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1. Integer diagonal forms for subset intersection relations

Author

Ducey, Joshua E., Engelthaler, Lauren, Gathje, Jacob, Jones, Brant, Pfaff, Isabel, and Plute, Jenna

Subjects
Mathematics - Combinatorics, 05C50, 05E30
Abstract

For integers $0 \leq \ell \leq k_{r} \leq k_{c} \leq n$, we give a description for the Smith group of the incidence matrix with rows (columns) indexed by the size $k_r$ ($k_c$, respectively) subsets of an $n$-element set, where incidence means intersection in a set of size $\ell$. This generalizes work of Wilson and Bier from the 1990s which dealt only with the case where incidence meant inclusion. Our approach also describes the Smith group of any matrix in the $\mathbb{Z}$-linear span of these matrices so includes all integer matrices in the Bose-Mesner algebra of the Johnson association scheme: for example, the association matrices themselves as well as the Laplacian, signless Laplacian, Seidel adjacency matrix, etc. of the associated graphs. In particular, we describe the critical (also known as sandpile) groups of these graphs. The complexity of our formula grows with the parameters $k_{r}$ and $k_{c}$, but is independent of $n$ and $\ell$, which often leads to an efficient algorithm for computing these groups. We illustrate our techniques to give diagonal forms of matrices attached to the Kneser and Johnson graphs for subsets of size $3$, whose invariants have never before been described, and recover results from a variety of papers in the literature in a unified way., Comment: 28 pages

Published
2023

3. Unveiling errors in soil microbial community sequencing: a case for reference soils and improved diagnostics for nanopore sequencing

Author

Daniel K. Manter, Catherine L. Reardon, Amanda J. Ashworth, Abasiofiok M. Ibekwe, R. Michael Lehman, Jude E. Maul, Daniel N. Miller, Timothy Creed, Patrick M. Ewing, Stanley Park, Thomas F. Ducey, Heather L. Tyler, Kristen S. Veum, Sharon L. Weyers, and David B. Knaebel

Subjects
Biology (General), QH301-705.5
Abstract

Abstract The sequencing platform and workflow strongly influence microbial community analyses through potential errors at each step. Effective diagnostics and experimental controls are needed to validate data and improve reproducibility. This cross-laboratory study evaluates sources of variability and error at three main steps of a standardized amplicon sequencing workflow (DNA extraction, polymerase chain reaction [PCR], and sequencing) using Oxford Nanopore MinION to analyze agricultural soils and a simple mock community. Variability in sequence results occurs at each step in the workflow with PCR errors and differences in library size greatly influencing diversity estimates. Common bioinformatic diagnostics and the mock community are ineffective at detecting PCR abnormalities. This work outlines several diagnostic checks and techniques to account for sequencing depth and ensure accuracy and reproducibility in soil community analyses. These diagnostics and the inclusion of a reference soil can help ensure data validity and facilitate the comparison of multiple sequencing runs within and between laboratories.

Published
2024
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4. Developing a core outcome set for the health outcomes for children and adults with congenital oesophageal atresia and/or tracheo-oesophageal fistula: OCELOT task group study protocol

Author

Nigel J Hall, Anna-may Long, Nick Lansdale, Sebastian King, Lucy Bray, Tom Kovesi, Alex Adams, Jonathan Ducey, Paul Cullis, Shireen A Nah, Lin Yin Ong, Victoria Gray, Paul D Losty, Usha Krishnan, Corne De Vos, Warwick J Teague, Rebecca Thursfield, Sarah Gorst, Nadine Teunissen, Julia Faulkner, Lucia Gutierrez Gammino, Graham Slater, Laura Baird, Julia Brendel, Adam Donne, Eniola Folaranmi, Laura Hopwood, Dan Benscoter, Mike Rutter, and Aaron M Zorn

Subjects
Pediatrics, RJ1-570
Abstract

Introduction Heterogeneity in reported outcomes of infants with oesophageal atresia (OA) with or without tracheo-oesophageal fistula (TOF) prevents effective data pooling. Core outcome sets (COS) have been developed for many conditions to standardise outcome reporting, facilitate meta-analysis and improve the relevance of research for patients and families. Our aim is to develop an internationally-agreed, comprehensive COS for OA-TOF, relevant from birth through to transition and adulthood.Methods and analysis A long list of outcomes will be generated using (1) a systematic review of existing studies on OA-TOF and (2) qualitative research with children (patients), adults (patients) and families involving focus groups, semistructured interviews and self-reported outcome activity packs. A two-phase Delphi survey will then be completed by four key stakeholder groups: (1) patients (paediatric and adult); (2) families; (3) healthcare professionals; and (4) researchers. Phase I will include stakeholders individually rating the importance and relevance of each long-listed outcome using a 9-point Likert scale, with the option to suggest additional outcomes not already included. During phase II, stakeholders will review summarised results from phase I relative to their own initial score and then will be asked to rescore the outcome based on this information. Responses from phase II will be summarised using descriptive statistics and a predefined definition of consensus for inclusion or exclusion of outcomes. Following the Delphi process, stakeholder experts will be invited to review data at a consensus meeting and agree on a COS for OA-TOF.Ethics and dissemination Ethical approval was sought through the Health Research Authority via the Integrated Research Application System, registration no. 297026. However, approval was deemed not to be required, so study sponsorship and oversight were provided by Alder Hey Children’s NHS Foundation Trust. The study has been prospectively registered with the COMET Initiative. The study will be published in an open access forum.

Published
2024
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5. A representation-theoretic computation of the rank of $1$-intersection incidence matrices: $2$-subsets vs. $n$-subsets

Author

Ducey, Joshua E. and Sherwood, Colby J.

Subjects
Mathematics - Combinatorics, Mathematics - Representation Theory, 05E18 (primary), 20C30 (secondary)
Abstract

Let $W_{k,n}^{i}(m)$ denote a matrix with rows and columns indexed by the $k$-subsets and $n$-subsets, respectively, of an $m$-element set. The row $S$, column $T$ entry of $W_{k,n}^{i}(m)$ is $1$ if $|S \cap T| = i$, and is $0$ otherwise. We compute the rank of the matrix $W_{2,n}^{1}(m)$ over any field by making use of the representation theory of the symmetric group. We also give a simple condition under which $W_{k,n}^{i}(m)$ has large $p$-rank., Comment: 13 pages. Corrected the statement of Theorem 2.1, part (v), and consequently needed to modify the proof of the case "char(F)=2, m odd"

Published
2022

6. Variation in Sedative and Analgesic Use During the COVID-19 Pandemic and Associated Outcomes

Author

Mesland, Jean-Baptiste, Henin, Pierre, Petre, Hélène, Buelens, Isabelle, Gerard, Anne-Catherine, Markotić, Dragana, Bošnjak, Ivana, Garza, Ruben, Chu, Eric, Chan, Victoria, Gavidia, Oscar Y., Pachon, Felipe, El Kassas, Mohamed, Tawheed, Ahmed, Matsuda, Wataru, Itagaki, Yuki, Kodate, Akira, Suzuki, Reina, Takahashi, Yuki, Moriki, Koyo, Amer, Marwa Ridha, Bawazeer, Mohammed Abdullah, Dahhan, Talal I., Kseibi, Eiad, Butt, Abid Shahzad, Khurshid, Syed Moazzum, Rabee, Muath, Abujazar, Mohammed, Alghunaim, Razan, Abualkhair, Maal, AlFirm, Abeer Turki, Almazyad, Mohammed A., Alarifi, Mohammed I., Macarambon, Jara M., Bukhari, Ahmad Abdullah, Albahrani, Hussain A., Asfina, Kazi N., Aldossary, Kaltham M., Bojicic, Jovana, Kovacevic, Bojan, Predrag, Stevanovic, Stojakov, Dejan S., Ignjatovic, Duska K., Bojic, Suzana C., Bobos, Marina M., Nenadic, Irina B., Zaric, Milica S., Djuric, Marko D., Djukic, Vladimir R., Teruel, Santiago Y., Martin, Belen C., Kharbanda, Anmol, Jhajhria, Sunil, Fyffe, Zachary, Capizzi, Stephen, Alicie, Bethany, Green, Martha, Crockarell, Lori, Drennan, Amelia, Dubuque, Kathleen, Fambrough, Tonya, Gasaway, Nikole, Krantz, Briana, Nebi, Peiman, Orga, Jan, Serfass, Margaret, Simion, Alina, Warren, Kimberly, Wheeler, Cassie, Woolman, C.J., Christie, Amy B., Ashley, Dennis W., Adiga, Rajani, Newsome, Andrea Sikora, Forehand, Christy C., Bruning, Rebecca, Jones, Timothy W., Walkey, Allan J., Waikar, Sushrut S., Garcia, Michael A., Colona, Mia, Kibbelaar, Zoe, Leong, Michael, Wallman, Daniel, Soni, Kanupriya, Maccarone, Jennifer, Gilman, Joshua, Devis, Ycar, Chung, Joseph, Paracha, Munizay, Lumelsky, David N., DiLorenzo, Madeline, Abdurrahman, Najla, Johnson, Shelsey, Tirupathi, Raghavendra, Tang, Alymer, Safi, Arshad, Green, Cindy, Newell, Jackie, Ramani, Naga, Ganti, Bhavani Harika, Daugherty, Steven K., Atkinson, Sam, Shrimpton, Kelly, Smalls, Norma, Reilkoff, Ronald A., Heneghan, Julia A., Eichen, Sarah, Goertzen, Lexie, Rajala, Scott, Feussom, Ghislaine, Tang, Ben, Cartin-Ceba, Rodrigo, Sen, Ayan, Talaei, Fahimeh, Kashyap, Rahul, Domecq, Juan Pablo, Gajic, Ognjen, Bansal, Vikas, Tekin, Aysun, Lal, Amos, O'Horo, John C., Deo, Neha N., Sharma, Mayank, Qamar, Shahraz, Singh, Romil, Valencia Morales, Diana J., Sharma, Nikhil, Khan, Syed Anjum, Jain, Nitesh Kumar, Koritala, Thoyaja, Khedr, Anwar M., Mushtaq, Hisham A., Jama, Abbas B., Venkata, Chakradhar, Engemann, Miriam, Mantese, Annamarie, Aulakh, Bhagat S., Tripathi, Sandeep, Bandy, Jennifer A., Kreps, Lisa M., Bollinger, Dawn R., Stienecker, Roger Scott, Melendez, Andre G., Brunner, Tressa A., Budzon, Sue M., Heffernan, Jessica L., Souder, Janelle M., Miller, Tracy L., Maisonneuve, Andrea G., Vilella, Antonia L., Kutner, Sara B., Clark, Kacie, Moore, Danielle, Zaren, Howard A., Smith, Stephanie J., Lewis, Grant C., Seames, Lauren, Farlow, Cheryl, Miller, Judy, Broadstreet, Gloria, Martinez, Anthony, Allison, Micheal, Mittal, Aniket, Ruiz, Rafael, Skaanland, Aleta, Ross, Robert, Bernstein, Michael A., Goff, Ian K., Naftilan, Matthew, Mathew, Amal, Williams, Deborah, Murdock, Sue, Ducey, Maryanne, Nelson, Kerianne, Gupta, Neha, Jones, Tracy L., Ayers, Shonda C., Harrell, Amy B., Brown, Brent R., Malone, Kassidy, Sinko, Lauren A., Settle, Lisa M., Sears, Taylor J., McGonagill, Patrick W., Galet, Colette, Hubbard, Janice, Wang, David, Allan, Lauren, Badheka, Aditya, Chegondi, Madhuradhar, Stapleton, Renee D., Dixon, Anne E., Johnson, Olivia, Ardren, Sara S., Burns, Stephanie, Raymond, Anna, Gonyaw, Erika, Hodgdon, Kevin, Housenger, Chloe, Lin, Benjamin, McQuesten, Karen, Pecott-Grimm, Heidi, Sweet, Julie, Ventrone, Sebastian, Khanna, Ashish K., Harris, Lynnette, Cusson, Bruce, Reeves, Brandon, Fanelli, Jessica, Disher, Nataya, Samant, Anusha, DeGroot, Chritian, Youshock, Evan, Ligon, R. Miller, McCartney, Katherine, Garcia, Julio, Iloabachie, Chidi, Flores, Kelsey, VanEenenaam, David, Sands, Lauren, Robinson, Samuel, Sweatt, Nia, Fowler, Jacob, Fram, Madeline, Howard, Easton, Johnson, Kathleen, Udoh, Imoh, Nosow, Lillian, Howard, Lucy Winesett, Minh Pham, Quan Duc, Irfanullah, Aman, Ong, Tiffany, Enwezor, Chukwunyelu Henry, Dabagian, Hannah, Mendoza, Rafael, Rucci, Justin M., Law, Anica C., Bolesta, Scott, Quinn, Emily K., Boman, Karen, Yus, Santiago, Goodspeed, Valerie M., and Kumar, Vishakha

Published
2024
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9. Analysis of the inflection points of height-diameter models

Author

Tzeng Yih Lam and Mark J. Ducey

Subjects
Concavity, Forest inventory and analysis, Generalized height-diameter models, Growth functions, Height-diameter functions, Mixed-effects modeling, Ecology, QH540-549.5
Abstract

The inflection point is an important feature of sigmoidal height-diameter (H-D) models. It is often cited as one of the properties favoring sigmoidal model forms. However, there are very few studies analyzing the inflection points of H-D models. The goals of this study were to theoretically and empirically examine the behaviors of inflection points of six common H-D models with a regional dataset. The six models were the Wykoff (WYK), Schumacher (SCH), Curtis (CUR), Hossfeld IV (HOS), von Bertalanffy-Richards (VBR), and Gompertz (GPZ) models. The models were first fitted in their base forms with tree species as random effects and were then expanded to include functional traits and spatial distribution. The distributions of the estimated inflection points were similar between the two-parameter models WYK, SCH, and CUR, but were different between the three-parameter models HOS, VBR, and GPZ. GPZ produced some of the largest inflection points. HOS and VBR produced concave H-D curves without inflection points for 12.7% and 39.7% of the tree species. Evergreen species or decreasing shade tolerance resulted in larger inflection points. The trends in the estimated inflection points of HOS and VBR were entirely opposite across the landscape. Furthermore, HOS could produce concave H-D curves for portions of the landscape. Based on the studied behaviors, the choice between two-parameter models may not matter. We recommend comparing several three-parameter model forms for consistency in estimated inflection points before deciding on one. Believing sigmoidal models to have inflection points does not necessarily mean that they will produce fitted curves with one. Our study highlights the need to integrate analysis of inflection points into modeling H-D relationships.

