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1. The 2023 Dengue Outbreak in Lombardy, Italy: A One-Health Perspective

Author

Rovida, Francesca, Faccini, Marino, Grané, Carla Molina, Cassaniti, Irene, Senatore, Sabrina, Rossetti, Eva, Scardina, Giuditta, Piazza, Manuela, Campanini, Giulia, Lilleri, Daniele, Paolucci, Stefania, Ferrari, Guglielmo, Piralla, Antonio, Defilippo, Francesco, Lelli, Davide, Moreno, Ana, Vezzosi, Luigi, Attanasi, Federica, Marzia, Soresini, Manuela, Barozzi, Cerutti, Lorenzo, Paglia, Stefano, Regazzetti, Angelo, Marcacci, Maurilia, Di Donato, Guido, Farioli, Marco, Manica, Mattia, Poletti, Piero, Lavazza, Antonio, Bonini, Maira, Merler, Stefano, Baldanti, Fausto, Cereda, Danilo, and network, Lombardy Dengue

Subjects
Quantitative Biology - Populations and Evolution
Abstract

Introduction. Here we reported the virological, entomological and epidemiological characteristics of the large autochthonous outbreak of dengue (DENV) occurred in a small village of the Lombardy region (Northern Italy) during summer 2023. Methods. After the diagnosis of the first autochthonous case on 18 August 2023, public health measures, including epidemiological investigation and vector control measures, were carried out. A serological screening for DENV antibodies detection was offered to the population. In the case of positive DENV IgM, a second sample was collected to detect DENV RNA and verify seroconversion. Entomological and epidemiological investigations were also performed. A modeling analysis was conducted to estimate the dengue generation time, transmission potential, distance of transmission, and assess diagnostic delays. Results. Overall, 416 subjects participated to the screening program and 20 were identified as DENV-1 cases (15 confirmed and 5 probable). In addition, DENV-1 infection was diagnosed in 24 symptomatic subjects referred to the local Emergency Room Department for suggestive symptoms and 1 case was identified through blood donation screening. The average generation time was estimated to be 18.3 days (95% CI: 13.1-23.5 days). R0 was estimated at 1.31 (95% CI: 0.76-1.98); 90% of transmission occurred within 500m. Entomological investigations performed in 46 pools of mosquitoes revealed the presence of only one positive pool for DENV-1. Discussion. This report highlights the importance of synergic surveillance, including virological, entomological and public health measures to control the spread of arboviral infections.

Published
2024

2. The 2023 dengue outbreak in Lombardy, Italy: A one-health perspective

Author

Sarasini, Antonella, Furione, Milena, Mele, Dalila, Bergami, Federica, Sammartino, Josè Camilla, Ferrari, Alessandro, Romano, Greta, Guglielmo Pitrolo, Antonino Maria, Carrera, Maya, Brugnoli, Rita, Laini, Nunzia, Bonalda, Francesca, Arfani, Sara, Zamboni, Giuditta, Delfanti, Fanny, Ferrari, Piergiuseppe, Dafa, Anxhela, Negri, Antonella, Parisi, Filippa, Tirani, Marcello, Viscardi, Michela, Del Castillo, Gabriele, Morani, Federica, Scovenna, Francesco, Sansebastian, Sheila, Maffeo, Manuel, Chiari, Mario, Tallarita, Enrico, Rovida, Francesca, Faccini, Marino, Molina Granè, Carla, Cassaniti, Irene, Senatore, Sabrina, Rossetti, Eva, Scardina, Giuditta, Piazza, Manuela, Campanini, Giulia, Lilleri, Daniele, Paolucci, Stefania, Ferrari, Guglielmo, Piralla, Antonio, Defilippo, Francesco, Lelli, Davide, Moreno, Ana, Vezzosi, Luigi, Attanasi, Federica, Soresini, Marzia, Barozzi, Manuela, Cerutti, Lorenzo, Paglia, Stefano, Regazzetti, Angelo, Marcacci, Maurilia, Di Donato, Guido, Farioli, Marco, Manica, Mattia, Poletti, Piero, Lavazza, Antonio, Bonini, Maira, Merler, Stefano, Baldanti, Fausto, and Cereda, Danilo

