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1. Efficacy of a topical formulation containing eprinomectin, esafoxolaner and praziquantel (NexGard® Combo) in the treatment of natural respiratory capillariosis of cats

Author

Di Cesare Angela, Morganti Giulia, Vignoli Massimo, Colombo Mariasole, Veronesi Fabrizia, Bufalari Antonello, Tielemans Eric, Beugnet Frederic, and Traversa Donato

Subjects
eucoleus aerophilus, capillaria aerophila, cats, pulmonary capillariosis, eprinomectin, treatment, Infectious and parasitic diseases, RC109-216
Abstract

Feline pulmonary capillariosis is a significant disorder due to its distribution and clinical impact. This study evaluated the safety and efficacy of two administrations 28 days apart of a topical solution containing esafoxolaner, eprinomectin and praziquantel (NexGard® Combo) in treating Eucoleus aerophilus (syn. Capillaria aerophila) infection in naturally infected cats. Cats were allocated to two groups: G1 cats (n = 23) received two treatments at study days (SDs) 0 and 28 (±2) and were evaluated for 6 weeks, and G2 cats (n = 17) served as a negative control for 6 weeks and were then treated twice on SDs 42 (±2) and 70 (±2), allowing for an additional 6-week assessment of efficacy. Each cat was subjected to McMaster coproscopy at SDs −7/0, 28 (±2) and 42 (±2) for both groups, 70 (±2) and 84 (±2) only for G2. Clinical examination and chest radiographic images were performed at SDs 0, 28 (±2) and 42 (±2) for G1 and G2, 70 (±2) and 84 (±2) only for G2. The comparison of EPG (eggs per gram of feces), clinical (CS), and radiographic scores (RS) at each time-point was used as a criterion. The efficacy based on the EPG reduction was 99.5% (G1) and 100% (G2) after two administrations of NexGard® Combo 2 weeks apart. At SD 0, no significant differences for CS and RS were recorded between G1 and G2, while a significant reduction (p

Published
2024
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2. Dog Aging: A Comprehensive Review of Molecular, Cellular, and Physiological Processes

Author

Gabriella Guelfi, Camilla Capaccia, Martina Tedeschi, Antonello Bufalari, Leonardo Leonardi, Beniamino Cenci-Goga, and Margherita Maranesi

Subjects
physiological decline, aging dog, aging hallmarks, epigenetic changes, Cytology, QH573-671
Abstract

The aging process is a multifactorial biological phenomenon starting at birth and persisting throughout life, characterized by a decline in physiological functions and adaptability. This decline results in the diminished capacity of aging organisms to respond to environmental changes and stressors, leading to reduced efficiency in metabolic, immune, and hormonal functions. As behavioral flexibility wanes, older individuals face longer recovery times and increased vulnerability to diseases. While early research proposed nine core hallmarks of mammalian aging, recent studies have expanded this framework to twelve key characteristics: epigenetic changes, genomic instability, telomere shortening, loss of proteostasis, altered metabolism, mitochondrial dysfunction, cellular senescence, disrupted intercellular communication, stem cell depletion, immune system dysfunction, accumulation of toxic metabolites, and dysbiosis. Given the growing interest in the aging area, we propose to add a new hallmark: impaired water homeostasis. This potential hallmark could play a critical role in aging processes and might open new directions for future research in the field. This review enhances our understanding of the physiological aspects of aging in dogs, suggesting new clinical intervention strategies to prevent and control issues that may arise from the pathological degeneration of these hallmarks.

Published
2024
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3. From Gene to Protein: Unraveling the Reproductive Blueprint of Male Grey Squirrels via Nerve Growth Factor (NGF) and Cognate Receptors

Author

Francesca Mercati, Gabriella Guelfi, Antonello Bufalari, Cecilia Dall’Aglio, Chiara Suvieri, Paolo Cocci, Francesco Alessandro Palermo, Polina Anipchenko, Camilla Capaccia, Beniamino Cenci-Goga, Massimo Zerani, and Margherita Maranesi

Subjects
grey squirrel, NGF, P75NTR, NTRK1, testis, reproductive phases, Veterinary medicine, SF600-1100, Zoology, QL1-991
Abstract

The grey squirrel, an invasive species, threatens the Eurasian red squirrel’s conservation, particularly in Umbria, Italy. Understanding its reproductive biology is essential to limiting its reproductive success. This study investigates the NGF system and its receptors (NTRK1 and p75NTR) in the testes of male grey squirrels, following prior research on female reproductive biology. NGF plays a role in testicular morphogenesis and spermiogenesis in animals and humans. As part of the LIFE Project U-SAVEREDS, eighteen squirrels were captured and classified into three morphotypes (immature, pubertal, and active spermatogenesis). NGF and its receptors were analyzed using real-time PCR, western blotting, immunohistochemistry, and plasma levels measured via ELISA. NGF qPCR expression levels were significantly higher during puberty compared to the immature and spermatogenesis stages (p < 0.01). Immunohistochemistry revealed NGF in Leydig cells, with stronger staining in pubertal and mature squirrels, while NTRK1 was found in Leydig cells in immature squirrels and germ cells in pubertal and mature ones. NGF receptors were observed in Sertoli cells in pubertal and mature squirrels. Plasma NGF levels showed a significant upregulation in pubertal squirrels (135.80 ± 12 pg/mL) compared to those in the immature (25.60 ± 9.32 pg/mL) and spermatogenesis stages (34.20 ± 6.06 pg/mL), with a p value < 0.01. The co-localization of NGF and its receptors suggests that NGF, produced by Leydig cells, regulates testis development and reproductive success through autocrine or paracrine mechanisms, potentially involving an unidentified pathway.

Published
2024
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5. Comparison between the effects of epidural lidocaine, tramadol, and lidocaine–tramadol on postoperative pain in cats undergoing elective orchiectomy

Author

Cecilia Vullo, Annastella Falcone, Gabriele Marino, Salvatore Monti, Adolfo Maria Tambella, Antonello Bufalari, and Giuseppe Catone

Subjects
Analgesia, Cats, Epidural anesthesia, Lidocaine, Orchiectomy, Tramadol, Veterinary medicine, SF600-1100
Abstract

Abstract Background In veterinary clinical practice, orchiectomy is one of the most common surgical procedures for cats and is performed mainly in young animals. The purpose of this study was to compare three different epidural (EP) analgesic protocols used in cats undergoing orchiectomy in order to determine which protocol resulted in superior outcomes in terms of perioperative analgesia. Twenty-one client-owned male cats were premedicated with a combination of dexmedetomidine (10 µg/kg) and midazolam (0.2 mg/kg) injected intramuscularly. Anesthesia was induced intravenously with propofol. Cats were randomly divided in three treatment groups of seven animals each: Group L received EP lidocaine (2 mg/kg), Group T received EP tramadol (1 mg/kg), and Group LT received EP lidocaine (2 mg/kg) plus tramadol (1 mg/kg). The post-operative pain level was assessed using two different scales: the Glasgow Composite Measure Pain Scale-Feline (CMPS-F) and the Feline Grimace Scale (FGS). Rescue analgesia was administered when the CMPS-F total score was ≥5 or the FGS total score was ≥4. Results No adverse effects related to tramadol or lidocaine were observed. Based on post-operative pain assessments, significant differences between groups were observed according to both pain scoring systems. In particular, in Group LT, the CMPS-F and FGS scores decreased significantly in the first six hours following castration. Conclusions Based on our results, EP lidocaine plus tramadol provided the best post-operative analgesic effects in cats submitted to orchiectomy lasting 6 h and could also be a choice to consider for longer surgical procedures.

Published
2023
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6. Genome-wide expression of the residual lung reacting to experimental Pneumonectomy

Author

Valerio Napolioni, Fortunato Bianconi, Rossella Potenza, Francesco M. Carpi, Vienna Ludovini, Matteo Picciolini, Francesca R. Tofanetti, Antonello Bufalari, Stefano Pallotti, Camilla Poggi, Marco Anile, Niccolò Daddi, Federico Venuta, Francesco Puma, and Jacopo Vannucci

Subjects
Differentially expressed genes, Experimental Pneumonectomy, Genome-wide expression, Lung, Pig, Pulmonary regeneration, Biotechnology, TP248.13-248.65, Genetics, QH426-470
Abstract

Abstract Background Acute or chronic irreversible respiratory failure may occur in patients undergoing pneumonectomy. Aim of this study was to determine transcriptome expression changes after experimental pneumonectomy in swine model. Experimental left pneumonectomy was performed in five pigs under general anaesthesia. Both the resected and the remaining lung, after 60 post-operative completely uneventful days, underwent genome-wide bulk RNA-Sequencing (RNA-Seq). Results Histological analysis showed dilation of air spaces and rupture of interalveolar septa. In addition, mild inflammation, no fibrosis, radial stretch of the bronchus, strong enlargement of airspaces and thinning of the blood supply were observed. Bioinformatic analyses of bulk RNA-Seq data identified 553 Differentially Expressed Genes (DEGs) at adjusted P-value below 0.001, between pre- and post-pneumonectomy. The top 10 up-regulated DEGs were Edn1, Areg, Havcr2, Gadd45g, Depp1, Cldn4, Atf3, Myc, Gadd45b, Socs3; the top 10 down-regulated DEGs were Obscn, Cdkn2b, ENSSSCG00000015738, Prrt2, Amer1, Flrt3, Efnb2, Tox3, Znf793, Znf365. Leveraging digital cytometry tools, no difference in cellular abundance was found between the two experimental groups, while the analysis of cell type-specific gene expression patterns highlighted a striking predominance of macrophage-specific genes among the DEGs. DAVID-based gene ontology analysis showed a significant enrichment of “Extrinsic apoptotic signaling pathway” (FDR q = 7.60 × 10− 3) and “Response to insulin” (FDR q = 7.60 × 10− 3) genes, along with an enrichment of genes involved as “Negative regulators of DDX58/IFIH1 signaling” (FDR q = 7.50 × 10− 4) found by querying the REACTOME pathway database. Gene network analyses indicated a general dysregulation of gene inter-connections. Conclusion This translational genomics study highlighted the existence both of individual genes, mostly dysregulated in certain cellular populations (e.g., macrophages), and gene-networks involved in pulmonary reaction after left pneumonectomy. Their involvement in lung homeostasis is largely supported by previous studies, carried out both in humans and in other animal models (under homeostatic or disease-related conditions), that adopted candidate-gene approaches. Overall, the present findings represent a preliminary assessment for future, more focused, studies on compensatory lung adaptation, pulmonary regeneration and functional reload.

Published
2021
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7. Palliative repeated electroporations of oral tumours in dogs: A case series

Author

Giulia Moretti, Alfredo Dentini, Francesca Beccati, Rolando Arcelli, Irene Di Matteo, Giuseppe Giovannini, and Antonello Bufalari

Subjects
electrochemotherapy, oral cavity tumour, dog, repeated electroporations, neoplasia, oncology, Veterinary medicine, SF600-1100
Abstract

Electrochemotherapy (ECT) is a highly developed treatment for many solid tumours that provides good local control in 80% of neoplasms in dogs. ECT can be used to treat different types of tumours, particularly as an innovative approach for non-resectable masses. As reported in the literature, electroporation-based treatments are safe, simple, fast and cost-effective treatment alternatives for selected oral and maxillofacial tumours not involving the bone in dogs (e.g., small squamous cell carcinoma or malignant melanoma). In this descriptive retrospective paper, the authors describe the outcome of various types of oral tumours treated with ECT as a palliative first line treatment or as a rescue treatment in dogs with local tumour recurrence. Nineteen dogs were included and treated with at least one session of three electroporations coupled with intravenous administration of bleomycin every 21 days. Tumour size, localization, histotype, stage, recurrence, solid tumour response evaluation criteria (RECIST), local toxicity, progression free survival (PFS) and median survival time (MST) were evaluated. The small population did not allow the analysis of the ECT response by comparing different tumour types; further studies with a larger caseload are needed. However, all dogs, despite the low MST, showed a good local response to treatment with a rapid improvement in quality of life from the first ECT application; no side effects attributable to chemotherapy have been detected and toxicity due to the electroporation was minimal and well tolerated in all dogs.

Published
2022
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8. Dog Aging: A Comprehensive Review of Molecular, Cellular, and Physiological Processes.

Author

Guelfi, Gabriella, Capaccia, Camilla, Tedeschi, Martina, Bufalari, Antonello, Leonardi, Leonardo, Cenci-Goga, Beniamino, and Maranesi, Margherita

Subjects
PHENOMENOLOGICAL biology, OLDER people, CELLULAR aging, AGE, CELL communication, TELOMERES
Abstract

The aging process is a multifactorial biological phenomenon starting at birth and persisting throughout life, characterized by a decline in physiological functions and adaptability. This decline results in the diminished capacity of aging organisms to respond to environmental changes and stressors, leading to reduced efficiency in metabolic, immune, and hormonal functions. As behavioral flexibility wanes, older individuals face longer recovery times and increased vulnerability to diseases. While early research proposed nine core hallmarks of mammalian aging, recent studies have expanded this framework to twelve key characteristics: epigenetic changes, genomic instability, telomere shortening, loss of proteostasis, altered metabolism, mitochondrial dysfunction, cellular senescence, disrupted intercellular communication, stem cell depletion, immune system dysfunction, accumulation of toxic metabolites, and dysbiosis. Given the growing interest in the aging area, we propose to add a new hallmark: impaired water homeostasis. This potential hallmark could play a critical role in aging processes and might open new directions for future research in the field. This review enhances our understanding of the physiological aspects of aging in dogs, suggesting new clinical intervention strategies to prevent and control issues that may arise from the pathological degeneration of these hallmarks. [ABSTRACT FROM AUTHOR]

Published
2024
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9. From Gene to Protein: Unraveling the Reproductive Blueprint of Male Grey Squirrels via Nerve Growth Factor (NGF) and Cognate Receptors.

Author

Mercati, Francesca, Guelfi, Gabriella, Bufalari, Antonello, Dall'Aglio, Cecilia, Suvieri, Chiara, Cocci, Paolo, Palermo, Francesco Alessandro, Anipchenko, Polina, Capaccia, Camilla, Cenci-Goga, Beniamino, Zerani, Massimo, and Maranesi, Margherita

Subjects
NERVE growth factor, TAMIASCIURUS, LEYDIG cells, SERTOLI cells, SPERMIOGENESIS in animals, SPERMATOGENESIS, PUBERTY
Abstract

Simple Summary: The grey squirrel (Sciurus carolinensis) is an invasive species threatening the Eurasian red squirrel in Umbria, Italy. Understanding its reproductive biology is crucial for managing its population. Based on previous research on female grey squirrels, this study investigates the nerve growth factor (NGF) system and its receptors in the testes of male grey squirrels. Eighteen squirrels were classified into immature, pubertal, and active spermatogenesis. Results showed an increased NGF level in pubertal squirrels. Immunohistochemistry identified NGF in Leydig cells, with stronger staining in pubertal and mature subjects. NTRK1 was found in the Leydig cells of immature squirrels and the germ cells of pubertal and mature ones. NGF receptors were also observed in Sertoli cells. These findings suggest that NGF plays a key role in testis development and reproductive success through autocrine or paracrine mechanisms, highlighting its importance in managing this invasive species. The grey squirrel, an invasive species, threatens the Eurasian red squirrel's conservation, particularly in Umbria, Italy. Understanding its reproductive biology is essential to limiting its reproductive success. This study investigates the NGF system and its receptors (NTRK1 and p75NTR) in the testes of male grey squirrels, following prior research on female reproductive biology. NGF plays a role in testicular morphogenesis and spermiogenesis in animals and humans. As part of the LIFE Project U-SAVEREDS, eighteen squirrels were captured and classified into three morphotypes (immature, pubertal, and active spermatogenesis). NGF and its receptors were analyzed using real-time PCR, western blotting, immunohistochemistry, and plasma levels measured via ELISA. NGF qPCR expression levels were significantly higher during puberty compared to the immature and spermatogenesis stages (p < 0.01). Immunohistochemistry revealed NGF in Leydig cells, with stronger staining in pubertal and mature squirrels, while NTRK1 was found in Leydig cells in immature squirrels and germ cells in pubertal and mature ones. NGF receptors were observed in Sertoli cells in pubertal and mature squirrels. Plasma NGF levels showed a significant upregulation in pubertal squirrels (135.80 ± 12 pg/mL) compared to those in the immature (25.60 ± 9.32 pg/mL) and spermatogenesis stages (34.20 ± 6.06 pg/mL), with a p value < 0.01. The co-localization of NGF and its receptors suggests that NGF, produced by Leydig cells, regulates testis development and reproductive success through autocrine or paracrine mechanisms, potentially involving an unidentified pathway. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Interleukin-1 Beta (IL1B) and Nerve Growth Factor (NGF): Key Players in Rabbit Reproductive Regulation.

