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18 results on '"Bartolino, Roberto"'

1. Glioblastoma Treatments with Photo-Nanotherapeutics Induce Massive Devascularization and Tumor Elimination

Author

Ricciardi, Loredana, Chatterjee, Sharmistha, Palermo, Giovanna, Szerb, Elisabeta I., Sanna, Alessia, Palermo, Francesca, Pieroni, Nicola, Fratini, Michela, Bartolino, Roberto, Cedola, Alessia, La Deda, Massimo, and Strangi, Giuseppe

Subjects
Physics - Applied Physics
Abstract

Glioblastoma multiforme (GBM) is one of the deadliest and most aggressive cancers, remarkably resilient to current therapeutic treatments. Here, we report in vivo studies of GBM treatments based on photo-nanotherapeutics able to induce synergistic killing mechanisms. Core-shell nanoparticles have been weaponized by combining the photophysical properties of an Ir(III) complex - a new generation PDT agent - with the thermo-plasmonic effects of resonant gold nanospheres. To investigate the damages induced in GBM treated with these nanosystems and exposed to optical radiation, we recurred to the X-ray phase contrast tomography (XPCT). This high-resolution 3D imaging technique highlighted a vast devascularization process by micro-vessels disruption, which is responsible of a tumor elimination without relapse.

Published
2021

6. Hybrid Nanoparticles as Theranostics Platforms for Glioblastoma Treatment: Phototherapeutic and X-ray Phase Contrast Tomography Investigations

Author

Ricciardi, Loredana, primary, Chatterjee, Sharmistha, additional, Palermo, Giovanna, additional, Szerb, Elisabeta I., additional, Sanna, Alessia, additional, Palermo, Francesca, additional, Pieroni, Nicola, additional, Fratini, Michela, additional, Bartolino, Roberto, additional, Cedola, Alessia, additional, La Deda, Massimo, additional, and Strangi, Giuseppe, additional

Published
2022
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8. Thermo-Plasmonic Killing of Escherichia coli TG1 Bacteria

Author

Annesi, Ferdinanda, primary, Pane, Alfredo, additional, Losso, Maria Adele, additional, Guglielmelli, Alexa, additional, Lucente, Fabrizio, additional, Petronella, Francesca, additional, Placido, Tiziana, additional, Comparelli, Roberto, additional, Guzzo, Maria Grazia, additional, Curri, Maria Lucia, additional, Bartolino, Roberto, additional, and De Sio, Luciano, additional

Published
2019
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10. Plasmonics Meets Biology through Optics

Author

De Sio, Luciano, primary, Caracciolo, Giulio, additional, Annesi, Ferdinanda, additional, Placido, Tiziana, additional, Pozzi, Daniela, additional, Comparelli, Roberto, additional, Pane, Alfredo, additional, Curri, Maria, additional, Agostiano, Angela, additional, and Bartolino, Roberto, additional

Published
2015
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16. Observation of Structural Instabilities in a Sheared Cholesteric

Author

Barbero, Giovanni, Barberi, Rieeardo, Simoni, Francesco, and Bartolino, Roberto

Abstract

Microscopic observations of the onset of structural instabilities in a cholesteric liquid crystal subjected to a static or a slowly periodic shear show that these instabilities are very similar to the buckling instabilities induced by a sudden dilation of the sample.

Published
1984
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17. Liquid crystal laser tuner