Published
2024
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10. What diameter? What height? Influence of measures of average tree size on area-based allometric volume relationships

Author

Yilin Wang, John A. Kershaw, Mark J. Ducey, Yuan Sun, and James B. McCarter

Subjects
Allometric relationships, Stand structure, Volume estimation, Stand-level attributes, Ecology, QH540-549.5
Abstract

Volume is an important attribute used in many forest management decisions. Data from 83 fixed-area plots located in central New Brunswick, Canada, are used to examine how different measures of stand-level diameter and height influence volume prediction using a stand-level variant of Honer’s (1967) volume equation. When density was included in the models (Volume=f(Diameter,Height,Density)) choice of diameter measure was more important than choice of height measure. When density was not included (Volume=f(Diameter,Height)), the opposite was true. For models with density included, moment-based estimators of stand diameter and height performed better than all other measures. For models without density, largest tree estimators of stand diameter and height performed better than other measures. The overall best equation used quadratic mean diameter, Lorey’s height, and density (root mean square error ​= ​5.26 ​m3⋅ha−1; 1.9 % relative error). The best equation without density used mean diameter of the largest trees needed to calculate a stand density index of 400 and the mean height of the tallest 400 trees per ha (root mean square error ​= ​32.08 ​m3⋅ha−1; 11.8 % relative error). The results of this study have some important implications for height subsampling and LiDAR-derived forest inventory analyses.

Published
2024
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11. Ethics, economics and the regulation and adoption of new medical devices: case studies in pelvic floor surgery

Author

Ross Sue, Weijer Charles, Gafni Amiram, Ducey Ariel, Thompson Carmen, and Lafreniere Rene

Subjects
Medical philosophy. Medical ethics, R723-726
Abstract

Abstract Background Concern has been growing in the academic literature and popular media about the licensing, introduction and adoption of surgical devices before full effectiveness and safety evidence is available to inform clinical practice. Our research will seek empirical survey evidence about the roles, responsibilities, and information and policy needs of the key stakeholders in the introduction into clinical practice of new surgical devices for pelvic floor surgery, in terms of the underlying ethical principals involved in the economic decision-making process, using the example of pelvic floor procedures. Methods/Design Our study involves three linked case studies using, as examples, selected pelvic floor surgery devices representing Health Canada device safety risk classes: low, medium and high risk. Data collection will focus on stakeholder roles and responsibilities, information and policy needs, and perceptions of those of other key stakeholders, in seeking and using evidence about new surgical devices when licensing and adopting them into practice. For each class of device, interviews will be used to seek the opinions of stakeholders. The following stakeholders and ethical and economic principles provide the theoretical framework for the study: Stakeholders - federal regulatory body, device manufacturers, clinicians, patients, health care institutions, provincial health departments, and professional societies. Clinical settings in two centres (in different provinces) will be included. Ethics - beneficence, non-maleficence, autonomy, justice. Economics - scarcity of resources, choices, opportunity costs. For each class of device, responses will be analysed to compare and contrast between stakeholders. Applied ethics and economic theory, analysis and critical interpretation will be used to further illuminate the case study material. Discussion The significance of our research in this new area of ethics will lie in providing recommendations for regulatory bodies, device manufacturers, clinicians, health care institutions, policy makers and professional societies, to ensure surgical patients receive sufficient information before providing consent for pelvic floor surgery. In addition, we shall provide a wealth of information for future study in other areas of surgery and clinical management, and provide suggestions for changes to health policy.

Published
2010
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12. Critical group structure from the parameters of a strongly regular graph

Author

Ducey, Joshua E., Duncan, David L., Engelbrecht, Wesley J., Madan, Jawahar V., Piato, Eric, Shatford, Christina S., and Vichitbandha, Angela

Subjects
Mathematics - Combinatorics, 05C50
Abstract

We give simple arithmetic conditions that force the Sylow $p$-subgroup of the critical group of a strongly regular graph to take a specific form. These conditions depend only on the parameters $(v, k, \lambda, \mu)$ of the strongly regular graph under consideration. We give many examples, including how the theory can be used to compute the critical group of Conway's $99$-graph and to give an elementary argument that no $srg(28,9,0,4)$ exists., Comment: 20 pages

Published
2019

16. Evaluation of aggregate stability methods for soil health

Author

Rieke, Elizabeth L., Bagnall, Dianna K., Morgan, Cristine L.S., Flynn, Kade D., Howe, Julie A., Greub, Kelsey L.H., Mac Bean, G., Cappellazzi, Shannon B., Cope, Michael, Liptzin, Daniel, Norris, Charlotte E., Tracy, Paul W., Aberle, Ezra, Ashworth, Amanda, Bañuelos Tavarez, Oscar, Bary, Andy I., Baumhardt, R.L., Borbón Gracia, Alberto, Brainard, Daniel C., Brennan, Jameson R., Briones Reyes, Dolores, Bruhjell, Darren, Carlyle, Cameron N., Crawford, James J.W., Creech, Cody F., Culman, Steve W., Deen, Bill, Dell, Curtis J., Derner, Justin D., Ducey, Thomas F., Duiker, Sjoerd W., Dyck, Miles F., Ellert, Benjamin H., Entz, Martin H., Espinosa Solorio, Avelino, Fonte, Steven J., Fonteyne, Simon, Fortuna, Ann-Marie, Foster, Jamie L., Fultz, Lisa M., Gamble, Audrey V., Geddes, Charles M., Griffin-LaHue, Deirdre, Grove, John H., Hamilton, Stephen K., Hao, Xiying, Hayden, Zachary D., Honsdorf, Nora, Ippolito, James A., Johnson, Gregg A., Kautz, Mark A., Kitchen, Newell R., Kumar, Sandeep, Kurtz, Kirsten S.M., Larney, Francis J., Lewis, Katie L., Liebman, Matt, Lopez Ramirez, Antonio, Machado, Stephen, Maharjan, Bijesh, Martinez Gamiño, Miguel Angel, May, William E., McClaran, Mitchel P., McDaniel, Marshall D., Millar, Neville, Mitchell, Jeffrey P., Moore, Amber D., Moore, Philip A., Jr., Mora Gutiérrez, Manuel, Nelson, Kelly A., Omondi, Emmanuel C., Osborne, Shannon L., Osorio Alcalá, Leodegario, Owens, Phillip, Pena-Yewtukhiw, Eugenia M., Poffenbarger, Hanna J., Ponce Lira, Brenda, Reeve, Jennifer R., Reinbott, Timothy M., Reiter, Mark S., Ritchey, Edwin L., Roozeboom, Kraig L., Rui, Yichao, Sadeghpour, Amir, Sainju, Upendra M., Sanford, Gregg R., Schillinger, William F., Schindelbeck, Robert R., Schipanski, Meagan E., Schlegel, Alan J., Scow, Kate M., Sherrod, Lucretia A., Shober, Amy L, Sidhu, Sudeep S., Solís Moya, Ernesto, St. Luce, Mervin, Strock, Jeffrey S., Suyker, Andrew E., Sykes, Virginia R., Tao, Haiying, Trujillo Campos, Alberto, Van Eerd, Laura L., van Es, Harold M., Verhulst, Nele, Vyn, Tony J., Wang, Yutao, Watts, Dexter B., Wright, David L., Zhang, Tiequan, and Honeycutt, C. Wayne

Published
2022
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17. Factors affecting women’s decision between uterine-preserving versus hysterectomy-based surgery for pelvic organ prolapse

Author

Kaylee Ramage, Ariel Ducey, Natalie V Scime, Erin Knox, and Erin A Brennand

Subjects
Medicine
Abstract

Background: Given the prevalence of women seeking surgical treatment for pelvic organ prolapse (POP), there is a need to understand women’s decision-making regarding uterine-preserving versus hysterectomy-based surgeries. Historically, hysterectomy-based surgeries have been the preferred treatment for pelvic organ prolapse; however, contemporary evidence supports uterine-preserving surgeries as equivalent. At present, the lack of information available to the general public and limited options presented at surgical consultation for pelvic organ prolapse may hinder women’s autonomy as they navigate surgical treatment. Objectives: To examine the factors affecting women’s decision-making processes regarding uterine-preserving or hysterectomy-based surgery for pelvic organ prolapse. Design: This is a qualitative study. Methods: We conducted semi-structured, qualitative interviews with women seeking surgery for pelvic organ prolapse to explore the factors affecting women’s decision-making between hysterectomy-based and uterine-preserving surgeries. Results: Women (n = 26) used clinical and personal factors to determine which surgery was best. Women noted that the lack of evidence (clinical and/or anecdotal) available to them hindered their decision-making, causing them to rely more on their own interpretations of the evidence, what they perceived to be “normal,” and what their surgeon recommended. Even with standardized discussion regarding the existing clinical equipoise between surgeries at the clinical consultation, some women still had misperceptions that hysterectomy-based surgery would convey the lowest risk of prolapse recurrence and be best for severe prolapse. Conclusion: There is a need for more transparency in discussions about prolapse and the factors affecting women’s decision-making for surgical repair of pelvic organ prolapse. Clinicians should be prepared to offer the option of hysterectomy-based or uterine-preserving surgeries and to clearly explain the clinical equipoise between these procedures.

Published
2023
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18. Salvage decision-making based on carbon following an eastern spruce budworm outbreak

Author

Lisa N. Scott, Sean M. Smith, John S. Gunn, Marek Petrik, Mark J. Ducey, Thomas S. Buchholz, and Ethan P. Belair

Subjects
carbon, lasso, eastern spruce budworm, decision-support, discounting, Forestry, SD1-669.5, Environmental sciences, GE1-350
Abstract

Forest disturbances, such as an eastern spruce budworm (Choristoneura fumiferana) outbreak, impact the strength and persistence of forest carbon sinks. Salvage harvests are a typical management response to widespread tree mortality, but the decision to salvage mortality has large implications for the fate of carbon stocks (including forest carbon and harvested wood products) in the near and long terms. In this study, we created decision-support models for salvage harvesting based on carbon after an eastern spruce budworm outbreak. We used lasso regression to determine which stand characteristics (e.g., basal area) are the best predictors of carbon 40 years after an outbreak in both salvage and no salvage scenarios. We modeled carbon at year 40 for different treatment scenarios and discount rates. Treatment scenarios represent residual stand conditions that may be present when an outbreak occurs. Economic discount rates were applied to 40-year carbon values to account for near and long-term carbon storage aspects. We found that the volume and size of eastern spruce budworm host species are significant predictors of salvage preference based on carbon. We found overall that salvaging less volume is recommended to avoid major swings in carbon budgets and that discounting carbon values to apply weight to near or long-term sequestration greatly affects whether salvaging is preferred. Lasso models are constructed for the northeastern US, however, similar concepts may be applied beyond our study area and potentially for other insect outbreaks similar to spruce budworm, such as mountain pine beetle (Dendroctonus ponderosae) or hemlock woolly adelgid (Adelges tsugae). From a policy standpoint widespread salvaging could create a large carbon emissions deficit with the risk of not being fully replenished within a desired timeframe. Since salvaging is often financially driven, especially for private landowners, carbon market payments or incentives for not salvaging is a consideration for future policy.

Published
2023
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19. The critical group of the Kneser graph on $2$-subsets of an $n$-element set

Author

Ducey, Joshua E., Hill, Ian, and Sin, Peter

Subjects
Mathematics - Combinatorics, 05C50
Abstract

In this paper we compute the critical group of the Kneser graph $KG(n,2)$. This is equivalent to computing the Smith normal form of a Laplacian matrix of this graph., Comment: The statement of Lemma 2.2, part (4) was missing a case. This has been corrected, and it has no effect on the rest of the paper

Published
2017

20. The Smith group and the critical group of the Grassmann graph of lines in finite projective space and of its complement

Author

Ducey, Joshua E. and Sin, Peter

Subjects
Mathematics - Combinatorics, Mathematics - Group Theory, 05C50
Abstract

We compute the elementary divisors of the adjacency and Laplacian matrices of the Grassmann graph on $2$-dimensional subspaces in a finite vector space. We also compute the corresponding invariants of the complementary graphs., Comment: 28 pages

Published
2017

21. lakeCoSTR: A tool to facilitate use of Landsat Collection 2 to estimate lake surface water temperatures

Author

C. Herrick, B. G. Steele, J. A. Brentrup, K. L. Cottingham, M. J. Ducey, D. A. Lutz, M. W. Palace, M. C. Thompson, J. V. Trout‐Haney, and K. C. Weathers

Subjects
Google Colaboratory, Google Earth Engine, lakes, Landsat, limnology, remote sensing, Ecology, QH540-549.5
Abstract

Abstract Although remote sensing of lake surface water temperature has been ongoing for decades and has led to important discoveries regarding the warming of lake surface temperature in some regions, the ability to access and use remote sensing data is still primarily limited to remote sensing experts. Effective use of remote sensing data involves technical skills in coding (often in multiple programming languages), application of appropriate atmospheric corrections, and integrating spatially heterogeneous remote sensing data with in situ data obtained at specific geographic locations. To improve access to remote sensing data and broaden the understanding of changes in lake surface water temperature over the past four decades, we created lakeCoSTR (lake Collection 2 Surface Temperature Retrieval), a user‐friendly, cloud‐based script that gives ecologists lacking specialized training in remote sensing the ability to access the Landsat Collection 2 temperature estimates for lakes with a surface area of at least 0.4 ha. Additionally, if in situ data are provided, a paired dataset can be created within the tool. To demonstrate lakeCoSTR, we retrieved surface water temperature data for a lake with a long monitoring history, Lake Sunapee, NH, USA, and compared long‐term surface temperature trends between data obtained via lakeCoSTR and in situ measurements. When compared with Landsat Collection 1 temperature estimates derived from a single‐channel algorithm, the Landsat Collection 2 data from lakeCoSTR required no calibration to in situ data. This suggests that lakeCoSTR can be used to document temporal trends in lakes and to reprocess analyses that relied on Collection 1 data. From 1983 until 2020, remotely sensed surface water temperature estimates at Lake Sunapee increased by 0.07–0.09°C year−1 during July and August, a trend that agreed with long‐term in situ record. As climate change continues to impact freshwater systems, a better understanding of long‐term temperature data will be vital. Remotely sensed data, like those acquired using lakeCoSTR, may provide a window into temperature trends for lakes.

Published
2023
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22. Alternative expressions for stand diameter in complex forests

Author

Mark J. Ducey and John A. Kershaw, Jr.

Subjects
Forest structure, Diameter at breast height, Weibull distribution, Ecology, QH540-549.5
Abstract

Quadratic mean diameter is the most frequently reported descriptor of the diameter distribution of forests. As such, it is often used as an indicator of forest stand structure, developmental stage, and ecological and economic potential. However, quadratic mean diameter can be heavily influenced by the presence or absence of large numbers of small stems in lower canopy strata, and it is also sensitive to left-truncation of the diameter distribution, making its interpretation across inventories with different protocols challenging. Here, we examine three alternative expressions of stand diameter: the arithmetic and quadratic mean diameter of the thickest 100 trees per hectare, and the basal area-weighted mean diameter. Using data from the United States Forest Inventory and Analysis program for New York and New England, these alternative expressions showed closer correlation with multiple stand structural variables than did quadratic mean diameter, including merchantable cubic and board foot volume per hectare, aboveground live tree carbon per hectare, and total number of live and dead standing trees greater than 40 ​cm diameter at breast height per hectare (previously proposed as an index of old-growth structure). Arithmetic and quadratic mean diameter of the thickest 100 trees per hectare showed nearly identical performance, and the strongest correlations across the board. We develop closed-form expressions for these variables when the diameter distribution is a Weibull, and illustrate their behavior relative to quadratic mean diameter for that situation. While the reasons for prevalence of quadratic mean diameter as an indicator remain valid, we suggest that these alternative measures should be more widely reported and analyzed to give a more informative depiction of stand structure and development in complex forests.