Published
2025
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3. Dynamics of viral DNA shedding and culture viral DNA positivity in different clinical samples collected during the 2022 mpox outbreak in Lombardy, Italy

Author

Cutrera, Miriam, Cuomo, Marianna, De Poli, Federica, Campanini, Giulia, Pitrolo, Antonino Maria Guglielmo, Iskandar, Elizabeth, Cassaniti, Irene, Bruno, Raffaele, Rizzardini, Giuliano, Puoti, Massimo, Castelli, Francesco, Corsico, Laura, Giacomelli, Andrea, Pozza, Giacomo, Casalini, Giacomo, Raccagni, Angelo, Trentacapilli, Bendetta, Bertoni, Costanza, Bruzzesi, Elena, Candela, Caterina, Tesoro, Daniele, Mule, Giovanni, Bandera, Alessandra, Bianca Mariani, Antonio Muscatello, Maffeo, Manuel, Vecchio, Riccardo, Piccinelli, Sara, Piralla, Antonio, Mileto, Davide, Rizzo, Alberto, Ferrari, Guglielmo, Giardina, Federica, Gaiarsa, Stefano, Petazzoni, Greta, Bianchi, Micol, Salari, Federica, Bracchitta, Fiorenza, Sammartino, Josè Camilla, Ferrari, Alessandro, Gagliardi, Gloria, Mancon, Alessandro, Fenizia, Claudio, Biasin, Mara, Rovida, Francesca, Paolucci, Stefania, Percivalle, Elena, Lombardi, Alessandra, Micheli, Valeria, Nozza, Silvia, Castagna, Antonella, Moschese, Davide, Antinori, Spinello, Gori, Andrea, Bonfanti, Paolo, Rossotti, Roberto, D'Arminio Monforte, Antonella, Attanasi, Federica, Tirani, Marcello, Cereda, Danilo, Baldanti, Fausto, and Gismondo, Maria Rita

Published
2024
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4. Dynamics of viral DNA shedding and culture viral DNA positivity in different clinical samples collected during the 2022 mpox outbreak in Lombardy, Italy

Author

Piralla, Antonio, primary, Mileto, Davide, additional, Rizzo, Alberto, additional, Ferrari, Guglielmo, additional, Giardina, Federica, additional, Gaiarsa, Stefano, additional, Petazzoni, Greta, additional, Bianchi, Micol, additional, Salari, Federica, additional, Bracchitta, Fiorenza, additional, Sammartino, Josè Camilla, additional, Ferrari, Alessandro, additional, Gagliardi, Gloria, additional, Mancon, Alessandro, additional, Fenizia, Claudio, additional, Biasin, Mara, additional, Rovida, Francesca, additional, Paolucci, Stefania, additional, Percivalle, Elena, additional, Lombardi, Alessandra, additional, Micheli, Valeria, additional, Nozza, Silvia, additional, Castagna, Antonella, additional, Moschese, Davide, additional, Antinori, Spinello, additional, Gori, Andrea, additional, Bonfanti, Paolo, additional, Rossotti, Roberto, additional, Monforte, Antonella D'arminio, additional, Attanasi, Federica, additional, Tirani, Marcello, additional, Cereda, Danilo, additional, Baldanti, Fausto, additional, Gismondo, Maria Rita, additional, Cutrera, Miriam, additional, Cuomo, Marianna, additional, De Poli, Federica, additional, Campanini, Giulia, additional, Pitrolo, Antonino Maria Guglielmo, additional, Iskandar, Elizabeth, additional, Cassaniti, Irene, additional, Bruno, Raffaele, additional, Rizzardini, Giuliano, additional, Puoti, Massimo, additional, Castelli, Francesco, additional, Corsico, Laura, additional, Giacomelli, Andrea, additional, Pozza, Giacomo, additional, Casalini, Giacomo, additional, Raccagni, Angelo, additional, Trentacapilli, Bendetta, additional, Bertoni, Costanza, additional, Bruzzesi, Elena, additional, Candela, Caterina, additional, Tesoro, Daniele, additional, Mule, Giovanni, additional, Bandera, Alessandra, additional, Bianca Mariani, Antonio Muscatello, additional, Maffeo, Manuel, additional, Vecchio, Riccardo, additional, and Piccinelli, Sara, additional

