Search

Your search keyword '"BIGI, DANIELE"' showing total 30 results
Start Over Author "BIGI, DANIELE" Search Limiters Full Text
30 results on '"BIGI, DANIELE"'

1. Chapter I segni dell’Arco di Gallieno a Roma

Author

Carpiceci, Marco, Bigi, Daniele, and Schiavo, Antonio

Subjects
Discipline of representation, History, Semiotics, Science, Technology, thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GT Interdisciplinary studies::GTD Semiotics / semiology, thema EDItEUR::N History and Archaeology::NH History, thema EDItEUR::P Mathematics and Science::PD Science: general issues::PDR Impact of science and technology on society
Abstract

The 43rd UID conference, held in Genova, takes up the theme of ‘Dialogues’ as practice and debate on many fundamental topics in our social life, especially in these complex and not yet resolved times. The city of Genova offers the opportunity to ponder on the value of comparison and on the possibilities for the community, naturally focused on the aspects that concern us, as professors, researchers, disseminators of knowledge, or on all the possibile meanings of the discipline of representation and its dialogue with ‘others’, which we have broadly catalogued in three macro areas: History, Semiotics, Science / Technology. Therefore, “dialogue” as a profitable exchange based on a common language, without which it is impossible to comprehend and understand one another; and the graphic sign that connotes the conference is the precise transcription of this concept: the title ‘translated’ into signs, derived from the visual alphabet designed for the visual identity of the UID since 2017. There are many topics which refer to three macro sessions: - Witnessing (signs and history) - Communicating (signs and semiotics) - Experimenting (signs and sciences) Thanks to the different points of view, an exceptional resource of our disciplinary area, we want to try to outline the prevailing theoretical-operational synergies, the collaborative lines of an instrumental nature, the recent updates of the repertoires of images that attest and nourish the relations among representation, history, semiotics, sciences.

Published
2022
Full Text
View/download PDF

2. Mitochondrial DNA control-region and coding-region data highlight geographically structured diversity and post-domestication population dynamics in worldwide donkeys.

Author

Rambaldi Migliore, Nicola, Bigi, Daniele, Milanesi, Marco, Zambonelli, Paolo, Negrini, Riccardo, Morabito, Simone, Verini-Supplizi, Andrea, Liotta, Luigi, Chegdani, Fatima, Agha, Saif, Salim, Bashir, Beja-Pereira, Albano, Torroni, Antonio, Ajmone‐Marsan, Paolo, Achilli, Alessandro, and Colli, Licia

Subjects
*MITOCHONDRIAL DNA, *HAPLOGROUPS, *POPULATION dynamics, *EQUUS, *DONKEYS, DEVELOPED countries
Abstract

Donkeys (Equus asinus) have been used extensively in agriculture and transportations since their domestication, ca. 5000–7000 years ago, but the increased mechanization of the last century has largely spoiled their role as burden animals, particularly in developed countries. Consequently, donkey breeds and population sizes have been declining for decades, and the diversity contributed by autochthonous gene pools has been eroded. Here, we examined coding-region data extracted from 164 complete mitogenomes and 1392 donkey mitochondrial DNA (mtDNA) control-region sequences to (i) assess worldwide diversity, (ii) evaluate geographical patterns of variation, and (iii) provide a new nomenclature of mtDNA haplogroups. The topology of the Maximum Parsimony tree confirmed the two previously identified major clades, i.e. Clades 1 and 2, but also highlighted the occurrence of a deep-diverging lineage within Clade 2 that left a marginal trace in modern donkeys. Thanks to the identification of stable and highly diagnostic coding-region mutational motifs, the two lineages were renamed as haplogroup A and haplogroup B, respectively, to harmonize clade nomenclature with the standard currently adopted for other livestock species. Control-region diversity and population expansion metrics varied considerably between geographical areas but confirmed North-eastern Africa as the likely domestication center. The patterns of geographical distribution of variation analyzed through phylogenetic networks and AMOVA confirmed the co-occurrence of both haplogroups in all sampled populations, while differences at the regional level point to the joint effects of demography, past human migrations and trade following the spread of donkeys out of the domestication center. Despite the strong decline that donkey populations have undergone for decades in many areas of the world, the sizeable mtDNA variability we scored, and the possible identification of a new early radiating lineage further stress the need for an extensive and large-scale characterization of donkey nuclear genome diversity to identify hotspots of variation and aid the conservation of local breeds worldwide. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

5. Selection Signatures in Italian Livestock Guardian and Herding Shepherd Dogs.

Author

Bionda, Arianna, Cortellari, Matteo, Bigi, Daniele, Chiofalo, Vincenzo, Liotta, Luigi, and Crepaldi, Paola

