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The southwest vortex (SWV) is a critical weather system in China, but our knowledge of this system remains incomplete. Here, we investigate the cloud properties in the SWV. First, we search for the SWVs with time steps and center locations that are consistent between the SWV yearbook and ERA-Interim reanalysis data. Second, we supplement these SWVs' life spans and movement paths. Third, we relocate the Fengyun (FY) satellite FY-4A cloud retrievals in the 10° × 10° region centered on each SWV and analyze the cloud occurrence frequency (COF), cloud-top height (CTH), and cloud optical thickness (COT). A distribution mode of cloud types is summarized from the COFs, with water clouds, supercooled clouds, mixed clouds, ice clouds, cirrus clouds, and overlap clouds occurring sequentially from west to east. The CTH probability density (PD) distribution features a significant north–south difference. In addition, the COT PD distributions exhibit a common trend: with increasing COT, the PD increases rapidly and then slowly before peaking, whereupon the PD decreases abruptly. From spring to summer, the region with the highest convective COF shifts from the northeast to the northwest, and an east–west gradient of the convective COF appears in autumn and winter. Furthermore, we investigate the cloud properties during SWV-related heavy rainfall. Heavy rain occurs mainly in the west of the SWV, and convective clouds are mainly in the northwest, partly in the southwest and near the SWV center. The average CTH in heavy rainfall is generally higher than 6 km, and the average COT is greater than 20. Significance Statement: The southwest vortex (SWV) is an important weather system in China. However, we do not yet comprehensively know this weather system. The cloud properties can indicate the structures of weather systems and are key parameters in numerical weather prediction (NWP) models. Thus, investigating cloud properties is necessary and meaningful to understand the SWV and accurately predict SWV-related precipitation in NWP models. In this paper, a typical distribution mode of six cloud types in the SWV is summarized from the cloud occurrence frequency, and the distribution features of convective clouds, cloud-top height, and cloud optical thickness in the SWV are analyzed. Furthermore, the cloud properties in SWV-related heavy rain are also studied. [ABSTRACT FROM AUTHOR]

Objective: Previous studies have shown that there are significant regional and gender differences in the association between the phenotype of short stature and diabetes mellitus (DM). The purpose of this study was to investigate the gender difference between the phenotype of short stature and the risk of DM in the Chinese population. Methods: The sample included 116,661 adults from 32 locations of 11 cities in China, of which the average height of men and women was 171.65 and 160.06 cm, respectively. Investigators retrospectively reviewed annual physical examination results for follow-up observations and set confirmed DM events as the outcome of interest. Multivariate Cox regression, restricted cubic spline, and piecewise regression models were used to check the association between height and DM risk. Results: During an average observation period of 3.1 years, there were 2,681 of 116,661 participants who developed new-onset DM, with a male to female ratio of 2.4 to 1. After full adjustment for confounders, we confirmed that there was a significant negative correlation between height and DM risk in Chinese women (HR per 10 cm increase: 0.85, 95% CI: 0.74–0.98), but not in men (HR per 10 cm increase: 1.16, 95% CI: 0.98–1.14). Additionally, through restricted cubic spline and piecewise regression analysis, we determined that the height of 157–158 cm may be the critical point for short stature used to assess the risk of DM in Chinese women. Conclusions: In the Chinese population, female short stature phenotype is related to increased DM risk, among which 157–158 cm may be the saturation effect point of female short stature for predicting DM risk. [ABSTRACT FROM AUTHOR]

