18 results on '"Discepoli, N."'
Search Results
2. Bond strength to radicular dentin of two experimental luting cements
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Bonarini G, Ferrari Cagidiaco E, and Discepoli N
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Bond strength ,Resin cements ,polymerization techniques ,Post ,Radicular dentin ,Dentistry ,RK1-715 - Abstract
Aim The aim of this study was to test two different of experimental cements based on two types of polymerization techniques comparing them with one already well known in the market. Materials and methods Thirty intact central incisors, extracted for periodontal reasons, were selected and endodontically treated, then were randomly divided into 3 groups of 10 samples: Group 1, light cured composite experimental material with self-etch adhesive and dual polymerization activator; Group 2, dual experimental core build-up with self-etch adhesive and dual-polymer activator; Group 3 (control group), dual cement with self-etch adhesive and dual polymerization activator. One fiber post was luted into the root canal strictly following manufacturer’s instructions. Each sample was cut in slices in order to perform the push-out bond strength test with a testing machine. To express the bond strength in MegaPascals (MPa), the breaking load recorded in Newton (N) was divided by the area of the bonded interface (A) in mm2. The area of the bond interface was calculated as the area of the surface of a truncated cone using the formula: A = π (R + r) [h2 + (Rr) 2] 1/2, where R represents the major radius of the coronal post, r represents the minor radius of the apical post and h is the thickness of the slice in millimeters. The diameters and thickness of the slice were measured individually using a digital caliper with 0.01 mm precision. After the test, each slide was observed to detect the type of failure and classified as adhesive between cement and dentin (AD); adhesive between the cement and the post (AP); fracture of the sample, cohesive inside the post and dentin (FR); cohesive in cement (CC); mixed (M). Results Group 2 recorded the highest values of adhesion strength, group 1 the lowest. There were no statistically significant differences among groups 1 and 2 and controls. The most common failure mode was the mixed one and the less frequent was the adhesive type between the post and the cement. Conclusions Within the limitations of this study, it can be concluded that the bond strength of experimental resin cements is comparable to that of a cement marketed by the same manufacturer, used here as a control and well known in the market.
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- 2019
- Full Text
- View/download PDF
3. Periodontal Diagnosis: Shall Saliva and Gingival Crevicular Fluid Help the Clinician?
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Raffaele Mirra, Discepoli N, and Crystal Marruganti
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Periodontitis ,Crevicular fluid ,Periodontal tissue ,Saliva ,business.industry ,medicine ,Dentistry ,Gingival inflammation ,medicine.symptom ,business ,medicine.disease ,Gingival recession - Published
- 2020
4. Post-Retained Single Crowns versus Fixed Dental Prostheses: A 7-Year Prospective Clinical Study
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Ferrari, Marco, Ferrari, Marco, Sorrentino, Roberto, Juloski, Jelena, Grandini, Simone, Carrabba, Michele, Discepoli, N., Ferrari Cagidiaco, E., Ferrari, Marco, Ferrari, Marco, Sorrentino, Roberto, Juloski, Jelena, Grandini, Simone, Carrabba, Michele, Discepoli, N., and Ferrari Cagidiaco, E.
