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3. Partnership Between a Federal Agency and 4 Tribal Nations to Improve COVID-19 Response Capacities

Author

Kaur, Harpriya, Welch, Seh, Bhairavabhotla, Ravikiran, Weidle, Paul J., Santibanez, Scott, Haberling, Dana L., Smith, Eva M., Ferris-George, Wendy, Hayashi, Konrad, Hostler, Allie, Ao, Trong, Dieke, Ada, Boyer, Devon, King, Eric, Teton, Randy’L, Williams-Singleton, Nickie, Flying, Eva M., Hladik, Wolfgang, Marshall, Khiya J., Pourier, Delores, Ruiz, Zuleyma, Yatabe, Graydon, Abe, Karon, Parise, Monica, Anderson, Mark, Evans, Mary E., Hunt, Holly, and Balajee, S. Arunmozhi

Published
2022

4. Characteristics, complications, and sites of bleeding among infants and toddlers less than 2 years of age with VWD

Author

Dupervil, Brandi, Network, for the US Hemophilia Treatment Center, Abe, Karon, O’Brien, Sarah H, Oakley, Meredith, Kulkarni, Roshni, Thornburg, Courtney D, Byams, Vanessa R, and Soucie, J Michael

Subjects
Clinical Research, Rare Diseases, Pediatric, Hematology, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Aged, Child, Preschool, Cohort Studies, Hemorrhage, Humans, Infant, Infant, Newborn, Male, Plasma, von Willebrand Diseases, von Willebrand Factor
Abstract

Data on infants and toddlers (ITs) with von Willebrand disease (VWD) are lacking. We used data collected in the US Hemophilia Treatment Center Network (USHTCN) to describe birth characteristics, bleeding episodes, and complications experienced by 105 patients with VWD who were

Published
2021

11. The potential use of artificial intelligence for venous thromboembolism prophylaxis and management: clinician and healthcare informatician perspectives

Author

Lam, Barbara D., primary, Dodge, Laura E., additional, Zerbey, Sabrina, additional, Robertson, William, additional, Rosovsky, Rachel P., additional, Lake, Leslie, additional, Datta, Siddhant, additional, Elavakanar, Pavania, additional, Adamski, Alys, additional, Reyes, Nimia, additional, Abe, Karon, additional, Vlachos, Ioannis S., additional, Zwicker, Jeffrey I., additional, and Patell, Rushad, additional

Published
2024
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12. An Epidemiological Study Comparing Cancer- and Non-Cancer-Associated Venous Thromboembolism in A Racially Diverse Southeastern United States County

Author

Peseski, Andrew M., primary, Kapoor, Sargam, additional, Kuchibhatla, Maragatha, additional, Adamski, Alys, additional, Abe, Karon, additional, Beckman, Michele G., additional, Reyes, Nimia L., additional, Richardson, Lisa C., additional, Saber, Ibrahim, additional, Schulteis, Ryan, additional, Singh, Bhavana Pendurthi, additional, Sitlinger, Andrea, additional, Thames, Elizabeth H., additional, and Ortel, Thomas L., additional

Published
2024
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14. Attitudes towards venous thromboembolism prophylaxis including the use of artificial intelligence

Author

Lam, Barbara D., primary, Zerbey, Sabrina, additional, Pinson, Amanda, additional, Robertson, William, additional, Rosovsky, Rachel P., additional, Lake, Leslie, additional, Dodge, Laura E., additional, Adamski, Alys, additional, Reyes, Nimia, additional, Abe, Karon, additional, Vlachos, Ioannis S., additional, Zwicker, Jeffrey I., additional, Schonberg, Mara, additional, and Patell, Rushad, additional

Published
2023
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15. Vital Signs: Use of Recommended Health Care Measures to Prevent Selected Complications of Sickle Cell Anemia in Children and Adolescents--Selected U.S. States, 2019

Author

Schieve, Laura A., Simmons, Gretchen M., Payne, Amanda B., Abe, Karon, Hsu, Lewis L., Hulihan, Mary, Pope, Shammara, Rhie, Sarah, Dupervil, Brandi, and Hooper, W. Craig