Subjects
LIVESTOCK protection dogs, DOGS, DOG breeds, HERDING, MUSCLE growth, DOG behavior, PHENOTYPES
Abstract

Simple Summary: Livestock guardian and herding shepherd dogs are morphologically and behaviourally different, due to the long selection for different tasks made by farmers and breeders. This study aimed to identify genomic regions that best distinguish and characterise four livestock guardian and five herding Italian dog breeds. Genomic SNP data of 158 dogs were compared using two analyses, allowing for the identification of regions harbouring 29 genes. Sixteen runs of homozygosity islands were found in livestock guardians, four of which were partially shared with the fifteen found in herding shepherd dogs. The identified genes were related to dog domestication and behaviour, including herding behaviour, body size and muscle development, the prick or drop ear phenotype, and eye development and functionality. These results contribute to a better understanding of how human selection shaped the genome of dogs selected for different tasks, even considering a limited geographic area. Livestock guardian (LGD) and herding shepherd (HSD) dogs have distinct morphological and behavioural characteristics, long selected by farmers and breeders, to accomplish different tasks. This study aimed to find the genomic regions that best differentiate and characterise Italian LGD and HSD. Genomic data of 158 dogs of four LGD and five HSD breeds, obtained with the 170K canine SNPchip, were collected. The two groups were compared using FST and XP-EHH analyses, identifying regions containing 29 genes. Moreover, 16 islands of runs of homozygosity were found in LGD, and 15 in HSD; 4 of them were partially shared. Among the genes found that better differentiated HSD and LGD, several were associated with dog domestication and behavioural aspects; particularly, MSRB3 and LLPH were linked to herding behaviour in previous studies. Others, DYSK, MAP2K5, and RYR, were related to body size and muscle development. Prick ears prevailed in sampled HSD, and drop ears in LGD; this explains the identification of WIF1 and MSRB3 genes. Unexpectedly, a number of genes were also associated with eye development and functionality. These results shed further light on the differences that human selection introduced in dogs aimed at different duties, even in a limited geographic area such as Italy. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

7. Analysis of Polycerate Mutants Reveals the Evolutionary Co-option of HOXD1 for Horn Patterning in Bovidae

Author

Allais-Bonnet, Aurélie, Hintermann, Aurélie, Deloche, Marie-Christine, Cornette, Raphaël, Bardou, Philippe, Naval-Sanchez, Marina, Pinton, Alain, Haruda, Ashleigh, Grohs, Cécile, Zakany, Jozsef, Bigi, Daniele, Medugorac, Ivica, Putelat, Olivier, Greyvenstein, Ockert, Hadfield, Tracy, Jemaa, Slim Ben, Bunevski, Gjoko, Menzi, Fiona, Hirter, Nathalie, Paris, Julia M, Hedges, John, Palhiere, Isabelle, Rupp, Rachel, Lenstra, Johannes A, Gidney, Louisa, Lesur, Joséphine, Schafberg, Renate, Stache, Michael, Wandhammer, Marie-Dominique, Arbogast, Rose-Marie, Guintard, Claude, Blin, Amandine, Boukadiri, Abdelhak, Rivière, Julie, Esquerré, Diane, Donnadieu, Cécile, Danchin-Burge, Coralie, Reich, Coralie M, Riley, David G, van Marle-Koster, Este, Cockett, Noelle, Hayes, Benjamin J, Drögemüller, Cord, Kijas, James, Pailhoux, Eric, Tosser-Klopp, Gwenola, Duboule, Denis, Capitan, Aurélien, Allais-Bonnet, Aurélie, Hintermann, Aurélie, Deloche, Marie-Christine, Cornette, Raphaël, Bardou, Philippe, Naval-Sanchez, Marina, Pinton, Alain, Haruda, Ashleigh, Grohs, Cécile, Zakany, Jozsef, Bigi, Daniele, Medugorac, Ivica, Putelat, Olivier, Greyvenstein, Ockert, Hadfield, Tracy, Jemaa, Slim Ben, Bunevski, Gjoko, Menzi, Fiona, Hirter, Nathalie, Paris, Julia M, Hedges, John, Palhiere, Isabelle, Rupp, Rachel, Lenstra, Johannes A, Gidney, Louisa, Lesur, Joséphine, Schafberg, Renate, Stache, Michael, Wandhammer, Marie-Dominique, Arbogast, Rose-Marie, Guintard, Claude, Blin, Amandine, Boukadiri, Abdelhak, Rivière, Julie, Esquerré, Diane, Donnadieu, Cécile, Danchin-Burge, Coralie, Reich, Coralie M, Riley, David G, van Marle-Koster, Este, Cockett, Noelle, Hayes, Benjamin J, Drögemüller, Cord, Kijas, James, Pailhoux, Eric, Tosser-Klopp, Gwenola, Duboule, Denis, and Capitan, Aurélien

