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4. Targeting Pancreatic Islet NLRP3 Improves Islet Graft Revascularization

Author

Wrublewsky, Selina, primary, Speer, Thimoteus, additional, Nalbach, Lisa, additional, Boewe, Anne S., additional, Pack, Mandy, additional, Alansary, Dalia, additional, Roma, Leticia P., additional, Hoffmann, Markus D.A., additional, Schmitt, Beate M., additional, Weinzierl, Andrea, additional, Menger, Michael D., additional, Laschke, Matthias W., additional, and Ampofo, Emmanuel, additional

Published
2022
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5. Inhibition of CK2 Reduces NG2 Expression in Juvenile Angiofibroma

Author

Boewe, Anne S., primary, Wemmert, Silke, additional, Kulas, Philipp, additional, Schick, Bernhard, additional, Götz, Claudia, additional, Wrublewsky, Selina, additional, Montenarh, Mathias, additional, Menger, Michael D., additional, Laschke, Matthias W., additional, and Ampofo, Emmanuel, additional

Published
2022
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6. sj-docx-1-tej-10.1177_20417314221109957 – Supplemental material for Adipose tissue-derived microvascular fragments promote lymphangiogenesis in a murine lymphedema model

Author

Frueh, Florian S, Gassert, Laura, Scheuer, Claudia, Müller, Andreas, Fries, Peter, Boewe, Anne S, Ampofo, Emmanuel, Rübe, Claudia E, Menger, Michael D, and Laschke, Matthias W

Subjects
110599 Dentistry not elsewhere classified, FOS: Clinical medicine, FOS: Biological sciences, 69999 Biological Sciences not elsewhere classified
Abstract

Supplemental material, sj-docx-1-tej-10.1177_20417314221109957 for Adipose tissue-derived microvascular fragments promote lymphangiogenesis in a murine lymphedema model by Florian S Frueh, Laura Gassert, Claudia Scheuer, Andreas Müller, Peter Fries, Anne S Boewe, Emmanuel Ampofo, Claudia E Rübe, Michael D Menger and Matthias W Laschke in Journal of Tissue Engineering

Published
2022
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8. Protein Kinase CK2 Contributes to Glucose Homeostasis by Targeting Fructose-1,6-Bisphosphatase 1.

Author

Pack, Mandy, Gulde, Tim Nikolai, Völcker, Michelle Victoria, Boewe, Anne S., Wrublewsky, Selina, Ampofo, Emmanuel, Montenarh, Mathias, and Götz, Claudia

Subjects
PROTEIN kinase CK2, HOMEOSTASIS, GLUCOSE, CARBOHYDRATE metabolism, METABOLIC regulation, INSULIN
Abstract

Glucose homeostasis is of critical importance for the survival of organisms. It is under hormonal control and often coordinated by the action of kinases and phosphatases. We have previously shown that CK2 regulates insulin production and secretion in pancreatic β-cells. In order to shed more light on the CK2-regulated network of glucose homeostasis, in the present study, a qRT-PCR array was carried out with 84 diabetes-associated genes. After inhibition of CK2, fructose-1,6-bisphosphatase 1 (FBP1) showed a significant lower gene expression. Moreover, FBP1 activity was down-regulated. Being a central enzyme of gluconeogenesis, the secretion of glucose was decreased as well. Thus, FBP1 is a new factor in the CK2-regulated network implicated in carbohydrate metabolism control. [ABSTRACT FROM AUTHOR]

Published
2023
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