Published
2023
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23. Eight decades of compositional change in a managed northern hardwood landscape

Author

Mark J. Ducey, Olivia L. Fraser, Mariko Yamasaki, Ethan P. Belair, and William B. Leak

Subjects
Northern hardwoods, Succession, Stand dynamics, Silviculture, Ecology, QH540-549.5
Abstract

We analyzed over 8 decades of change in forest composition (represented by species proportion of basal area) and size class from more than 400 permanent plots located on the Bartlett Experimental Forest in the White Mountains of New Hampshire. These data represent one of the longest-term landscape-scale records of forest change based on permanent plots in North America. We analyzed the plots based on elevation class, land type indicating assumed successional direction (grouped into coniferous and deciduous), and inventory period within managed and unmanaged portions of the forest. An ongoing shift from small- to large-diameter stems is clear across all species, in response to the overall aging of the forest following exploitative harvesting in the 19th century. Major compositional changes include a continuing decline in shade-intolerant species (paper birch and aspen), along with the mid-tolerant yellow birch. An increase in red maple abundance through the early 1990s has leveled off or reversed. Among shade-tolerant species, increases in beech and red spruce were largely consistent with assumed land type on unmanaged plots, but heavy marking against diseased beech on managed plots restricted increase of that species. Sugar maple declined in abundance except where silvicultural intervention helped maintain it. By contrast, eastern hemlock showed a continuing expansion at all elevations below 600 m. The data continue to show little or no evidence of upward migration of species, despite evidence of recent regional change in climate. However, the BEF is poised for substantial changes when emerald ash borer and hemlock woolly adelgid, both of which are known to infest nearby areas, do arrive.

Published
2023
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24. Evaluation of a Novel Handoff Communication Strategy for Patients Admitted from the Emergency Department

Author

Smith, Christopher J., Buzalko, Russell J., Anderson, Nathan, Michalski, Joel, Warchol, Jordan, Ducey, Stephen, and Branecki, Chad E.

Subjects
patient handoff, patent transfer, care transition, hosptial communication systems
Abstract

Introduction: Miscommunication during inter-unit handoffs between emergency and internal medicine physicians may jeopardize patient safety.  Our goal was to evaluate the impact of a structured communication strategy on the quality of admission handoffs. Methods: We conducted a mixed-methods, pre-test/post-test study at a 560-bed academic health center with 60,000 emergency department (ED) patient visits per year. Admission-handoff best practices were integrated into a modified SBAR format, resulting in the Situation, Background, Assessment, Responsibilities & Risk, Discussion & Disposition, Read-back & Record (SBAR-DR) model. Physician handoff conversations were recorded and transcribed for the 60 days before (n=110) and 60 days after (n=110) introduction of the SBAR-DR strategy. Transcriptions were scored by two blinded physicians using a 16-item scoring instrument. The primary outcome was the composite handoff quality score. We assessed physician perceptions via a post-intervention survey. Results: The composite quality score improved in the post-intervention phase (7.57 + 2.42 vs. 8.45 + 2.51, p=.0085). Three of the 16 individual scoring elements also improved, including time for questions (70.6% vs. 82.7%, p=.0344) and confirmation of disposition plan (41.8% vs. 62.7%, p=.0019). The majority of emergency and internal medicine physicians felt that the SBAR-DR model had a positive impact on patient safety and handoff efficiency.  Conclusion: Implementation of the SBAR-DR strategy resulted in improved verbal handoff quality. Agreement upon a clear disposition plan was the most improved element, which is of great importance in delineating responsibility of care and streamlining ED throughput. Future efforts should focus on nurturing broader physician buy-in to facilitate institution-wide implementation.

Published
2018

25. Between Transmission and Silence: Recovering Harki Memories in The Art of Losing

Author

Joanna Ducey

Subjects
french-algerian literature, algerian war, harki narrative, postmemory, transgenerational trauma, exile, generation 2.5, Literature (General), PN1-6790, Social sciences (General), H1-99
Abstract

Alice Zeniter’s 2017 novel The Art of Losing, translated recently by Frank Wynne from French to English, explores how buried histories resurface and haunt generations to come, despite national efforts to ignore, if not minimalize, the enduring impacts of colonialism, independence struggles and exile. Set in contemporary France in the wake of the 2015 terrorist attacks, and loosely inspired by Zeniter’s own family history, the book follows Naïma, a young woman of Algerian decent who grapples with a largely unknown and misconstrued harki heritage. Drawing on Marianne Hirsch’s concept of postmemory, this article investigates intergenerational transmission of memory, trauma, and silence around themes such as war, exile and integration.

Published
2021
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26. Developing a core outcome set for the health outcomes for children and adults with congenital oesophageal atresia and/or tracheo-oesophageal fistula:OCELOT task group study protocol

Author

Ducey, Jonathan, Lansdale, Nick, Gorst, Sarah, Bray, Lucy, Teunissen, Nadine, Cullis, Paul, Faulkner, Julia, Gray, Victoria, Gammino, Lucia Gutierrez, Slater, Graham, Baird, Laura, Adams, Alex, Brendel, Julia, Donne, Adam, Folaranmi, Eniola, Hopwood, Laura, Long, Anna May, Losty, Paul D., Benscoter, Dan, de Vos, Corné, King, Sebastian, Kovesi, Tom, Krishnan, Usha, Nah, Shireen A., Ong, Lin Yin, Rutter, Mike, Teague, Warwick J., Zorn, Aaron M., Hall, Nigel J., Thursfield, Rebecca, Ducey, Jonathan, Lansdale, Nick, Gorst, Sarah, Bray, Lucy, Teunissen, Nadine, Cullis, Paul, Faulkner, Julia, Gray, Victoria, Gammino, Lucia Gutierrez, Slater, Graham, Baird, Laura, Adams, Alex, Brendel, Julia, Donne, Adam, Folaranmi, Eniola, Hopwood, Laura, Long, Anna May, Losty, Paul D., Benscoter, Dan, de Vos, Corné, King, Sebastian, Kovesi, Tom, Krishnan, Usha, Nah, Shireen A., Ong, Lin Yin, Rutter, Mike, Teague, Warwick J., Zorn, Aaron M., Hall, Nigel J., and Thursfield, Rebecca

Abstract

Introduction Heterogeneity in reported outcomes of infants with oesophageal atresia (OA) with or without tracheo-oesophageal fistula (TOF) prevents effective data pooling. Core outcome sets (COS) have been developed for many conditions to standardise outcome reporting, facilitate meta-analysis and improve the relevance of research for patients and families. Our aim is to develop an internationally-agreed, comprehensive COS for OA-TOF, relevant from birth through to transition and adulthood. Methods and analysis A long list of outcomes will be generated using (1) a systematic review of existing studies on OA-TOF and (2) qualitative research with children (patients), adults (patients) and families involving focus groups, semistructured interviews and self-reported outcome activity packs. A two-phase Delphi survey will then be completed by four key stakeholder groups: (1) patients (paediatric and adult); (2) families; (3) healthcare professionals; and (4) researchers. Phase I will include stakeholders individually rating the importance and relevance of each long-listed outcome using a 9-point Likert scale, with the option to suggest additional outcomes not already included. During phase II, stakeholders will review summarised results from phase I relative to their own initial score and then will be asked to rescore the outcome based on this information. Responses from phase II will be summarised using descriptive statistics and a predefined definition of consensus for inclusion or exclusion of outcomes. Following the Delphi process, stakeholder experts will be invited to review data at a consensus meeting and agree on a COS for OA-TOF. Ethics and dissemination Ethical approval was sought through the Health Research Authority via the Integrated Research Application System, registration no. 297026. However, approval was deemed not to be required, so study sponsorship and oversight were provided by Alder Hey Children’s NHS Foundation Trust. The study has been prospecti

Published
2024

27. On the critical group of the missing Moore graph

Author

Ducey, Joshua E.

Subjects
Mathematics - Combinatorics, 05C50
Abstract

We consider the critical group of a hypothetical Moore graph of diameter $2$ and valency $57$. Determining this group is equivalent to finding the Smith normal form of the Laplacian matrix of such a graph. We show that all of the Sylow $p$-subgroups of the critical group must be elementary abelian with the exception of $p = 5$. We prove that the $5$-rank of the Laplacian matrix determines the critical group up to two possibilities., Comment: 9 pages, minor corrections

Published
2015

28. The Smith and Critical Groups of the Square Rook's Graph and its Complement

Author

Ducey, Joshua E., Gerhard, Jonathan, and Watson, Noah

Subjects
Mathematics - Combinatorics, 05C50
Abstract

Let $R_{n}$ denote the graph with vertex set consisting of the squares of an $n \times n$ grid, with two squares of the grid adjacent when they lie in the same row or column. This is the square rook's graph, and can also be thought of as the Cartesian product of two complete graphs of order $n$, or the line graph of the complete bipartite graph $K_{n,n}$. In this paper we compute the Smith group and critical group of the graph $R_{n}$ and its complement. This is equivalent to determining the Smith normal form of both the adjacency and Laplacian matrix of each of these graphs. In doing so we verify a 1986 conjecture of Rushanan.

Published
2015

29. An approximate point-based alternative for the estimation of variance under big BAF sampling

Author

Thomas B. Lynch, Jeffrey H. Gove, Timothy G. Gregoire, and Mark J. Ducey

Subjects
Bitterlich sampling, Delta method, Double sampling, Estimator bias, Forest inventory, Horizontal point sampling, Ecology, QH540-549.5
Abstract

Abstract Background A new variance estimator is derived and tested for big BAF (Basal Area Factor) sampling which is a forest inventory system that utilizes Bitterlich sampling (point sampling) with two BAF sizes, a small BAF for tree counts and a larger BAF on which tree measurements are made usually including DBHs and heights needed for volume estimation. Methods The new estimator is derived using the Delta method from an existing formulation of the big BAF estimator as consisting of three sample means. The new formula is compared to existing big BAF estimators including a popular estimator based on Bruce’s formula. Results Several computer simulation studies were conducted comparing the new variance estimator to all known variance estimators for big BAF currently in the forest inventory literature. In simulations the new estimator performed well and comparably to existing variance formulas. Conclusions A possible advantage of the new estimator is that it does not require the assumption of negligible correlation between basal area counts on the small BAF factor and volume-basal area ratios based on the large BAF factor selection trees, an assumption required by all previous big BAF variance estimation formulas. Although this correlation was negligible on the simulation stands used in this study, it is conceivable that the correlation could be significant in some forest types, such as those in which the DBH-height relationship can be affected substantially by density perhaps through competition. We derived a formula that can be used to estimate the covariance between estimates of mean basal area and the ratio of estimates of mean volume and mean basal area. We also mathematically derived expressions for bias in the big BAF estimator that can be used to show the bias approaches zero in large samples on the order of 1 n $\frac {1}{n}$ where n is the number of sample points.

Published
2021
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30. Neurologic Manifestations of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Hospitalized Patients During the First Year of the COVID-19 Pandemic

