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Presents the proceedings of the British Pharmacological Society on drug metabolism in Great Britain. Analysis on the study of CYP2D6 polymorphism in relation to lung cancer and Parkinson's disease; Effects on the bioactivation of sulphamethoxazole; Structure of drug metabolism.

Describes the progress of clinical pharmacology in Great Britain over the last 20 years as of 2003. Contribution of B.B. Brodie, pharmacologist at the National Institute of Health on drug metabolism; Realization of adverse effect of racemates in the 1980s by pharmacologist E.J. Ariëns; Change in perception toward drug metabolism and its contribution to presystemic elimination.