Published
2021

8. Analysis of Polycerate Mutants Reveals the Evolutionary Co-option of HOXD1 for Horn Patterning in Bovidae

Author

Allais-Bonnet, Aurélie, primary, Hintermann, Aurélie, additional, Deloche, Marie-Christine, additional, Cornette, Raphaël, additional, Bardou, Philippe, additional, Naval-Sanchez, Marina, additional, Pinton, Alain, additional, Haruda, Ashleigh, additional, Grohs, Cécile, additional, Zakany, Jozsef, additional, Bigi, Daniele, additional, Medugorac, Ivica, additional, Putelat, Olivier, additional, Greyvenstein, Ockert, additional, Hadfield, Tracy, additional, Jemaa, Slim Ben, additional, Bunevski, Gjoko, additional, Menzi, Fiona, additional, Hirter, Nathalie, additional, Paris, Julia M, additional, Hedges, John, additional, Palhiere, Isabelle, additional, Rupp, Rachel, additional, Lenstra, Johannes A, additional, Gidney, Louisa, additional, Lesur, Joséphine, additional, Schafberg, Renate, additional, Stache, Michael, additional, Wandhammer, Marie-Dominique, additional, Arbogast, Rose-Marie, additional, Guintard, Claude, additional, Blin, Amandine, additional, Boukadiri, Abdelhak, additional, Rivière, Julie, additional, Esquerré, Diane, additional, Donnadieu, Cécile, additional, Danchin-Burge, Coralie, additional, Reich, Coralie M, additional, Riley, David G, additional, Marle-Koster, Este van, additional, Cockett, Noelle, additional, Hayes, Benjamin J, additional, Drögemüller, Cord, additional, Kijas, James, additional, Pailhoux, Eric, additional, Tosser-Klopp, Gwenola, additional, Duboule, Denis, additional, and Capitan, Aurélien, additional

Published
2021
Full Text
View/download PDF

10. Design and development of a multiplex microsatellite panel for the genetic characterisation and diversity assessment of domestic turkey (Meleagris gallopavo gallopavo)

Author

Canales Vergara, Amado Manuel, primary, Landi, Vincenzo, additional, Delgado Bermejo, Juan Vicente, additional, Martínez, Amparo Martínez, additional, Cervantes Acosta, Patricia, additional, Pons Barros, Agueda, additional, Bigi, Daniele, additional, Sponenberg, Phillip, additional, Helal, Mostafa, additional, Banabazi, Mohammad Hossein, additional, and Camacho Vallejo, Maria Esperanza, additional

Published
2020
Full Text
View/download PDF

11. Evoluzione di un linguaggio nella progettazione architettonica tra Roma, Tivoli e Ostia in età adrianea

Author

Bigi, Daniele

Subjects
età adrianea, progettazione architettonica, Ostia Antica, architettura romana, Villa Adriana, opus testaceum, Caseggiato del Serapide, II secolo d.C, architettura abitativa, architettura abitativa, piena età imperiale, villa adriana, ostia, composizione architettonica, età adrianea, II secolo d.C, composizione architettonica, piena età imperiale, ostia
Published
2020

12. The GENETPIG database: a tool for comparative mapping in pig (Sus scrofa)

Author

Karsenty, Emmanuelle, Barillot, Emmanuel, Tosser-Klopp, Gwenola, Lahbib-Mansais, Yvette, Milan, Denis, Hatey, François, Cirera, Susanna, Sawera, Milena, Jørgensen, Claus B., Chowdhary, Bhanu, Fredholm, Merete, Wimmers, Klaus, Ponsuksili, Siriluck, Davoli, Roberta, Fontanesi, Luca, Braglia, Silvia, Zambonelli, Paolo, Bigi, Daniele, Neuenschwander, Stefan, and Gellin, Joël

Published
2003

13. Tracing Worldwide Turkey Genetic Diversity Using D-loop Sequence Mitochondrial DNA Analysis

Author

Canales Vergara, Amado Manuel, primary, Landi, Vincenzo, additional, Delgado Bermejo, Juan Vicente, additional, Martínez, Amparo, additional, Cervantes Acosta, Patricia, additional, Pons Barro, Águeda, additional, Bigi, Daniele, additional, Sponenberg, Phillip, additional, Helal, Mostafa, additional, Hossein Banabazi, Mohammad, additional, and Camacho Vallejo, María Esperanza, additional

