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Aim To investigate the value of ultrasound in the diagnosis of congenital internal carotid artery hypoplasia (CICAH). Methods Patients diagnosed with CICAH by ultrasound in Baotou Central Hospital, Inner Mongolia from July 2022 to December 2023 were retrospectively collected. The general data, ultrasound and imaging data of all patients were recorded. Results Among the 25 317 carotid artery ultrasonography subjects, 13 patients were diagnosed as CICAH. The ultrasonic detection rate of CICAH was 0. 051%. The 13 cases of CICAH included 11 cases of unilateral internal carotid artery hypoplasia and 2 cases of bilateral internal carotid artery hypoplasia. CT scan of carotid canal confirmed that all 13 cases of internal carotid artery hypoplasia were unilateral lesions, among which 2 cases of unilateral lesions were misdiagnosed as bilateral lesions by ultrasound, with a misdiagnosis rate of 15%. Taking carotid canal dysplasia as the gold standard, ROC curve was plotted to evaluate the diagnostic value of ultrasound in CICAH. The area under the curve (AUC) was 0. 941, and the optimal diagnostic threshold value of CICAH was 3. 2 mm, sensitivity was 100%, and specificity was 85%. The consistency test between ultrasonic examination and gold standard test method for CT scanning of carotid artery canal showed that Kappa value was 0. 846. Conclusion Ultrasound has a high diagnostic value in the diagnosis of CICAH, and can be used as the first choice of clinical examination. [ABSTRACT FROM AUTHOR]

Copyright of Science & Technology of Food Industry is the property of Science & Technology of Food Industry Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

【摘要】 目的 探讨品管圈活动在降低卒中患者住院期间便秘发生率中的应用及维持效果。 方法 在山东大学附属省立医院神经内科开展品管圈活动，针对神经内科住院卒中患者便秘发生率高的原因进行查检、分析及改进，改进措施实施一个月后，对实施品管圈活动前后卒中患者便秘发生率进行比较。半年后将改善措施推广至保健神经内科，比较实施推广一个月后保健神经内科卒中患者便秘发生率的变化。 结果 改善前调查神经内科170例缺血性卒中患者，改善后调查142例缺血性卒中患者，神经内科卒中患者便秘发生率由改善前的67.64%降低到改善后的27.46%，差异有统计学意义（χ2=49.98，P

Copyright of China Rural Water & Hydropower is the property of China Rural Water & Hydropower Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

ABCG2 and SLC2A9 encode the uric acid transporters ABCG2 and GLUT9. ABCG2 single nucleotide polymorphism (SNP) can reduce the expression and transport function of ABCG2 protein, and then cause intestinal uric acid excretion dysfunction, resulting in the increase of blood uric acid. The regulation of blood uric acid by SLC2A9 is complicated. Loss of function of SLC2A9 may lead to decreased renal tubule uric acid reabsorption, impaired intestinal uric acid excretion and impaired hepatic uric acid uptake. ABCG2 promotes gout attacks by causing hyperuricemia(HUA) and increasing inflammatory responses. On the contray, loss of function of SLC2A9 can instead reduce oxidation and inflammatory responses. In addition, ABCG2 has a close relationship with early-onset gout and its SNP is a risk factor for early onset gout. [ABSTRACT FROM AUTHOR]