Published
2024
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5. Surge of Mpox cases in Lombardy region, Italy, October 2023 - January 2024

Author

Moschese, D, Raccagni, A, Giacomelli, A, Piralla, A, Rossotti, R, Raimondi, A, Tesoro, D, Vezzosi, L, Gulletta, M, Clementi, N, Venturelli, S, Benardon, S, Ricaboni, D, Bernacchia, D, Mancon, A, Rovida, F, Attanasi, F, Cereda, D, Gismondo, M, Gori, A, Rizzardini, G, Antinori, S, Baldanti, F, Marzano, A, Marchetti, G, Castelli, F, Castagna, A, Nozza, S, Mileto, D, Bonfanti, P, Biasioli, L, Bruno, R, Vittoria Cossu, M, Fusetti, C, Lazzarin, S, Locatelli, M, Morosi, M, Piscaglia, M, Pusterla, L, Pozza, G, Ramoni, S, Rusconi, S, Rizzi, M, Rizzo, A, Sabaini, F, Salari, F, Sampaolo, M, Puoti, M, Tirani, M, Rachele Tomasoni, L, Moschese, Davide, Raccagni, Angelo Roberto, Giacomelli, Andrea, Piralla, Antonio, Rossotti, Roberto, Raimondi, Alessandro, Tesoro, Daniele, Vezzosi, Luigi, Gulletta, Maurizio, Clementi, Nicola, Venturelli, Serena, Benardon, Susanna, Ricaboni, Davide, Bernacchia, Dario, Mancon, Alessandro, Rovida, Francesca, Attanasi, Federica, Cereda, Danilo, Gismondo, Maria Rita, Gori, Andrea, Rizzardini, Giuliano, Antinori, Spinello, Baldanti, Fausto, Marzano, Angelo Valerio, Marchetti, Giulia, Castelli, Francesco, Castagna, Antonella, Nozza, Silvia, Mileto, Davide, Bonfanti, Paolo, Biasioli, Lorenzo, Bruno, Raffaele, Vittoria Cossu, Maria, Fusetti, Chiara, Lazzarin, Samuel, Locatelli, Massimo, Morosi, Manuela, Piscaglia, Marco, Pusterla, Luigi, Pozza, Giacomo, Ramoni, Stefano, Rusconi, Stefano, Rizzi, Marco, Rizzo, Alberto, Sabaini, Federico, Salari, Federica, Sampaolo, Michela, Puoti, Massimo, Tirani, Marcello, Rachele Tomasoni, Lina, Moschese, D, Raccagni, A, Giacomelli, A, Piralla, A, Rossotti, R, Raimondi, A, Tesoro, D, Vezzosi, L, Gulletta, M, Clementi, N, Venturelli, S, Benardon, S, Ricaboni, D, Bernacchia, D, Mancon, A, Rovida, F, Attanasi, F, Cereda, D, Gismondo, M, Gori, A, Rizzardini, G, Antinori, S, Baldanti, F, Marzano, A, Marchetti, G, Castelli, F, Castagna, A, Nozza, S, Mileto, D, Bonfanti, P, Biasioli, L, Bruno, R, Vittoria Cossu, M, Fusetti, C, Lazzarin, S, Locatelli, M, Morosi, M, Piscaglia, M, Pusterla, L, Pozza, G, Ramoni, S, Rusconi, S, Rizzi, M, Rizzo, A, Sabaini, F, Salari, F, Sampaolo, M, Puoti, M, Tirani, M, Rachele Tomasoni, L, Moschese, Davide, Raccagni, Angelo Roberto, Giacomelli, Andrea, Piralla, Antonio, Rossotti, Roberto, Raimondi, Alessandro, Tesoro, Daniele, Vezzosi, Luigi, Gulletta, Maurizio, Clementi, Nicola, Venturelli, Serena, Benardon, Susanna, Ricaboni, Davide, Bernacchia, Dario, Mancon, Alessandro, Rovida, Francesca, Attanasi, Federica, Cereda, Danilo, Gismondo, Maria Rita, Gori, Andrea, Rizzardini, Giuliano, Antinori, Spinello, Baldanti, Fausto, Marzano, Angelo Valerio, Marchetti, Giulia, Castelli, Francesco, Castagna, Antonella, Nozza, Silvia, Mileto, Davide, Bonfanti, Paolo, Biasioli, Lorenzo, Bruno, Raffaele, Vittoria Cossu, Maria, Fusetti, Chiara, Lazzarin, Samuel, Locatelli, Massimo, Morosi, Manuela, Piscaglia, Marco, Pusterla, Luigi, Pozza, Giacomo, Ramoni, Stefano, Rusconi, Stefano, Rizzi, Marco, Rizzo, Alberto, Sabaini, Federico, Salari, Federica, Sampaolo, Michela, Puoti, Massimo, Tirani, Marcello, and Rachele Tomasoni, Lina