Published
2019
Full Text
View/download PDF

14. Tracing Worldwide Turkey Genetic Diversity Using D-loop Sequence Mitochondrial DNA Analysis

Author

Canales Vergara, Amado Manuel, Landi, Vincenzo, Delgado Bermejo, Juan Vicente, Martínez, Amparo, Cervantes Acosta, Patricia, Pons Barro, Águeda, Bigi, Daniele, Sponenberg, D. Phillip, Helal, Mostafa, Hossein Banabazi, Mohammad, Camacho Vallejo, María Esperanza, Canales Vergara, Amado Manuel, Landi, Vincenzo, Delgado Bermejo, Juan Vicente, Martínez, Amparo, Cervantes Acosta, Patricia, Pons Barro, Águeda, Bigi, Daniele, Sponenberg, D. Phillip, Helal, Mostafa, Hossein Banabazi, Mohammad, and Camacho Vallejo, María Esperanza

Abstract

According to recent archeological evidence, turkey (Meleagris gallopavo gallopavo) domestication may have occurred in Mexico around 2000 years ago. However, little is known about the phylogenetic and genealogical background underlying domestic turkey populations. This study aimed to further understand the domestication process and identify inter- or intraspecific connections between turkey populations to determine their origins, trace their global expansion, and define the species’ genetic value. Ninety-three domestic turkeys (local breeds) were sampled from populations in Brazil, Mexico, USA, Spain, Italy, Iran, and Egypt. Publicly available sequences from previous studies were also included. Standard mitochondrial DNA, genetic diversity, and haplotype network analyses were performed. Seventy-six polymorphic sites were identified. Turkeys from Mexico showed the greatest number of polymorphic sites (40), while turkeys from Italy and Brazil reported only one site each. Nucleotide diversity was also highest in Mexico and the USA (π = 0.0175 and 0.0102, respectively) and lowest in Brazil and Italy. Of the six major haplogroups defined, the Mexican and USA populations appeared to have remained more stable and diverse than the other populations. This may be due to conservative husbandry policies in the rural areas of other populations, which have prevented the introduction of commercial turkey lines.

Published
2019
Full Text
View/download PDF

15. Museo

Author

Bigi, Daniele

Subjects
Canopo, museo, Villa Adriana, porticus a pilastri
Published
2018

16. Caserma dei Vigili

Author

Bigi, Daniele

Subjects
Caserma dei Vigili, Villa Adriana, architettura non imperiale
Published
2018

17. Hospitalia

Author

Bigi, Daniele

Subjects
hospitalia, cubicula, villa adriana
Published
2018

18. Triclinio Imperiale

Author

Bigi, Daniele

Subjects
triclinio imperiale, villa adriana
Published
2018

19. Studies of modern Italian dog populations reveal multiple patterns for domestic breed evolution

Author

Talenti, Andrea, primary, Dreger, Dayna L., additional, Frattini, Stefano, additional, Polli, Michele, additional, Marelli, Stefano, additional, Harris, Alexander C., additional, Liotta, Luigi, additional, Cocco, Raffaella, additional, Hogan, Andrew N., additional, Bigi, Daniele, additional, Caniglia, Romolo, additional, Parker, Heidi G., additional, Pagnacco, Giulio, additional, Ostrander, Elaine A., additional, and Crepaldi, Paola, additional

Published
2018
Full Text
View/download PDF

23. The GENETPIG database: a tool for comparative mapping in pig (Sus scrofa)

Author

Karsenty, Emmanuelle, Barillot, Emmanuel, Tosser-Klopp, Gwenola, Lahbib-Mansais, Yvette, Milan, Denis, Hatey, François, Cirera, Susanna, Sawera, Milena, Jørgensen, Claus B., Chowdhary, Bhanu, Fredholm, Merete, Wimmers, Klaus, Ponsuksili, Siriluck, Davoli, Roberta, Fontanesi, Luca, Braglia, Silvia, Zambonelli, Paolo, Bigi, Daniele, Neuenschwander, Stefan, Gellin, Joël, Karsenty, Emmanuelle, Barillot, Emmanuel, Tosser-Klopp, Gwenola, Lahbib-Mansais, Yvette, Milan, Denis, Hatey, François, Cirera, Susanna, Sawera, Milena, Jørgensen, Claus B., Chowdhary, Bhanu, Fredholm, Merete, Wimmers, Klaus, Ponsuksili, Siriluck, Davoli, Roberta, Fontanesi, Luca, Braglia, Silvia, Zambonelli, Paolo, Bigi, Daniele, Neuenschwander, Stefan, and Gellin, Joël

