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Purpose. As a scientific field, bioinformatics has drawn remarkable attention from various fields, such as information technology, mathematics, and modern biological sciences, in recent years. The topic models originating from the field of natural language processing have become the focus of attention with the rapid accumulation of biological datasets. Thus, this research is aimed at modeling the topic content of the bioinformatics literature presented by Iranian researchers in the Scopus Citation Database. Methodology. This research was a descriptive-exploratory study, and the studied population included 3899 papers indexed in the Scopus database, which had been indexed in this database until March 9, 2022. The topic modeling was then performed on the abstracts and titles of the papers. A combination of LDA and TF-IDF was utilized for topic modeling. Findings. The data analysis with topic modeling resulted in identifying seven main topics "Molecular Modeling," "Gene Expression," "Biomarker," "Coronavirus," "Immunoinformatics," "Cancer Bioinformatics," and "Systems Biology." Moreover, "Systems Biology" and "Coronavirus" had the largest and smallest clusters, respectively. Conclusion. The present investigation demonstrated an acceptable performance for the LDA algorithm in classifying the topics included in this field. The extracted topic clusters indicated excellent consistency and topic connection with each other. [ABSTRACT FROM AUTHOR]

Planning and scheduling of operating rooms (ORs) is important for hospitals to improve efficiency and achieve high quality of service. Due to significant uncertainty in surgery durations, scheduling of ORs can be very challenging. In this paper, surgical case scheduling problem with uncertain duration of surgeries in multi resource environment is investigated. We present a two-stage stochastic mixed-integer programming model, named SOS, with the objective of total ORs idle time and overtime. Also, in this paper a two-step approach is proposed for solving the model based on the L-shaped algorithm. Proposing the model in a multi resources environment with considering real-life limitations in academic hospitals and developing an approach for solving this stochastic model efficiently form the main contributions of this paper. The model is evaluated through several numerical experiments based on real data from Hasheminejad Kidney Center (HKC) in Iran. The solutions of SOS are compared with the deterministic solutions in several real instances. Numerical results show that SOS enjoys a better performance in 97% of the cases. Furthermore, the results of comparing with actual schedules applied in HKC reveal a notable reduction of OR idle time and over time which illustrate the efficiency of the proposed model in practice. [ABSTRACT FROM AUTHOR]

Improving network power quality through harmonic reduction requires recognition of Harmonic Sources (HSs) to drive them to compensate their harmonics. This paper proposes a new method for equitable distribution of the Harmonic Compensation Cost of the network among the HSs based on the Harmonic Contribution Matrix. Each element of the Harmonic Contribution Matrix is the harmonic contribution of a specific source to the harmonic voltage of a specific bus. The output of the proposed method is a penalty curve for each HS over time. The amount of the fine estimated for each individual HS per hour is a function of not only the contribution of that HS to the harmonic voltage of different buses, but also the contribution of the Harmonic Compensation Cost from the perspective of each bus, nominal voltage of each bus, and the sensitivity of each bus to the harmonic voltage. The proposed algorithm is evaluated on the IEEE 14‐bus network and Esfahan regional electrical power network in Iran. The simulation results demonstrate the capability of the proposed method to allocate the hourly penalty curve to the HSs. [ABSTRACT FROM AUTHOR]

This paper considers a real case problem of supply chain network design inspired from a wheat distribution network in Iran. It generates a network with capacity acquisition and fleet management. The problem first is formulated as a mixed integer linear programming model. Then, a logic-based Benders decomposition algorithm is appropriately developed as the solution methodology. In the presented algorithm, the problem is decomposed into two models of master and subproblem. The master problem is improved by means of the preprocessing and valid inequalities. Moreover, three Benders cuts, one optimality and two feasibility cuts, are developed for the algorithm. The general and relative performance of the model and algorithm is experimentally evaluated. The wheat distribution system of Iran is considered here as the case study of this research. The model is developed based on Iran's wheat distribution system. All the results show that the algorithm significantly outperforms the mathematical model of the case study. For example, the algorithm solves 95% of the tested instances to optimality, yet the model solves 29%. [ABSTRACT FROM AUTHOR]

This paper presents a nature-based algorithm, titled multivariable teaching-learning-based optimization (MTLBO) algorithm. MTLBO algorithm during an iterative process can estimates the best values of the buried structure (model) parameters in a multi-objective problem. The algorithm works in two computa-tional phases: the teacher phase and the learner phase. The major purpose of the MTLBO algorithm is to modify the value of the learners and thus, improving the value of the model parameters which leads to the optimal solution. The variables of each learner (model) are the depth (z), amplitude coefficient (k), shape factor (q), angle of effective magnetization (Î,) and axis location (x0) parameters. We employ MTLBO method for the magnetic anomalies caused by the buried structures with a simple geometric shape such as sphere and horizontal cylinder. The efficiency of the MTLBO is also studied by noise corruption synthetic data, as the acceptable results were obtained. We have applied the MTLBO for the interpretation of the four magnetic anomaly profiles from Iran, Brazil and India. [ABSTRACT FROM AUTHOR]