- Abstract
Biomechanical integrity of endodontically treated teeth (ETT) is often compromised. Degree of hard tissue loss and type of final prosthetic restoration should be carefully considered when making a treatment plan. The objective of this prospective clinical trial was to assess the influence of the type of prosthetic restoration as well as the degree of hard tissue loss on 7-y clinical performance of ETT restored with fiber posts. Two groups (n = 60) were defined depending on the type of prosthetic restoration needed: 1) single unit porcelain-fused-to-metal (PFM) crowns (SCs) and 2) 3- to 4-unit PFM fixed dental prostheses (FDPs), with 1 healthy and 1 endodontically treated and fiber post-restored abutment. Within each group, samples were divided into 2 subgroups (n = 30) according to the amount of residual coronal tissues after abutment buildup and final preparation: A) >50% of coronal residual structure or B) equal to or lt 50% of coronal residual structure. The clinical outcome was assessed based on clinical and intraoral radiographic examinations at the recalls after 6, 12, 24, 36, 48, and 84 mo. Data were analyzed by Kaplan-Meier log-rank test and Cox regression analysis (P lt 0.05). The overall 7-y survival rate of ETT restored with fiber post and either SCs or FDPs was 69.2%. The highest 84-mo survival rate was recorded in group 1A (90%), whereas teeth in group 2B exhibited the lowest performance (56.7% survival rate). The log-rank test detected statistically significant differences in survival rates among the groups (P = 0.048). Cox regression analysis revealed that the amount of residual coronal structure (P = 0.041; hazard ratio [HR], 2.026; 95% confidence interval [CI] for HR, 1.031-3.982) and the interaction between the type of prosthetic restoration and the amount of residual coronal structure (P = 0.024; HR, 1.372; 95% CI for HR, 1.042-1.806) were statistically significant factors for survival.
- Published
- 2017
5. Early healing of the alveolar process after tooth extraction: an experimental study in the beagle dog
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Discepoli N, Vignoletti F, Laino L, Muñoz F, Sanz M., DE SANCTIS , MASSIMO, Discepoli, N, Vignoletti, F, Laino, L, DE SANCTIS, Massimo, Muñoz, F, and Sanz, M.
- Published
- 2013
6. Bone modelling at fresh extraction sockets: immediate implant placement versus spontaneous healing: an experimental study in the beagle dog
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Vignoletti F, Discepoli N, Müller A, Muñoz F, Sanz M., DE SANCTIS , MASSIMO, Vignoletti, F, Discepoli, N, Müller, A, DE SANCTIS, Massimo, Muñoz, F, and Sanz, M.
- Published
- 2012
7. Immediate implants at fresh extraction sockets: an experimental study in the beagle dog comparing four different implant systems. Soft tissue findings
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DE SANCTIS , MASSIMO, Vignoletti F, Discepoli N, Muñoz F, Sanz M., DE SANCTIS, Massimo, Vignoletti, F, Discepoli, N, Muñoz, F, and Sanz, M.
- Published
- 2010
8. Efficacy of periodontal plastic procedures in the treatment of multiple gingival recessions
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Graziani, F. Gennai, S. Roldán, S. Discepoli, N. Buti, J. Madianos, P. Herrera, D.
- Abstract
Objective: To systematically review the efficacy of periodontal plastic procedures (PPP) in the treatment of multiple gingival recessions (MGR). Methods: Randomized clinical trials (RCT) on MGR treatment with at least 6 months duration were identified through electronic databases and handsearched journals. Primary outcomes were complete root coverage (CRC) and percentage of root coverage (PRC). Weighted means and forest plots were calculated for all PPP. Subgroup analysis was performed according to the type of flap. A Bayesian network meta-analysis (NM) on secondary outcomes was also performed. Results: Nine trials including 208 subjects and 858 recessions were identified. CRC after PPP was 24-89%. Mean weighted PRC was 86.27% (95% CI 80.71- 91.83; p < 0.01). Heterogeneity of the literature prevented inter-techniques comparison. Coronally advanced flap (CAF) shows the higher variability in terms of CRC. Modified CAF and tunnel approaches show higher level of CRC. The NM suggests that CAF plus graft showed the higher probability of being the best treatment. Conclusions: Limited evidence is available for MGR coverage. PPP are associated with high level of efficacy, in terms of PRC, and high variability of CRC. Indirect evidence indicates that CAF may benefit from newer variations of the technique and by the additional use of grafting. © 2014 John Wiley & Sons A/S.
- Published
- 2014
9. Regeneración de los defectos periodontales intraóseos: combinación de membranas barrera y material de relleno: evidencia preclínica y clínica
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Discepoli, N., Costa Berenguer, X., and Bascones-Martínez, A.