Subjects
United States. National Heart, Lung and Blood Institute -- Analysis, Analysis, Complications and side effects, Genetic aspects, Health care industry, Medicaid -- Analysis, Health care industry -- Analysis, African Americans -- Analysis, Child health -- Analysis, Patient compliance -- Analysis, Hydroxyurea -- Complications and side effects, Medical care utilization -- Analysis, Medical care quality -- Analysis, Sickle cell anemia -- Complications and side effects -- Genetic aspects, Medical care -- Utilization -- Quality management, Children -- Health aspects
Abstract

Introduction Sickle cell disease (SCD), a group of inherited blood disorders characterized by abnormal hemoglobin, reduces life expectancy by >20 years (1). SCD primarily affects persons whose ancestors came from [...]

Published
2022

16. Venous thromboembolism prophylaxis for hospitalized adult patients: A survey of U.S. healthcare providers on attitudes and practices

Author

Lam, Barbara D., primary, Dodge, Laura E., additional, Datta, Siddhant, additional, Rosovsky, Rachel P., additional, Robertson, William, additional, Lake, Leslie, additional, Reyes, Nimia, additional, Adamski, Alys, additional, Abe, Karon, additional, Panoff, Samuel, additional, Pinson, Amanda, additional, Elavalakanar, Pavania, additional, Vlachos, Ioannis S., additional, Zwicker, Jeffrey I., additional, and Patell, Rushad, additional

Published
2023
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17. HTRS2023.P4.12 Perceptions on the potential for artificial intelligence to improve venous thromboembolism prevention

Author

Lam, Barbara D., primary, Dodge, Laura, additional, Datta, Siddhant, additional, Rosovsky, Rachel P., additional, Robertson, William, additional, Lake, Leslie, additional, Adamski, Alys, additional, Reyes, Nimia, additional, Abe, Karon, additional, Panoff, Samuel, additional, Pinson, Amanda, additional, Elavalakanar, Pavania, additional, Vlachos, Ioannis, additional, Zwicker, Jeffrey, additional, and Patell, Rushad, additional

Published
2023
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19. Survey of U.S. Healthcare Providers to Assess Attitudes and Practices Regarding Thromboprophylaxis of Hospitalized Adult Patients

Author

Lam, Barbara, primary, Dodge, Laura E., additional, Datta, Siddhant, additional, Rosovsky, Rachel P., additional, Robertson, William, additional, Lake, Leslie, additional, Reyes, Nimia, additional, Adamski, Alys, additional, Abe, Karon, additional, Panoff, Samuel, additional, Pinson, Amanda, additional, Elavalakanar, Pavania, additional, Zwicker, Jeffrey I., additional, and Patell, Rushad, additional

Published
2022
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23. sj-docx-1-phr-10.1177_00333549211063518 ��� Supplemental material for COVID-19 and Sickle Cell Disease���Related Deaths Reported in the United States

Author

Payne, Amanda B., Schieve, Laura A., Abe, Karon, Hulihan, Mary, Hooper, W. Craig, and Hsu, Lewis L.

Subjects
111799 Public Health and Health Services not elsewhere classified, FOS: Health sciences
Abstract

Supplemental material, sj-docx-1-phr-10.1177_00333549211063518 for COVID-19 and Sickle Cell Disease���Related Deaths Reported in the United States by Amanda B. Payne, Laura A. Schieve, Karon Abe, Mary Hulihan, W. Craig Hooper and Lewis L. Hsu in Public Health Reports

Published
2022
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24. Characteristics of Black and White suicide decedents in Fulton County, Geogia, 1988-2002

Author

Abe, Karon, Mertz, Kristen J., Powell, Kenneth E., and Hanzlick, Randy L.