Published
2024

6. Dynamics of viral DNA shedding and culture viral DNA positivity in different clinical samples collected during the 2022 mpox outbreak in Lombardy, Italy

Author

Piralla, A, Mileto, D, Rizzo, A, Ferrari, G, Giardina, F, Gaiarsa, S, Petazzoni, G, Bianchi, M, Salari, F, Bracchitta, F, Sammartino, J, Ferrari, A, Gagliardi, G, Mancon, A, Fenizia, C, Biasin, M, Rovida, F, Paolucci, S, Percivalle, E, Lombardi, A, Micheli, V, Nozza, S, Castagna, A, Moschese, D, Antinori, S, Gori, A, Bonfanti, P, Rossotti, R, Monforte, A, Attanasi, F, Tirani, M, Cereda, D, Baldanti, F, Gismondo, M, Cutrera, M, Cuomo, M, De Poli, F, Campanini, G, Pitrolo, A, Iskandar, E, Cassaniti, I, Bruno, R, Rizzardini, G, Puoti, M, Castelli, F, Corsico, L, Giacomelli, A, Pozza, G, Casalini, G, Raccagni, A, Trentacapilli, B, Bertoni, C, Bruzzesi, E, Candela, C, Tesoro, D, Mule, G, Bandera, A, Bianca Mariani, A, Maffeo, M, Vecchio, R, Piccinelli, S, Piralla, Antonio, Mileto, Davide, Rizzo, Alberto, Ferrari, Guglielmo, Giardina, Federica, Gaiarsa, Stefano, Petazzoni, Greta, Bianchi, Micol, Salari, Federica, Bracchitta, Fiorenza, Sammartino, Josè Camilla, Ferrari, Alessandro, Gagliardi, Gloria, Mancon, Alessandro, Fenizia, Claudio, Biasin, Mara, Rovida, Francesca, Paolucci, Stefania, Percivalle, Elena, Lombardi, Alessandra, Micheli, Valeria, Nozza, Silvia, Castagna, Antonella, Moschese, Davide, Antinori, Spinello, Gori, Andrea, Bonfanti, Paolo, Rossotti, Roberto, Monforte, Antonella D'arminio, Attanasi, Federica, Tirani, Marcello, Cereda, Danilo, Baldanti, Fausto, Gismondo, Maria Rita, Cutrera, Miriam, Cuomo, Marianna, De Poli, Federica, Campanini, Giulia, Pitrolo, Antonino Maria Guglielmo, Iskandar, Elizabeth, Cassaniti, Irene, Bruno, Raffaele, Rizzardini, Giuliano, Puoti, Massimo, Castelli, Francesco, Corsico, Laura, Giacomelli, Andrea, Pozza, Giacomo, Casalini, Giacomo, Raccagni, Angelo, Trentacapilli, Bendetta, Bertoni, Costanza, Bruzzesi, Elena, Candela, Caterina, Tesoro, Daniele, Mule, Giovanni, Bandera, Alessandra, Bianca Mariani, Antonio Muscatello, Maffeo, Manuel, Vecchio, Riccardo, Piccinelli, Sara, Piralla, A, Mileto, D, Rizzo, A, Ferrari, G, Giardina, F, Gaiarsa, S, Petazzoni, G, Bianchi, M, Salari, F, Bracchitta, F, Sammartino, J, Ferrari, A, Gagliardi, G, Mancon, A, Fenizia, C, Biasin, M, Rovida, F, Paolucci, S, Percivalle, E, Lombardi, A, Micheli, V, Nozza, S, Castagna, A, Moschese, D, Antinori, S, Gori, A, Bonfanti, P, Rossotti, R, Monforte, A, Attanasi, F, Tirani, M, Cereda, D, Baldanti, F, Gismondo, M, Cutrera, M, Cuomo, M, De Poli, F, Campanini, G, Pitrolo, A, Iskandar, E, Cassaniti, I, Bruno, R, Rizzardini, G, Puoti, M, Castelli, F, Corsico, L, Giacomelli, A, Pozza, G, Casalini, G, Raccagni, A, Trentacapilli, B, Bertoni, C, Bruzzesi, E, Candela, C, Tesoro, D, Mule, G, Bandera, A, Bianca Mariani, A, Maffeo, M, Vecchio, R, Piccinelli, S, Piralla, Antonio, Mileto, Davide, Rizzo, Alberto, Ferrari, Guglielmo, Giardina, Federica, Gaiarsa, Stefano, Petazzoni, Greta, Bianchi, Micol, Salari, Federica, Bracchitta, Fiorenza, Sammartino, Josè Camilla, Ferrari, Alessandro, Gagliardi, Gloria, Mancon, Alessandro, Fenizia, Claudio, Biasin, Mara, Rovida, Francesca, Paolucci, Stefania, Percivalle, Elena, Lombardi, Alessandra, Micheli, Valeria, Nozza, Silvia, Castagna, Antonella, Moschese, Davide, Antinori, Spinello, Gori, Andrea, Bonfanti, Paolo, Rossotti, Roberto, Monforte, Antonella D'arminio, Attanasi, Federica, Tirani, Marcello, Cereda, Danilo, Baldanti, Fausto, Gismondo, Maria Rita, Cutrera, Miriam, Cuomo, Marianna, De Poli, Federica, Campanini, Giulia, Pitrolo, Antonino Maria Guglielmo, Iskandar, Elizabeth, Cassaniti, Irene, Bruno, Raffaele, Rizzardini, Giuliano, Puoti, Massimo, Castelli, Francesco, Corsico, Laura, Giacomelli, Andrea, Pozza, Giacomo, Casalini, Giacomo, Raccagni, Angelo, Trentacapilli, Bendetta, Bertoni, Costanza, Bruzzesi, Elena, Candela, Caterina, Tesoro, Daniele, Mule, Giovanni, Bandera, Alessandra, Bianca Mariani, Antonio Muscatello, Maffeo, Manuel, Vecchio, Riccardo, and Piccinelli, Sara

