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18 results on '"nuclear targets"'

1. Uranium Carbide Fibers with Nano-Grains as Starting Materials for ISOL Targets

Author

Sanjib Chowdhury, Leonor Maria, Adelaide Cruz, Dario Manara, Olivier Dieste-Blanco, Thierry Stora, and António Pereira Gonçalves

Subjects
nuclear targets, uranium carbides, nano-scale, electrospinning, fibers, Chemistry, QD1-999
Abstract

This paper presents an experimental study about the preparation, by electrospinning, of uranium carbide fibers with nanometric grain size. Viscous solutions of cellulose acetate and uranyl salts (acetate, acetylacetonate, and formate) on acetic acid and 2,4-pentanedione, adjusted to three different polymer concentrations, 10, 12.5, and 15 weight %, were used for electrospinning. Good quality precursor fibers were obtained from solutions with a 15% cellulose acetate concentration, the best ones being produced from the uranyl acetate solution. As-spun precursor fibers were then decomposed by slow heating until 823 K under argon, resulting in a mixture of nano-grained UO2 and C fibers. A last carboreduction was then carried out under vacuum at 2073 K for 2 h. The final material displayed UC2−y as the major phase, with grain sizes in the 4 nm–10 nm range. UO2+x was still present in moderate concentrations (~30 vol.%). This is due to uncomplete carboreduction that can be explained by the fiber morphology, limiting the effective contact between C and UO2 grains.

Published
2020
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2. Promising targets and current clinical trials in metastatic non-squamous NSCLC.

Author

Zer, Alona and Leighl, Natasha

Subjects
CANCER treatment, NON-small-cell lung carcinoma, EPIDERMAL growth factor receptors, ANAPLASTIC lymphoma kinase, ADENOCARCINOMA, ADP-ribosyltransferases, HEAT shock proteins
Abstract

Lung adenocarcinoma is the most common subtype of lung cancer today.With the discovery of epidermal growth factor receptor (EGFR) mutations, anaplastic lymphoma kinase (ALK) rearrangements, and effective targeted therapy, personalized medicine has become a reality for patients with lung adenocarcinoma. Here, we review potential additional targets and novel therapies of interest in lung adenocarcinoma including targets within the cell surface (receptor tyrosine kinases EGFR, human epidermal growth factor receptor 2, RET, ROS1, mesenchymal-epidermal transition, TRK), targets in intracellular signal transduction (ALK, RAS-RAF-MEK, PI3K-AKT-PTEN, WNT), nuclear targets such as poly-ADP ribose polymerase, heat shock protein 90, and histone deacetylase, and selected pathways in the tumor environment. With the evolving ability to identify specific molecular aberrations in patient tumors in routine practice, our ability to further personalize therapy in lung adenocarcinoma is rapidly expanding. [ABSTRACT FROM AUTHOR]

Published
2014
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3. Uranium Carbide Fibers with Nano-Grains as Starting Materials for ISOL Targets.

Author

Chowdhury, Sanjib, Maria, Leonor, Cruz, Adelaide, Manara, Dario, Dieste-Blanco, Olivier, Stora, Thierry, and Gonçalves, António Pereira

Subjects
*CELLULOSE acetate, *URANIUM, *FIBERS, *CARBIDES, *ACETIC acid, *GRAIN size
Abstract

This paper presents an experimental study about the preparation, by electrospinning, of uranium carbide fibers with nanometric grain size. Viscous solutions of cellulose acetate and uranyl salts (acetate, acetylacetonate, and formate) on acetic acid and 2,4-pentanedione, adjusted to three different polymer concentrations, 10, 12.5, and 15 weight %, were used for electrospinning. Good quality precursor fibers were obtained from solutions with a 15% cellulose acetate concentration, the best ones being produced from the uranyl acetate solution. As-spun precursor fibers were then decomposed by slow heating until 823 K under argon, resulting in a mixture of nano-grained UO2 and C fibers. A last carboreduction was then carried out under vacuum at 2073 K for 2 h. The final material displayed UC2−y as the major phase, with grain sizes in the 4 nm–10 nm range. UO2+x was still present in moderate concentrations (~30 vol.%). This is due to uncomplete carboreduction that can be explained by the fiber morphology, limiting the effective contact between C and UO2 grains. [ABSTRACT FROM AUTHOR]

Published
2020
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4. Systematic uncertainties in long-baseline neutrino-oscillation experiments

Author

Physics, Ankowski, Artur M., Mariani, Camillo, Physics, Ankowski, Artur M., and Mariani, Camillo

Abstract

Future neutrino-oscillation experiments are expected to bring definite answers to the questions of neutrino-mass hierarchy and violation of charge-parity symmetry in the lepton sector. To realize this ambitious program it is necessary to ensure a significant reduction of uncertainties, particularly those related to neutrino-energy reconstruction. In this review, we discuss different sources of systematic uncertainties, paying special attention to those arising from nuclear effects and detector response. By analyzing nuclear effects we show the importance of developing accurate theoretical models, capable to provide quantitative description of neutrino cross sections, together with the relevance of their implementation in Monte Carlo generators and extensive testing against lepton-scattering data. We also point out the fundamental role of efforts aiming to determine detector responses in test-beam exposures.

