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We aim to study the temporal patterns of activity in points of interest of cities around the world. In order to do so, we use the data provided by the online location-based social network Foursquare, where users make check-ins that indicate points of interest in the city. The data set comprises more than 90 million check-ins in 632 cities of 87 countries in 5 continents. We analyzed more than 11 million points of interest including all sorts of places: airports, restaurants, parks, hospitals, and many others. With this information, we obtained spatial and temporal patterns of activities for each city. We quantify similarities and differences of these patterns for all the cities involved and construct a network connecting pairs of cities. The links of this network indicate the similarity of temporal visitation patterns of points of interest between cities and is quantified with the Kullback-Leibler divergence between two distributions. Then, we obtained the community structure of this network and the geographic distribution of these communities worldwide. For comparison, we also use a Machine Learning algorithm-unsupervised agglomerative clustering-to obtain clusters or communities of cities with similar patterns. The main result is that both approaches give the same classification of five communities belonging to five different continents worldwide. This suggests that temporal patterns of activity can be universal, with some geographical, historical, and cultural variations, on a planetary scale., (© 2023. The Author(s).)

Aims: To evaluate the prevalence and type of adverse drug reactions (ADRs), together with associated risk factors, among Cuban COVID-19 patients treated with chloroquine (CQ), lopinavir/ritonavir (LPV/r), or interferon α 2b (IFN α 2b), according to the Cuban protocol., Materials and Methods: A prospective descriptive analysis of ADRs was performed on 200 COVID-19 patients who were admitted consecutively to three hospitals in Havana and Pinar del Río from April to July 2020. Information on demographics, ADRs, outcomes, behavioral, and health-related factors was collected using a validated questionnaire and clinical records. Each potential ADR case was assessed for causality based on the WHO-UMC algorithm, concomitant drug influences, and the presence of any drug-drug interactions (DDI)., Results: The total frequency of ADRs was 55%, with predominantly gastrointestinal disorders and general symptoms (23% vs 20%). 95.1% of ADRs occurred within 10 days after treatment and 42 potential DDI in 55.5% of patients (61/110) were observed. The prevalence of ADRs was: 44%, 30.4%, and 26.4% for IFN α 2b, LPV/r, and CQ, respectively. Sex (odds ratio (OR): 0.40 (95% confidence interval (CI): 0.211-0.742), age (OR: 2.36 (95% CI: 1.02-5.44)), and underlying diseases (OR: 0.12 (95% CI: 0.06-0.23)) were independently associated factors for ADRs ( P < 0.05)., Conclusions: The frequency of ADRs and potential DDI was high compared to their use during nonpandemic times (e.g., for malaria, HIV, or inflammatory diseases). The safety profile of these drugs when used for COVID-19 treatment showed similar characteristics. Comorbidities, age >37 years old, and female sex were associated with ADRs., Competing Interests: The authors declare that there are no conflicts of interest regarding the publication of this paper., (Copyright © 2023 Lizette Gil-del-Valle et al.)

Background & Aims: Vascular liver diseases (VLDs) are represented mainly by portosinusoidal vascular disease (PSVD), noncirrhotic splanchnic vein thrombosis (SVT), and Budd Chiari syndrome (BCS). It is unknown whether patients with VLDs constitute a high-risk population for complications and greater coronavirus disease 2019 (COVID-19)-related mortality from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Our objective was to assess the prevalence and severity of SARS-CoV-2 infection among patients with VLDs, as well as to assess its impact on hepatic decompensation and survival., Methods: This is an observational international study analyzing the prevalence and severity of SARS-CoV-2 infection in VLDs between March 2020 and March 2021, compared with the general population (GP). Patients from Spain (5 centers; n = 493) and France (1 center; n = 475) were included., Results: Nine hundred sixty-eight patients were included: 274 with PSVD, 539 with SVT, and 155 with BCS. Among them, 138 (14%) were infected with SARS-CoV-2: 53 with PSVD, 77 with SVT, and 8 with BCS. The prevalence of SARS-CoV-2 infection in patients with PSVD (19%) and SVT (14%) was significantly higher than in the GP (6.5%; P < .05), whereas it was very similar in patients with BCS (5%). In terms of infection severity, patients with VLDs also presented a higher need of hospital admission (14% vs 7.3%; P < .01), intensive care unit admission (2% vs 0.7%; P < .01), and mortality (4% vs 1.5%; P < .05) than the GP. Previous history of ascites (50% vs 8%; P < .05) and post-COVID-19 hepatic decompensation (50% vs 4%; P < .05) were associated with COVID-19 mortality., Conclusions: Patients with PSVD and SVT could be at higher risk of infection by SARS-CoV-2 and at higher risk of severe COVID-19 disease., (Copyright © 2022 AGA Institute. Published by Elsevier Inc. All rights reserved.)

