33 results on '"Creemers, John W.M."'
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2. The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune tolerance
3. Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function
4. Bone-derived C-terminal FGF23 cleaved peptides increase iron availability in acute inflammation
5. Proprotein convertase furin regulates osteocalcin and bone endocrine function
6. Loss of hypothalamic Furin affects POMC to proACTH cleavage and feeding behavior in high-fat diet-fed mice
7. Impaired Islet Function in Commonly Used Transgenic Mouse Lines due to Human Growth Hormone Minigene Expression
8. Whole-Exome Sequencing of 677 Unrelated Aneurysm Patients Identifies Multiple Rare Variants of the Proprotein Convertase Furin Causing Impaired TGFB Signaling
9. Human Growth Hormone in Transgenesis: A Growing Problem?
10. Role of furin in granular acidification in the endocrine pancreas: identification of the V-ATPase subunit Ac45 as a candidate substrate
11. Deletion of PREPL, a gene encoding a putative serine oligopeptidase, in patients with hypotonia-cystinuria syndrome
12. Loss of Furin in β-Cells Induces an mTORC1-ATF4 Anabolic Pathway That Leads to β-Cell Dysfunction
13. Heterozygous Mutations Causing Partial Prohormone Convertase 1 Deficiency Contribute to Human Obesity
14. SCAMP5, NBEA and AMISYN: three candidate genes for autism involved in secretion of large dense-core vesicles
15. Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency
16. A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism
17. Loss of in β-Cells Induces an mTORC1-ATF4 Anabolic Pathway That Leads to β-Cell Dysfunction.
18. Functional and clinical relevance of novel and known PCSK1 variants for childhood obesity and glucose metabolism
19. PREPL deficiency: delineation of the phenotype and development of a functional blood assay
20. The Paired Basic Amino Acid-cleaving Enzyme 4 (PACE4) Is Involved in the Maturation of Insulin Receptor Isoform B
21. Phlorizin Pretreatment Reduces Acute Renal Toxicity in a Mouse Model for Diabetic Nephropathy
22. Curcumin affects proprotein convertase activity: Elucidation of the molecular and subcellular mechanism
23. Abstract 4627: Generation and characterization of non-competitive furin-inhibiting nanobodies
24. Internalization of Proprotein Convertase PC7 from Plasma Membrane Is Mediated by a Novel Motif
25. Limited Redundancy of the Proprotein Convertase Furin in Mouse Liver
26. Proteolytic Processing of Familial British Dementia-associated BRI Variants
27. Processing of β-Secretase by Furin and Other Members of the Proprotein Convertase Family
28. Binding of BiP to the Processing Enzyme Lymphoma Proprotein Convertase Prevents Aggregation, but Slows Down Maturation
29. Biosynthesis, Distinct Post-translational Modifications, and Functional Characterization of Lymphoma Proprotein Convertase
30. Human lactase-phlorizin hydrolase is not processed by furin, PC1/PC3, PC2, PACE4 and PC5/PC6A of the family of subtilisin-like proprotein processing proteases
31. Endoproteolytic Cleavage of Its Propeptide Is a Prerequisite for Efficient Transport of Furin Out of the Endoplasmic Reticulum
32. Proprotein processing activity and cleavage site selectivity of the Kex2‐like endoprotease PACE4
33. Expression in human lung tumor cells of the proprotein processing enzyme PC1/PC3 Cloning and primary sequence of a 5 kb cDNA
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