Copyright of South Architecture / Nanfang Jianzhu is the property of South Architecture Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Rural Water & Hydropower is the property of China Rural Water & Hydropower Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To explore the beliefs and attitudes about sleep in patients with comorbid depressive disorder and insomnia, and to explore its influence on sleep quality. Methods Patients with comorbid depressive disorder and insomnia (n=61) and patients with primary insomnia (n=62) who met criteria specified in the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) in Beijing Anding Hospital Affiliated to Capital Medical University were enrolled, meantime, another 64 healthy controls were recruited. All subjects were assessed using Dysfunctional Beliefs and Attitudes about Sleep (DBAS) and Pittsburgh Sleep Quality Index (PSQI) . Additionally, patients with comorbid depressive disorder and insomnia were evaluated using Hamilton Depression Scale-17 item (HAMD-17) . The PSQI and DBAS scores were compared among three groups using analysis of covariance, and multiple linear regression analysis was used to screen the factors affecting PSQI score in patients with comorbid depressive disorder and insomnia. Results Compared with healthy controls, higher scores of PSQI (t=18. 932, 18. 610, P<0. 01) along with lower scores of DBAS (t=-5. 561, -5. 791, P<0. 01) were observed in patients with comorbid depressive disorder and insomnia and patients with primary insomnia. Taking the PSQI score of patients with comorbid depressive disorder and insomnia as the dependent variable, statistically significant equations were generated using multiple linear regression analysis (F=14. 095, R² =0. 327, P<0. 05), and the predictive and control factors of sleep in DBAS and age were found to be the influencing factors of PSQI score in patients (B=-0. 100, -0. 279, P<0. 05 or 0. 01) . Conclusion Compared with the normal, depression patients with insomnia have more dysfunctional beliefs and attitudes towards sleep, and dysfunctional cognition may be the influencing factor of their sleep quality. [ABSTRACT FROM AUTHOR]

Firstly, the metabolites in plasma were extracted to obtain organic and aqueous phases by Folch method. Several kinds of metabolites in organic and aqueous phases were detected simultaneously by ultra-performance liquid chromatography-high resolution mass spectrometry (UPLC-HRMS). Mobile phase and elution procedure were optimized. Chromatographic separation was performed on a ACE3 C18 column (150 mm×3.0 mm×3.0 μm), and the MS analysis was carried out by electrospray ionization (ESI) source in positive and negative ion modes combined with full and segmental scanning. The mass spectrometry-based molecular networking (MSMN) has been widely used, but it has not been mentioned in the analysis of lipid metabolites. In this study, the method for the analysis of metabolites in plasma by UPLC-HRMS combined with MSMN was developed. The metabolites identified by chemical standards were selected as seed compounds, and MSMN was used to screen the metabolites having similar MS/MS behavior with the seed compounds, so as to expand the qualitative range and improve the qualitative efficiency of metabolites. A total of 187 metabolites were annotated, including 80 metabolites such as amino acid, fatty acid and sugar in the aqueous phase and 107 lipid metabolites in the organic phase, among which 64 metabolites were identified by MSMN, which achieved the high throughput analysis of multiple metabolites in human plasma in this way. It provided a feasible new idea for the identification of lipid metabolites but there were still many limitations and challenges. The MSMN is suitable for the analysis of metabolites with large molecular weight, and the prerequisite is that the MS/MS of certain metabolites contains at least 3 or more common characteristic fragments. In this work, the metabolites identified by MSMN in the organic phase were mostly phosphatidylcholines (PCs) and sphingomyelins (SMs) in positive ion mode. For example, the aggregation degree of triacylglycerols (TGs) was high in the MSMN, but it was difficult to annotate successfully because of the weak characteristic of common fragments. However, in negative ion mode, it was more difficult to use MSMN to characterize the metabolites because of the small number of characteristic fragments of congener metabolites and the low mass spectral response of some fragments, which was difficult to be detected. We also tried to establish the MSMN of metabolites in the aqueous phase and obtained the molecular network diagram with good aggregation. However, the qualitative results were not satisfactory, and the metabolites in the aqueous phase were all small molecular weight metabolites such as amino acid, and the MS/MS lacked representative characteristic fragments, so MSMN was not suitable for these metabolites. [ABSTRACT FROM AUTHOR]