Author

Guelfi, Gabriella, Dall'Aglio, Cecilia, Bufalari, Antonello, Mercati, Francesca, Anipchenko, Polina, Capaccia, Camilla, Cocci, Paolo, Palermo, Francesco Alessandro, Acuti, Gabriele, Troisi, Alessandro, Tomassoni, Daniele, Boiti, Cristiano, Zerani, Massimo, and Maranesi, Margherita

Subjects
GENITALIA, NERVE growth factor, ENZYME-linked immunosorbent assay, SEMINAL vesicles, ANTIGEN presenting cells, MALE reproductive organs
Abstract

Several seminal plasma components, besides NGF, are implicated as ovulation-inducing factors in mammals. This study investigated the IL1B and its receptor IL1R1 in the testis (T), male accessory glands, prostate (P) and seminal vesicles (SV), and uterus (U) of adult rabbits using immunohistochemistry (IHC) and quantitative reverse transcription PCR (RT-qPCR). We also assessed the presence of IL1B in seminal plasma through Western blotting (WB) and examined the interaction between IL1B and NGF in vitro by measuring their production with enzyme-linked immunosorbent assay (ELISA) in the presence of NGF and IL1B alone or with their respective receptor antagonists. IHC revealed IL1B system expression in all reproductive organs studied, with IL1B and IL1R1 localized to the germinative epithelium of the T and the epithelial cells of the accessory glands and U. IL1B gene transcript levels were significantly higher (p < 0.01) in the P and SV compared to the T, while IL1R1 levels were significantly higher (p < 0.001) in the P compared to the other tissues, while IL1R1 levels were three times higher (p < 0.001) in the P. WB confirmed the presence of IL1B in seminal plasma with a 30–35 kDa band. The in vitro study demonstrated that IL1B increased (p < 0.05) basal NGF production in the U, whereas NGF had no effect on IL1B production. These findings provide evidence of the expression of the IL1B/IL1R1 system in both male and female rabbit reproductive tracts and suggest that IL1B in seminal plasma may influence uterine endocrine activity. The results propose a potential role for IL1B in ovulation, in conjunction with NGF, supporting that ovulation may involve inflammatory-like processes. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Mode-{I, III} multiaxial fatigue of welded joints in steel maritime structures: Effective notch stress based resistance incorporating strength and mechanism contributions

Author

Bufalari, G. (author), den Besten, J.H. (author), Kaminski, M.L. (author), Bufalari, G. (author), den Besten, J.H. (author), and Kaminski, M.L. (author)

Abstract

The response of maritime structures can be multiaxial, involving predominant mode-I and non-negligible mode-III components. Adopting a stress distribution formulation based effective notch stress as fatigue strength parameter for mixed mode-{I, III} multiaxial fatigue assessment purposes, a mode-I equivalent von Mises type of failure criterion has been established at the critical fracture plane. Counting includes a cycle-by-cycle non-proportionality measure and damage accumulation is based on a linear model. Distinguished mode specific and material characteristic strength and mechanism contributions in terms of respectively the resistance curve intercept and mean stress induced response ratio coefficient, resistance curve slope and material characteristic length, have been incorporated. Evaluating the mid-cycle fatigue resistance, the outperformance is impressive. The analysed multiaxial mode-{I, III} data fits the uniaxial mode-I reference data scatter band and a single resistance curve can be used for fatigue assessment., Ship Hydromechanics and Structures, Ship and Offshore Structures

Published
2024
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15. Mechanical design and manufacture of a boundary layer pump

Author

Bufalari Lapo, Anselmi Eduardo, Rinchi Mirko, Howard Kevin, Talluri Lorenzo, and Fiaschi Daniele

Subjects
Environmental sciences, GE1-350
Abstract

This paper describes the current efforts to develop and manufacture a first prototype for a boundary layer pump as a mean to assess future and more complex designs. Following an approach of “learning by doing”, a previous design was re-assessed from a mechanical/workshop point of view. Budget constraints and in-house manufacturing capabilities were taken into consideration to deliver a new design, suitable for quick production. Challenges such as disc holding, gap spacing, pump intake, discharge nozzles, and tolerances were addressed. Structural analysis has been conducted; where every single component has been modelled and sized accordingly to standard practices. As a support of structural analysis, FEM analysis was also performed with the aim of identifying, discussing, and fixing any potentially critical issues, particularly regarding the bolts holding together the discs into the power shaft. Finally, modal analysis was performed in order to test the dynamic response of the rotor: its critical frequencies would be far from the working range of the machine. This paper gives an overview of the critical issues to be taken into account during the mechanical design of boundary layer pump prototypes for different working fluids in the field of power generation and thermal management.

Published
2023
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17. Editorial: A review of canine soft tissue sarcomas: new insights in diagnostic and treatment measures.

Author

Moretti, Giulia and Bufalari, Antonello

Subjects
SARCOMA, MAST cell tumors, RETICULUM cell sarcoma, SOFT tissue tumors, SYNOVIOMA, SKIN tumors
Abstract

This editorial provides a comprehensive review of canine soft tissue sarcomas, discussing their classification, clinical characteristics, and treatment options. It highlights recent research on new diagnostic and therapeutic approaches, such as dynamic contrast-enhanced ultrasound and microbrachytherapy. The article also presents findings on electroporation-based treatments for oral tumors, which have shown to be safe and effective but require further standardization. Additionally, the text explores canine extraskeletal osteosarcoma and suggests potential diagnostic markers for osteosarcoma. The editorial concludes by emphasizing the importance of interdisciplinary collaboration and the need for further research in veterinary oncology. [Extracted from the article]

Published
2024
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19. Efficacy of a topical formulation containing eprinomectin, esafoxolaner and praziquantel (NexGard® Combo) in the treatment of natural respiratory capillariosis of cats.

Author

Di Cesare, Angela, Morganti, Giulia, Vignoli, Massimo, Colombo, Mariasole, Veronesi, Fabrizia, Bufalari, Antonello, Tielemans, Eric, Beugnet, Frederic, and Traversa, Donato

Abstract

Copyright of Parasite (1252607X) is the property of EDP Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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21. Left Threatened by Right: Political Intergroup Bias in the Contemporary Italian Context

Author

Michael Schepisi, Giuseppina Porciello, Ilaria Bufalari, Salvatore Maria Aglioti, and Maria Serena Panasiti

Subjects
political intergroup bias, ideological conflict hypothesis, personalized politics, perceived threat, entitativity, agentivity, Psychology, BF1-990
Abstract

Using different evaluation targets (i.e., politicians’ pictures, ideological words, items referring to features attributed to political ingroup/outgroup) we characterized the intergroup bias among political groups in the Italian context (Study 1-2-3) and tested a model that may account for the bias itself (Study 3). For all evaluation targets, left-wing participants - compared to right-wing participants – showed a greater intergroup bias, expressing more negative emotions toward the outgroup. The process was influenced by a greater perceived threat of the outgroup. Conversely, right-wing participants expressed the bias only when presented with ideological words. Our results provide a detailed description of how intergroup bias in Italy is differently expressed by the two ideological groups depending on the targets used to represent the political counterpart. Moreover, the results show that the stronger bias expressed by left-wing participants is driven by perceived threat of the outgroup.

Published
2019
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22. Effects of intraperitoneal injection of microencapsulated Sertoli cells on chronic and presymptomatic dystrophic mice

Author

Sara Chiappalupi, Giovanni Luca, Francesca Mancuso, Luca Madaro, Francesca Fallarino, Carmine Nicoletti, Mario Calvitti, Iva Arato, Giulia Falabella, Laura Salvadori, Antonio Di Meo, Antonello Bufalari, Stefano Giovagnoli, Riccardo Calafiore, Rosario Donato, and Guglielmo Sorci

Subjects
Computer applications to medicine. Medical informatics, R858-859.7, Science (General), Q1-390
Abstract

We report data about the effects of intraperitoneal (i.p.) injection of specific pathogen-free (SPF) porcine Sertoli cells (SeC) encapsulated into clinical grade alginate-based microcapsules (SeC-MC) on muscles of chronic and presymptomatic dystrophic, mdx mice. Mdx mouse is the best characterized animal model of Duchenne muscular dystrophy (DMD), an X-linked lethal myopathy due to mutation in the gene of dystrophin, which is crucial for myofiber integrity during muscle contraction. Our data show that three weeks after i.p. injection of SeC-MC significantly reduced adipose and fibrous tissue deposition, reduced macrophage infiltrate, and reduced numbers of damaged myofibers are found in muscles of 12-month-old mdx mice, which reproduce chronic DMD conditions. Compared with muscles of mock-treated mdx mice muscles of SeC-MC-treated mice show upregulation of the dystrophin paralogue, utrophin which is localized to the periphery of myofibers. Moreover, our data show that i.p. injection of SeC-MC into presymptomatic, 2-week-old mdx mice, although not fully preventing myofiber degeneration, results in protection against myofiber necrosis and muscle inflammation. Extensive discussion of these data can be found in Ref. [1].

Published
2015
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23. The lameness in a cryptorchid dog with intra-abdominal torsion of one of the two neoplastic testicles: a case report

Author

A. Bufalari, A. Proni, G. Moretti, A. Di Meo, and S. Pirico

Subjects
cryptorchidism, canine, limp, intestitial cell tumour, testicular torsion, meralgia paresthetica, Veterinary medicine, SF600-1100
Abstract

This report describes a case of hind limb lameness associated with intra-abdominal torsion of a neoplastic testicle in a dog. An 11-year-old, male, bilaterally cryptorchid dog was referred for third degree lameness in the left hind limb. An orthopaedic and radiographic examination did not reveal any alteration in the limb, whereas transabdominal palpation and ultrasonography showed the presence of retained gonads. The surgical procedure revealed a left testicular torsion adherent to the viscera and peritoneum in the ventral-caudal part of the abdomen. A few days after a bilateral orchiectomy, the lameness was completely resolved. Histopathological investigations allowed diagnosis of intestitial (Sertoli) cell tumours in both testicles. One of the two testes was twisted. Sertolioma often affects undescended testicles and causes additional clinical changes, due to estrogenic steroidogenesis. The hyper-oestrogenism is characterised by alopecia, feminisation, prostatic alteration and haematological disorders. However, in this case these clinical signs were not present. The aim of this case report is to highlight the correlation of the disease and the onset of limp, which is similar to what has been reported in human medicine in patients affected by meralgia paresthetica.

Published
2015
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26. Changes in surgicaL behaviOrs dUring the CoviD-19 pandemic. The SICE CLOUD19 Study