The special features of some old residential complexes make reconstructing a better option than rebuilding. The complexity of redesign issues, the ability of computers to solve problems, and the capability of evolutionary optimization techniques in architecture make the use of these methods a priority over traditional processes. This paper, while introducing Particle Swarm Optimization (PSO) as one of the swarm intelligence based algorithms, answers the question of how this algorithm can be used to redesign residential complexes. To achieve this, after reviewing the application of PSO algorithms in architectural space planning, the redesign criteria and constraints was divided into four categories; including primary design specifications, contact-related criteria, designer-related criteria and redesign-related constraints. After the quantification process of these criteria, how to implement the algorithm to achieve optimal plans for each of the five plan types available in high-rise apartment complex in Mashhad, Iran, was shown as a case study. [ABSTRACT FROM AUTHOR]

Abstract: Natural language processing is a composition of several error‐prone and challenging tasks, including part of speech tagging, word sense disambiguation, named entity recognition, and compound verb detection. Studying intrasentence relations and roles is essential to improve the mentioned subtasks. Semi‐automatic schemes such as ontologies can be applied to clarify word's dependencies. This paper presents an ontology that is targeting to improve POS tagging, WSD, NER, and compound verb detection in Persian with extra properties that may ameliorate machine translation. The ontology is tested in combinations with several state‐of‐art algorithms on Dadegan corpus. The results show that coping semantic analysis with machine learning methods enhance relation detection and consequently precision of the mentioned subtasks, which is not widely addressed in Persian. Furthermore, the experimental results declare that the accuracy rate increases between 4.5 and 23% for different tasks. [ABSTRACT FROM AUTHOR]

Hub location problem is further used in transportation and telecommunication networks (airlines, post delivery services, etc.) so origin-destination pairs, receive or send commodities via special facilities called Hub. Hub median problem with multiple allocation is an NP-hard problem which includes both locating hub facilities and allocating non-hub nodes to hubs as minimizes total transportation and location costs. In this paper, the hub median problem is considered in an environment which network flow varies during the time periods and the capacities of hubs and arcs are unlimited. Also opening and closing hubs in different periods of planning horizon are permitted. The model and the proposed algorithm for this problem were considered to Iran airlines network using real passenger flows data. Computational results state that the dynamic network compared with static model has lower cost and whatever the number of time periods in dynamic case increases, the cost will be reduced as well. [ABSTRACT FROM AUTHOR]

Abstract: The algorithms used in Arabic and medieval European mathematics for extracting cube roots are studied with respect to algebraic structure and use of external memory (dust board, table, paper). They can be separated into two distinct groups. One contains methods used in the eastern regions from the 11th century, closely connected to Chinese techniques, and very uniform in structure. The other group, showing much wider variation, contains early Indian methods and techniques developed in central and western parts of the Arabic areas and in Europe. This study supports hypotheses previously formulated by Luckey and Chemla on an early scientific connection between China and Persia. [Copyright &y& Elsevier]

Background: Hepatitis B virus (HBV) infection is an important health problem worldwide with critical outcomes. The nucleoside analog lamivudine (LMV) is a potent inhibitor of HBV polymer­ase and impedes HBV replication in patients with chronic hepatitis B. Treatment with LMV for long periods causes the appearance and reproduction of drug-resistant strains, rising to more than 40% after 2 years and to over 50% and 70% after 3 and 4 years, respectively.Objectives: Artificial neural networks (ANNs) were used to make predictions with regard to re­sistance phenotypes using biochemical and biophysical features of the YMDD sequence.Patients and Methods: The study population comprised patients who were intended for surgery in various hospitals in Tehran-Iran. An ACRS-PCR method was performed to distinguish muta­tions in the YMDD motif of HBV polymerase. In the training and testing stages, these parameters were used to identify the most promising optimal network. The ideal values of RMSE and MAE are zero, and a value near zero indicates better performance. The selection was performed using statistical accuracy measures, such as root mean square error (RMSE), coefficient of determina­tion (R2), and mean absolute error (MAE). The main purpose of this paper was to develop a new method based on ANNs to simulate HBV drug resistance using the physiochemical properties of the YMDD motif and compare its results with multiple regression models. Results: The results of the MLP in the training stage were 0.8834, 0.07, and 0.09 and 0.8465, 0.160.04 in the testing stage; for the total data, the values were 0.8549, 0.115, and 0.065, respec­tively. The MLP model predicts lamivudine resistance in HBV better than the MLR model. Conclusions: The ANN model can be used as an alternative method of predicting the outcome of HBV therapy. In a case study, the proposed model showed vigorous clusterization of predicted and observed drug responses. The current study was designed to develop an algorithm for pre­dicting drug resistance using chemiophysical data with artificially created neural networks. To this end, an intelligent and multidisciplinary program should be developed on the basis of the information to be gained on the essentials of different applications by similar investigations. This program will help design expert neural network architectures for each application auto­matically. [ABSTRACT FROM AUTHOR]

