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16 results on '"van den Berg, Victor J."'

1. Potential role of left atrial strain in estimation of left atrial pressure in patients with chronic heart failure

Author

Aga, Yaar S., primary, Abou Kamar, Sabrina, additional, Chin, Jie Fen, additional, van den Berg, Victor. J., additional, Strachinaru, Mihai, additional, Bowen, Daniel, additional, Frowijn, Rene, additional, Akkerhuis, Martijn K., additional, Constantinescu, Alina A., additional, Umans, Victor, additional, Geleijnse, Marcel L., additional, Boersma, Eric, additional, Brugts, Jasper J., additional, Kardys, Isabella, additional, and van Dalen, Bas M., additional

Published
2023
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2. Prognostic value of temporal patterns of global longitudinal strain in patients with chronic heart failure

Author

Abou Kamar, Sabrina, primary, Aga, Yaar S., additional, de Bakker, Marie, additional, van den Berg, Victor J., additional, Strachinaru, Mihai, additional, Bowen, Dan, additional, Frowijn, René, additional, Akkerhuis, K. Martijn, additional, Brugts, Jasper, additional, Manintveld, Olivier, additional, Umans, Victor, additional, Geleijnse, Marcel L., additional, Boersma, Eric, additional, van Dalen, Bas M., additional, and Kardys, Isabella, additional

Published
2023
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3. Persistently elevated levels of sST2 after acute coronary syndrome are associated with recurrent cardiac events

Author

van den Berg, Victor. J., Vroegindewey, Maxime M., Umans, Victor A., van der Harst, Pim, Asselbergs, Folkert W., Akkerhuis, K. Martijn, Kardys, Isabella, Boersma, Eric, Cardiovascular Centre (CVC), and Cardiology

Subjects
Male, sST2, RISK, NT-PROBNP, Health, Toxicology and Mutagenesis, Clinical Biochemistry, Middle Aged, Prognosis, Interleukin-1 Receptor-Like 1 Protein, Biochemistry, C-REACTIVE PROTEIN, acute coronary syndrome, SDG 3 - Good Health and Well-being, MYOCARDIAL-INFARCTION, MANAGEMENT, IL-33, Humans, atherosclerosis, repeated measurements, SOLUBLE ST2, Biomarkers, secondary prevention, Proportional Hazards Models
Abstract

Purpose: Higher soluble ST2 (sST2) levels at admission are associated with adverse outcome in acute coronary syndrome (ACS) patients. We studied the dynamics of sST2 over time in post-ACS patients prior to a recurrent ACS or cardiac death. Methods: We used the BIOMArCS case cohort, consisting of 187 patients who underwent serial blood sampling during one-year follow-up post-ACS. sST2 was batch-wise quantified after completion of follow-up in a median of 8 (IQR: 5–11) samples per patient. Joint modelling was used to investigate the association between longitudinally measured sST2 and the endpoint, adjusted for gender, GRACE risk score and history of cardiovascular diseases. Results: Median age was 64 years and 79% were men. The 36 endpoint patients had systematically higher sST2 levels than those that remained endpoint free (mean value 29.6 ng/ml versus 33.7 ng/ml, p-value 0.052). The adjusted hazard ratio for the endpoint per standard deviation increase of sST2 was 1.64 (95% confidence interval: 1.09–2.34; p = 0.019) at any time point. We could not identify a steady or sudden increase of sST2 in the run-up to the combined endpoint. Conclusion: Asymptomatic post-ACS patients with persistently higher sST2 levels are at higher risk of recurrent ACS or cardiac death during one-year follow-up.

Published
2022

4. IGF-1 is not related to long-term outcome in hyperglycemic acute coronary syndrome patients

Author

Iswandi, Cindya P, primary, van den Berg, Victor J, additional, Simsek, Suat, additional, Velzen, Daan van, additional, Boekel, Edwin Ten, additional, Cornel, Jan-Hein, additional, Boer, Sanneke de, additional, Mulder, Maarten de, additional, Akkerhuis, K Martijn, additional, Boersma, Eric, additional, Umans, Victor A, additional, and Kardys, Isabella, additional

Published
2021
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5. Temporal Evolution of Serum Concentrations of High‐Sensitivity Cardiac Troponin During 1 Year After Acute Coronary Syndrome Admission

