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The aim was to examine the impact of pulmonary metastasectomy in patients with recurrent gynecologic cancers. Thirty-seven patients with isolated lung metastases (< 3 nodules) in recurrent epithelial gynecologic cancers were treated at Nagoya University Hospital between 1985 and 2013. The clinicopathological data for the 23 patients who underwent surgical resection were retrospectively analyzed, and their survival was compared with patients who received chemotherapy only. The median age at the time of surgery was 56 years (range 28–77). The studied population comprised 7 patients with 2 or 3 nodules and 8 patients with chemoresistant tumors, including fourteen cervical, 4 endometrial, and 5 ovarian primary tumors, with 5-year overall survivals (OSs) after surgery of 61, 100, and 100%, respectively. The survival of recurrence-free interval after initial treatment (>2 years) was significantly favorable (5-year OS 100% vs. 41.7%, p=0.006). Among the 6 patients with re-recurrence of lung metastases, 5 patients underwent a second pulmonary metastasectomy, and all of the patients are currently alive without disease. None of the 29 operations yielded severe complications. Although the survival rate showed a tendency to be higher in the surgery group than in the chemotherapy-only group, no significant difference was observed (5-year OS 81.7% vs. 49.5%, p=0.072). Our results indicate that pulmonary metastasectomy contributed to long-term survival with a low-risk of complications. Surgery to remove isolated lung metastases might provide a favorable prognosis for patients with long recurrence-free intervals and for patients with chemoresistant or re-recurrent tumors.

主論文雑誌掲載情報: Nagoya Journal of Medical Science. v.77, n.3, 2015, p.363-372

第4回スペースデブリワークショップ(2010年12月16-17日, 宇宙航空研究開発機構調布航空宇宙センター), 4th Space Debris Workshop(December 16-17, 2010, Chofu Aerospace Center, Japan Aerospace Exploration Agency (JAXA)), 昨今のスペースデブリ(デブリ)増加に伴い､衛星運用においてデブリとの衝突の可能性を無視できない状況になってきている。, このような状況をふまえ､JAXA統合追跡ネットワーク技術部(JAXA追跡)では､運用中の人工衛星におけるデブリの衝突を回避する運用の検討を進めてきた。2011年1月に打上予定である宇宙ステーンヨン補給機2号機(HTV2)の運用においても､打上からISSにキャプチャされるまでのランデブフェーズと､ISS離脱後から大気圏に再突入するまでのフェーズにおいて､デブリとの接近解析を実施する予定であり､デブリの軌道情報として､米国Space Trackが公開している軌道要素(TLE)を使用する。, 本講演では､HTV2軌道高度を通過するデブリ､すなわちHTV2に接近する可能性のあるデブリのTLEについて､軌道･大きさ別に軌道伝播音誤差を調べることで､統計的な傾向を把握した解析結果について述べる。, 形態: カラー図版あり, Physical characteristics: Original contains color illustrations, 資料番号: AA0064966011, レポート番号: JAXA-SP-10-011