This study aimed to assess the effect of biomodification before adhesive procedures on the tooth-restoration interface of class V restorations located in caries-simulated vs. sound dentin, and the quality of dentin surface by time-of-flight secondary ion mass spectrometry (ToF-SIMS). Class V cavities located on cervical dentin were prepared on the buccal surfaces of extracted human molars under the simulation of intratubular fluid flow. Two dentin types, i.e., sound and demineralized by formic-acid, were biomodified with 1% riboflavin and calcium phosphate (CaP) prior to the application of a universal adhesive (Clearfil Universal Bond) in etch and rinse or self-etch mode, and a conventional micro hybrid composite (Clearfil APX). Restorations were subjected to thermo mechanical fatigue test and percentages of continuous margins (% CM) before/after fatigue were compared. Bio modification of dentin surfaces at the molecular level was analyzed by Time-of-Flight Secondary Mass Spectometry (ToF-SIMS). % CM were still significantly higher in tooth-restoration interfaces on sound dentin. Meanwhile, biomodification with riboflavin and CaP had no detrimental effect on adhesion and in carious dentin, it improved the % CM both before and after loading. Etching carious dentin with phosphoric acid provided with the lowest results, leading even to restoration loss. The presence of molecule fragments of riboflavin and CaP were detected by ToF-SIMS, evidencing dentin biomodification. The adhesive interface involving carious dentin could be improved by the use of a collagen crosslinker and CaP prior to adhesive procedures.

Using a community-based participatory approach, we developed a film to promote HIV testing among young men who have sex with men (MSM) in Bogotá. Using a 5-step process to develop the intervention, we conducted 11 focus groups with MSM (n = 141) to receive community feedback at each step. To evaluate the intervention we recruited 300 young MSM to complete a baseline survey in December 2017. Between February-June 2018, 63 participants watched the film and completed a post-viewing survey, which showed the intervention was acceptable for the target population. Between August-December 2018, 48 MSM who watched the film and 47 who did not (control group) completed a follow-up survey. To obtain preliminary evidence of the efficacy of the intervention, we assessed the main effect of time (baseline vs. follow-up) and the interaction between time and group (intervention vs. control) on HIV testing uptake and intentions, and knowledge of HIV transmission dynamics and HIV-related rights. Knowledge of HIV rights increased from baseline to follow-up in the intervention group only. HIV Knowledge increased for both groups. HIV testing intentions increased significantly more for non-gay-identified men in the intervention group, but the overall effect of the intervention was not significant. Testing uptake did not change.

Microtiter plate-based bacterial biofilm assay is frequently used to study bacterial biofilm development and growth. While this assay is simple and relatively high-throughput, it frequently shows difficulty in establishing robust biofilm attachment in the wells. We report that the consistency of bacterial biofilm assays carried out in microtiter plates subjected to abrasive treatment, by sandblasting or drill press grinding, is significantly improved in a Pseudomonas fluorescens Pf0-1 model. Scanning electron microscopy imaging suggests that the treated surfaces could provide points of attachment to facilitate the recruitment of bacteria in the initial phase of biofilm colony establishment. The sandblast treated polypropylene, but not polystyrene, plates were found suitable in studying the impact of flavonoid quercetin on the biofilm formation in Bacillus subtilis FB17. Further investigation revealed that due to the hydrophobicity of the polystyrene surfaces, a greater amount of quercetin was adsorbed on the plate surface, effectively lowering the concentration of the flavonoid in solution., Competing Interests: There are no conflicts to declare., (This journal is © The Royal Society of Chemistry.)

Background: We aimed to assess recent Latin American medical school graduates' knowledge and attitudes about OSA and examine whether their knowledge and attitudes about OSA differed from practicing physicians., Methods: Recent medical graduates completed the Spanish translation of the OSA Knowledge and Attitudes (OSAKA) questionnaire at the 2013 national primary-care residency-placement meeting in Ecuador. The OSAKA includes 18 knowledge and five attitudinal items about OSA. We compared recent graduates' data with data collected in 2010-2011 from practicing physicians using chi-square tests of associations among categorical variables and analysis of variance of differences in mean knowledge and attitude scores. Unadjusted logistic regression models tested the odds that recent graduates (vs. practicing physicians) answered each item correctly., Results: Of 265 recent graduates, 138 (52.1%) were male, and mean age was 25.9 years. Although mean knowledge was low overall, scores were lower for recent graduates than for the 367 practicing physicians (53.5% vs. 60.4%;  p  < 0.001). Practicing physicians were significantly more likely to answer specific items correctly with one exception-recent graduates were more likely to know that < 5 apneas-hypopneas/h is normal (OR 1.47, 1.03-2.07). Physicians in practice attributed greater importance to OSA as clinical disorder and the need for identifying patients with OSA; but recent graduates reported greater confidence in managing patients with OSA and CPAP., Conclusions: OSA-focused educational interventions during medical school should help to improve recent medical graduates' abilities to diagnose and treat OSA. We recommend a greater number of hours of medical students' exposure to sleep education., Competing Interests: The present study was approved by Ethic Committee of Clinica Kennedy.Not applicable.The authors declare that they have no competing interests.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

To date, 17 circumbinary planets have been discovered. In this paper, we focus our attention on the stability of the Kepler circumbinary planetary systems with only one planet, i.e. Kepler-16, Kepler-34, Kepler-35, Kepler-38, Kepler-64 and Kepler-413. In addition to their intrinsic interest, the study of such systems is an opportunity to test our understanding of planetary system formation and evolution around binaries. The investigation is done by means of numerical simulations. We perform numerical integrations of the full equations of motion of each system with the aim of checking the stability of the planetary orbit. The investigation of the stability of the above systems consists of three numerical experiments. In the first one, we perform a long-term (1 Gyr) numerical integration of the nominal solution of the six Kepler systems under investigation. In the second experiment, we look for the critical semimajor axis of the six planetary orbits, and finally, in the third experiment, we construct two-dimensional stability maps on the eccentricity-pericentre distance plane. Additionally, using numerical integrations of the nominal solutions we checked if these solutions were close to the exact resonance. [ABSTRACT FROM AUTHOR]

