Search

Your search keyword '"Khademhosseini, Ali"' showing total 3 results
3 results on '"Khademhosseini, Ali"'

1. Adenosine-associated delivery systems

Author

Kazemzadeh-Narbat, Mehdi, Annabi, Nasim, Tamayol, Ali, Oklu, Rahmi, Ghanem, Amyl, and Khademhosseini, Ali

Subjects
Biotechnology, Bioengineering, Neurosciences, Adenosine, Animals, Drug Delivery Systems, Drug Design, Half-Life, Humans, Polymers, controlled drug delivery, controlled release, drug delivery, drug targeting, nanoparticles, targeted drug delivery, Pharmacology and Pharmaceutical Sciences, Pharmacology & Pharmacy
Abstract

Adenosine is a naturally occurring purine nucleoside in every cell. Many critical treatments such as modulating irregular heartbeat (arrhythmias), regulation of central nervous system (CNS) activity and inhibiting seizural episodes can be carried out using adenosine. Despite the significant potential therapeutic impact of adenosine and its derivatives, the severe side effects caused by their systemic administration have significantly limited their clinical use. In addition, due to adenosine's extremely short half-life in human blood (

Published
2015

2. The Multifaceted Uses and Therapeutic Advantages of Nanoparticles for Atherosclerosis Research.

Author

DiStasio, Nicholas, Lehoux, Stephanie, Khademhosseini, Ali, and Tabrizian, Maryam

Subjects
NANOPARTICLES, ATHEROSCLEROSIS, ATHEROSCLEROTIC plaque, ARTERIOSCLEROSIS, COMPUTED tomography
Abstract

Nanoparticles are uniquely suited for the study and development of potential therapies against atherosclerosis by virtue of their size, fine-tunable properties, and ability to incorporate therapies and/or imaging modalities. Furthermore, nanoparticles can be specifically targeted to the atherosclerotic plaque, evading off-target effects and/or associated cytotoxicity. There has been a wealth of knowledge available concerning the use of nanotechnologies in cardiovascular disease and atherosclerosis, in particular in animal models, but with a major focus on imaging agents. In fact, roughly 60% of articles from an initial search for this review included examples of imaging applications of nanoparticles. Thus, this review focuses on experimental therapy interventions applied to and observed in animal models. Particular emphasis is placed on how nanoparticle materials and properties allow researchers to learn a great deal about atherosclerosis. The objective of this review was to provide an update for nanoparticle use in imaging and drug delivery studies and to illustrate how nanoparticles can be used for sensing and modelling, for studying fundamental biological mechanisms, and for the delivery of biotherapeutics such as proteins, peptides, nucleic acids, and even cells all with the goal of attenuating atherosclerosis. Furthermore, the various atherosclerosis processes targeted mainly for imaging studies have been summarized in the hopes of inspiring new and exciting targeted therapeutic and/or imaging strategies. [ABSTRACT FROM AUTHOR]

