126 results on '"Anand, Pallavi"'
Search Results
2. You Can’t Climb a Broken Ladder: Examining Underrepresentation of Multiply-Disadvantaged Groups in Secure and Senior Roles in UK Geochemistry
- Author
-
Anand, Pallavi, primary, Bots, Pieter, additional, Gagnon, Jessica, additional, Appiah, Francis, additional, Maters, Elena, additional, Bhagwat, Shonil, additional, Little, Susan, additional, Riches, Amy, additional, ChiFru, Ernest, additional, Lawrence, Anya, additional, and Ngwenya, Bryne, additional
- Published
- 2024
- Full Text
- View/download PDF
3. Synergistic impacts of anthropogenic fires and aridity on plant diversity in the Western Ghats: Implications for management of ancient social-ecological systems
- Author
-
Kulkarni, Charuta, Finsinger, Walter, Anand, Pallavi, Nogué, Sandra, and Bhagwat, Shonil A.
- Published
- 2021
- Full Text
- View/download PDF
4. Comparison of micromorphological changes in enamel using SEM analysis after conventional and erbium, chromium:yttrium, scandium, gallium, and garnet hard-tissue laser fissurotomy: An in vitro study
- Author
-
Aggarwal, Priyanka, Anand, Pallavi, Singh, Kopal, Jhingan, Pulkit, Malik, Manvi, and Mathur, Shivani
- Subjects
Rare earth metals ,Dental caries ,Lasers ,Laser ,Health - Abstract
Byline: Priyanka. Aggarwal, Pallavi. Anand, Kopal. Singh, Pulkit. Jhingan, Manvi. Malik, Shivani. Mathur Background: Well articulated by John Knowles - 'Everything has to evolve or else it perishes.' With the [...]
- Published
- 2023
5. Climate tipping point interactions and cascades : a review
- Author
-
Wunderling, Nico, von der Heydt, Anna S., Aksenov, Yevgeny, Barker, Stephen, Bastiaansen, Robbin, Brovkin, Victor, Brunetti, Maura, Couplet, Victor, Kleinen, Thomas, Lear, Caroline H., Lohmann, Johannes, Roman-Cuesta, Rosa Maria, Sinet, Sacha, Swingedouw, Didier, Winkelmann, Ricarda, Anand, Pallavi, Barichivich, Jonathan, Bathiany, Sebastian, Baudena, Mara, Bruun, John T., Chiessi, Cristiano M., Coxall, Helen K., Docquier, David, Donges, Jonathan, Falkena, Swinda K. J., Klose, Ann Kristin, Obura, David, Rocha, Juan, Rynders, Stefanie, Steinert, Norman Julius, Willeit, Matteo, Wunderling, Nico, von der Heydt, Anna S., Aksenov, Yevgeny, Barker, Stephen, Bastiaansen, Robbin, Brovkin, Victor, Brunetti, Maura, Couplet, Victor, Kleinen, Thomas, Lear, Caroline H., Lohmann, Johannes, Roman-Cuesta, Rosa Maria, Sinet, Sacha, Swingedouw, Didier, Winkelmann, Ricarda, Anand, Pallavi, Barichivich, Jonathan, Bathiany, Sebastian, Baudena, Mara, Bruun, John T., Chiessi, Cristiano M., Coxall, Helen K., Docquier, David, Donges, Jonathan, Falkena, Swinda K. J., Klose, Ann Kristin, Obura, David, Rocha, Juan, Rynders, Stefanie, Steinert, Norman Julius, and Willeit, Matteo
- Abstract
Climate tipping elements are large-scale subsystems of the Earth that may transgress critical thresholds (tipping points) under ongoing global warming, with substantial impacts on the biosphere and human societies. Frequently studied examples of such tipping elements include the Greenland Ice Sheet, the Atlantic Meridional Overturning Circulation (AMOC), permafrost, monsoon systems, and the Amazon rainforest. While recent scientific efforts have improved our knowledge about individual tipping elements, the interactions between them are less well understood. Also, the potential of individual tipping events to induce additional tipping elsewhere or stabilize other tipping elements is largely unknown. Here, we map out the current state of the literature on the interactions between climate tipping elements and review the influences between them. To do so, we gathered evidence from model simulations, observations, and conceptual understanding, as well as examples of paleoclimate reconstructions where multi-component or spatially propagating transitions were potentially at play. While uncertainties are large, we find indications that many of the interactions between tipping elements are destabilizing. Therefore, we conclude that tipping elements should not only be studied in isolation, but also more emphasis has to be put on potential interactions. This means that tipping cascades cannot be ruled out on centennial to millennial timescales at global warming levels between 1.5 and 2.0 ∘C or on shorter timescales if global warming surpassed 2.0 ∘C. At these higher levels of global warming, tipping cascades may then include fast tipping elements such as the AMOC or the Amazon rainforest. To address crucial knowledge gaps in tipping element interactions, we propose four strategies combining observation-based approaches, Earth system modeling expertise, computational advances, and expert knowledge.
- Published
- 2024
- Full Text
- View/download PDF
6. Climate tipping point interactions and cascades: a review
- Author
-
Marine and Atmospheric Research, Sub Physical Oceanography, Sub Mathematical Modeling, Sub Algemeen Marine & Atmospheric Res, Spatial Ecology and Global Change, Wunderling, Nico, Heydt, Anna S von der, Aksenov, Yevgeny, Barker, Stephen, Bastiaansen, Robbin, Brovkin, Victor, Brunetti, Maura, Couplet, Victor, Kleinen, Thomas, Lear, Caroline, Lohmann, Johannes Jakob, Roman-Cuesta, Rosa Maria, Sinet, Sacha, Swingedouw, Didier, Winkelmann, Ricarda, Anand, Pallavi, Barichivich, Jonathan, Bathiany, Sebastian, Baudena, Mara, Bruun, John, Chiessi, Cristiano, Coxall, Helen, Docquier, David, Donges, Jonathan, Falkena, Swinda K.J., Klose, Ann Kristin, Obura, David, Rocha, Juan Carlos, Rynders, Stefanie, Steinert, Norman J., Willeit, Matteo, Marine and Atmospheric Research, Sub Physical Oceanography, Sub Mathematical Modeling, Sub Algemeen Marine & Atmospheric Res, Spatial Ecology and Global Change, Wunderling, Nico, Heydt, Anna S von der, Aksenov, Yevgeny, Barker, Stephen, Bastiaansen, Robbin, Brovkin, Victor, Brunetti, Maura, Couplet, Victor, Kleinen, Thomas, Lear, Caroline, Lohmann, Johannes Jakob, Roman-Cuesta, Rosa Maria, Sinet, Sacha, Swingedouw, Didier, Winkelmann, Ricarda, Anand, Pallavi, Barichivich, Jonathan, Bathiany, Sebastian, Baudena, Mara, Bruun, John, Chiessi, Cristiano, Coxall, Helen, Docquier, David, Donges, Jonathan, Falkena, Swinda K.J., Klose, Ann Kristin, Obura, David, Rocha, Juan Carlos, Rynders, Stefanie, Steinert, Norman J., and Willeit, Matteo
- Published
- 2024
7. Climate tipping point interactions and cascades:a review
- Author
-
Wunderling, Nico, Von Der Heydt, Anna S., Aksenov, Yevgeny, Barker, Stephen, Bastiaansen, Robbin, Brovkin, Victor, Brunetti, Maura, Couplet, Victor, Kleinen, Thomas, Lear, Caroline H., Lohmann, Johannes, Roman-cuesta, Rosa Maria, Sinet, Sacha, Swingedouw, Didier, Winkelmann, Ricarda, Anand, Pallavi, Barichivich, Jonathan, Bathiany, Sebastian, Baudena, Mara, Bruun, John T., Chiessi, Cristiano M., Coxall, Helen K., Docquier, David, Donges, Jonathan F., Falkena, Swinda K. J., Klose, Ann Kristin, Obura, David, Rocha, Juan, Rynders, Stefanie, Steinert, Norman Julius, Willeit, Matteo, Wunderling, Nico, Von Der Heydt, Anna S., Aksenov, Yevgeny, Barker, Stephen, Bastiaansen, Robbin, Brovkin, Victor, Brunetti, Maura, Couplet, Victor, Kleinen, Thomas, Lear, Caroline H., Lohmann, Johannes, Roman-cuesta, Rosa Maria, Sinet, Sacha, Swingedouw, Didier, Winkelmann, Ricarda, Anand, Pallavi, Barichivich, Jonathan, Bathiany, Sebastian, Baudena, Mara, Bruun, John T., Chiessi, Cristiano M., Coxall, Helen K., Docquier, David, Donges, Jonathan F., Falkena, Swinda K. J., Klose, Ann Kristin, Obura, David, Rocha, Juan, Rynders, Stefanie, Steinert, Norman Julius, and Willeit, Matteo
- Published
- 2024
8. Tectonic and climatic drivers of Asian monsoon evolution
- Author
-
Thomson, James R., Holden, Philip B., Anand, Pallavi, Edwards, Neil R., Porchier, Cécile A., and Harris, Nigel B. W.
- Published
- 2021
- Full Text
- View/download PDF
9. Dipole patterns in tropical precipitation were pervasive across landmasses throughout Marine Isotope Stage 5
- Author
-
Nilsson-Kerr, Katrina, Anand, Pallavi, Holden, Philip B., Clemens, Steven C., and Leng, Melanie J.
- Published
- 2021
- Full Text
- View/download PDF
10. Compound Odontoma in Anterior Maxilla in a 10-year-old Pediatric Patient: A Case Report with 44 Denticles Extracted
- Author
-
Aggarwal, Priyanka, primary, Jhingan, Pulkit, additional, Mathur, Shivani, additional, Singh, Kopal, additional, Anand, Pallavi, additional, and Malik, Manvi, additional
- Published
- 2023
- Full Text
- View/download PDF
11. Global Tipping Points Report 2023: Ch1.5: Climate tipping point interactions and cascades.
- Author
-
Wunderling, Nico, von der Heydt, Anna, Aksenov, Yevgeny, Barker, Stephen, Bastiaansen, Robbin, Brovkin, Victor, Brunetti, Maura, Couplet, Victor, Kleinen, Thomas, Lear, Caroline H., Lohmann, Johannes, Roman-Cuesta, Rosa M., Sinet, Sacha, Swingedouw, Didier, Winkelmann, Ricarda, Anand, Pallavi, Barichivich, Jonathan, Bathiany, Sebastian, Baudena, Mara, Bruun, John T., Chiessi, Cristiano M., Coxall, Helen K., Docquier, David, Donges, Jonathan F., Falkena, Swinda K.J., Klose, Ann Kristin, Obura, David, Rocha, Juan, Rynders, Stefanie, Steinert, Norman J., Willeit, Matteo, Wunderling, Nico, von der Heydt, Anna, Aksenov, Yevgeny, Barker, Stephen, Bastiaansen, Robbin, Brovkin, Victor, Brunetti, Maura, Couplet, Victor, Kleinen, Thomas, Lear, Caroline H., Lohmann, Johannes, Roman-Cuesta, Rosa M., Sinet, Sacha, Swingedouw, Didier, Winkelmann, Ricarda, Anand, Pallavi, Barichivich, Jonathan, Bathiany, Sebastian, Baudena, Mara, Bruun, John T., Chiessi, Cristiano M., Coxall, Helen K., Docquier, David, Donges, Jonathan F., Falkena, Swinda K.J., Klose, Ann Kristin, Obura, David, Rocha, Juan, Rynders, Stefanie, Steinert, Norman J., and Willeit, Matteo
- Abstract
This chapter reviews interactions between climate tipping systems and assesses the potential risk of cascading effects. After a definition of tipping system interactions, we map out the current state of the literature on specific interactions between climate tipping systems that may be important for the overall stability of the climate system. For this, we gather evidence from model simulations, observations and conceptual understanding, as well as archetypal examples of palaeoclimate reconstructions where propagating transitions were potentially at play. This chapter concludes by identifying crucial knowledge gaps in tipping system interactions that should be resolved in order to improve risk assessments of cascading transitions under future climate change scenarios.
