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When the lens of the 5-day chick embryo is surgically reversed so that its epithelium faces the neural retina the elongation of those lens cells which have already differentiated is arrested and the epithelial cells differentiate into a new set of lens fibers. This internal reorganization, together with a reversal in polarity at the lens equator, results in a complete reversal of the polarity of the-entire lens.

The embryonic chick corneal epithelium produces a highly structured acellular matrix beneath its basal surface during early development. This matrix, which contains collagen, serves as a morphogenetic template for subsequent stromal development in that the three-dimensional architecture of the adult corneal stroma is initially established, in miniature, in this epithelially derived connective tissue. Examination of the early corneal epithelium and matrix in both the light and electron microscope suggests that self assembly of the matrix may be one of several important factors in the morphogenesis of this early connective tissue.

A method is described for maintaining long term infusions of fluids into the chorioallantoic circulation of the embryo of the domestic fowl. Infusions can be continued up to 4 days in 6- to 17-day-old chicks, with subsequent hatching.

Influence of Mouse Neural Retina on Regeneration of Chick Neural Retina from Chick Embryonic Pigmented Epithelium