Author

Anna M. Cervantes-Arslanian, MD, Chakradhar Venkata, MD, Pria Anand, MD, Joseph D. Burns, MD, Charlene J. Ong, MD, Allison M. LeMahieu, MS, Phillip J. Schulte, PhD, Tarun D. Singh, MD, Alejandro A. Rabinstein, MD, Neha Deo, BS, Vikas Bansal, MBBS, MPH, Karen Boman, BS, Juan Pablo Domecq Garces, MD, Donna Lee Armaignac, PhD, APRN, Amy B. Christie, MD, Roman R. Melamed, MD, Yasir Tarabichi, MD, MSCR, Sreekanth R. Cheruku, MD, MPH, Ashish K. Khanna, MD, FCCP, FCCM, FASA, Joshua L. Denson, MD, MS, Valerie M. Banner-Goodspeed, MPH, Harry L. Anderson, III, MD, FACS, FICS, FCCM, FCCP, FAIM, Ognjen Gajic, MD, MS, Vishakha K. Kumar, MD, MBA, Allan Walkey, MD, Rahul Kashyap, MD, MBA, on behalf of the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS): COVID-19 Registry Investigator Group, Jean-Baptiste Mesland, Pierre Henin, Hélène Petre, Isabelle Buelens, Anne-Catherine Gerard, Philippe Clevenbergh, Rolando Claure-Del Granado, Jose A. Mercado, Esdenka Vega-Terrazas, Maria F. Iturricha-Caceres, Ruben Garza, Eric Chu, Victoria Chan, Oscar Y Gavidia, Felipe Pachon, Yeimy A Sanchez, Danijel knežević, Mohamed El Kassas, Mohamed Badr, Ahmed Tawheed, Hend Yahia, Dimitrios Kantas, Vasileios Koulouras, Estela Pineda, Gabina María Reyes Guillen, Helin Archaga Soto, Ana Karen Vallecillo Lizardo, Csaba Kopitkó, Ágnes Bencze, István Méhész, Zsófia Gerendai,, Girish Vadgaonkar, Rekha Ediga, Shilpa Basety, Shwetha Dammareddy, Phani Sreeharsha Kasumalla, Smitha S. Segu, Tuhin Chakraborty, Epcebha Joyce, Sridhar Papani, Mahesh Kamuram, Mradul Kumar Daga, Munisha Agarwal, Ishan Rohtagi, Anusha Cherian, Sreejith Parameswaran, Magesh Parthiban, Phaneendra Doddaga, Neethi Chandra, Puneet Rijhwani, Ashish Jain, Aviral Gupta, Ram Mohan Jaiswal, Ambika Tyagi, Nimish Mathur, Madhav Prabhu, Vishal Jakati, Mukur Petrolwala, Bharat Ladva, Surapaneni Krishna Mohan, Ekambaram Jyothisree, Umamaheswara Raju, Janaki Manduva, Naresh Kolakani, Shreeja Sripathi, Sheetal Chaitanya, Kamlesh Kumar Agrawal, Vijendra Baghel, Kirti Kumar Patel, Nooshin Dalili, Mohsen Nafa, Wataru Matsuda, Reina Suzuki, Michihito Kyo, Shu Tahara, Mineji Hayakawa, Kunihiko Maekawa, Masamitsu Sanui, Sho Horikita, Yuki Itagaki, Akira Kodate, Yuki Takahashi, Koyo Moriki, Takuya Shiga, Yudai Iwasaki, Hidenobu Shigemitsu, Yuka Mishima, Nobuyuki Nosaka, Michio Nagashima, Abdulrahman Al-Fares, Rene Rodriguez-Gutierrez, Jose Gerardo Gonzalez-Gonzalez, Alejandro Salcido-Montenegro, Adrian Camacho-Ortiz, Mariana Janeth Hermosillo Ulloa, Fatimah Hassan-Hanga, Hadiza Galadanci, Abubakar Shehu Gezawa, Halima M. S. Kabara, Taiwo Gboluwaga Amole, Halima Kabir, Dalha Gwarzo Haliru, Abdullahi S Ibrahim, Muhammad Sohaib Asghar, Mashaal Syed, Syed Anosh Ali Naqvi, Igor Borisovich Zabolotskikh,, Konstantin Dmitrievich Zybin, Sergey Vasilevich Sinkov, Tatiana Sergeevna Musaeva, Razan K Alamoudi, Hassan M. AlSharif, Sarah A. Almazwaghi, Mohammed S Elsakran, Mohamed A Aid, Mouaz A Darwich, Omnia M Hagag, Salah A Ali, Alona rocacorba, Kathrine Supeña, Efren Ray Juane, Jenalyn Medina, Jowany Baduria, Marwa Ridha Amer, Mohammed Abdullah, Bawazeer, Talal I. Dahhan, Eiad Kseibi, Abid Shahzad Butt, Syed Moazzum Khurshid, Muath Rabee, Mohammed Abujazar, Razan Alghunaim, Maal Abualkhair, Abeer Turki AlFirm, Yaseen M Arabi, Sheryl Ann Abdukahil, Mohammed A Almazyad, Mohammed I Alarifi, Jara M Macarambon, Ahmad Abdullah Bukhari, Hussain A. Albahrani, Kazi N Asfina, Kaltham M Aldossary, Marija Zdravkovic, Zoran Todorovic, Viseslav Popadic, Slobodan Klasnja, Ana Andrijevic, Srdjan Gavrilovic, Vladimir Carapic, Bojan Kovacevic, Jovana Bojicic, Stevanovic Predrag, Dejan S Stojakov, Duska K Ignjatovic, Suzana C Bojic, Marina M Bobos, Irina B Nenadic, Milica S Zaric, Marko D Djuric, Vladimir R Djukic, Santiago Y. Teruel, Belen C. Martin, Uluhan Sili, Huseyin Bilgin, Pinar Ay, Varsha P Gharpure, Usman Raheemi, Kenneth W. Dodd, Nicholas Goodmanson, Kathleen Hesse, Paige Bird, Chauncey Weinert, Nathan Schoenrade, Abdulrahman Altaher, Esmael Mayar, Matthew Aronson, Tyler Cooper, Monica Logan, Brianna Miner, Gisele Papo, Eric M. Siegal, Phyllis Runningen, Suzanne Barry, Christopher Woll, Gregory Wu, Erin Carrole, Kathryn Burke, Mustafa Mohammed, Roman R. Melamed, David M. Tierney, Love A. Patel, Vino S. Raj, Barite U. Dawud, Narayana Mazumder, Abbey Sidebottom, Alena M. Guenther, Benjamin D. Krehbiel, Nova J. Schmitz, Stacy L. Jepsen, Lynn Sipsey, Anna Schulte, Whitney Wunderlich, Cecely Hoyt, Abhijit A Raval, Andrea Franks, Katherine Irby, Ronald C. Sanders, Jr., Glenda Hefley, Jennifer M. Jarvis, Anmol Kharbanda, Sunil Jhajhria, Zachary Fyffe, Stephen Capizzi, Bethany Alicie, Martha Green, Lori Crockarell, Amelia Drennan, Kathleen Dubuque, Tonya Fambrough, Nikole Gasaway, Briana Krantz, Peiman Nebi, Jan Orga, Margaret Serfass, Alina Simion, Kimberly Warren, Cassie Wheeler, CJ Woolman, Amy B. Christie, Dennis W. Ashley, Rajani Adiga, Andrew S. Moyer, George M. Verghese, Andrea Sikora Newsome, Christy C. Forehand, Rebecca Bruning, Timothy W. Jones, Moldovan Sabov, Fatema Zaidi, Fiona Tissavirasingham, Dhatri Malipeddi, Jarrod M Mosier, Karen Lutrick, Beth Salvagio Campbell, Cathleen Wilson, Patrick Rivers, Jonathan Brinks, Mokenge Ndiva Mongoh, Boris Gilson, Donna Lee Armaignac, Don Parris, Maria Pilar Zuniga, Ilea Vargas, Viviana Boronat, Anneka Hutton, Navneet Kaur, Prashank Neupane, Nohemi Sadule-Rios, Lourdes M. Rojas, Aashish Neupane, Priscilla Rivera, Carlos Valle Carlos, Gregory Vincent, Mahesh Amin, Mary E Schelle, Amanda Steadham, Christopher M Howard, Cameron McBride, Jocelyn Abraham, Orlando Garner, Katherine Richards, Keegan Collins, Preethi Antony, Sindhu Mathew, Valerie C. Danesh, Gueorgui Dubrocq, Amber L. Davis, Marissa J Hammers, ill M. McGahey, Amanda C. Farris, Elisa Priest, Robyn Korsmo, Lorie Fares, Kathy Skiles, Susan M. Shor, Kenya Burns, Corrie A Dowell, Gabriela “Hope” Gonzales, Melody Flores, Lindsay Newman, Debora A Wilk, Jason Ettlinger, Jaccallene Bomar, Himani Darji, Alejandro Arroliga, Alejandro C Arroliga, Corrie A. Dowell, Gabriela Hope Conzales, Debora A. Wilk, Paras B. Khandhar, Elizabeth Kring, Valerie M. Banner-Goodspeed, Somnath Bose, Lauren E. Kelly, Melisa Joseph, Marie McGourty, Krystal Capers, Benjamin Hoenig, Maria C. Karamourtopoulos, Anica C. Law, Elias N. Baedorf Kassis, Allan J. Walkey, Sushrut S. Waikar, Michael A. Garcia, Mia Colona, Zoe Kibbelaar, Michael Leong, Daniel Wallman, Kanupriya Soni, Jennifer Maccarone, Joshua Gilman, Ycar Devis, Joseph Chung, Munizay Paracha, David N. Lumelsky, Madeline DiLorenzo, Najla Abdurrahman, Shelsey Johnson, Maj Andrew M. Hersh, CPT Stephanie L Wachs, Brittany S. Swigger, Stephanie L Wachs, Capt Lauren A. Sattler, Capt Michael N. Moulton, Kimberly Zammit, Patrick, J McGrath, William Loeffler, Maya, R. Chilbert, Aaron S. Miller, Edwin L. Anderson, Rosemary Nagy, Ravali R. Inja, Pooja A. Nawathe, Isabel Pedraza, Jennifer Tsing, Karen Carr, Anila Chaudhary, Kathleen Guglielmino, Raghavendra Tirupathi, Alymer Tang, Arshad Safi, Cindy Green, Jackie Newell, Rayan E. Ihle, Shelda A. Martin, Elaine A. Davis, Katja M. Gist, Imran A Sayed, John Brinton, Larisa Strom, Kathleen Chiotos, Allison M. Blatz, Giyoung Lee, Ryan H. Burnett, Guy I. Sydney, Danielle M. Traynor, Karissa Nauert, Annika Gonzalez, Mariel Bagley, Anita Santpurkar, Salim Surani, Joshua White, Aftab Khan, Rahul Dhahwal, Sreekanth Cheruku, Farzin Ahmed, Christopher Deonarine, Ashley Jones, Mohammad-Ali Shaikh, David Preston, Jeanette Chin, Vidula Vachharajani, Abhijit Duggal, Prabalini Rajendram, Omar Mehkri, Siddharth Dugar, Michelle Biehl, Gretchen Sacha, Stuart Houltham, Alexander King, Kiran Ashok, Bryan Poynter, Mary Beukemann, Richard Rice, Susan Gole, Valerie Shaner, Adarsh Conjeevaram, Michelle Ferrari, Narendrakumar Alappan, Steven Minear, Jaime Hernandez-Montfort, Syed Sohaib Nasim, Ravi Sunderkrishnan, Debasis Sahoo, Patrick S. Milligan, Sandeep K. Gupta, Joy M. Koglin, Regina Gibson, Lana Johnson, Felicia Preston, Crimson Scott, Bethany Nungester, Dana D Byrne, Christa A Schorr, Katie Grant, Katherine L Doktor, Maura C Porto, Olga Kaplan, James E. Siegler, III, Brian Schonewald, Ashley Woodford, Alan Tsai, Savina Reid, Kuntal Bhowmick, Saba Daneshpooy, Cyrus Mowdawalla, Trishna Akshay Dave, Wilhemina Kennedy, Connor Crudeli, Christopher Ferry, Long Nguyen, Sneha Modi, Niharika Padala, Pavan Jitendra Patel, Belle Lin, Lena Chatterjee, Jamie Qiuyun, Fan Mandi Liu, Rasagna Kota, Annesha Banerjee, Steven K. Daugherty, Sam Atkinson, Kelly Shrimpton, Sidney Ontai, Brian Contreras, Uzoma Obinwanko, Nneka Amamasi, Amir Sharafi, Sarah Lee, Zahia Esber, Chetna Jinjvadia, Raquel R Bartz, Vijay Krishnamoorthy, Bryan Kraft, Aaron Pulsipher, Eugene Friedman, Sachin Mehta, Margit Kaufman, Gregg Lobel, Nisha Gandhi, Amr Abdelaty, Elizabeth Shaji, Kiana Lim, Juan Marte, Dani Ashley Sosa, David P. Yamane, Ivy Benjenk, Nivedita Prasanna, Nicholas Perkins, Prera J. Roth, Banu Sivaraj, Haley Fulton, Madison G Herin, Marissa Crum, Morgan E. Fretwell, Emily-Rose Zhou, Christine Waller, Kara Kallies, Jonean Thorsen, Alec Fitzsimmons, Haley Olsen, Heda R. Dapul, Sourabh Verma, Alan Salas, Ariel Daube, Michelle Korn, Michelle Ramirez, Logi Rajagopalan, Laura Santos, Héctor Collazo Santiago, Ricardo Alan Hernandez, Norma Smalls, Asher G Bercow, Mark Shlomovich, Christine Crandall, Sasko Stojanovski, Kristin Johnson, Kelly Michienzi, Steven Q. Davis, Valentina Jovic, Max Masuda, Amanda Hayes, Katharine Nault, Michael Smith, William Snow, Riley Liptak, Hannah Durant, Valerie Pendleton, Alay Nanavati, Risa Mrozowsk, Namrata Nag, Jeff Brauer, Ashwin Dharmadhikari, Sahib Singh, Franco Laghi, Ghania Naeem, Andrew Wang, Kevin Bliden, Amit Rout, Jaime Barnes, Martin Gesheff, Asha Thomas, Melbin Thomas, Alicia R. Liendo, Jovan Milosavljevic, Kenan Abbasi, Nicholas B. Burley, Nicole Rapista, Samuel Amankwah, Sanjay K Poude, Saroj Timilsina, Sauradeep Sarkar, Oluwasayo Akinyosoye, Shashi K. Yalamanchili, Sheena Moorthy, Sonia Sugumar, Jonathan Ford, Martin C. Taylor, Charlotte Dunderdale, Alyssa Henshaw, Mary K. Brunk, Jessica Hagy, Shehryar Masood, Sushrutha Sridhar, Yuk Ming Liu, Sarah Zavala, Esther Shim, Ronald A. Reilkoff, Julia A. Heneghan, Sarah Eichen, Lexie Goertzen, Scott Rajala, Ghislaine Feussom, Ben Tang, Christine C. Junia, Robert Lichtenberg, Hasrat Sidhu, Diana Espinoza, Shelden Rodrigues, Maria Jose Zabala, Daniela Goyes, Ammu Susheela, Buddhi Hatharaliyadda, Naveen Rameshkumar, Amulya Kasireddy, Genessis Maldonado, Lisseth Beltran, Akshata Chaugule, Hassan Khan, Namrata Patil, Ruhi Patil, Rodrigo Cartin-Ceba, Ayan Sen, Fahimeh Talaei, Rahul Kashyap, Juan Pablo Domecq, Ognjen Gajic, Vikas Bansal, Aysun Tekin, Amos Lal, John C. O’Horo, Neha N. Deo, Mayank Sharma, Shahraz Qamar, Romil Singh, Diana J. Valencia Morales, Abigail T. La Nou, Marija Bogojevic, Simon Zec, Devang Sanghavi, Pramod Guru, Pablo Moreno Franco, Karthik Gnanapandithan, Hollie Saunders, Zachary Fleissner, Juan Garcia, Alejandra Yu Lee Mateus, Siva Naga Yarrarapu, Nirmaljot Kaur, Abhisekh Giri, Mohammed Mustafa Hasan, Ashrita Donepudi, Syed Anjum Khan, Nitesh Kumar Jain, Thoyaja Koritala, Alexander Bastidas, Gabriela Orellana, Adriana Briceno Bierwirth, Eliana Milazzo, Juan Guillermo Sierra, Thao Dang, Rahul S Nanchal, Paul A Bergl, Jennifer L Peterson, Jessica Timmer, Kimberly Welker, Travis Yamanaka, Nicholas A. Barreras, Michael Markos, Anita Fareeduddin, Rohan Mehta, Chakradhar Venkata, Miriam Engemann, Annamarie Mantese, Yasir Tarabichi, Adam Perzynski, Christine Wang, Dhatri Kotekal, Adriana C Briceno Bierwirth, Gabriela M Orellana, Gerardo Catalasan, Shohana Ahmed, Carlos F Matute, Ahmad Hamdan, Ivania Salinas, Genesis Del Nogal, Angel Tejada, Anna Eschler, Mary Hejna, Emily Lewandowski, Kristen Kusmierski, Clare Martin, Jen-Ting Chen, Aluko Hope, Zoe Tsagaris, Elise Ruen, Aram Hambardzumyan, Nasar A Siddiqi, Lesly Jurado, Lindsey Tincher, Carolyn Brown, Prithvi Sendi, Meghana Nadiger, Balagangadhar Totapally, Bhagat S. Aulakh, Sandeep Tripathi, Jennifer A. Bandy, Lisa M. Kreps, Dawn R. Bollinger, Neha Gupta, Brent R Brown, Tracy L Jones, Kassidy Malone, Lauren A Sinko, Amy B Harrell, Shonda C Ayers, Lisa M Settle, Taylor J Sears, Roger Scott Stienecker, Andre G. Melendez, Tressa A. Brunner, Sue M Budzon, Jessica L. Heffernan, Janelle M. Souder, Tracy L. Miller, Andrea G. Maisonneuve, Roberta E. Redfern, Jessica Shoemaker, Jennifer Micham, Lynn Kenney, Gabriel Naimy, Victoria Schauf, Sara Utley, Holly Balcer, Kerry P. J. Pulver, Jennifer Yehle, Alicia Weeks, Terra Inman, Majdi Hamarshi, Jeannette Ploetz, Nick Bennett, Kyle Klindworth, Moustafa Younis, Adham Mohamed, Brian L. Delmonaco, Anthony Franklin, Mitchell Heath, Diane Barkas, Antonia L. Vilella, Sara B. Kutner, Kacie Clark, Danielle Moore, Shina Menon, John K McGuire, Deana Rich, Harry L. Anderson, III, Dixy Rajkumar, Ali Abunayla, Jerrilyn Heiter, Howard A. Zaren, Stephanie J. Smith, Grant C. Lewis, Lauren Seames, Cheryl Farlow, Judy Miller, Gloria Broadstreet, John Lin, Cindy Terrill, Brock Montgomery, Sydney Reyes, Summer Reyes, Alex Plattner, Anthony Martinez, Micheal Allison, Aniket Mittal, Rafael Ruiz, Aleta Skaanland, Robert Ross, Umang Patel, Jordesha Hodge, Krunal Kumar Patel, Shivani Dalal, Himanshu Kavani, Sam Joseph, Michael A. Bernstein, Ian K. Goff, Matthew Naftilan, Amal Mathew, Deborah Williams, Sue Murdock, Maryanne Ducey, Kerianne Nelson, Jason Block, James Mitchel, Connor G O’Brien, Sylvan Cox, William Marx, Ioana Amzuta, Asad J. Choudhry, Mohammad T. Azam, Kristina L Carter, Michael A Olmos, Brittany M Parker, Julio Quintanilla, Tara A Craig, Brendon J Clough, Jeffrey T Jameson, Utpal S. Bhalala, Joshua Kuehne, Melinda Garcia, Morgan Beebe, Heather Herrera, Chris Fiack, Stephanie Guo, May Vawer, Beth Blackburn, Caleb Darby, Kristy Page, Amanda Brown, Jessie McAbee, Katherine A. Belden, Michael Baram, Devin M. Weber, Rosalie DePaola, Yuwei Xia, Hudson Carter, Aaron Tolley, Mary Barletta, Mark Steele, Laurie Kemble, Joshua L. Denson, A. Scott Gillet, Margo Brown, Rachael Stevens, Andrew Wetherbie, Kevin Tea, Mathew Moore, Abdurrahman Husain, Atul Malhotra, Qais Zawaydeh, Benjamin J Sines, Thomas J Bice, Emily A. Vail, Susannah Nicholson, Rachelle B. Jonas, AnnaRose E. Dement, William Tang, Mark DeRosa, Robert E. Villarreal, Rajany V. Dy, Alfredo Iardino, Jill Sharma, Richard Czieki, Julia Christopher, Ryan Lacey, Marwan Mashina, Kushal Patel, Erica C. Bjornstad, Nancy M. Tofil, Scott House, Isabella Aldana, Nikhil K. Meena, Jose D. Caceres, Nikhil K Meena, Sarenthia M. Epps, Harmeen Goraya, Kelsey R. Besett, Ryan James, Lana Y. Abusalem, Akash K. Patel, Lana S Hasan, Dina Gomaa, Michael Goodman, Devin Wakefield, Anthony Spuzzillo, John O. Shinn II, Robert MacLaren, Azra Bihorac, Tezcan Ozrazgat Baslanti, George Omalay, Haleh Hashemighouchani, Julie S. Cupka, Matthew M Ruppert, Patrick W. McGonagill, Colette Galet, Janice Hubbard, David Wang, Lauren Allan, Aditya Badheka, Madhuradhar Chegondi, Usman Nazir, Garrett Rampon, Jake Riggle, Nathan Dismang, Vicki Montgomery, Janice Sullivan, Sarah Morris, Jennifer Nason, Ozan Akca, Rainer Lenhardt, Rodrigo S. Cavallazzi, Ann Jerde, Alexa Black, Allison Polidori, Haily Griffey, Justin Winkler, Thomas Brenzel, Roger A. Alvarez, Amarilys Alarcon-Calderon, Marie Anne Sosa, Sunita K. Mahabir, Mausam J. Patel, Pauline Park, Andrew Admon, Sinan Hanna, Rishi Chanderraj, Maria Pliakas, Ann Wolski, Jennifer Cirino, Dima Dandachi, Hariharan Regunath, Maraya N. Camazine, Grant. E. Geiger, Abdoulie O. Njai, Baraa M. Saad, Faraaz Ali Shah, Byron Chuan, Sagar L. Rawal, Manal Piracha, Joseph E. Tonna, Nicholas M. Levin, Kayte Suslavich, Rachel Tsolinas, Zachary T. Fica, Chloe R. Skidmore, Renee D. Stapleton, Anne E. Dixon, Olivia Johnson, Sara S. Ardren, Stephanie Burns, Anna Raymond, Erika Gonyaw, Kevin Hodgdon, Chloe Housenger, Benjamin Lin, Karen McQuesten, Heidi Pecott-Grimm, Julie Sweet, Sebastian Ventrone, Nita Khandelwal, T. Eoin West, Ellen S. Caldwell, Lara Lovelace-Macon, Navya Garimella, Denisse B. Dow, Sreekanth R. Cheruku, Catherine Chen, Murtaza Akhter, Rania Abdul Rahman, Mary Mulrow, Erin M. Wilfong, Kelsi Vela, Ashish K. Khanna, Lynne Harris, Bruce Cusson, Jacob Fowler, David Vaneenenaam, Glen McKinney, Imoh Udoh, Kathleen Johnson, Patrick G. Lyons, Andrew P Michelson, Sara S. Haluf, Lauren M. Lynch, Nguyet M. Nguyen, Aaron Steinberg, Nicholas Braus, Vishwanath Pattan, Jessica Papke, Ismail Jimada, Nida Mhid, Samuel Chakola, Kevin Sheth, Abdalla Ammar, Mahmoud Ammar, Victor Torres Lopez, Charles Dela Cruz,, Akhil Khosla, and Samir Gautam