Author

van den Berg, Victor J., primary, Oemrawsingh, Rohit M., additional, Umans, Victor A. W. M., additional, Kardys, Isabella, additional, Asselbergs, Folkert W., additional, van der Harst, Pim, additional, Hoefer, Imo E., additional, Kietselaer, Bas, additional, Lenderink, Timo, additional, Oude Ophuis, Anton J., additional, van Schaik, Ron H., additional, de Winter, Robbert J., additional, Akkerhuis, K. Martijn, additional, Boersma, Eric, additional, Mulder, Maarten, additional, Schotborgh, Carl, additional, Ronner, Eelko, additional, Liem, Anho, additional, Haitsma, David, additional, Maas, Arthur, additional, Ilmer,, Ben, additional, Dijkgraaf, Rene, additional, Kie, S. Hong, additional, Wardeh, Alexander J, additional, Hermans, Walther, additional, Cramer, Etienne, additional, Doevendans, Pieter A, additional, and Simoons, Maarten L, additional

Published
2021
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6. TEMPORARY REMOVAL: IgM anti-malondialdehyde low density lipoprotein antibody levels indicate coronary heart disease and necrotic core characteristics in the Nordic Diltiazem (NORDIL) study and the Integrated Imaging and Biomarker Study 3 (IBIS-3)

Author

van den Berg, Victor J., Haskard, Dorian O., Fedorowski, Artur, Hartley, Adam, Kardys, Isabella, Caga-Anan, Mikhail, Martijn Akkerhuis, K., Oemrawsingh, Rohit M., van Geuns, Robert Jan, de Jaegere, Peter, van Mieghem, Nicolas, Regar, Evelyn, Ligthart, Jurgen M.R., Umans, Victor A.W.M., Serruys, Patrick W., Melander, Olle, Boersma, Eric, and Khamis, Ramzi Y.

Subjects
Male, Research paper, Coronary Artery Disease, Middle Aged, Atherosclerosis, Lipoproteins, LDL, Necrosis, Immunoglobulin M, Malondialdehyde, Humans, Female, Prospective Studies, Biomarkers, Aged
Abstract

Certain immunoglobulins (Ig) are proposed to have protective functions in atherosclerosis.We tested whether serum levels of IgG and IgM autoantibodies against malondialdehyde low density lipoprotein (MDA-LDL) are associated with clinical coronary heart disease (CHD) and unfavorable plaque characteristics.NORDIL was a prospective study investigating adverse cardiovascular outcomes in hypertensive patients. IBIS-3 analyzed lesions in a non-culprit coronary artery with50% stenosis using radiofrequency intravascular ultrasound (RF-IVUS) and near-infrared spectroscopy (NIRS). Imaging was repeated after a median of 386?days on rosuvastatin. Associations of antibodies with incident CHD and imaging parameters were assessed in the two sub-studies respectively.From 10,881 NORDIL patients, 87 had serum sampled at baseline and developed CHD over 4.5 years, matched to 227 controls. Higher titers of IgM anti-MDA-LDL had a protective effect on adverse outcomes, with odds ratio 0.29 (0.11, 0.76; p=0.012; p=0.016 for trend). Therefore, the effect was explored at the lesional level in IBIS-3. 143 patients had blood samples and RF-IVUS measurements available, and NIRS was performed in 90 of these. At baseline, IgM anti-MDA-LDL levels had a strong independent inverse relationship with lesional necrotic core volume (p=0.027) and percentage of plaque occupied by necrotic core (p=0.011), as well as lipid core burden index (p=0.024) in the worst 4 mm segment.Our study supports the hypothesis that lower circulating levels of IgM anti-MDA-LDL are associated with clinical CHD development, and for the first time relates these findings to atherosclerotic plaque characteristics that are linked to vulnerability.

Published
2018

7. Circulating Biomarkers of Cell Adhesion Predict Clinical Outcome in Patients with Chronic Heart Failure

Author

Bouwens, Elke, primary, van den Berg, Victor J., additional, Akkerhuis, K. Martijn, additional, Baart, Sara J., additional, Caliskan, Kadir, additional, Brugts, Jasper J., additional, Mouthaan, Henk, additional, van Ramshorst, Jan, additional, Germans, Tjeerd, additional, Umans, Victor A. W. M., additional, Boersma, Eric, additional, and Kardys, Isabella, additional

Published
2020
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8. Details on high frequency blood collection, data analysis, available material and patient characteristics in BIOMArCS

Author

Boersma, Eric, primary, Vroegindewey, Maxime M., additional, van den Berg, Victor J., additional, Asselbergs, Folkert W., additional, van der Harst, Pim, additional, Kietselaer, Bas, additional, Lenderink, Timo, additional, Oude Ophuis, Anton J., additional, Umans, Victor A.W.M., additional, de Winter, Robbert J., additional, Oemrawsingh, Rohit M., additional, and Akkerhuis, K. Martijn, additional