Abstract

The GENETPIG database has been established for storing and disseminating the results of the European project: ‘GENETPIG: identification of genes controlling economic traits in pig'. The partners of this project have mapped about 630 porcine and human ESTs onto the pig genome. The database collects the mapping results and links them to other sources of mapping data; this includes pig maps as well as available comparative mapping information. Functional annotation of the mapped ESTs is also given when a significant similarity to cognate genes was established. The database is accessible for consultation via the Internet at http://www.infobiogen.fr/services/Genetpig

Published
2017

24. Analysis of ddRAD-seq data provides new insights into the genomic structure and patterns of diversity in Italian donkey populations

Author

Criscione, Andrea, Chessari, Giorgio, Cesarani, Alberto, Ablondi, Michela, Asti, Vittoria, Bigi, Daniele, Bordonaro, Salvatore, Ciampolini, Roberta, Cipolat-Gotet, Claudio, Congiu, Michele, De Palo, Pasquale, Landi, Vincenzo, Macciotta, Nicolò Pietro Paolo, Matassino, Donato, Portolano, Baldassare, Riggio, Silvia, Sabbioni, Alberto, Sardina, Maria Teresa, Senczuk, Gabriele, Tumino, Serena, Vasini, Matteo, Ciani, Elena, and Mastrangelo, Salvatore

Abstract

With more than 150 recognized breeds, donkeys assume relevant economic importance, especially in developing countries. Even if the estimated number of heads worldwide is 53M, this species received less attention than other livestock species. Italy has traditionally been considered one of the cradles of European donkey breeding, and despite a considerable loss of biodiversity, today still counts nine autochthonous populations. A total of 220 animals belonging to nine different populations were genotyped using the double-digest restriction site associated DNA (ddRAD) sequencing to investigate the pattern of diversity using a multi-technique approach. A total of 418,602,730 reads were generated and successfully demultiplexed to obtain a medium-density SNP genotypes panel with about 27K markers. The diversity indices showed moderate levels of variability. The genetic distances and relationships, largely agree with the breeding history of the donkey populations under investigation. The results highlighted the separation of populations based on their genetic origin or geographical proximity between breeding areas, showed low to moderate levels of admixture, and indicated a clear genetic difference in some cases. For some breeds, the results also validate the success of proper management conservation plans. Identified runs of homozygosity islands, mapped within genomic regions related to immune response and local adaptation, are consistent with the characteristics of the species known for its rusticity and adaptability. This study is the first exhaustive genome-wide analysis of the diversity of Italian donkey populations. The results emphasized the high informativeness of genome-wide markers retrieved through the ddRAD approach. The findings take on great significance in designing and implementing conservation strategies. Standardized genotype arrays for donkey species would make it possible to combine worldwide datasets to provide further insights into the evolution of the genomic structure and origin of this important genetic resource.This is the first study deciphering the genetic structure of Italian donkey populations using SNP data. The results of this study confirmed the history of the investigated populations in terms of both genetic and geographical origins.Donkeys assume relevant economic importance in several countries worldwide. However, the genetic structure of these populations is less investigated compared to other species. The aim of this study was to investigate the genetic background of nine different Italian donkey populations. A total of 220 animals were genotyped with about 27K markers extracted by the double-digest restriction site associated DNA sequencing. The consistency of the results across different approaches agreed with the demographic history, the origin, and previous results on the nine donkey populations, suggesting that our conclusions are robust. Moreover, the results of the present study highlighted low to moderate levels of admixture and, for some breeds, confirmed the success of proper management conservation plans.

Published
2024
Full Text
View/download PDF

26. Multilocus Detection of Wolf x Dog Hybridization in Italy, and Guidelines for Marker Selection.

Author

Randi, Ettore, Hulva, Pavel, Fabbri, Elena, Galaverni, Marco, Galov, Ana, Kusak, Josip, Bigi, Daniele, Bolfíková, Barbora Černá, Smetanová, Milena, and Caniglia, Romolo

Subjects
WOLFDOGS, DOG breeding, BIOMARKERS, ENDANGERED species, MITOCHONDRIAL DNA, Y chromosome
Abstract