Abstract

Background: Mpox virus (MPXV) has recently spread outside of sub-Saharan Africa. This large multicentre study was conducted in Lombardy, the most densely populated Italian region accounting for more than 40% of Italian cases. The present study aims to: i) evaluate the presence and the shedding duration of MPXV DNA in different body compartments correlating the MPXV viability with the time to onset of symptoms; ii) provide evidence of MPXV persistence in different body compartment as a source of infection and iii) characterize the MPXV evolution by whole genome sequencing (WGS) during the outbreak occurred in Italy. Material and methods: The study included 353 patients with a laboratory-confirmed diagnosis of MPXV infection screened in several clinical specimens in the period May 24th - September 1st, 2022. Viral isolation was attempted from different biological matrices and complete genome sequencing was performed for 61 MPXV strains. Results: MPXV DNA detection was more frequent in the skin (94.4%) with the longest median time of viral clearance (16 days). The actively-replicating virus in cell culture was obtained for 123/377 (32.6%) samples with a significant higher viral quantity on isolation positive samples (20 vs 31, p < 0.001). The phylogenetic analysis highlighted the high genetic identity of the MPXV strains collected, both globally and within the Lombardy region. Conclusion: Skin lesion is gold standard material and the high viral load and the actively-replicating virus observed in genital sites confirms that sexual contact plays a key role in the viral transmission.