Subjects
Suicide -- Risk factors, Suicide -- Research, Suicide -- Demographic aspects, Suicide -- Prevention, Government, Health care industry
Abstract

Objectives. We compared the prevalence of risk factors for Black and White suicide decedents in Fulton County, Georgia, from 1988-2002. Methods. We used data from the Fulton County Medical Examiner's Office to compile information on suicides that occurred in Fulton County between 1988 and 2002. We used the [X.sup.2] test and logistic regression to identify associations between suicide risk factors and race. Results. Black suicide decedents were more likely than White suicide decedents to be male (odds ratio [OR] = 2.06; 95% confidence interval [Cl] = 1.38, 3.09), to be younger, ([less than or equal to]24 y [OR=4.74; 95% (31=2.88, 7.81]; 25-34 y [OR=2.79; 95% Cl=1.74, 4.47]; 35-44 y [OR= 1.86; 95% Cl=1.13, 3.07]), and to hurt others in a suicide (OR=4.22; 95% Cl=1.60, 11.15) but less likely to report depression (OR = 0.63; 95% Cl = 0.48, 0.83), to have a family history of suicide (OR = 0.08; 95% Cl=0.01, 0.61), or to leave a suicide note (OR=0.37; 95% Cl=0.26, 0.52). Conclusions. Future research should consider that Black suicide decedents are less likely to report depression than White suicide decedents. This suicide risk difference is important when developing effective suicide prevention programs.

Published
2008

27. Characteristics of Black and White suicide decedents in Fulton County, Georgia, 1988-2002

Author

Abe, Karon, Mertz, Kristen J., Powell, Kenneth E., and Hanzlick, Randy L.

Subjects
Prevalence studies (Epidemiology) -- Comparative analysis, Racism -- Risk factors, Suicide -- Causes of, Government, Health care industry
Abstract

Objectives. We compared the prevalence of risk factors for Black and White suicide decedents in Fulton County, Georgia, from 1988-2002. Methods. We used data from the Fulton County Medical Examiner's Office to compile information on suicides that occurred in Fulton County between 1988 and 2002. We used the [chi square] test and logistic regression to identify associations between suicide risk factors and race. Results. Black suicide decedents were more likely than White suicide decedents to be male (odds ratio [OR]= 2.06; 95% confidence interval [CI] = 1.38, 3.09), to be younger, ([less than or equal to] Conclusions. Future research should consider that Black suicide decedents are less likely to report depression than White suicide decedents. This suicide risk difference is important when developing effective suicide prevention programs.

Published
2006

28. Cancer‐associatedvenous thromboembolism: Incidence and features in a racially diverse population

Author

Raskob, Gary E., Wendelboe, Aaron M., Campbell, Janis, Ford, Lance, Ding, Kai, Bratzler, Dale W., McCumber, Micah, Adamski, Alys, Abe, Karon, Beckman, Michele G., Reyes, Nimia L., and Richardson, Lisa C.

Abstract

Data on the population‐based incidence of cancer‐associated venous thromboembolism (VTE) from racially diverse populations are limited. To evaluate the incidence and burden of cancer‐associated VTE, including demographic and racial subgroups in the general population of Oklahoma County—which closely mirrors the United States. A population‐based prospective study. We conducted surveillance of VTE at tertiary care facilities and outpatient clinics in Oklahoma County, Oklahoma, from 2012–2014. Surveillance included reviewing all imaging reports used to diagnose VTE and identifying VTE events from hospital discharge data and death certificates. Cancer status was determined by linkage to the Oklahoma Central Cancer Registry. We used Poisson regression to calculate crude and age‐adjusted incidence rates of cancer‐associated VTE per 100 000 general population per year, with 95% confidence intervals (95% CI). The age‐adjusted incidence (95% CI) of cancer‐associated VTE among adults age ≥ 18 was 70.0 (65.1–75.3). The age‐adjusted incidence rates (95% CI) were 85.9 (72.7–101.6) for non‐Hispanic Blacks, 79.5 (13.2–86.5) for non‐Hispanic Whites, 18.8 (8.9–39.4) for Native Americans, 15.6 (7.0–34.8) for Asian/Pacific Islanders, and 15.2 (9.2–25.1) for Hispanics. Recurrent VTE up to 2 years after the initial diagnosis occurred in 38 of 304 patients (12.5%) with active cancer and in 34 of 424 patients (8.0%) with a history of cancer > 6 months previously. Age‐adjusted incidence rates of cancer‐associated VTE vary substantially by race and ethnicity. The relatively high incidence rates of first VTE and of recurrence warrant further assessment of strategies to prevent VTE among cancer patients.