Aims/Introduction: Although the efficacy of teneligliptin, a highly selective dipeptidyl peptidase‐4 inhibitor, has been amply studied for the treatment of type 2 diabetes, no clinical trials of teneligliptin have been carried out in China. We evaluated the efficacy and safety of teneligliptin monotherapy compared with a placebo in Chinese patients with type 2 diabetes mellitus inadequately controlled with diet and exercise. Materials and Methods: This multicenter, randomized, double‐blind, placebo‐controlled, parallel‐group study, carried out at 42 sites, enrolled type 2 diabetes patients with glycosylated hemoglobin 7.0 to <10.0% and fasting blood glucose <270 mg/dL. Patients were randomly assigned, in a 1:1 ratio, to treatment with 20 mg teneligliptin or a placebo (n = 127, each) administered orally once daily before breakfast for 24 weeks. Change in glycosylated hemoglobin from baseline to week 24 was the primary efficacy end‐point. Safety was assessed by the incidence of adverse events and adverse drug reactions. Results: The least square mean (LSM) change in glycosylated hemoglobin from baseline to week 24 was −0.95% with teneligliptin versus −0.14% with a placebo, yielding an LSM difference (teneligliptin vs placebo) of −0.80% (P < 0.0001). For the secondary end‐point, from baseline to week 24, the LSM change in fasting blood glucose was −21.9 mg/dL with teneligliptin versus −1.4 mg/dL with a placebo, yielding an LSM difference (teneligliptin vs placebo) of −20.5 mg/dL (P < 0.0001). The adverse event and adverse drug reaction incidence rates, including hypoglycemia, were similar in both groups. Conclusions: At 24 weeks, teneligliptin was generally well tolerated and effective in Chinese patients with type 2 diabetes mellitus inadequately controlled with diet and exercise. [ABSTRACT FROM AUTHOR]

This study investigates the characteristics of the heterogeneous carbonate reservoir of Majiagou Formation in Jingxi area, Ordos Basin, China, to explain the diagenetic control and distribution of high‐quality reservoir intervals. The carbonates of the study area mainly consist of silt‐sized crystalline dolomite, microcrystalline dolomite, and microcrystalline limey dolomite. Both dolomite content and dolomite size gradually decrease both from top to bottom and from slope to basin. Intercrystalline pores exist in the silt‐sized crystalline dolomite, and vuggy pores and fractures mainly developed in microcrystalline (limey) dolomite. Furthermore, typical geopetal infills and three stages of calcite cements could be differentiated. Based on petrographical and geochemical analysis, the reservoir is dominantly controlled by seepage reflux dolomitization and telogenetic karstification. Four reservoir evolutions could be differentiated. The reservoir in the first model is dominated by intercrystal porosity occurring in silt‐sized crystalline dolostone. It experienced strong dolomitization, telogenetic karstification, and shallow as well as deep burial cementation. The reservoir in the second model consists of only a small amount of high‐angle dissolution fissures and vertical dissolution cavities in microcrystalline (limey) dolostone. It experienced relatively weak dolomitization, strong telogenetic karstification, and two important calcite cementation events. The reservoir in the third model is marked by many vuggy pores and dissolution fractures, occurring in microcrystalline (limey) dolostone. The strata experienced relatively weak dolomitization, strong telogenetic karstification, and two weak calcite cementation episodes. The reservoir in the fourth model is dominated by fractures and their related dissolution pores, which developed in microcrystalline (limey) dolostone. These dolostones experienced relatively weak dolomitization, telogenetic karstification, and calcite cementation. From a reservoir point of view, the reservoirs represented by the first and third models, which respectively are composed of silt‐sized crystalline dolomite occurring in the top of the whole dolostone succession and the dolomite affected by telogenetic karstification, are the most vital exploration targets. [ABSTRACT FROM AUTHOR]