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barrier membranes ,histology ,grafting materials ,terapia periodontal regenerativa ,Modelos animales ,barreras ,histología ,regenerative periodontal therapy ,modelos preclínicos ,preclinical models ,material de relleno ,Animal models - Abstract
La terapia periodontal regenerativa tiene como objetivo lo de restaurar los tejidos de soporte periodontal y debería resultar en la formación de nueva inserción conectiva y (nuevo cemento con nuevas fibras del ligamento periodontal insertada) y nuevo hueso. Evidencia histológica en modelos preclínicos ha demostrado regeneración después de tratamiento con membranas barreras, distintos tipos de material de relleno y una combinación de los dos. De todas formas, todavía no queda claro en qué extensión la combinación de membranas barreras y material de relleno puede promover de manera adicional el proceso de regeneración en comparación con tratamientos únicos. Regenerative periodontal therapy aims to predictably restore the tooth's supporting periodontal tissues and should result in formation of a new connective tissue attachment (i.e. new cementum with inserting periodontal ligament fibres) and new alveolar bone. Histologic evidence from preclinical models has demonstrated periodontal regeneration following treatment with barrier membranes, various types of grafting materials or a combination thereof. However, it is still not clear to what extenta combination of barrier membranes and grafting materials may additionally enhance the regeneration process compared with barrier membranes alone, grafting materials alone or open flap debridement.
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- 2012
10. Enfermedad de la mucosa oral: Penfigoide de las membranas mucosas
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Discepoli, N. and Bascones Martínez, A.
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corticosteroides ,oral ,skin ,mucosas orales ,immunosuppressants ,Penfigoide ,autoimmune ,autoinmunidad ,inmunosupresores ,Pemphigoid ,corticosteroids - Abstract
Los trastornos vesículobullosos subepiteliales representan desordenes autoinmunitarios que cogen origen de reacciones dirigidas hacia componentes de los hemidesmosomas o bien de las Zonas de la Membrana Basal (ZMB) de los epitelios escamosos estratificados. A estos trastornos ha sido conferidoel término de enfermedades ampollosa subepiteliales inmunomediadas (EASIM) y el penfigoide de las membranas mucosas (PMM) es el más frecuente. Todas las enfermedades subepiteliales vesiculobullosas se presentan como lesiones ampollosas y descamativas, y el diagnostico debe de ser confirmado por una biopsia junta a tinción inmunológica. No hay un único tratamiento capaz de controlar todas las enfermedades subepiteliales vesiculoampollosas; las diferencias inmunológicas entre las EASIM proporciona diferencias en las respuestas al tratamiento. Hoy en día el tratamiento inmunorregulador es usado para controlar la lesión oral de PMM. Subepithelial vesiculobullous conditions are chronic autoimmune disorders that arise from reactions directed against components of the hemidesmosomes or basement membrane zones (BMZ) of stratified squamous epithelium to which the term immune-mediated subepithelial blistering diseases (IMSEBD) has been given. Mucous membrane pemphigoid (MMP) is the most common, but variants do exist. All subepithelial vesiculobullous disorders present as blisters and erosions, and diagnosis must be confirmed by biopsy examination with immunostaining, sometimes supplemented by other investigations. No single treatment reliably controls all subepithelial vesiculobullous disorders; the immunological differences within IMSEBD may account for differences in responses to treatment. Currently, as well as improving oral hygiene, immunomodulatory treatment is used to control the oral lesions of MMP, but it is not known if its specific subsets reliably respond to different agents.
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- 2009
11. Controversias etiológicas, diagnósticas y terapéuticas de la periodontitis agresiva
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Discepoli, N and Bascones Martínez, A.