Background: Migration is common among transgender women (TGW), often driven by the desire to escape stigma, find acceptance, establish new connections, access body modifications, or enter new avenues of sex work. Given the heightened mobility of TGW, they are mostly vulnerable to human immunodeficiency virus (HIV) due to migration. This study aimed to evaluate the association between in-country migration and HIV infection among TGW in Northeast Brazil., Methods: The DIVAS was a cross-sectional, multicity study investigating risk behaviors and sexually transmitted infections (STI) among TGW in 2016-2017. A total of 864 TGW were recruited through respondent-driven sampling from three capital cities in Northeast Brazil. Logistic regression estimating odds ratios (OR) and 95% confidence intervals (CI) was used to assess the relationship between in-country migration and HIV infection., Results: The prevalence of HIV among TGW was 24.5%, 21.4% among those aged 18-34 and 36.1% among those ≥ 35 years old. In-country migration increased the odds of HIV infection among TGW aged 18-34 years (OR = 1.84; 95%CI:1.04-3.27) and even higher among those aged ≥ 35y old (OR = 3.08; 95%CI:1.18-8.04)., Conclusions: These data reinforce the pressing need for public health policies that provide comprehensive access and strategies for demand creation for HIV/AIDS prevention and care for TGW who are already highly vulnerable to infection., (© 2024. The Author(s).)

The discrete element method (DEM) is a vital numerical approach for analyzing the mechanical behavior of elastoplastic wet sand. However, parameter uncertainty persists within the mapping between constitutive relationships and inherent model parameters. We propose a Parameter calibration neural network based on Attention, Retention, and improved Transformer for Sequential data (PartsNet), which effectively captures the nonlinear mechanical behavior of wet sand and obtains the optimal parameter combination for the Edinburgh elasto-plastic adhesion constitutive model. Variational autoencoder-based principal component ordering is employed by PartsNet to reduce the high-dimensional dynamic response and extract critical parameters along with their weights. Gated recurrent units are combined with a novel sparse multi-head attention mechanism to process sequential data. The fusion information is delivered by residual multilayer perceptron, achieving the association between sequential response and model parameters. The errors in response data generated by calibrated parameters are quantified by PartsNet based on adaptive differentiation and Taylor expansion. Remarkable calibration capabilities are exhibited by PartsNet across six evaluation indicators, surpassing seven other deep learning approaches in the ablation test. The calibration accuracy of PartsNet reaches 91.29%, and MSE loss converges to 0.000934. The validation experiments and regression analysis confirmed the generalization capability of PartsNet in the calibration of wet sand. The improved sparse attention mechanism optimizes multi-head attention, resulting in a convergence speed of 21.25%. PartsNet contributes to modeling and simulating the precise mechanical properties of complex elastoplastic systems and offers valuable insights for diverse engineering applications. [ABSTRACT FROM AUTHOR]

Research on capturing human mobility patterns for efficient and sustainable urban planning has been widely conducted. However, studies that unveil spatial context beyond macro-level mobility patterns are relatively scarce. This study aims to analyze the spatiotemporal human meta-mobility patterns with rich context using POI data in Seoul from comprehensive perspectives. As a result, the floating population of Seoul exhibits regular and irregular cyclical mobility patterns on weekdays and weekends, respectively, stemming from the periodicity of the dominant POIs. Additionally, graph construction based on mobility similarity and their regional clustering show clusters vary by POIs but are generally divided into peripheral and central regions of Seoul. This indicates that socioeconomic factors cannot be ignored when understanding human mobility patterns. This helps to provide scientific evidence to support policy recommendations towards greenways and sustainable urban mobility systems, such as quantitative disparity of greenways, qualitative issues of greenways in the central areas, and inequality in cultural consumption. Addressing key considerations through targeted policies could significantly improve the overall quality of life for urban residents. We expect this study to lay the groundwork for future research that aims to understand realistic human mobility patterns with a rich context. [ABSTRACT FROM AUTHOR]

The gyratory crusher is one of the most important mineral processing assets in the comminution circuit, and its production performance directly impacts the circuit throughput. Due to its higher energy utilisation rate for rock breakage than semi-autogenous (SAG/AG) milling, it is a common practice in operations to promote and optimise primary crushing before the downstream capacity can be enhanced. This study aims to develop a discrete element modelling (DEM) and multibody dynamics (MBD) cosimulation framework to optimise the performance of the gyratory crusher. An MBD model was initially established to simulate the gyratory crusher's drivetrain system. A GPU-based DEM was also developed with a parallel bond model incorporated to simulate the particle breakage behaviour. Coupling of the MBD and GPU-based DEM resulted in a cosimulation framework based on the Function Mock-up Interface. An industrial-scale gyratory crusher was selected to test the developed numerical framework, and results indicated that the developed method was capable of modelling normal and choked working conditions. The outcome of this study enabled more realistic gyratory crusher improvement and optimisation strategies for enhanced production. [ABSTRACT FROM AUTHOR]

