133 results on '"AlAmari A"'
Search Results
2. Dynamic Patterns and Predominance of Respiratory Pathogens Post-COVID-19: Insights from a Two-Year Analysis
- Author
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Salma AlBahrani, Samira Jamaan AlZahrani, Thekra N. Al-Maqati, Atheer Almehbash, Anfal Alshammari, Refan Bujlai, Sarah Ba Taweel, Fares Almasabi, Abdullah AlAmari, and Jaffar A. Al-Tawfiq
- Subjects
COVID-19 ,Respiratory pathogens ,RSV ,Influenza ,SARS-CoV-2 ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Introduction Respiratory tract infections (RTIs) stand out as the most frequent causes leading to visits to the emergency department and hospitalizations. This study aims to assess the types and prevalence of respiratory infections across two years following the end of the COVID-19 pandemic. Methods Patients presenting with an influenza-like illness (ILI) were tested using multiplex RT-PCR (QIAstat-Dx, Qiagen). The multiplexed RT- PCR test detects 21 respiratory viruses and bacteria. Results During the study period, PCR test was done on a total of 1,790 samples were tested, and 712 (40%) were positive for a total of 796 pathogens. The mean age (± SD) of the participants was 20.1 ± 28.4 years in 2022 and 21.9 ± 27.6 years in 2023. Among the detected pathogens, the most prevalent were Rhinovirus/Enterovirus 222 (12.4%), followed by RSV A&B (103 cases, 5.7%), and H1N1 Influenza (77 cases, 4.3%). Additionally, Influenza A/B constituted 172 (9.6%) while parainfluenza constituted (58, 3.2%). SARS-CoV-2 was identified in 3.97% of the samples. Over the two-year period, the monthly pattern of the identified pathogens exhibited fluctuations in the prevalence. Furthermore, variations were observed in the detected pathogens across different age groups. Conclusion In addition to adding significant knowledge to the field of respiratory viral infections, this study emphasizes the necessity of ongoing research and surveillance for the detection and characterization of respiratory viruses, particularly those with the potential for emergence. Such studies would also require setting up a strategy for genotyping and/or sequencing of viruses.
- Published
- 2024
- Full Text
- View/download PDF
3. Local linear estimation for the censored functional regression
- Author
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Fatimah A Almulhim, Torkia Merouan, Mohammed B. Alamari, and Boubaker Mechab
- Subjects
regression function ,functional data ,asymptotic normality ,local linear estimation ,kaplan-meier estimator ,Mathematics ,QA1-939 - Abstract
This work considers the Local Linear Estimation (LLE) of the conditional functional mean. This regression model is used when the independent variable is functional, and the dependent one is a censored scalar variable. Under standard postulates, we establish the asymptotic distribution of the LLE by proving its asymptotic normality. The obtained results show the superiority of the LLE approach over the functional local constant one. The feasibility of the studied model is demonstrated using artificial data. Finally, the usefulness of the obtained asymptotic distribution in incomplete functional data is highlighted through a real data application.
- Published
- 2024
- Full Text
- View/download PDF
4. Fighting eimeriosis by using the anti-eimerial and anti-apoptotic properties of rhatany root extract
- Author
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Saleh Al-Quraishy, Rewaida Abdel-Gaber, Ghada Alamari, Andreas Meryk, Saeed El-Ashram, Esam M. Al-Shaebi, and Mohamed A. Dkhil
- Subjects
Rhatany ,Eimeria papillata ,coccidiostats ,apoptosis ,goblet cells ,mice ,Immunologic diseases. Allergy ,RC581-607 - Abstract
BackgroundOver the last decade, extensive use of coccidiostats to treat and control Eimeria infection has developed drug resistance, prompting the search for new alternative therapies. Rhatany is proven to have various pharmacological properties.ObjectiveThe present study aimed to in vitro and in vivo evaluate the effect of Rhatany roots extract (RRE) as an anti-eimerial and anti-apoptotic agent against murine eimeriosis induced by Eimeria papillata.MethodsPhytochemical screening by gas chromatography-mass spectrometry analysis (GC-MS) was used to detect active compounds in RRE. In vitro anti-eimerial activity of RRE (200, 100, 50 mg/ml), amprolium, phenol, Dettol™, and formalin were studied after incubation with non-sporulated Eimeria oocysts. For the in vivo study, twenty-five male C57BL/6 mice were randomly allocated into five groups. Animals in the first group were just given distilled H2O, while those in the second group were given 200 mg/kg RRE for 5 days. The Eimeria parasite’s oocysts were infected into the third, fourth, and fifth groups. For treatment, RRE (200 mg/kg) and amprolium (120 mg/kg) were orally given to the 4th and 5th groups for five days, respectively. All mice were euthanized, on day 5 post-infection, to collect the jejunal tissues under study. Investigations were undertaken into the oocyst output in feces and goblet cells in mice jejuna. Assays for glutathione peroxidase (GPx), hydrogen peroxide (H2O2), and myeloperoxidase (MPO) were also performed. In jejunal tissue, cysteine aspartic acid protease-3 (Caspase-3) was counted using immunohistochemistry, while BCL2-associated X protein (Bax) and B-cell lymphoma-2 (BCL-2) were assayed using ELISA. In addition, mRNA expression of the goblet cell response gene (MUC2) was detected using real-time PCR.ResultsPhytochemical screening by GC-MS demonstrated the presence of 22 compounds in the RRE. The in vitro study revealed that RRE significantly inhabited the oocyst sporulation in a dose-dependent manner. By day 5 after infection with the Eimeria parasite, the number of oocysts in mice feces was significantly reduced after RRE treatment (1.308 × 106 ± 1.36 × 105 oocysts/g feces) compared to the infected group (5.387 × 106 ± 4.29 × 105 oocysts/g feces). Moreover, the Eimeria infection reduced the number of goblet cells of mice jejuna and its specific gene, MUC2. The treatment with RRE increased the number of goblet cells/villus from 3.45 ± 0.17 to 6.04 ± 0.23, associated with upregulation for MUC2 from 0.26 to 2.39-fold. Also, the Eimeria experimental infection lowered the activity of the antioxidant enzyme represented by GPx (23.99 ± 3.68 mg/g tissue), while increasing the stress parameters of hydrogen peroxide (0.07 ± 0.01 mM/g) as well as the activity of MPO (66.30 ± 3.74 U/mg). The production of apoptotic markers including Caspase-3 (68.89 ± 2.67 U/g) and Bax (159.05 ± 6.50 pg/ml) was significantly elevated while decreasing the anti-apoptotic marker of BCL2 (0.42 ± 0.07 pg/ml). Our study proved that RRE significantly reduced oxidative stress, and apoptotic markers as well as the inflammatory activity of MPO. Also, antioxidant enzyme and anti-apoptotic activity in the jejunum of E. papillata-infected mice were enhanced after RRE treatment.ConclusionOur study highlights the potential of RRE as a natural solution for coccidiosis management by modulating apoptosis in E. papillata host cells. However, further research is needed to fully understand the underlying mechanisms and enhance our understanding of its therapeutic efficacy.