Published
2017

5. Measurement of the $\nu_{\mu}$ charged current quasi-elastic cross-section on carbon with the T2K on-axis neutrino beam

Author

Y. Nishimura, P. A. Rodrigues, C. A. Miller, E. Rondio, N. McCauley, A. Minamino, Joshua Hignight, Yoshihiro Suzuki, P. de Perio, Yoshikazu Yamada, K. Huang, T. Maruyama, P. Przewlocki, J. Caravaca Rodríguez, H.A. Tanaka, D. Brailsford, O. Drapier, M. Malek, A. Blondel, J. H. Jo, R. Poutissou, C. W. Walter, Anatoly Kopylov, Lester D.R. Thompson, P. Bartet-Friburg, A. Cervera, B. E. Berger, Masashi Tanaka, C. Nantais, V. Palladino, G.D. Barr, M. Kabirnezhad, K. Nishikawa, J. Holeczek, Jan T. Sobczyk, A. P. Furmanski, B. Quilain, M. Yu, T. Ovsyannikova, C. Pistillo, K. Nakayoshi, C. K. Jung, S. Berkman, S. Martynenko, Takaaki Kajita, J. Lagoda, T. Tomura, S. Murphy, J. M. Poutissou, C. Bronner, B. Smith, E. Reinherz-Aronis, R. L. Helmer, R. J. Wilson, A. Redij, Y. Shustrov, V. Paolone, K. Wakamatsu, Hiroyuki Sekiya, A. Jacob, L. Zambelli, I. Karpikov, S. King, B. Still, K. Iyogi, S. Bolognesi, M. R. Vagins, K. Iwamoto, P. Martins, E. Scantamburlo, P. Stamoulis, F. Sato, R. Castillo, Yuichi Oyama, Y. Fukuda, Kendall Mahn, M. Nirkko, R. P. Litchfield, M. Ravonel, A. Rychter, W. R. Kropp, O. V. Mineev, Masato Shiozawa, R.P. Kurjata, P. Rojas, M. Mezzetto, M. Ieva, Akitaka Ariga, Ko Okumura, E. D. Zimmerman, R. Shah, W. Warzycha, Shigeki Aoki, L. Pickard, S. Giffin, S. Assylbekov, Koji Yamamoto, J. P. Lopez, F. Hosomi, Susumu Takahashi, S. Tobayama, A. Zalewska, Federico Sanchez, Y. Takeuchi, I. Z. Danko, M. B. Smy, K. Abe, A. Murakami, Yu. Kudenko, V. Matveev, K. Nakamura, Takahiro Hiraki, M. A.M. Rayner, T. Wongjirad, S. Manly, G. De Rosa, Leïla Haegel, R. A. Owen, A. K. Ichikawa, S. Roth, J. Kameda, S. A. Dytman, K. Sakashita, A. Haesler, R. Tacik, O. Perevozchikov, D. Payne, S. J. Coleman, Antonin Vacheret, V. Galymov, M. Ikeda, S. Bhadra, S. M. Oser, T. Hayashino, C. Hearty, D. R. Hadley, M. M. Khabibullin, E. S. Pinzon Guerra, S. B. Boyd, Th. A. Mueller, A. Garcia, M. Miura, R. Ohta, Stefan Schoppmann, G. Christodoulou, M. Ziembicki, Matthew T. Reeves, M. Barbi, M. Tzanov, P. Mijakowski, J. Zalipska, J. Insler, T. Yuan, T. Sekiguchi, D. Ruterbories, S. Horikawa, C. J. Metelko, T. Ishii, Y. Seiya, T. Wachala, L. Ludovici, André Rubbia, S. Bordoni, C. Touramanis, R. Terri, E. Mazzucato, M. Jiang, S. Moriyama, M. Zito, T. J. Irvine, F. Bay, A. Hillairet, Hiroaki Aihara, H. M. O'Keeffe, S. R. Johnson, Antonio Ereditato, N. Yershov, P. N. Ratoff, Hidekazu Kakuno, M. Sorel, T. Kutter, R. A. Wendell, Masayuki Nakahata, M. McCarthy, A. Thorley, Y. Uchida, C. Riccio, S. L. Cartwright, A. Korzenev, Kevin Scott McFarland, Vincenzo Berardi, Kazuhiro Suzuki, C. Ferchichi, E. Larkin, T. Feusels, A. Longhin, M. Friend, K. Connolly, G. A. Fiorentini, S. Short, H. K. Tanaka, N. C. Hastings, P. Plonski, J. Marteau, Z. Williamson, Teppei Katori, L. L. Kormos, A. Clifton, M. J. Wilking, P. Kitching, K. Mavrokoridis, F. d. M. Blaszczyk, Michal Dziewiecki, M. G. Catanesi, K. Gilje, Alexander Finch, D. Shaw, T. Hasegawa, M. Lawe, Rhiju Das, H. W. Sobel, Y. Kanazawa, A. Konaka, L. Southwell, J. Myslik, Jan Kisiel, T. Dealtry, A. Missert, Artur F. Izmaylov, M. O. Wascko, D. Terhorst, J. D. Perkin, W. H. Toki, B. Jamieson, E. Kearns, T. Tsukamoto, D. Goeldi, T. Kobayashi, S. Di