Published
2019
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10. Longitudinal patterns of N-terminal pro B-type natriuretic peptide, troponin T, and C-reactive protein in relation to the dynamics of echocardiographic parameters in heart failure patients

Author

Klimczak-Tomaniak, Dominika, primary, van den Berg, Victor J, additional, Strachinaru, Mihai, additional, Akkerhuis, K Martijn, additional, Baart, Sara, additional, Caliskan, Kadir, additional, Manintveld, Olivier C, additional, Umans, Victor, additional, Geleijnse, Marcel, additional, Boersma, Eric, additional, van Dalen, Bas M, additional, and Kardys, Isabella, additional

Published
2019
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12. IgM anti-malondialdehyde low density lipoprotein antibody levels indicate coronary heart disease and necrotic core characteristics in the Nordic Diltiazem (NORDIL) study and the Integrated Imaging and Biomarker Study 3 (IBIS-3)

Author

van den Berg, Victor J., primary, Haskard, Dorian O., additional, Fedorowski, Artur, additional, Hartley, Adam, additional, Kardys, Isabella, additional, Caga-Anan, Mikhail, additional, Akkerhuis, K. Martijn, additional, Oemrawsingh, Rohit M., additional, van Geuns, Robert Jan, additional, de Jaegere, Peter, additional, van Mieghem, Nicolas, additional, Regar, Evelyn, additional, Ligthart, Jurgen M.R., additional, Umans, Victor A.W.M., additional, Serruys, Patrick W., additional, Melander, Olle, additional, Boersma, Eric, additional, and Khamis, Ramzi Y., additional

Published
2018
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16. Longitudinal patterns of N-terminal pro B-type natriuretic peptide, troponin T, and C-reactive protein in relation to the dynamics of echocardiographic parameters in heart failure patients.

Author

Klimczak-Tomaniak D, van den Berg VJ, Strachinaru M, Akkerhuis KM, Baart S, Caliskan K, Manintveld OC, Umans V, Geleijnse M, Boersma E, van Dalen BM, and Kardys I

Subjects
Biomarkers, C-Reactive Protein, Echocardiography, Humans, Stroke Volume, Ventricular Function, Left, Heart Failure blood, Heart Failure diagnostic imaging, Natriuretic Peptide, Brain blood, Peptide Fragments blood, Troponin T blood
Abstract

Aims: To further elucidate the nature of the association between N-terminal pro-B type natriuretic peptide (NT-proBNP), high-sensitivity cardiac troponin T (hs-TnT), C-reactive protein (CRP), and clinical outcome, we examined the relationship between serial simultaneous measurements of echocardiographic parameters and these biomarkers in chronic heart failure (CHF) patients., Methods and Results: In 117 CHF patients with ejection fraction ≤50%, NT-proBNP, hs-TnT, and CRP were measured simultaneously with echocardiographic evaluation at 6-month intervals until the end of 30 months follow-up or until an adverse clinical event occurred. Linear mixed effects models were used for data-analysis. Median follow-up was 2.2 years (interquartile range 1.5-2.6). We performed up to six follow-up evaluations with 55% of patients having at least three evaluations performed. A model containing all three biomarkers revealed that doubling of NT-proBNP was associated with a decrease in left ventricular ejection fraction by 1.83 (95% confidence interval -2.63 to -1.03)%, P < 0.0001; relative increase in mitral E/e' ratio by 12 (6-18)%, P < 0.0001; relative increase in mitral E/A ratio by 16 (9-23)%, P < 0.0001; decrease in tricuspid annular plane systolic excursion by 0.66 (-1.27 to -0.05) mm, P = 0.03; rise in tricuspid regurgitation peak systolic gradient by 2.74 (1.43-4.05) mmHg, P = 0.001; and increase in left ventricular and atrial dimensions, P < 0.05. Hs-TnT and CRP showed significant associations with some echocardiographic parameters after adjustment for clinical covariates, but after adjustment for the other biomarkers the associations were not significant., Conclusion: Serum NT-proBNP independently reflects changes in echocardiographic parameters of systolic function, left ventricular filling pressures, estimated pulmonary pressure, and chamber dimensions. Our results support further studies on NT-proBNP as a surrogate marker for haemodynamic congestion and herewith support its potential value for therapy guidance., (Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2019. For permissions, please email: journals.permissions@oup.com.)

Published
2020
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