Hybridization and introgression can impact the evolution of natural populations. Several wild canid species hybridize in nature, sometimes originating new taxa. However, hybridization with free-ranging dogs is threatening the genetic integrity of grey wolf populations (Canis lupus), or even the survival of endangered species (e.g., the Ethiopian wolf C. simensis). Efficient molecular tools to assess hybridization rates are essential in wolf conservation strategies. We evaluated the power of biparental and uniparental markers (39 autosomal and 4 Y-linked microsatellites, a melanistic deletion at the β-defensin CBD103 gene, the hypervariable domain of the mtDNA control-region) to identify the multilocus admixture patterns in wolf x dog hybrids. We used empirical data from 2 hybrid groups with different histories: 30 presumptive natural hybrids from Italy and 73 Czechoslovakian wolfdogs of known hybrid origin, as well as simulated data. We assessed the efficiency of various marker combinations and reference samples in admixture analyses using 69 dogs of different breeds and 99 wolves from Italy, Balkans and Carpathian Mountains. Results confirmed the occurrence of hybrids in Italy, some of them showing anomalous phenotypic traits and exogenous mtDNA or Y-chromosome introgression. Hybridization was mostly attributable to village dogs and not strictly patrilineal. The melanistic β-defensin deletion was found only in Italian dogs and in putative hybrids. The 24 most divergent microsatellites (largest wolf-dog FST values) were equally or more informative than the entire panel of 39 loci. A smaller panel of 12 microsatellites increased risks to identify false admixed individuals. The frequency of F1 and F2 was lower than backcrosses or introgressed individuals, suggesting hybridization already occurred some generations in the past, during early phases of wolf expansion from their historical core areas. Empirical and simulated data indicated the identification of the past generation backcrosses is always uncertain, and a larger number of ancestry-informative markers is needed. [ABSTRACT FROM AUTHOR]

Published
2014
Full Text
View/download PDF

27. The GENETPIG database: a tool for comparative mapping in pig (Sus scrofa)

Author

Karsenty, Emmanuelle, Barillot, Emmanuel, Tosser-Klopp, Gwenola, Lahbib-Mansais, Yvette, Milan, Denis, Hatey, François, Cirera, Susanna, Sawera, Milena, Jørgensen, Claus B., Chowdhary, Bhanu, Fredholm, Merete, Wimmers, Klaus, Ponsuksili, Siriluck, Davoli, Roberta, Fontanesi, Luca, Braglia, Silvia, Zambonelli, Paolo, Bigi, Daniele, Neuenschwander, Stefan, Gellin, Joël, Karsenty, Emmanuelle, Barillot, Emmanuel, Tosser-Klopp, Gwenola, Lahbib-Mansais, Yvette, Milan, Denis, Hatey, François, Cirera, Susanna, Sawera, Milena, Jørgensen, Claus B., Chowdhary, Bhanu, Fredholm, Merete, Wimmers, Klaus, Ponsuksili, Siriluck, Davoli, Roberta, Fontanesi, Luca, Braglia, Silvia, Zambonelli, Paolo, Bigi, Daniele, Neuenschwander, Stefan, and Gellin, Joël

Abstract

The GENETPIG database has been established for storing and disseminating the results of the European project: ‘GENETPIG: identification of genes controlling economic traits in pig'. The partners of this project have mapped about 630 porcine and human ESTs onto the pig genome. The database collects the mapping results and links them to other sources of mapping data; this includes pig maps as well as available comparative mapping information. Functional annotation of the mapped ESTs is also given when a significant similarity to cognate genes was established. The database is accessible for consultation via the Internet at http://www.infobiogen.fr/services/Genetpig