Luise, Yusuke Koshio, M. D. Haigh, L. Cremonesi, K. G. Nakamura, J. Steinmann, T. Golan, I. Lamont, Masashi Yokoyama, F. Di Lodovico, A. T. Suzuki, M. Murdoch, M. Tada, G. Vasseur, E. Poplawska, S. Nakayama, S. Yen, T. Yano, Marco Laveder, Hidetoshi Kubo, Kentaroh Yoshida, A. C. Weber, J. F. Martin, Yuki Fujii, D. Autiero, T. Nakadaira, P. Hamilton, J. Żmuda, K. Zaremba, Seiko Hirota, T. Ishida, T. Kikawa, D. Kielczewska, M. Batkiewicz, Yusuke Suda, L. Magaletti, C. Giganti, M. Gonin, L. Escudero, A. Dabrowska, J. A. Nowak, A. Kolaceke, E. Iwai, Atsushi Takeda, J. Dumarchez, K. E. Duffy, J. Schwehr, C. Yanagisawa, W. Oryszczak, J. Adam, A. Mefodiev, J. Yoo, N. Chikuma, D. Cherdack, J. Imber, R. Sacco, A. N. Khotjantsev, S. Dolan, T. Lindner, S. Emery-Schrenk, Scott Davis, D. Hansen, C. Densham, M. Posiadala-Zezula, N. Grant, J. L. Palomino, G. Collazuol, Mark Scott, Tsuyoshi Nakaya, Gareth J. Barker, M. Hierholzer, Y. Petrov, J. P. Coleman, A. Himmel, A. Kilinski, F. Shaker, B. A. Popov, R. G. Calland, D. Gudin, M. Lazos, N. J. Buchanan, Y. Totsuka, T. Okusawa, K. Ieki, Jungsang Kim, D. Karlen, S. Y. Suzuki, Kate Scholberg, R. J. Wilkes, M. Bass, A. C. Kaboth, M. Hartz, D. Dewhurst, C. Wilkinson, D. Sgalaberna, J. R. Wilson, C. Nielsen, C. Lister, T. Koga, E. Radicioni, D. L. Wark, C. McGrew, T. Hara, L. Koch, A. D. Marino, Y. Hayato, C. Andreopoulos, S. R. Dennis, A. Bravar, P. Jonsson, P. Sinclair, Institut de Physique Nucléaire de Lyon (IPNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire Leprince-Ringuet (LLR), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), T2K, Ministerio de Economía y Competitividad (España), Ministry of Education, Culture, Sports, Science and Technology (Japan), Natural Sciences and Engineering Research Council of Canada, Centre National de la Recherche Scientifique (France), Royal Society (UK), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Abe, K., Adam, J., Aihara, H., Andreopoulos, C., Aoki, S., Ariga, A., Assylbekov, S., Autiero, D., Barbi, M., Barker, G. . j., Barr, G., Bartet Friburg, P., Bass, M., Batkiewicz, M., Bay, F., Berardi, V., Berger, B. . e., Berkman, S., Bhadra, S., Blaszczyk, F. . d. . m., Blondel, A., Bolognesi, S., Bordoni, S., Boyd, S. . b., Brailsford, D., Bravar, A., Bronner, C., Buchanan, N., Calland, R. . g., Caravaca Rodríguez, J., Cartwright, S. . l., Castillo, R., Catanesi, M. . g., Cervera, A., Cherdack, D., Chikuma, N., Christodoulou, G., Clifton, A., Coleman, J., Coleman, S. . j., Collazuol, G., Connolly, K., Cremonesi, L., Dabrowska, A., Danko, I., Das, R., Davis, S., de Perio, P., DE ROSA, Gianfranca, Dealtry, T., Dennis, S. . r., Densham, C., Dewhurst, D., Di Lodovico, F., Di Luise, S., Dolan, S., Drapier, O., Duffy, K., Dumarchez, J., Dytman, S., Dziewiecki, M., Emery Schrenk, S., Ereditato, A., Escudero, L., Ferchichi, C., Feusels, T., Finch, A. . j., Fiorentini, G. . a., Friend, M., Fujii, Y., Fukuda, Y., Furmanski, A. . p., Galymov, V., Garcia, A., Giffin, S., Giganti, C., Gilje, K., Goeldi, D., Golan, T., Gonin, M., Grant, N., Gudin, D., Hadley, D. . r., Haegel, L., Haesler, A., Haigh, M. . d., Hamilton, P., Hansen, D., Hara, T., Hartz, M., Hasegawa, T., Hastings, N. . c., Hayashino, T., Hayato, Y., Hearty, C., Helmer, R. . l., Hierholzer, M., Hignight, J., Hillairet, A., Himmel, A., Hiraki, T., Hirota, S., Holeczek, J., Horikawa, S., Hosomi, F., Huang, K., Ichikawa, A. . k., Ieki, K., Ieva, M., Ikeda, M., Imber, J., Insler, J., Irvine, T. . j., Ishida, T., Ishii, T., Iwai, E., Iwamoto, K., Iyogi, K., Izmaylov, A., Jacob, A., Jamieson, B., Jiang, M., Johnson, S., Jo, J. . h., Jonsson, P., Jung, C. . k., Kabirnezhad, M., Kaboth, A. . c., Kajita, T., Kakuno, H., Kameda, J., Kanazawa, Y., Karlen, D., Karpikov, I., Katori, T., Kearns, E., Khabibullin, M., Khotjantsev, A., Kielczewska, D., Kikawa, T., Kilinski, A., Kim, J., King, S., Kisiel, J., Kitching, P., Kobayashi, T., Koch, L., Koga, T., Kolaceke, A., Konaka, A., Kopylov, A., Kormos, L. . l., Korzenev, A., Koshio, Y., Kropp, W., Kubo, H., Kudenko, Y., Kurjata, R., Kutter, T., Lagoda, J., Lamont, I., Larkin, E., Laveder, M., Lawe, M., Lazos, M., Lindner, T., Lister, C., Litchfield, R. . p., Longhin, A., Lopez, J. . p., Ludovici, L., Magaletti, L., Mahn, K., Malek, M., Manly, S., Marino, A. . d., Marteau, J., Martin, J. . f., Martins, P., Martynenko, S., Maruyama, T., Matveev, V., Mavrokoridis, K., Mazzucato, E., Mccarthy, M., Mccauley, N., Mcfarland, K. . s., Mcgrew, C., Mefodiev, A., Metelko, C., Mezzetto, M., Mijakowski, P., Miller, C. . a., Minamino, A., Mineev, O., Missert, A., Miura, M., Moriyama, S., Mueller, T. h. . a., Murakami, A., Murdoch, M., Murphy, S., Myslik, J., Nakadaira, T., Nakahata, M., Nakamura, K. . g., Nakamura, K., Nakayama, S., Nakaya, T., Nakayoshi, K., Nantais, C., Nielsen, C., Nirkko, M., Nishikawa, K., Nishimura, Y., Nowak, J., O’Keeffe, H. . m., Ohta, R., Okumura, K., Okusawa, T., Oryszczak, W., Oser, S. . m., Ovsyannikova, T., Owen, R. . a., Oyama, Y., Palladino, Vittorio, Palomino, J. . l., Paolone, V., Payne, D., Perevozchikov, O., Perkin, J. . d., Petrov, Y., Pickard, L., Pinzon Guerra, E. . s., Pistillo, C., Plonski, P., Poplawska, E., Popov, B., Posiadala Zezula, M., Poutissou, J. M., Poutissou, R., Przewlocki, P., Quilain, B., Radicioni, E., Ratoff, P. . n., Ravonel, M., Rayner, M. . a. . m., Redij, A., Reeves, M., Reinherz Aronis, E., Riccio, Ciro, Rodrigues, P. . a., Rojas, P., Rondio, E., Roth, S., Rubbia, A., Ruterbories, D., Rychter, A., Sacco, R., Sakashita, K., Sánchez, F., Sato, F., Scantamburlo, E., Scholberg, K., Schoppmann, S., Schwehr, J., Scott, M., Seiya, Y., Sekiguchi, T., Sekiya, H., Sgalaberna, D., Shah, R., Shaker, F., Shaw, D., Shiozawa, M., Short, S., Shustrov, Y., Sinclair, P., Smith, B., Smy, M., Sobczyk, J. . t., Sobel, H., Sorel, M., Southwell, L., Stamoulis, P., Steinmann, J., Still, B., Suda, Y., Suzuki, A., Suzuki, K., Suzuki, S. . y., Suzuki, Y., Tacik, R., Tada, M., Takahashi, S., Takeda, A., Takeuchi, Y., Tanaka, H. . k., Tanaka, H. . a., Tanaka, M. . m., Terhorst, D., Terri, R., Thompson, L. . f., Thorley, A., Tobayama, S., Toki, W., Tomura, T., Totsuka, Y., Touramanis, C., Tsukamoto, T., Tzanov, M., Uchida, Y., Vacheret, A., Vagins, M., Vasseur, G., Wachala, T., Wakamatsu, K., Walter, C. . w., Wark, D., Warzycha, W., Wascko, M. . o., Weber, A., Wendell, R., Wilkes, R. . j., Wilking, M. . j., Wilkinson, C., Williamson, Z., Wilson, J. . r., Wilson, R. . j., Wongjirad, T., Yamada, Y., Yamamoto, K., Yanagisawa, C., Yano, T., Yen, S., Yershov, N., Yokoyama, M., Yoo, J., Yoshida, K., Yuan, T., Yu, M., Zalewska, A., Zalipska, J., Zambelli, L., Zaremba, K., Ziembicki, M., Zimmerman, E. . d., Zito, M., and Żmuda, J.

