Hammad MAM, Barham DW, Osmonov D, Hatzichristodoulou G, van Renterghem K, Andrianne R, Park SH, Kohler TS, Hellstrom WJG, Jenkins L, and Yafi FA
Background: In 2017, a prospective multicenter, multinational, investigational pilot study was conducted examining outcomes using a novel surgical technique, the Mini-Jupette sling, for the management of erectile dysfunction (ED) patients with climacturia and/or minimal stress urinary incontinence (SUI) after prostate procedures. Climacturia has been reported in up to 64% of patients following radical prostatectomy (RP). We sought to report the 5-year outcomes from this original cohort to assess long-term safety and effectivity of the mini-jupette sling in the treatment of ED and concomitant mild SUI and/or climacturia., Methods: This is a single-arm, multicenter, retrospective, observational study. We identified patients who were enrolled in the previous multicenter study with post-RP ED and climacturia and/or mild SUI- 2 PADS PER DAY (PPD) and underwent inflatable penile prosthesis (IPP) insertion with simultaneous placement of a mini-jupette sling. Data were collected including current PPD, subjective improvement in climacturia/SUI, complications, need for revision of IPP or additional urinary incontinence surgery, and date of most recent follow-up. SPSS was used for statistical analysis., Results: Of the original 38 patients, 5 have since died and 10 were lost to follow-up with 23/38 (61%) patients available for evaluation of long-term outcomes. The average follow-up time was 59 months (SD =8.8) with a mean age of 69 years (SD =6.8). Most patients (n=21, 91%) had subjective improvement of SUI and climacturia. One patient with persistent bothersome incontinence underwent artificial urinary sphincter (AUS) placement in 2018 with no complications, while the other is still considering a repeat procedure due to minor but persistent SUI. The mean PPD decreased from 1.4 preoperatively to 0.4 at a mean of 5 years of follow-up. Most patients reported satisfaction in their urinary symptoms with 91% and 73% reporting improvement in SUI and climacturia respectively, compared to 86% and 93% respectively in the original series. One (4.3%) patient had an IPP revision for pump malfunction. There were no device infections reported., Conclusions: The mini-jupette sling appears to be a safe and effective procedure with durable improvements in SUI and climacturia at 5 years of follow-up., Competing Interests: Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://tau.amegroups.com/article/view/10.21037/tau-22-661/coif). The series “Surgical Management of Stress Urinary Incontinence in Men” was commissioned by the editorial office without any funding or sponsorship. DO receives consulting fees from Coloplast, Intuitive Surgical, Fidelis; KR receives consulting fees from Boston Scientific, Coloplast, Rigicon; RA receives consulting fees from Boston Scientific, Coloplast; SHP receives consulting fees from Coloplast; TK serves as an unpaid Associate Editor-in-Chief of Translational Andrology and Urology and he receives consulting fees from Coloplast; WH serves as an unpaid Editorial Board Member of Translational Andrology and Urology, and he receives consulting fees from Acerus Pharma, Boston Scientific, Coloplast, Endo, Jazz Pharmaceuticals, Gilead, Promescent, Theralogix; LJ receives consulting fees from Hims & Hers Health Inc; FY receives consulting fees from Coloplast, Clarus Therapeutics, Antares Pharma, Acerus. The authors have no other conflicts of interest to declare., (2023 Translational Andrology and Urology. All rights reserved.)