Published
2018
Full Text
View/download PDF

3. Diverse applications of nanomedicine

Author

Philipp Jungebluth, Ali Khademhosseini, Xian-En Zhang, Yuzhou Wu, Tai Hyun Park, Christian Dullin, Helmuth Möhwald, Neus Feliu, Mahmoud Soliman, Michael D. George, Nicholas A. Kotov, Buddhisha Udugama, Paul Mulvaney, Ramon A. Alvarez-Puebla, Warren C. W. Chan, Kazunori Kataoka, Sumaira Ashraf, Beatriz Pelaz, Xingyu Jiang, Yury Gogotsi, Naomi J. Halas, Yuliang Zhao, Arnold Grünweller, Laura Ballerini, Jose Oliveira, Ben Zhong Tang, Sebastian Sjöqvist, Susanna Bosi, Andre G. Skirtach, Anne M. Andrews, Teruo Okano, Daxiang Cui, Shuming Nie, Maurizio Prato, Qian Zhang, Patrick Hunziker, Alberto Escudero, Xin Zhou, Qiang Zhang, Huan Meng, Claus-Michael Lehr, Christoph Alexiou, Youqing Shen, Wolfgang J. Parak, Luis M. Liz-Marzán, Lajos P. Balogh, Ji Jian, Andre E. Nel, Molly M. Stevens, Xiaowei Ma, Paul S. Weiss, Zhao Yue, Rainer Tietze, Xiaodong Chen, Raymond E. Schaak, Zhongwei Gu, Chunying Chen, Hsing-Wen Sung, Jindřich Kopeček, Xing-Jie Liang, Alessandra Bestetti, Lily Yang, Harald F. Krug, Paolo Macchiarini, Mei Ling Lim, Vincent M. Rotello, Mónica Carril, Tanja Weil, Zhen Cheng, Pranav Kadhiresan, J. Scott VanEpps, Roland K. Hartmann, Mark C. Hersam, Xiaoyuan Chen, Itamar Willner, Mingyuan Gao, Dong Soo Lee, Amila Samarakoon, Peter Nordlander, Norbert Hampp, Víctor F. Puntes, Cornelia Brendel, Reginald M. Penner, Kam W. Leong, Jianzhong Du, Frauke Alves, Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS),Saarland 9 University, 66123 Saarbrücken, Germany., Pelaz, Beatriz, Alexiou, Christoph, Alvarez Puebla, Ramon A., Alves, Frauke, Andrews, Anne M., Ashraf, Sumaira, Balogh, Lajos P., Ballerini, Laura, Bestetti, Alessandra, Brendel, Cornelia, Bosi, Susanna, Carril, Monica, Chan, Warren C. W., Chen, Chunying, Chen, Xiaodong, Chen, Xiaoyuan, Cheng, Zhen, Cui, Daxiang, Du, Jianzhong, Dullin, Christian, Escudero, Alberto, Feliu, Neu, Gao, Mingyuan, George, Michael, Gogotsi, Yury, Grünweller, Arnold, Gu, Zhongwei, Halas, Naomi J., Hampp, Norbert, Hartmann, Roland K., Hersam, Mark C., Hunziker, Patrick, Jian, Ji, Jiang, Xingyu, Jungebluth, Philipp, Kadhiresan, Pranav, Kataoka, Kazunori, Khademhosseini, Ali, Kopeček, Jindřich, Kotov, Nicholas A., Krug, Harald F., Lee, Dong Soo, Lehr, Claus Michael, Leong, Kam W., Liang, Xing Jie, Ling Lim, Mei, Liz Marzán, Luis M., Ma, Xiaowei, Macchiarini, Paolo, Meng, Huan, Möhwald, Helmuth, Mulvaney, Paul, Nel, Andre E., Nie, Shuming, Nordlander, Peter, Okano, Teruo, Oliveira, Jose, Park, Tai Hyun, Penner, Reginald M., Prato, Maurizio, Puntes, Victor, Rotello, Vincent M., Samarakoon, Amila, Schaak, Raymond E., Shen, Youqing, Sjöqvist, Sebastian, Skirtach, Andre G., Soliman, Mahmoud G., Stevens, Molly M., Sung, Hsing Wen, Tang, Ben Zhong, Tietze, Rainer, Udugama, Buddhisha N., Vanepps, J. Scott, Weil, Tanja, Weiss, Paul S., Willner, Itamar, Wu, Yuzhou, Yang, Lily, Yue, Zhao, Zhang, Qian, Zhang, Qiang, Zhang, Xian En, Zhao, Yuliang, Zhou, Xin, Parak, Wolfgang J., German Academic Exchange Service, Chinese Academy of Sciences, National Natural Science Foundation of China, National Basic Research Program (China), European Commission, Ministerio de Economía y Competitividad (España), Generalitat de Catalunya, Swiss National Science Foundation, Julian Schwinger Foundation, Claude Leon Foundation, National Science Foundation (US), Canadian Institutes of Health Research, Natural Sciences and Engineering Research Council of Canada, Alexander von Humboldt Foundation, Lars Hierta Memorial Foundation, Eusko Jaurlaritza, Research Grants Council (Hong Kong), National Cancer Institute (US), Junta de Andalucía, Research Foundation - Flanders, and German Research Foundation