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- 2024
- Full Text
- View/download PDF
5. Krameria lappacea root extract’s anticoccidial properties and coordinated control of CD4 T cells for IL-10 production and antioxidant monitoring
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Rewaida Abdel-Gaber, Ghada Alamari, Mohamed A. Dkhil, Andreas Meryk, Esam M. Al-Shaebi, and Saleh Al-Quraishy
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Eimeria papillata ,oxidative damage ,Krameria lappacea ,CD4 T cells ,NFkB cells ,IL-10 ,Immunologic diseases. Allergy ,RC581-607 - Abstract
IntroductionRecently, the use of botanicals as an alternative to coccidiostats has been an appealing approach for controlling coccidiosis. Therefore, this study was conducted to evaluate the potential role of aqueous methanolic extract (200 mg/kg) of Krameria lappacea (roots) (KLRE) against infection induced by Eimeria papillata.MethodsA total of 25 male C57BL/6 mice were divided into five groups (I, II, III, IV, and V). On 1st day of the experiment, all groups except groups I (control) and II (non-infected-treated group with KLRE), were inoculated orally with 103 sporulated E. papillata oocysts. On the day of infection, group IV was treated with KLRE. Group V served as an infected-treated group and was treated with amprolium (coccidiostat).ResultsTreatment with extract and coccidiostat was continued for five consecutive days. While not reaching the efficacy level of the reference drug (amprolium), KLRE exhibited notable anticoccidial activity as assessed by key criteria, including oocyst suppression rate, total parasitic stages, and maintenance of nutrient homeostasis. The presence of phenolic and flavonoid compounds in KLRE is thought to be responsible for its positive effects. The Eimeria infection increased the oxidative damage in the jejunum. KLRE treatment significantly increased the activity of catalase and superoxide dismutase. On the contrary, KLRE decreased the level of malondialdehyde and nitric oxide. Moreover, KLRE treatment decreased macrophage infiltration in the mice jejunal tissue, as well as the extent of CD4 T cells and NFkB. E. papillata caused a state of systemic inflammatory response as revealed by the upregulation of inducible nitric oxide synthase (iNOs)-mRNA. Upon treatment with KLRE, the activity of iNOs was reduced from 3.63 to 1.46 fold. Moreover, KLRE was able to downregulate the expression of pro-inflammatory cytokines interferon-γ, nuclear factor kappa B, and interleukin-10 -mRNA by 1.63, 1.64, and 1.38 fold, respectively. Moreover, KLRE showed a significant reduction in the expression of IL-10 protein level from 104.27 ± 8.41 pg/ml to 62.18 ± 3.63 pg/ml.ConclusionCollectively, K. lappacea is a promising herbal medicine that could ameliorate the oxidative stress and inflammation of jejunum, induced by E. papillata infection in mice.
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- 2024
- Full Text
- View/download PDF
6. k-Nearest Neighbors Estimator for Functional Asymmetry Shortfall Regression
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Mohammed B. Alamari, Fatimah A. Almulhim, Zoulikha Kaid, and Ali Laksaci
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kNN estimator ,complete consistency ,expectile regression ,expected shortfall ,financial data ,conditional quantile ,Mathematics ,QA1-939 - Abstract
This paper deals with the problem of financial risk management using a new expected shortfall regression. The latter is based on the expectile model for financial risk-threshold. Unlike the VaR model, the expectile threshold is constructed by an asymmetric least square loss function. We construct an estimator of this new model using the k-nearest neighbors (kNN) smoothing approach. The mathematical properties of the constructed estimator are stated through the establishment of the pointwise complete convergence. Additionally, we prove that the constructed estimator is uniformly consistent over the nearest neighbors (UCNN). Such asymptotic results constitute a good mathematical support of the proposed financial risk process. Thus, we examine the easy implantation of this process through an artificial and real data. Our empirical analysis confirms the superiority of the kNN-approach over the kernel method as well as the superiority of the expectile over the quantile in financial risk analysis.
- Published
- 2024
- Full Text
- View/download PDF
7. Non-Invasive Brain Sensing Technologies for Modulation of Neurological Disorders
- Author
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Salman Alfihed, Majed Majrashi, Muhammad Ansary, Naif Alshamrani, Shahad H. Albrahim, Abdulrahman Alsolami, Hala A. Alamari, Adnan Zaman, Dhaifallah Almutairi, Abdulaziz Kurdi, Mai M. Alzaydi, Thamer Tabbakh, and Faisal Al-Otaibi
- Subjects
non-invasive brain sensing ,brain neuromodulation techniques ,closed-loop neuromodulation systems ,Biotechnology ,TP248.13-248.65 - Abstract
The non-invasive brain sensing modulation technology field is experiencing rapid development, with new techniques constantly emerging. This study delves into the field of non-invasive brain neuromodulation, a safer and potentially effective approach for treating a spectrum of neurological and psychiatric disorders. Unlike traditional deep brain stimulation (DBS) surgery, non-invasive techniques employ ultrasound, electrical currents, and electromagnetic field stimulation to stimulate the brain from outside the skull, thereby eliminating surgery risks and enhancing patient comfort. This study explores the mechanisms of various modalities, including transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS), highlighting their potential to address chronic pain, anxiety, Parkinson’s disease, and depression. We also probe into the concept of closed-loop neuromodulation, which personalizes stimulation based on real-time brain activity. While we acknowledge the limitations of current technologies, our study concludes by proposing future research avenues to advance this rapidly evolving field with its immense potential to revolutionize neurological and psychiatric care and lay the foundation for the continuing advancement of innovative non-invasive brain sensing technologies.
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- 2024
- Full Text
- View/download PDF
8. Strong Consistency of Incomplete Functional Percentile Regression
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Mohammed B. Alamari, Fatimah A. Almulhim, Ouahiba Litimein, and Boubaker Mechab
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functional data ,risk analysis ,complete convergence ,quantile regression ,bandwidth parameter ,kernel method ,Mathematics ,QA1-939 - Abstract
This paper analyzes the co-fluctuation between a scalar response random variable and a curve regressor using quantile regression. We focus on the situation wherein the output variable is observed with random missing. For this incomplete functional data situation, we estimate the quantile regression by combining two principal nonparametric methods: the local linearity approach (LLA) and the kernel nearest neighbor (KNN) algorithm. We study the asymptotic properties of the constructed estimator by establishing, under general assumptions, uniform consistency over the number of neighborhoods. This asymptotic result provides good mathematical support for the selection of the optimal neighborhood. We examine the feasibility of the constructed estimator using artificially generated data. Moreover, we apply the quantile regression technique in food quality by predicting the riboflavin quantity in yogurt using spectrometry data.
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- 2024
- Full Text
- View/download PDF
9. Does Adenoid Hypertrophy Increase the Risk of Orbital Complication in Children with Acute Sinusitis?
- Author
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Almahboob, Ayshah, Alhussien, Ahmed, AlAmari, Kholoud, Khan, Adeena, AlFaky, Yasser, and Alsaleh, Saad
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- 2022
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10. Dialog System Technology Challenge 7
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Yoshino, Koichiro, Hori, Chiori, Perez, Julien, D'Haro, Luis Fernando, Polymenakos, Lazaros, Gunasekara, Chulaka, Lasecki, Walter S., Kummerfeld, Jonathan K., Galley, Michel, Brockett, Chris, Gao, Jianfeng, Dolan, Bill, Gao, Xiang, Alamari, Huda, Marks, Tim K., Parikh, Devi, and Batra, Dhruv
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Computer Science - Computation and Language - Abstract
This paper introduces the Seventh Dialog System Technology Challenges (DSTC), which use shared datasets to explore the problem of building dialog systems. Recently, end-to-end dialog modeling approaches have been applied to various dialog tasks. The seventh DSTC (DSTC7) focuses on developing technologies related to end-to-end dialog systems for (1) sentence selection, (2) sentence generation and (3) audio visual scene aware dialog. This paper summarizes the overall setup and results of DSTC7, including detailed descriptions of the different tracks and provided datasets. We also describe overall trends in the submitted systems and the key results. Each track introduced new datasets and participants achieved impressive results using state-of-the-art end-to-end technologies., Comment: This paper is presented at NIPS2018 2nd Conversational AI workshop
- Published
- 2019
11. Krameria lappacea root extract’s anticoccidial properties and coordinated control of CD4 T cells for IL-10 production and antioxidant monitoring
- Author
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Abdel-Gaber, Rewaida, primary, Alamari, Ghada, additional, Dkhil, Mohamed A., additional, Meryk, Andreas, additional, Al-Shaebi, Esam M., additional, and Al-Quraishy, Saleh, additional
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- 2024
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12. Effects of Rhazya Stricta plant organic extracts on human induced pluripotent stem cells derived neural stem cells.
