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2. Chemoprofiling and medicinal potential of underutilized leaves of Cyperus scariosus

Author

Gandhi, Yashika, Kumar, Vijay, Singh, Gagandeep, Prasad, Shyam Baboo, Mishra, Sujeet K., Soni, Hemant, Rawat, Hemant, Singh, Simranjeet, Charde, Vaibhav, Gupta, Akhil, Dhanjal, Daljeet Singh, Jha, Sudhanshu Kumar, Tandon, Smriti, Bhagwat, Prateeksha, Arya, Jagdish C., Ramamurthy, Praveen C., Acharya, Rabinarayan, Narasimhaji, Ch. Venkata, Singh, Arjun, Singh, Ravindra, Srikanth, Narayanam, and Webster, Thomas J.

Published
2024
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19. Mycology-Nanotechnology Interface: Applications in Medicine and Cosmetology

Author

Dhanjal,Daljeet Singh, Mehra,Parul, Bhardwaj,Sonali, Singh,Reena, Sharma,Parvarish, Nepovimova,Eugenie, Chopra,Chirag, and Kuca,Kamil

Subjects
International Journal of Nanomedicine
Abstract

Daljeet Singh Dhanjal,1,* Parul Mehra,2,* Sonali Bhardwaj,1,* Reena Singh,1 Parvarish Sharma,3 Eugenie Nepovimova,4 Chirag Chopra,1 Kamil Kuca4,5 1School of Bioengineering and Biosciences, Lovely Professional University, Phagwara, Punjab, India; 2Central Research Institute, Kasauli, Himachal Pradesh, India; 3School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India; 4Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, 50003, Czech Republic; 5Biomedical Research Center, University Hospital Hradec Kralove, Hradec Kralove, 50005, Czech Republic*These authors contributed equally to this workCorrespondence: Kamil Kuca, Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, 50003, Czech Republic, Tel +420 603 289 166, Email kamil.kuca@uhk.cz Chirag Chopra, School of Bioengineering and Biosciences, Lovely Professional University, Jalandhar-Delhi GT Road, Phagwara, Punjab, 144411, India, +91-7837815676, Email chirag.18298@lpu.co.inAbstract: In today’s time, nanotechnology is being utilized to develop efficient products in the cosmetic and pharmaceutical industries. The application of nanotechnology in transforming bioactive material into nanoscale products substantially improves their biocompatibility and enhances their effectiveness, even when used in lower quantities. There is a significant global market potential for these nanoparticles because of which research teams around the world are interested in the advancements in nanotechnology. These recent advances have shown that fungi can synthesize metallic nanoparticles via extra- and intracellular mechanisms. Moreover, the chemical and physical properties of novel metallic nanoparticles synthesised by fungi are improved by regulating the surface chemistry, size, and surface morphology of the nanoparticles. Compared to chemical synthesis, the green synthesis of nanoparticles offers a safe and sustainable approach for developing nanoparticles. Biosynthesised nanoparticles can potentially enhance the bioactivities of different cellular fractions, such as plant extracts, fungal extracts, and metabolites. The nanoparticles synthesised by fungi offer a wide range of applications. Recently, the biosynthesis of nanoparticles using fungi has become popular, and various ways are being explored to maximize nanoparticles synthesis. This manuscript reviews the characteristics and applications of the nanoparticles synthesised using the different taxa of fungi. The key focus is given to the applications of these nanoparticles in medicine and cosmetology.Keywords: fungi, biological application, biosynthesis, nanoparticles, nanotechnology

Published
2022

20. Phyto-Enrichment of Yogurt to Control Hypercholesterolemia: A Functional Approach

Author

Kumar, Harsh, primary, Bhardwaj, Kanchan, additional, Cruz-Martins, Natália, additional, Sharma, Ruchi, additional, Siddiqui, Shahida Anusha, additional, Dhanjal, Daljeet Singh, additional, Singh, Reena, additional, Chopra, Chirag, additional, Dantas, Adriana, additional, Verma, Rachna, additional, Dosoky, Noura S., additional, and Kumar, Dinesh, additional

Published
2022
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22. Concepts of advanced therapeutic delivery systems for the management of remodeling and inflammation in airway diseases

Author

Dhanjal, Daljeet Singh, primary, Sharma, Parvarish, additional, Mehta, Meenu, additional, Tambuwala, Murtaza M, additional, Prasher, Parteek, additional, Paudel, Keshav R, additional, Liu, Gang, additional, Shukla, Shakti D, additional, Hansbro, Philip M, additional, Chellappan, Dinesh Kumar, additional, Dua, Kamal, additional, and Satija, Saurabh, additional