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Aggressive Periodontitis ,Modalidades de tratamiento ,Treatment modalities ,Diagnostico diferencial ,Diferencial Diagnosis ,Clasificación ,Patogenia ,Classification ,Periodontitis agresiva ,Etiopathogenia - Abstract
Se revisa la bibliografía más reciente al resguardo de la Periodontitis Agresiva, con particular atención a la etiología multifactorial, al diagnóstico, clínico y de laboratorio, y a la fase terapéutica. Se revisan también las controversias entre las diferentes clasificaciones que se propusieron hasta hoy. In this paper is reviewed the most recent bibliography about Aggressive Periodontitis, with particular attention on its multifactor aetiology, on diagnostic, clinic and laboratory, and on the therapeutic phase. The paper will review too the controversies among classifications proposed up to the date.
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- 2008
12. Actualización en radiología dental: Radiología convencional Vs digital
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Barbieri Petrelli, G, Flores Guillén, J, Escribano Bermejo, M, and Discepoli, N
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indirect digital radiography ,Radiología digital directa ,resolución ,radiología digital indirecta ,resolution ,Direct digital radiography - Abstract
Desde su incorporación a la práctica odontológica la radiología digital ha experimentado un importante desarrollo. El continuo avance de las tecnologías en las que se sustenta ha dotado a estos sistemas de interesantes prestaciones que pueden facilitar el diagnóstico y manejo de imágenes radiográficas. Con estos avances la radiología digital ha despertado un interés creciente entre los profesionales de la odontología, especialmente durante los últimos años, en los que ha aumentado notoriamente tanto la cantidad de sistemas comercializados como el número de odontólogos que han decidido sustituir la radiología convencional por un sistema digital en sus clínicas. En esta revisión de la literatura se tratará de ofrecer una visión actualizada de los distintos sistemas disponibles en la actualidad, así como una comparativa entre ellos basada en estudios publicados recientemente. Since its appearance in dentistry, digital radiology has experienced a notorious development. A constant advance in the corresponding technologies has enhanced these digital systems with interesting features which may facilitate radiological diagnosis and image management. Due to these advances digital radiology has elicited a growing interest in dentistry. Specially during the last years there has been an increase both in the amount of available systems and in the number of dentists who have incorporated a digital system in their offices. This literature review aims to offer an updated view of the available systems and a comparison of them based in recent studies.
- Published
- 2006
13. Immediate implants at fresh extraction sockets: bone healing in four different implant systems
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Fabio Vignoletti, Giovanni Zucchelli, Mariano Sanz, Massimo de Sanctis, Nicola Discepoli, de Sanctis M, Vignoletti F, Discepoli N, Zucchelli G, Sanz M., DE SANCTIS, Massimo, Vignoletti, F, Discepoli, N, Zucchelli, G, and Sanz, M.
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Dentistry ,Mandible ,Bone healing ,Osseointegration ,Bone resorption ,Bone remodeling ,Random Allocation ,Dogs ,Osteogenesis ,Alveolar Process ,medicine ,Animals ,Bicuspid ,Single-Blind Method ,Bone Resorption ,Tooth Socket ,Dental alveolus ,implant system ,Dental Implants ,Wound Healing ,business.industry ,Alveolar process ,Dental Implantation, Endosseous ,Buccal administration ,medicine.anatomical_structure ,Dental Prosthesis Design ,Tooth Extraction ,Periodontics ,Bone Remodeling ,Implant ,business ,fresh extraction sockets - Abstract
Objectives: To describe the differences in bone healing, when placing four different implant systems in fresh extraction sockets. Material and Methods: Eight beagle dogs received implants randomly installed into the distal socket of three P3 and four P4. Four-implant systems were evaluated. Each animal provided four test implant sites. All animals were sacrificed at 6 weeks after implant placement, providing specimens for histo-morphometric analysis of bone to implant contact (BIC), bone area, new bone formation, as well as histometric measurements of the ridge alterations. Results: No statistically significant difference was observed among the four-implant systems. The mean BIC % ranged between 58.5% and 72.1%. Bone modelling of the buccal plate was marked and amounted approximately to 2.5 mm, independently of the system used. Conclusion: This study failed to demonstrate differences in the healing pattern after 6 weeks when placing four different implant systems in fresh extraction sockets. In spite of achieving predictable osteointegration with the four implants studied, the occurrence of buccal bone resorption may limit the use of this surgical approach.