The Dongpu Depression, containing huge amounts of hydrocarbons, is a typical petroliferous province in the Bohai Bay Basin, east China. As one set of the main source rocks, the first member of Shahejie Formation (E2s1) shows huge exploration potential with approximately 0.83 × 108 t resources remaining to be discovered. However, the geochemical characteristics and thermal evolution history of E2s1 source rocks have still not been determined. In this study, the sedimentary features were firstly analysed based on the geological data. Then the organic matter abundance, kerogen type, and thermal maturity of E2s1 source rocks in the present day were evaluated according to the Rock‐Eval pyrolysis, micro‐components of kerogen, total organic carbon (TOC), and vitrinite reflectance analysis. Furthermore, the evolution of thermal history and hydrocarbon generation was determined using the PetroMod procedure. The results show that dark mudstones and salt rocks were well developed in E2s1, which are propitious for organic matter to grow and preserve. E2s1 source rocks contain abundant organic matter and moderate to good generative source rock potential. E2s1 source rocks mainly consist of Type II kerogen and have entered early to maturation stage for hydrocarbon generation. Due to the limited buried depth, E2s1 source rocks only attained lower thermal maturity and generated finite hydrocarbons. The initial rapid subsidence and the second rift after uplift erosion resulted in the higher geo‐temperature at the end of E3d and the present day. Corresponding to the geo‐temperature evolution, there are two stages of hydrocarbon generation for E2s1 source rocks: The first stage was in the late E3d period, and the late stage was from the late Neogene to the present day. Moreover, the hydrocarbon generation rate and quantity of the late stage are much higher than the first stage, indicating the major hydrocarbon generation stage. Due to the limited hydrocarbon generation capacity, oils generated from E2s1 source rocks are low maturity; thus, it cannot migrate for a long distance and only accumulated around the sag belts. [ABSTRACT FROM AUTHOR]

This study aimed to examine the psychometric properties of the Multicomponent Mental Health Literacy Scale (MMHLS) among Chinese elite athletes. Particularly, the factorial validity, convergent validity, discriminant validity, concurrent validity, internal-consistency reliability, and test-retest reliability of the MMHLS were examined. A total of 320 participants were recruited from the Guangdong provincial sports training center in China. Data collection was conducted between 30 June and 31 July 2020 using electronic questionnaires. Confirmatory factor analysis (CFA), Rasch analysis, correlation analysis and independent-sample t -tests were conducted using Mplus 8.3 and ConQuest 2.0. The CFA results supported the factorial validity of the three-dimensional MMHLS, consisting of knowledge-oriented MHL, beliefs-oriented MHL, and resource-oriented MHL. Cronbach's alpha and composite reliability coefficients supported the internal-consistency reliability of the MMHLS. Moreover, the convergent and discriminant validities were supported for the subdimension of MHL-Knowledge, MHL-Beliefs, and MHL-Resources. Concurrent validity was demonstrated through correlations between MMHLS, help-seeking attitudes, and stigma. Rasch analysis provided further evidence of the psychometric quality of the instrument in terms of its dimensionality, item fit statistics, and rating scale effectiveness. Finally, test-retest reliability was 0.66 after one month. In conclusion, the 24-item three-dimensional MMHLS was verified to be a reliable and valid measurement of mental health literacy in Chinese elite athletes.

Background: Triglyceride glucose-body mass index (TyG-BMI) has been proven to be a reliable substitute for insulin resistance. However, whether a causal association exists between TyG-BMI and new-onset diabetes remains uncertain. The purpose of this study was to investigate the causal association and predictive performance between TyG-BMI and diabetes., Methods: A total of 116,661 subjects who underwent a physical examination were included in this study. The subjects were divided into five equal points according to the quintile of TyG-BMI, and the outcome of interest was the occurrence of diabetic events. TyG-BMI = ln [fasting plasma glucose (mg/dL) × fasting triglycerides (mg/dL)/2] × BMI., Results: During the average follow-up period of 3.1 (0.95) years, 1888 men (1.61 %) and 793 women (0.68 %) were newly diagnosed with diabetes. Multivariate Cox regression analysis showed that TyG-BMI was an independent predictor of new-onset diabetes (HR 1.50 per SD increase, 95 %CI: 1.40 to 1.60, P-trend < 0.00001), and the best TyG-BMI cutoff value for predicting new-onset diabetes was 213.2966 (area under the curve 0.7741, sensitivity 72.51 %, specificity 69.54 %). Additionally, the results of subgroup analysis suggested that the risk of TyG-BMI-related diabetes in young and middle-aged people was significantly higher than that in middle-aged and elderly people, and the risk of TyG-BMI-related diabetes in non-obese people was significantly higher than that in overweight and obese people (P for interaction < 0.05)., Conclusions: This cohort study of the Chinese population shows that after excluding other confounding factors, there is a causal association of TyG-BMI with diabetes, and this independent association is more obvious in young, middle-aged and non-obese people., (© 2021. The Author(s).)