Published
2022
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23. Biological Biosensors for Monitoring and Diagnosis

Author

Singh, Simranjeet, Kumar, Vijay, Dhanjal, Daljeet Singh, Datta, Shivika, Prasad, Ram, and Singh, Joginder

Subjects
Disease diagnosis, Biosensors, environment monitoring, Drug delivery, Article
Abstract

Quantification and detection of various contaminants in the ecosystem have become critically important in the past few decades due to their exhaustive use in soil and aquatic ecosystems. The contamination by both organic and inorganic contaminants in the ecosystem has drawn attention due to their persistence, biological accumulation, and toxicity. Organic contaminants reach the air, water, food, soil, and other systems through drift mechanism and have detrimental effect on various life systems after entering the food chain, thus interfering the normal biological process of the ecosystem. Inorganic contaminants have less solubility, primarily get adsorbed, and accumulate on lower sediments. The sources of both organic and inorganic contaminants include anthropogenic activities which dispose industrial and sewage effluent directly into water bodies. Most of the contaminants are very much toxic and have tumorigenic, carcinogenic, and mutagenic effect on various life-forms. Biosensors have various prospective and existing applications in the detection of these compounds in the environment by transducing a signal. It also has immense applications in the detection of different contaminants in the food industry, environmental monitoring, disease diagnosis, etc. where reliable and precise analyses are required. This chapter points out a comprehensive glimpse on different biosensors and their characteristics, operating principles, and their designs, based on transduction types and biological components. Efforts have been made to summarize various applications of biosensors in food industry, environmental monitoring, drug delivery systems, and clinical diagnostics etc.

Published
2020

24. Metagenomics Analyses: A Qualitative Assessment Tool for Applications in Forensic Sciences

Author

Dileep, Devika, Ramesh, Aadya, Sojan, Aarshaa, Dhanjal, Daljeet Singh, Kaur, Harinder, and Kaur, Amandeep

Subjects
Microbial forensics, Human microbiota, Molecular markers, Metagenomics, DNA profiling, Article
Abstract

Forensic science deals with the scientific investigation of evidence collected from crime scenes. Since decades, forensic scientists have solved complex and sophisticated crimes using biological evidence. The forensic analyses include the biochemical profiling, physicochemical profiling and molecular analysis of the evidence. The biochemical profiling involves the analysis of the lipid-profile, the presence of toxins in the visceral fluids and enzyme activity analyses. However, it has come to light that detailed molecular evidence, besides the conventional DNA-evidence, is required for the accurate implication of an individual in a crime. Pre-meditated crimes with cadavers found in outbound locations are especially challenging. Many times, the biological samples do not provide enough DNA to carry out the molecular analysis. Metagenomics has paved a way to explore the microbiome of the biological evidence from which the DNA-evidence cannot be extracted. Using high-throughput sequencing methods followed by sequence analysis, the environmental samples of evidence can give valuable insights into the detailed molecular patterns. These patterns can make the identification or comparison of subjects easier. The chapter discusses the genomic analysis, proteome analysis and the metagenomic approaches for investigating a crime scene.

Published
2020

25. Wonder or evil?: Multifaceted health hazards and health benefits of Cannabis sativa and its phytochemicals

Author

Datta, Shivika, primary, Ramamurthy, Praveen C., additional, Anand, Uttpal, additional, Singh, Simranjeet, additional, Singh, Amritpal, additional, Dhanjal, Daljeet Singh, additional, Dhaka, Vaishali, additional, Kumar, Sanjay, additional, Kapoor, Dhriti, additional, Nandy, Samapika, additional, Kumar, Manoj, additional, Koshy, Eapen P., additional, Dey, Abhijit, additional, Proćków, Jarosław, additional, and Singh, Joginder, additional

Published
2021
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26. Nanotechnology based advanced therapeutic strategies for targeting interleukins in chronic respiratory diseases

Author

Hussain, Md Sadique, primary, Sharma, Parvarish, additional, Dhanjal, Daljeet Singh, additional, Khurana, Navneet, additional, Vyas, Manish, additional, Sharma, Neha, additional, Mehta, Meenu, additional, Tambuwala, Murtaza M., additional, Satija, Saurabh, additional, Sohal, Sukhwinder Singh, additional, Oliver, Brian.G.G., additional, and Sharma, Hari S., additional

Published
2021
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28. Applications of Fruit Polyphenols and Their Functionalized Nanoparticles Against Foodborne Bacteria: A Mini Review