In order to explore the nutritional and health value of buckwheat varieties, the variation of crude protein, total flavonoids, protein components and fruit characters of 56 different lines of buckwheat seeds were studied. The results were as follows:(1)Common buckwheat, rice tartary buckwheat and golden tartary buckwheat seeds had crude protein content average of 13.19%, 15.44% and 11.75%, respectively, total flavonoids average of 0.14%, 2.50%, and 2.09%, the average of albumin content of 5.22%, 6.13% and 4.56%, respectively, the average of globulin content of 1.29%, 1.15%, and 0.91%, respectively, the average of gliadin content of 0.42%, 0.58%, and 0.55%, respectively, and the average of glutenin content of 2.66%, 3.36%, and 2.80%, respectively. The protein component content orders of all types of buckwheat were in accordance with albumin > glutenin > globulin > gliadin.(2)Among the fruit traits, the variation coefficient of 1 000-fruit weight, fruit area and diameter of common buckwheat were the largest, and the variation coefficient of fruit perimeter, fruit length-width ratio, fruit length, fruit width and 50 mL volumetric weight of rice tartary buckwheat fruit were the largest.(3)Correlation analysis showed that there are significant or extremely significant correlations between crude protein content and length-width ratio and fruit length in common buckwheat, between crude protein content and fruit perimeter and fruit length in golden buckwheat, between crude protein content and fruit width, between total flavonoids content and fruit area, fruit width, fruit diameter and 50 mL volumetric weight in rice tartary buckwheat fruits.(4)Through the study, the buckwheat lines with high protein content or high flavonoid content, such as common buckwheat Guitian 1808-166, golden tartary buckwheat(Duoku74, Duoku78),black rice buckwheat(1906-136 and 43-2)were found. The results in this study have some guiding significance for the quality breeding of buckwheat and the development of new buckwheat products. [ABSTRACT FROM AUTHOR]

Copyright of Railway Investigation & Surveying is the property of Railway Investigation & Surveying Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In order to study the effects of sowing seasons and planting methods on the main agronomic traits of perennial tartary buckwheat, six new perennial tartary buckwheat lines(Fagopyrum tatari-cymosum)were selected to investigate the main agronomic traits under seed sowing and autumn regeneration. The results were as follows:(1)The effects of different sowing seasons on pollen fertility, total seed set, effective rate of seed set, plant height, main stem diameter, main stem branching number, main stem node number, 100-grain weight, grain number per plant and yield of main inflorescence of new perennial tartary buckwheat lines reached signi-ficant or extremely significant level. Fertility rate of main inflorescence, total seed set, effective rate of seed set, number of branches of main stem, 100-grain weight, grain number per plant and yield per plant under autumn sowing were extremely significantly higher than those under spring sowing; Plant height, diameter of main stem and number of nodes of main stem under autumn sowing were extremely significantly lower than those under spring sowing; There was no significant differences in the size of main inflorescence flowers and the ratio of length to width of ten grains.(2)The effects of different planting methods on pollen fertility and effective rate of seed set on main inflorescence, number of main stem nodes and 100-grain weight of plant reached signi-ficant or extremely significant level; The fertility rate of regeneration main inflorescence pollen and the grain number per plant in autumn are significantly higher than those of autumn sowing; The effective rate of seed set on main inflorescence, the diameter of main stem, number of main stem nodes and 100-grain number of plant are significantly lower than those of autumn sowing. There are no significant differences in the size of main inflorescence flowers, the total seed set, plant height, number of main stem branches, length-width ratio of grain and yield per plant; The correlation analysis showed that there were the highest correlation coefficient between the effective rate of seed set of main inflorescence and grain number per plant with yield per plant in each growing season.(3)Among all the tested lines, the autumn sowing yield per plant of 1612-241 was significantly higher than that of other lines, and the autumn regeneration yield per plant of 1612-16 and 1612-33 were significantly higher than that of the normal season. The results of this study are helpful to obtain the best lines suitable for sowing on one season and harvesting in two seasons, and provide clues for the perennial tartary buckwheat breeding in the future. [ABSTRACT FROM AUTHOR]