Subjects
Particle physics, Nuclear and High Energy Physics, chemistry.chemical_element, Pion production, Astronomy & Astrophysics, MASS, Neutrino beam, PION-PRODUCTION, 7. Clean energy, 01 natural sciences, Physics, Particles & Fields, High Energy Physics - Experiment, Nuclear physics, Scattering, Cross section (physics), 0202 Atomic, Molecular, Nuclear, Particle And Plasma Physics, 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Neutron, 010306 general physics, Neutrino oscillation, Nuclear Experiment, 0206 Quantum Physics, Charged current, Physics, Science & Technology, hep-ex, 010308 nuclear & particles physics, Detector, Nuclear & Particles Physics, MODEL, 0201 Astronomical And Space Sciences, chemistry, Physical Sciences, High Energy Physics::Experiment, Neutrino, Carbon, Nuclear targets
Abstract

17 pages.- 21 figures, We report a measurement of the nu(mu) charged current quasielastic cross-sections on carbon in the T2K on-axis neutrino beam. The measured charged current quasielastic cross-sections on carbon at mean neutrino energies of 1.94 GeV and 0.93 GeV are (11.95 +/- 0.19(stat)(-1.47)(+1.82)(syst)) x 10(-39) cm(2)/neutron, and (10.64 +/- 0.37(stat)(-1.65)(+2.03)(syst)) x 10(-39) cm(2)/neutron, respectively. These results agree well with the predictions of neutrino interaction models. In addition, we investigated the effects of the nuclear model and the multi-nucleon interaction., It is a pleasure to thank Mr. Taino from Mechanical Support Co. for helping with the construction of INGRID. We thank the J-PARC staff for superb accelerator performance and the CERN NA61 collaboration for providing valuable particle production data. We acknowledge the support of MEXT, Japan; NSERC, NRC and CFI, Canada; CEA and CNRS/IN2P3, France; DFG, Germany; INFN, Italy; National Science Centre (NCN), Poland; RSF, RFBR, and MES, Russia; MINECO and ERDF funds, Spain; SNSF and SER, Switzerland; STFC, UK; and DOE, USA. We also thank CERN for the UA1/NOMAD magnet, DESY for the HERA-B magnet mover system, NII for SINET4, the WestGrid and SciNet consortia in Compute Canada, GridPP, UK. In addition, participation of individual researchers and institutions has been further supported by funds from ERC (FP7), EU; JSPS, Japan; Royal Society, UK; DOE Early Career program, USA.

Published
2015

6. Measurement of the nu(mu) charged current quasielastic cross section on carbon with the T2K on-axis neutrino beam

Author

Ministerio de Economía y Competitividad (España), Ministry of Education, Culture, Sports, Science and Technology (Japan), Natural Sciences and Engineering Research Council of Canada, Centre National de la Recherche Scientifique (France), Royal Society (UK), T2K Collaboration, Abe, Kou, Cervera Villanueva, Anselmo, Escudero Sánchez, Lorena, Izmaylov, A., Sorel, Michel, Stamoulis, Panagiotis, Ministerio de Economía y Competitividad (España), Ministry of Education, Culture, Sports, Science and Technology (Japan), Natural Sciences and Engineering Research Council of Canada, Centre National de la Recherche Scientifique (France), Royal Society (UK), T2K Collaboration, Abe, Kou, Cervera Villanueva, Anselmo, Escudero Sánchez, Lorena, Izmaylov, A., Sorel, Michel, and Stamoulis, Panagiotis

Abstract

We report a measurement of the nu(mu) charged current quasielastic cross-sections on carbon in the T2K on-axis neutrino beam. The measured charged current quasielastic cross-sections on carbon at mean neutrino energies of 1.94 GeV and 0.93 GeV are (11.95 +/- 0.19(stat)(-1.47)(+1.82)(syst)) x 10(-39) cm(2)/neutron, and (10.64 +/- 0.37(stat)(-1.65)(+2.03)(syst)) x 10(-39) cm(2)/neutron, respectively. These results agree well with the predictions of neutrino interaction models. In addition, we investigated the effects of the nuclear model and the multi-nucleon interaction.