28. Analysis of Polycerate Mutants Reveals the Evolutionary Co-option of HOXD1 for Horn Patterning in Bovidae

Author

Daniele Bigi, Fiona Menzi, Slim Ben Jemaa, Marie-Christine Deloche, Aurélien Capitan, Johannes A. Lenstra, Marina Naval-Sanchez, Ivica Medugorac, Nathalie Hirter, Gwenola Tosser-Klopp, Diane Esquerre, Coralie M. Reich, Julia M. Paris, Rose-Marie Arbogast, Amandine Blin, Abdelhak Boukadiri, Aurélie Hintermann, Julie Rivière, Denis Duboule, Raphaël Cornette, Cécile Donnadieu, Marie-Dominique Wandhammer, Gjoko Bunevski, Louisa Gidney, Michael Stache, Isabelle Palhiere, Renate Schafberg, James Kijas, Claude Guintard, Joséphine Lesur, Jozsef Zakany, Rachel Rupp, Noelle E. Cockett, John Hedges, Ashleigh Haruda, Philippe Bardou, Olivier Putelat, Tracy Hadfield, Alain Pinton, Ockert Greyvenstein, Aurélie Allais-Bonnet, Este Van Marle-Koster, Eric Pailhoux, Coralie Danchin-Burge, David G. Riley, Cécile Grohs, Benjamin J. Hayes, Cord Drögemüller, Allice, Biologie de la Reproduction, Environnement, Epigénétique & Développement (BREED), Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-École nationale vétérinaire d'Alfort (ENVA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Institut de Systématique, Evolution, Biodiversité (ISYEB ), Muséum national d'Histoire naturelle (MNHN)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université des Antilles (UA), Génétique Physiologie et Systèmes d'Elevage (GenPhySE ), Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-École nationale supérieure agronomique de Toulouse [ENSAT]-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Commonwealth Scientific and Industrial Research Organisation [Canberra] (CSIRO), École nationale supérieure agronomique de Toulouse [ENSAT]-Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Martin-Luther-University Halle-Wittenberg, Génétique Animale et Biologie Intégrative (GABI), Université Paris-Saclay-AgroParisTech-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), University of Geneva [Switzerland], University of Bologna, Ludwig Maximilian University [Munich] (LMU), Archéologie d'Alsace, Archéologie et histoire ancienne : Méditerranée - Europe (ARCHIMEDE), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Ministère de la Culture et de la Communication (MCC)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA), Texas A&M University [College Station], Utah State University (USU), Université de Carthage - University of Carthage, Ss. Cyril and Methodius University in Skopje, University of Bern, Manx Text, Manx Loaghtan Sheep Breeders (MLSBG), Utrecht University [Utrecht], Rent a Peasant, Archéozoologie, archéobotanique : sociétés, pratiques et environnements (AASPE), Muséum national d'Histoire naturelle (MNHN)-Centre National de la Recherche Scientifique (CNRS), Musée Zoologique de Strasbourg, Ecole Nationale Vétérinaire, Agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS), Acquisition et Analyse de Données pour l'Histoire naturelle (2AD), MICrobiologie de l'ALImentation au Service de la Santé (MICALIS), AgroParisTech-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Génome et Transcriptome - Plateforme Génomique ( GeT-PlaGe), Plateforme Génome & Transcriptome (GET), Génopole Toulouse Midi-Pyrénées [Auzeville] (GENOTOUL), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Génopole Toulouse Midi-Pyrénées [Auzeville] (GENOTOUL), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut de l'élevage (IDELE), Agriculture Victoria (AgriBio), Tshwane University of Technology [Pretoria] (TUT), Queensland Alliance for Agriculture and Food Innovation (QAAFI), University of Queensland [Brisbane], CSIRO Agriculture and Food (CSIRO), Ecole Polytechnique Fédérale de Lausanne (EPFL), Collège de France (CdF (institution)), Allais-Bonnet, Aurélie, Hintermann, Aurélie, Deloche, Marie-Christine, Cornette, Raphaël, Bardou, Philippe, Naval-Sanchez, Marina, Pinton, Alain, Haruda, Ashleigh, Grohs, Cécile, Zakany, Jozsef, Bigi, Daniele, Medugorac, Ivica, Putelat, Olivier, Greyvenstein, Ockert, Hadfield, Tracy, Jemaa, Slim Ben, Bunevski, Gjoko, Menzi, Fiona, Hirter, Nathalie, Paris, Julia M, Hedges, John, Palhiere, Isabelle, Rupp, Rachel, Lenstra, Johannes A, Gidney, Louisa, Lesur, Joséphine, Schafberg, Renate, Stache, Michael, Wandhammer, Marie-Dominique, Arbogast, Rose-Marie, Guintard, Claude, Blin, Amandine, Boukadiri, Abdelhak, Rivière, Julie, Esquerré, Diane, Donnadieu, Cécile, Danchin-Burge, Coralie, Reich, Coralie M, Riley, David G, Marle-Koster, Este van, Cockett, Noelle, Hayes, Benjamin J, Drögemüller, Cord, Kijas, Jame, Pailhoux, Eric, Tosser-Klopp, Gwenola, Duboule, Deni, Capitan, Aurélien, École nationale vétérinaire d'Alfort (ENVA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Ministère de la Culture et de la Communication (MCC)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Muséum national d'Histoire naturelle (MNHN), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), École nationale vétérinaire - Alfort (ENVA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-École nationale supérieure agronomique de Toulouse [ENSAT], Université de Genève = University of Geneva (UNIGE), University of Bologna/Università di Bologna, Ss. Cyril and Methodius University in Skopje (UKIM), École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS), and Collège de France - Chaire internationale Évolution des génomes et développement

Subjects
0106 biological sciences, Male, co-option, translocation, AcademicSubjects/SCI01180, regulatory mutation, 01 natural sciences, Hox genes, Hox gene, genes, 610 Medicine & health, Bilateria, time, Horns, 0303 health sciences, biology, Ecology, 630 Agriculture, Goats, [SDV.BDD.EO] Life Sciences [q-bio]/Development Biology/Embryology and Organogenesis, Gene Expression Regulation, Developmental, alignment, Morphogenetic field, Biological Evolution, [SDV.BDD.MOR] Life Sciences [q-bio]/Development Biology/Morphogenesis, 590 Animals (Zoology), Haploinsufficiency, transcription, Biometry, Evolution, growth, Locus (genetics), Mice, Transgenic, [SDV.GEN.GA] Life Sciences [q-bio]/Genetics/Animal genetics, 010603 evolutionary biology, 03 medical and health sciences, goat and sheep genomics, Behavior and Systematics, framework, Genetics, Animals, Allele, Gene, Molecular Biology, Discoveries, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Homeodomain Proteins, locus, Sheep, Horn (anatomy), AcademicSubjects/SCI01130, [SDV.BDD.MOR]Life Sciences [q-bio]/Development Biology/Morphogenesis, sequence, biology.organism_classification, [SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal genetics, [SDV.BDD.EO]Life Sciences [q-bio]/Development Biology/Embryology and Organogenesis, Evolutionary biology, Mutation, genome-wide association, 570 Life sciences, goat and sheep genomic
Abstract