- Published
- 2023
12. Extent and impact of microplastics on soil nutrients and biota: a trade-off assessment
- Author
-
Jesionkowska, Joanna, Araya, Yoseph, and Anand, Pallavi
- Subjects
microplastics ,sewage sludge ,terrestrial ,soil nutrients ,soil - Abstract
While water treatment plants effectively remove microplastics from influent water, microplastics get concentrated in the sludge. This sewage is subsequently spread in agricultural soils for crop production. Sewage sludge can supply a large part of the nitrogen or phosphorus that most crops need. It's also a good source of organic matter that can improve the water-retaining capacity and structure of soil. However, sludge contains potentially toxic elements, such as heavy metals, pathogens, antibiotics, as well as microplastics. Once in soil, microplastics could induce changes in soil fertility and also pose a potential threat to plant performance and crop productivity. The objective of this study is to review the extent of microplastics added from the sludge, the potential impacts of sludge amendment on nutrient availability and soil biota, in order to reveal the trade-off between benefits and risks of using sewage sludge from the perspective of microplastic pollutants. Also see: https://micro2022.sciencesconf.org/426896/document, In MICRO 2022, Online Atlas Edition: Plastic Pollution from MACRO to nano
- Published
- 2022
- Full Text
- View/download PDF
13. Gender balance and geographical diversity in editorial boards of Geochimica et Cosmochimica Acta and Chemical Geology
- Author
-
Pourret, Olivier, primary, Anand, Pallavi, additional, Bots, Pieter, additional, Cottrell, Elizabeth, additional, Dosseto, Anthony, additional, Gunter, Ashley, additional, Hedding, David W., additional, Ibarra, Daniel Enrique, additional, Irawan, Dasapta Erwin, additional, Johannesson, Karen, additional, Labidi, Jabrane, additional, Little, Susan, additional, Liu, Haiyan, additional, Makhubela, Tebogo Vincent, additional, Marin Carbonne, Johanna, additional, Perez-Fodich, Alida, additional, Riches, Amy, additional, Tartèse, Romain, additional, and Tripati, Aradhna, additional
- Published
- 2022
- Full Text
- View/download PDF
14. Climate tipping point interactions and cascades: A review.
- Author
-
Wunderling, Nico, von der Heydt, Anna, Aksenov, Yevgeny, Barker, Stephen, Bastiaansen, Robbin, Brovkin, Victor, Brunetti, Maura, Couplet, Victor, Kleinen, Thomas, Lear, Caroline H., Lohmann, Johannes, Roman-Cuesta, Rosa Maria, Sinet, Sacha, Swingedouw, Didier, Winkelmann, Ricarda, Anand, Pallavi, Barichivich, Jonathan, Bathiany, Sebastian, Baudena, Mara, and Bruun, John T.
- Subjects
ATLANTIC meridional overturning circulation ,GREENLAND ice ,ICE sheets - Abstract
Climate tipping elements are large-scale subsystems of the Earth that may transgress critical thresholds (tipping points) under ongoing global warming, with substantial impacts on biosphere and human societies. Frequently studied exam- ples of such tipping elements include the Greenland Ice Sheet, the Atlantic Meridional Overturning Circulation, permafrost, monsoon systems, and the Amazon rainforest. While recent scientific efforts have improved our knowledge about individual tipping elements, the interactions between them are less well understood. Also, the potential of individual tipping events to induce additional tipping elsewhere, or stabilize other tipping elements is largely unknown. Here, we map out the current state of the literature on the interactions between climate tipping elements and review the influences between them. To do so, we gathered evidence from model simulations, observations and conceptual understanding, as well as archetypal examples of paleoclimate reconstructions where multi-component or spatially propagating transitions were potentially at play. Lastly, we identify crucial knowledge gaps in tipping element interactions and outline how future research could address those gaps. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
15. Inter-comparison of antimicrobial photodynamic therapy, LASER, and an antifungal agent as adjunct intracanal irrigation techniques to standard disinfection protocols in reducing Candida albicans counts in the root canals of primary teeth: A pilot study
- Author
-
Anand, Pallavi, Mathur, Shivani, Sachdev, Vinod, and Jain, Anshi
- Subjects
Root canal therapy -- Methods -- Comparative analysis ,Antifungal agents -- Standards ,Photochemotherapy -- Comparative analysis -- Methods ,Infection -- Methods -- Comparative analysis ,Methylene blue -- Standards ,EDTA -- Standards ,Infection control -- Comparative analysis -- Methods ,Health - Abstract
Byline: Pallavi. Anand, Shivani. Mathur, Vinod. Sachdev, Anshi. Jain Background: Despite endodontic infections being a common problem in the primary dentition, some of the infected primary teeth can remain functional [...]
- Published
- 2020
16. Indian Summer Monsoon variability 140–70 thousand years ago based on multi-proxy records from the Bay of Bengal
- Author
-
Nilsson-Kerr, Katrina, Anand, Pallavi, Sexton, Philip F., Leng, Melanie J., Naidu, Pothuri Diwakar, Nilsson-Kerr, Katrina, Anand, Pallavi, Sexton, Philip F., Leng, Melanie J., and Naidu, Pothuri Diwakar
- Abstract
Understanding the Indian Summer Monsoon (ISM) behaviour during the late Pleistocene has been largely based on the wind-driven upwelling records from the Arabian Sea. However, it remains unclear the extent to which these records can also be used to infer a concomitant signal of monsoon rainfall, or how the two ISM components, rainfall and wind, are linked on millennial timescales. In order to isolate a primary signal of ISM rainfall, we exploit two deep sea sediment cores from the northern Bay of Bengal (Site U1446) and Andaman Sea (Site U1448), both situated proximal to the South Asian continent, and thus ideally situated for capturing ISM rainfall and fluvial runoff. By comparing our multi-proxy ISM rainfall and runoff records with published ISM wind-driven records from the Arabian Sea, we observe pronounced decoupling of the rainfall and wind components of the ISM across Marine Isotope Stage 5/6 (∼140–70 thousand years ago). We reveal that the relative dominance of barometric dynamics (wind) and the thermodynamic (rainfall) components of the monsoon shifts with changes in background climate state. This finding constitutes an important consideration for the interpretation of past monsoon reconstructions. By comparing our new ISM rainfall records with high latitude climate records, we show that moisture export from low-latitudes, via the monsoon, could have preconditioned the high latitudes for ice sheet growth during glacial inceptions.
- Published
- 2022
17. Assessing diversity and inclusion within the UK’s geochemistry academic workforce
- Author
-
Anand, Pallavi, Appiah, Francis, Lawrence, Anya, Bots, Pieter, Gagnon, Jessica, Bhagwat, Shonil, Riches, Amy J. V, Little, Susan, Maters, Elena, Chi Fru, Ernest, and Ngwenya, Bryne
- Abstract
Geochemistry is applied across Earth, environmental and planetary geoscience research. Yet, the first specific workforce diversity data for geochemistry is only now being collected (e.g. EAG-GS led 2022 Global Geochemistry Community Survey). Additionally, national effort is underway to scrutinise detailed and intersectional diversity data (e.g., race, ethnicity, gender identity, sexual orientation, disability, socioeconomic background, career path) for UK geochemists via ‘Evaluating Diversity and Inclusion within the (geochemistry) Academic Ladder (E-DIAL)’, a project funded by the UK’s Natural Environmental Research Council. This project will also collect data to evidence workplace structures and policies specific to the UK’s geochemists. We will present key findings linked to the geochemistry workforce, including laboratory support staff, from among our survey results to provide a snapshot of the demographics and intersectional representation among the UK geochemistry community within Higher Education Institutes (HEIs). An important facet of this work is our focus on how the allocation, accessibility, and support of geochemistry laboratories are distributed and experienced by all members of the UK community. Furthermore, the study will report on salient aspects of COVID-19 generated impacts and inequities within the geochemistry community. We also present specific findings for experiences that capture evidence of some persisting barriers to individuals and/or geochemistry groups. These exclusionary hurdles include cultural and other obstacles for which we suggest remedies that will advance the representation and further the success of people of minoritised identities within and across the academic ladder. We aim to use our project findings to develop recommendations for policy and structural reforms\ud among UK HEIs. These actions will ensure sustained progress for accessibility in geochemistry, improved career experiences and representation among geochemists, and shall help people of all identities to realise equitable career progression in the short and long-term. These policy developments and reforms are critical to improving diversity and inclusion not only within UK geosciences, but in wider STEM.
- Published
- 2022
18. Are diverse geochemists retained and thriving on the UK academic ladder?
- Author
-
Maters, Elena, Appiah, Francis, Lawrence, Anya, Bots, Pieter, Gagnon, Jessica, Riches, Amy, Bhagwat, Shonil, Chi Fru, Ernest, Little, Susan, Ngwenya, Bryne, and Anand, Pallavi
- Abstract
Evaluating Diversity and Inclusion within the (geochemistry) Academic Ladder (E-DIAL), funded by the UK’s Natural Environment Research Council, provides a snapshot of diversity and identifies barriers resulting in underrepresentation among intersectional identity groups across the UK geochemistry community. The project emphasis is on the academic ladder within UK higher education institutions (HEIs). As a multi-faceted discipline, geochemistry is central to Earth, environmental and planetary sciences, yet the first specific geochemistry workforce data is only now being collected (e.g., through the 2022 Global Geochemistry Community Survey launched by the European Association of Geochemistry and Geochemical Society). In complement to this timely society-led effort serving the international geochemistry community, our project collects original data and evidence through a UK-wide survey that captures coupled diversity and academic progression and retention data. These data are vital to catalyse policies that actively improve geochemistry career prospects for diverse talents, given that a community’s scientific potential can only be reached by including everyone. Specifically, the UK-wide survey data examines information on past and recent rates of appointment, progression and retention of both majority and under-represented groups across all levels of seniority, including research students, within UK HEIs.In profiling geochemists’ career pathways and evidencing lived experiences (e.g., among postdocs), exclusionary obstacles are identified with resultant understanding driving revision of prevailing policies, attitudes and practices while assessing implementation effectiveness at HEIs with, for example, differing diversity certifications (e.g., Athena Swan or Race Equality Charters). Findings will test the hypothesis that “there is an erosion of diversity within geochemistry careers.” To accelerate widespread change, E-DIAL will engage in diplomacy and action at institutional, funding agency and parliamentary levels. Our approach optimises study effectiveness by ensuring that project findings and recommendations for reform within UK HEIs reach communities and decision makers at all levels, with the intention of influencing UK system change to improve diversity and inclusion while establishing practice for continued monitoring. As a national-level project linked to society efforts on the global stage, E-DIAL provides a starting model for similar studies to be carried out among other nations. We therefore urge wider funding agencies to engage in and sustain financial support of such collaborative cross-disciplinary research because this work and its impact on STEM governance is critical to advancing justice, diversity, inclusion, equity and excellence in and beyond academia.