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- 2009
14. Fresh extraction socket: spontaneous healing vs. immediate implant placement
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Luigi Laino, Mariano Sanz, Nicola Discepoli, Massimo de Sanctis, Fernando Muñoz, Fabio Vignoletti, Discepoli, Nicola, Vignoletti, Fabio, Laino, Luigi, De Sanctis, Massimo, Muã±oz, Fernando, Sanz, Mariano, Discepoli, N, Vignoletti, F, Laino, L, DE SANCTIS, Massimo, Muñoz, F, and Sanz, M.
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Animal Experimentation ,Animal experiments ,medicine.medical_treatment ,Dentistry ,Wound healing ,Beagle ,Bone remodeling ,Dogs ,stomatognathic system ,medicine ,Dog ,Animals ,Animal experiment ,Tooth Socket ,Dental Implant ,Reduction (orthopedic surgery) ,Dental Implants ,business.industry ,Animal ,Dental Implantation, Endosseous ,Buccal administration ,Immediate implant ,Dental Implantation, Endosseou ,Bone implant interactions ,Resorption ,Dental Implantation ,Coronal plane ,Bone implant interaction ,Crest ,Oral Surgery ,business ,Endosseous - Abstract
Aim: To evaluate the impact that immediate implant placement may have on bone remodelling in comparison with adjacent sockets left to heal spontaneously. Materials and methods: In a beagle dog model (N = 16 dogs), mandibular premolars were extracted, and implants were placed in each distal socket (test) with the corresponding mesial site left to heal undisturbed (control). Healing was assessed measuring both the vertical distance between buccal and lingual crest (B'L') and the width of buccal and lingual walls at different levels. Five healing periods were evaluated. Differences between means for each variable and for each healing period between test and control were compared (Kruskal-Wallis test; Friedman test). Results: At 2 and 8 weeks of healing, the B'L' distance revealed significant higher values at test compared to control sites, being this difference three times higher at the end of the study (P < 0.05). In the test group, the width of the crest was reduced between baseline (0.37 [0.04]) and 8 weeks healing (0.13 [0.64]), demonstrating a 62% reduction of the initial width. These differences were not observed in the control group. Conclusions: Immediate implant placement into fresh extraction sockets may jeopardize the vertical bone remodelling of the socket. Furthermore, a tendency towards greater buccal horizontal resorption was observed in the most coronal aspect of the buccal bone crest.
- Published
- 2014
15. Analysis of The Reproducibility of Subgingival Vertical Margins Using Intraoral Optical Scanning (IOS): A Randomized Controlled Pilot Trial.
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Ferrari Cagidiaco E, Zarone F, Discepoli N, Joda T, and Ferrari M
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Background: The aim of this randomized controlled trial was to evaluate the capability of an IOS (Intra Oral Scanner) device, used in standardized conditions, to detect margins of abutments prepared with knife-edge finishing line located at three different levels in relation to the gingival sulcus., Methods: sixty abutment teeth for treatment with full crowns were selected and randomly divided in three groups accordingly to the depth of the finishing line: Group A: supragingival margin; Group B: 0.5-1.0 mm into the sulcus; Group C: 1.5-2.0 mm into the sulcus. Temporary crowns were placed for two weeks and then digital impressions (Aadva IOS 100, GC, Japan) were made of each abutment. As controls, analog impressions were taken, poured, and scanned using a laboratory scanner (Aadva lab scanner, GC, Japan). Two standard tessellation language (STL) files were generated for each abutment, subsequently processed, and superimposed by Exocad software (Exocad GmbH, Darmstadt, Germany), applying the "best-fit" algorithm in order to align the scan of the conventional with the digital impressions. The distances between each preparation margin and the adjacent gingival tissue were measured. Four measures were taken, two interproximally and buccally, for a total of six measures of each abutment considering three modes of impressions. The data were statistically evaluated using two-way analysis of variance (ANOVA) for each site and the Bonferroni test., Results: there was no difference between the two kinds of impression in Group A in both sites, in Group B a difference of 0.483 mm and 0.682 mm at interproximal and buccal sites, respectively, and in Group C 0.750 mm and 0.964 mm at interproximal and buccal sites, respectively. The analysis performed on a site level (mesial/distal/vestibular) for the depth of both vertical preparations revealed significant differences ( p < 0.0001). After a post hoc analysis (Bonferroni), vestibular sites of the shallow vertical preparations resulted in significantly lower values compared to the other sites prepared deeply., Conclusions: the results showed that the location of the margin is an important factor in making a precise and complete impression when IOS (Intra Oral Scanner) is used. Moreover, deep preparation into the sulcus is not recommended for IOS (Intra Oral Scanner) impressions.