Land surface temperature (LST) is a significant parameter for many applications. Many studies have proposed various algorithms, such as the split-window method, for retrieving surface temperatures from two spectrally adjacent thermal infrared bands of satellite data. Each algorithm is developed for a limited study area and application. In this paper, as part of developing an optimal split-window method in the southeast of Tehran province, Iran, four commonly applied algorithms to retrieve the LST from AVHRR were compared. This study was carried out in a wheat farm site located in the Pakdasht Agricultural Region. Measurements of LST over the farm were made with a manual infrared radiometer at the time of NOAA overpass for 18 days of May to June 2004. These days were cloud free over the study area. A total of 18 NOAA images were acquired for the days that LST measurements were made. The temperatures derived by the different split-window algorithms were compared to ground truth measurements. The performance of the split window algorithms was checked with three statistical indices: root mean square error (RMSE), mean bias error (MBE) and coefficient of determination (R2). The results showed that the Ulivieri split-window algorithm produced the lowest value of RMSE and MBE (2.71 and 0.26 K, respectively) and its highest value of R2 (0.92) gave more accurate results than the other algorithms. [ABSTRACT FROM AUTHOR]

In this paper optimal and cost-effective design of a photovoltaic/wind turbine/fuel cell (PV/WT/FC), the renewable energy system is proposed with the objective of lifespan cost of hybrid system (LSCS) minimisation and considering reliability constraint as a maximum of load interruption probability (LIP) as LIPmax to supply the demand of residential-commercial centres (RCC) located in Iran based on real data of irradiance and wind speed of this region. A new hybrid meta-heuristic algorithm named hybrid grey wolf optimiser-sine cosine algorithm (HGWOSCA) based on the exponential decreasing function (EDF) with high accuracy and speed of optimisation in achieving to the global solution is applied to determine the optimal size of system components. The superiority of the proposed HGWOSCA is compared with SCA, GWO and particle swarm optimisation (PSO) methods in designing of different combinations of the hybrid system and under varying reliability constraint. The results showed that the PV/WT/FC combination is the best combination in view of LSCS and LIPmax for supplying the RCC as a cost-effective and reliable combination. The superiority of the HGWOSCA in designing different combinations of the hybrid system is proved with fewer LSCS and LIP than the other methods with more convergence speed and accuracy. The results clearly showed that the use of hydrogen storage as a reserve power has well compensated the fluctuations in renewable sources production for meeting the RCC load to achieve optimal reliability. The results cleared that the cost of per kW of RCC supply for LIPmax = 1% and LIPmax = 5% is 0.853 and 0.764 $. The results indicated that increasing the failure rate of the components increases the system cost and weakens the reliability. In addition, the results showed that increased FC efficiency has reduced the level of reserve hydrogen, reduced the LSCS, and improved reliability. [ABSTRACT FROM AUTHOR]

The optimal allocation and sizing of distributed generation (DG) resources are important in installing these resources, to improve the technical parameters of the network, including the power losses, voltage profile, and short-circuit level, as well as to increase economic factors. In this paper, a new multi-criteria algorithm and objective function are proposed for the optimal sizing and allocation of renewable and non-renewable DG resources simultaneously. The proposed algorithm is implemented on 63/20 kV substations at 20 kV levels. In the proposed objective function, all important technical and economic factors as well as important constraints, such as penetration level of DGs and budget constraint, are considered in a way that all factors are assigned to monetary values. Moreover, a new mathematical formulation is introduced for the allocation of renewable DG resources to reduce run-time optimization. The genetic algorithm (GA) is employed in the proposed algorithm to minimize the objective function. For renewable DG resources, photovoltaic panels and wind turbines, and for non-renewable DG resources, gas turbines are considered. The 115 buses network of Bakhtar Regional Electric Company (BREC) in Iran is used to evaluate the performance of the proposed algorithm. The results demonstrate that the proposed algorithm improves technical factors efficiently and maximizes the profitability of the investment. [ABSTRACT FROM AUTHOR]