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Abdullah Othman Alawad, Faisal Sultan Alagrafi, Ahmed Jaman Alfahad, Hala Abdulrahman Alamari, Fatimah Othman Alghamdi, Hussam Mokhtar Fallatah, Alhassan Hamood Aodah, Sultan Suleiman Alyousef, Muhammed Adnan Bakhrebah, Ibrahim Oqla Alanazi, and Mohannad Mokhtar Fallatah
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Medicine ,Science - Abstract
Rhazya Stricta (R. stricta) has been employed as a natural remedy for several diseases for centuries. Numerous studies revealed that R. stricta extracts contain alkaloids, tannins, and flavonoids that possess antimicrobial, anticancer, antihypertensive, and antioxidant activities. In this study, we examined the effects of organic extracts from different parts of R. stricta plant on human pluripotent stem cells (hiPSCs)-derived neural stem cells (NSCs) for medical purposes. NSCs were incubated with different concentrations of organic extracts from the leaves, stem, and fruits, and we assessed the growth and viability of the cells by using MTS assay and the chemical composition of the potential plant extract by using gas chromatography-mass spectrometry (GC/MS). Our results revealed that the methanolic extract from the stem increased NSCs growth significantly, particularly at a concentration of 25 μg/ml. GC/MS analysis was utilized to identify the potential compounds of the methanolic extract. In conclusion, our results demonstrated for the first time that methanolic stem extract of R. stricta contains compounds that can positively impact NSCs growth. These compounds can be further investigated to determine the potential bioactive compounds that can be used for research and medical purposes.
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- 2023
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13. The Catalyst behind Sri Lanka Downfall
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Muhammad Fauzan Alamari
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Sri Lanka ,Inflation ,Protectionism ,Debt ,Dependency ,Political science - Abstract
Sri Lanka shocked the world with a downfall due to an economic crisis. Among the states that had to mitigate the pandemic, Sri Lanka appears to struggle with the situation and as a result of this event, Sri Lanka is in a position of overdue debt with a total of 51 billion USD worth of debt. The inflation was created by economic shortage activity with imbalanced trade records leads to the overthrown of Sri Lanka’s president and as the result produced a vacuum of power. This paper will use of dependency theory to describe the cause of Sri Lanka’s collapse by examining several factors such as civil war, pandemic, oil price rise, and recent terrorist attack.
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- 2022
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14. Incidence of Olfactory Dysfunction in Patients with COVID-19 in a Tertiary Hospital in Saudi Arabia
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Rayan Alfallaj MBBS, Ghada AlSkait MBBS, Nouf Alamari MBBS, Lama Alfawzan MBBS, Mohammed Abualgasem MBBS, Naif H. Alotaibi MD, Ibrahim Sumaily MBBS, SB, Ibrahim Alarifi MBBS, SB, and Saad Alsaleh MBBS, FRCSC
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Otorhinolaryngology ,RF1-547 ,Immunologic diseases. Allergy ,RC581-607 - Abstract
Background Coronavirus disease (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2, a novel virus that emerged in China in December 2019. In many cases of COVID-19, olfactory dysfunction (OD) is the only symptom. Objectives This study aimed to examine the incidence of OD in patients with COVID-19 and identify an association between OD and COVID-19-related morbidity and admission. Design This was a cross-sectional study. Methods Real-time reverse transcription polymerase chain reaction-confirmed cases of COVID-19 from the Security Forces Hospital electronic registry from June 2020 to September 2020 were included in our study. Data on medical background, severity of the disease, and other related factors were collected through phone calls and electronic healthcare systems and analyzed to investigate OD in the participants. Results Of the participants, 68% had OD, with a mean recovery time of 18 days and a mean follow-up time of 129 days (76-211 days). OD was negatively correlated with admission and morbidity. Conclusion OD is a common presentation of COVID-19 and is more prevalent in mild cases of infection.
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- 2022
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15. Potential significance of medicinal plants in forensic analysis: A review
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Saqer S. Alotaibi, Doaa Alshoaibi, Hala Alamari, Sarah Albogami, Eman Khan, Areej Alshanbari, Hadeer Darwish, Bashaer Alshanqiti, Hanan Alghamdi, and Wafa Almalki
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Medicinal plants ,Forensic science ,Poisonous ,Forensic diagnostic ,Biotechnology ,Biology (General) ,QH301-705.5 - Abstract
Medicinal plants are a two-edged sword that might be exploited as a treatment specific dosage, and as deadly poisonous substances to commit murder or suicide when administered in high doses. Forensic experts can collect traces and residual materials from these toxic medicinal plants at a crime scene as forensic evidence. Further, more investigations need to be deeply implemented to in the future to understand the significance of medicinal plants in forensic investigations to detect these criminal offenses. Additionally, to provides a deep understanding of chemical substances that can impact human life positively or negatively with different doses as well as identifying the optimal or overdose concentrations for either treatments or poisonous effects using recent biotechnological approaches. This review aims to illustrate different contributions and the significance of medicinal plants in the field and further employment in the context of forensic science, especially in the Kingdom of Saudi Arabia.
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- 2021
- Full Text
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16. Fighting eimeriosis by using the anti-eimerial and anti-apoptotic properties of rhatany root extract.
- Author
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Al-Quraishy, Saleh, Abdel-Gaber, Rewaida, Alamari, Ghada, Meryk, Andreas, El-Ashram, Saeed, Al-Shaebi, Esam M., and Dkhil, Mohamed A.
- Subjects
PLANT extracts ,GAS chromatography/Mass spectrometry (GC-MS) ,GLUTATHIONE peroxidase ,HYDROGEN peroxide ,EIMERIA - Abstract
Background: Over the last decade, extensive use of coccidiostats to treat and control Eimeria infection has developed drug resistance, prompting the search for new alternative therapies. Rhatany is proven to have various pharmacological properties. Objective: The present study aimed to in vitro and in vivo evaluate the effect of Rhatany roots extract (RRE) as an anti-eimerial and anti-apoptotic agent against murine eimeriosis induced by Eimeria papillata. Methods: Phytochemical screening by gas chromatography-mass spectrometry analysis (GC-MS) was used to detect active compounds in RRE. In vitro anti-eimerial activity of RRE (200, 100, 50 mg/ml), amprolium, phenol, Dettol™, and formalin were studied after incubation with non-sporulated Eimeria oocysts. For the in vivo study, twenty-five male C57BL/6 mice were randomly allocated into five groups. Animals in the first group were just given distilled H
2 O, while those in the second group were given 200 mg/kg RRE for 5 days. The Eimeria parasite’s oocysts were infected into the third, fourth, and fifth groups. For treatment, RRE (200 mg/kg) and amprolium (120 mg/kg) were orally given to the 4th and 5th groups for five days, respectively. All mice were euthanized, on day 5 post-infection, to collect the jejunal tissues under study. Investigations were undertaken into the oocyst output in feces and goblet cells in mice jejuna. Assays for glutathione peroxidase (GPx), hydrogen peroxide (H2 O2 ), and myeloperoxidase (MPO) were also performed. In jejunal tissue, cysteine aspartic acid protease-3 (Caspase-3) was counted using immunohistochemistry, while BCL2-associated X protein (Bax) and B-cell lymphoma-2 (BCL-2) were assayed using ELISA. In addition, mRNA expression of the goblet cell response gene (MUC2) was detected using real-time PCR. Results: Phytochemical screening by GC-MS demonstrated the presence of 22 compounds in the RRE. The in vitro study revealed that RRE significantly inhabited the oocyst sporulation in a dose-dependent manner. By day 5 after infection with the Eimeria parasite, the number of oocysts in mice feces was significantly reduced after RRE treatment (1.308 × 106 ± 1.36 × 105 oocysts/g feces) compared to the infected group (5.387 × 106 ± 4.29 × 105 oocysts/g feces). Moreover, the Eimeria infection reduced the number of goblet cells of mice jejuna and its specific gene, MUC2. The treatment with RRE increased the number of goblet cells/villus from 3.45 ± 0.17 to 6.04 ± 0.23, associated with upregulation for MUC2 from 0.26 to 2.39-fold. Also, the Eimeria experimental infection lowered the activity of the antioxidant enzyme represented by GPx (23.99 ± 3.68 mg/g tissue), while increasing the stress parameters of hydrogen peroxide (0.07 ± 0.01 mM/g) as well as the activity of MPO (66.30 ± 3.74 U/mg). The production of apoptotic markers including Caspase-3 (68.89 ± 2.67 U/g) and Bax (159.05 ± 6.50 pg/ml) was significantly elevated while decreasing the anti-apoptotic marker of BCL2 (0.42 ± 0.07 pg/ml). Our study proved that RRE significantly reduced oxidative stress, and apoptotic markers as well as the inflammatory activity of MPO. Also, antioxidant enzyme and anti-apoptotic activity in the jejunum of E. papillata-infected mice were enhanced after RRE treatment. Conclusion: Our study highlights the potential of RRE as a natural solution for coccidiosis management by modulating apoptosis in E. papillata host cells. However, further research is needed to fully understand the underlying mechanisms and enhance our understanding of its therapeutic efficacy. [ABSTRACT FROM AUTHOR]- Published