- Published
- 2021
- Full Text
- View/download PDF
16. Clinical Outcomes of Endodontic Treatments and Restorations with and without Posts Up to 18 Years.
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Pontoriero DIK, Grandini S, Spagnuolo G, Discepoli N, Benedicenti S, Maccagnola V, Mosca A, Ferrari Cagidiaco E, and Ferrari M
- Abstract
Background: The aim of this study was to collect long-term restorative and endodontic outcomes of endodontically treated teeth (ETT)., Methods: 298 teeth were included in the study and were recalled up to 18 years with a media of 10.2 years. At baseline, 198 sample teeth (66.44%) showed symptoms and 164 (55%) had periapical radiolucency. The most frequently used obturation techniques were warm gutta-percha in 80% of cases, and by carrier in 20%. A total of 192 ETT were restored by direct resin composite restorations, and 106 posts were luted. Moreover, 75 (25.16%) direct restorations remained as final restorations, 137 single crowns (45.97%), 42 (14.09%) partial adhesive crowns, and 42 (14.09%) abutments of fixed bridges were the final treatments. Descriptive and inferential statistics were performed ( α = 0.05). A Cox regression model was made., Results: results showed success for 92.6% of ETT up to 18 years, 2.68% (8 ETT) showed irreversible failures, and 14 (4.69%) reversible complications. Four ETT (1.34%) failed because of root fracture and the other four (1.34%) because of endodontic complications. Eight ETT (2.69%) showed non-irreversible periodontal complications and the other six (2.01%) prosthodontic complications. Accordingly, with Kaplan-Meier analysis, the survival rate after 18 years was 97.3% (Interval of Confidence (IC) 95.1-98.3). The presence of a short or long (at least 1 mm related to radiographic apex) quality endodontic filling displayed a statistically significant higher risk of complication (hazard ratio (HR) = 17.00 (IC 5.68-56.84). Furthermore, a clinically detectable not precise coronal margins predicts the presence of any clinical complication with a hazard ratio almost seven times higher than endodontically treated teeth with a proper margin (HR = 6.89 (IC 2.03-23.38), while the presence of lucency at the baseline did not affect the risk of complication (HR = 0.575 (IC 0.205-1.61). The presence of post, tooth position in the arch, and the type of it did not show a high-risk rate (HR = 1.85, 1.98, and 2.24, respectively)., Conclusions: a correct filling (at the apex) of root canals combined with proper coronal margins allow obtaining a long-term high success rate in teeth with a periapical lesion at the baseline. The use of a post or not, when its placement is related to the residual amount of the crown, does not change the final outcome of the ETT.