Subjects
Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract

OBJECTIVES:. To describe the prevalence, associated risk factors, and outcomes of serious neurologic manifestations (encephalopathy, stroke, seizure, and meningitis/encephalitis) among patients hospitalized with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. DESIGN:. Prospective observational study. SETTING:. One hundred seventy-nine hospitals in 24 countries within the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study COVID-19 Registry. PATIENTS:. Hospitalized adults with laboratory-confirmed SARS-CoV-2 infection. INTERVENTIONS:. None. RESULTS:. Of 16,225 patients enrolled in the registry with hospital discharge status available, 2,092 (12.9%) developed serious neurologic manifestations including 1,656 (10.2%) with encephalopathy at admission, 331 (2.0%) with stroke, 243 (1.5%) with seizure, and 73 (0.5%) with meningitis/encephalitis at admission or during hospitalization. Patients with serious neurologic manifestations of COVID-19 were older with median (interquartile range) age 72 years (61.0–81.0 yr) versus 61 years (48.0–72.0 yr) and had higher prevalence of chronic medical conditions, including vascular risk factors. Adjusting for age, sex, and time since the onset of the pandemic, serious neurologic manifestations were associated with more severe disease (odds ratio [OR], 1.49; p < 0.001) as defined by the World Health Organization ordinal disease severity scale for COVID-19 infection. Patients with neurologic manifestations were more likely to be admitted to the ICU (OR, 1.45; p < 0.001) and require critical care interventions (extracorporeal membrane oxygenation: OR, 1.78; p = 0.009 and renal replacement therapy: OR, 1.99; p < 0.001). Hospital, ICU, and 28-day mortality for patients with neurologic manifestations was higher (OR, 1.51, 1.37, and 1.58; p < 0.001), and patients had fewer ICU-free, hospital-free, and ventilator-free days (estimated difference in days, –0.84, –1.34, and –0.84; p < 0.001). CONCLUSIONS:. Encephalopathy at admission is common in hospitalized patients with SARS-CoV-2 infection and is associated with worse outcomes. While serious neurologic manifestations including stroke, seizure, and meningitis/encephalitis were less common, all were associated with increased ICU support utilization, more severe disease, and worse outcomes.

Published
2022
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31. Variation in Sedative and Analgesic Use During the COVID-19 Pandemic and Associated Outcomes

Author

Rucci, Justin M., primary, Law, Anica C., additional, Bolesta, Scott, additional, Quinn, Emily K., additional, Garcia, Michael A., additional, Gajic, Ognjen, additional, Boman, Karen, additional, Yus, Santiago, additional, Goodspeed, Valerie M., additional, Kumar, Vishakha, additional, Kashyap, Rahul, additional, Walkey, Allan J., additional, Mesland, Jean-Baptiste, additional, Henin, Pierre, additional, Petre, Hélène, additional, Buelens, Isabelle, additional, Gerard, Anne-Catherine, additional, Markotić, Dragana, additional, Bošnjak, Ivana, additional, Garza, Ruben, additional, Chu, Eric, additional, Chan, Victoria, additional, Gavidia, Oscar Y., additional, Pachon, Felipe, additional, El Kassas, Mohamed, additional, Tawheed, Ahmed, additional, Matsuda, Wataru, additional, Itagaki, Yuki, additional, Kodate, Akira, additional, Suzuki, Reina, additional, Takahashi, Yuki, additional, Moriki, Koyo, additional, Amer, Marwa Ridha, additional, Bawazeer, Mohammed Abdullah, additional, Dahhan, Talal I., additional, Kseibi, Eiad, additional, Butt, Abid Shahzad, additional, Khurshid, Syed Moazzum, additional, Rabee, Muath, additional, Abujazar, Mohammed, additional, Alghunaim, Razan, additional, Abualkhair, Maal, additional, AlFirm, Abeer Turki, additional, Almazyad, Mohammed A., additional, Alarifi, Mohammed I., additional, Macarambon, Jara M., additional, Bukhari, Ahmad Abdullah, additional, Albahrani, Hussain A., additional, Asfina, Kazi N., additional, Aldossary, Kaltham M., additional, Bojicic, Jovana, additional, Kovacevic, Bojan, additional, Predrag, Stevanovic, additional, Stojakov, Dejan S., additional, Ignjatovic, Duska K., additional, Bojic, Suzana C., additional, Bobos, Marina M., additional, Nenadic, Irina B., additional, Zaric, Milica S., additional, Djuric, Marko D., additional, Djukic, Vladimir R., additional, Teruel, Santiago Y., additional, Martin, Belen C., additional, Kharbanda, Anmol, additional, Jhajhria, Sunil, additional, Fyffe, Zachary, additional, Capizzi, Stephen, additional, Alicie, Bethany, additional, Green, Martha, additional, Crockarell, Lori, additional, Drennan, Amelia, additional, Dubuque, Kathleen, additional, Fambrough, Tonya, additional, Gasaway, Nikole, additional, Krantz, Briana, additional, Nebi, Peiman, additional, Orga, Jan, additional, Serfass, Margaret, additional, Simion, Alina, additional, Warren, Kimberly, additional, Wheeler, Cassie, additional, Woolman, C.J., additional, Christie, Amy B., additional, Ashley, Dennis W., additional, Adiga, Rajani, additional, Newsome, Andrea Sikora, additional, Forehand, Christy C., additional, Bruning, Rebecca, additional, Jones, Timothy W., additional, Waikar, Sushrut S., additional, Colona, Mia, additional, Kibbelaar, Zoe, additional, Leong, Michael, additional, Wallman, Daniel, additional, Soni, Kanupriya, additional, Maccarone, Jennifer, additional, Gilman, Joshua, additional, Devis, Ycar, additional, Chung, Joseph, additional, Paracha, Munizay, additional, Lumelsky, David N., additional, DiLorenzo, Madeline, additional, Abdurrahman, Najla, additional, Johnson, Shelsey, additional, Tirupathi, Raghavendra, additional, Tang, Alymer, additional, Safi, Arshad, additional, Green, Cindy, additional, Newell, Jackie, additional, Ramani, Naga, additional, Ganti, Bhavani Harika, additional, Daugherty, Steven K., additional, Atkinson, Sam, additional, Shrimpton, Kelly, additional, Smalls, Norma, additional, Reilkoff, Ronald A., additional, Heneghan, Julia A., additional, Eichen, Sarah, additional, Goertzen, Lexie, additional, Rajala, Scott, additional, Feussom, Ghislaine, additional, Tang, Ben, additional, Cartin-Ceba, Rodrigo, additional, Sen, Ayan, additional, Talaei, Fahimeh, additional, Domecq, Juan Pablo, additional, Bansal, Vikas, additional, Tekin, Aysun, additional, Lal, Amos, additional, O'Horo, John C., additional, Deo, Neha N., additional, Sharma, Mayank, additional, Qamar, Shahraz, additional, Singh, Romil, additional, Valencia Morales, Diana J., additional, Sharma, Nikhil, additional, Khan, Syed Anjum, additional, Jain, Nitesh Kumar, additional, Koritala, Thoyaja, additional, Khedr, Anwar M., additional, Mushtaq, Hisham A., additional, Jama, Abbas B., additional, Venkata, Chakradhar, additional, Engemann, Miriam, additional, Mantese, Annamarie, additional, Aulakh, Bhagat S., additional, Tripathi, Sandeep, additional, Bandy, Jennifer A., additional, Kreps, Lisa M., additional, Bollinger, Dawn R., additional, Stienecker, Roger Scott, additional, Melendez, Andre G., additional, Brunner, Tressa A., additional, Budzon, Sue M., additional, Heffernan, Jessica L., additional, Souder, Janelle M., additional, Miller, Tracy L., additional, Maisonneuve, Andrea G., additional, Vilella, Antonia L., additional, Kutner, Sara B., additional, Clark, Kacie, additional, Moore, Danielle, additional, Zaren, Howard A., additional, Smith, Stephanie J., additional, Lewis, Grant C., additional, Seames, Lauren, additional, Farlow, Cheryl, additional, Miller, Judy, additional, Broadstreet, Gloria, additional, Martinez, Anthony, additional, Allison, Micheal, additional, Mittal, Aniket, additional, Ruiz, Rafael, additional, Skaanland, Aleta, additional, Ross, Robert, additional, Bernstein, Michael A., additional, Goff, Ian K., additional, Naftilan, Matthew, additional, Mathew, Amal, additional, Williams, Deborah, additional, Murdock, Sue, additional, Ducey, Maryanne, additional, Nelson, Kerianne, additional, Gupta, Neha, additional, Jones, Tracy L., additional, Ayers, Shonda C., additional, Harrell, Amy B., additional, Brown, Brent R., additional, Malone, Kassidy, additional, Sinko, Lauren A., additional, Settle, Lisa M., additional, Sears, Taylor J., additional, McGonagill, Patrick W., additional, Galet, Colette, additional, Hubbard, Janice, additional, Wang, David, additional, Allan, Lauren, additional, Badheka, Aditya, additional, Chegondi, Madhuradhar, additional, Stapleton, Renee D., additional, Dixon, Anne E., additional, Johnson, Olivia, additional, Ardren, Sara S., additional, Burns, Stephanie, additional, Raymond, Anna, additional, Gonyaw, Erika, additional, Hodgdon, Kevin, additional, Housenger, Chloe, additional, Lin, Benjamin, additional, McQuesten, Karen, additional, Pecott-Grimm, Heidi, additional, Sweet, Julie, additional, Ventrone, Sebastian, additional, Khanna, Ashish K., additional, Harris, Lynnette, additional, Cusson, Bruce, additional, Reeves, Brandon, additional, Fanelli, Jessica, additional, Disher, Nataya, additional, Samant, Anusha, additional, DeGroot, Chritian, additional, Youshock, Evan, additional, Ligon, R. Miller, additional, McCartney, Katherine, additional, Garcia, Julio, additional, Iloabachie, Chidi, additional, Flores, Kelsey, additional, VanEenenaam, David, additional, Sands, Lauren, additional, Robinson, Samuel, additional, Sweatt, Nia, additional, Fowler, Jacob, additional, Fram, Madeline, additional, Howard, Easton, additional, Johnson, Kathleen, additional, Udoh, Imoh, additional, Nosow, Lillian, additional, Howard, Lucy Winesett, additional, Minh Pham, Quan Duc, additional, Irfanullah, Aman, additional, Ong, Tiffany, additional, Enwezor, Chukwunyelu Henry, additional, Dabagian, Hannah, additional, and Mendoza, Rafael, additional

Published
2024
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32. Developing a core outcome set for the health outcomes for children and adults with congenital oesophageal atresia and/or tracheo-oesophageal fistula: OCELOT task group study protocol

Author

Ducey, Jonathan, primary, Lansdale, Nick, additional, Gorst, Sarah, additional, Bray, Lucy, additional, Teunissen, Nadine, additional, Cullis, Paul, additional, Faulkner, Julia, additional, Gray, Victoria, additional, Gutierrez Gammino, Lucia, additional, Slater, Graham, additional, Baird, Laura, additional, Adams, Alex, additional, Brendel, Julia, additional, Donne, Adam, additional, Folaranmi, Eniola, additional, Hopwood, Laura, additional, Long, Anna-May, additional, Losty, Paul D, additional, Benscoter, Dan, additional, de Vos, Corné, additional, King, Sebastian, additional, Kovesi, Tom, additional, Krishnan, Usha, additional, Nah, Shireen A, additional, Ong, Lin Yin, additional, Rutter, Mike, additional, Teague, Warwick J, additional, Zorn, Aaron M, additional, Hall, Nigel J, additional, and Thursfield, Rebecca, additional

Published
2024
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35. Integer invariants of abelian Cayley graphs

Author

Ducey, Joshua E. and Jalil, Deelan M.