- Published
- 2022
19. A study on adiponectin, uric acid, and C-reactive protein in prediabetic and diabetic subjects
- Author
-
Sharma, Rachna, primary, Anand, Pallavi, additional, and Kumar, Shrawan, additional
- Published
- 2022
- Full Text
- View/download PDF
20. Diversity, Equity, and Inclusion: tackling under-representation and recognition of talents
- Author
-
Pourret, Olivier, Anand, Pallavi, Arndt, Sandra, Bots, Pieter, Dosseto, Anthony, Li, Zimin, Carbonne, Johanna Marin, Middleton, Jennifer, Ngwenya, Bryne, and Riches, Amy
- Abstract
Diversity, at every step along the scientific path, drives innovative research. Scientific societies, like the Geochemical Society (GS) and the European Association of Geochemistry (EAG), have a significant influence over which discoveries and innovators are celebrated. Such choices impact the future of research, and therefore influence the evolution of our discipline and its relationship to the global community. Our professional societies are well positioned to define and promote the success of all scientists, including those from under-represented groups, through proactive advocacy, inclusive mentorship, awards, and leadership. At present, only binary gender data are available to examine the distribution of under-represented groups among memberships, awardees, and leadership positions. To assess gender diversity in the geochemistry and cosmochemistry community, we have reviewed available records of GS and EAG membership through Goldschmidt Conference attendees, and compared these to awardees and leadership data.Awards have in the past been disproportionately given to white men, though this is changing. The GS and EAG have taken positive steps to increase both diversity of awardees (e.g., broadened definition of Fellows criteria) and inclusion (e.g., mentoring efforts aimed at early career and underrepresented minority scientists). This work identifies strategies to continue to improve professional societies’ recognition of excellent science resulting in a more diverse representation of awardees. The strategies (e.g., revisions to award criteria and procedures to enlarge and diversify nomination pools) will require ongoing analysis and modifications. Future work is needed to address historically under-represented groups. We must work together to create a legacy of inclusion.
- Published
- 2021
- Full Text
- View/download PDF
21. AUTOBIOGRAPHICAL SKETCHES OF WOMEN IN OCEANOGRAPHY
- Author
-
Delaney, Peggy, Abrantes, Fatima, Alexander, Vera, Alldredge, Alice L., Almogi-Labin, Ahuva, Alonso, Belén, Anand, Pallavi, Ates, Sibel Bargu, Bauch, Dorothea, Bell, Robin E., Benitez-Nelson, Claudia, Benoit-Bird, Kelly, Bergamaschi, Dorothy Eden, Bernhard, Joan M., Billups, Katharina, Bronk, Deborah A., Campbell, Lisa, Canuel, Elizabeth A., Carbotte, Suzanne, Cessi, Paola, Chang, Grace C., Chase, Zanna, Chereskin, Teresa, Chiba, Sanae, Chisholm, Penny, Christeson, Gail, Cita, Maria Bianca, Class, Cornelia, Coble, Paula, Conte, Maureen, Cooke, Penelope, Cormier, Marie-Helene, Crane, Kathleen, Daly, Kendra L., Darling, Kate, de Angelis, Marie, De La Rocha, Christina, Demopoulos, Amanda W.J., Dierssen, Heidi, Druffel, Ellen R.M., Edmonds, Henrietta N., Edwards, Margo, Erba, Elisabetta, Ercilla, Gemma, Escutia, Carlota, Estrada, Marta, Falkner, Kelly Kenison, Fine, Rana A., Frank, Tracy D., Gardner, Joan M., Gargett, Ann, Garzoli, Silvia L., Gibson, Deidre M., Gillis, Kathryn, Gilbert, Patricia M., Goffredi, Shana K., Greengrove, Cheryl, Hall, Julie, Muller, Pamela Hallock, Hamme, Roberta C., Harada, Naomi, Harwood, Lois, Haymon, Rachel M., Heywood, Karen J., Hickey, Barbara M., Hill, Tessa M., Hooft, Emilie, Hummon, Julia M., Humphris, Susan E., Hutchinson, Deborah R., Ingalls, Anitra E., Isern, Alexandra R., Johns, Elizabeth, Joseph, Leah H., Joye, Samantha (Mandy), Kappel, Ellen S., Karp-Boss, Lee, Karsten, Jill, Kastner, Miriam, Kelley, Deborah S., Kim, Stacy, Klein, Emily M., Kominz, Michelle, Lange, Carina B., Lavín, Alicia M., Lavoie, Dawn, Leinen, Margaret S., Levin, Lisa A., Liepert, Beate, Lightsom, Frances, Lozier, M. Susan, Lynch-Stieglitz, Jean, Manley, Patricia Lee, Marcus, Nancy, Martin, Ellen E., Martini, Marinna, Matrai, Patricia A., McAndrew, Patricia, McClean, Julie, McGregor, Bonnie A., McHugh, Cecilia, McLaughlin, Fiona, McNutt, Marcia, McPhee-Shaw, Erika E., Mills, Rachel A., Moran, Kathryn, Mulholland, Margaret R., Muller-Parker, Gisèle, Mullineaux, Lauren, Neil, Helen, Noble, Marlene, O'Connell, Suzanne, Oppo, Delia, Orellana, Mónica V., Özkan-Haller, Tuba, Pascual, Mercedes, Passow, Uta, Paytan, Adina, Pilskaln, Cindy, Pyrtle, Ashanti J., Raffi, Isabella, Ravelo, Christina, Raymo, Maureen, Reguera, Beatriz, Reimers, Clare E., Reysenbach, Anna-Louise, Richardson, Mary Jo, Rickaby, Rosalind E.M., Rii, Shimi, Malanotte-Rizzoli, Paola, Robertson, Robin, Robinson, Rebecca, Rosenfeld, Leslie, Ross, Robin M., Ruppel, Carolyn, Russell, Ann D., Sabatés, Ana, Schwager, Katherine B., Scranton, Mary, Sherr, Evelyn B., Silver, Mary, Sloyan, Bernadette M., Smith, Deborah K., Sosik, Heidi M., Spitz, Yvette H., Stakes, Debra S., Stathoplos, Linda, Steinberg, Deborah K., Szmant, Alina M., Tachikawa, Kazuyo, Talaue-McManus, Liana, Talley, Lynne D., Tauxe, Lisa, Tester, Patricia A., Thomas, Debbie, Thomas, Ellen, Tolstoy, Maya, Torres, Marta E., Tréhu, Anne, Van Dover, Cindy Lee, Vlahos, Penny, Von Damm, Karen L., Wade, Bridget, Ward, Bess B., Wheeler, Patricia A., Whelan, Jean, White, Lisa D., Whitman, Jill M., Winckler, Gisela, Wishner, Karen F., Wright, Dawn, Wright, Elizabeth, Yalçin-Özdilek, Şükran, Yen, Jeannette, Yuan, Xiaojun, Zingone, Adriana, and Ziveri, Patrizia
- Published
- 2005
22. Correlation of HbA1c and dyslipidemia in patients of CKD.
- Author
-
Anand, Pallavi, Kumar, Chandan, Hans, Pankaj, and Ahmed, S.
- Subjects
- *
GLYCOSYLATED hemoglobin , *CHRONIC kidney failure , *HYPERGLYCEMIA , *DYSLIPIDEMIA , *HIGH performance liquid chromatography , *PREDIABETIC state , *CARDIOVASCULAR diseases risk factors - Abstract
Background: The frequency of chronic kidney disease (CKD), a serious health issue, is rising globally, especially in those with metabolic diseases such dysglycemia disorders. The glycated hemoglobin concentration (HbA1c) can reveal dysglycemia diseases, such as the prediabetic state, while also serving as a valuable indicator of mean blood glucose levels during the previous three months. Although it is not always present, dyslipidemia (DLP) is a frequent consequence of increasing renal disease. Elevated triglyceride levels, low HDL cholesterol, and small, dense LDL particle size are characteristics of DLP, a renal and cardiovascular risk factor. Aim: The present study was carried out to investigate the association of CKD with HbA1c, dyslipidemia and electrolytes in pts. of renal failure. Methods and materials: It was a hospital based case-control study. The study was done on 109 patients of CKD as cases and 105 patients as controls who did not have CKD. By using an HPLC (High-Performance Liquid Chromatography) system with affinity columns to separate HbA1c molecules from other hemoglobin molecules, glycated hemoglobin (HbA1c) measurement has been carried out. Based on the proportion of HbAlc peak area to all hemoglobin peak areas, the HbAlc content is determined. Enzymatic color test was used for the quantitative determination of HDL-cholesterol in human serum and plasma on OLYMPUS analyzer. Results: Mean HbA1c of cases is 7.32 (SD 2.82) and control is 5.46 (SD 1:78). Difference is significant p value less than 0.0001.58 CKD patients (53.21%) had HbA1c > 5.6 compared to 36 controls (34.29%) which is significant with p value 0.0060, considered very significant, 95% Confidence Interval 1.256 to 3.783 and odds ratio 2.180.47 (43.12%) CKD patients were diabetic compared to 21(20%) controls as per HbA1c level ≥6.5 with p value 0.0004, considered extremely significant, 95% Confidence Interval: 1.647 to 5.583, odds ratio 3.032.In our study, dyslipidemia was present in 43.12% (n=47) among CKD cases and in 26.67% (n=28) among control group. Using Fisher's Extract test, with 95% Confidence Interval (CI): 1.173 to 3.706, Odds Ratio - 2.085, the p value is 0.0147, considered significant. So, dyslipidemia was present in significant number of CKD patients as compared to control groups. Conclusion: In our study high HbA1c were significantly associated with CKD patients compared to non-CKD individuals. Prevalence of dyslipidemia was significantly higher in CKD group compared to control group in the form of increased TG, LDL and low HDL. According to our country's trend, we have got relevant results indicating emergent epidemics of diabetes, hypertension. [ABSTRACT FROM AUTHOR]
- Published
- 2022
23. Association of Superoxide Dismutase Level in Women with Polycystic Ovary Syndrome
- Author
-
Talat, Arshi, primary, Satyanarayana, P., additional, and Anand, Pallavi, additional
- Published
- 2021
- Full Text
- View/download PDF
24. Evidence of a South Asian proto-monsoon during the Oligocene-Miocene transition
- Author
-
Beasley, Charlotte, Kender, Sev, Giosan, Liviu, Bolton, Clara T., Anand, Pallavi, Leng, Melanie J., Nilsson-Kerr, Katrina, Ullmann, Clemens Vinzenz, Hesselbo, Stephen P., Littler, Kate, Beasley, Charlotte, Kender, Sev, Giosan, Liviu, Bolton, Clara T., Anand, Pallavi, Leng, Melanie J., Nilsson-Kerr, Katrina, Ullmann, Clemens Vinzenz, Hesselbo, Stephen P., and Littler, Kate
- Abstract
The geological history of the South Asian monsoon (SAM) before the Pleistocene is not well-constrained, primarily due to a lack of available continuous sediment archives. Previous studies have noted an intensification of SAM precipitation and atmospheric circulation during the middle Miocene (∼14 Ma), but no records are available to test how the monsoon changed prior to this. In order to improve our understanding of monsoonal evolution, geochemical and sedimentological data were generated for the Oligocene-early Miocene (30–20 Ma) from Indian National Gas Hydrate Expedition 01 Site NGHP-01-01A in the eastern Arabian Sea, at 2,674 m water depth. We find the initial glaciation phase (23.7–23.0 Ma) of the Oligocene-Miocene transition (OMT) to be associated with an increase in water column ventilation and water mass mixing, suggesting an increase in winter monsoon type atmospheric circulation, possibly driven by a relative southward shift of the intertropical convergence zone. During the latter part of the OMT, or “deglaciation” phase (23.0–22.7 Ma), a long-term decrease in Mn (suggestive of deoxygenation), increase in Ti/Ca and dissolution of the biogenic carbonate fraction suggest an intensification of a proto-summer SAM system, characterized by the formation of an oxygen minimum zone in the eastern Arabian Sea and a relative increase of terrigenous material delivered by runoff to the site. With no evidence at this site for an active SAM prior to the OMT we suggest that changes in orbital parameters, as well as possibly changing Tethyan/Himalayan tectonics, caused this step change in the proto-monsoon system at this intermediate-depth site.