Author

Umeton, Cesare, Bartolino, Roberto, Cipparrone, Gabriella, and Simoni, Francesco

Published
1988

18. Virtual unrolling and deciphering of Herculaneum papyri by X-ray phase-contrast tomography

Author

Paola Coan, A. Lamarra, A. Cedola, Lorenzo Massimi, Michele Alessandrelli, Michele Giocondo, Raffaele Giuseppe Agostino, Michela Fratini, Giulia Festa, Carla Andreani, Graziano Ranocchia, Alberto Bravin, Inna Bukreeva, Giuseppe Gigli, Alberto Mittone, Federica Ciuchi, Roberto Bartolino, Vincenzo Formoso, Bukreeva, I, Mittone, A, Bravin, A, Festa, G, Alessandrelli, M, Coan, P, Formoso, V, Agostino, R, Giocondo, M, Ciuchi, F, Fratini, M, Massimi, L, Lamarra, A, Andreani, C, Bartolino, R, Gigli, G, Ranocchia, G, Cedola, A, Agostino, R. G, Bartolino, Roberto, Gigli, Giuseppe, Cedola, A., CNR, Ist Nanotecnol, Rome Unit, I-00195 Rome, Italy, P. N. Lebedev Physical Institute of the Russian Academy of Sciences [Moscow] (LPI RAS), Russian Academy of Sciences [Moscow] (RAS), European Synchrotron Radiation Facility (ESRF), CNR, Ist Cristallog Bari, I-70126 Bari, Italy, Enrico Fermi Center for Study and Research | Museo Storico della Fisica e Centro Studi e Ricerche Enrico Fermi, Univ Roma Tor Vergata, Dipartimento Fis, I-00133 Rome, Italy, CNR, Ist Less Intellettuale Europeo & Storia Idee, I-00161 Rome, Italy, Tech Univ Munich, Dept Phys, D-80799 Munich, Germany, Univ Munich, Fac Med, D-80799 Munich, Germany, CNR, Ist Nanotecnol, Cosenza Unit, I-87036 Arcavacata Di Rende, Cosenza, Italy, Univ Calabria, Dipartimento Fis, I-87036 Arcavacata Di Rende, Cosenza, Italy, CNR, Ist Proc Chim Fis Messina, I-98158 Rome, Italy, Interdisciplinary Ctr B Segre Accademia Nazl Linc, I-001564 Rome, Italy, CNR, Ist Nanotecnol, I-73100 Lecce, Italy, and Museo Stor Fis & Ctr Studi & Ric Enrico Fermi, I-00184 Rome, Italy

Subjects
0301 basic medicine, Computer science, [SDV]Life Sciences [q-bio], Herculaneum papyrus rolls, X-ray phase-contrast tomography, Virtual unrolling, FIS/07 - FISICA APPLICATA (A BENI CULTURALI, AMBIENTALI, BIOLOGIA E MEDICINA), 02 engineering and technology, Ancient history, 03 medical and health sciences, Epicureanism, Microscopy, Phase-Contrast, Cyperus, History, Ancient, Phase contrast tomography, Multidisciplinary, Manuscripts as Topic, Tomography, X-Ray, Virtual unrolling, deciphering,Herculaneum papyri, 021001 nanoscience & nanotechnology, Corrigenda, Settore FIS/07 - Fisica Applicata(Beni Culturali, Ambientali, Biol.e Medicin), Philosophy, 030104 developmental biology, Archaeology, FRELON CAMERA, 0210 nano-technology, Algorithms
Abstract

A collection of more than 1800 carbonized papyri, discovered in the Roman ‘Villa dei Papiri’ at Herculaneum is the unique classical library survived from antiquity. These papyri were charred during 79 A.D. Vesuvius eruption, a circumstance which providentially preserved them until now. This magnificent collection contains an impressive amount of treatises by Greek philosophers and, especially, Philodemus of Gadara, an Epicurean thinker of 1st century BC. We read many portions of text hidden inside carbonized Herculaneum papyri using enhanced X-ray phase-contrast tomography non-destructive technique and a new set of numerical algorithms for ‘virtual-unrolling’. Our success lies in revealing the largest portion of Greek text ever detected so far inside unopened scrolls, with unprecedented spatial resolution and contrast, all without damaging these precious historical manuscripts. Parts of text have been decoded and the ‘voice’ of the Epicurean philosopher Philodemus is brought back again after 2000 years from Herculaneum papyri.

Published
2016
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