Subjects
Technology, Chemistry, Multidisciplinary, neurons, General Physics and Astronomy, 02 engineering and technology, Settore BIO/09 - Fisiologia, 01 natural sciences, Engineering (all), Drug Delivery Systems, Imaging tools, Neoplasms, Medicine and Health Sciences, Nanotechnology, General Materials Science, Diverse applications, nanomaterials, Wearable technology, Drug Carriers, Chemistry, Physical, General Engineering, 021001 nanoscience & nanotechnology, Wearable devices, 3. Good health, Chemistry, Nanomedicine, Physical Sciences, QUANTUM-DOT BARCODES, Science & Technology - Other Topics, Medicine, Materials Science (all), 0210 nano-technology, Nano Focus, Materials science, Materials Science, Physics and Astronomy (all), Materials Science, Multidisciplinary, 010402 general chemistry, MESENCHYMAL STEM-CELLS, Vaccine development, TARGETED DRUG-DELIVERY, LABEL-FREE DETECTION, MESOPOROUS SILICA NANOPARTICLES, High throughput screening, MD Multidisciplinary, Animals, Humans, SURFACE-PLASMON RESONANCE, Nanoscience & Nanotechnology, Particle Size, cell physiology, FIELD-EFFECT TRANSISTOR, Biomedicine, Science & Technology, carbon nanotubes, business.industry, COATED GOLD NANOPARTICLES, neurology, IRON-OXIDE NANOPARTICLES, Biology and Life Sciences, Data science, nanomedicine, neurology, nanomaterials, carbon nanotubes, cell physiology, neurons, 0104 chemical sciences, Physics and Astronomy, Targeted drug delivery, Nanoscale size, Nanoparticles, ENHANCED RAMAN-SCATTERING, Drug Delivery, business
Abstract

The design and use of materials in the nanoscale size range for addressing medical and health-related issues continues to receive increasing interest. Research in nanomedicine spans a multitude of areas, including drug delivery, vaccine development, antibacterial, diagnosis and imaging tools, wearable devices, implants, high-throughput screening platforms, etc. using biological, nonbiological, biomimetic, or hybrid materials. Many of these developments are starting to be translated into viable clinical products. Here, we provide an overview of recent developments in nanomedicine and highlight the current challenges and upcoming opportunities for the field and translation to the clinic., This work was supported by the Deutscher Akademischer Austauschdienst (DAAD to Philipps Universität Marburg and Zhejiang University, Hangzhou), the Chinesisch Deutsches Zentrum für Wissenschaftsförderung (“CDZ” to Z.G. and W.J.P.), and the Chinese Academy of Science (CAS). Part of this work was supported by the National Natural Science Foundation (51390481, 81227902, 81625011), National Basic Research Program (2014CB931900) of China (to Y.S.), by the European Commission grant Futurenanoneeds (to V.P. and W.J.P.), by the Spanish Ministerio de Economia y Competitividad (CTQ2011-23167 and CTQ2014-59808R to R.A.A.P.), the Generalitat of Catalunya (2014-SGR-612 to R.A.A.P.), the Deutsche Forschungsgemeinschaft (DFG) (AL552/8-1 to R.T.), the Swiss National Science Foundation (NRP62 to P.H.), the Claude & Julianna Foundation (grant to P.H.), the National Science Foundation (NSF) grants CHE-1306928 (to R.P.) and ECS-0601345; CBET 0933384; CBET 0932823; and CBET 1036672 (to N.A.K.), Canadian Institute of Health Research (grant to W.C.W.C.), and Natural Sciences and Engineering Research Council of Canada (grant to W.C.W.C.). S.A. and B.P. acknowledge a fellowship from the Alexander von Humboldt Foundation. N.F. acknowledges the Lars Hiertas Minne Foundation. M.C. acknowledges Ikerbasque for a Research Fellow position. X.C. acknowledges the Intramural Research Program (IRP), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH). B.Z.T. acknowledges the Innovation and Technology Commission of Hong Kong (ITC-CNERC14SC01). The Pancreatic Cancer research of A.E.N. and H.M. was funded by the U.S. National Cancer Institute, NIH grant # U01CA198846. A.E. acknowledges Junta de Andalucía (Spain) for a Talentia Postdoc Fellowship, co-financed by the European Union's Seventh Framework Programme, grant agreement no 267226. A.G.S. acknowledges support by BOF (UGent) and FWO (Research Foundation Flanders). Part of this work was supported by the National Natural Science Foundation of China.

Published
2017

Catalog

Books, media, physical & digital resources
See catalog results