- Published
- 2021
25. Perspective: Geological Society of London Scientific Statement: What the geological record tells us about our present and future climate
- Author
-
Lear, Caroline H., Anand, Pallavi, Blenkinsop, Tom, Foster, Gavin L., Gagen, Mary, Hoogakker, Babette, Larter, Robert D., Lunt, Daniel J., McCave, I. Nicholas, McClymont, Erin, Pancost, Richard D., Rickaby, Rosalind E.M., Schultz, David M., Summerhayes, Colin, Williams, Charles J.R., Zalasiewicz, Jan, Lear, Caroline H., Anand, Pallavi, Blenkinsop, Tom, Foster, Gavin L., Gagen, Mary, Hoogakker, Babette, Larter, Robert D., Lunt, Daniel J., McCave, I. Nicholas, McClymont, Erin, Pancost, Richard D., Rickaby, Rosalind E.M., Schultz, David M., Summerhayes, Colin, Williams, Charles J.R., and Zalasiewicz, Jan
- Abstract
Executive Statement: Geology is the science of how the Earth functions and has evolved and, as such, it can contribute to our understanding of the climate system and how it responds to the addition of carbon dioxide (CO2) to the atmosphere and oceans. Observations from the geological record show that atmospheric CO2 concentrations are now at their highest levels in at least the past 3 million years. Furthermore, the current speed of human-induced CO2 change and warming is nearly without precedent in the entire geological record, with the only known exception being the instantaneous, meteorite-induced event that caused the extinction of non-bird-like dinosaurs 66 million years ago. In short, whilst atmospheric CO2 concentrations have varied dramatically during the geological past due to natural processes, and have often been higher than today, the current rate of CO2 (and therefore temperature) change is unprecedented in almost the entire geological past. The geological record shows that changes in temperature and greenhouse gas concentrations have direct impacts on sea-level, the hydrological cycle, marine and terrestrial ecosystems, and the acidification and oxygen depletion of the oceans. Important climate phenomena, such as the El Niño–Southern Oscillation (ENSO) and the monsoons, which today affect the socio-economic stability and food and water security of billions of people, have varied markedly with past changes in climate. Climate reconstructions from around the globe show that climate change is not globally uniform, but tends to exhibit a consistent pattern, with changes at the poles larger than elsewhere. This polar amplification is seen in ancient warmer-than-modern time intervals like the Eocene epoch, about 50 million years ago and, more recently, in the Pliocene, about 3 million years ago. The warmest intervals of the Pliocene saw the disappearance of summer sea ice from the Arctic. The loss of ice cover during the Pliocene was one of the many rapid cl
- Published
- 2021
26. Remote and local drivers of Pleistocene South Asian summer monsoon precipitation: a test for future predictions
- Author
-
Clemens, Steven C., Yamamoto, Masanobu, Thirumalai, Kaustubh, Giosan, Liviu, Richey, Julie N., Nilsson-Kerr, Katrina, Rosenthal, Yair, Anand, Pallavi, McGrath, Sarah M., Clemens, Steven C., Yamamoto, Masanobu, Thirumalai, Kaustubh, Giosan, Liviu, Richey, Julie N., Nilsson-Kerr, Katrina, Rosenthal, Yair, Anand, Pallavi, and McGrath, Sarah M.
- Abstract
© The Author(s), 2021. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Clemens, S. C., Yamamoto, M., Thirumalai, K., Giosan, L., Richey, J. N., Nilsson-Kerr, K., Rosenthal, Y., Anand, P., & McGrath, S. M. Remote and local drivers of Pleistocene South Asian summer monsoon precipitation: a test for future predictions. Science Advances, 7(23), (2021): eabg3848, https://doi.org/10.1126/sciadv.abg3848., South Asian precipitation amount and extreme variability are predicted to increase due to thermodynamic effects of increased 21st-century greenhouse gases, accompanied by an increased supply of moisture from the southern hemisphere Indian Ocean. We reconstructed South Asian summer monsoon precipitation and runoff into the Bay of Bengal to assess the extent to which these factors also operated in the Pleistocene, a time of large-scale natural changes in carbon dioxide and ice volume. South Asian precipitation and runoff are strongly coherent with, and lag, atmospheric carbon dioxide changes at Earth’s orbital eccentricity, obliquity, and precession bands and are closely tied to cross-equatorial wind strength at the precession band. We find that the projected monsoon response to ongoing, rapid high-latitude ice melt and rising carbon dioxide levels is fully consistent with dynamics of the past 0.9 million years., S.C.C. and S.M.M. were supported by U.S. NSF OCE1634774. M.Y. was funded by JSPS grants JPMXS05R2900001 and 19H05595 and JAMSTEC Exp. 353 postcruise study. K.N.-K. and P.A. were supported by UK-IODP, Open University, and NERC (NE/L002493/1), K.T. was supported by the Technology and Research Initiative Fund, Arizona Board of Regents.
- Published
- 2021
27. Diversity, equity, and inclusion: Tackling under-representation and recognition of talents in geochemistry and cosmochemistry
- Author
-
UCL - SST/ELI/ELIE - Environmental Sciences, Pourret, Olivier, Anand, Pallavi, Arndt, Sandra, Bots, Pieter, Dosseto, Anthony, Li, Zimin, Marin Carbonne, Johanna, Middleton, Jennifer, Ngwenya, Bryne, Riches, Amy J.V., UCL - SST/ELI/ELIE - Environmental Sciences, Pourret, Olivier, Anand, Pallavi, Arndt, Sandra, Bots, Pieter, Dosseto, Anthony, Li, Zimin, Marin Carbonne, Johanna, Middleton, Jennifer, Ngwenya, Bryne, and Riches, Amy J.V.
- Abstract
Diversity, at every step along the scientific path, drives innovative research. Scientific societies, like the Geochemical Society (GS) and the European Association of Geochemistry (EAG), have a significant influence over which discoveries and innovators are celebrated. Such choices impact the future of research, and therefore influence the evolution of our discipline and its relationship to the global community. Our professional societies are well positioned to define and promote the success of all scientists, including those from under-represented groups, through proactive advocacy, inclusive mentorship, awards, and leadership. At present, only binary gender data are available to examine the distribution of under-represented groups among memberships, awardees, and leadership positions. To assess gender diversity in the geochemistry and cosmochemistry community, we have reviewed available records of GS and EAG membership through Goldschmidt Conference attendees, and compared these to awardees and leadership data. Awards have in the past been disproportionately given to white men, though this is changing. The GS and EAG have taken positive steps to increase both diversity of awardees (e.g., broadened definition of Fellows criteria) and inclusion (e.g., mentoring efforts aimed at early career and underrepresented minority scientists). This work identifies strategies to continue to improve professional societies’ recognition of excellent science resulting in a more diverse representation of awardees. The strategies (e.g., revisions to award criteria and procedures to enlarge and diversify nomination pools) will require ongoing analysis and modifications. Future work is needed to address historically under-represented groups. We must work together to create a legacy of inclusion.
- Published
- 2021
28. Diversity, equity, and inclusion: Tackling under-representation and recognition of talents in geochemistry and cosmochemistry
- Author
-
Pourret, Olivier, Anand, Pallavi, Arndt, Sandra, Bots, Pieter, Dosseto, Anthony, Li, Zimin, Marin Carbonne, Johanna, Middleton, Jennifer, Ngwenya, Bryne, Riches, Amy A.J.V., Pourret, Olivier, Anand, Pallavi, Arndt, Sandra, Bots, Pieter, Dosseto, Anthony, Li, Zimin, Marin Carbonne, Johanna, Middleton, Jennifer, Ngwenya, Bryne, and Riches, Amy A.J.V.
- Abstract
Diversity, at every step along the scientific path, drives innovative research. Scientific societies, like the Geochemical Society (GS) and the European Association of Geochemistry (EAG), have a significant influence over which discoveries and innovators are celebrated. Such choices impact the future of research, and therefore influence the evolution of our discipline and its relationship to the global community. Our professional societies are well positioned to define and promote the success of all scientists, including those from under-represented groups, through proactive advocacy, inclusive mentorship, awards, and leadership. At present, only binary gender data are available to examine the distribution of under-represented groups among memberships, awardees, and leadership positions. To assess gender diversity in the geochemistry and cosmochemistry community, we have reviewed available records of GS and EAG membership through Goldschmidt Conference attendees, and compared these to awardees and leadership data. Awards have in the past been disproportionately given to white men, though this is changing. The GS and EAG have taken positive steps to increase both diversity of awardees (e.g. broadened definition of Fellows criteria) and inclusion (e.g. mentoring efforts aimed at early career and underrepresented minority scientists). This work identifies strategies to continue to improve professional societies’ recognition of excellent science resulting in a more diverse representation of awardees. The strategies (e.g. revisions to award criteria and procedures to enlarge and diversify nomination pools) will require ongoing analysis and modifications. Future work is needed to address historically under-represented groups. We must work together to create a legacy of inclusion., SCOPUS: re.j, info:eu-repo/semantics/published
- Published
- 2021
29. Remote and local drivers of Pleistocene South Asian summer monsoon precipitation: A test for future predictions
- Author
-
Clemens, Steven C., primary, Yamamoto, Masanobu, additional, Thirumalai, Kaustubh, additional, Giosan, Liviu, additional, Richey, Julie N., additional, Nilsson-Kerr, Katrina, additional, Rosenthal, Yair, additional, Anand, Pallavi, additional, and McGrath, Sarah M., additional
- Published
- 2021
- Full Text
- View/download PDF
30. What can we learn from X-ray fluorescence core scanning data? A paleomonsoon case study
- Author
-
Gebregiorgis, Daniel, Giosan, Liviu, Hathorne, Ed C., Anand, Pallavi, Nilsson-Kerr, Katrina, Plass, Anna, Luckge, Andreas, Clemens, Steven C., Frank, Martin, Gebregiorgis, Daniel, Giosan, Liviu, Hathorne, Ed C., Anand, Pallavi, Nilsson-Kerr, Katrina, Plass, Anna, Luckge, Andreas, Clemens, Steven C., and Frank, Martin
- Abstract
Author Posting. © American Geophysical Union, 2020. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Geochemistry, Geophysics, Geosystems 21(2), (2020): e2019GC008414, doi:10.1029/2019GC008414., X‐ray fluorescence (XRF) core scanning of marine and lake sediments has been extensively used to study changes in past environmental and climatic processes over a range of timescales. The interpretation of XRF‐derived element ratios in paleoclimatic and paleoceanographic studies primarily considers differences in the relative abundances of particular elements. Here we present new XRF core scanning data from two long sediment cores in the Andaman Sea in the northern Indian Ocean and show that sea level related processes influence terrigenous inputs based proxies such as Ti/Ca, Fe/Ca, and elemental concentrations of the transition metals (e.g., Mn). Zr/Rb ratios are mainly a function of changes in median grain size of lithogenic particles and often covary with changes in Ca concentrations that reflect changes in biogenic calcium carbonate production. This suggests that a common process (i.e., sea level) influences both records. The interpretation of lighter element data (e.g., Si and Al) based on low XRF counts is complicated as variations in mean grain size and water content result in systematic artifacts and signal intensities not related to the Al or Si content of the sediments. This highlights the need for calibration of XRF core scanning data based on discrete sample analyses and careful examination of sediment properties such as porosity/water content for reliably disentangling environmental signals from other physical properties. In the case of the Andaman Sea, reliable extraction of a monsoon signal requires accounting for the sea level influence on the XRF data., The staff at the Bremen Core Repository is thanked for their help with core handling and Sam Müller at the University of Kiel provided technical assistance with the XRF scanner. We thank two anonymous reviewers for their insightful comments that improved the manuscript significantly. This work was partially funded through DFG Grant HA 5751/3. P. A. and K. N.‐K. acknowledge support from UK‐IODP and Natural and Environment Research Council, UK. The authors express their thanks to all those who contributed to the success of the National Gas Hydrate Program Expedition 01 (NGHP01) and Expedition 353. The data set supporting the conclusions of this article is available in the PANGEA repository (doi: https://doi.pangaea.de/10.1594/PANGAEA.910533)., 2020-07-10