- 2024
- Full Text
- View/download PDF
17. Strong Consistency of Incomplete Functional Percentile Regression.
- Author
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Alamari, Mohammed B., Almulhim, Fatimah A., Litimein, Ouahiba, and Mechab, Boubaker
- Subjects
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QUANTILE regression , *MISSING data (Statistics) , *RANDOM variables , *REGRESSION analysis , *FOOD quality , *YOGURT - Abstract
This paper analyzes the co-fluctuation between a scalar response random variable and a curve regressor using quantile regression. We focus on the situation wherein the output variable is observed with random missing. For this incomplete functional data situation, we estimate the quantile regression by combining two principal nonparametric methods: the local linearity approach (LLA) and the kernel nearest neighbor (KNN) algorithm. We study the asymptotic properties of the constructed estimator by establishing, under general assumptions, uniform consistency over the number of neighborhoods. This asymptotic result provides good mathematical support for the selection of the optimal neighborhood. We examine the feasibility of the constructed estimator using artificially generated data. Moreover, we apply the quantile regression technique in food quality by predicting the riboflavin quantity in yogurt using spectrometry data. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
18. k -Nearest Neighbors Estimator for Functional Asymmetry Shortfall Regression.
- Author
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Alamari, Mohammed B., Almulhim, Fatimah A., Kaid, Zoulikha, and Laksaci, Ali
- Subjects
- *
VECTOR autoregression model , *FINANCIAL risk management , *FINANCIAL risk , *K-nearest neighbor classification , *CORPORATE finance - Abstract
This paper deals with the problem of financial risk management using a new expected shortfall regression. The latter is based on the expectile model for financial risk-threshold. Unlike the VaR model, the expectile threshold is constructed by an asymmetric least square loss function. We construct an estimator of this new model using the k-nearest neighbors (kNN) smoothing approach. The mathematical properties of the constructed estimator are stated through the establishment of the pointwise complete convergence. Additionally, we prove that the constructed estimator is uniformly consistent over the nearest neighbors (UCNN). Such asymptotic results constitute a good mathematical support of the proposed financial risk process. Thus, we examine the easy implantation of this process through an artificial and real data. Our empirical analysis confirms the superiority of the kNN-approach over the kernel method as well as the superiority of the expectile over the quantile in financial risk analysis. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
19. Non-Invasive Brain Sensing Technologies for Modulation of Neurological Disorders.
- Author
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Alfihed, Salman, Majrashi, Majed, Ansary, Muhammad, Alshamrani, Naif, Albrahim, Shahad H., Alsolami, Abdulrahman, Alamari, Hala A., Zaman, Adnan, Almutairi, Dhaifallah, Kurdi, Abdulaziz, Alzaydi, Mai M., Tabbakh, Thamer, and Al-Otaibi, Faisal
- Subjects
TRANSCRANIAL direct current stimulation ,TRANSCRANIAL magnetic stimulation ,BRAIN stimulation ,PARKINSON'S disease ,CLOSED loop systems - Abstract
The non-invasive brain sensing modulation technology field is experiencing rapid development, with new techniques constantly emerging. This study delves into the field of non-invasive brain neuromodulation, a safer and potentially effective approach for treating a spectrum of neurological and psychiatric disorders. Unlike traditional deep brain stimulation (DBS) surgery, non-invasive techniques employ ultrasound, electrical currents, and electromagnetic field stimulation to stimulate the brain from outside the skull, thereby eliminating surgery risks and enhancing patient comfort. This study explores the mechanisms of various modalities, including transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS), highlighting their potential to address chronic pain, anxiety, Parkinson's disease, and depression. We also probe into the concept of closed-loop neuromodulation, which personalizes stimulation based on real-time brain activity. While we acknowledge the limitations of current technologies, our study concludes by proposing future research avenues to advance this rapidly evolving field with its immense potential to revolutionize neurological and psychiatric care and lay the foundation for the continuing advancement of innovative non-invasive brain sensing technologies. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
20. Local linear estimation for the censored functional regression.
- Author
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Almulhim, Fatimah A., Merouan, Torkia, Alamari, Mohammed B., and Mechab, Boubaker
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ASYMPTOTIC normality ,ASYMPTOTIC distribution ,REGRESSION analysis ,INDEPENDENT variables ,KAPLAN-Meier estimator - Abstract
This work considers the Local Linear Estimation (LLE) of the conditional functional mean. This regression model is used when the independent variable is functional, and the dependent one is a censored scalar variable. Under standard postulates, we establish the asymptotic distribution of the LLE by proving its asymptotic normality. The obtained results show the superiority of the LLE approach over the functional local constant one. The feasibility of the studied model is demonstrated using artificial data. Finally, the usefulness of the obtained asymptotic distribution in incomplete functional data is highlighted through a real data application. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
21. Sternoclavicular Septic Arthritis and Surgical Intervention: A Case Report
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Alnasser, Abdullah, primary, Alamari, Zeyad S, additional, Almutairi, Taif M, additional, Aljohani, Hamid T, additional, and Almulla, Ahmed m, additional
- Published
- 2024
- Full Text
- View/download PDF
22. Effect of oral isotretinoin therapy on thyroid function in patients with moderate-to-severe acne vulgaris: A prospective study
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Fahad AlSaif, Hend AlOtaibi, Amal Balbisi, Ahmad AlAmari, Faisal AlSaif, AlBatool AlAmari, Abdulrhman AlDakhil, Arwa AlModayfer, and Nourah AlSyefi
- Subjects
acne vulgaris ,isotretinoin ,thyroid dysfunction ,Dermatology ,RL1-803 - Abstract
Introduction: Despite its growing use, the side effects of isotretinoin therapy are not fully understood. Studies have suggested that isotretinoin can cause thyroid dysfunction, suggesting the need to investigate thyroid dysfunction as a possible side effect of oral isotretinoin therapy. Purpose: The main objective of the study is to investigate the association between isotretinoin therapy and thyroid dysfunction. Methods: In all, 51 patients (male, 21; female, 30; aged 18–25 years) with moderate-to-severe acne vulgaris were treated with 0.5 mg/kg/day oral isotretinoin (cumulative dose: 120–150 mg/kg). Serum-free thyroxine (T4), thyroid-stimulating hormone (TSH), and thyroglobulin (TGA) and thyroid peroxidase (TPO) antibody levels were measured. Results: TSH levels at baseline and at the 2nd, 4th, 6th, and 8th months of treatment were 2.3307 ± 1.097, 2.5824 ± 1.34, 2.678 ± 1.133, 2.3 ± 1.17, and 2.7 ± 2.17 IU·mL, respectively, with no significant change from baseline (P = 0.526, P = 0.552, P = 0.530, and P = 0.910 at 2, 4, 6, and 8 months, respectively). Serum levels of free T4, TGA, and TPO antibodies were unchanged. Conclusions: Follow-up screening for thyroid dysfunction may not be necessary for patients receiving oral isotretinoin.