Subjects
Mathematics - Combinatorics, Mathematics - Spectral Theory, 05C50
Abstract

Let $G$ be a finite abelian group, let $E$ be a subset of $G$, and form the Cayley (directed) graph of $G$ with connecting set $E$. We explain how, for various matrices associated to this graph, the spectrum can be used to give information on the Smith normal form. This technique is applied to several interesting examples, including matrices in the Bose-Mesner algebra of the Hamming association scheme $H(n,q)$. We also recover results of Bai and Jacobson-Niedermaier-Reiner on the critical group of a Cartesian product of complete graphs., Comment: 8 pages. Many small changes, mostly to make references more precise and to explain notation and terminology. The biggest changes are to Section 3, where we are now more careful with the statements of the theorems and their proofs

Published
2013

36. 10 Tips for Turning DI Theory into Practice

Author

Ducey, Melissa N. and Key, Shirley

Abstract

At the core of differentiated instruction (DI) is the belief that because all children are different, their learning needs and abilities are different, and therefore must be approached differently. Differentiating instruction allows teachers to meet the students where they are academically and bring them forward. Although one continues to grow in the use of DI, things are learned along the way that help take the theory of DI into practice for the classroom teacher: 1) DI can extend learning beyond the standards, 2) use open-ended (divergent) questions/problems, 3) start with tiered instruction, 4) grade on learning and growth, not a knowledge checklist, 5) remember that DI can be used to help even the best and brightest, 6) be proactive, not reactive to student needs, 7) incorporate option charts and "menus," 8) avoid the common pitfalls of microdifferentation, 9) maximize meaningful, but flexible, grouping, and 10) do not expect an overnight revolution. The goal in implementing DI was to increase student performance in physics. Through the use of DI, students were more receptive to working in groups, working at their own pace, working on application-based problems, and a noticed increase in students' desire to learn.

Published
2009

37. Integer invariants of an incidence matrix related to Rota's basis conjecture

Author

Bittner, Stephanie, Ducey, Joshua, Guo, Xuyi, Oh, Minah, and Zweber, Adam

Subjects
Mathematics - Combinatorics, 05B20, 05C50
Abstract

We compute the spectrum and Smith normal form of the incidence matrix of disjoint transversals, a combinatorial object closely related to the n-dimensional case of Rota's basis conjecture., Comment: v2. Minor changes, added a reference

Published
2013

39. The Elementary Divisors of the Incidence Matrix of Skew Lines in PG(3,q)

Author

Brouwer, Andries E., Ducey, Joshua E., and Sin, Peter

Subjects
Mathematics - Combinatorics, Mathematics - Group Theory, 05B20, 05E30 (Primary) 20C33, 51E20 (Secondary)
Abstract

The elementary divisors of the incidence matrix of lines in PG(3,q) are computed, where two lines are incident if and only if they are skew., Comment: 13 pages. The results of this paper supersede those in the paper arXiv:math/1001.2551 V2. Minor corrections

Published
2011

40. Risk Factors for Critical Coronavirus Disease 2019 and Mortality in Hospitalized Young Adults: An Analysis of the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS) Coronavirus Disease 2019 Registry

Author

Sandeep Tripathi, MD, MS, Imran A. Sayed, MD, Heda Dapul, MD, Jeremy S. McGarvey, MS, Jennifer A. Bandy, RN, Karen Boman, BS, Vishakha K. Kumar, MD, MBA, Vikas Bansal, MBBS, MPH, Lynn Retford, CAE, Sreekanth Cheruku, MD, MPH, Margit Kaufman, MD, FASA, Smith F. Heavner, MS, RN, Valerie C. Danesh, PhD, RN, Catherine A. St. Hill, DVM, PhD, Ashish K. Khanna, MD, Utpal Bhalala, MD, Rahul Kashyap, MBBS, MBA, Ognjen Gajic, MD, MS, Allan J. Walkey, MD, MS, Katja M. Gist, DO, MSc, for The Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS): COVID-19 Registry Investigator Group, Jean-Baptiste Mesland, Pierre Henin, Hélène Petre, Isabelle Buelens, Anne-Catherine Gerard, Philippe Clevenbergh, Rolando Claure-Del Granado, Jose A. Mercado, Esdenka Vega-Terrazas, Maria F. Iturricha-Caceres, Ruben Garza, Eric Chu, Victoria Chan, Oscar Y Gavidia, Felipe Pachon, Yeimy A Sanchez, Mohamed El Kassas, Mohamed Badr, Ahmed Tawheed, Hend Yahia, Sierra-Hoffman, Fernando Valerio, Oscar Diaz, Jose Luis Ramos Coello, Guillermo Perez, Ana Karen Vallecillo Lizardo, Gabina María Reyes Guillen, Helin Archaga Soto, Mradul Kumar Daga, Munisha Agarwal, Ishan Rohtagi, Anusha Cherian, Sreejith Parameswaran, Magesh Parthiban, Menu Priya A., Girish Vadgaonkar, Rekha Ediga, Shilpa Basety, Shwetha Dammareddy, Phani Sreeharsha Kasumalla, Sridhar Papani, Mahesh Kamuram, Smitha S. Segu, Tuhin Chakraborty, Epcebha Joyce, Umamaheswara Raju, Janaki Manduva, Naresh Kolakani, Shreeja Sripathi, Sheetal Chaitanya, Surapaneni Krishna Mohan, Ekambaram Jyothisree, Kamlesh Kumar Agrawal, Vijendra Baghel, Kirti Kumar Patel, Nooshin Dalili, Mohsen Nafa, Sandeep Tripathi, Yuki Itagaki, Akira Kodate, Reina Suzuki, Yuki Takahashi, Koyo Moriki, Michihito Kyo, Masamitsu Sanui, Sho Horikita, Wataru Matsuda, Shu Tahara, Mineji Hayakawa, Kunihiko Maekawa, Takuya Shiga, Yudai Iwasaki, Abdulrahman AlFares, Rene Rodriguez-Gutierrez, Jose Gerardo Gonzalez-Gonzalez, Alejandro Salcido-Montenegro, Adrian Camacho-Ortiz, Fatimah Hassan-Hanga, Hadiza Galadanci, Abubakar Shehu Gezawa, Halima M. S. Kabara, Taiwo Gboluwaga Amole, Halima Kabir, Dalha Gwarzo, Haliru, Abdullahi S Ibrahim, Muhammad Sohaib Asghar, Mashaal Syed, Syed Anosh Ali Naqvi, Igor Borisovich Zabolotskikh, Konstantin Dmitrievich Zybin, Sergey Vasilevich Sinkov, Tatiana Sergeevna Musaeva, Marwa Ridha Amer, Mohammed Abdullah Bawazeer, Talal I. Dahhan, Eiad Kseibi, Abid Shahzad Butt, Syed Moazzum Khurshid, Muath Rabee, Mohammed Abujazar, Razan Alghunaim, Maal Abualkhair, Abeer Turki AlFirm, Razan K Alamoudi, Hassan M. AlSharif, Sarah A. Almazwaghi, Mohammed S Elsakran, Mohamed A Aid, Mouaz A Darwich, Omnia M Hagag, Salah A Ali, Alona rocacorba, Kathrine Supeña, Efren Ray Juane, Jenalyn Medina, Jowany Baduria, Mohammed A Almazyad, Mohammed I Alarifi, Jara M Macarambon, Ahmad Abdullah Bukhari, Hussain A. Albahrani, Kazi N Asfina, Kaltham M Aldossary, Predrag D Stevanovic, Dejan S Stojakov, Duska K Ignjatovic, Suzana C Bojic, Marina M Bobos, Irina B Nenadic, Milica S Zaric, Marko D Djuric, Vladimir R Djukic, Bojan Kovacevic, Jovana Bojicic, Marija Zdravkovic, Zoran Todorovic, Viseslav Popadic, Slobodan Klasnja, Santiago Y. Teruel, Belen C. Martin, Himat Sulaimonov, Firuza Khudonazarova, Nabi Bakhtibekov, Nekruz Jamshedov, Uluhan Sili, Huseyin Bilgin, Pinar Ay, Varsha P Gharpure, Usman Raheemi, Kenneth W. Dodd, Nicholas Goodmanson, Kathleen Hesse, Paige Bird, Chauncey Weinert, Nathan Schoenrade, Abdulrahman Altaher, Esmael Mayar, Matthew Aronson, Tyler Cooper, Monica Logan, Brianna Miner, Gisele Papo, Eric M. Siegal, Phyllis Runningen, Catherine A. St. Hill, Roman R. Melamed, David M. Tierney, Love A. Patel, Vino S. Raj, Barite U. Dawud, Narayana Mazumder, Abbey Sidebottom, Alena M. Guenther, Benjamin D. Krehbiel, Nova J. Schmitz, Stacy L. Jepsen, Abhijit A Raval, Andrea Franks, Katherine Irby, Ronald C. Sanders, Jr., Glenda Hefley, Anmol Kharbanda, Sunil Jhajhria, Zachary Fyffe, Stephen Capizzi, Bethany Alicie, Martha Green, Lori Crockarell, Amelia Drennan, Kathleen Dubuque, Tonya Fambrough, Nikole Gasaway, Briana Krantz, Peiman Nebi, Jan Orga, Margaret Serfass, Alina Simion, Kimberly Warren, Cassie Wheeler, CJ Woolman, Andrew S. Moyer, George M. Verghese, Andrea Sikora Newsome, Christy C. Forehand, Rebecca Bruning, Timothy W. Jones, Moldovan Sabov, Fatema Zaidi, Fiona Tissavirasingham, Dhatri Malipeddi, Jarrod M Mosier, Karen Lutrick, Beth Salvagio Campbell, Cathleen Wilson, Patrick Rivers, Jonathan Brinks, Mokenge Ndiva Mongoh, Boris Gilson, Donna Lee Armaignac, Don Parris, Maria Pilar Zuniga, Ilea Vargas, Viviana Boronat, Anneka Hutton, Navneet Kaur, Prashank Neupane, Nohemi Sadule-Rios, Lourdes M. Rojas, Aashish Neupane, Priscilla Rivera, Carlos Valle Carlos, Gregory Vincent, Mahesh Amin, Mary E Schelle, Amanda Steadham, Christopher M Howard, Cameron McBride, Jocelyn Abraham, Orlando Garner, Katherine Richards, Keegan Collins, Preethi Antony, Sindhu Mathew, Valerie C. Danesh, Gueorgui Dubrocq, Amber L. Davis, Marissa J Hammers, ill M. McGahey, Amanda C. Farris, Elisa Priest, Robyn Korsmo, Lorie Fares, Kathy Skiles, Susan M. Shor, Kenya Burns, Corrie A Dowell, Melody Flores, Lindsay Newman, Debora A Wilk, Jason Ettlinger, Jaccallene Bomar, Himani Darji, Alejandro Arroliga, Alejandro C Arroliga, Corrie A. Dowell, Gabriela Hope Conzales, Debora A. Wilk, Paras B. Khandhar, Elizabeth Kring, Valerie M. Banner-Goodspeed, Somnath Bose, Lauren E. Kelly, Melisa Joseph, Marie McGourty, Krystal Capers, Benjamin Hoenig, Maria C. Karamourtopoulos, Anica C. Law, Elias N. Baedorf Kassis, Allan J. Walkey, Sushrut S. Waikar, Michael A. Garcia, Mia Colona, Zoe Kibbelaar, Michael Leong, Daniel Wallman, Kanupriya Soni, Jennifer Maccarone, Joshua Gilman, Ycar Devis, Joseph Chung, Munizay Paracha, David N. Lumelsky, Madeline DiLorenzo, Najla Abdurrahman, Shelsey Johnson, Andrew M. Hersh, Stephanie L Wachs, Brittany S. Swigger, Lauren A. Sattler, Michael N. Moulton, Kimberly Zammit, J Patrick, William McGrath, Maya Loeffler, R Chilbert, Aaron S. Miller, Edwin L. Anderson, Rosemary Nagy, Ravali R. Inja, Raghavendra Tirupathi, Alymer Tang, Arshad Safi, Cindy Green, Jackie Newell, Rayan E. Ihle, Shelda A. Martin, Elaine A. Davis, Katja M. Gist, Imran A Sayed, John Brinton, Larisa Strom, Kathleen Chiotos, Allison M. Blatz, Giyoung Lee, Ryan H. Burnett, Guy I. Sydney, Danielle M. Traynor, Karissa Nauert, Annika Gonzalez, Mariel Bagley, Anita Santpurkar, Salim Surani, Joshua White, Aftab Khan, Rahul Dhahwal, Sreekanth Cheruku, Farzin Ahmed, Christopher Deonarine, Ashley Jones, Mohammad-Ali Shaikh, David Preston, Jeanette Chin, Vidula Vachharajani, Abhijit Duggal, Prabalini Rajendram, Omar Mehkri, Siddharth Dugar, Michelle Biehl, Gretchen Sacha, Stuart Houltham, Alexander King, Kiran Ashok, Bryan Poynter, Mary Beukemann, Richard Rice, Susan Gole, Valerie Shaner, Adarsh Conjeevaram, Michelle Ferrari, Narendrakumar Alappan, Steven Minear, Jaime Hernandez-Montfort, Syed Sohaib Nasim, Ravi Sunderkrishnan, Debasis Sahoo, Patrick S. Milligan, Sandeep K. Gupta, Joy M. Koglin, Regina Gibson, Lana Johnson, Felicia Preston, Crimson Scott, Bethany Nungester, Steven K. Daugherty, Sam Atkinson, Kelly Shrimpton, Sidney Ontai, Brian Contreras, Uzoma Obinwanko, Nneka Amamasi, Amir Sharafi, Sarah Lee, Zahia Esber, Chetna Jinjvadia, Kimberly Welker, Francis M. Maguire, Jessica Timmer, Raquel R Bartz, Vijay Krishnamoorthy, Bryan Kraft, Aaron Pulsipher, Eugene Friedman, Sachin Mehta, Margit Kaufman, Gregg Lobel, Nisha Gandhi, Amr Abdelaty, Elizabeth Shaji, Kiana Lim, Juan Marte, Dani Ashley Sosa, David P. Yamane, Ivy Benjenk, Nivedita Prasanna, Smith F. Heavner-Sullivan, Prera J. Roth, Banu Sivaraj, Haley Fulton, Madison G Herin, Marissa Crum, Morgan E. Fretwell, Emily-Rose Zhou, Christine Waller, Kara Kallies, Jonean Thorsen, Alec Fitzsimmons, Haley Olsen, Heda R. Dapul, Sourabh Verma, Alan Salas, Ariel Daube, Michelle Korn, Michelle Ramirez, Logi Rajagopalan, Laura Santos, Orma Smalls, Atul Malhotra, Abdurrahman Husain, Qais Zawaydeh, J.H. Steuernagle, Steven Q. Davis, Valentina Jovic, Max Masuda, Amanda Hayes, Katharine Nault, Michael Smith, William Snow, Riley Liptak, Hannah Durant, Valerie Pendleton, Alay Nanavati, Risa Mrozowsk, LiManoj K Gupta, Franscene E. Oulds, Akshay Nandavar, Yuk Ming Liu, Sarah Zavala, Esther Shim, Ronald A. Reilkoff, Julia A. Heneghan, Sarah Eichen, Lexie Goertzen, Scott Rajala, Ghislaine Feussom, Ben Tang, Christine C. Junia, Robert Lichtenberg, Hasrat Sidhu, Diana Espinoza, Shelden Rodrigues, Maria Jose Zabala, Daniela Goyes, Ammu Susheela, Buddhi Hatharaliyadda, Naveen Rameshkumar, Amulya Kasireddy, Genessis Maldonado, Lisseth Beltran, Akshata Chaugule, Hassan Khan, Namrata Patil, Ruhi Patil, Rodrigo Cartin-Ceba, Ayan Sen, Amanda Palacios, Giyth M. Mahdi, Rahul Kashyap, Ognjen Gajic, Vikas Bansal, Aysun Tekin, Amos Lal, John C. O’Horo, Neha N. Deo, Mayank Sharma, Shahraz Qamar, Cory J. Kudrna, Juan Pablo Domecq Garces, Abigail T. La Nou, Marija Bogojevic, Devang Sanghavi, Pramod Guru, Karthik Gnanapandithan, Hollie Saunders, Zachary Fleissner, Juan Garcia, Alejandra Yu Lee Mateus, Siva Naga Yarrarapu, Syed Anjum Khan, Juan Pablo Domecq, Nitesh Kumar Jain, Thoyaja Koritala, Alexander Bastidas, Gabriela Orellana, Adriana Briceno Bierwirth, Eliana Milazzo, Juan Guillermo Sierra, Thao Dang, Amy B. Christie, Dennis W. Ashley, Rajani Adiga, Rahul S Nanchal, Paul A Bergl, Jennifer L Peterson, Travis Yamanaka, Nicholas A. Barreras, Michael Markos, Anita Fareeduddin, Rohan Mehta, Chakradhar Venkata, Miriam Engemann, Annamarie Mantese, Yasir Tarabichi, Adam Perzynski, Christine Wang, Dhatri Kotekal, Adriana C Briceno Bierwirth, Gabriela M Orellana, Gerardo Catalasan, Shohana Ahmed, Carlos F Matute, Ahmad Hamdan, Ivania Salinas, Genesis Del Nogal, Angel Tejada, Anna Eschler, Mary Hejna, Emily Lewandowski, Kristen Kusmierski, Clare Martin, Jen-Ting Chen, Aluko Hope, Zoe Tsagaris, Elise Ruen, Aram Hambardzumyan, Prithvi Sendi, Meghana Nadiger, Balagangadhar Totapally, Bhagat S. Aulakh, Jennifer A. Bandy, Lisa M. Kreps, Dawn R. Bollinger, Roger Scott Stienecker, Andre G. Melendez, Tressa A. Brunner, Sue M Budzon, Jessica L. Heffernan, Janelle M. Souder, Tracy L. Miller, Andrea G. Maisonneuve, Roberta E. Redfern, Jessica Shoemaker, Jennifer Micham, Lynn Kenney, Gabriel Naimy, Sara Utley, Holly Balcer, Kerry P. J. Pulver, Jennifer Yehle, Alicia Weeks, Terra Inman, Brian L. Delmonaco, Anthony Franklin, Mitchell Heath, Antonia L. Vilella, Sara B. Kutner, Kacie Clark, Danielle Moore, Shina Menon, John K McGuire, Deana Rich, Harry L. Anderson, III, Dixy Rajkumar, Ali Abunayla, Jerrilyn Heiter, Howard A. Zaren, Stephanie J. Smith, Grant C. Lewis, Lauren Seames, Cheryl Farlow, Judy Miller, Gloria Broadstreet, John Lin, Cindy Terrill, Brock Montgomery, Sydney Reyes, Summer Reyes, Alex Plattner, Anthony Martinez, Micheal Allison, Aniket Mittal, Rafael Ruiz, Aleta Skaanland, Robert Ross, Umang Patel, Jordesha Hodge, KrunalKumar Patel, Shivani Dalal, Himanshu Kavani, Sam Joseph, Michael A. Bernstein, Ian K. Goff, Matthew Naftilan, Amal Mathew, Deborah Williams, Sue Murdock, Maryanne Ducey, Kerianne Nelson, Paul K Mohabir, Connor G O’Brien, Komal Dasani, William Marx, Ioana Amzuta, Asad J. Choudhry, Mohammad T. Azam, Kristina L Carter, Michael A Olmos, Brittany M Parker, Julio Quintanilla, Tara A Craig, Brendon J Clough, Jeffrey T Jameson, Neha Gupta, Tracy L Jones, Shonda C Ayers, Amy B Harrell, Dr.Brent R Brown, Utpal S. Bhalala, Joshua Kuehne, Melinda Garcia, Morgan Beebe, Heather Herrera, Chris Fiack, Stephanie Guo, May Vawer, Beth Blackburn, Megan Edwards, Caleb Darby, Kristy Page, Amanda Brown, Jessie McAbee, Katherine A. Belden, Michael Baram, Devin M. Weber, Rosalie DePaola, Yuwei Xia, Hudson Carter, Aaron Tolley, Mark Steele, Laurie Kemble, Joshua L. Denson, A. Scott Gillet, Margo Brown, Rachael Stevens, Andrew Wetherbie, Kevin Tea, Mathew Moore, Benjamin J Sines, Thomas J Bice, Emily A. Vail, Susannah Nicholson, Rachelle B. Jonas, AnnaRose E. Dement, William Tang, Mark DeRosa, Robert E. Villarreal, Rajany V. Dy, Alfredo Iardino, Jill Sharma, Richard Czieki, Julia Christopher, Ryan Lacey, Marwan Mashina, Kushal Patel, Erica C. Bjornstad, Nancy M. Tofil, Scott House, Isabella Aldana, Nikhil K. Meena, Jose D. Caceres, Nikhil K Meena, Sarenthia M. Epps, Harmeen Goraya, Kelsey R. Besett, Ryan James, Lana Y. Abusalem, Akash K. Patel, Lana S Hasan, Dina Gomaa, Michael Goodman, Devin Wakefield, Anthony Spuzzillo, John O. Shinn, II, Azra Bihorac, Tezcan Ozrazgat Baslanti, George Omalay, Haleh Hashemighouchani, Julie S. Cupka, Matthew M Ruppert, Patrick W. McGonagill, Colette Galet, Janice Hubbard, David Wang, Lauren Allan, Aditya Badheka, Madhuradhar Chegondi, Usman Nazir, Garrett Rampon, Jake Riggle, Nathan Dismang, Vicki Montgomery, Janice Sullivan, Sarah Morris, Jennifer Nason, Roger A. Alvarez, Amarilys Alarcon-Calderon, Marie Anne Sosa, Sunita K. Mahabir, Mausam J. Patel, Pauline Park, Andrew Admon, Sinan Hanna, Rishi Chanderraj, Maria Pliakas, Ann Wolski, Jennifer Cirino, Dima Dandachi, Hariharan Regunath, Maraya N. Camazine, Grant. E. Geiger, Abdoulie O. Njai, Baraa M. Saad, Faraaz Ali Shah, Byron Chuan, Sagar L. Rawal, Manal Piracha, Joseph E. Tonna, Nicholas M. Levin, Kayte Suslavich, Rachel Tsolinas, Zachary T. Fica, Chloe R. Skidmore, Renee D. Stapleton, Anne E. Dixon, Olivia Johnson, Sara S. Ardren, Stephanie Burns, Anna Raymond, Erika Gonyaw, Kevin Hodgdon, Chloe Housenger, Benjamin Lin, Karen McQuesten, Heidi Pecott-Grimm, Julie Sweet, Sebastian Ventrone, Nita Khandelwal, T. Eoin West, Ellen S. Caldwell, Lara Lovelace-Macon, Navya Garimella, Denisse B. Dow, Murtaza Akhter, Rania Abdul Rahman, Mary Mulrow, Erin M. Wilfong, Kelsi Vela, Ashish K. Khanna, Lynne Harris, Bruce Cusson, Jacob Fowler, David Vaneenenaam, Glen McKinney, Imoh Udoh, Kathleen Johnson, Patrick G. Lyons, Andrew P Michelson, Sara S. Haluf, Lauren M. Lynch, Nguyet M. Nguyen, Aaron Steinberg, Nicholas Braus, Vishwanath Pattan, Jessica Papke, Ismail Jimada, Nida Mhid, and Samuel Chakola