- Published
- 2020
31. STATUS OF OXIDATIVE STRESS AND LIPID PROFILE IN HYPERTENSIVE PATIENTS OF ABO BLOOD GROUP.
- Author
-
Arora, Shalini, Kumar, Shrawan, Kulkarni, Pawan A., and Anand, Pallavi
- Subjects
ABO blood group system ,THIOBARBITURIC acid test ,HYPERTENSION ,OXIDATIVE stress ,BLOOD grouping & crossmatching - Abstract
Aim The aim of the study was to evaluate the status of oxidative stress and lipid profile in hypertensive patients of blood group A, B, AB and O and compare them with normal healthy controls. Material and Methods This was a case control study conducted on 280 subjects which were divided into two groups containing 140 each healthy and hypertensive of age group between 30 to 60 years. These groups were again divided into four groups according to their blood groups containing 35 subjects in each group. Serum was used for the estimation of lipid profile using standard diagnostic kits. Thiobarbituric acid test was used for the estimation of malondialdehyde content in plasma. haemolysate used for the assay of superoxide dismutase and catalase activity. P value less than 0.05 considered as significant. Results We have observed significantly elevated levels of serum triglycerides and malondialdehyd in group A, B, AB and O hypertensive patients. Serum total cholesterol level was elevated significantly in group A, B and AB along with decreased values of serum HDL-C whereas in group O patients there was non-significant increase in the values of total cholesterol. Superoxide dismutase (SOD) and catalase was significantly decreased in group A, B and AB and whereas in group O there was non-significant decrease in the activities of antioxidant enzymes. Conclusion The study concluded that the patients with blood group A, B and AB are more susceptible to oxidative stress and impaired lipid metabolism as compared to blood group O. [ABSTRACT FROM AUTHOR]
- Published
- 2021
32. Nusinersen versus sham control in later-onset spinal muscular atrophy
- Author
-
Vogt, Sibylle, Krueger, Marcus, Pechmann, Astrid, Rippberger, Bianca, Eckenweiler, Matthias, Schara, Ulrike, Koelbel, Heike, Andres, Barbara, Rupprich, Katrin, Gangfuss, Andrea, Jachertz, Philipp, Della Marina, Adela, Sponemann, Nina, Pane, Markia, Palermo, Concetta, Piastra, Marco, Fanelli, Lavinia, de Sanctis, Roberto, Genovese, Orazio, Antonaci, Laura, Pera, Maria Carmela, Lamendola, Priscilla, Messina, Sonia, Vita, Gianluca, Di Bella, Vincenzo, Sframeli, Maria, Rosa, Matteo, Barcellona, Costanza, Distefano, Maria Grazia, Cavallaro, Filippo, Versaci, Antonio, de Luca, Francesco, Vita, Giuseppe, Nacimento Osorio, Andres, Tizzano, Eduardo, Ortez Gonzalez, Carlos Ignacio, Ortigoza Escobar, Juan Dario, Colomer Oferil, Juame, Medina Cantillo, Julita, Febrer Rotger, Anna, Vigo Morancho, Meritxell, Eldblom, Johanneh, Darin, Niklas, Kroksmark, Anna Karin, Lindstedt, Asa, Michael, Eva, Kimber, Eva, Wahlgren, Lisa, Chan, Sophelia Hoi-Shan, Chim, Stella, Chiu, Joseph, Ho, Alvin Chi Chung, Ip, Jing Kun Janice, Lam, Wendy Wai Man, Ng, Maggie Chui-San, Wan, Connie, Wong, Virginia Chun Nei, Yue, Yvonne, Arakawa, Reiko, Yamauchi, Akemi, Nagata, Satoru, Ito, Yasushi, Nakatsukasa, Hidetsugu, Takeshita, Akiko, Hirasawa, Kyoko, Ikai, Tetsuo, Eto, Kaoru, Otamni, Yui, Takeshima, Yasuhiro, Fukuda, Noroki, Tanaka, Yasuhiro, Shimomura, Hideki, Lee, Tomoko, Shibano, Takayuki, Mercuri, E., Tachikawa, Tomohiro, Darras, B. T., Chae, Jong-Hee, Chiriboga, C. A., Lim, Byung Chan, Day, J. W., Shin, Hyung-Ik, Campbell, C., Kim, Soo Yeon, Connolly, A. M., Choi, Sun Ah, Iannaccone, S. T., Son, Woo Sung, Kirschner, J., Jo, Hyemi, Kuntz, N. L., Chun, Seong Min, Saito, K., Kim, Hyuna, Shieh, P. B., Tulinius, M., Mazzone, E. S., Montes, J., Bishop, K. M., Yang, Q., Foster, R., Gheuens, S., Bennett, C. F., Farwell, W., Schneider, E., de Vivo, D. C., Finkel, R. S., Bradley, Walter G., Kaufmann, Petra, Dickson, Patricia I., Reingold, Stephen C., Davis, Charles S., Arredondo, Kristen, Castro, Diana, Cowie, Margaret, Farrow-Gillespie, Alan, Hebert, Andrew, Kauk, Melissa, Miller, Nancy, Nelson, Leslie, Spain, Thomas, Cappell, Joshua, Constantinescu, Andrei, Cruz, Rosangel, Dastgir, Jahannaz, de Vivo, Darryl, Dunaway, Sally, Engelstad, Kristin, Khandji, Alexander G., Kramer, Samantha, Marra, Jonathan, Popolizio, Molly, Salazar, Rachel, Weimer, Louis H., Aziz-Zaman, Sonya, Lamarca, Nicole, Ghosh, Partha, Al-Ghamdi, Fouad, Liew, Wendy, Graham, Robert, Berde, Charles, Sethna, Navil, Koka, Anjali, Wang, Luke, Laine, Regina, Souris, Michelle, Ordonez, Grace, Harrington, Timothy, Szelag, Heather, Pasternak, Amy, Mirek, Elizabeth, Quigley, Janet, Finkel, Richard, Berry, Debbie, Civitello, Matthew, Endsley, Julie Duke, Eden, Candace, Leon, Wendy, O'Reardon, Kathleen, Sigurdardottir, Laufey, Johnson, Craig, Turner, Jenna, Vega, Melisa, Weber-Guzman, Fabiola, Zinn, Matthias, Rocha, Ana Carolina Tesi, Watson, Karolina, d'Souza, Genevieve, Ramamurthi, R. J., Gee, Richard, Kitsuwa-Lowe, Janis, Hagerman, Katharine, Crasta, Sheela, Welsh, Lesly, Paulose, Shirley, Mcfall, Danielle, Perez, Jennifer, Patnaik, Swetapadma, Sanjanwala, Bharati, Sakamuri, Sarada, Proud, Crystal, Purse, Bona Park, Duong, Trinh Tina, Sampson, Jacinda, Tennekoon, Gihan, Brandsema, John, Glanzman, Allan, Flickinger, Jean, Toms, Michele, Adang, Laura, Stanford, Delores, Mayer, Oscar, Zigmont, Joshua, Chadehumbe, Madeline, Kichula, Elizabeth, Finanger, Erika, Russman, Barry, Roberts, Colin, Frank, Andrea, Benjamin, Danielle, Zilke, Kirsten, Golumbek, Paul T., Zaidman, Craig M., Anand, Pallavi, Gadeken, Rebecca, Siener, Catherine, Kuntz, Nancy, Epstein, Leon, Krueger, Jena, Goldman, Stewart, Krosschell, Kristin, Blomgren, Colleen, Choi, Hyoung Won, Kurz, Jonathan, Parsons, Julie, Janas, Joanne, Yang, Michele, Ballard, Alison, Carry, Terri, Shea, Stephanie, Bielsky, Alan, Booker, Kaylee, Camuto, Alicia, Lord-Halvorson, Sierra, Gibbons, Melissa, Zimmerman, Carl, Allen, Victoria, Fuhr, Peter, Johnson, Hannah, Tran, Vi, Vanderveen, Gina, Shieh, Perry, Fowler, Eileen, Parziale, Nicholas, Rao, Lekha, Skura, Christy, Kelley, Carolyn, Shu, Francy, Oskoui, Maryam, Zielinski, David, Poulin, Chantal, Ingelmo, Pablo Mauricio, Desilets, Sarah Turgeon, Dinunzio, Pamela, Rivera, Gonzalo, Srour, Myriam, Arpin, Stephanie, Goobie, Sharan, Gibson, Paul, Scholtes, Cheryl, Mcdonald, Wendy, Zapata, Eugenio, Nguyen, Cam-Tu Emilie, Servais, Laurent, Gargaun, Elena, Le Moing, Anne-Gaelle, Gidaro, Teresa, Vialle, Raphael, Guye, Marie-Laurence, Lilien, Charlotte, Olliver, Gwenn, Gilabert, Stephanie, Borell, Sabine, Wider, Sabine, Stein, Sabine, Universität Duisburg-Essen = University of Duisburg-Essen [Essen], Department of Paediatrics, Università cattolica del Sacro Cuore = Catholic University of the Sacred Heart [Roma] (Unicatt), Vall d'Hebron University Hospital [Barcelona], CIBER de Enfermedades Raras (CIBERER), Handicaps génétiques de l'enfant (Inserm U393), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Seoul National University Hospital, Max-Planck-Institut für Mikrostrukturphysik (MPI-HALLE), Max-Planck-Gesellschaft, The University of Tokyo (UTokyo), Institut de Chimie Organique et Analytique (ICOA), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université d'Orléans (UO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Institute of Plasma Physics, Chinese Academy of Sciences (ASIPP), Institut Necker Enfants-Malades (INEM - UM 111 (UMR 8253 / U1151)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire de mécanique des solides (LMS), École polytechnique (X)-Mines Paris - PSL (École nationale supérieure des mines de Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), CureSMA [Elk Grove Village, IL, USA], Harvard Medical School [Boston] (HMS), Institute for Marine and Antarctic Studies [Hobart] (IMAS), University of Tasmania [Hobart, Australia] (UTAS), The Hospital for sick children [Toronto] (SickKids), University of Toronto, The Open University [Milton Keynes] (OU), Department of Pediatrics, Feinberg School of Medicine, Northwestern University [Evanston]-Northwestern University [Evanston]-Northwestern University, University Hospital Basel [Basel], McGill University Health Center [Montreal] (MUHC), Service de génétique [Tours], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours)-Hôpital Bretonneau, Service of Clinical Trials and Databases, Institut de Myologie, Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Association française contre les myopathies (AFM-Téléthon)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Association française contre les myopathies (AFM-Téléthon)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Association française contre les myopathies (AFM-Téléthon)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), CHU Amiens-Picardie, Groupe de Recherche sur l'Analyse Multimodale de la Fonction Cérébrale - UMR INSERM_S 1105 (GRAMFC), Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), University of Oxford, Schara, Ulrike (Beitragende*r), Koelbel, Heike (Beitragende*r), Rupprich, Katrin (Beitragende*r), Gangfuss, Andrea (Beitragende*r), Della Marina, Adela (Beitragende*r), and Sponemann, Nina (Beitragende*r)
- Subjects
0301 basic medicine ,Male ,[SDV]Life Sciences [q-bio] ,spinal ,Medizin ,Oligonucleotides ,Spinal Muscular Atrophies of Childhood ,Pediatrics ,law.invention ,Age of Onset ,Child ,Child, Preschool ,Double-Blind Method ,Female ,Humans ,Infant ,Injections, Spinal ,Least-Squares Analysis ,Motor Skills ,Oligonucleotides, Antisense ,Medicine (all) ,0302 clinical medicine ,age of onset ,Randomized controlled trial ,law ,Clinical endpoint ,inglese ,injections ,Motor skill ,motor skills ,General Medicine ,SMA ,Settore MED/26 - NEUROLOGIA ,medicine.anatomical_structure ,female ,Anesthesia ,Nusinersen ,Spinal ,antisense ,preschool ,Injections ,03 medical and health sciences ,least-squares analysis ,Settore MED/39 - NEUROPSICHIATRIA INFANTILE ,Settore MED/41 - ANESTESIOLOGIA ,medicine ,Antisense ,Preschool ,business.industry ,Spinal muscular atrophy ,Motor neuron ,medicine.disease ,030104 developmental biology ,Age of onset ,business ,030217 neurology & neurosurgery - Abstract
Background: Nusinersen is an antisense oligonucleotide drug that modulates pre–messenger RNA splicing of the survival motor neuron 2 (SMN2) gene. It has been developed for the treatment of spinal muscular atrophy (SMA). Methods: We conducted a multicenter, double-blind, sham-controlled, phase 3 trial of nusinersen in 126 children with SMA who had symptom onset after 6 months of age. The children were randomly assigned, in a 2:1 ratio, to undergo intrathecal administration of nusinersen at a dose of 12 mg (nusinersen group) or a sham procedure (control group) on days 1, 29, 85, and 274. The primary end point was the least-squares mean change from baseline in the Hammersmith Functional Motor Scale–Expanded (HFMSE) score at 15 months of treatment; HFMSE scores range from 0 to 66, with higher scores indicating better motor function. Secondary end points included the percentage of children with a clinically meaningful increase from baseline in the HFMSE score (≥3 points), an outcome that indicates improvement in at least two motor skills. Results: In the prespecified interim analysis, there was a least-squares mean increase from baseline to month 15 in the HFMSE score in the nusinersen group (by 4.0 points) and a least-squares mean decrease in the control group (by –1.9 points), with a significant between-group difference favoring nusinersen (least-squares mean difference in change, 5.9 points; 95% confidence interval, 3.7 to 8.1; P Conclusions: Among children with later-onset SMA, those who received nusinersen had significant and clinically meaningful improvement in motor function as compared with those in the control group. (Funded by Biogen and Ionis Pharmaceuticals; CHERISH ClinicalTrials.gov number, NCT02292537. opens in new tab.)