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- 2020
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23. Environment-Friendly Control Potential of Two Citrus Essential Oils against Aphis punicae and Aphis illinoisensis (Hemiptera: Aphididae)
- Author
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Saqer S. Alotaibi, Hadeer Darwish, Ahmed K. Alzahrani, Sarah Alharthi, Akram S. Alghamdi, Amal M. Al-Barty, Mona Helal, Amal Maghrabi, Alaa Baazeem, Hala A. Alamari, and Ahmed Noureldeen
- Subjects
Citrus aurantium ,Citrus reticulata ,essential oil ,Aphis punicae ,Aphis illinoisensis ,aphicidal activity ,Agriculture - Abstract
Aphids are serious pests of a wide range of agricultural crops, including pomegranates and grapevines. In addition, due to the negative environmental impacts of chemical insecticides, these pests are developing important resistance against aphicides. Therefore, one alternative method to control aphids is the use of essential oils (EO). The present study aimed to evaluate the insecticidal activity of Citrus aurantium and C. reticulata peel EO at different concentrations and with different exposure periods to pomegranate and grapevine aphids, Aphis punicae and A. illinoisensis via the topical application method under laboratory conditions. The results reveal that C. aurantium L. EO had greater toxicity against pomegranate and grapevine aphids, with LC50 of 0.37 and 0.82 μL/mL, respectively, at 48 h after application. The highest repellence effect was estimated for C. aurantium EO, at 2.5 μL/cm2, on A. punicae, with a value of 100% after an exposure time of 3 h, in contrast to the 88% repellence estimated for A. illinoisensis. The GC-MS investigation of both essential oils identified limonene, 3-carene, pinene, and p-cymene as active substances that could be attributed to the effects observed. Overall, our results offer a potential tool to control the two aphid species and could help in the development of integrated insect management in pomegranate and grapevine fields.
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- 2022
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24. Orthodontics and Temporomandibular Disorders: An Overview
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Aldayel, Abdullah M, primary, AlGahnem, Zainab J, additional, Alrashidi, Ibtehal S, additional, Nunu, Duaa Y, additional, Alzahrani, Afnan M, additional, Alburaidi, Wedad S, additional, Alanazi, Fahad, additional, Alamari, Abdulrahman S, additional, and Alotaibi, Rami M, additional
- Published
- 2023
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25. A Literature Review on Cochlear Implant Activation: From Weeks to Hours
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Alahmadi, Asma, primary, Abdelsamad, Yassin, additional, Alothman, Noura I., additional, Alshalan, Afrah, additional, Almuhawas, Fida, additional, AlAmari, Nouf A., additional, Alyousef, Mohammed Y., additional, Alhabib, Salman F., additional, and Hagr, Abdulrahman, additional
- Published
- 2023
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26. Endoscopic Reconstruction of Skull Base Defects Using Tutoplast
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Ghassan Alokby MD, Kholoud Mohammed AlAmari MD, Jamal Mohammed S. Abdullah MD, Mohammed Tayed Hazazi MD, and Fawaz Makki MD, MSc, FRCS(c)
- Subjects
Otorhinolaryngology ,RF1-547 ,Immunologic diseases. Allergy ,RC581-607 - Abstract
Background Various graft materials that are classified as autografts, xenografts, and allografts based on their origin have been used to endoscopically repair skull base defects. Tutoplast® (Tutogen Medical GmbH), an allogeneic natural collagen matrix, is processed through chemical sterilization that preserves tissue biocompatibility and structural integrity. Objective To study the safety and efficacy of Tutoplast Fascia Lata and Tutoplast Temporalis Fascia® as primary graft materials in the endoscopic reconstruction of skull base defects of different sizes and etiologies and to compare the outcomes with those of other traditional graft materials based on our experience. Methods This is a multi-center retrospective chart review of patients who underwent cerebrospinal fluid leak (CSF) endoscopic reconstruction with Tutoplast Fascia Lata or Tutoplast Temporalis Fascia as either a stand-alone reconstruction material or a part of a multilayer reconstruction depending on the defect at Prince Sultan Military Medical City and King Faisal Specialist Hospital and Research Center in Riyadh, Saudi Arabia, between 2017 and 2020. Our inclusion criteria were CSF leak repair with Tutoplast and a transnasal endoscopic approach. We reviewed demographic data, intraoperative and postoperative complications, repair materials, repair failure, defect size and location. Results Tutoplast® was used as the primary graft material in 33 cases. Our main outcome was repair success with lack of post operative CSF leak, observed in 30 cases (90.9%). There was no significant association between postoperative CSF leaks and factors including different defect sizes, defect sites, demographic data, hospitalization duration, or postoperative radiation in oncological cases. Conclusion Tutoplast alone or in combination with other materials can be used safely and effectively for skull base defects repair.
- Published
- 2021
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27. The Ideal Applicant to the Saudi Plastic Surgery Residency Program
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Qutaiba N. M. Shah Mardan, MBBS, Nouf A. Alamari, Hatan M. Alzahrani, MBBS, Mohammed A. Almarghoub, MBBS, Nouf A. Al Saud, MBBS, DES, DESC, and Moraya S. Alqahtani, MBBS, FRCSC
- Subjects
Surgery ,RD1-811 - Abstract
Background:. Securing a plastic surgery position is a demanding task for students. Although many papers have been published internationally discussing the traits and features deemed important from the point of view of plastic surgery program directors, a gap exists in the literature where this aspect is not covered in Saudi Arabia. The aim of this study was to fill this gap. Methods:. In this cross-sectional study, a survey was developed targeting all current and former Saudi plastic surgery training program directors. SPSS was used to calculate frequencies and present percentages; independent t-test was done to look for mean differences. Ethical approval was obtained from a local institution. Results:. All current and former Saudi plastic surgery program directors participated (n = 17), including the 8 (47.1%) current directors. When asked to rank 7 items on a scale of importance, they scored a mean of 6.2, 5.8, 5.4, 4.88, 4.82, 4.6, and 3.7 for good impression on interviews, prior experience, research experience, the grade point average (GPA), oral or poster presentations on events, the Saudi Medical Licensing Examination (SMLE), and attaining a post-graduate degree, respectively. The majority [n = 7 (41%)] considers the mode of communication, such as phone calls, as the most important aspect in recommendations. They prefer candidates who took electives/rotations at their department [n = 12 (71%)] and give more value to high-quality publications [n = 9 (47%)]. Applicant’s gender was not important. Conclusion:. With early planning, this article could serve as a guide for medical students interested in plastic surgery to build their assets toward a successful interview.
- Published
- 2021
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28. IMIGRAN DAN MASALAH INTEGRASI SOSIAL
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Muhammad Fauzan Alamari
- Subjects
immigrant ,economic ,social integration ,Social Sciences ,International relations ,JZ2-6530 - Abstract
Imigrasi telah menjadi bagian dari sejarah manusia, bahkan hingga sebelum masehi.Kondisi imigran saat ini menjadikan banyak negara mengalami dilemma yang sangat besar dalam hal penanganan dan pengintegrasian imigran.Hal ini tidak mudah bagi para imigran dikarenakan adanya pro dan kontra oleh masyarakat di negara penerima mengenai kehadiran imigran, yang menyadikan masalah ini semakin rumit.Seperti yang terjadi di Amerika Serikat, Australia, Beberapa negara Eropa dan juga Indonesia. Tetapi pada kenyataan imigran seringkali memberikan kontribusi yang luar biasa dibidang ekonomi, budaya, tetapi disaat yang sama juga imigran sering kali menimbulkan masalah yang besar.
