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1. Fatal Case of Diphtheria and Risk for Reemergence, Singapore

Author

Lai, Yingqi, Purnima, Parthasarathy, Ho, Marc, Ang, Michelle, Deepak, Rama N., Chew, Ka Lip, Vasoo, Shawn, Capulong, Dimatatac F., and Lee, Vernon

Subjects
Health aspects, Bacterial proteins -- Health aspects, Migrant labor -- Health aspects, Respiratory tract diseases -- Health aspects, Public health -- Health aspects, Vaccination -- Health aspects, Diphtheria -- Health aspects, Diphtheria toxoid -- Health aspects, Medical schools -- Health aspects, Medical colleges -- Health aspects, DPT vaccine -- Health aspects
Abstract

Diphtheria is an acute respiratory disease caused by infection with Corynebacterium diphtheriae. Casefatality rates for respiratory diphtheria reached 50% in epidemics in the 1880s and remain [approximately equal to]5%-10% even [...]

Published
2018
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2. Fatal Case of Diphtheria and Risk for Reemergence, Singapore.

Author

Yingqi Lai, Purnima, Parthasarathy, Ho, Marc, Ang, Michelle, Deepak, Rama N., Ka Lip Chew, Vasoo, Shawn, Capulong, Dimatatac F., Lee, Vernon, Lai, Yingqi, and Chew, Ka Lip

Subjects
DIPHTHERIA, MIGRANT labor, IMMUNIZATION, RESPIRATORY infections, CORYNEBACTERIUM diphtheriae, COMMUNICABLE disease diagnosis, PREVENTION of communicable diseases, COMMUNICABLE disease epidemiology, BACTERIAL vaccines, DISEASE complications, BIOLOGICAL evolution, GRAM-positive bacteria, PUBLIC health, PUBLIC health surveillance, TRAVEL, TREATMENT effectiveness, CONTACT tracing, INFECTIOUS disease transmission
Abstract

We report a fatal autochthonous diphtheria case in a migrant worker in Singapore. This case highlights the risk for individual cases in undervaccinated subpopulations, despite high vaccination coverage in the general population. Prompt implementation of public health measures and maintaining immunization coverage are critical to prevent reemergence of diphtheria. [ABSTRACT FROM AUTHOR]

Published
2018
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