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Made available in DSpace on 2015-04-27T11:55:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2014Bitstream added on 2015-04-27T12:08:42Z : No. of bitstreams: 1 ISSN1809-3957-2014-09-100-174-178.pdf: 807135 bytes, checksum: 124c62c1314f70d8eac86278f3ebaf0f (MD5) O presente trabalho foi realizado com o intuito de contextualizar o impacto do surto da doença de Chagas na comercialização do fruto de açaí no município de Pinheiro-MA. O açaí se destaca devido ao seu aproveitamento integral e por estar associado à agricultura familiar agroextrativista, além de sua importância socioeconômica nas regiões produtoras. É utilizado de inúmeras formas, como planta ornamental no paisagismo; construção rústica de casas e pontes; cobertura de moradias na área rural, remédio; produção de celulose; alimentação humana e animal, dentre outros usos, e sua importância econômica, social e cultural está centrada na produção de frutos e palmitos. O açaí é um fruto de alto valor energético e nutritivo, sendo consumido na região de estudo com farinha de mandioca, tapioca, peixe frito e em forma de suco, sorvete, entre outros. O uso da polpa de açaí generalizou-se em todo o país e o cultivo do açaizeiro e o processamento do seu fruto já ocorrem em vários estados brasileiros. Os métodos utilizados na investigação foram pesquisa documental, observação e aplicação de questionários no município de Pinheiro-MA. Os dados obtidos foram analisados e tabulados, sendo sumarizados em frequência, média e porcentagem. Com a pesquisa, constatouse que as pessoas diagnosticadas com a doença de Chagas foram contaminadas devido à ingestão de alimentos contaminados, algumas delas possivelmente por açaí, oriundo do município de Igarapé Mirim, estado do Pará. Quando os processadores e comerciantes da polpa de açaí foram indagados sobre a forma de transmissão da doença de chagas, quase metade dos entrevistados não soube responder à questão. Além disso, também foi constatado com a pesquisa que houve redução na comercialização da polpa do açaí, quando comparado ao mesmo período do ano anterior ao surto da doença na região. Isto demonstra a necessidade de um trabalho de conscientização da população e dos processadores do suco de açaí quanto às formas de transmissão e prevenção da doença, pois a higienização correta dos frutos ainda é o método mais eficiente de prevenção, sendo de suma importância que o produto passe por um processo de lavagem e de pasteurização. Universidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Engenharia e Tecnologia de Alimentos, Instituto de Biociências Letras e Ciências Exatas de São José do Rio Preto, Sao Jose do Rio Preto, Rua Cristóvão Colombo, 2265, Jardim Nazareth, CEP 15054000, SP, Brasil Universidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Engenharia e Tecnologia de Alimentos, Instituto de Biociências Letras e Ciências Exatas de São José do Rio Preto, Sao Jose do Rio Preto, Rua Cristóvão Colombo, 2265, Jardim Nazareth, CEP 15054000, SP, Brasil

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A informação é fundamental em qualquer processo de negócio. Neste estudo, busca-se definir e qualificar a demanda por informações em um website mantido por uma organização de P&D para o agronegócio. Os dados utilizados consistiram na seqüência de clicks realizados por visitantes entre as páginas dos site, e nas palavras-chave inseridas no seu mecanismo de busca. A discussão dos resultados foi orientada à descoberta de conhecimento que pudesse elevar o nível de personalização e de customização do site estudado. Considerando o contexto atual, onde cada vez mais as organizações tenderão a buscar e interagir com clientes e parceiros através da Web, este estudo revelou aspectos úteis relacionados às atividades de transferência de tecnologia e de marketing para a organização objeto do estudo. Made available in DSpace on 2018-04-18T01:38:44Z (GMT). No. of bitstreams: 1 DemandaREAd2003.pdf: 99340 bytes, checksum: d81d4f0ff0b5f81620c4d387eed25e85 (MD5) Previous issue date: 2003-04-24 Edição especial.

OBJECTIVE: To compare measurements of retinal thickness in eyes with mild nonproliferative retinopathy in patients with type 2 diabetes mellitus using 2 different techniques: the retinal thickness analyzer (RTA) and optical coherence tomography (OCT). METHODS: Twenty-eight eyes from 28 patients with type 2 diabetes mellitus and mild nonproliferative retinopathy were classified according to the Wisconsin grading system by 7-field stereoscopic fundus photography. Ten eyes were classified as level 10 (absence of visible lesions) and 18 as level 20 or 35 (minimal retinopathy). All eyes were examined by the RTA and OCT. Healthy populations were used to establish reference maps for the RTA (n = 14; mean age, 48 years; age range, 42-55 years) and OCT (n = 10; mean age, 56 years; age range, 43-68 years). Reference maps were computed using the means + 2 SDs of the values obtained for each location. Increases in thickness were computed as a percentage of increase over these reference maps. RESULTS: The RTA detected increases in thickness in 1 or more locations in 24 of the 28 diabetic eyes examined, whereas OCT detected increases in only 3 eyes. The percentages of increase detected by the RTA ranged from 0.3% to 73.5%, whereas OCT detected percentages of increase of 0.3% to 4.8%. CONCLUSION: Optical coherence tomography is less sensitive than the RTA in detecting localized increases in retinal thickness in the initial stages of diabetic retinal disease.