Published
2022
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30. Cancer- Associated Venous Thromboembolism (VTE) Characteristics in Blacks Compared to Whites in Durham County, North Carolina

Author

Saber, Ibrahim, primary, Kuchibhatla, Maragatha, additional, Adamski, Alys, additional, Richardson, Lisa C., additional, Reyes, Nimia, additional, Abe, Karon, additional, Beckman, Michele G, additional, Thames, Elizabeth, additional, Singh, Bhavana, additional, Sitlinger, Andrea, additional, Schulteis, Ryan, additional, and Ortel, Thomas L., additional

Published
2019
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36. Awareness of Cardiovascular Disease Risk in American Indians

Author

Baldyga, William, Petersmarck, Karen, Martin, Maurice W, Martin, Sarah, Elmer, Elmer Ray, Oser, Carrie S, Blades, Lynda, Strasheim, Carol, Helgerson, Steven, Gohdes, Dorothy, Harwell, Todd, Link, Michael W, Mokdad, Ali, Stackhouse, Herbert, Flowers, Nicole, Kempf, Angela M, Remington, Patrick L, Peppard, Paul E, Dranger, Elizabeth A, Kindig, David A, Hannon, Peggy A, Harris, Jeffrey, Martin, Diane, VanEenwyk, Juliet, Bowen, Deborah, Agron, Peggy, Berends, Victoria, Benard, Vicki B, Lawson, Herschel, Eheman, Christie, Anderson, Christa, Helsel, William, Bretthauer-Mueller, Rosemary, Melancon, Heidi, Krishna, Ranjitha, Liff, Jonathan, Chen, Amy, Eke, Paul, Valerie, Robison, Snyder, Susan J, Belza, Basia, Maltese, Joy N, Brewton, Cary, Arroyo, Cassandra, Jones, Dennis, Liu, Yong, Din-Dzietham, Rebecca, Davis, Sharon, Plescia, Marcus, Groblewski, Martha, Krapfl, R. Heidi, Croft, Janet, Russell Doran, Donna, Gold, Jeffrey, Serbaroli, Francis, Hannan, Edward L, Macielak, Paul F, Streck, William F, Jones, Kari A, Griffin, Susan, Moonesinghe, Ramal, Jaramillo, Freder, Vousden, Claudia, Kruger, Judy, Kealey, Melissa, Hunter, Rebecca, Ivey, Susan, Satariano, William, Bayles, Constance, Brennan Ramirez, Laura, Bryant, Lucinda, Johnson, Courtney, Lee, Chanam, Levinger, David, McTigue, Kathleen, Moni, Gwen, Vernez Moudon, Anne, Pluto, Delores, Prohaska, Thomas, Sible, Christen, Tindal, Sabrina, Wilcox, Sara, Winters, Kendra, Williams, Kathy, Bagdonas, Sylvia, Mueller, Niki, Russian, Amy, Cyzman, Denise R, Bour, Norma, McLaury, Rachel, Lyles, Judith, Berlin, Michelle, Waxman, Judith, Osborne, Richard H, Hawkins, Melanie, Caito, Nikki M, Elliott, Michael, Lovegreen, Sarah, Klump, Paula, Kreuter, Matthew W, Brownson, Ross, Fernandez, Maria E, Torres, Isabel, Vernon, Sally, Byrd, Theresa, Hinjosa-Lindsey, Marilyn, Wippold, Rosario, Bains, Yadvindera, Moy, Ernest, Arispe, Irma, Holmes, Julia, Khan Hadi, Erum, Jaar-Marzouka, Sabrina, Hiemke, Trina, Cardinale, Lisa, Armour, Brian, Pitts, M. Melinda, Lee, Chung-won, Woollery, Trevor, Caraballo, Ralph, Abe, Karon, Mertz, Kristen, Powell, Kenneth, Wu, Manxia, Cho, Pyone, Whitelaw, Nancy A, Erckenbrack, Nancy, Schreiber, Robert, Simmons, June, Wilson, Nancy, Hudson Collins, Paula, Fleming-Moran, Millicent, Li, Kaigang, Gibson, Joseph, and Garland, Miriam