- Published
- 2018
- Full Text
- View/download PDF
33. Incidence of Helicobacter Pylori in upper gastrointestinal lesion
- Author
-
Kumar, Vikas, Nag, B. P., Anand, Pallavi, Joshi, Narayani, Jain, Renu, Kumar, Vikas, Nag, B. P., Anand, Pallavi, Joshi, Narayani, and Jain, Renu
- Abstract
Introduction: Helicobacter pylori are gram-negative bacillus. It is noninvasive and live in gastric mucus, with the small proportion of bacteria adherent to the mucosa. Its spiral shape and flagella render Helicobacter pylori motile in mucus environment. Helicobacter pylori is an important pathogen in human causing chronic gastritis and playing a major role in the development of peptic ulcers and gastric cancer. Material and Methods: Study was conducted in Mahatma Gandhi Medical College and hospital, Jaipur (from Jan 2014 to March 2015). 57 Gastrointestinal biopsies were taken who have symptom of dyspepsia. All biopsies taken from different sites were brought in 10%buffered formalin. After overnight fixation in formalin, the tissues were processed in automated tissue processor for dehydration, clearing, and paraffin embedding. Section were cut in rotary microtome at 4 micrometer thickness. The section was stained for Hematoxylin and Eosin stain and Geimsa overnight stain. Result: The present studyincluded 57 cases of upperGIT biopsies (gastro esophageal duodenal biopsies). The incidence of Helicobacter Pylori was seen with chronic gastritis in our study. Conclusion: H.pyloriareetiologically associated with chronic active gas triti s, duodenal ulcer, gastric ulcer, primarygastric B-cell lymphoma or mucosalassociated lymphoid type lymphoma (MALT lymphoma) and gastric adenocarcinoma. Helicobacter pylori induced chronic gas trit is were encountered in 16(47.22%) casesofthe presentstudy. Overnight Giemsa stain was done on all the patients and a histopathological diagnosis was made along with the study of the incidence of Helicobacterpylori positivity in all these patients.
- Published
- 2018
34. Silicate weathering and carbon cycle controls on the Oligocene-Miocene transition glaciation
- Author
-
Stewart, Joseph A., James, Rachael H., Anand, Pallavi, and Wilson, Paul A.
- Subjects
planktonic foraminifera ,silicate weathering ,organic carbon ,fungi ,Li/Ca ,Mi-1 - Abstract
Changes in both silicate weathering rates and organic carbon burial have been proposed as drivers of the transient “Mi-1” glaciation event at the Oligocene-Miocene transition (OMT; ~23 Ma). However detailed geochemical proxy data are required to test these hypotheses. Here we present records of Li/Ca, Mg/Ca, Cd/Ca, U/Ca, δ18O, δ13C, and shell weight in planktonic foraminifera from marine sediments spanning the OMT in the equatorial Atlantic Ocean. Li/Ca values increase by 1 μmol/mol across this interval. We interpret this to indicate a ~20% increase in silicate weathering rates, which would have lowered atmospheric CO2, potentially forcing the Antarctic glaciation circa 23 Ma. δ13C of thermocline dwelling planktonic foraminifera track the global increase in seawater δ13C across the OMT and during the Mi-1 event, hence supporting a hypothesized global increase in organic carbon burial rates. High δ13C previously measured in epipelagic planktonic foraminifera and high Cd/Ca ratios during Mi-1 are interpreted to represent locally enhanced primary productivity, stimulated by increased nutrients supply to surface waters. The fingerprint of high export production and associated organic carbon burial at this site is found in reduced bottom water oxygenation (inferred from high foraminiferal U/Ca), and enhanced respiratory dissolution of carbonates, characterised by reduced foraminiferal shell weight. Replication of our results elsewhere would strengthen the case that weathering-induced CO2 sequestration preconditioned climate for Antarctic ice sheet growth across the OMT and increased burial of organic carbon acted as a feedback that intensified cooling at this time.
- Published
- 2017
- Full Text
- View/download PDF
35. Inter-comparison of antimicrobial photodynamic therapy, LASER, and an antifungal agent as adjunct intracanal irrigation techniques to standard disinfection protocols in reducing counts in the root canals of primary teeth: A pilot study.
- Author
-
Anand, Pallavi, Mathur, Shivani, Sachdev, Vinod, and Jain, Anshi
- Abstract
Background: Despite endodontic infections being a common problem in the primary dentition, some of the infected primary teeth can remain functional until the exfoliation through endodontic treatment. The primary endodontic treatment goal must be to optimize root canal disinfection and to prevent reinfection.Aim: The aim of this study is to compare the antifungal efficacy of antimicrobial photodynamic therapy, LASER, and 1% clotrimazole as irrigants by reducing the colony-forming units (CFU) of Candida albicans in the infected root canals of primary teeth.Materials and Methods: Pulp therapy was performed on deciduous mandibular second molars of 20 healthy children aged 5-8 years, which were divided into four groups of intracanal disinfection protocols: Group 1 (n = 5) - Sodium Hypochlorite, Group 2 (n = 5) - Photodynamic, Group 3 (n = 5) - Normal saline with LASER, and Group 4 - (n = 5) Antifungal. Disinfection potential was compared by collecting samples one just after access opening and the other after the experimental groups using paper points. The samples were cultured and incubated for 48 h to check change in CFU of the fungi.Results: Data were analyzed statistically using the Shapiro-Wilk's test, Mann-Whitney U-test; Kruskal-Wallis test, and Wilcoxon signed-ranks test. No significant difference (P > 0.05) was found between the different groups. However, complete inhibition of C. albicans CFU was seen with Group 4.Conclusion: One percent Clotrimazole (antifungal) can be utilized as an adjunct in the endodontic irrigation protocol for better success of pulpectomy in children. [ABSTRACT FROM AUTHOR]- Published
- 2020
- Full Text
- View/download PDF
36. Comparison and detection the level of C Reactive Protein in different age groups on patients of Rheumatoid Arthritis at tertiary care centre of Kanpur (U.P.)
- Author
-
Gupta, Parul, Anand, Pallavi, Kumar, Shrawan, Sujatha, R, Gupta, Parul, Anand, Pallavi, Kumar, Shrawan, and Sujatha, R
- Abstract
Background: C-reactive protein (CRP) is a phylogenetically highly conserved plasma protein, with homologous in vertebrates and many invertebrates that participate in the systemic response to inflammation. So the significance of this study is to detect the levels of CRP in RA patients and its association with different age groups. Objectives: 1. To detect the levels of CRP in RA patients. 2. To compare the CRP levels in different age groups. Material and Methods: A hospital based study was conducted among 180 rheumatoid arthritis patients who attended the medicine OPD in 1 year. A predesigned questionnaire was used to collect the particulars of the patient. 5ml blood sample was collected from patients after informed consent. CRP levels were detected by semi-quantitative method. Appropriate statistical methods were used for defining the objectives. Epi info software was used for analysis purpose. Results: as the age increases the CRP levels increases (2.960.816, CI= 2.78-3.14) for the age group of 20-40 years. And (3.120.932, CI= 3.02-3.39) for 41-60 and above. Also the level of CRP increases it is considered only in mild category. Conclusion: Proper investigation during the signs and symptoms must be done. As CRP increases with age all the necessary prevention and diagnostic techniques must be used.