Author

Bracale, U, Podda, M, Castiglioni, S, Peltrini, R, Sartori, A, Arezzo, A, Corcione, F, Agresta, F, Antonucci, A, Zanframundo, C, Cavallo, F, Mazzarolo, G, Agrusa, A, Di Buono, G, Aldrighetti, L, Fiorentini, G, Lucianetti, A, Magnone, S, Alfieri, S, Rosa, F, Altomare, D, Picciariello, A, Parisi, A, Di Cintio, A, Amisano, M, Cravero, F, Ammendola, M, Ammerata, G, Anastasi, A, Canonico, G, Gattolin, A, Travaglio, E, De Palma, M, Angelini, P, Galante, F, Benevento, A, Rausei, S, Serao, A, Abbatini, F, Annecchiarico, M, Varricchio, A, Annessi, V, Tumiati, D, Annicchiarico, A, Mirabella, A, Marino, M, Spinelli, A, Braun, A, Santi, H, Romano, L, Antoniutti, M, Armellino, M, Argenio, G, Verzelli, A, Budassi, A, Baiocchi, G, Alfano, M, Balani, A, Barone, M, Baldazzi, G, Cassini, D, Canger, R, Zabbialini, G, Belli, A, Izzo, F, Bertolino, F, Brunetti, M, Bianco, F, Cappiello, A, Boccia, L, Boffi, B, Perna, F, Bonilauri, S, Frazzetta, G, Bordoni, P, Fleres, F, Borghi, F, Giraudo, G, Bottino, V, Canfora, A, Piccoli, F, Calligaris, L, Nipote, B, Nasti, A, Bufalari, A, Bettarini, F, Buononato, M, Greco, M, Calo, P, Medas, F, Cardamone, E, Castaldo, P, Carlini, M, Spoletini, D, De Nisco, C, Pulighe, F, Feo, C, Fabbri, N, Antropoli, C, Foroni, F, Carnazza, M, Ragazzi, S, Cassinotti, E, Boni, L, Catena, F, Giuffrida, M, Perrone, G, Ccotsoglou, C, Granieri, S, Ceccarelli, G, Bugiantella, W, Cedolini, C, Seriau, L, Cesari, M, Contine, A, Chiara, O, Cimbanassi, S, Cocozza, E, Berselli, M, Fantini, C, Costi, R, Casali, L, Morini, A, Crafa, F, Vanela, S, Curro, G, Orsini, V, Da Lio, C, Biral, M, Danelli, P, Guerci, C, Scala, D, Marino, G, De Carlis, L, Lauterio, A, De Giorgi, D, Sciannamea, G, De Manzini, N, Losurdo, P, Sangiuliano, N, Degiuli, M, Caterina, F, Del Rio, P, Bonati, E, Di Lernia, S, Ardizzone, M, Di Saverio, S, Franchi, C, Di Venere, B, Miglio, R, Cuccurullo, D, Sagnelli, C, Docimo, L, Tolone, S, Longoni, M, Faillace, G, Rondelli, F, Pennella, F, Colucci, V, Carfora, T, Muttillo, I, Picardi, B, Stefano, R, Campagnacci, R, Maurizi, A, Tricarico, F, Montagna, M, Amedeo, E, Scollica, M, Lauro, E, Laterza, E, Molinari, E, Berta, G, Bono, D, Fabozzi, M, Romano, M, Facci, E, Parini, D, Farfaglia, R, Arizzi, V, Farsi, M, Miranda, E, Fei, L, Flavio, G, Pirozzi, F, Sciuto, A, Ferrero, A, Palisi, M, Filauro, M, Barberis, A, Azzinnaro, A, Fiscon, V, Vigna, S, D'Ambra, M, Pontecorvi, E, Anania, G, Bombardini, C, Galizia, G, Auricchio, A, Cardella, F, Genna, M, Gentilli, S, Herald, N, Castagnoli, G, Bartoli, A, Gianotti, L, Garancini, M, Bellanova, G, Palazzo, P, De Palma, G, Milone, M, Ferrari, G, Magistro, C, Giuliani, A, Di Natale, G, Brisinda, G, Cavallaro, G, Sammarco, G, Gallo, G, Goletti, O, Macchini, D, Greco, V, Amoroso, V, Guercioni, G, Benedetti, M, Guzzo, G, Pata, F, Scandroglio, I, Roscio, F, Jovine, E, Lombardi, R, La Rocca, F, Di Capua, F, Lanci, C, Leli, R, Borasi, A, Lepiane, P, Balla, A, Liberatore, E, Morelli, L, Di Franco, G, Lucchi, A, Vittori, L, Bonavina, L, Asti, E, Maggioni, D, Martino, G, Manca, G, Delvecchio, A, Tedesco, M, Gambardella, D, Marafioti, S, De Marco, M, Guicciardi, M, Motta, M, Calgaro, M, Adamo, V, Guerrieri, M, Coletta, P, Ortenzi, M, Martines, G, Lantone, G, Martinotti, M, Fassardi, G, Castriconi, M, Squillante, S, De Luca, M, Pavanello, M, Di Marco, C, Ronconi, M, Casiraghi, S, Mazzaferro, V, Battiston, C, Perrotta, M, Ripa, C, Giancarlo, M, Panizzo, V, Millo, P, Contul, R, Ferraro, V, Molino, C, Crolla, E, Moretto, G, Bacchion, M, Morino, M, Allaix, M, Motterlini, E, Petracca, M, Muratore, A, Musella, M, Vitiello, A, Nardo, B, Crocco, V, Navarra, G, Lazzara, S, Cuoghi, M, Olmi, S, Oldani, A, Uccelli, M, Opocher, E, Giovenzana, M, De Paolis, P, Santarelli, M, Delrio, P, Carbone, F, Bianchi, P, Formisano, Capelli, P, Baldini, E, Festa, P, Mottola, A, Merola, G, Perrotta, N, Celiento, M, Personnettaz, E, Muzio, S, Petitti, T, Melchiorre, A, Piccoli, M, Pecchini, F, Frontali, A, Maffioli, A, Maida, P, Tammaro, P, Pignata, G, Andreuccetti, J, Pilone, V, Renzulli, M, Pintaldi, S, Ceretti, A, Mariani, N, Pisanu, A, Polastri, R, Maiello, F, Porcu, A, Perra, T, Mucilli, F, Troisi, R, Montalti, R, Scognamillo, F, Delogu, D, Galleano, R, Malerba, M, Salfi, R, Pisano, M, Sechi, R, Cillara, N, Ramuscello, S, De Leo, E, Restini, E, Tumolo, R, Cianci, P, Capuzzolo, S, Rizzo, M, Recordare, A, Santoro, R, Amodio, P, Rocca, A, Cecere, G, Romito, R, Portigliotti, L, Rosati, R, Elmore, U, Russello, D, Latteri, S, Costarella, S, Massa, S, Capasso, L, Santangelo, M, Sodo, M, Sarro, G, Rivolta, U, Scabini, S, Pertile, D, Selvaggi, F, Rossi, S, Pellino, G, Sganga, G, Fransvea, P, Testa, S, De Rosa, C, Siquini, W, Trana, C, Solej, M, Bolzon, S, Guerra, E, Stella, M, Ferrara, F, Stipa, F, Stringhi, E, Celotti, A, Taglietti, L, Del Giudice, R, Talarico, C, Ruggiero, M, Tirone, G, Romario, U, Petz, W, Caracino, V, Rossetti, V, Verza, L, Vescovi, L, Marini, M, Vettoretto, N, Botteri, E, Vincenti, L, Giannandrea, G, Viora, T, Maganuco, L, Veronesi, P, Zani, B, Zanus, G, Brizzolari, M, Zanzi, F, Guariniello, A, Zappa, M, Galfrascoli, E, Zonta, S, Oragano, L, Zuliani, W, Chiari, D, Bracale U., Podda M., Castiglioni S., Peltrini R., Sartori A., Arezzo A., Corcione F., Agresta F., Antonucci A., Zanframundo C., Cavallo F., Mazzarolo G., Agrusa A., Di Buono G., Aldrighetti L., Fiorentini G., Lucianetti A., Magnone S., Alfieri S., Rosa F., Altomare D. F., Picciariello A., Parisi A., Di Cintio A., Amisano M. F., Cravero F., Ammendola M., Ammerata G., Anastasi A., Canonico G., Gattolin A., Travaglio E., De Palma M., Angelini P., Galante F., Benevento A., Rausei S., Serao A., Abbatini F., Annecchiarico M., Varricchio A., Annessi V., Tumiati D., Annicchiarico A., Mirabella A., Marino M. V., Spinelli A., Braun A., Santi H. T., Romano L., Antoniutti M., Armellino M. F., Argenio G., Verzelli A., Budassi A., Baiocchi G., Alfano M. S., Balani A., Barone M., Baldazzi G., Cassini D., Canger R. C. B., Zabbialini G., Belli A., Izzo F., Bertolino F., Brunetti M., Bianco F., Cappiello A., Boccia L., Boffi B., Perna F., Bonilauri S., Frazzetta G., Bordoni P., Fleres F., Borghi F., Giraudo G., Bottino V., Canfora A., Piccoli F. B., Calligaris L., Nipote B., Nasti A. G., Bufalari A., Bettarini F., Buononato M., Greco M., Calo P. G., Medas F., Cardamone E., Castaldo P., Carlini M., Spoletini D., De Nisco C., Pulighe F., Feo C. V., Fabbri N., Antropoli C., Foroni F., Carnazza M., Ragazzi S., Cassinotti E., Boni L., Catena F., Giuffrida M., Perrone G., Ccotsoglou C., Granieri S., Ceccarelli G., Bugiantella W., Cedolini C., Seriau L., Cesari M., Contine A., Chiara O., Cimbanassi S., Cocozza E., Berselli M., Fantini C., Costi R., Casali L., Morini A., Crafa F., Vanela S., Curro G., Orsini V., Da Lio C., Biral M., Danelli P., Guerci C., Scala D., Marino G., De Carlis L., Lauterio A., De Giorgi D., Sciannamea G., De Manzini N., Losurdo P., Sangiuliano N., Degiuli M., Caterina F., Del Rio P., Bonati E., Di Lernia S., Ardizzone M. V. R., Di Saverio S., Franchi C., Di Venere B., Miglio R., Cuccurullo D., Sagnelli C., Docimo L., Tolone S., Longoni M., Faillace G., Rondelli F., Pennella F. P., Colucci V., Carfora T., Muttillo I. A., Picardi B., Stefano R., Campagnacci R., Maurizi A., Tricarico F., Montagna M., Amedeo E., Scollica M. C., Lauro E., Laterza E., Molinari E., Berta G., Bono D., Fabozzi M., Romano M., Facci E., Parini D., Farfaglia R., Arizzi V., Farsi M., Miranda E., Fei L., Flavio G., Pirozzi F., Sciuto A., Ferrero A., Palisi M., Filauro M., Barberis A., Azzinnaro A., Fiscon V., Vigna S., D'ambra M., Pontecorvi E., Anania G., Bombardini C., Galizia G., Auricchio A., Cardella F., Genna M., Gentilli S., Herald N., Castagnoli G., Bartoli A., Gianotti L., Garancini M., Bellanova G., Palazzo P., De Palma G., Milone M., Ferrari G., Magistro C., Giuliani A., Di Natale G., Brisinda G., Cavallaro G., Sammarco G., Gallo G., Goletti O., Macchini D., Greco V., Amoroso V., Guercioni G., Benedetti M., Guzzo G., Pata F., Scandroglio I., Roscio F., Jovine E., Lombardi R., La Rocca F., Di Capua F., Lanci C., Leli R., Borasi A., Lepiane P., Balla A., Liberatore E., Morelli L., Di Franco G., Lucchi A., Vittori L., Bonavina L., Asti E., Maggioni D., Martino G., Manca G., Delvecchio A., Tedesco M., Gambardella D., Marafioti S., De Marco M. L., Guicciardi M. A., Motta M., Calgaro M., Adamo V., Guerrieri M., Coletta P., Ortenzi M., Martines G., Lantone G., Martinotti M., Fassardi G., Castriconi M., Squillante S., De Luca M., Pavanello M., Di Marco C., Ronconi M., Casiraghi S., Mazzaferro V., Battiston C., Perrotta M., Ripa C., Giancarlo M., Panizzo V., Millo P., Contul R. B., Ferraro V., Molino C., Crolla E., Moretto G., Bacchion M., Morino M., Allaix M. E., Motterlini E., Petracca M., Muratore A., Musella M., Vitiello A., Nardo B., Crocco V., Navarra G., Lazzara S., Navarra G. G., Cuoghi M., Olmi S., Oldani A., Uccelli M., Opocher E., Giovenzana M., De Paolis P., Santarelli M., Delrio P., Carbone F., Bianchi P. P. G., Capelli P., Baldini E., Festa P., Mottola A., Merola G., Perrotta N., Celiento M., Personnettaz E., Muzio S., Petitti T., Melchiorre A., Piccoli M., Pecchini F., Frontali A., Maffioli A., Maida P., Tammaro P., Pignata G., Andreuccetti J., Pilone V., Renzulli M., Pintaldi S., Ceretti A. P., Mariani N. M., Pisanu A., Polastri R., Maiello F., Porcu A., Perra T., Mucilli F., Troisi R., Montalti R., Scognamillo F., Delogu D., Galleano R., Malerba M., Salfi R., Pisano M., Sechi R., Cillara N., Ramuscello S., De Leo E., Restini E., Tumolo R., Cianci P., Capuzzolo S., Rizzo M., Recordare A., Santoro R., Amodio P. M., Rocca A., Cecere G., Romito R., Portigliotti L., Rosati R., Elmore U., Russello D., Latteri S., Costarella S. M., Massa S., Capasso L., Santangelo M., Sodo M., Sarro G., Rivolta U., Scabini S., Pertile D., Selvaggi F., Rossi S., Pellino G., Sganga G., Fransvea P., Testa S., De Rosa C., Siquini W., Trana C., Solej M., Bolzon S., Guerra E., Stella M., Ferrara F., Stipa F., Stringhi E., Celotti A., Taglietti L., Del Giudice R., Talarico C. A., Ruggiero M., Tirone G., Romario U. F., Petz W., Caracino V., Rossetti V., Verza L. A., Vescovi L., Marini M., Vettoretto N., Botteri E., Vincenti L., Giannandrea G., Viora T., Maganuco L., Veronesi P., Zani B., Zanus G., Brizzolari M., Zanzi F., Guariniello A., Zappa M. A., Galfrascoli E., Zonta S., Oragano L., Zuliani W., Chiari D., Bracale, U, Podda, M, Castiglioni, S, Peltrini, R, Sartori, A, Arezzo, A, Corcione, F, Agresta, F, Antonucci, A, Zanframundo, C, Cavallo, F, Mazzarolo, G, Agrusa, A, Di Buono, G, Aldrighetti, L, Fiorentini, G, Lucianetti, A, Magnone, S, Alfieri, S, Rosa, F, Altomare, D, Picciariello, A, Parisi, A, Di Cintio, A, Amisano, M, Cravero, F, Ammendola, M, Ammerata, G, Anastasi, A, Canonico, G, Gattolin, A, Travaglio, E, De Palma, M, Angelini, P, Galante, F, Benevento, A, Rausei, S, Serao, A, Abbatini, F, Annecchiarico, M, Varricchio, A, Annessi, V, Tumiati, D, Annicchiarico, A, Mirabella, A, Marino, M, Spinelli, A, Braun, A, Santi, H, Romano, L, Antoniutti, M, Armellino, M, Argenio, G, Verzelli, A, Budassi, A, Baiocchi, G, Alfano, M, Balani, A, Barone, M, Baldazzi, G, Cassini, D, Canger, R, Zabbialini, G, Belli, A, Izzo, F, Bertolino, F, Brunetti, M, Bianco, F, Cappiello, A, Boccia, L, Boffi, B, Perna, F, Bonilauri, S, Frazzetta, G, Bordoni, P, Fleres, F, Borghi, F, Giraudo, G, Bottino, V, Canfora, A, Piccoli, F, Calligaris, L, Nipote, B, Nasti, A, Bufalari, A, Bettarini, F, Buononato, M, Greco, M, Calo, P, Medas, F, Cardamone, E, Castaldo, P, Carlini, M, Spoletini, D, De Nisco, C, Pulighe, F, Feo, C, Fabbri, N, Antropoli, C, Foroni, F, Carnazza, M, Ragazzi, S, Cassinotti, E, Boni, L, Catena, F, Giuffrida, M, Perrone, G, Ccotsoglou, C, Granieri, S, Ceccarelli, G, Bugiantella, W, Cedolini, C, Seriau, L, Cesari, M, Contine, A, Chiara, O, Cimbanassi, S, Cocozza, E, Berselli, M, Fantini, C, Costi, R, Casali, L, Morini, A, Crafa, F, Vanela, S, Curro, G, Orsini, V, Da Lio, C, Biral, M, Danelli, P, Guerci, C, Scala, D, Marino, G, De Carlis, L, Lauterio, A, De Giorgi, D, Sciannamea, G, De Manzini, N, Losurdo, P, Sangiuliano, N, Degiuli, M, Caterina, F, Del Rio, P, Bonati, E, Di Lernia, S, Ardizzone, M, Di Saverio, S, Franchi, C, Di Venere, B, Miglio, R, Cuccurullo, D, Sagnelli, C, Docimo, L, Tolone, S, Longoni, M, Faillace, G, Rondelli, F, Pennella, F, Colucci, V, Carfora, T, Muttillo, I, Picardi, B, Stefano, R, Campagnacci, R, Maurizi, A, Tricarico, F, Montagna, M, Amedeo, E, Scollica, M, Lauro, E, Laterza, E, Molinari, E, Berta, G, Bono, D, Fabozzi, M, Romano, M, Facci, E, Parini, D, Farfaglia, R, Arizzi, V, Farsi, M, Miranda, E, Fei, L, Flavio, G, Pirozzi, F, Sciuto, A, Ferrero, A, Palisi, M, Filauro, M, Barberis, A, Azzinnaro, A, Fiscon, V, Vigna, S, D'Ambra, M, Pontecorvi, E, Anania, G, Bombardini, C, Galizia, G, Auricchio, A, Cardella, F, Genna, M, Gentilli, S, Herald, N, Castagnoli, G, Bartoli, A, Gianotti, L, Garancini, M, Bellanova, G, Palazzo, P, De Palma, G, Milone, M, Ferrari, G, Magistro, C, Giuliani, A, Di Natale, G, Brisinda, G, Cavallaro, G, Sammarco, G, Gallo, G, Goletti, O, Macchini, D, Greco, V, Amoroso, V, Guercioni, G, Benedetti, M, Guzzo, G, Pata, F, Scandroglio, I, Roscio, F, Jovine, E, Lombardi, R, La Rocca, F, Di Capua, F, Lanci, C, Leli, R, Borasi, A, Lepiane, P, Balla, A, Liberatore, E, Morelli, L, Di Franco, G, Lucchi, A, Vittori, L, Bonavina, L, Asti, E, Maggioni, D, Martino, G, Manca, G, Delvecchio, A, Tedesco, M, Gambardella, D, Marafioti, S, De Marco, M, Guicciardi, M, Motta, M, Calgaro, M, Adamo, V, Guerrieri, M, Coletta, P, Ortenzi, M, Martines, G, Lantone, G, Martinotti, M, Fassardi, G, Castriconi, M, Squillante, S, De Luca, M, Pavanello, M, Di Marco, C, Ronconi, M, Casiraghi, S, Mazzaferro, V, Battiston, C, Perrotta, M, Ripa, C, Giancarlo, M, Panizzo, V, Millo, P, Contul, R, Ferraro, V, Molino, C, Crolla, E, Moretto, G, Bacchion, M, Morino, M, Allaix, M, Motterlini, E, Petracca, M, Muratore, A, Musella, M, Vitiello, A, Nardo, B, Crocco, V, Navarra, G, Lazzara, S, Cuoghi, M, Olmi, S, Oldani, A, Uccelli, M, Opocher, E, Giovenzana, M, De Paolis, P, Santarelli, M, Delrio, P, Carbone, F, Bianchi, P, Formisano, Capelli, P, Baldini, E, Festa, P, Mottola, A, Merola, G, Perrotta, N, Celiento, M, Personnettaz, E, Muzio, S, Petitti, T, Melchiorre, A, Piccoli, M, Pecchini, F, Frontali, A, Maffioli, A, Maida, P, Tammaro, P, Pignata, G, Andreuccetti, J, Pilone, V, Renzulli, M, Pintaldi, S, Ceretti, A, Mariani, N, Pisanu, A, Polastri, R, Maiello, F, Porcu, A, Perra, T, Mucilli, F, Troisi, R, Montalti, R, Scognamillo, F, Delogu, D, Galleano, R, Malerba, M, Salfi, R, Pisano, M, Sechi, R, Cillara, N, Ramuscello, S, De Leo, E, Restini, E, Tumolo, R, Cianci, P, Capuzzolo, S, Rizzo, M, Recordare, A, Santoro, R, Amodio, P, Rocca, A, Cecere, G, Romito, R, Portigliotti, L, Rosati, R, Elmore, U, Russello, D, Latteri, S, Costarella, S, Massa, S, Capasso, L, Santangelo, M, Sodo, M, Sarro, G, Rivolta, U, Scabini, S, Pertile, D, Selvaggi, F, Rossi, S, Pellino, G, Sganga, G, Fransvea, P, Testa, S, De Rosa, C, Siquini, W, Trana, C, Solej, M, Bolzon, S, Guerra, E, Stella, M, Ferrara, F, Stipa, F, Stringhi, E, Celotti, A, Taglietti, L, Del Giudice, R, Talarico, C, Ruggiero, M, Tirone, G, Romario, U, Petz, W, Caracino, V, Rossetti, V, Verza, L, Vescovi, L, Marini, M, Vettoretto, N, Botteri, E, Vincenti, L, Giannandrea, G, Viora, T, Maganuco, L, Veronesi, P, Zani, B, Zanus, G, Brizzolari, M, Zanzi, F, Guariniello, A, Zappa, M, Galfrascoli, E, Zonta, S, Oragano, L, Zuliani, W, Chiari, D, Bracale U., Podda M., Castiglioni S., Peltrini R., Sartori A., Arezzo A., Corcione F., Agresta F., Antonucci A., Zanframundo C., Cavallo F., Mazzarolo G., Agrusa A., Di Buono G., Aldrighetti L., Fiorentini G., Lucianetti A., Magnone S., Alfieri S., Rosa F., Altomare D. F., Picciariello A., Parisi A., Di Cintio A., Amisano M. F., Cravero F., Ammendola M., Ammerata G., Anastasi A., Canonico G., Gattolin A., Travaglio E., De Palma M., Angelini P., Galante F., Benevento A., Rausei S., Serao A., Abbatini F., Annecchiarico M., Varricchio A., Annessi V., Tumiati D., Annicchiarico A., Mirabella A., Marino M. V., Spinelli A., Braun A., Santi H. T., Romano L., Antoniutti M., Armellino M. F., Argenio G., Verzelli A., Budassi A., Baiocchi G., Alfano M. S., Balani A., Barone M., Baldazzi G., Cassini D., Canger R. C. B., Zabbialini G., Belli A., Izzo F., Bertolino F., Brunetti M., Bianco F., Cappiello A., Boccia L., Boffi B., Perna F., Bonilauri S., Frazzetta G., Bordoni P., Fleres F., Borghi F., Giraudo G., Bottino V., Canfora A., Piccoli F. B., Calligaris L., Nipote B., Nasti A. G., Bufalari A., Bettarini F., Buononato M., Greco M., Calo P. G., Medas F., Cardamone E., Castaldo P., Carlini M., Spoletini D., De Nisco C., Pulighe F., Feo C. V., Fabbri N., Antropoli C., Foroni F., Carnazza M., Ragazzi S., Cassinotti E., Boni L., Catena F., Giuffrida M., Perrone G., Ccotsoglou C., Granieri S., Ceccarelli G., Bugiantella W., Cedolini C., Seriau L., Cesari M., Contine A., Chiara O., Cimbanassi S., Cocozza E., Berselli M., Fantini C., Costi R., Casali L., Morini A., Crafa F., Vanela S., Curro G., Orsini V., Da Lio C., Biral M., Danelli P., Guerci C., Scala D., Marino G., De Carlis L., Lauterio A., De Giorgi D., Sciannamea G., De Manzini N., Losurdo P., Sangiuliano N., Degiuli M., Caterina F., Del Rio P., Bonati E., Di Lernia S., Ardizzone M. V. R., Di Saverio S., Franchi C., Di Venere B., Miglio R., Cuccurullo D., Sagnelli C., Docimo L., Tolone S., Longoni M., Faillace G., Rondelli F., Pennella F. P., Colucci V., Carfora T., Muttillo I. A., Picardi B., Stefano R., Campagnacci R., Maurizi A., Tricarico F., Montagna M., Amedeo E., Scollica M. C., Lauro E., Laterza E., Molinari E., Berta G., Bono D., Fabozzi M., Romano M., Facci E., Parini D., Farfaglia R., Arizzi V., Farsi M., Miranda E., Fei L., Flavio G., Pirozzi F., Sciuto A., Ferrero A., Palisi M., Filauro M., Barberis A., Azzinnaro A., Fiscon V., Vigna S., D'ambra M., Pontecorvi E., Anania G., Bombardini C., Galizia G., Auricchio A., Cardella F., Genna M., Gentilli S., Herald N., Castagnoli G., Bartoli A., Gianotti L., Garancini M., Bellanova G., Palazzo P., De Palma G., Milone M., Ferrari G., Magistro C., Giuliani A., Di Natale G., Brisinda G., Cavallaro G., Sammarco G., Gallo G., Goletti O., Macchini D., Greco V., Amoroso V., Guercioni G., Benedetti M., Guzzo G., Pata F., Scandroglio I., Roscio F., Jovine E., Lombardi R., La Rocca F., Di Capua F., Lanci C., Leli R., Borasi A., Lepiane P., Balla A., Liberatore E., Morelli L., Di Franco G., Lucchi A., Vittori L., Bonavina L., Asti E., Maggioni D., Martino G., Manca G., Delvecchio A., Tedesco M., Gambardella D., Marafioti S., De Marco M. L., Guicciardi M. A., Motta M., Calgaro M., Adamo V., Guerrieri M., Coletta P., Ortenzi M., Martines G., Lantone G., Martinotti M., Fassardi G., Castriconi M., Squillante S., De Luca M., Pavanello M., Di Marco C., Ronconi M., Casiraghi S., Mazzaferro V., Battiston C., Perrotta M., Ripa C., Giancarlo M., Panizzo V., Millo P., Contul R. B., Ferraro V., Molino C., Crolla E., Moretto G., Bacchion M., Morino M., Allaix M. E., Motterlini E., Petracca M., Muratore A., Musella M., Vitiello A., Nardo B., Crocco V., Navarra G., Lazzara S., Navarra G. G., Cuoghi M., Olmi S., Oldani A., Uccelli M., Opocher E., Giovenzana M., De Paolis P., Santarelli M., Delrio P., Carbone F., Bianchi P. P. G., Capelli P., Baldini E., Festa P., Mottola A., Merola G., Perrotta N., Celiento M., Personnettaz E., Muzio S., Petitti T., Melchiorre A., Piccoli M., Pecchini F., Frontali A., Maffioli A., Maida P., Tammaro P., Pignata G., Andreuccetti J., Pilone V., Renzulli M., Pintaldi S., Ceretti A. P., Mariani N. M., Pisanu A., Polastri R., Maiello F., Porcu A., Perra T., Mucilli F., Troisi R., Montalti R., Scognamillo F., Delogu D., Galleano R., Malerba M., Salfi R., Pisano M., Sechi R., Cillara N., Ramuscello S., De Leo E., Restini E., Tumolo R., Cianci P., Capuzzolo S., Rizzo M., Recordare A., Santoro R., Amodio P. M., Rocca A., Cecere G., Romito R., Portigliotti L., Rosati R., Elmore U., Russello D., Latteri S., Costarella S. M., Massa S., Capasso L., Santangelo M., Sodo M., Sarro G., Rivolta U., Scabini S., Pertile D., Selvaggi F., Rossi S., Pellino G., Sganga G., Fransvea P., Testa S., De Rosa C., Siquini W., Trana C., Solej M., Bolzon S., Guerra E., Stella M., Ferrara F., Stipa F., Stringhi E., Celotti A., Taglietti L., Del Giudice R., Talarico C. A., Ruggiero M., Tirone G., Romario U. F., Petz W., Caracino V., Rossetti V., Verza L. A., Vescovi L., Marini M., Vettoretto N., Botteri E., Vincenti L., Giannandrea G., Viora T., Maganuco L., Veronesi P., Zani B., Zanus G., Brizzolari M., Zanzi F., Guariniello A., Zappa M. A., Galfrascoli E., Zonta S., Oragano L., Zuliani W., and Chiari D.