Subjects
Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract

IMPORTANCE:. Even with its proclivity for older age, coronavirus disease 2019 has been shown to affect all age groups. However, there remains a lack of research focused primarily on the young adult population. OBJECTIVES:. To describe the epidemiology and outcomes of coronavirus disease 2019 and identify the risk factors associated with critical illness and mortality in hospitalized young adults. DESIGN, SETTINGS, AND PARTICIPANTS:. A retrospective cohort study of the Society of Critical Care Medicine’s Viral Infection and Respiratory Illness Universal Study registry. Patients 18–40 years old, hospitalized from coronavirus disease 2019 from March 2020 to April 2021, were included in the analysis. MAIN OUTCOMES AND MEASURES:. Critical illness was defined as a composite of mortality and 21 predefined interventions and complications. Multivariable logistic regression was used to assess associations with critical illness and mortality. RESULTS:. Data from 4,005 patients (152 centers, 19 countries, 18.6% non-U.S. patients) were analyzed. The median age was 32 years (interquartile range, 27–37 yr); 51% were female, 29.4% Hispanic, and 42.9% had obesity. Most patients (63.2%) had comorbidities, the most common being hypertension (14.5%) and diabetes (13.7%). Hospital and ICU mortality were 3.2% (129/4,005) and 8.3% (109/1,313), respectively. Critical illness occurred in 25% (n = 996), and 34.3% (n = 1,376) were admitted to the ICU. Older age (p = 0.03), male sex (adjusted odds ratio, 1.83 [95% CI, 1.2–2.6]), and obesity (adjusted odds ratio, 1.6 [95% CI, 1.1–2.4]) were associated with hospital mortality. In addition to the above factors, the presence of any comorbidity was associated with critical illness from coronavirus disease 2019. Multiple sensitivity analyses, including analysis with U.S. patients only and patients admitted to high-volume sites, showed similar risk factors. CONCLUSIONS:. Among hospitalized young adults, obese males with comorbidities are at higher risk of developing critical illness or dying from coronavirus disease 2019.

Published
2021
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41. The Elementary Divisors of the Incidence Matrices of Skew Lines in PG(3,p)

Author

Ducey, Joshua and Sin, Peter

Subjects
Mathematics - Combinatorics, Mathematics - Representation Theory, 05B20, 05E18, 20C33
Abstract

The elementary divisors of the incidence matrices of lines in $PG(3,p)$ are computed, where two lines are incident if and only if they are skew., Comment: 9 pages

Published
2010

45. Early years postgraduate surgical training programmes in the UK are failing to meet national quality standards: An analysis from the ASiT/BOTA Lost Tribe prospective cohort study of 2,569 surgical trainees