Author

Kumar, Harsh, primary, Bhardwaj, Kanchan, additional, Cruz-Martins, Natália, additional, Nepovimova, Eugenie, additional, Oleksak, Patrik, additional, Dhanjal, Daljeet Singh, additional, Bhardwaj, Sonali, additional, Singh, Reena, additional, Chopra, Chirag, additional, Verma, Rachna, additional, Chauhan, Prem Parkash, additional, Kumar, Dinesh, additional, and Kuča, Kamil, additional

Published
2021
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29. Potential Usage of Edible Mushrooms and Their Residues to Retrieve Valuable Supplies for Industrial Applications

Author

Kumar, Harsh, primary, Bhardwaj, Kanchan, additional, Sharma, Ruchi, additional, Nepovimova, Eugenie, additional, Cruz-Martins, Natália, additional, Dhanjal, Daljeet Singh, additional, Singh, Reena, additional, Chopra, Chirag, additional, Verma, Rachna, additional, Abd-Elsalam, Kamel A., additional, Tapwal, Ashwani, additional, Musilek, Kamil, additional, Kumar, Dinesh, additional, and Kuča, Kamil, additional

Published
2021
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30. Conifers Phytochemicals: A Valuable Forest with Therapeutic Potential

Author

Bhardwaj, Kanchan, primary, Silva, Ana Sanches, additional, Atanassova, Maria, additional, Sharma, Rohit, additional, Nepovimova, Eugenie, additional, Musilek, Kamil, additional, Sharma, Ruchi, additional, Alghuthaymi, Mousa A., additional, Dhanjal, Daljeet Singh, additional, Nicoletti, Marcello, additional, Sharma, Bechan, additional, Upadhyay, Navneet Kumar, additional, Cruz-Martins, Natália, additional, Bhardwaj, Prerna, additional, and Kuča, Kamil, additional

Published
2021
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31. Detection of bacterial pathogens and antibiotic residues in chicken meat: a review

Author

Kumar, Harsh, Bhardwaj, Kanchan, Kaur, Talwinder, Nepovimova, Eugenie, Kuča, Kamil, Kumar, Vinod, Bhatia, Shashi Kant, Dhanjal, Daljeet Singh, Chopra, Chirag, Singh, Reena, Guleria, Shivani, Bhalla, Tek Chand, Verma, Rachna, and Kumar, Dinesh

Subjects
multidrug‐resistant bacteria, chromatography‐based method, immunology‐based method, chicken, molecular‐based methods, biosensors, antibiotics
Abstract

Detection of pathogenic microbes as well as antibiotic residues in food animals, especially in chicken, has become a matter of food security worldwide. The association of various pathogenic bacteria in different diseases and selective pressure induced by accumulated antibiotic residue to develop antibiotic resistance is also emerging as the threat to human health. These challenges have made the containment of pathogenic bacteria and early detection of antibiotic residue highly crucial for robust and precise detection. However, the traditional culture-based approaches are well-comprehended for identifying microbes. Nevertheless, because they are inadequate, time-consuming and laborious, these conventional methods are not predominantly used. Therefore, it has become essential to explore alternatives for the easy and robust detection of pathogenic microbes and antibiotic residue in the food source. Presently, different monitoring, as well as detection techniques like PCR-based, assay (nucleic acid)-based, enzyme-linked immunosorbent assays (ELISA)-based, aptamer-based, biosensor-based, matrix-assisted laser desorption/ionization-time of flight mass spectrometry-based and electronic nose-based methods, have been developed for detecting the presence of bacterial contaminants and antibiotic residues. The current review intends to summarize the different techniques and underline the potential of every method used for the detection of bacterial pathogens and antibiotic residue in chicken meat.

Published
2020

32. Plant Prebiotics and Their Role in the Amelioration of Diseases

Author

Kaur, Amrit Pal, primary, Bhardwaj, Sonali, additional, Dhanjal, Daljeet Singh, additional, Nepovimova, Eugenie, additional, Cruz-Martins, Natália, additional, Kuča, Kamil, additional, Chopra, Chirag, additional, Singh, Reena, additional, Kumar, Harsh, additional, Șen, Fatih, additional, Kumar, Vinod, additional, Verma, Rachna, additional, and Kumar, Dinesh, additional

Published
2021
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33. Conifer-Derived Metallic Nanoparticles: Green Synthesis and Biological Applications

Author

Bhardwaj, Kanchan, primary, Dhanjal, Daljeet Singh, additional, Sharma, Anirudh, additional, Nepovimova, Eugenie, additional, Kalia, Anu, additional, Thakur, Shabnam, additional, Bhardwaj, Sonali, additional, Chopra, Chirag, additional, Singh, Reena, additional, Verma, Rachna, additional, Kumar, Dinesh, additional, Bhardwaj, Prerna, additional, and Kuča, Kamil, additional