Abstract

Background: The spread of the SARS-CoV2 virus, which causes COVID-19 disease, profoundly impacted the surgical community. Recommendations have been published to manage patients needing surgery during the COVID-19 pandemic. This survey, under the aegis of the Italian Society of Endoscopic Surgery, aims to analyze how Italian surgeons have changed their practice during the pandemic. Methods: The authors designed an online survey that was circulated for completion to the Italian departments of general surgery registered in the Italian Ministry of Health database in December 2020. Questions were divided into three sections: hospital organization, screening policies, and safety profile of the surgical operation. The investigation periods were divided into the Italian pandemic phases I (March–May 2020), II (June–September 2020), and III (October–December 2020). Results: Of 447 invited departments, 226 answered the survey. Most hospitals were treating both COVID-19-positive and -negative patients. The reduction in effective beds dedicated to surgical activity was significant, affecting 59% of the responding units. 12.4% of the respondents in phase I, 2.6% in phase II, and 7.7% in phase III reported that their surgical unit had been closed. 51.4%, 23.5%, and 47.8% of the respondents had at least one colleague reassigned to non-surgical COVID-19 activities during the three phases. There has been a reduction in elective (> 200 procedures: 2.1%, 20.6% and 9.9% in the three phases, respectively) and emergency (< 20 procedures: 43.3%, 27.1%, 36.5% in the three phases, respectively) surgical activity. The use of laparoscopy also had a setback in phase I (25.8% performed less than 20% of elective procedures through laparoscopy). 60.6% of the respondents used a smoke evacuation device during laparoscopy in phase I, 61.6% in phase II, and 64.2% in phase III. Almost all responders (82.8% vs. 93.2% vs. 92.7%) in each analyzed period did not modify or reduce the use of high-energ

Published
2021

27. Correction to: Changes in surgicaL behaviOrs dUring the CoviD-19 pandemic. The SICE CLOUD19 Study (Updates in Surgery, (2021), 73, 2, (731-744), 10.1007/s13304-021-01010-w)