Published
2015

7. Promising Targets and Current Clinical Trials in Metastatic Non-Squamous NSCLC

Author

Alona Zer and Natasha B. Leighl

Subjects
Cancer Research, Mini Review, medicine.medical_treatment, EGFR, Bioinformatics, NSCLC, lcsh:RC254-282, Receptor tyrosine kinase, intracellular pathways, Targeted therapy, medicine, ROS1, Lung cancer, biology, business.industry, Wnt signaling pathway, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, non-squamous, nuclear targets, Oncology, ALK, Trk receptor, biology.protein, Cancer research, Adenocarcinoma, Personalized medicine, business, novel targets
Abstract

Lung adenocarcinoma is the most common subtype of lung cancer today. With the discovery of epidermal growth factor receptor (EGFR) mutations, anaplastic lymphoma kinase (ALK) rearrangements, and effective targeted therapy, personalized medicine has become a reality for patients with lung adenocarcinoma. Here, we review potential additional targets and novel therapies of interest in lung adenocarcinoma including targets within the cell surface (receptor tyrosine kinases EGFR, human epidermal growth factor receptor 2, RET, ROS1, mesenchymal–epidermal transition, TRK), targets in intracellular signal transduction (ALK, RAS–RAF–MEK, PI3K–AKT–PTEN, WNT), nuclear targets such as poly-ADP ribose polymerase, heat shock protein 90, and histone deacetylase, and selected pathways in the tumor environment. With the evolving ability to identify specific molecular aberrations in patient tumors in routine practice, our ability to further personalize therapy in lung adenocarcinoma is rapidly expanding.

Published
2014
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8. Measurement of the Inclusive NuMu Charged Current Cross Section on Carbon in the Near Detector of the T2K Experiment