Published
2020
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34. Fruit Extract Mediated Green Synthesis of Metallic Nanoparticles: A New Avenue in Pomology Applications

Author

Kumar, Harsh, primary, Bhardwaj, Kanchan, additional, Dhanjal, Daljeet Singh, additional, Nepovimova, Eugenie, additional, Șen, Fatih, additional, Regassa, Hailemeleak, additional, Singh, Reena, additional, Verma, Rachna, additional, Kumar, Vinod, additional, Kumar, Dinesh, additional, Bhatia, Shashi Kant, additional, and Kuča, Kamil, additional

Published
2020
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35. Detection of Bacterial Pathogens and Antibiotic Residues in Chicken Meat: A Review

Author

Kumar, Harsh, primary, Bhardwaj, Kanchan, additional, Kaur, Talwinder, additional, Nepovimova, Eugenie, additional, Kuča, Kamil, additional, Kumar, Vinod, additional, Bhatia, Shashi Kant, additional, Dhanjal, Daljeet Singh, additional, Chopra, Chirag, additional, Singh, Reena, additional, Guleria, Shivani, additional, Bhalla, Tek Chand, additional, Verma, Rachna, additional, and Kumar, Dinesh, additional

Published
2020
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36. Understanding of Colistin Usage in Food Animals and Available Detection Techniques: A Review

Author

Kumar, Harsh, primary, Chen, Bing-Huei, additional, Kuca, Kamil, additional, Nepovimova, Eugenie, additional, Kaushal, Ankur, additional, Nagraik, Rupak, additional, Bhatia, Shashi Kant, additional, Dhanjal, Daljeet Singh, additional, Kumar, Vinod, additional, Kumar, Anil, additional, Upadhyay, Navneet Kumar, additional, Verma, Rachna, additional, and Kumar, Dinesh, additional

Published
2020
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37. Herbicide Glyphosate: Toxicity and Microbial Degradation

Author

Singh, Simranjeet, primary, Kumar, Vijay, additional, Gill, Jatinder Pal Kaur, additional, Datta, Shivika, additional, Singh, Satyender, additional, Dhaka, Vaishali, additional, Kapoor, Dhriti, additional, Wani, Abdul Basit, additional, Dhanjal, Daljeet Singh, additional, Kumar, Manoj, additional, Harikumar, S. L., additional, and Singh, Joginder, additional

Published
2020
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40. Emerging trends in the novel drug delivery approaches for the treatment of lung cancer

Author

Sharma, Parvarish, primary, Mehta, Meenu, additional, Dhanjal, Daljeet Singh, additional, Kaur, Simran, additional, Gupta, Gaurav, additional, Singh, Harjeet, additional, Thangavelu, Lakshmi, additional, Rajeshkumar, S., additional, Tambuwala, Murtaza, additional, Bakshi, Hamid A., additional, Chellappan, Dinesh Kumar, additional, Dua, Kamal, additional, and Satija, Saurabh, additional

Published
2019
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43. Antioxidant Functionalized Nanoparticles: A Combat against Oxidative Stress.

Author

Kumar H, Bhardwaj K, Nepovimova E, Kuča K, Dhanjal DS, Bhardwaj S, Bhatia SK, Verma R, and Kumar D

Abstract

Numerous abiotic stresses trigger the overproduction of reactive oxygen species (ROS) that are highly toxic and reactive. These ROS are known to cause damage to carbohydrates, DNA, lipids and proteins, and build the oxidative stress and results in the induction of various diseases. To resolve this issue, antioxidants molecules have gained significant attention to scavenge these free radicals and ROS. However, poor absorption ability, difficulty in crossing the cell membranes and degradation of these antioxidants during delivery are the few challenges associated with both natural and synthetic antioxidants that limit their bioavailability. Moreover, the use of nanoparticles as an antioxidant is overlooked, and is limited to a few nanomaterials. To address these issues, antioxidant functionalized nanoparticles derived from various biological origin have emerged as an important alternative, because of properties like biocompatibility, high stability and targeted delivery. Algae, bacteria, fungi, lichens and plants are known as the producers of diverse secondary metabolites and phenolic compounds with extraordinary antioxidant properties. Hence, these compounds could be used in amalgamation with biogenic derived nanoparticles (NPs) for better antioxidant potential. This review intends to increase our knowledge about the antioxidant functionalized nanoparticles and the mechanism by which antioxidants empower nanoparticles to combat oxidative stress.

Published
2020
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