- Published
- 2017
37. Influence of the Amazon River on the Nd isotope composition of deep water in the western equatorial Atlantic during the Oligocene-Miocene transition
- Author
-
Stewart, Joseph, Gutjahr, Marcus, James, Rachael, Anand, Pallavi, and Wilson, Paul
- Subjects
Geophysics ,Space and Planetary Science ,Geochemistry and Petrology ,fish teeth ,foraminifera ,ODP Site 926 ,Earth and Planetary Sciences (miscellaneous) ,neodymium isotopes ,Oligocene–Miocene ,Amazon - Abstract
Highlights • Records of seawater εNdεNd are highly unradiogenic across the OMT at Ceara Rise. • Strong influence of Amazon particulate Nd on seawater εNdεNd at Ceara Rise. • Point-sourced riverine Nd influences seawater far from continental shelf. • Regional sedimentary Nd flux can be confused with water mass mixing signals. Abstract Dissolved and particulate neodymium (Nd) are mainly supplied to the oceans via rivers, dust, and release from marine sediments along continental margins. This process, together with the short oceanic residence time of Nd, gives rise to pronounced spatial gradients in oceanic 143Nd/144Nd ratios (εNdεNd). However, we do not yet have a good understanding of the extent to which the influence of riverine point-source Nd supply can be distinguished from changes in mixing between different water masses in the marine geological record. This gap in knowledge is important to fill because there is growing awareness that major global climate transitions may be associated not only with changes in large-scale ocean water mass mixing, but also with important changes in continental hydroclimate and weathering. Here we present εNdεNd data for fossilised fish teeth, planktonic foraminifera, and the Fe–Mn oxyhydroxide and detrital fractions of sediments recovered from Ocean Drilling Project (ODP) Site 926 on Ceara Rise, situated approximately 800 km from the mouth of the River Amazon. Our records span the Mi-1 glaciation event during the Oligocene–Miocene transition (OMT; ∼23 Ma). We compare our εNdεNd records with data for ambient deep Atlantic northern and southern component waters to assess the influence of particulate input from the Amazon River on Nd in ancient deep waters at this site. εNdεNd values for all of our fish teeth, foraminifera, and Fe–Mn oxyhydroxide samples are extremely unradiogenic (εNd≈−15εNd≈−15); much lower than the εNdεNd for deep waters of modern or Oligocene–Miocene age from the North Atlantic (εNd≈−10εNd≈−10) and South Atlantic (εNd≈−8εNd≈−8). This finding suggests that partial dissolution of detrital particulate material from the Amazon (εNd≈−18εNd≈−18) strongly influences the εNdεNd values of deep waters at Ceara Rise across the OMT. We conclude that terrestrially derived inputs of Nd can affect εNdεNd values of deep water many hundreds of kilometres from source. Our results both underscore the need for care in reconstructing changes in large-scale oceanic water-mass mixing using sites proximal to major rivers, and highlight the potential of these marine archives for tracing changes in continental hydroclimate and weathering.
- Published
- 2016
- Full Text
- View/download PDF
38. Geochemical imprints of genotypic variants of Globigerina bulloides in the Arabian Sea
- Author
-
Sadekov, Aleksey Yu., Darling, Kate F., Ishimura, Toyoho, Wade, Christopher M., Kimoto, Katsunori, Singh, Arun Deo, Anand, Pallavi, Kroon, Dick, Jung, Simon, Ganssen, Gerald, Ganeshram, Raja, Tsunogai, Urumu, Elderfield, Henry, Earth and Climate, and University of St Andrews. School of Geography and Geosciences
- Subjects
GC ,Palaeontology ,NDAS ,G Geography (General) ,Mg/Ca thermometry ,Oceanography ,proxy reconstructions ,planktonic foraminifera ,G1 ,genetic variability ,paleoclimate ,GC Oceanography ,SDG 14 - Life Below Water ,SDG 2 - Zero Hunger ,geochemistry - Abstract
The molecular work was funded by an Advanced Fellowship award to K. Darling (UK Natural Environment Research Council (NERC); NER/J/S/2000/00860 and NE/D009707/1). This work was also supported by European Research Council (ERC) through a research grant to H. Elderfield. A.D.S. acknowledges support from the Indian Space Research Organization through an ISRO-GBP grant sanctioned in 2008. P. Anand is thankful for NERC support (NE/I019891/1). Planktonic foraminifera record oceanic conditions in their shell geochemistry. Many palaeoenvironmental studies have used fossil planktonic foraminifera to constrain past seawater properties by defining species based on their shell morphology. Recent genetic studies, however, have identified ecologically distinct genotypes within traditionally recognized morphospecies, signaling potential repercussions for palaeoclimate reconstructions. Here we demonstrate how the presence of Globigerina bulloides cryptic genotypes in the Arabian Sea may influence geochemical signals of living and fossil assemblages of these morphospecies. We have identified two distinct genotypes of G. bulloides with either cool water (type-II) or warm water (type-I) temperature preferences in the Western Arabian Sea. We accompany these genetic studies with analyses of Mg/Ca and stable oxygen isotope (δ18O) compositions of individual G. bulloides shells. Both Mg/Ca and δ18O values display bimodal distribution patterns. The distribution of Mg/Ca values cannot be simply explained by seawater parameters, and we attribute it to genotype-specific biological controls on the shell geochemistry. The wide range of δ18O values in the fossil assemblage also suggests that similar controls likely influence this proxy in addition to environmental parameters. However, the magnitude of this effect on the δ18O signals is not clear from our data set, and further work is needed to clarify this. We also discuss current evidence of potential genotype-specific geochemical signals in published data on G. bulloides geochemistry and other planktonic foraminiferal species. We conclude that significant caution should be taken when utilizing G. bulloides geochemistry for paleoclimate reconstruction in the regions with upwelling activity or oceanographic fronts. Publisher PDF
- Published
- 2016
- Full Text
- View/download PDF
39. Influence of the Amazon River on the Nd isotope composition of deep water in the western equatorial Atlantic during the Oligocene–Miocene transition
- Author
-
Stewart, Joseph A., Gutjahr, Marcus, James, Rachael H., Anand, Pallavi, Wilson, Paul A., Stewart, Joseph A., Gutjahr, Marcus, James, Rachael H., Anand, Pallavi, and Wilson, Paul A.
- Abstract
Highlights • Records of seawater εNdεNd are highly unradiogenic across the OMT at Ceara Rise. • Strong influence of Amazon particulate Nd on seawater εNdεNd at Ceara Rise. • Point-sourced riverine Nd influences seawater far from continental shelf. • Regional sedimentary Nd flux can be confused with water mass mixing signals. Abstract Dissolved and particulate neodymium (Nd) are mainly supplied to the oceans via rivers, dust, and release from marine sediments along continental margins. This process, together with the short oceanic residence time of Nd, gives rise to pronounced spatial gradients in oceanic 143Nd/144Nd ratios (εNdεNd). However, we do not yet have a good understanding of the extent to which the influence of riverine point-source Nd supply can be distinguished from changes in mixing between different water masses in the marine geological record. This gap in knowledge is important to fill because there is growing awareness that major global climate transitions may be associated not only with changes in large-scale ocean water mass mixing, but also with important changes in continental hydroclimate and weathering. Here we present εNdεNd data for fossilised fish teeth, planktonic foraminifera, and the Fe–Mn oxyhydroxide and detrital fractions of sediments recovered from Ocean Drilling Project (ODP) Site 926 on Ceara Rise, situated approximately 800 km from the mouth of the River Amazon. Our records span the Mi-1 glaciation event during the Oligocene–Miocene transition (OMT; ∼23 Ma). We compare our εNdεNd records with data for ambient deep Atlantic northern and southern component waters to assess the influence of particulate input from the Amazon River on Nd in ancient deep waters at this site. εNdεNd values for all of our fish teeth, foraminifera, and Fe–Mn oxyhydroxide samples are extremely unradiogenic (εNd≈−15εNd≈−15); much lower than the εNdεNd for deep waters of modern or Oligocene–Miocene age from the North Atlantic (εNd≈−10εNd≈−10) and South Atlantic
- Published
- 2016
40. High-precision radiogenic strontium isotope measurements of the modern and glacial ocean: Limits on glacial–interglacial variations in continental weathering
- Author
-
Mokadem, Fatima, Parkinson, Ian J., Hathorne, Ed C., Anand, Pallavi, Allen, John T., Burton, Kevin W., Mokadem, Fatima, Parkinson, Ian J., Hathorne, Ed C., Anand, Pallavi, Allen, John T., and Burton, Kevin W.
- Abstract
Highlights: • High-precision glacial–interglacial 87Sr/86Sr record from planktic foraminifera. • Major oceans yield indistinguishable 87Sr/86Sr values at ±5 ppm level of precision. • Foraminifera show no resolvable 87Sr/86Sr variation since last glacial interval. • These data accommodate a ±12% variation for the steady-state weathering flux. • A short-term weathering pulse during de-glaciation is not accommodated by the data. Abstract Existing strontium radiogenic isotope (87Sr/86Sr) measurements for foraminifera over Quaternary glacial–interglacial climate cycles provide no evidence for variations in the isotope composition of seawater at the ±9–13 ppm level of precision. However, modelling suggests that even within this level of uncertainty significant (up to 30%) variations in chemical weathering of the continents are permitted, accounting for the longer-term rise in 87Sr/86Sr over the Quaternary, and the apparent imbalance of Sr in the oceans at the present-day. This study presents very high-precision 87Sr/86Sr isotope data for modern seawater from each of the major oceans, and a glacial–interglacial seawater record preserved by planktic foraminifera from Ocean Drilling Program (ODP) Site 758 in the north-east Indian ocean. Strontium isotope 87Sr/86Sr measurements for modern seawater from the Atlantic, Pacific and Indian Oceans are indistinguishable from one another (87Sr/86Sr = 0.7091792 ± 0.0000021, n=17n=17) at the level of precision obtained in this study (±4.9 ppm 2σ). This observation is consistent with the very long residence time of Sr in seawater, and underpins the utility of this element for high precision isotope stratigraphy. The 87Sr/86Sr seawater record preserved by planktic foraminifera shows no resolvable glacial–interglacial variation (87Sr/86Sr = 0.7091784 ± 0.0000035, n=10n=10), and limits the response of seawater to variations in the chemical weathering flux and/or composition to ±4.9 ppm or less. Calculations suggest that a variation of ±12%
- Published
- 2015
41. ROLE OF HBA1C AND HS - CRP IN TYPE 2 DIABETES MELLITUS WITH CARDIOVASCULAR DISEASES
- Author
-
Anand, Pallavi, primary, Arya, Manju Lata, additional, Kumar, Vikas, additional, Jain, Renu, additional, and Jyotirmay, Jyotirmay, additional
- Published
- 2015
- Full Text
- View/download PDF
42. STUDY OF ADENOSINE DEAMINASE AND LYMPHOCYTE/ NEUTROPHIL RATIO IN C OMBINATION AS DIAGNOSTIC TOOL FOR TUBERCULAR PLEURAL EFFUSION
- Author
-
Rahman, Md. Faizur, primary, Zafar, Ezaz, additional, Prasad, Krishna Ranjan, additional, Anand, Pallavi, additional, and Arya, Manju Lata, additional
- Published
- 2015
- Full Text
- View/download PDF
43. CORRELATION OF DIETARY HABITS, PHYSICAL ACTIVITY AND HYPERTENSION IN ADMINISTRATIVE OFFICERS IN WESTERN UTTAR PRADESH
- Author
-
Arya, Manju Lata, primary, Anand, Pallavi, additional, and Kumar, Vikas, additional
- Published
- 2015
- Full Text
- View/download PDF
44. Mg/Ca and Sr/Ca ratios in planktonic foraminifera: Proxies for upper water column temperature reconstruction
- Author
-
Cléroux, Caroline, Cortijo, Elsa, Anand, Pallavi, Labeyrie, Laurent, Bassinot, Franck, Caillon, Nicolas, Duplessy, Jean-Claude, Laboratoire des Sciences du Climat et de l'Environnement [Gif-sur-Yvette] (LSCE), Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Paléocéanographie (PALEOCEAN), Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), The Open University [Milton Keynes] (OU), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), and Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)
- Subjects
[SDU.OCEAN]Sciences of the Universe [physics]/Ocean, Atmosphere ,[SDU.ENVI]Sciences of the Universe [physics]/Continental interfaces, environment - Abstract
International audience; [1] Reliable temperature estimates from both surface and subsurface ocean waters are needed to reconstruct past upper water column temperature gradients and past oceanic heat content. This work examines the relationships between trace element ratios in fossil shells and seawater temperature for surface-dwelling foraminifera species, Globigerinoides ruber (white) and Globigerina bulloides, and deep-dwelling species, Globorotalia inflata, Globorotalia truncatulinoides (dextral and sinistral) and Pulleniatina obliquiloculata. Mg/Ca and Sr/Ca ratios in shells picked in 29 modern core tops from the North Atlantic Ocean are calibrated using calculated isotopic temperatures. Mg/Ca ratios on G. ruber and G. bulloides agree with published data and relationships. For deep-dwelling species, Mg/Ca calibration follows the equation Mg/Ca = 0.78 (±0.04) Â exp (0.051 (±0.003) Â T) with a significant correlation coefficient of R 2 = 0.74. Moreover, there is no significant difference between the different deep-dwellers analyzed. For the Sr/Ca ratio, the surface dwellers and P. obliquiloculata do not record any temperature dependence. For the Globorotalia species, the thermo dependence of Sr/Ca ratio can be described by a single linear relationship: Sr/Ca = (0.0182 (±0.001) Â T) + 1.097 (±0.018), R 2 = 0.85. Temperature estimates with a 1 sigma error of ±2.0°C and ±1.3°C can be derived from the Mg/Ca and Sr/Ca ratios, respectively, as long as the Sr geochemistry in the ocean has been constant through time. Citation: Cléroux, C., E. Cortijo, P. Anand, L. Labeyrie, F. Bassinot, N. Caillon, and J.-C. Duplessy (2008), Mg/Ca and Sr/Ca ratios in planktonic foraminifera: Proxies for upper water column temperature reconstruction, Paleoceanography, 23, PA3214
- Published
- 2008
- Full Text
- View/download PDF
45. An evaluation of controls on planktonic foraminiferal Sr/Ca : comparison of water column and core-top data from a North Atlantic transect
- Author
-
Mortyn, P. Graham, Elderfield, Henry, Anand, Pallavi, and Greaves, Mervyn
- Subjects
Planktonic foraminifera ,Trace elements ,Paleotemperature reconstruction - Abstract
Sr/Ca in planktonic foraminifera recovered from the water column over 0-800 m along a meridional transect in the North Atlantic Ocean from 30° to 60°N were compared with data from core-top samples on the same transect and with in situ temperatures determined from water column CTD profiles. Species belonging to the globorotaliid genus show significant variability in Sr/Ca from place to place, whereas non-globorotaliid species show no significant variability. This variability for the globorotaliid species in core-top samples has already been shown to covary with calcification temperature derived from δ¹⁸O, but it also covaries with bottom depth (symptomatic of a dissolution artifact). These alternatives are distinguishable from the water column data for which the globorotaliid species show a small temperature dependence of 0.025 mmol/mol/°C within the range 5-15°C. However, temperature dependence is not supported by glacial-interglacial differences in Sr/Ca for globorotaliid and non-globorotaliid species, and at least from this perspective, a [CO₃²⁻] influence seems more likely.
