittings and directional mics
- Author
-
Earl E. Johnson
- Subjects
Speech and Hearing ,Computer science - Published
- 2007
- Full Text
- View/download PDF
7. OTC Hearing Aids
- Author
-
Earl E. Johnson
- Subjects
Speech and Hearing ,Acquired immunodeficiency syndrome (AIDS) ,business.industry ,Medicine ,Medical emergency ,business ,medicine.disease - Published
- 2018
- Full Text
- View/download PDF
8. Segmenting dispensers
- Author
-
Earl E. Johnson
- Subjects
Speech and Hearing ,business.industry ,Medicine ,Computer vision ,Artificial intelligence ,business - Published
- 2006
- Full Text
- View/download PDF
9. A comparison of NAL and DSL prescriptive methods for paediatric hearing-aid fitting: predicted speech intelligibility and loudness
- Author
-
Lauren Burns, Sanna Hou, Patricia Van Buynder, Angela Wong, Earl E. Johnson, Harvey Dillon, Vicky W. Zhang, Christopher Flynn, and Teresa Y. C. Ching
- Subjects
Hearing aid ,Linguistics and Language ,Loudness Perception ,medicine.medical_specialty ,Speech perception ,Speech recognition ,medicine.medical_treatment ,Audiology ,Language and Linguistics ,Article ,Loudness ,Speech and Hearing ,Hearing Aids ,medicine ,Humans ,Hearing Loss ,Mathematics ,Extramural ,Low input ,Speech Intelligibility ,Infant ,Models, Theoretical ,Digital subscriber line ,Prescriptions ,Child, Preschool ,Speech Perception ,High input - Abstract
To examine the impact of prescription on predicted speech intelligibility and loudness for children.A between-group comparison of speech intelligibility index (SII) and loudness, based on hearing aids fitted according to NAL-NL1, DSL v4.1, or DSL m[i/o] prescriptions. A within-group comparison of gains prescribed by DSL m[i/o] and NAL-NL2 for children in terms of SII and loudness.Participants were 200 children, who were randomly assigned to first hearing-aid fitting with either NAL-NL1, DSL v4.1, or DSL m[i/o]. Audiometric data and hearing-aid data at 3 years of age were used.On average, SII calculated on the basis of hearing-aid gains were higher for DSL than for NAL-NL1 at low input level, equivalent at medium input level, and higher for NAL-NL1 than DSL at high input level. Greater loudness was associated with DSL than with NAL-NL1, across a range of input levels. Comparing NAL-NL2 and DSL m[i/o] target gains revealed higher SII for the latter at low input level. SII was higher for NAL-NL2 than for DSL m[i/o] at medium- and high-input levels despite greater loudness for gains prescribed by DSL m[i/o] than by NAL-NL2.The choice of prescription has minimal effects on speech intelligibility predictions but marked effects on loudness predictions.
- Published
- 2013
10. Effects of degree and configuration of hearing loss on the contribution of high- and low-frequency speech information to bilateral speech understanding
- Author
-
Benjamin W. Y. Hornsby, Earl E. Johnson, and Erin M. Picou
- Subjects
Adult ,Male ,medicine.medical_specialty ,Hearing loss ,Speech recognition ,Hearing Loss, Sensorineural ,Intelligibility (communication) ,Audiology ,Severity of Illness Index ,Article ,Background noise ,Speech and Hearing ,Young Adult ,Linear regression ,otorhinolaryngologic diseases ,medicine ,Humans ,Wideband ,Pitch Perception ,Mathematics ,Aged ,Aged, 80 and over ,Bandwidth (signal processing) ,Linear model ,Auditory Threshold ,Middle Aged ,medicine.disease ,Otorhinolaryngology ,Linear Models ,Speech Discrimination Tests ,Speech Perception ,Sensorineural hearing loss ,Female ,medicine.symptom ,Noise ,Follow-Up Studies - Abstract
Objectives The purpose of this study was to examine the effects of degree and configuration of hearing loss on the use of, and benefit from, information in amplified high- and low-frequency speech presented in background noise. Design Sixty-two adults with a wide range of high- and low-frequency sensorineural hearing loss (5 to 115+ dB HL) participated in the study. To examine the contribution of speech information in different frequency regions, speech understanding in noise was assessed in multiple low- and high-pass filter conditions, as well as a band-pass (713 to 3534 Hz) and wideband (143 to 8976 Hz) condition. To increase audibility over a wide frequency range, speech and noise were amplified based on each individual's hearing loss. A stepwise multiple linear regression approach was used to examine the contribution of several factors to (1) absolute performance in each filter condition and (2) the change in performance with the addition of amplified high- and low-frequency speech components. Results Results from the regression analysis showed that degree of hearing loss was the strongest predictor of absolute performance for low- and high-pass filtered speech materials. In addition, configuration of hearing loss affected both absolute performance for severely low-pass filtered speech and benefit from extending high-frequency (3534 to 8976 Hz) bandwidth. Specifically, individuals with steeply sloping high-frequency losses made better use of low-pass filtered speech information than individuals with similar low-frequency thresholds but less high-frequency loss. In contrast, given similar high-frequency thresholds, individuals with flat hearing losses received more benefit from extending high-frequency bandwidth than individuals with more sloping losses. Conclusions Consistent with previous work, benefit from speech information in a given frequency region generally decreases as degree of hearing loss in that frequency region increases. However, given a similar degree of loss, the configuration of hearing loss also affects the ability to use speech information in different frequency regions. Except for individuals with steeply sloping high-frequency losses, providing high-frequency amplification (3534 to 8976 Hz) had either a beneficial effect on, or did not significantly degrade, speech understanding. These findings highlight the importance of extended high-frequency amplification for listeners with a wide range of high-frequency hearing losses, when seeking to maximize intelligibility.
