1. Safety profile of treatment with greenlight versus Thulium Laser for benign prostatic hyperplasia.
- Author
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Campobasso, Davide, Barbieri, Antonio, Bocchialini, Tommaso, Pozzoli, Gian Luigi, Dinale, Francesco, Facchini, Francesco, Grande, Marco Serafino, Kwe, Jean Emmanuel, Larosa, Michelangelo, Guarino, Giulio, Mezzogori, Davide, Simonetti, Elisa, Ziglioli, Francesco, Frattini, Antonio, and Maestroni, Umberto Vittorio
- Subjects
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BENIGN prostatic hyperplasia , *THULIUM , *URINARY stress incontinence , *RANDOMIZED controlled trials , *LASERS - Abstract
Objective: The major strengths of surgical treatment of benign prostatic hyperplasia with laser are reduced morbidity compared to endoscopic resection. No studies analysed the different risk of intra/peri-operative events between patients undergoing Thulium and GreenLight procedures. Materials and methods: We retrospectively reviewed 100 consecutive cases undergoing GreenLight vaporization and Thulium procedures performed during the learning curve of two expert endoscopic surgeons. Pre-operative data, intra and post-operative events at 90 days were analysed. Results: Patients on antiplatelet/anticoagulant therapy were predominant in the Green group (p < 0.0001). Rates of blood transfusion (p < 0.0038), use of resectoscope (p < 0.0086), and transient stress urinary incontinence were statistically higher in the Thulium group. On the contrary conversions to TURP (p < 0.023) were more frequent in GreenLight patients. Readmissions were more frequently necessary in GreenLight group (24%) vs. Thulium group (26.6%). The overall complication rate in GreenLight and Thulium groups were 31% and 53% respectively; Clavien 3b complications were 13% in Thulium patients versus 1% in GreenLight patients. Conclusions: GreenLight and Thulium treatments show similar safety profiles. Randomized controlled trial are needed to better clarify the rate of major complications in Thulium group, and the incidence of post-operative storage symptoms in these patients' populations. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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