Author

Bracale U., Bracale, U, Podda, M, Castiglioni, S, Peltrini, R, Sartori, A, Arezzo, A, Corcione, F, Agresta, F, Antonucci, A, Zanframundo, C, Cavallo, F, Mazzarolo, G, Agrusa, A, Di Buono, G, Aldrighetti, L, Fiorentini, G, Lucianetti, A, Magnone, S, Alfieri, S, Rosa, F, Altomare, D, Picciariello, A, Parisi, A, Di Cintio, A, Amisano, M, Cravero, F, Ammendola, M, Ammerata, G, Anastasi, A, Canonico, G, Gattolin, A, Travaglio, E, De Palma, M, Angelini, P, Galante, F, Benevento, A, Rausei, S, Serao, A, Abbatini, F, Annecchiarico, M, Varricchio, A, Annessi, V, Tumiati, D, Annicchiarico, A, Mirabella, A, Marino, M, Spinelli, A, Braun, A, Santi, H, Romano, L, Antoniutti, M, Armellino, M, Argenio, G, Verzelli, A, Budassi, A, Baiocchi, G, Alfano, M, Balani, A, Barone, M, Baldazzi, G, Cassini, D, Canger, R, Zabbialini, G, Belli, A, Izzo, F, Bertolino, F, Brunetti, M, Bianco, F, Cappiello, A, Boccia, L, Boffi, B, Perna, F, Bonilauri, S, Frazzetta, G, Bordoni, P, Fleres, F, Borghi, F, Giraudo, G, Bottino, V, Canfora, A, Piccoli, F, Calligaris, L, Nipote, B, Nasti, A, Bufalari, A, Bettarini, F, Buononato, M, Greco, M, Calo, P, Medas, F, Cardamone, E, Castaldo, P, Carlini, M, Spoletini, D, De Nisco, C, Pulighe, F, Feo, C, Fabbri, N, Antropoli, C, Foroni, F, Carnazza, M, Ragazzi, S, Cassinotti, E, Boni, L, Catena, F, Giuffrida, M, Perrone, G, Ccotsoglou, C, Granieri, S, Ceccarelli, G, Bugiantella, W, Cedolini, C, Seriau, L, Cesari, M, Contine, A, Chiara, O, Cimbanassi, S, Cocozza, E, Berselli, M, Fantini, C, Costi, R, Casali, L, Morini, A, Crafa, F, Vanela, S, Curro, G, Orsini, V, Da Lio, C, Biral, M, Danelli, P, Guerci, C, Scala, D, Marino, G, De Carlis, L, Lauterio, A, De Giorgi, D, Sciannamea, G, De Manzini, N, Losurdo, P, Sangiuliano, N, Degiuli, M, Caterina, F, Del Rio, P, Bonati, E, Di Lernia, S, Ardizzone, M, Di Saverio, S, Franchi, C, Di Venere, B, Miglio, R, Cuccurullo, D, Sagnelli, C, Docimo, L, Tolone, S, Longoni, M, Faillace, G, Rondelli, F, Pennella, F, Colucci, V, Carfora, T, Muttillo, I, Picardi, B, Stefano, R, Campagnacci, R, Maurizi, A, Tricarico, F, Montagna, M, Amedeo, E, Scollica, M, Lauro, E, Laterza, E, Molinari, E, Berta, G, Bono, D, Fabozzi, M, Romano, M, Facci, E, Parini, D, Farfaglia, R, Arizzi, V, Farsi, M, Miranda, E, Fei, L, Flavio, G, Pirozzi, F, Sciuto, A, Ferrero, A, Palisi, M, Filauro, M, Barberis, A, Azzinnaro, A, Fiscon, V, Vigna, S, D'Ambra, M, Pontecorvi, E, Anania, G, Bombardini, C, Galizia, G, Auricchio, A, Cardella, F, Genna, M, Gentilli, S, Herald, N, Castagnoli, G, Bartoli, A, Gianotti, L, Garancini, M, Bellanova, G, Palazzo, P, De Palma, G, Milone, M, Ferrari, G, Magistro, C, Giuliani, A, Di Natale, G, Brisinda, G, Cavallaro, G, Sammarco, G, Gallo, G, Goletti, O, Macchini, D, Greco, V, Amoroso, V, Guercioni, G, Benedetti, M, Guzzo, G, Pata, F, Scandroglio, I, Roscio, F, Jovine, E, Lombardi, R, La Rocca, F, Di Capua, F, Lanci, C, Leli, R, Borasi, A, Lepiane, P, Balla, A, Liberatore, E, Morelli, L, Di Franco, G, Lucchi, A, Vittori, L, Bonavina, L, Asti, E, Maggioni, D, Martino, G, Manca, G, Delvecchio, A, Tedesco, M, Gambardella, D, Marafioti, S, De Marco, M, Guicciardi, M, Motta, M, Calgaro, M, Adamo, V, Guerrieri, M, Coletta, P, Ortenzi, M, Martines, G, Lantone, G, Martinotti, M, Fassardi, G, Castriconi, M, Squillante, S, De Luca, M, Pavanello, M, Di Marco, C, Ronconi, M, Casiraghi, S, Mazzaferro, V, Battiston, C, Perrotta, M, Ripa, C, Giancarlo, M, Panizzo, V, Millo, P, Contul, R, Ferraro, V, Molino, C, Crolla, E, Moretto, G, Bacchion, M, Morino, M, Allaix, M, Motterlini, E, Petracca, M, Muratore, A, Musella, M, Vitiello, A, Nardo, B, Crocco, V, Navarra, G, Lazzara, S, Cuoghi, M, Olmi, S, Oldani, A, Uccelli, M, Opocher, E, Giovenzana, M, De Paolis, P, Santarelli, M, Delrio, P, Carbone, F, Bianchi, P, Formisano, G, Capelli, P, Baldini, E, Festa, P, Mottola, A, Merola, G, Perrotta, N, Celiento, M, Personnettaz, E, Muzio, S, Petitti, T, Melchiorre, A, Piccoli, M, Pecchini, F, Frontali, A, 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E, Vincenti, L, Giannandrea, G, Viora, T, Maganuco, L, Veronesi, P, Zani, B, Zanus, G, Brizzolari, M, Zanzi, F, Guariniello, A, Zappa, M, Galfrascoli, E, Zonta, S, Oragano, L, Zuliani, W, Chiari, D, Bracale U., Podda M., Castiglioni S., Peltrini R., Sartori A., Arezzo A., Corcione F., Agresta F., Antonucci A., Zanframundo C., Cavallo F., Mazzarolo G., Agrusa A., Di Buono G., Aldrighetti L., Fiorentini G., Lucianetti A., Magnone S., Alfieri S., Rosa F., Altomare D. F., Picciariello A., Parisi A., Di Cintio A., Amisano M. F., Cravero F., Ammendola M., Ammerata G., Anastasi A., Canonico G., Gattolin A., Travaglio E., De Palma M., Angelini P., Galante F., Benevento A., Rausei S., Serao A., Abbatini F., Annecchiarico M., Varricchio A., Annessi V., Tumiati D., Annicchiarico A., Mirabella A., Marino M. V., Spinelli A., Braun A., Santi H. T., Romano L., Antoniutti M., Armellino M. F., Argenio G., Verzelli A., Budassi A., Baiocchi G., Alfano M. S., Balani A., Barone M., Baldazzi G., Cassini D., Canger R. C. B., Zabbialini G., Belli A., Izzo F., Bertolino F., Brunetti M., Bianco F., Cappiello A., Boccia L., Boffi B., Perna F., Bonilauri S., Frazzetta G., Bordoni P., Fleres F., Borghi F., Giraudo G., Bottino V., Canfora A., Piccoli F. B., Calligaris L., Nipote B., Nasti A. G., Bufalari A., Bettarini F., Buononato M., Greco M., Calo P. G., Medas F., Cardamone E., Castaldo P., Carlini M., Spoletini D., De Nisco C., Pulighe F., Feo C. V., Fabbri N., Antropoli C., Foroni F., Carnazza M., Ragazzi S., Cassinotti E., Boni L., Catena F., Giuffrida M., Perrone G., Ccotsoglou C., Granieri S., Ceccarelli G., Bugiantella W., Cedolini C., Seriau L., Cesari M., Contine A., Chiara O., Cimbanassi S., Cocozza E., Berselli M., Fantini C., Costi R., Casali L., Morini A., Crafa F., Vanela S., Curro G., Orsini V., Da Lio C., Biral M., Danelli P., Guerci C., Scala D., Marino G., De Carlis L., Lauterio A., De Giorgi D., Sciannamea G., De Manzini N., Losurdo P., Sangiuliano N., Degiuli M., Caterina F., Del Rio P., Bonati E., Di Lernia S., Ardizzone M. V. R., Di Saverio S., Franchi C., Di Venere B., Miglio R., Cuccurullo D., Sagnelli C., Docimo L., Tolone S., Longoni M., Faillace G., Rondelli F., Pennella F. P., Colucci V., Carfora T., Muttillo I. A., Picardi B., Stefano R., Campagnacci R., Maurizi A., Tricarico F., Montagna M., Amedeo E., Scollica M. C., Lauro E., Laterza E., Molinari E., Berta G., Bono D., Fabozzi M., Romano M., Facci E., Parini D., Farfaglia R., Arizzi V., Farsi M., Miranda E., Fei L., Flavio G., Pirozzi F., Sciuto A., Ferrero A., Palisi M., Filauro M., Barberis A., Azzinnaro A., Fiscon V., Vigna S., D'ambra M., Pontecorvi E., Anania G., Bombardini C., Galizia G., Auricchio A., Cardella F., Genna M., Gentilli S., Herald N., Castagnoli G., Bartoli A., Gianotti L., Garancini M., Bellanova G., Palazzo P., De Palma G., Milone M., Ferrari G., Magistro C., Giuliani A., Di Natale G., Brisinda G., Cavallaro G., Sammarco G., Gallo G., Goletti O., Macchini D., Greco V., Amoroso V., Guercioni G., Benedetti M., Guzzo G., Pata F., Scandroglio I., Roscio F., Jovine E., Lombardi R., La Rocca F., Di Capua F., Lanci C., Leli R., Borasi A., Lepiane P., Balla A., Liberatore E., Morelli L., Di Franco G., Lucchi A., Vittori L., Bonavina L., Asti E., Maggioni D., Martino G., Manca G., Delvecchio A., Tedesco M., Gambardella D., Marafioti S., De Marco M. 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Longoni, M, Faillace, G, Rondelli, F, Pennella, F, Colucci, V, Carfora, T, Muttillo, I, Picardi, B, Stefano, R, Campagnacci, R, Maurizi, A, Tricarico, F, Montagna, M, Amedeo, E, Scollica, M, Lauro, E, Laterza, E, Molinari, E, Berta, G, Bono, D, Fabozzi, M, Romano, M, Facci, E, Parini, D, Farfaglia, R, Arizzi, V, Farsi, M, Miranda, E, Fei, L, Flavio, G, Pirozzi, F, Sciuto, A, Ferrero, A, Palisi, M, Filauro, M, Barberis, A, Azzinnaro, A, Fiscon, V, Vigna, S, D'Ambra, M, Pontecorvi, E, Anania, G, Bombardini, C, Galizia, G, Auricchio, A, Cardella, F, Genna, M, Gentilli, S, Herald, N, Castagnoli, G, Bartoli, A, Gianotti, L, Garancini, M, Bellanova, G, Palazzo, P, De Palma, G, Milone, M, Ferrari, G, Magistro, C, Giuliani, A, Di Natale, G, Brisinda, G, Cavallaro, G, Sammarco, G, Gallo, G, Goletti, O, Macchini, D, Greco, V, Amoroso, V, Guercioni, G, Benedetti, M, Guzzo, G, Pata, F, Scandroglio, I, Roscio, F, Jovine, E, Lombardi, R, La Rocca, F, Di Capua, F, Lanci, C, Leli, R, Borasi, A, Lepiane, P, Balla, A, Liberatore, E, Morelli, L, Di Franco, G, Lucchi, A, Vittori, L, Bonavina, L, Asti, E, Maggioni, D, Martino, G, Manca, G, Delvecchio, A, Tedesco, M, Gambardella, D, Marafioti, S, De Marco, M, Guicciardi, M, Motta, M, Calgaro, M, Adamo, V, Guerrieri, M, Coletta, P, Ortenzi, M, Martines, G, Lantone, G, Martinotti, M, Fassardi, G, Castriconi, M, Squillante, S, De Luca, M, Pavanello, M, Di Marco, C, Ronconi, M, Casiraghi, S, Mazzaferro, V, Battiston, C, Perrotta, M, Ripa, C, Giancarlo, M, Panizzo, V, Millo, P, Contul, R, Ferraro, V, Molino, C, Crolla, E, Moretto, G, Bacchion, M, Morino, M, Allaix, M, Motterlini, E, Petracca, M, Muratore, A, Musella, M, Vitiello, A, Nardo, B, Crocco, V, Navarra, G, Lazzara, S, Cuoghi, M, Olmi, S, Oldani, A, Uccelli, M, Opocher, E, Giovenzana, M, De Paolis, P, Santarelli, M, Delrio, P, Carbone, F, Bianchi, P, Formisano, G, Capelli, P, Baldini, E, Festa, P, Mottola, A, Merola, G, Perrotta, N, Celiento, M, Personnettaz, E, Muzio, S, Petitti, T, Melchiorre, A, Piccoli, M, Pecchini, F, Frontali, A, Maffioli, A, Maida, P, Tammaro, P, Pignata, G, Andreuccetti, J, Pilone, V, Renzulli, M, Pintaldi, S, Ceretti, A, Mariani, N, Pisanu, A, Polastri, R, Maiello, F, Porcu, A, Perra, T, Mucilli, F, Troisi, R, Montalti, R, Scognamillo, F, Delogu, D, Galleano, R, Malerba, M, Salfi, R, Pisano, M, Sechi, R, Cillara, N, Ramuscello, S, De Leo, E, Restini, E, Tumolo, R, Cianci, P, Capuzzolo, S, Rizzo, M, Recordare, A, Santoro, R, Amodio, P, Rocca, A, Cecere, G, Romito, R, Portigliotti, L, Rosati, R, Elmore, U, Russello, D, Latteri, S, Costarella, S, Massa, S, Capasso, L, Santangelo, M, Sodo, M, Sarro, G, Rivolta, U, Scabini, S, Pertile, D, Selvaggi, F, Rossi, S, Pellino, G, Sganga, G, Fransvea, P, Testa, S, De Rosa, C, Siquini, W, Trana, C, Solej, M, Bolzon, S, Guerra, E, Stella, M, Ferrara, F, Stipa, F, Stringhi, E, Celotti, A, Taglietti, L, Del Giudice, R, Talarico, C, Ruggiero, M, Tirone, G, Romario, U, Petz, W, Caracino, V, Rossetti, V, Verza, L, Vescovi, L, Marini, M, Vettoretto, N, Botteri, E, Vincenti, L, Giannandrea, G, Viora, T, Maganuco, L, Veronesi, P, Zani, B, Zanus, G, Brizzolari, M, Zanzi, F, Guariniello, A, Zappa, M, Galfrascoli, E, Zonta, S, Oragano, L, Zuliani, W, Chiari, D, Bracale U., Podda M., Castiglioni S., Peltrini R., Sartori A., Arezzo A., Corcione F., Agresta F., Antonucci A., Zanframundo C., Cavallo F., Mazzarolo G., Agrusa A., Di Buono G., Aldrighetti L., Fiorentini G., Lucianetti A., Magnone S., Alfieri S., Rosa F., Altomare D. F., Picciariello A., Parisi A., Di Cintio A., Amisano M. F., Cravero F., Ammendola M., Ammerata G., Anastasi A., Canonico G., Gattolin A., Travaglio E., De Palma M., Angelini P., Galante F., Benevento A., Rausei S., Serao A., Abbatini F., Annecchiarico M., Varricchio A., Annessi V., Tumiati D., Annicchiarico A., Mirabella A., Marino M. V., Spinelli A., Braun A., Santi H. T., Romano L., Antoniutti M., Armellino M. F., Argenio G., Verzelli A., Budassi A., Baiocchi G., Alfano M. S., Balani A., Barone M., Baldazzi G., Cassini D., Canger R. C. B., Zabbialini G., Belli A., Izzo F., Bertolino F., Brunetti M., Bianco F., Cappiello A., Boccia L., Boffi B., Perna F., Bonilauri S., Frazzetta G., Bordoni P., Fleres F., Borghi F., Giraudo G., Bottino V., Canfora A., Piccoli F. B., Calligaris L., Nipote B., Nasti A. G., Bufalari A., Bettarini F., Buononato M., Greco M., Calo P. G., Medas F., Cardamone E., Castaldo P., Carlini M., Spoletini D., De Nisco C., Pulighe F., Feo C. V., Fabbri N., Antropoli C., Foroni F., Carnazza M., Ragazzi S., Cassinotti E., Boni L., Catena F., Giuffrida M., Perrone G., Ccotsoglou C., Granieri S., Ceccarelli G., Bugiantella W., Cedolini C., Seriau L., Cesari M., Contine A., Chiara O., Cimbanassi S., Cocozza E., Berselli M., Fantini C., Costi R., Casali L., Morini A., Crafa F., Vanela S., Curro G., Orsini V., Da Lio C., Biral M., Danelli P., Guerci C., Scala D., Marino G., De Carlis L., Lauterio A., De Giorgi D., Sciannamea G., De Manzini N., Losurdo P., Sangiuliano N., Degiuli M., Caterina F., Del Rio P., Bonati E., Di Lernia S., Ardizzone M. V. R., Di Saverio S., Franchi C., Di Venere B., Miglio R., Cuccurullo D., Sagnelli C., Docimo L., Tolone S., Longoni M., Faillace G., Rondelli F., Pennella F. P., Colucci V., Carfora T., Muttillo I. A., Picardi B., Stefano R., Campagnacci R., Maurizi A., Tricarico F., Montagna M., Amedeo E., Scollica M. C., Lauro E., Laterza E., Molinari E., Berta G., Bono D., Fabozzi M., Romano M., Facci E., Parini D., Farfaglia R., Arizzi V., Farsi M., Miranda E., Fei L., Flavio G., Pirozzi F., Sciuto A., Ferrero A., Palisi M., Filauro M., Barberis A., Azzinnaro A., Fiscon V., Vigna S., D'ambra M., Pontecorvi E., Anania G., Bombardini C., Galizia G., Auricchio A., Cardella F., Genna M., Gentilli S., Herald N., Castagnoli G., Bartoli A., Gianotti L., Garancini M., Bellanova G., Palazzo P., De Palma G., Milone M., Ferrari G., Magistro C., Giuliani A., Di Natale G., Brisinda G., Cavallaro G., Sammarco G., Gallo G., Goletti O., Macchini D., Greco V., Amoroso V., Guercioni G., Benedetti M., Guzzo G., Pata F., Scandroglio I., Roscio F., Jovine E., Lombardi R., La Rocca F., Di Capua F., Lanci C., Leli R., Borasi A., Lepiane P., Balla A., Liberatore E., Morelli L., Di Franco G., Lucchi A., Vittori L., Bonavina L., Asti E., Maggioni D., Martino G., Manca G., Delvecchio A., Tedesco M., Gambardella D., Marafioti S., De Marco M. L., Guicciardi M. A., Motta M., Calgaro M., Adamo V., Guerrieri M., Coletta P., Ortenzi M., Martines G., Lantone G., Martinotti M., Fassardi G., Castriconi M., Squillante S., De Luca M., Pavanello M., Di Marco C., Ronconi M., Casiraghi S., Mazzaferro V., Battiston C., Perrotta M., Ripa C., Giancarlo M., Panizzo V., Millo P., Contul R. B., Ferraro V., Molino C., Crolla E., Moretto G., Bacchion M., Morino M., Allaix M. E., Motterlini E., Petracca M., Muratore A., Musella M., Vitiello A., Nardo B., Crocco V., Navarra G., Lazzara S., Navarra G. G., Cuoghi M., Olmi S., Oldani A., Uccelli M., Opocher E., Giovenzana M., De Paolis P., Santarelli M., Delrio P., Carbone F., Bianchi P. P., Formisano G., Capelli P., Baldini E., Festa P., Mottola A., Merola G., Perrotta N., Celiento M., Personnettaz E., Muzio S., Petitti T., Melchiorre A., Piccoli M., Pecchini F., Frontali A., Maffioli A., Maida P., Tammaro P., Pignata G., Andreuccetti J., Pilone V., Renzulli M., Pintaldi S., Ceretti A. P., Mariani N. M., Pisanu A., Polastri R., Maiello F., Porcu A., Perra T., Mucilli F., Troisi R., Montalti R., Scognamillo F., Delogu D., Galleano R., Malerba M., Salfi R., Pisano M., Sechi R., Cillara N., Ramuscello S., De Leo E., Restini E., Tumolo R., Cianci P., Capuzzolo S., Rizzo M., Recordare A., Santoro R., Amodio P. M., Rocca A., Cecere G., Romito R., Portigliotti L., Rosati R., Elmore U., Russello D., Latteri S., Costarella S. M., Massa S., Capasso L., Santangelo M., Sodo M., Sarro G., Rivolta U., Scabini S., Pertile D., Selvaggi F., Rossi S., Pellino G., Sganga G., Fransvea P., Testa S., De Rosa C., Siquini W., Trana C., Solej M., Bolzon S., Guerra E., Stella M., Ferrara F., Stipa F., Stringhi E., Celotti A., Taglietti L., Del Giudice R., Talarico C. A., Ruggiero M., Tirone G., Romario U. F., Petz W., Caracino V., Rossetti V., Verza L. A., Vescovi L., Marini M., Vettoretto N., Botteri E., Vincenti L., Giannandrea G., Viora T., Maganuco L., Veronesi P., Zani B., Zanus G., Brizzolari M., Zanzi F., Guariniello A., Zappa M. A., Galfrascoli E., Zonta S., Oragano L., Zuliani W., and Chiari D.

Abstract

The Collaborative Group there are two authors names are incorrect. The correct names are provided below: Paolo Pietro Bianchi and Giampaolo Formisano Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence.