- Published
- 2021
- Full Text
- View/download PDF
17. Oral Care and Quality Evaluation: A Multicentric Study on Periodontal Treatment.
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Graziani F, Minenna L, Karapets D, Herrera D, Nisi M, Gennai S, Gabriele M, Discepoli N, Petrini M, Marhl U, Perić M, Adriaen L, Alonso B, Bouchard P, Cardaropoli D, Cavalcanti R, Chackartchi T, Franch-Chillida F, Gianserra R, Guerrero A, Landi L, Masiero S, Mensi M, Moratti P, Oreglia F, Rupe A, Sanchez I, Sforza N, Capri D, Zabalegui I, Sanz M, Tonetti M, and Tomasi C
- Subjects
- Dental Care, Humans, Quality of Life, Surveys and Questionnaires, Oral Health, Periodontitis
- Abstract
Purpose: No information is available on the perception of the quality of care in patients treated for periodontitis. The purpose of this article was to assess how periodontitis-affected patients perceive the quality of periodontal treatment (PT) and to measure the factors which may influence it., Materials and Methods: 306 subjects who completed PT were invited to participate. Questionnaires and visual analogic scales (VAS) evaluating perception of quality of care, symptoms, and oral health related quality of life (OHRQoL) were handed out. Oral and periodontal indicators were collected before and after treatment. The impact of different factors on perception of quality was assessed with a regression model., Results: Quality evaluation was high yet unrelated for both patients and clinicians (p = 0.983). Quality was negatively influenced by the number of residual oral infections (p < 0.001), patient's age (p = 0.07) and presence of residual pain at completion of PT (p = 0.02). Professionalism, kindness of the staff and communication skills were the characteristics mostly appreciated. The OHRQoL was influenced by the number of residual teeth (p < 0.001), increasing age of patients (p = 0.08), number of residual infections (p < 0.01) and pain (p = 0.04)., Conclusions: Patients' quality perception appeared to be influenced by clinical and emotional aspects. Oral care providers should be aware of the impact of non-clinical factors in patients' appreciation of quality of treatment.
- Published
- 2020
- Full Text
- View/download PDF
18. Efficacy of Enamel Derivatives to Improve Keratinized Tissue as Adjunct to Coverage of Gingival Recessions: A Systematic Review and Meta-Analysis.
- Author
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Discepoli N, Mirra R, and Ferrari M
- Abstract
Background: The systematic review was designed to answer the following focused question: Are enamel matrix derivatives able to improve the quantity of keratinized tissue (KT) around natural dentition in patients with recessions defects after their treatment with periodontal plastic procedures?, Methods: Only Randomized Clinical Trials (RCT) in English language evaluating root coverage procedures in combination with enamel matrix derivatives (commercially known as Emdogain
® -EMD), with at least 10 subjects and a minimum duration of six months, were included. The search was applied to PUBMED and SCOPUS and it consists of a combination of MeSH terms and free text words (from January 2000 to June 2019). Risk of bias in individual studies and across studies was also evaluated., Results: After the full text analysis and the exclusion of further 18 articles, 12 articles were finally included. In total 639 recessions were treated (334 tests and 305 control). The recessions defects were classified according to the classification of Miller (Class I, II, III, IV). Only one trial included Miller Class III recessions (7 in total). Enamel matrix derivatives were applied in conjunction with Coronally Advanced Flap (CAF), Coronally Advanced Flap + Sub Epithelial Connective Tissue Graft (CAF + CTG), Semilunar Flap (SF). For the group CAF vs CAF + EMD the mean difference between the keratinized tissue gain in the two procedures was 0.40 mm (95% Confindence Interval Lower/Upper: 0.014-0.81) (p < 0.058); for the comparison CAF + CTG + EMD vs. CAF + CTG the mean difference between the two groups resulted in -0.06 mm (95% Confindence Interval Lower Upper -0.45 to 0.33) (p = 0.7603)., Discussion: Randomized clinical trials included medium-low quality evidence. The application of Enamel Matrix Derivatives to surgical procedures aimed to cover gingival recessions does not add robust clinical benefit to conventional plastic procedure alone.- Published
- 2019
- Full Text
- View/download PDF
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