- Published
- 2011
11. Dispensing rates of four common hearing aid product features: associations with variations in practice among audiologists
- Author
-
Todd A. Ricketts and Earl E. Johnson
- Subjects
Hearing aid ,Adult ,Male ,medicine.medical_specialty ,Health Knowledge, Attitudes, Practice ,Time Factors ,Adolescent ,Attitude of Health Personnel ,medicine.medical_treatment ,Audiologist ,Audiology ,Choice Behavior ,Article ,Speech and Hearing ,Young Adult ,Hearing Aids ,Surveys and Questionnaires ,medicine ,Feature (machine learning) ,Humans ,Product (category theory) ,Child ,Workplace ,Aged ,Aged, 80 and over ,Evidence-Based Medicine ,Guideline adherence ,business.industry ,Infant ,Regression analysis ,Professional Practice ,Evidence-based medicine ,Equipment Design ,Middle Aged ,United States ,Patient population ,Child, Preschool ,Health Care Surveys ,Practice Guidelines as Topic ,Educational Status ,Regression Analysis ,Female ,Guideline Adherence ,business ,Factor Analysis, Statistical - Abstract
The purpose of the study was to develop and examine a list of potential variables that may account for variability in the dispensing rates of four common hearing aid features. A total of 29 potential variables were identified and placed into the following categories: (1) characteristics of the audiologist, (2) characteristics of the hearing aids dispensed by the audiologist, (3) characteristics of the audiologist’s patient population, and (4) evidence-based practice grades of recommendation for each feature. The potentially associative variables then were examined using regression analyses from the responses of 257 audiologists to a dispensing practice survey. There was a direct relation between price and level of hearing aid technology with the frequency of dispensing product features. There was also a direct relation between the belief by the audiologist that a feature might benefit patients and the frequency of dispensing that feature. In general, the results suggested that personal differences among audiologists and the hearing aids audiologists choose to dispense are related more strongly to dispensing rates of product features than to differences in characteristics of the patient population served by audiologists. An additional finding indicated that evidence-based practice recommendations were inversely related to dispensing rates of product features. This finding, however, may not be the result of dispensing trends as much as hearing aid manufacturing trends.
- Published
- 2010
12. Survey explores how dispensers use and choose their preferred hearing aid brands
- Author
-
Earl E. Johnson
- Subjects
Hearing aid ,Speech and Hearing ,medicine.medical_specialty ,medicine.medical_treatment ,medicine ,Audiology ,Psychology - Published
- 2007
- Full Text
- View/download PDF
13. Despite having more advanced features, hearing aids hold line on retail price
- Author
-
Earl E. Johnson
- Subjects
Speech and Hearing ,Acquired immunodeficiency syndrome (AIDS) ,Computer science ,medicine ,Optometry ,Line (text file) ,medicine.disease - Published
- 2008
- Full Text
- View/download PDF
14. The role of calcium in the activation of estrogen receptor-alpha.
- Author
-
Divekar SD, Storchan GB, Sperle K, Veselik DJ, Johnson E, Dakshanamurthy S, Lajiminmuhip YN, Nakles RE, Huang L, and Martin MB
- Subjects
- Cell Line, Tumor, Female, Gene Expression Regulation physiology, Humans, Immunoprecipitation, Mutagenesis, Site-Directed, Protein Structure, Tertiary, Reverse Transcriptase Polymerase Chain Reaction, Signal Transduction physiology, Breast Neoplasms metabolism, Calcium metabolism, Estrogen Receptor alpha metabolism, Receptor Cross-Talk physiology
- Abstract
Environmental estrogen mimics, including metalloestrogens that can activate estrogen receptor-alpha (ERα), may contribute to breast cancer risk. However, the underlying mechanisms through which these molecular mimics activate the ERα are generally poorly understood. With concern to this important question, we investigated whether intracellular calcium may mediate the cross-talk between signaling pathways that activate ERα and the ligand-binding domain of ERα. MCF-7 cells treated with EGF, ATP, extracellular calcium, or caffeine to increase intracellular calcium triggered a rapid recruitment of ERα to estrogen-responsive promoters and stimulated expression of estrogen-responsive genes including pS2, complement C3, and progesterone receptor. Induction was blocked by an antiestrogen but also by the chelation of intracellular calcium. Treatment with extracellular calcium also increased the growth of MCF-7 cells through an ER-dependent mechanism. We found that EGF and extracellular calcium activated the C-terminus of ERα and the activation was blocked by the antiestrogen. Mechanistic investigations identified four potential sites on the solvent-accessible surface of the ERα ligand-binding domain as important for calcium activation of the receptor. Taken together, our results suggest that calcium mediates the cross-talk between ERα-activating signaling pathways and the ligand-binding domain of ERα providing a potential explanation for the ability of certain environmental metalloestrogens to activate the receptor., (©2011 AACR.)
- Published
- 2011
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.