Subjects
EDITORIAL: FEATURED ABSTRACTS FROM THE 19th NATIONAL CONFERENCE ON CHRONIC DISEASE PREVENTION AND CONTROL, Biomedical Research, Special Topics, Neoplasms, Original Research: Featured Abstract from the 19th National Conference on Chronic Disease Prevention and Control, Humans, Community Case Study, Community Networks, United States
Abstract

The Cancer Prevention and Control Research Network is a national network recently established to focus on developing new interventions and disseminating and translating proven interventions into practice to reduce cancer burden and disparities, especially among minority and medically underserved populations. Jointly funded by the Centers for Disease Control and Prevention and the National Cancer Institute, the Cancer Prevention and Control Research Network consists of sites administered through Prevention Research Centers funded by the Centers for Disease Control and Prevention. The five sites are located in Kentucky, Massachusetts, South Carolina, Texas, Washington State, and West Virginia. The Cancer Prevention and Control Research Network's intervention areas include primary prevention of cancer through healthy eating, physical activity, sun avoidance, tobacco control, and early detection of cancer through screening. The Cancer Prevention and Control Research Network uses the methods of community-based participatory research and seeks to build on the cancer-relevant systematic reviews of the Guide to Community Preventive Services. Initial foci for the Cancer Prevention and Control Research Network's research work groups include projects to increase screening for breast, cervical, and colorectal cancers; to promote informed decision making for prostate cancer screening; and to validate educational materials developed for low-literacy populations.

Published
2005

41. Dependence of Dbl and Dbs Transformation on MEK and NF-?B Activation

Author

Whitehead, Ian P., Lambert, Que T., Glaven, Judith A., Abe, Karon, Rossman, Kent L., Mahon, Gwendolyn M., Trzaskos, James M., Kay, Robert, Campbell, Sharon L., and Der, Channing J.

Abstract

ABSTRACTDbs was identified initially as a transforming protein and is a member of the Dbl family of proteins (>20 mammalian members). Here we show that Dbs, like its rat homolog Ost and the closely related Dbl, exhibited guanine nucleotide exchange activity for the Rho family members RhoA and Cdc42, but not Rac1, in vitro. Dbs transforming activity was blocked by specific inhibitors of RhoA and Cdc42 function, demonstrating the importance of these small GTPases in Dbs-mediated growth deregulation. Although Dbs transformation was dependent upon the structural integrity of its pleckstrin homology (PH) domain, replacement of the PH domain with a membrane localization signal restored transforming activity. Thus, the PH domain of Dbs (but not Dbl) may be important in modulating association with the plasma membrane, where its GTPase substrates reside. Both Dbs and Dbl activate multiple signaling pathways that include activation of the Elk-1, Jun, and NF-?B transcription factors and stimulation of transcription from the cyclin D1 promoter. We found that Elk-1 and NF-?B, but not Jun, activation was necessary for Dbl and Dbs transformation. Finally, we have observed that Dbl and Dbs regulated transcription from the cyclin D1 promoter in a NF-?B-dependent manner. Previous studies have dissociated actin cytoskeletal activity from the transforming potential of RhoA and Cdc42. These observations, when taken together with those of the present study, suggest that altered gene expression, and not actin reorganization, is the critical mediator of Dbl and Rho family protein transformation.

Published
1999
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42. Outbreak of Burkholderia cepaciaBloodstream Infection at an Outpatient Hematology and Oncology Practice

Author

Abe, Karon, D'Angelo, Melissa Tobin, Sunenshine, Rebecca, Noble-Wang, Judith, Cope, James, Jensen, Bette, and Srinivasan, Arjun

Abstract

We investigated an outbreak of infection in 10 patients with blood cultures positive for B. cepacia. All patients had indwelling intravenous catheters. Though we did not identify the source of the organism, our findings support the hypothesis that cross-contamination of multidose medications through the use of the same needle and syringe was a contributing factor.

Published
2007
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