- Published
- 2005
46. Calibration of Mg/Ca thermometry in planktonic foraminifera from a sediment trap time series
- Author
-
Anand, Pallavi, Elderfield, Henry, Conte, Maureen H, and Marine Biogeology
- Abstract
Paired Mg/Ca and δ18O measurements on planktonic foraminiferal species (G. ruber white, G. ruber pink, G. sacculifer, G. conglobatus, G. aequilateralis, O. universa, N. dutertrei, P. obliquiloculata, G. inflata, G. truncatulinoides, G. hirsuta, and G. crassaformis) from a 6-year sediment trap time series in the Sargasso Sea were used to define the sensitivity of foraminiferal Mg/Ca to calcification temperature. Habitat depths and calcification temperatures were estimated from comparison of δ18O of foraminifera with equilibrium calcite, based on historical temperature and salinity data. When considered together, Mg/Ca (mmol/mol) of all species, except two, show a significant (r = 0.93) relationship with temperature (T °C) of the form Mg/Ca = 0.38 (±0.02) exp 0.090 (±0.003)T, equivalent to a 9.0 ± 0.3% change in Mg/Ca for a 1°C change in temperature. Small differences exist in calibrations between species and between different size fractions of the same species. O. universa and G. aequilateralis have higher Mg/Ca than other species, and in general, data can be best described with the same temperature sensitivity for all species and pre-exponential constants in the sequence O. universa > G. aequilateralis ≈ G. bulloides > G. ruber ≈ G. sacculifer ≈ other species. This approach gives an accuracy of ±1.2°C in the estimation of calcification temperature. The ∼9% sensitivity to temperature is similar to published studies from culture and core top calibrations, but differences exist from some literature values of pre-exponential constants. Different cleaning methodologies and artefacts of core top dissolution are probably implicated, and perhaps environmental factors yet understood. Planktonic foraminiferal Mg/Ca temperature estimates can be used for reconstructing surface temperatures and mixed and thermocline temperatures (using G. ruber pink, G. ruber white, G. sacculifer, N. dutertrei, P. obliquiloculata, etc.). The existence of a single Mg thermometry equation is valuable for extinct species, although use of species-specific equations will, where statistically significant, provide more accurate evaluation of Mg/Ca paleotemperature.
- Published
- 2003
- Full Text
- View/download PDF
47. Geochemical assessment of the palaeoecology, ontogeny, morphotypic variability and palaeoceanographic utility of “Dentoglobigerina” venezuelana
- Author
-
Stewart, Joseph A., Wilson, Paul A., Edgar, Kirsty M., Anand, Pallavi, James, Rachael H., Stewart, Joseph A., Wilson, Paul A., Edgar, Kirsty M., Anand, Pallavi, and James, Rachael H.
- Abstract
To better understand the links between the carbon cycle and changes in past climate over tectonic timescales we need new geochemical proxy records of secular change in silicate weathering rates. A number of proxies are under development, but some of the most promising (e.g. palaeoseawater records of Li and Nd isotope change) can only be employed on such large samples of mono-specific foraminifera that application to the deep sea sediment core archive becomes highly problematic. “Dentoglobigerina” venezuelana presents a potentially attractive target for circumventing this problem because it is a typically large (> 355 μm diameter), abundant and cosmopolitan planktic foraminifer that ranges from the early Oligocene to early Pliocene. Yet considerable taxonomic and ecological uncertainties associated with this taxon must first be addressed. Here, we assess the taxonomy, palaeoecology, and ontogeny of “D.” venezuelana using stable isotope (oxygen and carbon) and Mg/Ca data measured in tests of late Oligocene to early Miocene age from Ocean Drilling Program (ODP) Site 925, on Ceara Rise, in the western equatorial Atlantic. To help constrain the depth habitat of “D.” venezuelana relative to other species we report the stable isotope composition of selected planktic foraminifera species within Globigerina, Globigerinoides, Paragloborotalia and Catapsydrax. We define three morphotypes of “D.” venezuelana based on the morphology of the final chamber and aperture architecture. We determine the trace element and stable isotope composition of each morphotype for different size fractions, to test the validity of pooling these morphotypes for the purposes of generating geochemical proxy datasets and to assess any ontogenetic variations in depth habitat. Our data indicate that “D.” venezuelana maintains a lower thermocline depth habitat at Ceara Rise between 24 and 21 Ma. Comparing our results to published datasets we conclude that this lower thermocline depth ecology for the Olig
- Published
- 2012
48. Influence of the Indian Summer Monsoon runoff on marine productivity during middle Pliocene-early Pleistocene in the northwestern Bay of Bengal.
- Author
-
Romero, Oscar E., Bokahri-Friberg, Yasmin, and Anand, Pallavi
- Published
- 2019
49. You Can’t Climb a Broken Ladder: Examining Underrepresentation of Multiply-Disadvantaged Groups in Secure and Senior Roles in UK Geochemistry
- Author
-
Anand, Pallavi, Bots, Pieter, Gagnon, Jessica, Appiah, Francis, Maters, Elena, Bhagwat, Shonil, Little, Susan, Riches, Amy, ChiFru, Ernest, Lawrence, Anya, Ngwenya, Bryne, Anand, Pallavi, Bots, Pieter, Gagnon, Jessica, Appiah, Francis, Maters, Elena, Bhagwat, Shonil, Little, Susan, Riches, Amy, ChiFru, Ernest, Lawrence, Anya, and Ngwenya, Bryne
- Abstract
Geochemistry provides useful research tools related to fundamental processes in Earth, Environmental and Planetary Sciences. It has a distinct identity among the academic communities in these subjects, yet there is no specific data on workforce diversity among geochemists. We present the first demographic data of UK geochemists from a voluntary anonymous survey. We scrutinise the data with respect to protected characteristics (e.g., age, ethnicity, gender identity, sexual orientation and disability) and seniority of those within the community. We furthermore use this UK data to compare the career progression of geochemists who belong to multiply-privileged identities with those who belong to multiply-disadvantaged identities, to assess their representations with increased seniority on the academic career. This UK based case study on diversity and inclusion suggests that the career paths of geochemists belonging to multiple disadvantaged groups are restricted, including overrepresentation among those on fixed-term contracts or in service roles for laboratory support. Our data highlight that there is a decrease in diversity with an increase in seniority; specifically, UK geochemists from sexual and gender minorities, neurodiverse, and women from ethnic minority groups were not represented among the participants of our survey at the top of the academic ladder. There are many reasons for the loss of diversity in the UK geochemistry community with increased seniority. In order to address this and the underrepresentation of particular groups in senior leadership roles, our findings suggest that the career progression of geochemists requires an intersectional lens to examine the complexity of identity data. Such an approach would enable a better understanding of the impact of multiple and compounded disadvantages, biases, negative experiences and discrimination faced by multiply-disadvantaged identities.
50. You can't climb a broken ladder: Examining underrepresentation of multiply-disadvantaged groups in secure and senior roles in UK geochemistry
- Author
-
Anand, Pallavi, Bots, Pieter, Gagnon, Jessica, Appiah, Francis, Matera, Elena, Bhagwat, Shonil, Little, Susan, Riches, Amy, ChiFru, Ernest, Lawrence, Anya, Ngwenya, Bryne, Anand, Pallavi, Bots, Pieter, Gagnon, Jessica, Appiah, Francis, Matera, Elena, Bhagwat, Shonil, Little, Susan, Riches, Amy, ChiFru, Ernest, Lawrence, Anya, and Ngwenya, Bryne
- Abstract
Geochemistry provides useful research tools related to fundamental processes in Earth, Environmental and Planetary Sciences. It has a distinct identity among the academic communities in these subjects, yet there is no specific data on workforce diversity among geochemists. We present the first demographic data of UK geochemists from a voluntary anonymous survey. We scrutinise the data with respect to protected characteristics (e.g., age, ethnicity, gender identity, sexual orientation and disability) and seniority of those within the community. We furthermore use this UK data to compare the career progression of geochemists who belong to multiply-privileged identities with those who belong to multiply-disadvantaged identities, to assess their representations with increased seniority on the academic career. This UK based case study on diversity and inclusion suggests that the career paths of geochemists belonging to multiple disadvantaged groups are restricted, including overrepresentation among those on fixed-term contracts or in service roles for laboratory support. Our data highlight that there is a decrease in diversity with an increase in seniority; specifically, UK geochemists from sexual and gender minorities, neurodiverse, and women from ethnic minority groups were not represented among the participants of our survey at the top of the academic ladder. There are many reasons for the loss of diversity in the UK geochemistry community with increased seniority. In order to address this and the underrepresentation of particular groups in senior leadership roles, our findings suggest that the career progression of geochemists requires an intersectional lens to examine the complexity of identity data. Such an approach would enable a better understanding of the impact of multiple and compounded disadvantages, biases, negative experiences and discrimination faced by multiply-disadvantaged identities.
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.