In this study, two types of recycling scenarios are assessed for spent battery materials using froth flotation. The first is for a single cathode chemistry and would be considered as the most likely scenario for a large battery manufacturer, who takes back their own batteries for reprocessing. The second scenario is for mixed cathode chemistry, and this would be the most likely scenario for regional reprocessing. The mixed spent battery materials assessed in this work were sourced from such an industrial recycling operation in Australia. Good results were obtained for both recycling scenarios. The anode recovery and anode grade in the final concentrate for both materials evaluated were for the single spent battery material 80.1% and 90.3%, respectively, and for the mixed spent battery material, 77.4% and 82.0%, respectively. For the final tailings, the cathode grades for both materials tested were 93.9% and 87.1%, respectively, with the lower grade for the mixed spent battery attributed to the high content of impurities in the original material. These results highlight the importance of the preprocessing ahead of the flotation process. The results confirm froth flotation as a feasible technique that can be used to achieve the bulk of the separation. [ABSTRACT FROM AUTHOR]

Pathogens can be collected from air and detected in samples by many methods. However, merely detecting pathogens does not answer whether they can spread disease. To fully assess health risks from exposure to airborne pathogens, the infectivity of those agents must be assessed. Air samplers which operate by growing particles through water vapor condensation and subsequently collecting them into a liquid medium have proven effective at conserving the viability of microorganisms. We present a study that assessed performance improvement of one such sampler, BioSpot-GEM™, gained by augmenting it with an upstream virtual impactor (VI) designed to concentrate particles in aerosols. We demonstrate that such an integrated unit improved the collection of live Escherichia coli by a median Concentration Factor (CF) of 1.59 and increased the recovery of viable human coronavirus OC43 (HCoV OC43) by a median CF of 12.7 as compared to the sampler without the VI. Our results also show that OC43 can be concentrated in this way without significant loss of infectivity. We further present that the small BioSpot-GEM™ bioaerosol sampler can collect live E. coli at an efficiency comparable to the larger BioSpot-VIVAS™ bioaerosol sampler. Our analyses show potential benefits toward improving the collection of viable pathogens from the air using a more portable water-based condensation air sampler while also highlighting challenges associated with using a VI with concentrated bioaerosols. This work can aid further investigation of VI usage to improve the collection of pathogens from air, ultimately to better characterize health risks associated with airborne pathogen exposures. Copyright © 2024 American Association for Aerosol Research [ABSTRACT FROM AUTHOR]

Necropsy findings were reviewed from wild birds submitted to the Charles Darwin Research Station, Santa Cruz Island, Galápagos Archipelago between 2004 and 2006. One hundred and ninety cases from 27 different species were submitted, and 178 of these cases were evaluated grossly or histologically. Trauma and trauma-related deaths (n=141) dominated necropsy submissions. Infectious causes of avian mortality included myiasis due to Philornis sp. (n=6), avian pox (n=1), and schistosomosis (n=1).

Innovation in comminution is expected to continue unabated to address the inefficiencies that are inherent in comminution circuits. The rotary offset crusher (ROC) is a new comminution device with a promising performance potential in terms of throughput due to the enhanced speed of transportation induced by the centrifugal force of the discs. However, the processes driving the comminution of particles trapped in the conical space between the two discs of the crusher are not fully understood. To gain a better insight into the comminution process in this device, discrete element modeling (DEM) simulations were conducted to study the breakage of a single particle for the crusher operated under two different dynamic conditions, i.e., (1) a stationary top disc and (2) both discs rotating at the same speed. For both scenarios, the speed of the discs was varied between 550 and 2350 rpm. Experimental testwork was also conducted with the laboratory prototype to generate the data that were used to calibrate the breakage parameters of the Ab × t10 breakage model. Simulations were performed using polyhedral UG2 ore particles that were generated with the in-built particle generator in the DEM simulator. The simulated ROC, which is operated with both discs rotating, outperformed the ROC with a stationary top disc in terms of the specific input energy and throughput. The crusher with a stationary top disc is characterized by high shear forces (suggesting a higher wear rate), specific input energies greater than 1 kWh/t, and low throughputs (<50 kg/h). The ROC operated with a stationary disc is not recommended for hard rock applications due to expected excessive wear of crushing surfaces and higher energy consumption. The freewheeling discs are recommended, but there is scope to optimize the crusher performance in terms of the power draw, size reduction, and throughput by manipulating the difference between the speeds of the discs. There is also scope to optimize the crusher performance when it is simulated with many particles. Once the full performance potential of the ROC is established, it will then be important to benchmark it against the existing crushers in the minerals industry as well as other industries where crushers are used. [ABSTRACT FROM AUTHOR]

The decays Λ b 0 → Λ c + D ¯ (∗) 0 K - and Λ b 0 → Λ c + D s ∗ - are observed for the first time, in proton-proton collision data at s = 13 Te V , corresponding to an integrated luminosity of 5.4 fb - 1 collected with the LHCb detector. Their ratios of branching fractions with respect to the Λ b 0 → Λ c + D s - mode are measured to be B Λ b 0 → Λ c + D ¯ 0 K - B Λ b 0 → Λ c + D s - = 0.1908 - 0.0034 + 0.0036 - 0.0018 + 0.0016 ± 0.0038 , B Λ b 0 → Λ c + D ¯ ∗ 0 K - B Λ b 0 → Λ c + D s - = 0.589 - 0.017 + 0.018 - 0.018 + 0.017 ± 0.012 , B Λ b 0 → Λ c + D s ∗ - B Λ b 0 → Λ c + D s - = 1.668 ± 0.022 - 0.055 + 0.061 , where the first uncertainties are statistical, the second systematic, and the third, for the Λ b 0 → Λ c + D ¯ (∗) 0 K - decays, are due to the uncertainties on the branching fractions of the D s - → K - K + π - and D ¯ 0 → K + π - decay modes. The measured branching fractions probe factorization assumptions in effective theories and provide the normalization for future pentaquark searches in Λ b 0 → Λ c + D ¯ (∗) 0 K - decay channels. [ABSTRACT FROM AUTHOR]