Published
2021

30. Changes in surgicaL behaviOrs dUring the CoviD-19 pandemic. The SICE CLOUD19 Study

Author

Bracale, U., Podda, Maria Vittoria, Castiglioni, S., Peltrini, R., Sartori, Alessandra, Arezzo, A., Corcione, F., Agresta, F., Antonucci, A., Zanframundo, C., Cavallo, F., Mazzarolo, G., Agrusa, A., Di Buono, G., Aldrighetti, L., Fiorentini, G., Lucianetti, A., Magnone, S., Alfieri, Sergio, Rosa, Fausto, Altomare, D. F., Picciariello, A., Parisi, Carmelo Maria Antonio, Di Cintio, A., Amisano, M. F., Cravero, F., Ammendola, M., Ammerata, G., Anastasi, A., Canonico, G., Gattolin, A., Travaglio, E., De Palma, M., Angelini, P., Galante, F., Benevento, A., Rausei, S., Serao, A., Abbatini, F., Annecchiarico, M., Varricchio, A., Annessi, V., Tumiati, D., Annicchiarico, A., Mirabella, A., Marino, M. V., Spinelli, A., Braun, A., Santi, H. T., Romano, L., Antoniutti, M., Armellino, M. F., Argenio, G., Verzelli, A., Budassi, A., Baiocchi, G., Alfano, M. S., Balani, A., Barone, M., Baldazzi, G., Cassini, D., Canger, R. C. B., Zabbialini, G., Belli, Andrea, Izzo, Filippo, Bertolino, F., Brunetti, Maria Mercede, Bianco, Flaviana, Cappiello, A., Boccia, L., Boffi, B., Perna, Francesco, Bonilauri, S., Frazzetta, G., Bordoni, P., Fleres, F., Borghi, F., Giraudo, G., Bottino, V., Canfora, A., Piccoli, F. B., Calligaris, L., Nipote, B., Nasti, A. G., Bufalari, A., Bettarini, F., Buononato, M., Greco, M., Calo, P. G., Medas, F., Cardamone, E., Castaldo, P., Carlini, M., Spoletini, D., De Nisco, C., Pulighe, F., Feo, C. V., Fabbri, N., Antropoli, C., Foroni, F., Carnazza, M., Ragazzi, S., Cassinotti, E., Boni, L., Catena, F., Giuffrida, M., Perrone, Giuseppe, Ccotsoglou, C., Granieri, S., Ceccarelli, G., Bugiantella, W., Cedolini, C., Seriau, L., Cesari, Matteo, Contine, A., Chiara, Osvaldo, Cimbanassi, S., Cocozza, E., Berselli, M., Fantini, C., Costi, R., Casali, L., Morini, A., Crafa, F., Vanela, S., Curro, G., Orsini, V., Da Lio, C., Biral, Maria Francesca, Danelli, P., Guerci, C., Scala, D., Marino, Giuseppe, De Carlis, L., Lauterio, A., De Giorgi, D., Sciannamea, G., De Manzini, N., Losurdo, P., Sangiuliano, N., Degiuli, M., Caterina, F., Del Rio, P., Bonati, E., Di Lernia, S., Ardizzone, M. V. R., Di Saverio, S., Franchi, C., Di Venere, B., Miglio, R., Cuccurullo, D., Sagnelli, C., Docimo, L., Tolone, S., Longoni, M., Faillace, G., Rondelli, F., Pennella, F. P., Colucci, V., Carfora, T., Muttillo, I. A., Picardi, B., Stefano, R., Campagnacci, R., Maurizi, A., Tricarico, F., Montagna, M., Amedeo, E., Scollica, M. C., Lauro, E., Laterza, E., Molinari, E., Berta, G., Bono, D., Fabozzi, Simone Michele, Romano, M., Facci, E., Parini, D., Farfaglia, R., Arizzi, V., Farsi, M., Miranda, E., Fei, L., Flavio, G., Pirozzi, F., Sciuto, A., Ferrero, A., Palisi, M., Filauro, M., Barberis, A., Azzinnaro, A., Fiscon, V., Vigna, S., D'Ambra, M., Pontecorvi, E., Anania, G., Bombardini, C., Galizia, G., Auricchio, Anna Maria, Cardella, F., Genna, M., Gentilli, S., Herald, N., Castagnoli, G., Bartoli, A., Gianotti, L., Garancini, M., Bellanova, G., Palazzo, P., De Palma, G., Milone, Maria, Ferrari, G., Magistro, C., Giuliani, Antonio, Di Natale, Maria Grazia, Brisinda, Giuseppe, Cavallaro, G., Sammarco, G., Gallo, Giuseppe, Goletti, O., Macchini, D., Greco, Viviana, Amoroso, V., Guercioni, G., Benedetti, M., Guzzo, G., Pata, F., Scandroglio, I., Roscio, F., Jovine, E., Lombardi, Roberto, La Rocca, F., Di Capua, F., Lanci, C., Leli, R., Borasi, A., Lepiane, P., Balla, A., Liberatore, E., Morelli, L., Di Franco, G., Lucchi, A., Vittori, L., Bonavina, L., Asti, Emilio Fabrizio, Maggioni, D., Martino, G., Manca, Gavina, Delvecchio, A., Tedesco, M., Gambardella, D., Marafioti, S., De Marco, M. L., Guicciardi, M. A., Motta, M., Calgaro, M., Adamo, V., Guerrieri, Maria Chiara, Coletta, P., Ortenzi, M., Martines, G., Lantone, G., Martinotti, M., Fassardi, G., Castriconi, M., Squillante, S., De Luca, M., Pavanello, M., Di Marco, C., Ronconi, M., Casiraghi, Maria Stella, Mazzaferro, V., Battiston, C., Perrotta, M., Ripa, C., Giancarlo, M., Panizzo, V., Millo, P., Contul, R. B., Ferraro, V., Molino, C., Crolla, E., Moretto, G., Bacchion, M., Morino, M., Allaix, M. E., Motterlini, E., Petracca, Martina, Muratore, A., Musella, Martina, Vitiello, A., Nardo, B., Crocco, V., Navarra, G., Lazzara, S., Navarra, G. G., Cuoghi, M., Olmi, S., Oldani, Alberto, Uccelli, M., Opocher, E., Giovenzana, M., De Paolis, P., Santarelli, M., Delrio, P., Carbone, F., Bianchi, P. P. G., Formisano, Capelli, P., Baldini, E., Festa, P., Mottola, Armando, Merola, G., Perrotta, N., Celiento, M., Personnettaz, E., Muzio, S., Petitti, T., Melchiorre, A., Piccoli, M., Pecchini, F., Frontali, A., Maffioli, A., Maida, P., Tammaro, P., Pignata, G., Andreuccetti, J., Pilone, V., Renzulli, M., Pintaldi, S., Ceretti, A. P., Mariani, N. M., Pisanu, A., Polastri, R., Maiello, F., Porcu, A., Perra, T., Mucilli, F., Troisi, R., Montalti, R., Scognamillo, F., Delogu, D., Galleano, R., Malerba, M., Salfi, R., Pisano, M., Sechi, R., Cillara, N., Ramuscello, S., De Leo, E., Restini, E., Tumolo, R., Cianci, P., Capuzzolo, S., Rizzo, M., Recordare, A., Santoro, Roberto, Amodio, P. M., Rocca, A., Cecere, G., Romito, R., Portigliotti, L., Rosati, R., Elmore, U., Russello, D., Latteri, S., Costarella, S. M., Massa, S., Capasso, L., Santangelo, M., Sodo, M., Sarro, G., Rivolta, U., Scabini, S., Pertile, D., Selvaggi, F., Rossi, S., Pellino, G., Sganga, Gabriele, Fransvea, P., Testa, S., De Rosa, Maria Cristina, Siquini, W., Trana, C., Solej, M., Bolzon, S., Guerra, Eliana, Stella, M., Ferrara, F., Stipa, F., Stringhi, E., Celotti, A., Taglietti, L., Del Giudice, R., Talarico, C. A., Ruggiero, Miriam, Tirone, G., Romario, U. F., Petz, W., Caracino, V., Rossetti, V., Verza, L. A., Vescovi, L., Marini, M., Vettoretto, N., Botteri, E., Vincenti, L., Giannandrea, G., Viora, T., Maganuco, L., Veronesi, P., Zani, B., Zanus, G., Brizzolari, M., Zanzi, F., Guariniello, A., Zappa, M. A., Galfrascoli, E., Zonta, S., Oragano, L., Zuliani, W., Chiari, D., Bracale, Umberto, Podda, Mauro, Castiglioni, Simone, Peltrini, Roberto, Sartori, Alberto, Arezzo, Alberto, Corcione, Francesco, Agresta, Ferdinando, Rosati, Riccardo, Umberto, Bracale, Mauro, Podda, Simone, Castiglioni, Roberto, Peltrini, Alberto, Sartori, Alberto, Arezzo, Francesco, Corcione, Ferdinando, Agresta, CLOUD-19 Collaborative Group Adelmo Antonucci, Claudia, Zanframundo, Fabio, Cavallo, Giorgio, Mazzarolo, Antonio, Agrusa, Giuseppe Di Buono, Luca, Aldrighetti, Guido, Fiorentini, Alessandro, Lucianetti, Stefano, Magnone, Sergio, Alfieri, Fausto, Rosa, Altomare, Donato F., Arcangelo, Picciariello, Amilcare, Parisi, Antonio Di Cintio, Marco Francesco Amisano, Francesca, Cravero, Michele, Ammendola, Giorgio, Ammerata, Alessandro, Anastasi, Giuseppe, Canonico, Andra, Gattolin, Elisabetta, Travaglio, Andrea, Sartori, Massimiliano De Palma, Pierluigi, Angelini, Francesco, Galante, Angelo, Benevento, Stefano, Rausei, Angelo, Serao, Francesca, Abbatini, Mario, Annecchiarico, Antonio, Varricchio, Valerio, Annessi, David, Tumiati, Alfredo, Annicchiarico, Antonello, Mirabella, Marino, Marco V., Antonino, Spinelli, Antonio, Braun, Hong Tham Santi, Lucia, Romano, Michele, Antoniutti, Mariano Fortunato Armellino, Giulio, Argenio, Augusto, Verzelli, Andrea, Budassi, Gianluca, Baiocchi, Marie Sophie Alfano, Alessandro, Balani, Marco, Barone, Gianandrea, Baldazzi, Diletta, Cassini, Ruben Carlo Balzarotti Canger, Gianpietro, Zabbialini, Andrea, Belli, Francesco, Izzo, Franco, Bertolino, Marco, Brunetti, Francesco, Bianco, Antonio, Cappiello, Luigi, Boccia, Bernardo, Boffi, Federico, Perna, Stefano, Bonilauri, Giuseppe, Frazzetta, Pierpaolo, Bordoni, Francesco, Flere, Felice, Borghi, Giorgio, Giraudo, Vincenzo, Bottino, Alfonso, Canfora, Fabrizio Briganti Piccoli, Luca, Calligari, Bruno, Nipote, Aniello Gennaro Nasti, Andrea, Bufalari, Francesca, Bettarini, Massimo, Buononato, Marco, Greco, Pietro Giorgio Calò, Fabio, Meda, Eugenia, Cardamone, Pasquale, Castaldo, Massimo, Carlini, Domenico, Spoletini, Carlo De Nisco, Fabio, Pulighe, Feo, Carlo V., Nicolò, Fabbri, Carmine, Antropoli, Fabrizio, Foroni, Maurizio, Carnazza, Salvatore, Ragazzi, Elisa, Cassinotti, Luigi, Boni, Fausto, Catena, Mario, Giuffrida, Gennaro, Perrone, Christian, Ccotsoglou, Stefano, Granieri, Graziano, Ceccarelli, Walter, Bugiantella, Carla, Cedolini, Luca, Seriau, Maurizio, Cesari, Alessandro, Contine, Osvaldo, Chiara, Stefania, Cimbanassi, Eugenio, Cocozza, Mattia, Berselli, Corrado, Fantini, Renato, Costi, Lorenzo, Casali, Andrea, Morini, Francesco, Crafa, Serafino, Vanela, Giuseppe, Currò, Vincenzo, Orsini, Corrado Da Lio, Mario, Biral, Piergiorgio, Danelli, Claudio, Guerci, Dario, Scala, Graziella, Marino, Luciano De Carlis, Andrea, Lauterio, Donato De Giorgi, Gianluca, Sciannamea, Nicolo De Manzini, Pasquale, Losurdo, Maurizio De Palma, Nicola, Sangiuliano, Maurizio, Degiuli, Franco, Caterina, Paolo Del Rio, Elena, Bonati, Stefano Di Lernia, Marco Vittorio Rossi Ardizzone, Salomone Di Saverio, Caterina, Franchi, Beatrice Di Venere, Rosanna, Miglio, Diego, Cuccurullo, Carlo, Sagnelli, Docimo, Ludovico, Tolone, Salvatore, Mauro, Longoni, Giuseppe, Faillace, Fabio, Rondelli, Francesca Pennetti Pennella, Vincenzo, Colucci, Teresa, Carfora, Irnerio Angelo Muttillo, Biagio, Picardi, Rossi, Stefano, Roberto, Campagnacci, Angela, Maurizi, Fausto, Tricarico, Marco, Montagna, Elio, Amedeo, Scollica, Michela C., Enrico, Lauro, Ernesto, Laterza, Enrico, Molinari, Berta, G., Dario, Bono, Massimiliano, Fabozzi, Mafalda, Romano, Enzo, Facci, Dario, Parini, Roberto, Farfaglia, Valeria, Arizzi, Marco, Farsi, Egidio, Miranda, Fei, Landino, Giordano, Flavio, Felice, Pirozzi, Antonio, Sciuto, Alessandro, Ferrero, Marco, Palisi, Marco, Filauro, Andrea, Barberi, Antonio, Azzinnaro, Valentino, Fiscon, Silvia, Vigna, Michele, D’Ambra, Emanuele, Pontecorvi, Gabriele, Anania, Cristina, Bombardini, Galizia, Gennaro, Auricchio, Annamaria, Cardella, Francesca, Michele, Genna, Sergio, Gentilli, Nikaj, Herald, Giampaolo, Castagnoli, Alberto, Bartoli, Luca, Gianotti, Mattia, Garancini, Giovanni, Bellanova, Paola, Palazzo, Giovanni De Palma, Marco, Milone, Giovanni, Ferrari, Carmelo, Magistro, Antonio, Giuliani, Giuseppe Di Natale, Giuseppe, Brisinda, Giuseppe, Cavallaro, Giuseppe, Sammarco, Gaetano, Gallo, Orlando, Goletti, Daniele, Macchini, Vincenzo, Greco, Vincenzo, Amoroso, Gianluca, Guercioni, Michele, Benedetti, Guglielmo, Guzzo, Francesco, Pata, Ildo, Scandroglio, Francesco, Roscio, Elio, Jovine, Raffaele, Lombardi, Francesco La Rocca, Francesca Di Capua, Carmine, Lanci, Renzo, Leli, Andrea, Borasi, Pasquale, Lepiane, Andrea, Balla, Edoardo, Liberatore, Luca, Morelli, Gregorio Di Franco, Andrea, Lucchi, Laura, Vittori, Luigi, Bonavina, Emanuele, Asti, Dario, Maggioni, Gerosa, Martino, Giuseppe, Manca, Antonella, Delvecchio, Manfredo, Tedesco, Denise, Gambardella, Salvatore, Marafioti, Maria Luisa De Marco, Marco Azzola Guicciardi, Massimo, Motta, Marco, Calgaro, Vincenzo, Adamo, Mario, Guerrieri, Pietro, Coletta, Monica, Ortenzi, Gennaro, Martine, Giuliano, Lantone, Mario, Martinotti, Giuseppe, Fassardi, Maurizio, Castriconi, Simone, Squillante, Maurizio De Luca, Maurizio, Pavanello, Carlo Di Marco, Maurizio, Ronconi, Silvia, Casiraghi, Vincenzo, Mazzaferro, Carlo, Battiston, Michele, Perrotta, Carmine, Ripa, Micheletto, Giancarlo, Valerio, Panizzo, Paolo, Millo, Riccardo Brachet Contul, Valentina, Ferraro, Carlo, Molino, Enrico, Crolla, Gianluigi, Moretto, Matilde, Bacchion, Mario, Morino, Marco Ettore Allaix, Enrico, Motterlini, Michele, Petracca, Andrea, Muratore, Mario, Musella, Antonio, Vitiello, Bruno, Nardo, Veronica, Crocco, Giuseppe, Navarra, Salvatore, Lazzara, Giuseppe Giovanni Navarra, Manuela, Cuoghi, Stefano, Olmi, Alberto, Oldani, Matteo, Uccelli, Enrico, Opocher, Marco, Giovenzana, Paolo De Paolis, Mauro, Santarelli, Paolo, Delrio, Fabio, Carbone, Paolo Pietro Giampaolo Bianchi, Formisano, Patrizio, Capelli, Edoardo, Baldini, Patrizio, Festa, Arianna, Mottola, Giovanni, Merola, Nicola, Perrotta, Marta, Celiento, Eraldo, Personnettaz, Stefania, Muzio, Tommaso, Petitti, Antonietta, Melchiorre, Micaela, Piccoli, Francesca, Pecchini, Alice, Frontali, Anna, Maffioli, Pietro, Maida, Pasquale, Tammaro, Giusto, Pignata, Jacopo, Andreuccetti, Vincenzo, Pilone, Michele, Renzulli, Salvatore, Pintaldi, Andrea Pisani Ceretti, Nicolò Maria Mariani, Adolfo, Pisanu, Roberto, Polastri, Fabio, Maiello, Alberto, Porcu, Teresa, Perra, Felice, Mucilli, Mirko, Barone, Roberto, Troisi, Roberto, Montalti, Fabrizio, Scognamillo, Daniele, Delogu, Raffaele, Galleano, Michele, Malerba, Raffaele, Salfi, Marcello, Pisano, Raffaele, Sechi, Nicola, Cillara, Salvatore, Ramuscello, Eugenio De Leo, Enrico, Restini, Rocco, Tumolo, Pasquale, Cianci, Sabino, Capuzzolo, Maurizio, Rizzo, Alfonso, Recordare, Roberto, Santoro, Pietro Maria Amodio, Aldo, Rocca, Giuseppe, Cecere, Raffaele, Romito, Luca, Portigliotti, Riccardo, Rosati, Ugo, Elmore, Domenico, Russello, Saverio, Latteri, Salvatore Maria Costarella, Salvatore, Massa, Lorenzo, Capasso, Michele, Santangelo, Maurizio, Sodo, Giuliano, Sarro, Umberto, Rivolta, Stefano, Scabini, Davide, Pertile, Federico, Selvaggi, Selene, Rossi, Selvaggi, Francesco, Pellino, Gianluca, Gabriele, Sganga, Pietro, Fransvea, Silvio, Testa, Clemente De Rosa, Walter, Siquini, Cristian, Tranà, Mario, Solej, Stefano, Bolzon, Enrico, Guerra, Marco, Stella, Francesco, Ferrara, Francesco, Stipa, Enrico, Stringhi, Andrea, Celotti, Lucio, Taglietti, Roberto Del Giudice, Carlo Alessandro Talarico, Michele, Ruggiero, Giuseppe, Tirone, Uberto Fumagalli Romario, Wanda, Petz, Valerio, Caracino, Valentina, Rossetti, Luca Andrea Verza, Lorenzo, Vescovi, Michele, Marini, Nereo, Vettoretto, Emanuele, Botteri, Leonardo, Vincenti, Giusy, Giannandrea, Tiziana, Viora, Lorenzo, Maganuco, Paolo, Veronesi, Bruno, Zani, Giacomo, Zanu, Marco, Brizzolari, Federico, Zanzi, Anna, Guariniello, Marco Antonio Zappa, Elisa, Galfrascoli, Sandro, Zonta, Luigi, Oragano, Walter Zuliani &amp, Damiano, Chiari, de Manzini, Nicolo', Agresta, Ferdinando, Agrusa, Antonino, Di Buono, Giuseppe, Bracale, U., Podda, M., Castiglioni, S., Peltrini, R., Sartori, A., Arezzo, A., Corcione, F., Agresta, F., Antonucci, A., Zanframundo, C., Cavallo, F., Mazzarolo, G., Agrusa, A., Di Buono, G., Aldrighetti, L., Fiorentini, G., Lucianetti, A., Magnone, S., Alfieri, S., Rosa, F., Altomare, D. F., Picciariello, A., Parisi, A., Di Cintio, A., Amisano, M. F., Cravero, F., Ammendola, M., Ammerata, G., Anastasi, A., Canonico, G., Gattolin, A., Travaglio, E., De Palma, M., Angelini, P., Galante, F., Benevento, A., Rausei, S., Serao, A., Abbatini, F., Annecchiarico, M., Varricchio, A., Annessi, V., Tumiati, D., Annicchiarico, A., Mirabella, A., Marino, M. V., Spinelli, A., Braun, A., Santi, H. T., Romano, L., Antoniutti, M., Armellino, M. F., Argenio, G., Verzelli, A., Budassi, A., Baiocchi, G., Alfano, M. S., Balani, A., Barone, M., Baldazzi, G., Cassini, D., Canger, R. C. B., Zabbialini, G., Belli, A., Izzo, F., Bertolino, F., Brunetti, M., Bianco, F., Cappiello, A., Boccia, L., Boffi, B., Perna, F., Bonilauri, S., Frazzetta, G., Bordoni, P., Fleres, F., Borghi, F., Giraudo, G., Bottino, V., Canfora, A., Piccoli, F. B., Calligaris, L., Nipote, B., Nasti, A. G., Bufalari, A., Bettarini, F., Buononato, M., Greco, M., Calo, P. G., Medas, F., Cardamone, E., Castaldo, P., Carlini, M., Spoletini, D., De Nisco, C., Pulighe, F., Feo, C. V., Fabbri, N., Antropoli, C., Foroni, F., Carnazza, M., Ragazzi, S., Cassinotti, E., Boni, L., Catena, F., Giuffrida, M., Perrone, G., Ccotsoglou, C., Granieri, S., Ceccarelli, G., Bugiantella, W., Cedolini, C., Seriau, L., Cesari, M., Contine, A., Chiara, O., Cimbanassi, S., Cocozza, E., Berselli, M., Fantini, C., Costi, R., Casali, L., Morini, A., Crafa, F., Vanela, S., Curro, G., Orsini, V., Da Lio, C., Biral, M., Danelli, P., Guerci, C., Scala, D., Marino, G., De Carlis, L., Lauterio, A., De Giorgi, D., Sciannamea, G., De Manzini, N., Losurdo, P., Sangiuliano, N., Degiuli, M., Caterina, F., Del Rio, P., Bonati, E., Di Lernia, S., Ardizzone, M. V. R., Di Saverio, S., Franchi, C., Di Venere, B., Miglio, R., Cuccurullo, D., Sagnelli, C., Docimo, L., Tolone, S., Longoni, M., Faillace, G., Rondelli, F., Pennella, F. P., Colucci, V., Carfora, T., Muttillo, I. A., Picardi, B., Stefano, R., Campagnacci, R., Maurizi, A., Tricarico, F., Montagna, M., Amedeo, E., Scollica, M. C., Lauro, E., Laterza, E., Molinari, E., Bono, D., Fabozzi, M., Romano, M., Facci, E., Parini, D., Farfaglia, R., Arizzi, V., Farsi, M., Miranda, E., Fei, L., Flavio, G., Pirozzi, F., Sciuto, A., Ferrero, A., Palisi, M., Filauro, M., Barberis, A., Azzinnaro, A., Fiscon, V., Vigna, S., D'Ambra, M., Pontecorvi, E., Anania, G., Bombardini, C., Galizia, G., Auricchio, A., Cardella, F., Genna, M., Gentilli, S., Herald, N., Castagnoli, G., Bartoli, A., Gianotti, L., Garancini, M., Bellanova, G., Palazzo, P., De Palma, G., Milone, M., Ferrari, G., Magistro, C., Giuliani, A., Di Natale, G., Brisinda, G., Cavallaro, G., Sammarco, G., Gallo, G., Goletti, O., Macchini, D., Greco, V., Amoroso, V., Guercioni, G., Benedetti, M., Guzzo, G., Pata, F., Scandroglio, I., Roscio, F., Jovine, E., Lombardi, R., La Rocca, F., Di Capua, F., Lanci, C., Leli, R., Borasi, A., Lepiane, P., Balla, A., Liberatore, E., Morelli, L., Di Franco, G., Lucchi, A., Vittori, L., Bonavina, L., Asti, E., Maggioni, D., Martino, G., Manca, G., Delvecchio, A., Tedesco, M., Gambardella, D., Marafioti, S., De Marco, M. L., Guicciardi, M. A., Motta, M., Calgaro, M., Adamo, V., Guerrieri, M., Coletta, P., Ortenzi, M., Martines, G., Lantone, G., Martinotti, M., Fassardi, G., Castriconi, M., Squillante, S., De Luca, M., Pavanello, M., Di Marco, C., Ronconi, M., Casiraghi, S., Mazzaferro, V., Battiston, C., Perrotta, M., Ripa, C., Giancarlo, M., Panizzo, V., Millo, P., Contul, R. B., Ferraro, V., Molino, C., Crolla, E., Moretto, G., Bacchion, M., Morino, M., Allaix, M. E., Motterlini, E., Petracca, M., Muratore, A., Musella, M., Vitiello, A., Nardo, B., Crocco, V., Navarra, G., Lazzara, S., Navarra, G. G., Cuoghi, M., Olmi, S., Oldani, A., Uccelli, M., Opocher, E., Giovenzana, M., De Paolis, P., Santarelli, M., Delrio, P., Carbone, F., Bianchi, P. P. G., Capelli, P., Baldini, E., Festa, P., Mottola, A., Merola, G., Perrotta, N., Celiento, M., Personnettaz, E., Muzio, S., Petitti, T., Melchiorre, A., Piccoli, M., Pecchini, F., Frontali, A., Maffioli, A., Maida, P., Tammaro, P., Pignata, G., Andreuccetti, J., Pilone, V., Renzulli, M., Pintaldi, S., Ceretti, A. P., Mariani, N. M., Pisanu, A., Polastri, R., Maiello, F., Porcu, A., Perra, T., Mucilli, F., Troisi, R., Montalti, R., Scognamillo, F., Delogu, D., Galleano, R., Malerba, M., Salfi, R., Pisano, M., Sechi, R., Cillara, N., Ramuscello, S., De Leo, E., Restini, E., Tumolo, R., Cianci, P., Capuzzolo, S., Rizzo, M., Recordare, A., Santoro, R., Amodio, P. M., Rocca, A., Cecere, G., Romito, R., Portigliotti, L., Rosati, R., Elmore, U., Russello, D., Latteri, S., Costarella, S. M., Massa, S., Capasso, L., Santangelo, M., Sodo, M., Sarro, G., Rivolta, U., Scabini, S., Pertile, D., Selvaggi, F., Rossi, S., Pellino, G., Sganga, G., Fransvea, P., Testa, S., De Rosa, C., Siquini, W., Trana, C., Solej, M., Bolzon, S., Guerra, E., Stella, M., Ferrara, F., Stipa, F., Stringhi, E., Celotti, A., Taglietti, L., Del Giudice, R., Talarico, C. A., Ruggiero, M., Tirone, G., Romario, U. F., Petz, W., Caracino, V., Rossetti, V., Verza, L. A., Vescovi, L., Marini, M., Vettoretto, N., Botteri, E., Vincenti, L., Giannandrea, G., Viora, T., Maganuco, L., Veronesi, P., Zani, B., Zanus, G., Brizzolari, M., Zanzi, F., Guariniello, A., Zappa, M. A., Galfrascoli, E., Zonta, S., Oragano, L., Zuliani, W., Chiari, D., Bracale, U, Podda, M, Castiglioni, S, Peltrini, R, Sartori, A, Arezzo, A, Corcione, F, Agresta, F, Antonucci, A, Zanframundo, C, Cavallo, F, Mazzarolo, G, Agrusa, A, Di Buono, G, Aldrighetti, L, Fiorentini, G, Lucianetti, A, Magnone, S, Alfieri, S, Rosa, F, Altomare, D, Picciariello, A, Parisi, A, Di Cintio, A, Amisano, M, Cravero, F, Ammendola, M, Ammerata, G, Anastasi, A, Canonico, G, Gattolin, A, Travaglio, E, De Palma, M, Angelini, P, Galante, F, Benevento, A, Rausei, S, Serao, A, Abbatini, F, Annecchiarico, M, Varricchio, A, Annessi, V, Tumiati, D, Annicchiarico, A, Mirabella, A, Marino, M, Spinelli, A, Braun, A, Santi, H, Romano, L, Antoniutti, M, Armellino, M, Argenio, G, Verzelli, A, Budassi, A, Baiocchi, G, Alfano, M, Balani, A, Barone, M, Baldazzi, G, Cassini, D, Canger, R, Zabbialini, G, Belli, A, Izzo, F, Bertolino, F, Brunetti, M, Bianco, F, Cappiello, A, Boccia, L, Boffi, B, Perna, F, Bonilauri, S, Frazzetta, G, Bordoni, P, Fleres, F, Borghi, F, Giraudo, G, Bottino, V, Canfora, A, Piccoli, F, Calligaris, L, Nipote, B, Nasti, A, Bufalari, A, Bettarini, F, Buononato, M, Greco, M, Calo, P, Medas, F, Cardamone, E, Castaldo, P, Carlini, M, Spoletini, D, De Nisco, C, Pulighe, F, Feo, C, Fabbri, N, Antropoli, C, Foroni, F, Carnazza, M, Ragazzi, S, Cassinotti, E, Boni, L, Catena, F, Giuffrida, M, Perrone, G, Ccotsoglou, C, Granieri, S, Ceccarelli, G, Bugiantella, W, Cedolini, C, Seriau, L, Cesari, M, Contine, A, Chiara, O, Cimbanassi, S, Cocozza, E, Berselli, M, Fantini, C, Costi, R, Casali, L, Morini, A, Crafa, F, Vanela, S, Curro, G, Orsini, V, Da Lio, C, Biral, M, Danelli, P, Guerci, C, Scala, D, Marino, G, De Carlis, L, Lauterio, A, De Giorgi, D, Sciannamea, G, De Manzini, N, Losurdo, P, Sangiuliano, N, Degiuli, M, Caterina, F, Del Rio, P, Bonati, E, Di Lernia, S, Ardizzone, M, Di Saverio, S, Franchi, C, Di Venere, B, Miglio, R, Cuccurullo, D, Sagnelli, C, Docimo, L, Tolone, S, Longoni, M, Faillace, G, Rondelli, F, Pennella, F, Colucci, V, Carfora, T, Muttillo, I, Picardi, B, Stefano, R, Campagnacci, R, Maurizi, A, Tricarico, F, Montagna, M, Amedeo, E, Scollica, M, Lauro, E, Laterza, E, Molinari, E, Berta, G, Bono, D, Fabozzi, M, Romano, M, Facci, E, Parini, D, Farfaglia, R, Arizzi, V, Farsi, M, Miranda, E, Fei, L, Flavio, G, Pirozzi, F, Sciuto, A, Ferrero, A, Palisi, M, Filauro, M, Barberis, A, Azzinnaro, A, Fiscon, V, Vigna, S, D'Ambra, M, Pontecorvi, E, Anania, G, Bombardini, C, Galizia, G, Auricchio, A, Cardella, F, Genna, M, Gentilli, S, Herald, N, Castagnoli, G, Bartoli, A, Gianotti, L, Garancini, M, Bellanova, G, Palazzo, P, De Palma, G, Milone, M, Ferrari, G, Magistro, C, Giuliani, A, Di Natale, G, Brisinda, G, Cavallaro, G, Sammarco, G, Gallo, G, Goletti, O, Macchini, D, Greco, V, Amoroso, V, Guercioni, G, Benedetti, M, Guzzo, G, Pata, F, Scandroglio, I, Roscio, F, Jovine, E, Lombardi, R, La Rocca, F, Di Capua, F, Lanci, C, Leli, R, Borasi, A, Lepiane, P, Balla, A, Liberatore, E, Morelli, L, Di Franco, G, Lucchi, A, Vittori, L, Bonavina, L, Asti, E, Maggioni, D, Martino, G, Manca, G, Delvecchio, A, Tedesco, M, Gambardella, D, Marafioti, S, De Marco, M, Guicciardi, M, Motta, M, Calgaro, M, Adamo, V, Guerrieri, M, Coletta, P, Ortenzi, M, Martines, G, Lantone, G, Martinotti, M, Fassardi, G, Castriconi, M, Squillante, S, De Luca, M, Pavanello, M, Di Marco, C, Ronconi, M, Casiraghi, S, Mazzaferro, V, Battiston, C, Perrotta, M, Ripa, C, Giancarlo, M, Panizzo, V, Millo, P, Contul, R, Ferraro, V, Molino, C, Crolla, E, Moretto, G, Bacchion, M, Morino, M, Allaix, M, Motterlini, E, Petracca, M, Muratore, A, Musella, M, Vitiello, A, Nardo, B, Crocco, V, Navarra, G, Lazzara, S, Cuoghi, M, Olmi, S, Oldani, A, Uccelli, M, Opocher, E, Giovenzana, M, De Paolis, P, Santarelli, M, Delrio, P, Carbone, F, Bianchi, P, Capelli, P, Baldini, E, Festa, P, Mottola, A, Merola, G, Perrotta, N, Celiento, M, Personnettaz, E, Muzio, S, Petitti, T, Melchiorre, A, Piccoli, M, Pecchini, F, Frontali, A, Maffioli, A, Maida, P, Tammaro, P, Pignata, G, Andreuccetti, J, Pilone, V, Renzulli, M, Pintaldi, S, Ceretti, A, Mariani, N, Pisanu, A, Polastri, R, Maiello, F, Porcu, A, Perra, T, Mucilli, F, Troisi, R, Montalti, R, Scognamillo, F, Delogu, D, Galleano, R, Malerba, M, Salfi, R, Pisano, M, Sechi, R, Cillara, N, Ramuscello, S, De Leo, E, Restini, E, Tumolo, R, Cianci, P, Capuzzolo, S, Rizzo, M, Recordare, A, Santoro, R, Amodio, P, Rocca, A, Cecere, G, Romito, R, Portigliotti, L, Rosati, R, Elmore, U, Russello, D, Latteri, S, Costarella, S, Massa, S, Capasso, L, Santangelo, M, Sodo, M, Sarro, G, Rivolta, U, Scabini, S, Pertile, D, Selvaggi, F, Rossi, S, Pellino, G, Sganga, G, Fransvea, P, Testa, S, De Rosa, C, Siquini, W, Trana, C, Solej, M, Bolzon, S, Guerra, E, Stella, M, Ferrara, F, Stipa, F, Stringhi, E, Celotti, A, Taglietti, L, Del Giudice, R, Talarico, C, Ruggiero, M, Tirone, G, Romario, U, Petz, W, Caracino, V, Rossetti, V, Verza, L, Vescovi, L, Marini, M, Vettoretto, N, Botteri, E, Vincenti, L, Giannandrea, G, Viora, T, Maganuco, L, Veronesi, P, Zani, B, Zanus, G, Brizzolari, M, Zanzi, F, Guariniello, A, Zappa, M, Galfrascoli, E, Zonta, S, Oragano, L, Zuliani, W, and Chiari, D

