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The aim of this document is to share the action plan from the young Italian Association of Radiotherapy and Clinical Oncology (yAIRO). We believe it is important to enhance a constructive dialog between societies. The hope is to offer to young radiation oncologists a wealth of opportunities to refine their skills and gain access to the latest developments, according to a shared European vision.

Introduction differential diagnosis of tumor recurrence and radiation injury after stereotactic radiotherapy (SRT) is challenging. The advances in imaging techniques and feature-based radiomics could aid to discriminate radionecrosis from progression. Methods we performed a systematic review of current literature, key references were obtained from a PubMed query. Data extraction was performed by 3 researchers and disagreements were resolved with a discussion among the authors. Results we identified 15 retrospective series, one prospective trial, one critical review and one editorial paper. Radiomics involves a wide range of imaging features referred to necrotic regions, rate of contrast-enhancing area or the measure of edema surrounding the metastases. Features were mainly defined through a multistep extraction/reduction/selection process and a final validation and comparison. Conclusions feature-based radiomics has an optimal potential to accurately predict response and radionecrosis after SRT of BM and facilitate differential diagnosis. Further validation studies are eagerly awaited to confirm radiomics reliability., Graphical abstract Image, graphical abstract

Purpose The purpose of this study was to characterize the Mobius AIRO Mobile CT System for localization and image-guided proton therapy. This is the first known application of the AIRO for proton therapy. Methods Five CT images of a Catphan®504 phantom were acquired on the AIRO Mobile CT System, Varian EDGE radiosurgery system cone beam CT (CBCT), Philips Brilliance Big Bore 16 slice CT simulator, and Siemens SOMATOM Definition AS 20 slice CT simulator. DoseLAB software v.6.6 was utilized for image quality analysis. Modulation transfer function, scaling discrepancy, geometric distortion, spatial resolution, overall uniformity, minimum uniformity, contrast, high CNR, and maximum HU deviation were acquired. Low CNR was acquired manually using the CTP515 module. Localization accuracy and CT Dose Index were measured and compared to reported values on each imaging device. For treatment delivery systems (Edge and Mevion), the localization accuracy of the 3D imaging systems were compared to 2D imaging systems on each system. Results The AIRO spatial resolution was 0.21 lp mm−1 compared with 0.40 lp mm−1 for the Philips CT Simulator, 0.37 lp mm−1 for the Edge CBCT, and 0.35 lp mm−1 for the Siemens CT Simulator. AIRO/Siemens and AIRO/Philips differences exceeded 100% for scaling discrepancy (191.2% and 145.8%). The AIRO exhibited higher dose (>27 mGy) than the Philips CT Simulator. Localization accuracy (based on the MIMI phantom) was 0.6° and 0.5 mm. Localization accuracy (based on Stereophan) demonstrated maximum AIRO-kV/kV shift differences of 0.1 mm in the x-direction, 0.1 mm in the y-direction, and 0.2 mm in the z-direction. Conclusions The localization accuracy of AIRO was determined to be within 0.6° and 0.5 mm despite its slightly lower image quality overall compared to other CT imaging systems at our institution. Based on our study, the Mobile AIRO CT system can be utilized accurately and reliably for image-guided proton therapy.

Our purpose in this article is to study the figure of Clemente Airó as publisher of Espiral, a Colombian magazine about arts and literature (1944-1975). Our question is how he built another kind of artistic definition in comparison with Marta Traba’s approach., En nuestro artículo estudiamos el rol de Clemente Airó como editor en la revista colombiana de artes y letras Espiral (1944-1975). Nos preguntamos por su relación con otras definiciones de canon artístico en la época, comparado con la crítica argentina Marta Traba.

Purpose: Current solutions for navigated spine surgery remain hampered by restrictions in surgical workflow as well as a limited versatility and applicability. Against this background, we report the first experience of navigated spinal instrumentation with the mobile AIRO® intraoperative computed tomography (iCT) scanner. Methods: AIRO® iCT was used for navigated posterior spinal instrumentation of 170 screws in 23 consecutive patients operated on in our Department between the first use of the system in May 2014 and August 2014. The indications for AIRO® were based on the surgical region, anatomical complexity and the need for >3 segment instrumentation. Following navigated screw insertion, screw positions were confirmed intraoperatively by a second iCT scan. CT data on screw placement accuracy were retrospectively reviewed and analyzed by an independent observer. Results: AIRO®-based spinal navigation was easy to implement and successfully accomplished in all patients, adding around 18–34 min to the net surgery time. A systematic description of the authors’ approach, setup in the OR and workflow integration of the AIRO® is presented. Analysis of screw placement accuracy revealed 9 (5.3 %) screws with minor pedicle breaches (2 mm, resulting in an accuracy rate of 95.9 %. Conclusions: The AIRO® system is an easy-to-use and versatile iCT for navigated spinal instrumentation and provides high pedicle screw accuracy rates. Although the authors’ experience suggests that the learning curve associated with AIRO®-based spinal navigation is steep, a systematic user-based approach to the technology is required.

Itsenäistymisen alkuvuosina Suomen armeijan liikekannallepano perustui saksalaisilta perittyyn kaaderiperustamiseen. Järjestelmä todettiin pian suomalaisiin olosuhteisiin liian raskaaksi ja hitaaksi. Kaaderiperustamisessa perustaminen tapahtui joukko-osastoissa. Joukko-osaston tuli samanaikaisesti suojata liikekannallepanoa ja suorittaa reserviläisten liikekannallepano. Myöhemmin armeija jaettiin suojajoukkoon ja kenttäarmeijaan tämän epäkohdan poistamiseksi. Kenttäarmeijan perustamista varten kehitettiin aluejärjestelmä ja sen toimeen-panijaksi aluejärjestö. Aluejärjestelmä otettiin käyttöön toukokuun alussa 1934. Aluejärjes-telmän kehittäjästä on ollut erilaisia mielipiteitä. Osa tutkijoista on pitänyt Aksel Fredrik Airoa aluejärjestelmän kehittäjänä ja osa Leonard Grandellia. Tutkitun materiaalin perusteella aluejärjestelmä oli Leonard Grandellin kehitystyön tulos.