The flowability and mechanical properties are increasingly crucial in the filling process of deep metal mines with mining depths exceeding 1000 m. The rheological properties of filling slurry in the pipeline were analyzed through rheological tests, L-tube self-flow tests, and semi-industrial loop tests. The results revealed that with an increase in the cement-to-tailings mass ratio (c/t ratio) and mass concentration, the slurry exhibited a higher flow resistance and decreased stowing gradient. During slurry transportation, the pressure loss in the straight pipe was positively correlated with the slurry flow rate, c/t ratio, and mass concentration. A uniaxial compressive strength (UCS) test was conducted to analyze the mechanical properties of the cemented paste backfill containing BMC (CCPB) in both standard and deep-underground curing environments. The UCS of the CCPB showed an increasing trend with the rise in curing age, mass concentration, and the c/t ratio. The comprehensive analysis concluded that when the c/t ratio is 1:4, and the mass concentration is approximately 74%, and parameters such as the slump, bleeding rate, and flowability of the filling slurry meet the criteria for conveying and goaf filling, resulting in a high-strength filling body. [ABSTRACT FROM AUTHOR]

This work introduces an easy method for producing Bi2O3, ZnO, ZnO‐Bi2O3 nanoparticles (NPs) by Biebersteinia Multifida extract. Our products have been characterized through the outcomes which recorded with using powder X‐ray diffractometry (PXRD), Raman, energy dispersive X‐ray (EDX), field emission‐scanning electron microscopy (FE‐SEM), and Fourier‐transform infrared (FT‐IR) techniques. The finding of SEM presented porous structure and spherical morphology for Bi2O3 and ZnO NPs, respectively. While FE‐SEM image of bimetallic nanoparticles showed both porous and spherical morphologies for them; so that spherical particles of ZnO have sat on the porous structure of Bi2O3 NPs. According to the PXRD results, the crystallite sizes of Bi2O3, ZnO and ZnO−Bi2O3 NPs have been obtained 57.69, 21.93, and 43.42 nm, respectively. Antibacterial performance of NPs has been studied on Staphylococcus epidermidis and Pseudomonas aeruginosa bacteria, to distinguish the minimum microbial inhibitory concentration (MIC). Antimicrobial outcomes have showed a better effect for ZnO‐Bi2O3 NPs. Besides, wondering about the cytotoxic action against cancer cell lines, the MTT results have verified the intense cytotoxic function versus breast cancer cells (MCF‐7). According to these observations, obtained products can prosper medical and biological applications. [ABSTRACT FROM AUTHOR]

The Mulberry-Dyke and Fish-Pond System, as a paradigm of traditional Chinese agricultural recycling models, represents a distinct ecosystem. This study focuses on the Mulberry-Dyke and Fish-Pond System in Digang Village, Huzhou, as a typical case. The village serves as a core conservation base for the Huzhou Mulberry-Dyke and Fish-Pond System, hosting the Huzhou Agricultural Science and Technology Development Center's Academician and Expert Workstation and the world's only Mulberry-Dyke and Fish-Pond System Visitor Center. These facilities provide strategic guidance for the conservation, development, planning, and inheritance of the Huzhou Mulberry-Dyke and Fish-Pond System. Considering the unique environment and limitations in data acquisition, this study employed the Analytic Hierarchy Process (AHP) and Fuzzy Comprehensive Evaluation (FCE) to develop an ecosystem service assessment framework encompassing eight aspects and 29 factors assessing the provisioning, regulating, and cultural services of the Mulberry-Dyke and Fish-Pond System. The results indicate that the ecosystem services of the Digang Village Mulberry-Dyke and Fish-Pond System perform at a high level, with cultural services playing a significant role in the overall ecosystem services. The regulating services are relatively weak, highlighting deficiencies in mulberry land management, while the capacity of provisioning services is strong. These findings are crucial for understanding the value of ecosystem services in Digang Village's Mulberry-Dyke and Fish-Pond System, identifying management shortcomings, and providing direction for future assessments and management. This study also offers a practical and effective assessment method for ecosystem service evaluation at smaller scales, where the targeted approach and the presence of significant ambiguity and uncertainty in data are prominent. [ABSTRACT FROM AUTHOR]

Simple Summary: In the present review, information about parasitic helminths (Platyhelminthes, Nematoda, and Acanthocephala) of wild birds in Ecuador is presented based on a PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analysis) systematic search. Data were obtained from ten scientific articles, eight undergraduate theses, and one doctoral dissertation, published between 1966 to 2022. Forty helminth taxa were recorded, and information about the host species, site of infection, and location are provided. This review serves as a compendium for future ecological and epidemiological studies on helminths in wild birds from Ecuador. Parasitic helminths are diverse in wild birds globally, but knowledge about helminths in Ecuadorian avifauna is still fragmentary. In the present review, records about helminths (Platyhelminthes, Nematoda, and Acanthocephala) in Ecuadorian wild birds is presented. A systematic search was carried out using the PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analysis) guideline to compile and summarize the available literature on helminths in wild birds in Ecuador. Data were obtained from ten scientific articles, eight undergraduate theses, and one doctoral dissertation, published between 1966 to 2022. Forty helminth taxa were recorded and information about the host species, site of infection, and location are provided. Nematodes of the genus Ascaridia Dujardin, 1844 were the helminth taxa with the greatest number of records in birds, parasitizing 16 avian species. Also, the Rock Dove (Columba livia; Gmelin, 1789) was the avian species with the greater number of helminth records (n = 11). This review serves as a compendium for future ecological and epidemiological studies on helminths in wild birds in Ecuador and South America. [ABSTRACT FROM AUTHOR]