Subjects
Laparoscopic surgery, Settore MED/18 - CHIRURGIA GENERALE, medicine.medical_treatment, laparoscopy, COVID-19, Elective surgery, Emergency surgery, Survey, Oral Health, cross infection (MeSH), Surveys and Questionnaires, Epidemiology, Pandemic, Infection control, Practice Patterns, Physicians', emergency surgery, Laparoscopy, humans, medicine.diagnostic_test, General Commentary, laparoscopic surgery, infection control, Italy, physicians', Original Article, Elective Surgical Procedure, Human, heating ventilation air conditioning, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), fallow period, elective surgical procedures, pandemics, NO, aerosol generating procedures, elective surgery, survey, practice patterns, physicians', SARS-CoV-2, surveys and questionnaires, medicine, Infection Control, business.industry, General surgery, practice patterns, Surgery, business
Abstract

Background The spread of the SARS-CoV2 virus, which causes COVID-19 disease, profoundly impacted the surgical community. Recommendations have been published to manage patients needing surgery during the COVID-19 pandemic. This survey, under the aegis of the Italian Society of Endoscopic Surgery, aims to analyze how Italian surgeons have changed their practice during the pandemic. Methods The authors designed an online survey that was circulated for completion to the Italian departments of general surgery registered in the Italian Ministry of Health database in December 2020. Questions were divided into three sections: hospital organization, screening policies, and safety profile of the surgical operation. The investigation periods were divided into the Italian pandemic phases I (March–May 2020), II (June–September 2020), and III (October–December 2020). Results Of 447 invited departments, 226 answered the survey. Most hospitals were treating both COVID-19-positive and -negative patients. The reduction in effective beds dedicated to surgical activity was significant, affecting 59% of the responding units. 12.4% of the respondents in phase I, 2.6% in phase II, and 7.7% in phase III reported that their surgical unit had been closed. 51.4%, 23.5%, and 47.8% of the respondents had at least one colleague reassigned to non-surgical COVID-19 activities during the three phases. There has been a reduction in elective (> 200 procedures: 2.1%, 20.6% and 9.9% in the three phases, respectively) and emergency ( Conclusion This survey offers three faithful snapshots of how the surgical community has reacted to the COVID-19 pandemic during its three phases. The significant reduction in surgical activity indicates that better health policies and more evidence-based guidelines are needed to make up for lost time and surgery not performed during the pandemic.

Published
2021

31. Comparison between the effects of epidural lidocaine, tramadol, and lidocaine–tramadol on postoperative pain in cats undergoing elective orchiectomy.