- Published
- 2020
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29. Safe Travel Practices and Awareness among Diabetic Patients
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Afnan S. Younis, Noura A. Abouammoh, Layla M. AlBreacan, Yara Aldigi, Atikah Kadi, Nora Almohideb, Nouf AlAmari, and Turky H. Almigbal
- Subjects
Article Subject ,Health, Toxicology and Mutagenesis ,Public Health, Environmental and Occupational Health - Abstract
Objective. To measure the knowledge of Saudi patients with diabetes in coping with their condition and to assess their practice of disease control during travels. Study Design. Cross-sectional study using a self-administered questionnaire. Method. This study was conducted between September 2018 and May 2019 at a University hospital in Riyadh, Saudi Arabia. The questions were adopted from guidelines and advices provided by the CDC, American Diabetic Association, and other references. Bivariate and multivariate analyses were used to identify factors associated with diabetic control during travels. Results. From the included 242 patients, 33.6% showed the good practice of diabetic control during travels. 23.7% of patients were communicated by their doctors about the importance of consultations before traveling and 20.7% encountered complications during travels. Factors associated with doctors’ consultation before travel are patients’ concerns about travel duration and possible risks during trip. (OR = 2.588, 95% CI = 5.308–1.261), (OR = 3.525, 95% CI = 8.152–1.525); respectively. Conclusion. Patient awareness and education about the importance of proper diabetic self-monitoring and control during travels is crucial as the study showed suboptimal diabetes management practice. Practice Implications. Physicians should proactively educate patients about the importance of seeking advice before their travels.
- Published
- 2023
30. Catalyst behind Sri Lanka Downfall
- Author
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Muhammad Fauzan Alamari
- Subjects
Ecology ,Insect Science ,Ecology, Evolution, Behavior and Systematics - Abstract
Sri Lanka shocked the world with a downfall due to an economic crisis. Among the states that had to mitigate the pandemic, Sri Lanka appears to struggle with the situation and as a result of this event, Sri Lanka is in a position of overdue debt with a total of 51 billion USD worth of debt. The inflation was created by economic shortage activity with imbalanced trade records leads to the overthrown of Sri Lanka’s president and as the result produced a vacuum of power. This paper will use of dependency theory to describe the cause of Sri Lanka’s collapse by examining several factors such as civil war, pandemic, oil price rise, and recent terrorist attack.
- Published
- 2022
31. Effects of Rhazya Stricta plant organic extracts on human induced pluripotent stem cells derived neural stem cells
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Alawad, Abdullah Othman, primary, Alagrafi, Faisal Sultan, additional, Alfahad, Ahmed Jaman, additional, Alamari, Hala Abdulrahman, additional, Alghamdi, Fatimah Othman, additional, Fallatah, Hussam Mokhtar, additional, Aodah, Alhassan Hamood, additional, Alyousef, Sultan Suleiman, additional, Bakhrebah, Muhammed Adnan, additional, Alanazi, Ibrahim Oqla, additional, and Fallatah, Mohannad Mokhtar, additional
- Published
- 2023
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32. UPAYA MANUVER ISRAEL DI AMERIKA LATIN
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Muhammad Fauzan Alamari
- Subjects
General Medicine - Abstract
Israel positions in the development of world met a position where Israel is hardly to make a move, fact that Israel’s economy is very strong in the Middle East region made it hard for Israel to export and distribute their porduk. At the same time, Israel need receognition from other states so Israel could get legitimation in Intenational stage. Latin America has been chososen by Israel with a special goal because there is no major sentiment by majority religion about how Israel’s born process. Despite comparing to Asia’s with their religion and history. Therefore, one question showed up on how’s Israel effort on gaining support from Latin Americas’ states? This research using qualitative method by using literature review, documentation, observation and focus group discussion as data gathering technique method. By using two level games as theory so it could create a helicopter view covering all sides and aspects of Israel maneuvers in Latin America.
- Published
- 2022
33. STRATEGI PENINGKATAN WISATAWAN ASING DI KOTA CIMAHI PADA TAHUN 2023
- Author
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Muhammad Fauzan Alamari and Tholhah Tholhah
- Abstract
Pariwisata merupakan sektor penting bagi suatu wilayah, dalam hal ini pariwisata akan memberikan dampak positif dalam pertumbuhan ekonomi terutama bagi mereka yang berhubungan langsung dengan kegiatan pariwisata seperti restoran dan penyedia penginapan. Cimahi menjadi salah satu daerah yang memiliki potensi besar dalam sektor pariwisata melalui ciri khas dan sumber daya yang dimilikinya, ciri khas tersebut adalah Cimahi yang dikenal sebagai Kota Militer (Kota Hijau) dikarenakan terdapat sejarah, bangunan, dan fasilitas kemiliteran yang cukup lengkap. Penelitian ini menggunakan tipe pendekatan deskriptif analisis, data-data yang digunakan berasal dari teknik pengumpulan berupa wawancara, observasi, dan dokumentasi. Pemerintah Kota Cimahi memiliki beberapa strategi untuk memanfaatkan sumber daya yang dimiliki Kota Cimahi agar dapat memajukan sektor pariwisata, beberapa upaya tersebut adalah dengan mulai membentuk kerja sama dalam konsep sister city, meluncurkan program Cimahi Military Heritage Tourism dengan Sekoci (Serba Kota Cimahi) sebagai transportasi utama, program Cimahi City Tour, serta melakukan koordinasi dengan pengelola daerah-daerah wisata. Kesimpulannya program-program tersebut harus dilaksanakan dengan baik melalui koordinasi dengan berbagai pihak, contohnya dengan kementerian dan dinas-dinas terkait serta lembaga swadaya masyarakat.