Author

Glasbey, James C., Harries, Rhiannon L., Beamish, Andrew J., Gokani, Vimal J., Mohan, Helen, Williams, Adam P., Fleming, Simon, Chai, Aaron, Singh, Abhinav, Stoneham, Adam C.S., Lunt, Adam J., Rehman, Adeeb H., Dhahri, Adeel A., Yvon, Adrien R.A., Dutta, Agneish, Abou-Foul, Ahmad K., Abdelrahman, Ahmed, Daoub, Ahmed, Sanalla, Ahmed, de Gea Rico, Aitor, Konarski, Alastair, Ward, Alex E., Wilkin, Alex J., Winter, Alexandra K., Arnaout, Ali, Bakhsh, Ali, Esfandiari, Alireza, Hardy, Alistair W., Khan, Amad N., Thacoor, Amitabh, Gavrila, Ana D., Nedea, Anca-Mihaela, Fontalis, Andreas, Hall, Andrew J., Williamson, Andrew J., Kosti, Angeliki, Harlinska, Anna, Adimonye, Anthony, Egglestone, Anthony, Thaventhiran, Anthony J., Myatt, Antonia, Vusirikala, Anuhya, Rawashdeh, Arab S., Paramasivan, Arjun C., Cotton, Arthur E., Scrimshire, Ashley B., Ramesh, Ashwanth C., Krishnamoorthy, Ashwin K., Ahmed, Asif, Abdul-Hamid, Ayeshah, Khan, Ayushah, Oremule, Babatunde, Ho, Beatrice, Barkham, Ben, Collard, Ben, Edgar, Ben F., Drake, Benjamin, John, Bethan E., Gordon, Catherine R., Rossborough, Catherine, Park, Chang Y., Seretis, Charalampos, Johnson, Charles H.N., Gill, Charn, Serino, Chiara, Ogbuokiri, Chinomso I., Swords, Chloe, Kang, Chong Y., McKinnon, Chris, Brown, Christopher E., Manning, Christopher J., Marusza, Christopher J., Jones, Christopher P., Forde, Cillian T., Wilson, Claire L., Koh, Claudia, Horgan, Conal, Lin, Daniel J., Ashmore, Daniel L., Ness, Daniel, Akhtar, Daniel O., Doherty, Daniel T., Scholfield, Daniel W., Ensor, David C., Bratt, David G., Spence, David J.R., Thomson, David R., Ferguson, David W., Apparau, Denish, Navaratnam, Devaraj M., Mai, Dinh, Rutherford, Duncan G., Karam, Edward, Wu, Eiling, Zimmermann, Eleanor F., Douka, Eleftheria, Flatt, Elinor, Kane, Elizabeth G., Thornhill, Elizabeth L., Gammeri, Emanuele, Littlehales, Emma G., Valsamis, Epaminondas M., Hankin, Erin J., Meenan, Erin R.M., Botha, Etienne N., Khalid, Farhan, Patel, Fatema, Power, Fiachra R., Rutherford, Fiona M., Saeed, Fozia, Guest, Francesca L., Barbosa, Francisco J., Cameron, Fraser G., Raja, Furqan R., Thiruchandran, Gajendiran, Munbauhal, Gavish, Dovey, Gemma E., Hogg, Gemma E., Dovell, George E., Matheron, George, Hill, George T., Layton, Georgia R., Jong, Georgiana G.S., Hicks, Georgina, Millward, Graham J., Shaw, Grahame A., Stamp, Gregory F.W., Parwaiz, Hammad, Chong, Han Hong, Copley, Hannah C., Lennox-Warburton, Hannah C., Emerson, Hannah M., Dean, Harry F., Eltyeb, Hazim, Chu, Howard O., Sadien, Iannish, Mohamed, Imran M., Parwaiz, Iram, Drummond, Isabella M.H., Pearce, Jack C.H., Ahmed, Jacob J., Koris, Jacob, Rait, Jaideep S., Bailey, James A., Cohen, James A., Kennedy, James A., Olivier, James B., Bailey, James, Archer, James E., Stewart, James J., de Barros, James N.J.Monteiro, Allen, James R., O'Brien, James W., James, McGhee, T., Quarcoopome, Jared N., Winyard, Jasmine C., Roberts, Jason L., Barwell, Jennifer S., Rodrigues, Jeremy, Chapman, Jessica A.R., Fairbanks, Jessica Y., Voll, Jessika, Lim, Jie Q., Chang, Jin H., Bovis, Joanna L., Ferns, John, Tam, Johnson Pok Him, Herron, Jonathan B.T., Macdonald, Jonathan D.R., Ducey, Jonathan R., DIxon, Joseph W., Luck, Joshua T., Hewage, Kalon, Yakoub, Kamal M., Bhopal, Kamran F., Vejsbjerg, Karen A., Aboelmagd, Karim, Bera, Katarzyna D., Hamlett, Katharine E., Fok, Katherine E., Hurst, Katherine V., Gillams, Kathryn L., Siggens, Katie L., Young, Katie, Burns, Kenneth M., Burke, Kerry A., Seebah, Kevin, Shah, Khalid A., Bentick, Kieran R., Majid, Kiran, Davies, Kirsty L., Tan, Krystal, Baryeh, Kwaku W., Phillips, Laura A.F., Ellerton, Laura N., Giet, Leeying J., Monaghan, Liam, Ka Cheung, Lok, Shen, Louise L., Paramore, Louise, Arrowsmith, Lucy J., Attwell, Lukas A., Thornton, Luke, Xu, Luting, Leadon, Madeline L., Natarajan, Madhavi, Houlihan, Maria C.R., Cheah, Marisa, Sagmeister, Markus L., Abubakar, Maryam, Flynn, Matthew F., Harris, Matthew, Stone, Matthew J., Young, Matthew J., Gray, Matthew P., Horner, Matthew P., Schembri, Matthew, Trail, Matthew, Joy, Melvin, Rice, Michael J., Thomas, Michael P., Poon, Michael T.C., Stoddart, Michael T., Fong, Michelle L., Foster, Mitchell T., Mohamud, Mohamed F., Hoque, Mohammed N., Remtulla, Mohammedabbas, Javed Karim, Mohsin, Rezacova, Monika, Siddiqui, Muhammad B., Iqbal, Muhammad R., Mensa, Mussa, McCauley, Nadine, Bauer, Natasha J., Walker, Nathan, Hakim, Navid A., Knight, Ngonidzashe, O'Hara, Niall, Fawcett, Nicholas A., Wong, Nicholas, Allen, Nicola F.D., Husnoo, Nilofer, Vallabh, Nimisha, Srikandarajah, Nisaharan, Chidumije, Nnaemeka, Elamin, Obaiy, Akinlaja, Odunayo O., Griffiths, Olga, Brown, Oliver D., Shastri, Oliver, Cameron, Olivia J., Kenyon, Olivia, Javed, Omar A., Sogaolu, Opeyemi O., Birmpili, Panagiota, Haylock-Vize, Patricia, Green, Patrick A., Carroll, Patrick J., Yang, Peiming, Beak, Philip, Persson, Pia, Tam, Pok Him Johnson, Waqar, Rabia, Morley, Rachael L., Bowden, Rachel Clare, Eyre, Rachel L., Pankhania, Rahul M., Sahemey, Rajpreet S., Kabariti, Rakan, Rawashdeh, M., Arab, Rawashdeh S., Rollett, Rebecca A., Nicholas, Rebecca S., Morgan, Rebecca V., Limb, Richard, Robinson, Richard Mark, Hayes, Richard S., Daureeawoo, Ridwan, Cooke, Robert A., Espey, Robert A.J., Chessman, Robert, Whitham, Robert D.J., Payne, Robert E., Staruch, Robert, Alho, Roberto J.R., Gordon, Robin, Cuthbert, Rory, Harrison, Roseanna B., Scott, Rupert A., Parks, Ruth M., Cheong, Ryan C.T., Hillier-Smith, Ryan L., Moffatt, Ryan, Rehman, Saad, Ambren, Sabah, Abdulal, Sabria, Kulkarni, Sagar, Hopwood, Sam, Greenfield, Samantha H., Mehta, Samir K., Haines, Samuel, AlSaati, Sarah A., Williams, Sarah A., El-Badawy, Sarah, Barlow, Sarah L., Pywell, Sarah, Pollock, Sarah-jayne, Lampridis, Savvas, Nazarian, Scarlet, Rezvani, Sean, Scattergood, Sean, Toescu, Sebastian M., Hotonu, Sesi, Shaikh, Shafaque, Rupani, Shamil, Hasan, Shumaila, Pradeep, Shwetha, Cole, Simon J., Growcott, Siona A., Bedoya, Sofia E., Ike, Sonia I., Bodnarescu, Stefan V., Seppings, Stella C., Poyntz, Stephanie A., Jordan, Stevan J., Iqbal, Sundas, Das, Suparna, Chatterjee-Woolman, Suravi, Shumon, Syed, Morrison, Tamsin E.M., Sibartie, Tara, Aboelmagd, Tariq, Russell, Thomas B., Seddon, Thomas C., Stringfellow, Thomas D., Goldsmith, Thomas, Banks, Thomas H.F., Tolley, Thomas, Oputa, Tobenna J., Kanzara, Todd T., Challoner, Tom, Urbonas, Tomas, Richards, Tomos B., Morrison-Jones, Victoria J., Garikapati, Vivek, Al-Azzani, Waheeb A.K., Zahra, Wajiha, Ho, Weiguang, Al-Dhahir, Wesam, Gibson, William G.W., Grant, Yasmin, Hijazi, Yasser, Chiang, Yayganeh, Gundkalli, Zobia K., Seymour, Zoe M., and Panayi, Zoe

Published
2018
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46. Comparison of Simulation-Based versus Cadaveric-Tissue-Based Ocular Trauma Training on Novice Ophthalmologists: Repair of Corneal Laceration Model

Author

Boonkit Purt, Timothy Ducey, Sean Sykes, Joseph F. Pasternak, Denise S. Ryan, Rose K. Sia, and Marcus H. Colyer

Subjects
ophthalmology, simulation, training, cornea, trauma, Ophthalmology, RE1-994
Abstract

Purpose The aim of this study was to evaluate whether the simulated tissue models may be used in place of animal-based model for corneal laceration repair for surgical skills acquisition. Design Prospective randomized controlled trial. Participants Seventy-nine military and civilian 2nd- and 3rd-year ophthalmology residents and 16 staff ophthalmologists participating in the Tri-Service Ocular Trauma Skills Laboratory at the Uniformed Services University (Bethesda, MD). Methods Resident ophthalmologists underwent preliminary evaluation of their ability to close a 5-mm linear, full-thickness corneal laceration involving the visual axis. They then were randomized to undergo 90 to 120 minutes of either simulator-based (SIM) or swine cadaveric-tissue-based (CADAVER) corneal laceration repair. The same evaluation was performed post training. On a more limited basis, the study was repeated for attending ophthalmologists to act as a pilot for future analysis and test efficacy for “refresher” training. Main Outcome Measures Successful wound closure with secondary outcomes of suture length, tension, depth, and orientation, as graded by attending ophthalmologists. Results No significant difference in CADAVER versus SIM groups in the primary outcome of watertight wound closure of the corneal laceration. CADAVER group performed better than SIM group for certain metrics (suture depth, p = 0.009; length, p = 0.003; and tension, p = 0.043) that are associated with poor wound closure and increased amount of induced corneal astigmatism. For attending ophthalmologists, six of the eight in each group (SIM and CADAVER) retained or improved their skills. Conclusions For resident ophthalmologists, SIM training is sufficient for achieving the primary outcome of watertight wound closure. However, CADAVER training is superior for wound metrics for the ideal closure. For attending ophthalmologists, SIM training may be useful for retention of skills.

Published
2021
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50. Management and early outcomes of children with appendicitis in the UK and Ireland during the COVID-19 pandemic: a survey of surgeons and observational study

Author

Nigel J Hall, David Williams, Vivek Gupta, Anna-may Long, Nuha Yassin, Alan Askari, David Colvin, Stewart Cleeve, Arun Kelay, Chris Driver, Clare Rees, Eleri Cusick, Hetal Patel, Ingo Jester, Khalid Elmalik, Sean Marven, Tim Bradnock, Oliver Brown, Andrew Jackson, Richard Egan, Laura Phillips, Marianne Hollyman, Bankole Oyewole, Fenella Welsh, Dale Vimalachandran, Melissa Gabriel, Kate Cross, Iain Yardley, Mark Peter, Andrew Beamish, Sophie Lewis, Milan Gopal, Joshua McIntyre, Merrill McHoney, Ionica Stoica, Hany Gabra, Tristan Boam, Angeliki Kosti, Katie cross, Andrew Mitchell, Michael Terry, George S Bethell, Clare M Rees, Jonathan R Sutcliffe, Florin Djendov, Victor Emordi, Sarah Staight, Christina Major, Oscar Croysdale, Mike Nelson, Hannah Rhodes, Juliette King, Gillian Winter, Selena Curkovic, Raef Jackson, Bhushanrao Jadhav, Thomas Raymond, Vijay Gangalam, Deepak Selvakumar, Reda Habak, Muslim Abdullah, Mohamed Ahmed Osama, Khlud Asanai, Noman Zafar, Sophia Lewis, Florence Kashora, Dixa Thakrar, Dean Rex, Annita Budzanowski, Jennifer Binnington, Simon Timbrell, Megan Ridgeway, Shirley Chan, Amani Asour, Adetayo Aderombi, Donald Menzies, Ali Murtada, Corina Dragu, Vincent Quan, Krashna Patel, Sesi Hotonu, Ashley Meikle, Ajay Belgaumkar, Prabhat Narayan, Thomas Badenoch, Frances Goulder, Katie Siggens, Kizzie Peters, Fiona Kirkham, Paul Froggatt, Karen Lai, Cristina Navarro, Dorinda Chandrabose, Simon Toh, Elizabeth Gemmill, Keira Lily, Mark Dilworth, Dimitrios Stamatiou, Alasdair Macmillan, Danielle Clyde, Majid Rashid, Gandrapu Srinivas, Katherine Buckley, Darren Smith, Henry Dowson, Gautam Singh, Seshu Kumar Bylapudi, Louise Phillips, Kimberley Hallam, Marisa Clemente, Karol Pal, George Ninkovic-Hall, Emila Paul, Theo Pelly, Joe Vance-Daniel, Venkatesh Kanakala, Edward J Nevins, James Dixon, Michael John, Jude Prince, Georgios Karagiannidis, Suzette Samlalsingh, Chrsitine Ozone, Amina Bouhelal, Siddhartha Handa, Sathasivam Rajeev, Ellen Ross, Ali Wadah, John Hallett, Shirish Tewari, Vinay Shah, Nick Reay-Jones, Salman Bodla, Harriet Corbett, Sumita Chhabra, Athanasios Tyraskis, Benjamin Allin, Angus Fitchie, Michael Stanton, Mark Vipond, Harry Dean, Matthew Boal, Jonathan Goring, Mahmoud Marei, Christian Verhoef, Jonathan Ducey, Chipo Mushonga, Dan Frith, Ashok Ram, Ferzine Mohamed, Rick MacMahon, Mohammed Fakhrul-Aldeen, Iain Bain, Graham Branagan, Rachel Carten, Chee Wan Lai, Anindya Niyogi, Claudia Koh, Christian Fox, Stavros Loukogeorgakis, Joe Curry, Jayaram Sivaraj, Milda Jancauskaite, Helen Please, Wayne Fradley, Maki Jitsumara, Sinead Hassett, Ancuta Muntean, Sarah Yassin, Suzanne Lawther, Ciaran Durand, Mohamed Eltom, Kirsty Brennan, Clara Chong, Hasan Mukhtar, Hany Khalil, Stephanie Clark, Ashish Desai, Amulya Saxena, Joshua Cave, Alistair Sharples, Lukas O’Brien, George Kerans, Ashwini Ghorpade, Felicity Arthur, Muhammad Tobbal, Rachael Robertson, Ben Martin, Ben Woodward, Kieran McGovern, and Duncan Rutherford

Subjects
Pediatrics, RJ1-570
Abstract

Objectives Acute appendicitis is the most common surgical condition in children. In the UK, appendicectomy is the most common treatment with non-operative management unusual. Due to concerns about the risk of SARS-CoV-2 transmission during surgical procedures, surgeons were advised to consider non-operative treatment and avoid laparoscopy where possible. This study aims to report management and outcomes, to date, of children with appendicitis in the UK and Ireland during the COVID-19 pandemic.Design Survey of consultant surgeons who treat children with appendicitis that informed a prospective multicentre observational cohort study.Setting Data were collected from centres in the UK and Ireland for cases admitted between 1 April and 31 May 2020 (first 2 months of the COVID-19 pandemic) at both general surgical and specialist paediatric surgical centres.Participants The study cohort includes 838 children with a clinical and/or radiological diagnosis of acute appendicitis of which 527 (63%) were male.Main outcomes measured Primary outcome was treatment strategy used for acute appendicitis. Other outcomes reported include change in treatment strategy over time, use of diagnostic imaging and important patient outcomes to 30 days following hospital admission.Results From very early in the pandemic surgeons experienced a change in their management of children with appendicitis and almost all surgeons who responded to the survey anticipated further changes during the pandemic. Overall, 326/838 (39%) were initially treated non-operatively of whom 81/326 (25%) proceeded to appendicectomy within the initial hospital admission. Of cases treated initially surgically 243/512 (48%) were performed laparoscopically. Diagnostic imaging was used in 445/838 (53%) children. Cases treated non-operatively had a shorter hospital stay than those treated surgically but hospital readmissions within 30 days were similar between groups. In cases treated surgically the negative appendicectomy rate was 4.5%. There was a trend towards increased use of surgical treatment and from open to laparoscopic appendicectomy as the pandemic progressed.Conclusion Non-operative treatment of appendicitis has been widely used for the first time in children in the UK and Ireland and is safe and effective in selected patients. Overall patient outcomes do not appear to have been adversely impacted by change in management during the pandemic thus far.

Published
2020
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