Author

Vullo, Cecilia, Falcone, Annastella, Marino, Gabriele, Monti, Salvatore, Tambella, Adolfo Maria, Bufalari, Antonello, and Catone, Giuseppe

Subjects
POSTOPERATIVE pain, CASTRATION, TRAMADOL, LIDOCAINE, CATS, DEEP brain stimulation
Abstract

Background: In veterinary clinical practice, orchiectomy is one of the most common surgical procedures for cats and is performed mainly in young animals. The purpose of this study was to compare three different epidural (EP) analgesic protocols used in cats undergoing orchiectomy in order to determine which protocol resulted in superior outcomes in terms of perioperative analgesia. Twenty-one client-owned male cats were premedicated with a combination of dexmedetomidine (10 µg/kg) and midazolam (0.2 mg/kg) injected intramuscularly. Anesthesia was induced intravenously with propofol. Cats were randomly divided in three treatment groups of seven animals each: Group L received EP lidocaine (2 mg/kg), Group T received EP tramadol (1 mg/kg), and Group LT received EP lidocaine (2 mg/kg) plus tramadol (1 mg/kg). The post-operative pain level was assessed using two different scales: the Glasgow Composite Measure Pain Scale-Feline (CMPS-F) and the Feline Grimace Scale (FGS). Rescue analgesia was administered when the CMPS-F total score was ≥5 or the FGS total score was ≥4. Results: No adverse effects related to tramadol or lidocaine were observed. Based on post-operative pain assessments, significant differences between groups were observed according to both pain scoring systems. In particular, in Group LT, the CMPS-F and FGS scores decreased significantly in the first six hours following castration. Conclusions: Based on our results, EP lidocaine plus tramadol provided the best post-operative analgesic effects in cats submitted to orchiectomy lasting 6 h and could also be a choice to consider for longer surgical procedures. [ABSTRACT FROM AUTHOR]

Published
2023
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32. All we need is the candidate’s face: The irrelevance of information about political coalition affiliation and campaign promises

Author

Lucia Mannetti, Ambra Brizi, Jocelyn Belanger, and Ilaria Bufalari

Subjects
first impressions, political choices, candidate’s face, Psychology, BF1-990, Neurophysiology and neuropsychology, QP351-495
Abstract

Recent research has indicated that judgments of competence based on very short exposure to political candidates’ faces reliably predict electoral success. An unexplored question is whether presenting written information of the kind to which voters are typically exposed during an election alongside candidates’ faces affects competence judgments. We conducted three studies using photographs of 16 pairs of competing politicians in 16 medium-sized towns of northeast Italy as stimuli. Study 1 confirmed the external validity of earlier research in which participants were exposed to candidates’ faces without providing any other information. Study 2a showed that competence judgments were not subject to in-group favoritism: candidates’ faces were presented alongside information about the political coalition to which they belonged (center left; center right) to participants who declared a left or right political orientation. Finally, Study 2c compared the competence inferences made in Study 1 (face-only condition) with those of Study 2a (face plus political coalition label) and with new inferences (Study 2b) based on candidates’ faces plus information about campaign promises (greater equality; lower taxes). The results showed that automatic competence inferences are not substantially modified when relevant written information is presented alongside candidates’ faces.

Published
2016
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33. Sedation quality of alfaxalone associated with butorphanol, methadone or pethidine in cats injected into the supraspinatus or the quadriceps muscle

Author

Giacomo Giannettoni, Giulia Moretti, Laura Menchetti, Arianna Pepe, Federica Bellocchi, Antonello Bufalari, and Sara Nannarone

Subjects
quadriceps, supraspinatus, Meperidine, Mydriasis, Cat Diseases, Injections, Intramuscular, Pregnanediones, pethidine, Quadriceps Muscle, Alfaxalone, Rotator Cuff, sedation, Butorphanol, Cats, Animals, Hypnotics and Sedatives, Anesthesia, Alfaxalone, butorphanol, methadone, pethidine, quadriceps, sedation, supraspinatus, Small Animals, Methadone
Abstract

Objectives The aim of this study was to compare the quality of sedation with three different anaesthetic protocols (alfaxalone combined with butorphanol, methadone or pethidine) administered intramuscularly in cats, and to evaluate the influence of the injection site (between supraspinatus and quadriceps muscles) on the onset and quality of sedation. Methods A total of 151 cats were selected for this study. Cats were sedated with alfaxalone (3 mg/kg) combined with either butorphanol (0.3 mg/kg; n = 50), methadone (0.3 mg/kg; n = 53) or pethidine (5 mg/kg; n = 48). The combination was injected intramuscularly into the supraspinatus (n = 79) or quadriceps muscle (n = 72). The data included a scoring system for the quality of sedation and physiological parameters, such as heart rate (HR), respiratory rate, body temperature and occurrence of mydriasis, monitored during the first 30 mins of anaesthesia. Results The opioid associated with alfaxalone influenced the overall sedation score, the degree of myorelaxation, the occurrence of mydriasis and HR. The overall sedation score was poorer with butorphanol than with methadone ( P = 0.008), and butorphanol induced a lower degree of myorelaxation than methadone ( P = 0.013). The injection into the supraspinatus showed better qualitative results for sedation and a faster onset time (in about 3 mins) than that into the quadriceps ( P Conclusions and relevance All three protocols provided a good quality of sedation and allowed performing the scheduled procedure. Moreover, the injection into the supraspinatus muscle showed superior results in all the qualitative scores of sedation and quicker onset time than that into the quadriceps muscle.

Published
2022

34. Mode-III fatigue of welded joints in steel maritime structures: Weld notch shear stress distributions and effective notch stress based resistance

Author

Bufalari, G. (author), den Besten, J.H. (author), Kaminski, M.L. (author), Bufalari, G. (author), den Besten, J.H. (author), and Kaminski, M.L. (author)

Abstract

The predominant mode-I response of maritime structures can be multiaxial, involving out-of-plane mode-III shear components. Semi-analytical mode-III notch stress distribution formulations have been established for critical details like welded T-joints and cruciform joints, reflecting (non-)symmetry with respect to half the plate thickness. Using a stress distribution formulation based effective notch stress as fatigue strength criterion, the mode-III welded joint mid-cycle fatigue resistance characteristics have been investigated. In comparison to mode-I, the material characteristic length and resistance curve slope estimate suggest the fatigue damage process to be even more an initiation related near-surface phenomenon. Mean shear stress effects seem insignificant., Ship Hydromechanics and Structures

Published
2022
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36. Intracardiac Porcupine Quill Migration in a Dog: Multimodality Imaging Findings and Surgical Management

Author

Antonello Bufalari, Giulia Moretti, Eleonora Monti, Lisa Garofanini, Giovanni Angeli, Francesco Porciello, Maria Chiara Marchesi, and Domenico Caivano

Subjects
Computer tomography, General Veterinary, heart, Hystrix cristata, migrating foreign body, porcupine quill, thoracic surgery, ultrasound
Abstract

The porcupine is a nocturnal quill-bearing rodent common throughout Italy. When threatened, it defends itself by erecting its quills, rattling its tail, and running sideways or backyard into predators. The quills are released upon contact with assailants and tend to migrate into several body tissues or cavities due to the unique inverted cuticles (crenate) directed downwards to the quill base (a sort of “harpoon effect”). Intracardiac migration of porcupine quills has been reported in a few dogs with severe clinical signs. This case report describes a single porcupine quill [Hystrix cristata, (HC)] migration through the heart in a dog and the use of multimodality imaging for the diagnosis and surgical approach. A 4-year-old 25 kg female mixed-breed dog was presented for evaluation of recurrent fever. Transthoracic echocardiographic examination showed a linear, hyperechoic foreign body traversing the interventricular septum from the heart base to the cardiac apex. Computed tomography and transesophageal echocardiography confirmed the presence of a single structure resembling a quill; a later esophageal endoscopy showed no anatomical alterations or mucosal injuries. Following median sternotomy and after accurate localization by intraoperative ultrasound, the quill was successfully removed. The dog had a good recovery without evidence of severe cardiac injury secondary to an intracardiac quill. To the best of the authors’ knowledge, the identification of an intracardiac HC quill by ultrasonography and CT and its successful removal by ultrasound guide has not been previously reported.

Published
2022

38. Mode-III fatigue of welded joints in steel maritime structures

Author

Gabriele Bufalari, Henk den Besten, and Miroslaw Lech Kaminski

Subjects
Mode-III, Stress distribution, Mechanics of Materials, Mechanical Engineering, Modeling and Simulation, Effective notch stress, Welded joints, General Materials Science, Industrial and Manufacturing Engineering, Fatigue
Abstract

The predominant mode-I response of maritime structures can be multiaxial, involving out-of-plane mode-III shear components. Semi-analytical mode-III notch stress distribution formulations have been established for critical details like welded T-joints and cruciform joints, reflecting (non-)symmetry with respect to half the plate thickness. Using a stress distribution formulation based effective notch stress as fatigue strength criterion, the mode-III welded joint mid-cycle fatigue resistance characteristics have been investigated. In comparison to mode-I, the material characteristic length and resistance curve slope estimate suggest the fatigue damage process to be even more an initiation related near-surface phenomenon. Mean shear stress effects seem insignificant.

Published
2022
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39. Is that me or my twin? Lack of self-face recognition advantage in identical twins.

Author

Matteo Martini, Ilaria Bufalari, Maria Antonietta Stazi, and Salvatore Maria Aglioti

Subjects
Medicine, Science
Abstract

Despite the increasing interest in twin studies and the stunning amount of research on face recognition, the ability of adult identical twins to discriminate their own faces from those of their co-twins has been scarcely investigated. One's own face is the most distinctive feature of the bodily self, and people typically show a clear advantage in recognizing their own face even more than other very familiar identities. Given the very high level of resemblance of their faces, monozygotic twins represent a unique model for exploring self-face processing. Herein we examined the ability of monozygotic twins to distinguish their own face from the face of their co-twin and of a highly familiar individual. Results show that twins equally recognize their own face and their twin's face. This lack of self-face advantage was negatively predicted by how much they felt physically similar to their co-twin and by their anxious or avoidant attachment style. We speculate that in monozygotic twins, the visual representation of the self-face overlaps with that of the co-twin. Thus, to distinguish the self from the co-twin, monozygotic twins have to rely much more than control participants on the multisensory integration processes upon which the sense of bodily self is based. Moreover, in keeping with the notion that attachment style influences perception of self and significant others, we propose that the observed self/co-twin confusion may depend upon insecure attachment.

Published
2015
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40. Genome-wide expression of the residual lung reacting to experimental Pneumonectomy

Author

Napolioni, Valerio, primary, Bianconi, Fortunato, additional, Potenza, Rossella, additional, Carpi, Francesco M., additional, Ludovini, Vienna, additional, Picciolini, Matteo, additional, Tofanetti, Francesca R., additional, Bufalari, Antonello, additional, Pallotti, Stefano, additional, Poggi, Camilla, additional, Anile, Marco, additional, Daddi, Niccolò, additional, Venuta, Federico, additional, Puma, Francesco, additional, and Vannucci, Jacopo, additional

Published
2021
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41. A Comparative Study of Intramuscular Alfaxalone- or Ketamine-Based Anesthetic Mixtures in Gray Squirrels Undergoing Gonadectomy: Clinical and Physiologic Findings

Author

Antonello Bufalari, Giulia Moretti, Laura Menchetti, Federica Bellocchi, Sara Nannarone, Sara Nannarone, Giulia Moretti, Federica Bellocchi, Laura Menchetti, and Antonello Bufalari

Subjects
ketamine, viruses, animal diseases, Sedation, Population, anesthesia, behavioral disciplines and activities, Sciurus carolinensis, Sevoflurane, Article, lcsh:Zoology, medicine, Alfaxalone, Anesthesia, Dexmedetomidine, Gonadectomy, Ketamine, Midazolam, Squirrel, lcsh:QL1-991, education, education.field_of_study, lcsh:Veterinary medicine, General Veterinary, alfaxalone, business.industry, dexmedetomidine, Sciurus carolinensi, midazolam, Anesthetic, lcsh:SF600-1100, Animal Science and Zoology, sense organs, medicine.symptom, gonadectomy, business, psychological phenomena and processes, medicine.drug
Abstract

The gray squirrel is one of the most common invasive species in Europe, whose presence is dangerous for the survival of the European red squirrel. To cope with this biological invasion and to safeguard biodiversity, the LIFE+U-SAVEREDS project aims to protect the red squirrel, by limiting the growth of the current population of gray squirrels and simultaneously promoting their eradication with surgical sterilization. This study compares two different anesthetic protocols, including dexmedetomidine (40 &micro, g/kg) and midazolam (0.3 mg/kg) associated with ketamine (15 mg/kg, n = 25 squirrels) or alfaxalone (5 mg/kg, n = 22 squirrels). A blinded investigator evaluated the quality and onset of sedation, intraoperative anesthesia, and recovery, as well as the physiologic parameters for each animal. Alfaxalone provided a good quality of anesthesia with limited cardiovascular effects (p &lt, 0.05) and good intraoperative myorelaxation. Ketamine induced complete relaxation in a shorter time (p &lt, 0.05) and a rapid (p &lt, 0.001) and excellent (p &lt, 0.05) recovery. Despite the overall superiority of ketamine, alfaxalone appeared to be an adequate alternative anesthetic drug that can be administered without requiring intravascular access. It should be rapidly metabolized and excreted, however, it requires the combination of longer acting sedatives/myorelaxants to prevent a poor recovery quality.

Published
2020

45. Seasonal Expression of NGF and Its Cognate Receptors in the Ovaries of Grey Squirrels (Sciurus carolinensis)

Author

Silvia Crotti, Massimo Zerani, Francesco Alessandro Palermo, Cecilia Dall'Aglio, Giulia Moretti, Antonello Bufalari, Daniele Paoloni, Paolo Cocci, Margherita Maranesi, and Francesca Mercati

Subjects
endocrine system, Population, Receptor tyrosine kinase, Article, nerve growth factor, Andrology, reproduction, 03 medical and health sciences, neurotrophic tyrosine kinase receptor 1, 0302 clinical medicine, Follicular phase, lcsh:Zoology, Seasonal breeder, lcsh:QL1-991, Receptor, education, 030304 developmental biology, alien invasive species, 0303 health sciences, education.field_of_study, 030219 obstetrics & reproductive medicine, Sciurus carolinensis, lcsh:Veterinary medicine, General Veterinary, biology, nerve growth factor receptor, biology.organism_classification, Nerve growth factor, nervous system, immunohistochemistry, biology.protein, lcsh:SF600-1100, Animal Science and Zoology, ELISA, real-time PCR, Neurotrophin
Abstract

Simple Summary Invasive alien species pose a significant threat to biodiversity, as once they have adapted to their new environment, they cause the reduction and even extinction of native species. In this framework, the American grey squirrel (Sciurus carolinensis) poses a serious threat to the European red species squirrel (Sciurus vulgaris), especially in the Umbria region of Italy. In fact, an invasive grey squirrel population has adapted well to the Umbrian territory, showing high reproductive success. In addition to its role in the development of the vertebrate nervous system, nerve growth factor (NGF) has recently been found to play an important role in reproduction. In order to investigate the reproductive physiology of female grey squirrels, the ovarian presence, distribution, and gene expression of NGF and its cognate receptors were evaluated during both breeding and nonbreeding seasons. The presence and gene expression of this system at the ovarian level, mainly during the breeding season, confirm the possible involvement of NGF and its receptors in the gonadal activity of this invasive grey squirrel population. Abstract The grey squirrel is an invasive alien species that seriously threatens the conservation of the native red squirrel species. With the aim of characterizing the reproductive physiology of this species due to its great reproductive success, the function of the ovarian nerve growth factor (NGF) system was analyzed in a grey squirrel population living in central Italy. During the breeding and nonbreeding seasons, the ovarian presence, distribution, and gene expression of NGF, neurotrophic tyrosine kinase receptor 1 (NTRK1), and nerve growth factor receptor (NGFR), as well as NGF plasma concentrations, were evaluated in female grey squirrels. NGF was found in the luteal cells and in the thecal and granulosa cells of follicles, while NTRK1 and NGFR were only observed in follicular thecal and granulosa cells. NGF and NGFR transcripts were almost two-fold greater during the breeding season, while no seasonal differences were observed in NTRK1 gene expression. During the breeding season, NGFR was more expressed than NTRK1. Moreover, no changes were observed in NGF plasma levels during the reproductive cycle. The NGF system seems to be involved in regulating the ovarian cycle mainly via local modulation of NGF/NGFR, thus playing a role in the reproductive physiology of this grey squirrel population.

Published
2020
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49. Reproductive Traits of an Invasive Alien Population of Grey Squirrel (Sciurus carolinensis) in Central Italy

Author

Maranesi, Margherita, primary, Bufalari, Antonello, additional, Dall’Aglio, Cecilia, additional, Paoloni, Daniele, additional, Moretti, Giulia, additional, Crotti, Silvia, additional, Manuali, Elisabetta, additional, Stazi, Marica, additional, Bergamasco, Francesca, additional, Cruciani, Deborah, additional, Di Meo, Antonio, additional, Boiti, Cristiano, additional, Zerani, Massimo, additional, and Mercati, Francesca, additional

Published
2020
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