The Ξ b 0 → Ξ c + D s - and Ξ b - → Ξ c 0 D s - decays are observed for the first time using proton-proton collision data collected by the LHCb experiment at a centre-of-mass energy of s = 13 TeV , corresponding to an integrated luminosity of 5.1 fb - 1 . The branching fractions times the production cross-sections of Ξ b baryons relative to that of Λ b 0 baryon are measured to be R Ξ b 0 Λ b 0 ≡ σ Ξ b 0 σ Λ b 0 × B Ξ b 0 → Ξ c + D s - B Λ b 0 → Λ c 0 D s - = (15.8 ± 1.1 ± 0.6 ± 7.7) % , R Ξ b - Λ b 0 ≡ σ Ξ b - σ Λ b 0 × B Ξ b - → Ξ c 0 D s - B Λ b 0 → Λ c 0 D s - = (16.9 ± 1.3 ± 0.9 ± 4.3) % , where the first uncertainties are statistical, the second systematic, and the third due to the uncertainties on the decay branching fractions of relevant charmed baryons. The masses of Ξ b 0 and Ξ b - baryons are measured to be m Ξ b 0 = 5791.12 ± 0.60 ± 0.45 ± 0.24 MeV / c 2 and m Ξ b - = 5797.02 ± 0.63 ± 0.49 ± 0.29 MeV / c 2 , where the uncertainties are statistical, systematic, and those due to charmed-hadron masses, respectively. [ABSTRACT FROM AUTHOR]

Background: Migration is common among transgender women (TGW), often driven by the desire to escape stigma, find acceptance, establish new connections, access body modifications, or enter new avenues of sex work. Given the heightened mobility of TGW, they are mostly vulnerable to human immunodeficiency virus (HIV) due to migration. This study aimed to evaluate the association between in-country migration and HIV infection among TGW in Northeast Brazil. Methods: The DIVAS was a cross-sectional, multicity study investigating risk behaviors and sexually transmitted infections (STI) among TGW in 2016–2017. A total of 864 TGW were recruited through respondent-driven sampling from three capital cities in Northeast Brazil. Logistic regression estimating odds ratios (OR) and 95% confidence intervals (CI) was used to assess the relationship between in-country migration and HIV infection. Results: The prevalence of HIV among TGW was 24.5%, 21.4% among those aged 18–34 and 36.1% among those ≥ 35 years old. In-country migration increased the odds of HIV infection among TGW aged 18–34 years (OR = 1.84; 95%CI:1.04–3.27) and even higher among those aged ≥ 35y old (OR = 3.08; 95%CI:1.18–8.04). Conclusions: These data reinforce the pressing need for public health policies that provide comprehensive access and strategies for demand creation for HIV/AIDS prevention and care for TGW who are already highly vulnerable to infection. [ABSTRACT FROM AUTHOR]

The integrated development of social media makes enterprise public opinion spread across multiple social platforms. The safety of enterprise public opinion affects the sustainability of enterprise development and social stability. The risk assessment of enterprise public opinion in a cross social media context and sustainable strategies is researched to help enterprises and governments better regulate enterprise public opinion and improve their ability to respond to public opinion. We established an enterprise public opinion risk assessment index system in a cross social media context, and an enterprise public opinion risk assessment model was established by using a combination of the entropy method, TOPSIS, grey relational analysis and Fuzzy C-means method. The research results show that, compared with the context of single social media, the analysis of enterprise public opinion in a cross social media context is more comprehensive and accurate. The risk assessment model of enterprise public opinion proposed in our research is more suitable for the judgment of enterprise public opinion in a cross social media context and can comprehensively and accurately grasp the situation of enterprise public opinion. The management significance of public opinion risk management for the sustainable development of enterprises is also discussed. [ABSTRACT FROM AUTHOR]

Rock fragment size is a key variable in several mining stages such as underground mine design, equipment selection, and mineral processing. In Block Caving, rock fragment sizes are affected by fragmentation during gravity flow in the ore column while ore is being extracted from drawpoints. Additionally, smaller fragments can percolate between large fragments during gravity flow. These two phenomena — rock fragmentation and particle percolation — are not easy to simulate at a large scale in Block Caving. In this paper, a fragmentation model in a cellular automata gravity flow simulator is proposed to model rock fragmentation during flow at large scales. The fragmentation model uses the rock strength, vertical stresses, and travel distance as inputs to estimate the rock breakage and was calibrated with experimental and mine data. The mine scale results show an error of 9% and 7% of the fragmentation in the zones evaluated. This error rate is considered low due to the variability of the phenomena involved. Then, integrating a fragmentation model into a gravity flow simulator can more realistically represent ore fragmentation in caving-mine to generate flow simulations. [ABSTRACT FROM AUTHOR]