In the course of evolution, pecorans (i.e., higher ruminants) developed a remarkable diversity of osseous cranial appendages, collectively referred to as “headgear,” which likely share the same origin and genetic basis. However, the nature and function of the genetic determinants underlying their number and position remain elusive. Jacob and other rare populations of sheep and goats are characterized by polyceraty, the presence of more than two horns. Here, we characterize distinct POLYCERATE alleles in each species, both associated with defective HOXD1 function. We show that haploinsufficiency at this locus results in the splitting of horn bud primordia, likely following the abnormal extension of an initial morphogenetic field. These results highlight the key role played by this gene in headgear patterning and illustrate the evolutionary co-option of a gene involved in the early development of bilateria to properly fix the position and number of these distinctive organs of Bovidae.

Published
2021
Full Text
View/download PDF

29. Lamb meat traceability: The case of Sambucana sheep

Author

Alfredo Pauciullo, Liliana Di Stasio, Emiliano Lasagna, Daniele Bigi, Piergiovanni Piatti, Edoardo Fontanella, Stefano Costa, Di Stasio, Liliana, Piatti, Piergiovanni, Fontanella, Edoardo, Testa, Stefano, Bigi, Daniele, Lasagna, Emiliano, and Pauciullo, Alfredo

Subjects
0106 biological sciences, Meat, Sheep, Traceability, Computer science, business.industry, Genetic traceability, 0402 animal and dairy science, 04 agricultural and veterinary sciences, Certification, Registered trademark, 040201 dairy & animal science, 010603 evolutionary biology, 01 natural sciences, Biotechnology, Product certification, Food Animals, Genetic traceability, Meat, Sheep, Sambucana breed, Animal Science and Zoology, Sambucana breed, business
Abstract

Genetic traceability has a key role in the product certification, but it is rarely implemented in sheep so far, especially in the fresh meat sector. In this study, the case of the Sambucana sheep is analysed with the aim of developing a genetic system able to certify the origin of its traditional product, the Sambucano lamb, protected by a registered trademark. A set of 14 microsatellite markers was identified as an efficient tool to genetically discriminate the Sambucana sheep from other breeds potentially involved in mislabelling and to allow for an effective allocation test of meat cuts labelled as ‘Guaranteed Sambucano lamb’. The paternity test proved to be an additional means to improve the reliability of the control. The traceability system here described is easy to implement in local minor sheep breeds and is recommended in the framework of meat certification.

Published
2017

30. Assessment of ante mortem welfare indicators and the pathophysiology of captive-bolt trauma in equids at slaughter.

Author

Fletcher KA, Padalino B, Felici M, Bigi D, Limon-Vega G, Grist A, and Gibson TJ

Abstract

There is limited research into horse slaughter, particularly ante mortem welfare, and the effectiveness of captive-bolt gun (CBG) stunning, despite this being a widely used method worldwide. To address this evidence gap and explore associations between ante and post mortem factors, the welfare of 62 horses was assessed at a commercial Italian abattoir. Animal-based measures were used to identify stress-related behaviours and stunning effectiveness. A sub-sample (44%; 27/62) of heads were assessed for gross brain pathology. All animals in the study showed stress-related behaviours at all stages of the slaughter process. Additionally, 53% (33/62) of horses slipped in the stunning box, with poor floor surface condition and use of force associated with this. At least one sign of an ineffective stun was observed in 22% (14/62) of animals. Six animals were shot twice, with the application of a second shot significantly associated with a higher stress behaviour index score in the stunning box. Damage to critical brainstem structures was found in 85% (23/27) of heads that were assessed with gross pathology. An absence of damage to critical brainstem structures meant that animals were ten times more likely to show signs of ineffective stunning. These results highlight the risks to equine welfare throughout the slaughter process and suggest that mitigating ante mortem stress could improve stunning effectiveness, whilst CBG usage should be refined to ensure that critical brainstem structures are targeted., Competing Interests: None., (© The Author(s) 2025.)

Published
2025
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results