Published
2024

7. Monkeypox’s management in the lombardy region: data analysis and preparedness for future outbreaks

Author

Sharma, Sudwaric, primary, Vecchio, Riccardo, additional, Piccinelli, Sara, additional, Cicconi, Giovanni, additional, Lattanzio, Roberta, additional, Marrocu, Chiara, additional, Ferraguzzi, Gaia, additional, Attanasi, Federica, additional, Viscardi, Michela, additional, Castaldi, Silvana, additional, Borriello, Catia, additional, and Cereda, Danilo, additional

Published
2023
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10. Outcomes after eye-sparing surgery vs orbital exenteration in patients with lacrimal gland carcinoma

Author

Bita Esmaeli, Piero Donna, Adriana Iuliano, Vincenzo Abbate, Federica Attanasi, Fausto Tranfa, Paola Bonavolontà, Federica Fossataro, Giulio Bonavolontà, Bonavolontà, Paola, Esmaeli, Bita, Donna, Piero, Tranfa, Fausto, Iuliano, Adriana, Abbate, Vincenzo, Fossataro, Federica, Attanasi, Federica, and Bonavolontà, Giulio

Subjects
medicine.medical_specialty, Lacrimal Apparatus Diseases, integumentary system, Orbital exenteration, business.industry, Eye Neoplasms, Carcinoma, Lacrimal Apparatus, Lacrimal gland, Surgery, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Otorhinolaryngology, 030220 oncology & carcinogenesis, 030221 ophthalmology & optometry, Overall survival, medicine, Humans, Orbital Neoplasms, Statistical analysis, In patient, business, Lacrimal Gland Carcinoma, Retrospective Studies
Abstract

BACKGROUND This study examined whether eye-sparing surgery is associated with better or worse outcomes than exenteration for the treatment of lacrimal gland carcinomas. METHODS Forty-six patients treated for lacrimal gland carcinoma were retrospectively reviewed and compared. A statistical analysis was performed using Kaplan-Meier plots. RESULTS The overall survival rates for eye-sparing surgery were 52% and 37% at 5 and 10 years, and those for exenteration were 37% and 25% at 5 and 10 years, respectively (P = .73). The proportion of patients with local regional control at both 5 and 10 years after eye-sparing surgery was 0.75, and that for exenteration was 0.47 (P = .30). For eye-sparing surgery, the proportions of distant metastasis-free survival at 5 and 10 years were 0.51 and 0.39 for eye-sparing surgery and 0.29 and 0.14 for exenteration (P = .50). CONCLUSION Because the outcomes were not significantly different, the authors suggest that eye-sparing surgery can be proposed as a reasonable approach for lacrimal gland carcinomas in appropriately selected patients.

Published
2020

11. The epidemiological analysis of maxillofacial fractures in Italy: The experience of a single tertiary center with 1720 patients

Author

Marzia Petrocelli, Luigi Angelo Vaira, Giacomo De Riu, Giorgio Iaconetta, Carmelo Lo Faro, Giovanni Dell'Aversana Orabona, Paola Bonavolontà, Federica Attanasi, Vincenzo Abbate, Luigi Califano, Bonavolonta', Paola, DELL'AVERSANA ORABONA, Giovanni, Abbate, Vincenzo, Vaira, LUIGI ANGELO, Lo Faro, Carmelo, Petrocelli, Marzia, Attanasi, Federica, De Riu, Giacomo, Iaconetta, Giorgio, and Califano, Luigi

Subjects
Adult, Male, Maxillofacial fracture, medicine.medical_specialty, Time Factors, Dentistry, Poison control, Suicide prevention, Facial Bones, Maxillary Fractures, Occupational safety and health, Maxillofacial fractures, Maxillofacial fractures epidemiology, Tertiary Care Centers, 03 medical and health sciences, 0302 clinical medicine, Injury prevention, Epidemiology, Maxillofacial fractures, Maxillofacial injuries, Maxillofacial fractures epidemiology, medicine, Humans, 030223 otorhinolaryngology, Retrospective Studies, Skull Fractures, business.industry, Public health, General surgery, Otorhinolaryngology2734 Pathology and Forensic Medicine, Human factors and ergonomics, 030206 dentistry, Middle Aged, Maxillofacial injuries, Surgery, Oral Surgery, Epidemiologic Studies, Italy, Otorhinolaryngology, Etiology, Female, business
Abstract