A model-independent study of C P violation in B 0 → D K ∗ 0 decays is presented using data corresponding to an integrated luminosity of 9 \,fb - 1 collected by the LHCb experiment at centre-of-mass energies of s = 7 , 8 and 13 \,Te V . The CKM angle γ is determined by examining the distributions of signal decays in phase-space bins of the self-conjugate D → K S 0 h + h - decays, where h = π , K . Observables related to C P violation are measured and the angle γ is determined to be γ = (49 - 19 + 22) ∘ . Measurements of the amplitude ratio and strong-phase difference between the favoured and suppressed B 0 decays are also presented. [ABSTRACT FROM AUTHOR]

Copyright of PODIUM- Revista de Ciencia y Tecnologia en la Cultura Física is the property of Universidad de Pinar del Rio and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Crushers are utilized to break down or crush various components in industrial applications are subjected to high stresses. The crushing process is carried out by a crusher arm located on the crusher itself. The shape and length of the crusher arm inf luence the deformation on the arm and the efficiency of crushing process. During the crushing process, stress concentrations occur at the contact regions and especially at the connection location of the crusher arm and the drive shaft. This study examined the connection of the crusher arm at various positions on the shaft and explored variations in stress. Finite element analysis was used in the analyses. The used material is standard steel that behaved elastically. The stresses changed in a way that was not proportional to the movement of the tangential crusher arm towards the center of the shaft. The d=8 mm and d=24 mm locations are the most suitable places to move the crusher arm rather than the tangential position (d=40 mm). The highest stresses occurred at the corners where the shaft and crusher arm connected and formed a stress concentration. The friction effects on the contact surface were also examined and the increased friction coefficient slightly reduced the stress values of the crusher system, but increased the stresses on the crushed object. Only maximum stress levels that are observed at the surface of the beam are mainly considered. The results regarding the crusher arm are discussed in detail. [ABSTRACT FROM AUTHOR]

Background: Previous studies have indicated the association between stigma and depressive symptoms among frequently stigmatized groups, such as men who have sex with men (MSM). While this association has been suggested in the literature, there is a dearth of evidence that examines whether food insecurity statistically mediates the relationship between stigma and depressive symptoms. Methods: This cross-sectional study conducted between October and December 2022 among a sample of 250 MSM in Kathmandu, Nepal, recruited through respondent-driven sampling. An unadjusted model including the exposure (stigma), mediator (food insecurity), and outcome variables (depressive symptoms) and an adjusted model that controlled for sociodemographic, behavioral, and health-related confounders were used. Bootstrapping was utilized to estimate the coefficients of these effects and the corresponding 95% confidence intervals. Via bootstrap approach, we find out the mediating role of food insecurity in the association between stigma and depressive symptoms. Results: Depressive symptoms, stigma, and food insecurity were 19.6%, 24.4%, and 29.2%, respectively, among MSM. Food insecurity was associated with higher age (b = 0.094; 95% CI = 0.039, 0.150) and monthly income (b = -1.806; 95% CI = -2.622, -0.985). Depressive symptoms were associated with condom-less sex in past six months (b = -1.638; 95% CI = -3.041, -0.092). Stigma was associated with higher age (b = 0.196; 95% CI = 0.084, 0.323) and PrEP uptake (b = 2.905; 95% CI = 0.659. 5.248). Food insecurity statistically mediated 20.6% of the indirect effect of stigma in depressive symptoms. Conclusion: Our findings show that food insecurity affects the relationship between stigma and depressive symptoms in this population. Reducing food insecurity and addressing the stigma surrounding sexual orientation should be a priority when addressing mental health concerns among MSM in Nepal and other resource-limited countries with similar socio-cultural settings. [ABSTRACT FROM AUTHOR]

This study presents a mathematical description of the solid fraction aggregation process in the presence of a flocculant and its result. The basis is a population balance equation. The model is realized in Python language. Verification was carried out using red mud from the investigated enterprise; Flomin AL P 99 VHM was used as a flocculant. The mean square deviation for the parameter "mean aggregate diameter" is equal to 19.88 μm. The time required for the model calculation is about 3 min. The time spent on modeling depends on the number of calculation channels. In this study, 40 channels (20 with PSD source data, and 20 with empty values required for the calculation) were used for the calculation. The time spent on the model calculation is much shorter than the inertia via each of the communication channels for the studied symmetric radial type thickener. A user interface is developed, where the input parameters are the initial pulp particle size distribution, viscosity and density of pulp in the thickener, particle surface area, concentration and flow rate of flocculant, concentration of solid particles, inner diameter and height of the feed well, and simulation time. The result of the simulation is particle size distribution in the feed well of the washer and the mean flocculus diameter. [ABSTRACT FROM AUTHOR]

This document is an editorial for a special issue of the journal Minerals, focusing on the design, modeling, optimization, and control of the flotation process. Flotation is a widely used technique for separating valuable and gangue minerals, but it requires sophisticated control systems that can be costly to implement and maintain. To address these challenges, predictive models have emerged as economically viable solutions. The special issue features papers that explore innovative approaches for modeling, optimizing, and controlling flotation processes, with a focus on hydrodynamic and kinetic models, gas dispersion, and computational tools and algorithms. These techniques have the potential to significantly improve the efficiency of the flotation process and are expected to become effective solutions for monitoring and controlling it in the future. [Extracted from the article]

