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Researchers at Chongqing Medical University in China have conducted a study on the relationship between N6-methyladenosine (m6A) modifications and oral squamous cell carcinoma (OSCC). They used Methylated RNA immunoprecipitation sequencing (MeRIP-seq) to compare OSCC and adjacent normal tissues and identified 2,348 different m6A peaks in the OSCC group. The study found that differentially methylated m6A binding sites were enriched in the coding sequence near the stop codon of both groups. Genes with upregulated m6A-modified sites were associated with the forkhead box O (FOXO) signaling pathway, while genes with downregulated m6A-modified sites were correlated with the PI3K/Akt signaling pathway, spliceosome, protein processing in the endoplasmic reticulum, and endocytosis. The study provides insights into the potential links between OSCC and N6-methyladenosine modification. [Extracted from the article]