Author

J. R. Wilson, C. Nielsen, Justin Albert, N. Abgrall, C. Lister, F. Di Lodovico, T. Maruyama, R. A. Wendell, Vincenzo Berardi, Tomoko Ariga, G. Vasseur, J. H. Jo, J. Lagoda, M. Tada, C. Bojechko, R. J. Wilson, Alexander Finch, C. W. Walter, F. Khanam, G.D. Barr, Masashi Tanaka, A. P. Furmanski, V. Paolone, A. Jacob, K. Iyogi, E. D. Zimmerman, A. K. Ichikawa, L. Monfregola, S. Manly, P. Hamilton, S. R. Dennis, A. Bravar, M. Mezzetto, K. Ieki, M. Ieva, L. Magaletti, C. Giganti, S. Roth, J. Kameda, E. Kearns, D. Karlen, I. Karpikov, R. Tacik, O. Perevozchikov, M. Barbi, S. L. Cartwright, Hiroyuki Sekiya, R. J. Wilkes, T. Szeglowski, F. Bay, E. S. Pinzon Guerra, Y. Fukuda, Kendall Mahn, Akitaka Ariga, Michal Dziewiecki, K. Connolly, Th. A. Mueller, Ko Okumura, Y. Takeuchi, T. Dealtry, M. M. Tanaka, Antonin Vacheret, Masashi Yokoyama, Matthew T. Reeves, E. Poplawska, Minoru Otani, A. Missert, P. Guzowski, D. Ruterbories, C. Wilkinson, André Rubbia, Takaaki Kajita, G. D. Lopez, Y. Shustrov, M. Tzanov, P. Mijakowski, A. Zalewska, C. J. Metelko, D. Terhorst, D. Payne, D. Sgalaberna, Hiroaki Aihara, P. N. Ratoff, Shigeki Aoki, T. Kutter, K. Nakajima, M. Friend, P. Jonsson, J. Åmuda, B. E. Berger, B. Smith, E. Reinherz-Aronis, A. Clifton, C. Yanagisawa, E. Scantamburlo, M. J. Wilking, H. Kakuno, L. Zambelli, R.P. Kurjata, R. A. Johnson, Anne Robert, S. Giffin, S. W. Bentham, H. M. O'Keeffe, L. L. Kormos, K. K. Joo, T. Wachala, I. Z. Danko, M. B. Smy, Kazuhiro Suzuki, S. A. Dytman, Koh Ueno, V. Matveev, T. Akiri, K. S. McFarland, Tsuyoshi Nakaya, J. Steinmann, T. Hasegawa, Gareth J. Barker, M. Hierholzer, D. Naples, P. Sinclair, Yusuke Koshio, A. Hillairet, K. Gilje, C. K. Jung, P. Kitching, T. McLachlan, W. R. Kropp, M. O. Wascko, A. Konaka, S. Tobayama, J. Marzec, S. Emery, W. H. Toki, M. Ikeda, Dmitriy Beznosko, K. Nishikawa, Masato Shiozawa, Scott Davis, D. Hansen, A. Laing, D. R. Hadley, S. J. Coleman, S. Horikawa, Jan T. Sobczyk, J. P. Coleman, C. Touramanis, A. Haesler, F. Sanchez, S. J. Ives, Antonio Ereditato, N. Yershov, S. Bhadra, A. C. Weber, D. Brailsford, R. Poutissou, K. Laihem, P. Masliah, D. Kielczewska, M. Batkiewicz, P. Stamoulis, A. Dabrowska, Frédéric Dufour, T. Tomura, K. Koseki, E. L. Mathie, O. V. Mineev, A. Gaudin, A. T. Suzuki, J. F. Martin, S. B. Kim, N. Grant, D. G. Brook-Roberge, J. Y. Kim, G. Kogan, S. B. Boyd, G. Collazuol, Mark Scott, T. Lindner, G. De Rosa, D. Autiero, T. Nakadaira, Y. Obayashi, C. Densham, R. A. Owen, M. Zito, P. A. Rodrigues, A. Thorley, J.J. Gómez-Cadenas, M. Macaire, M. Szeptycka, A. Korzenev, M. Miura, M. Murdoch, S. Nakayama, S. Mine, S. Yen, T. Yuan, I. Kreslo, M. Dziomba, J. Caravaca Rodríguez, H.A. Tanaka, K. Kowalik, M. Posiadala, M. G. Catanesi, M. Y. Pac, Hidetoshi Kubo, M. R. Vagins, A. Blondel, Iain Alexander Bertram, Rhiju Das, J. Imber, J. M. Poutissou, C. Bronner, B. Jamieson, Yukika Nishimura, A. N. Khotjantsev, L. Southwell, J. Myslik, T. Duboyski, N. J. Buchanan, T. Golan, A. Murakami, C. A. Miller, Yu. Kudenko, A. Minamino, E. Radicioni, A. Himmel, R. G. Calland, D. Gudin, Yuki Fujii, K. Zaremba, D. L. Wark, Richard J.H. Smith, I. T. Lim, J. Holeczek, B. A. Popov, K. Huang, M. Malek, Atsushi Takeda, T. Hara, K. Mavrokoridis, J. Dumarchez, F. d. M. Blaszczyk, Y. Kanazawa, J. D. Perkin, J. Schwehr, A. D. Marino, M. Shibata, Kate Scholberg, A. Marchionni, M. Hartz, K. Nakayoshi, B. Kirby, Jan Kisiel, T. Nicholls, T. Nakai, Jing Wang, E. Rondio, T. Kobayashi, S. Di Luise, L. Cremonesi, N. McCauley, C. Hearty, A. Curioni, M. Ziembicki, J. Insler, P. Przewlocki, K. Sakashita, M. M. Khabibullin, R. L. Helmer, S. M. Oser, Lester D.R. Thompson, O. Drapier, Y. Seiya, S. Berkman, S. Kumaratunga, B. Still, R. Ohta, D. I. Scully, S. Short, J. P. A. M. de André, N. C. Hastings, P. Plonski, S. Murphy, F. Retiere, V. Palladino, T. Tsukamoto, A. Izmaylov, K. P. Lee, M. Day, M. Messina, A. Longhin, T. Ishida, A. Kolaceke, J. Marteau, Z. Williamson, A. V. Waldron, T. Nagasaki, J. Dobson, H. Kaji, T. Kikawa, M. Gonin, L. Escudero, Joshua Hignight, W. Oryszczak, D. Cherdack, K. Abe, R. Sacco, C. McGrew, Y. Hayato, C. Andreopoulos, T. Sekiguchi, L. Ludovici, M. Sorel, Yasunari Suzuki, M. D. Haigh, Y. Totsuka, Susumu Takahashi, Takahiro Hiraki, M. A.M. Rayner, T. Wongjirad, A. Kilinski, T. Ishii, P. de Perio, Yoshikazu Yamada, T. Okusawa, Jungsang Kim, S. Y. Suzuki, M. Bass, A. C. Kaboth, A. Cervera, R. Terri, M. Ravonel, M. Lawe, H. W. Sobel, C. Licciardi, G. Christodoulou, K. Nakamura, R. Castillo, Yuichi