167 results on '"Brullo, Chiara"'
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2. Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-β pathology
3. Anticancer Effects of the Novel Pyrazolyl-Urea GeGe-3
4. Investigations of Antioxidant and Anti-Cancer Activities of 5-Aminopyrazole Derivatives
5. Recent Advances in the Discovery of SIRT1/2 Inhibitors via Computational Methods: A Perspective
6. Computational Methods for the Discovery and Optimization of TAAR1 and TAAR5 Ligands.
7. PDE4D: A Multipurpose Pharmacological Target.
8. Structure–Activity Relationship Studies on Highly Functionalized Pyrazole Hydrazones and Amides as Antiproliferative and Antioxidant Agents
9. New Pyrazolyl Thioureas Active against the Staphylococcus Genus
10. Novel insights on the molecular mechanism of action of the anti-angiogenic pyrazolyl-urea GeGe-3 by functional proteomics
11. A Proteomics Approach Identifies RREB1 as a Crucial Molecular Target of Imidazo–Pyrazole Treatment in SKMEL-28 Melanoma Cells.
12. Imidazo-Pyrazole-Loaded Palmitic Acid and Polystyrene-Based Nanoparticles: Synthesis, Characterization and Antiproliferative Activity on Chemo-Resistant Human Neuroblastoma Cells
13. Antiproliferative Imidazo-Pyrazole-Based Hydrogel: A Promising Approach for the Development of New Treatments for PLX-Resistant Melanoma
14. Indole Antitumor Agents in Nanotechnology Formulations: An Overview
15. Virtual Screening Combined with Enzymatic Assays to Guide the Discovery of Novel SIRT2 Inhibitors
16. Targeting USP-7 by a Novel Fluorinated 5-Pyrazolyl-Urea Derivative
17. Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-beta pathology
18. Amino-Pyrazoles in Medicinal Chemistry: A Review
19. Antimicrobial Evaluation of New Pyrazoles, Indazoles and Pyrazolines Prepared in Continuous Flow Mode
20. Pyrazole-Enriched Cationic Nanoparticles Induced Early- and Late-Stage Apoptosis in Neuroblastoma Cells at Sub-Micromolar Concentrations
21. Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis.
22. Inside the Mechanism of Action of Three Pyrazole Derivatives in Human Platelets and Endothelial Cells
23. Correction: Biological evaluation of pyrazolyl-urea and dihydro-imidazo-pyrazolyl-urea derivatives as potential anti-angiogenetic agents in the treatment of neuroblastoma
24. Hydrogel Formulations of Antibacterial Pyrazoles Using a Synthesized Polystyrene-Based Cationic Resin as a Gelling Agent
25. Nanotechnology for Pediatric Retinoblastoma Therapy
26. Microbiological Screening of 5-Functionalized Pyrazoles for the Future Development of Optimized Pyrazole-Based Delivery Systems
27. Enhanced Antibacterial Activity of a Cationic Macromolecule by Its Complexation with a Weakly Active Pyrazole Derivative
28. The Development of FAK Inhibitors: A Five-Year Update
29. Synthesis and Characterization of Pyrazole-Enriched Cationic Nanoparticles as New Promising Antibacterial Agent by Mutual Cooperation
30. Pyrazole-Based Water-Soluble Dendrimer Nanoparticles as a Potential New Agent against Staphylococci
31. The Development of BTK Inhibitors: A Five-Year Update
32. The Pyrazolyl-Urea Gege3 Inhibits the Activity of ANXA1 in the Angiogenesis Induced by the Pancreatic Cancer Derived EVs
33. Preparation and Physicochemical Characterization of Water-Soluble Pyrazole-Based Nanoparticles by Dendrimer Encapsulation of an Insoluble Bioactive Pyrazole Derivative
34. New Series of Pyrazoles and Imidazo-Pyrazoles Targeting Different Cancer and Inflammation Pathways
35. Btk Inhibitors: A Medicinal Chemistry and Drug Delivery Perspective
36. Nanotechnology of Tyrosine Kinase Inhibitors in Cancer Therapy: A Perspective
37. Breakthroughs in medicinal chemistry: new targets and mechanisms, new drugs, new hopes-7
38. Biological evaluation of pyrazolyl-urea and dihydro-imidazo-pyrazolyl-urea derivatives as potential anti-angiogenetic agents in the treatment of neuroblastoma
39. Pyrazolyl-Ureas as Interesting Scaffold in Medicinal Chemistry
40. Insight into GEBR-32a: Chiral Resolution, Absolute Configuration and Enantiopreference in PDE4D Inhibition
41. New Hybrid Pyrazole and Imidazopyrazole Antinflammatory Agents Able to Reduce ROS Production in Different Biological Targets
42. Phosphodiesterase 4D inhibition boosts remyelination in multiple sclerosis
43. The pyrazolyl-urea GeGe3 inhibits tumor angiogenesis and reveals dystrophia myotonica protein kinase (DMPK)1 as a novel angiogenesis target
44. Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer’s disease
45. Pyrazole-Based Water-Soluble Dendrimer Nanoparticles as a Potential New Agent against Staphylococci.
46. Combined Effects of Methyldopa and Flavonoids on the Expression of Selected Factors Related to Inflammatory Processes and Vascular Diseases in Human Placenta Cells—An In Vitro Study.
47. Synthesis and Biological Evaluation of Analogs of Didehydroepiandrosterone as Potential New Anticancer Agents.
48. Effects of Pyrrole-Imidazole Polyamides Targeting Human TGF-β1 on the Malignant Phenotypes of Liver Cancer Cells.
49. Evaluation of the Anticancer Activities of Novel Transition Metal Complexes with Berenil and Nitroimidazole.
50. Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis
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