- Published
- 2022
34. Medication use 3-6 months after acute covid-19 and fatigue
- Author
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Alamari, Kowsar, Mantel-Teeuwisse, A.K. (Thesis Advisor), Alamari, Kowsar, and Mantel-Teeuwisse, A.K. (Thesis Advisor)
- Published
- 2023
35. Safe Travel Practices and Awareness among Diabetic Patients
- Author
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Younis, Afnan S., primary, Abouammoh, Noura A., additional, AlBreacan, Layla M., additional, Aldigi, Yara, additional, Kadi, Atikah, additional, Almohideb, Nora, additional, AlAmari, Nouf, additional, and Almigbal, Turky H., additional
- Published
- 2023
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36. Catalyst behind Sri Lanka Downfall
- Author
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Alamari, Muhammad Fauzan, primary
- Published
- 2022
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37. An unusual case of gastric angiolipoma presenting with upper gastrointestinal bleeding
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Alghamdi, Saeed Abdulrahman, primary, Alshammery, Sahar Matter, additional, Alamari, Mahammad Saeed, additional, Alshehri, Mohammed Ali, additional, and Alshahrani, Amer Saeed, additional
- Published
- 2022
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38. Prevalence of Tension-Type Headache among Medical Students in Tabuk University, Saudi Arabia
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Yousef Hussain J. Alharthi, Amal Mohammad H. Albalawi, AlTurki Abdulrahman Mohammed, Manar Abubaker A. Bawadood, Rayyan Fahad H. Altemani, Nahaa Eid B. Alsubaie, Asawir Mohammed Al Qurashi, Saud Abdulrahman Saad Alghamdi, Abdulaziz A. Altawili, Maram Yehia M. Alzahrani, Mohammed Abdulhafith R. Alotaibi, Hyder Osman Mirghani, Aisha Abdullah Alamari, Mohammed Aboubaker R. Alshafey, and Ahmed Marwan A. Alamrani
- Subjects
medicine.medical_specialty ,business.industry ,Tension (geology) ,Family medicine ,education ,Medicine ,business - Abstract
Background: Headaches disorders have a significant burden on the world. Tension Type Headache is the most common type among primary headaches. Since medical students are exposed to a lot of stress, and it is associated with a tension-type headache, the importance of this study comes. This study aims to measure the prevalence of tension-type headache among medical students at Tabuk University 2020. Methodology: A cross-sectional study in Tabuk, Saudi Arabia was conducted. The study included medical students at the University of Tabuk in the academic years from 2nd to 6th grades during the calendar year of 2020. An adapted semi-structured self-administered questionnaire was retrieved from other validated questionnaires. The internal validity and reliability of the questionnaire were tested using Cronbach's alpha test and was highly reliable (25 items, α = .715). Both medical and research experts assessed the face and content validity. The data were coded, tabulated, and analyzed using the Statistical Package for the Social Sciences (SPSS, version 27). Results: The total number of the students was 380 (response rate, 78.6%). 55.22% were females, and 44.78% were males their mean age was 21.18 ± SD 1.78 years. Out of the 297 students, only 122 met the diagnostic criteria. The 1-year prevalence Tension Type Headache (TTH) included the three types: frequent TTH 67.2%, 18.0% infrequent TTH, and only 14.8% suffered from chronic TTH. The most common aggravating factors included studying stressors (82%), 68% of the participants reported daily activity interference, and 48.4% reported that headache aggravate with routine physical activities (e.g., walking or climbing stairs). The headache quality varied between throbbing/pulsating (54.9%), pressing/tightening (68.9%) and sharp/stabbing (10.7%). The median headache intensity was 5.25 at pain level score (IQR =2). Only 28% of the students sought counseling where the main analgesic used was Acetaminophen (74%). Many non-pharmacological therapies were practiced by the students to relieve headache, including sleep (60.7%), rest (63.1%) and caffeine (41.8%).23% of the medical students reported that they sought medical counseling to maintain their performance level. There was a statistically significant difference between the average age of medical students suffering from frequent and infrequent TTH, t(102) = 2.31, p = .023. Conclusion: Tension-type headache is a prevalent type of headache among Saudi medical students. Prevalence and aggravating factors in our study were comparable to previously reported literature. Future studies with large sample size may be required among all university students to define burden of the case in Saudi Arabia.
- Published
- 2021
39. AWARENESS OF DIABETICS ABOUT THE NEED TO ADHERE TO AND CONTROL TREATMENT
- Author
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Dr. Lubna Abdulrahman Hafiz, Dr. khadija Abdulrahman Basaikh, Dr. Azhar Abdulrahman Kurban, Dr. Elaf abdulkader kanoori, Dr. Majdolen Magdi Hassanin, Dr. Faris Adnan Baawad, Dr. Turki Saleh Anwar, Dr. Hanoof Mohammed Alqahtani, Dr. Amal ghazi alattas, Dr. Aljohara Saad Alsuhaili, Dr. Mohammad Ali Alamari, Dr.Abdarahman Saud Alanazi, Dr.Mahmood ali hasan, Dr.Ayoob jaafar ayoob, Dr. Safiah Abdulkarim Alasif
- Abstract
Background: Diabetes management depends on education, awareness, and practice. The primary aim of the current study is to investigate awareness and medication non-adherence by Type 2 diabetes mellitus patients. Methods: The cross sectional study was carried out for a period of 12 months, this is because cross-sectional studies have a specific beginning and ending time. A specific population sample of about 125 patients would be used. Thus, the independent variables include aspects like age, gender, type or nature of diabetics, complexity of drug regiments among other variables. The dependent variable was adherence to medication. The cross-sectional approach allowed the researcher to analyze the different variables that lead to lack of adherence to medication among diabetic patients. The main of undertaking this cross-sectional study would be to describe and assess the characteristics of diabetic patients who do not adhere to medication. Results: The study included 453 type 2 diabetic patients after exclusion of non-diabetic participants. Most of study participants were informed with diabetes since more than one year (n= 364, 80.4%). However, participants started using medications after a while of diagnosis. Most of them started since one year (n= 288, 63.6%). About two thirds of participants use 1-2 medications (n= 298, 65.8%). The vast majority of study participants have good adherence to diabetic medications. Participants with longer duration with the disease had better adherence (P< 0.001). Furthermore, participants with low number of medication had better adherence (P= 0.035). Conclusion: On average, patients lacked diabetes management knowledge. Insulin-treated or long-term diabetic patients are at a greater risk for problems, although they have self-help techniques. Improved treatment of diabetes and its complications may arise from interventions that increase people's awareness of the condition, how often they check their blood sugar, how consistently they take their prescriptions, and how much they value physical exercise. Our results also show that people with diabetes, especially insulin-dependent or long-term sufferers, should attend diabetes education/awareness programs and participate in healthy lifestyle and self-help regimens immediately following diagnosis.
- Published
- 2022
- Full Text
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40. Does Adenoid Hypertrophy Increase the Risk of Orbital Complication in Children with Acute Sinusitis?
- Author
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Ayshah Almahboob, Ahmed Alhussien, Kholoud AlAmari, Adeena Khan, Yasser AlFaky, and Saad Alsaleh
- Subjects
Otorhinolaryngology ,Surgery - Published
- 2022
41. An unusual case of gastric angiolipoma presenting with upper gastrointestinal bleeding
- Author
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Saeed Abdulrahman Alghamdi, Sahar Matter Alshammery, Mahammad Saeed Alamari, Mohammed Ali Alshehri, and Amer Saeed Alshahrani
- Subjects
Infectious Diseases ,Case Report ,Parasitology ,Microbiology - Abstract
Gastric angiolipomas (GA) are rare benign tumors that can present with gastrointestinal bleeding and anemia. We describe a 73-year-old woman who presented with a 3-day history of fatiguability, epigastric pain and melena. A computed tomography scan revealed a hypodense lesion, measuring 6 × 6 × 5 cm, along the upper part of the stomach. An upper endoscopy revealed a large polypoid lesion, measuring 8 × 6 cm, between the cardia and body of the stomach. Multiple biopsy specimens were taken, and a histopathological examination showed an acute erosive helicobacter-associated reactive gastritis but no definitive atypia. A linear endoscopic ultrasound revealed a large, homogenous, hyperechoic lesion, consistent with a lipoma, in the body of the stomach. A fine needle aspiration was negative for malignancy. A laparoscopy was offered, and a wedge resection was performed. A histopathological examination revealed a well-circumscribed, encapsulated lipomatous tumor in the gastric submucosa with focal mucosal ulceration. The patient had an uneventful postoperative recovery and her hemoglobin level subsequently returned to normal. Overall, clinicians may be unfamiliar with GA because patients may present with signs and symptoms that can be confused with other gastrointestinal conditions. Physicians should be aware of the characteristic histopathological features to distinguish GA from other diseases of the gastrointestinal tract that may share similar clinical or radiologic features.