Retinal edema should be defined as any increase of water of the retinal tissue resulting in an increase in its volume. It may be of cytotoxic or vasogenic origin. Development of vasogenic macular edema is dependent on a series of factors such as blood pressure, blood-retinal barrier permeability, retinal cell damage, retinal tissue osmotic pressure and retinal tissue compliance. Objective measurements of retinal thickness are now possible using the Retinal Thickness Analyser. Localised measurements of blood-retinal barrier permeability may also be obtained using the Retinal Leakage Analyser, a modified confocal scanning laser fluorometer, while obtaining simultaneously angiographic images of the choroid and retina. These new imaging techniques show that cytotoxic and vasogenic retinal edema may occur independently in the early stages of diabetic retinopathy. These findings offer new perspectives for designing novel therapeutic strategies.

Introduction: Mental illnesses have a large impact on individuals, their families and friends and communities. People living with mental illness often face discrimination and not the least within the health-care system. In this research project people living with mental illness in Switzerland share their stories. Out of these stories the Creating Meaning Theory was developed which sheds light on how the people concerned deal with their life situations. Objectives: The aim of this research project was to explore and evaluate the personal experiences of people living with mental illness and to outline the process of adaptation within a new theory. This new understanding may help health-care providers and nurses to promote an improved quality of life and increased wellbeing. Methodology: A constructivist and reflexive Grounded Theory approach was chosen for the study. Ten participants, people living with mental illness in Switzerland, were interviewed and additional data from various sources were included in the data analysis. Results: Three categories form the theoretical framework of the Creating Meaning Theory, which summarises the experiences of the people interviewed for this study: Constructing explanations refers to the process of participants trying to understand what is going on in their lives. Defining self-identity points out that people living with mental illness provide themselves with an understanding of who they are. Making sense-of-life refers to the aspect, that the participants give situations meaning and take control over them. The findings support existing theories but add a new and unique understanding of people’s experiences in living with mental illness. Conclusions: The Creating Meaning Theory provides a new and unique understanding of the adaptation process to living with mental illness from a service user perspective. It is a non-linear, infinite and ongoing process. Their stories need to be heard, understood and transformed into action in real life, health-care and society.

The aim of this paper is the mathematical study of the interactions between bacterial populations, materials they colonize, and drugs delivered from surfaces where they adhere. Bacteria can cause infections, which are common events in different types of medical implants as, for example, orthopedic prosthesis, and are often responsible for rejection. A controlled drug delivery to fight bacterial adhesion is crucial in reducing infection rates. A strategy recently adopted to address the problem is to deliver therapeutic agents locally by dispersing them into polymeric implant coatings. The mathematical model is composed of a system of three partial differential equations that describe the drug release from a biodegradable polymeric coating and by an ordinary differential equation that governs the density of a bacterial population. The link between the system of partial differential equations and the ordinary differential equation is defined by an integral that represents the mass of drug that is released by the polymeric coating at time t. Quasi-sharp estimates for the bacterial density that give insight into its dependence on the polymeric properties and the drug characteristics are established. Numerical experiments illustrating the behavior of the density of bacteria, depending on the characteristics of the drug-polymeric coating system, are included.

Development of personalized cardiovascular management systems involves automatic identification of the current data as normal or pathological; considering cardiac data as time-series, the illness identification may be performed by seeking similarity between the current patient's time-series data and a reference signal and then proceeding to illness stratification (clustering). Seven of the most common methods of time-series similarity measurement were assessed by imposing 6 types of distortions to the reference signal, considering for each distortion 20 possible variations. This study employed 10 seconds length records of arterial blood pressure signals of healthy subjects, collected from a public database. Then clustering using Partitioning Around Medoids was performed among pathological and non-pathological data considering 3 different clusters. Clustering results confirm usage of the reduced basis Discrete Wavelet Transform resulting from the combination of Haar wavelet decomposition with the Karhunen-Loeve transforms, presenting an accuracy ranging from 76% to 85% when partitioning around Medoids clustering is used. [H2020 - 692023] info:eu-repo/semantics/publishedVersion

The aim of this work is to evaluate the polyphenols composition and the antioxidant activity of methanol extracts of Chamaerops humilis L. Methanol extracts from dried leaves of Chamaerops humilis were prepared using Soxhlet extraction and examined as potential sources of phenolic compounds. Different methods were used to evaluate antioxidant activity of the extracts, including colored (ABTS*+), DPPH radical scavenging assay and reducing power. Total phenolic and flavonoid contents of the extracts were evaluated by Folin-Ciocalteu and aluminum chloride (AlCl3) methods, respectively. Phenolic compositions of the methanol extracts were elucidated by high performance liquid chromatography coupled on-line with tandem mass spectrometry (HPLC-MS/MS). The extract was mainly composed of C-and O-flavones and its O-methylated derivatives. The results suggest that methanol extracts have good potential as sources of bioactive compounds and presents an important antioxidants capacity, which can ensures its potential recommendation for application in the pharmaceutical and nutraceutical sectors. Fundacdo para a Ciencia e a Tecnologia (FCT) [UID/QUI/00100/2013, UID/MULTI/00612/2013, REM2015] info:eu-repo/semantics/publishedVersion

[This corrects the article DOI: 10.3389/fnagi.2023.1161847.]., (Copyright © 2024 Batista, Guimarães, Martins, Moreira, Ambrósio, Castelo-Branco, Serranho and Bernardes.)