Purpose Maxillofacial fractures represent a serious public health problem. Their epidemiology is extremely variable, and its analysis is crucial to establish effective treatment and prevention of these injuries. However only two works have been published about maxillofacial fracture epidemiology in Italy. Materials and methods The records of 1720 patients diagnosed with maxillofacial fractures in a 15-years period (2001–2015) in our department were retrospectively reviewed. Results A total of 1108 male and 612 female patients were included in the study. The most frequent aetiology of fracture was road traffic injuries (57.1%), followed by assault (21.7%), falls (14.2%), work accidents (3.5%), sport accidents (3.3%) and other causes (0.2%). Significant variations of aetiology were detected between males and females and between Italians and individuals from other countries. The most frequently observed fracture involved the mandible (861 cases, 36%), followed by zygoma (489 cases, 20.4%), orbital walls (386 cases, 16.1%) and maxilla (282 cases, 11.8%). Conclusion Road traffic legislation enforcement and continuous public education regarding the use of security devices remain an ongoing problem in our region and should be encouraged. In the same way, as migration flows influence and change the epidemiology of facial traumas, it is crucial to establish social support programs that avoid these disadvantaged categories of victims of violence and crime.

Published
2017

12. Complications after orthognathic surgery: our experience on 423 cases

Author

Carolina Sbordone, Luigi Angelo Vaira, Mariano Paternoster, Giorgio Iaconetta, Francesco Maria Cassandro, Federica Attanasi, Marco Friscia, Marzia Petrocelli, Luigi Califano, Friscia, Marco, Sbordone, Carolina, Petrocelli, Marzia, Vaira, LUIGI ANGELO, Attanasi, Federica, Cassandro, Francesco Maria, Paternoster, Mariano, Iaconetta, Giorgio, and Califano, Luigi

Subjects
Adult, Male, medicine.medical_specialty, Mandibular Nerve, medicine.medical_treatment, Orthognathic surgery, Lingual Nerve, Postoperative Hemorrhage, Osteotomy, 03 medical and health sciences, Postoperative Complications, 0302 clinical medicine, Risk Factors, medicine, Inferior alveolar nerve injurie, Humans, Surgical Wound Infection, Maxillofacial surgery department, Statistical analysis, Sagittal split ramus osteotomy complications, Intraoperative Complications, Retrospective Studies, Fixation (histology), business.industry, Medical record, Orthognathic Surgery, 030206 dentistry, Le Fort 1 osteotomy complication, Surgery, Otorhinolaryngology, 030220 oncology & carcinogenesis, Oral and maxillofacial surgery, Joint disorder, Female, Trigeminal Nerve Injuries, Oral Surgery, business, Orthognathic surgery Orthognathic surgery complications Inferior alveolar nerve injuries Sagittal split ramus osteotomy complications Le Fort 1 osteotomy complications, Orthognathic surgery complication, Malocclusion
Abstract

Orthognathic surgery is widely used to correct dentofacial discrepancies. However, this procedure presents numerous possible complications. The aim of our study is to review intraoperative and postoperative complications related to orthognathic surgery based upon a 10-year period in the Maxillofacial Surgery Department of Federico II University of Naples. Medical records of 423 patients who undergone orthognathic surgery in a 10-year period were retrospectively analyzed and complications was noted. Statistical analysis was conduced in order to understand if the type of surgical procedure influenced complications rate. One hundred eighty-five complications in 143 (33.8%) of the 423 treated patients were reported. Complications detected were nerve injury (49 cases, 11.9%), infections (10 cases, 2.4%), complications related to fixation plates or screws (30 cases, 7.1%), bad split osteotomy (8 cases, 1.9%), secondary temporo-mandibular joint disorders (36 cases, 8.5%), dental injuries (21 cases, 5%), condilar resorption (2 cases, 0.5%), and necessity of a second-time surgery (24 cases, 5.7%). Serious complications seem to be quite rare in orthognathic surgery. Some of the surgical complications found are related to the surgeon experience and not strictly to the risks of the operation itself. Understanding potential complications allows the surgeon to guarantee safe care through early intervention and correctly inform the patient in the preoperative colloquy.

Published
2017

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