- Published
- 2022
42. How Accurate are Patient Histories? Hepatitis B Knowledge and Prevalence among Dental Patients
- Author
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Mohamad Almech, Madeha Sadki, Hala Alras, Baydaa Koussa, Jumana Yaseen, Sulaiman Alamari, Mohamed Yaser Kharma, and Ahmed Aldwaik
- Subjects
Pediatrics ,medicine.medical_specialty ,business.industry ,medicine ,General Earth and Planetary Sciences ,Hepatitis B ,medicine.disease ,business ,General Environmental Science ,Dental patients - Published
- 2021
43. The Role of SGLT-2 Inhibitors as an Adjuvant to Insulin Therapy in Type-1 Diabetes Mellitus- Literature Review
- Author
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Aalaa Mohammad Algarni, Sultan Ali Alshehri, Sultan Abdulwahab M. Asiri, and Manal Mohammed Alamari
- Subjects
Type 1 diabetes ,business.industry ,medicine.medical_treatment ,Insulin ,Hypoglycemia ,medicine.disease ,Bioinformatics ,Insulin resistance ,Diabetes mellitus ,medicine ,Risk factor ,business ,Adjuvant ,Glycemic - Abstract
Background: Type 1 diabetes mellitus is the main risk factor for cardiovascular complications. Therefore, intensified insulin therapy might be needed to achieve better glycemic control in some patients. However, insulin therapy might lead to increase body weight and induce hypoglycemia. Increase body weight is directly correlated to insulin resistance, the main factor for cardiovascular risk. Objective: To assess the effectiveness of adding SGLT2 inhibitors to insulin therapy in type 1 diabetes mellitus. Methods: We searched in the PubMed database looking for relevant articles on the topic. We used Mesh words search, including SGLT2 inhibitor, sotagliflozin, type 1 diabetes mellitus, insulin treatment. Conclusion: Adding oral antidiabetic agents, such as SGLT2 or dual SGLT inhibitors to insulin regimen might be beneficial in improving insulin resistance. Thus, it achieved better insulin resistance by decrease daily insulin requirements and bodyweight control, leading to better cardiovascular outcomes among Type-1 diabetes patients.
- Published
- 2021
44. Atrophic Rhinitis Secondary to an Infection of Unusual Bacteria: A Case Report and Literature Review
- Author
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Alyousef, Mohammed, primary, Alroqi, Ahmad, additional, and AlAmari, Nouf, additional
- Published
- 2022
- Full Text
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45. Environment-Friendly Control Potential of Two Citrus Essential Oils against Aphis punicae and Aphis illinoisensis (Hemiptera: Aphididae)
- Author
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Alotaibi, Saqer S., primary, Darwish, Hadeer, additional, Alzahrani, Ahmed K., additional, Alharthi, Sarah, additional, Alghamdi, Akram S., additional, Al-Barty, Amal M., additional, Helal, Mona, additional, Maghrabi, Amal, additional, Baazeem, Alaa, additional, Alamari, Hala A., additional, and Noureldeen, Ahmed, additional
- Published
- 2022
- Full Text
- View/download PDF
46. Potential significance of medicinal plants in forensic analysis: A review
- Author
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Eman Khan, Hala Alamari, Sarah Albogami, Areej Hamed AL-Shanbari, Doaa Alshoaibi, Hanan M. Alghamdi, Wafa Almalki, Saqer S. Alotaibi, Bashaer Alshanqiti, and Hadeer Darwish
- Subjects
0106 biological sciences ,0301 basic medicine ,QH301-705.5 ,Human life ,Poisonous ,Context (language use) ,Review ,01 natural sciences ,03 medical and health sciences ,Medicinal plants ,Forensic diagnostic ,High doses ,Crime scene ,Biology (General) ,business.industry ,food and beverages ,Biotechnology ,Forensic science ,030104 developmental biology ,Poisonous effects ,General Agricultural and Biological Sciences ,business ,Psychology ,010606 plant biology & botany - Abstract
Medicinal plants are a two-edged sword that might be exploited as a treatment specific dosage, and as deadly poisonous substances to commit murder or suicide when administered in high doses. Forensic experts can collect traces and residual materials from these toxic medicinal plants at a crime scene as forensic evidence. Further, more investigations need to be deeply implemented to in the future to understand the significance of medicinal plants in forensic investigations to detect these criminal offenses. Additionally, to provides a deep understanding of chemical substances that can impact human life positively or negatively with different doses as well as identifying the optimal or overdose concentrations for either treatments or poisonous effects using recent biotechnological approaches. This review aims to illustrate different contributions and the significance of medicinal plants in the field and further employment in the context of forensic science, especially in the Kingdom of Saudi Arabia.
- Published
- 2021
47. Does Adenoid Hypertrophy Increase the Risk of Orbital Complication in Children with Acute Sinusitis?
- Author
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Almahboob, Ayshah, Alhussien, Ahmed, AlAmari, Kholoud, Khan, Adeena, AlFaky, Yasser, and Alsaleh, Saad
- Subjects
ADENOIDS ,HYPERTROPHY ,CHILD patients ,MUCOCILIARY system ,SINUSITIS ,OSTEOCHONDROSIS ,COMPUTED tomography - Abstract
Adenoid hypertrophy (AH) plays a role as a reservoir for bacterial growth and decreases mucociliary clearance which might contribute to the development of an infection. To compare the presence of AH in the pediatric population presenting with orbital complications as a result of ABRS and the control group radiologically. Patients who were diagnosed with OC as a result of ABRS labeled as case group, and the patients who had undergone computed tomography (CT) for indications other than sinonasal diseases were assigned as control group. Both groups were retrospectively reviewed to measure the adenoid, nasopharynx, and adenoid/nasopharynx ratio (ANR) in the axial and mid-sagittal planes. We compared 52 patients from case group to 57 control group. In the CT axial plane, adenoid length was greater in the OC group compared to the control group, with a significant difference (p-value = 0.02) of 14.2 ± 3.5 mm compared to 11.2 ± 7 mm, respectively. The ANRs were 2.9 in the OC group and 2.8 in the control group, with a p-value of 0.089. In the mid-sagittal plane, only the anteroposterior length was significantly greater in the OC group, with a mean of 19.9 ± 5.3 mm compared to 15.2 ± 8.8 mm in the control group (p-value = 0.007). The process of inflammation increased the anteroposterior length of the adenoids. However, the ANR was similar between the two groups, indicating that adenoid hypertrophy is not directly related as a risk factor for OC in pediatric patients with ARBS. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
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48. PREVENTION OF NOSOCOMIAL INFECTION AMONG PRIMARY HEALTHCARE PROFESSIONAL
- Author
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Dr. Naif mohsen Alwadai, Dr.Homood Mohammed Alsayegh, Qasem Mohammed Alamari, Saad Ali Alsulami, Azza Abdullah Ashi, Sultan Basir Ashi, Ibtihaj Yahya Ayash, Jamilh Hmza Takroni, Jameelah Mohammad Khayat, Sara Rishood Alhazmi
- Abstract
Hand hygiene decontamination remains one of the most significant and effective approaches for minimizing healthcare-associated illnesses and patient cross-infection. Florence Nightingale recommended that nurses wash their hands regularly throughout the day in 1860, exhibiting an early recognition of the effectiveness of this simple routine. We scan electronic databases such as PubMed and Embase for all relevant papers published up to 2022 on our topics. Nosocomial infection control procedures should be improved further among healthcare personnel and inpatients in designated healthcare settings that house suspected cases of emerging or undiscovered infectious diseases.
- Published
- 2022
- Full Text
- View/download PDF
49. A Proposed Design for Cross Platform Applications using Web Technologies
- Author
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C. Edward Chow and Jebreel Alamari
- Published
- 2021
50. Register of the Qurʾānic Narratives
- Author
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Zaid Alamari
- Subjects
Register (sociolinguistics) ,Mode (music) ,History ,Field (Bourdieu) ,Context (language use) ,Narrative ,Pericope ,Construct (philosophy) ,Monotheism ,Linguistics - Abstract
A text is an instance of a particular ‘register’, Halliday states. Because text carries indications of its context, it is possible, then, to reconstruct out of it (text) certain features of the situation in which it is produced. Accordingly, the register, being a configuration of semantic features typically associated with the contextual variables of field, tenor and mode, can be established. The aim of this study is to construct the context of situation of a short text (an instance of language) of the Qurʾānic story of Abraham in Q19 (41-50). This pericope represents but a sample of Abraham story told in different sūras of the Qurʾān; and as instance of language (text) in a context of situation, this story belongs to a register of narratives on prophetic stories which subject matter revolves about ‘monotheism’ as propagated by the Qurʾān. This study reports preliminary observations on some features of the Qurʾānic narratives register.
- Published
- 2020
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