Understanding the migratory patterns of large whales is of conservation importance, especially in identifying threats to specific populations. Migration ecology, including migratory destinations, movements and site fidelity for humpback whales (Megaptera novaeangliae) remain poorly studied in parts of the range of the Central America population, considered endangered under the United States Endangered Species Act. This study aimed to investigate the migratory destinations of humpback whales sighted at two study sites in Nicaragua, which are part of the Central America population. A ten-year photographic database of humpback whales observed off Nicaragua was combined with citizen science contributions and sightings from dedicated research programs. The resulting image collection was compared with available historical photo identifications and databases using an automated image recognition algorithm. This approach yielded 36 years of photographic identification totaling 431 recaptures in Nicaragua (2006–2008 and 2016–2021) and 2539 recaptures (1986–2020) in both feeding and breeding grounds of 176 unique individuals sighted in Nicaragua. Our results showed that photo-identified whales were recaptured between October and April in breeding grounds and year-round in feeding grounds between British Columbia and California, with peak recaptures between June and October. Our study provided first-time evidence on fine-scale site affinity of individual humpback whales within Nicaraguan waters and to other breeding and feeding grounds. [ABSTRACT FROM AUTHOR]

Copyright of Nova Scientia is the property of Nova Scientia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Dysregulated production of hydrogen sulphide in the human body has been associated with various diseases including cancer, underlining the importance of accurate detection of this molecule. Here, we report the detection of hydrogen sulphide using fluorescence-emission enhancement of two 1,8-naphthalimide fluorescent probes with an azide moiety in position 4. One probe, serving as a control, featured a methoxyethyl moiety through the imide to evaluate its effectiveness for hydrogen sulphide detection, while the other probe was modified with (3-aminopropyl)triethoxysilane (APTES) to enable direct covalent attachment to an optical fibre tip. We coated the optical fibre tip relatively homogeneously with the APTES-azide fluorophore, as confirmed via x-ray photoelectron spectroscopy (XPS). The absorption and fluorescence responses of the control fluorophore free in PBS were analysed using UV-Vis and fluorescence spectrophotometry, while the fluorescence emission of the APTES-azide fluorophore-coated optical fibres was examined using a simple, low-cost optical fibre-based setup. Both fluorescent probes exhibited a significant increase (more than double the initial value) in fluorescence emission upon the addition of HS− when excited with 405 nm. However, the fluorescence enhancement of the coated optical fibres demonstrated a much faster response time of 2 min (time for the fluorescence intensity to reach 90% of its maximum value) compared to the control fluorophore in solution (30 min). Additionally, the temporal evolution of fluorescence intensity of the fluorophore coated on the optical fibre was studied at two pH values (7.4 and 6.4), demonstrating a reasonable overlap and confirming the compound pH insensitivity within this range. The promising results from this study indicate the potential for developing an optical fibre-based sensing system for HS− detection using the synthesised fluorophore, which could have significant applications in health monitoring and disease detection. [ABSTRACT FROM AUTHOR]

A gyratory crusher is a key mineral processing asset in a comminution circuit. Monitoring and predicting the crusher liner wear is essential to ensure the throughput and product quality are maintained during production. This study developed a digital sensor and a discrete element modelling (DEM)-coupled methodology to monitor and reconstruct the gyratory crusher concave liner wear pattern. The developed digital sensor was able to track and report the live thickness of the specific installation point on a concave liner during operation. A wear reconstruction model was then developed based on the wear intensity obtained using the DEM and digital sensor results. The wear reconstruction model predictive results were subsequently compared with site measurements after 95 days of operation. The results indicated that the wear reconstruction model showed good agreement with measured results in terms of wear zone distribution as well as quantitative wear rate prediction. The outcome of this study can be potentially utilised in the mineral processing industry for plant monitoring and automation. [ABSTRACT FROM AUTHOR]

Water is widely used in the mining industry, particularly in mineral enrichment processes. In the process of magnetic separation or flotation of crushed ore, a concentrate (an enriched product), and tailings (a product with a low content of a useful component) are obtained. One of the main tasks of enrichment processes is the efficient use of water resources. This is achieved by reclaiming and subsequent reusing water contained in ore beneficiation products by extracting it in industrial thickeners. Optimizing this process makes it possible to reduce water usage in the mining industry, reduce costs of mineral enrichment processes, and address extremely urgent environmental protection problems. To evaluate the process of sedimentation of the solid phase in the pulp within the thickener, measurements of parameters of longitudinal ultrasonic oscillations and Lamb waves that have traveled a fixed distance in the pulp and along the measuring surface in contact with it are used. The proposed approach allows for the consideration of pulp density, particle size of the solid phase in the ore material and the dynamics of changes in these parameters in the thickener at the initial stage of the sedimentation process. Based on the obtained values, adjustments can be made to the characteristics of its initial product, leading to reduced water usage and minimized loss of a useful component. [ABSTRACT FROM AUTHOR]

Hemoglobin C (HbC) disease is an uncommon disease that is generally considered benign, causing only occasionally painless hematuria, osteomyelitis, and dental abnormalities. Ocular manifestations have rarely been described in these patients. Here we report a novel ophthalmological manifestation of the disease. A 20-year-old woman presented with progressive visual loss in her right eye due to tractional retinal detachment. The left eye was apparently normal, but wide-field fluorescence angiography showed mild peripheral ischemia with multiple vascular abnormalities. Vitrectomy was performed and the systemic workup revealed the presence of hemoglobinopathy C in heterozygous form. HbC disease can be sight-threating due to retinal proliferation, similar to sickle cell retinopathy. Patients affected with this disease should undergo regular surveillance. Ultra-wide angiography is a helpful examination to detect peripheral ischemia in the earlier stages. [ABSTRACT FROM AUTHOR]