1. HYDROGEL FORMULATION FROM CALOTROPIS GIGANTEA PLANT EXTRACT AGAINST FOOT ULCER CAUSING BACTERIA IN DIABETES
- Author
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Ramachandran Am, Senthil Prabhu S, Varsha Tk, Rengaramanujam J, Karthik Sundaram S, Mahenthiren R, and Devakumar J
- Subjects
Pharmacology ,biology ,Traditional medicine ,business.industry ,Pharmaceutical Science ,biology.organism_classification ,medicine.disease ,Diabetes mellitus ,Medicine ,Pharmacology (medical) ,Foot ulcers ,business ,Calotropis gigantea ,Bacteria - Abstract
Objective: The objective of present study was to develop hydrogel formulations loaded with Calotropis gigantea leaves extract. Methods: The prepared hydrogel formulations were compliance with their color, odor, homogeneity, pH, and spreadability. Results: As all the formulations were complies with the all parameters and it can be suggest as a Good antibacterial gel. It is evident that, ethanolic extract of Calotropis gigantea showed a maximum inhibitory zone against bacteria associated with foot ulcer. Conclusions: The In vitro studies showed a quantity dependent increase in antibacterial activity against foot ulcer causing bacteria, a contraction which is higher than that produced by the control groups. These contractions were statistically significant (p
- Published
- 2021