Oyama, R. P. Litchfield, I. Taylor, B. Quilain, S. Assylbekov, E. Frank, Marco Laveder, S. Moriyama, Koji Yamamoto, Masayuki Nakahata, Y. Uchida, T. J. Irvine, V. Galymov, E. Mazzucato, G. F. Pearce, Institut de Physique Nucléaire de Lyon (IPNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Leprince-Ringuet (LLR), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), T2K, Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), Ministerio de Economía y Competitividad (España), Centro Nacional de Física de Partículas, Astropartículas y Nuclear (España), Ministry of Education, Culture, Sports, Science and Technology (Japan), Abgrall, Nicolas, Blondel, Alain, Bravar, Alessandro, Dufour, Fanny, Haesler, Alexis, Korzenev, Alexander, Murphy, Sébastien, Ravonel Salzgeber, Melody, Rayner, Mark, Scantamburlo, Enrico, K., Abe, N., Abgrall, H., Aihara, T., Akiri, J. B., Albert, C., Andreopoulo, S., Aoki, A., Ariga, T., Ariga, S., Assylbekov, D., Autiero, M., Barbi, G. J., Barker, G., Barr, M., Ba, M., Batkiewicz, F., Bay, S. W., Bentham, V., Berardi, B. E., Berger, S., Berkman, I., Bertram, D., Beznosko, S., Bhadra, F. d. M., Blaszczyk, A., Blondel, C., Bojechko, S., Boyd, D., Brailsford, A., Bravar, C., Bronner, D. G., Brook Roberge, N., Buchanan, R. G., Calland, J., Caravaca Rodr?guez, S. L., Cartwright, R., Castillo, M. G., Catanesi, A., Cervera, D., Cherdack, G., Christodoulou, A., Clifton, J., Coleman, S. J., Coleman, G., Collazuol, K., Connolly, L., Cremonesi, A., Curioni, A., Dabrowska, I., Danko, R., Da, S., Davi, M., Day, J. P. A. M., de Andr?, P., de Perio, DE ROSA, Gianfranca, T., Dealtry, S. R., Denni, C., Densham, F., Di Lodovico, S., Di Luise, J., Dobson, O., Drapier, T., Duboyski, F., Dufour, J., Dumarchez, S., Dytman, M., Dziewiecki, M., Dziomba, S., Emery, A., Ereditato, L., Escudero, A. J., Finch, E., Frank, M., Friend, Y., Fujii, Y., Fukuda, A. P., Furmanski, V., Galymov, A., Gaudin, S., Giffin, C., Giganti, K., Gilje, T., Golan, J. J., Gomez Cadena, M., Gonin, N., Grant, D., Gudin, P., Guzowski, D. R., Hadley, A., Haesler, M. D., Haigh, P., Hamilton, D., Hansen, T., Hara, M., Hartz, T., Hasegawa, N. C., Hasting, Y., Hayato, C., Hearty, R. L., Helmer, M., Hierholzer, J., Hignight, A., Hillairet, A., Himmel, T., Hiraki, J., Holeczek, S., Horikawa, K., Huang, A. K., Ichikawa, K., Ieki, M., Ieva, M., Ikeda, J., Imber, J., Insler, T. J., Irvine, T., Ishida, T., Ishii, S. J., Ive, K., Iyogi, A., Izmaylov, A., Jacob, B., Jamieson, R. A., Johnson, J. H., Jo, P., Jonsson, K. K., Joo, C. K., Jung, A., Kaboth, H., Kaji, T., Kajita, H., Kakuno, J., Kameda, Y., Kanazawa, D., Karlen, I., Karpikov, E., Kearn, M., Khabibullin, F., Khanam, A., Khotjantsev, D., Kielczewska, T., Kikawa, A., Kilinski, J. Y., Kim, J., Kim, S. B., Kim, B., Kirby, J., Kisiel, P., Kitching, T., Kobayashi, G., Kogan, A., Kolaceke, A., Konaka, L. L., Kormo, A., Korzenev, K., Koseki, Y., Koshio, K., Kowalik, I., Kreslo, W., Kropp, H., Kubo, Y., Kudenko, S., Kumaratunga, R., Kurjata, T., Kutter, J., Lagoda, K., Laihem, A., Laing, M., Laveder, M., Lawe, K. P., Lee, C., Licciardi, I. T., Lim, T., Lindner, C., Lister, R. P., Litchfield, A., Longhin, G. D., Lopez, L., Ludovici, M., Macaire, L., Magaletti, K., Mahn, M., Malek, S., Manly, A., Marchionni, A. D., Marino, J., Marteau, J. F., Martin, T., Maruyama, J., Marzec, P., Masliah, E. L., Mathie, V., Matveev, K., Mavrokoridi, E., Mazzucato, N., Mccauley, K. S., Mcfarland, C., Mcgrew, T., Mclachlan, M., Messina, C., Metelko, M., Mezzetto, P., Mijakowski, C. A., Miller, A., Minamino, O., Mineev, S., Mine, A., Missert, M., Miura, L., Monfregola, S., Moriyama, Mueller, T. h. A., A., Murakami, M., Murdoch, S., Murphy, J., Myslik, T., Nagasaki, T., Nakadaira, M., Nakahata, T., Nakai, K., Nakajima, K., Nakamura, S., Nakayama, T., Nakaya, K., Nakayoshi, D., Naple, T. C., Nicholl, C., Nielsen, K., Nishikawa, Y., Nishimura, H. M., O?keeffe, Y., Obayashi, R., Ohta, K., Okumura, T., Okusawa, W., Oryszczak, S. M., Oser, M., Otani, R. A., Owen, Y., Oyama, M. Y., Pac, Palladino, Vittorio, V., Paolone, D., Payne, G. F., Pearce, O., Perevozchikov, J. D., Perkin, E. S., Pinzon Guerra, P., Plonski, E., Poplawska, B., Popov, M., Posiadala, J. M., Poutissou, R., Poutissou, P., Przewlocki, B., Quilain, E., Radicioni, P. N., Ratoff, M., Ravonel, M. A. M., Rayner, M., Reeve, E., Reinherz Aroni, F., Retiere, A., Robert, P. A., Rodrigue, E., Rondio, S., Roth, A., Rubbia, D., Ruterborie, R., Sacco, K., Sakashita, F., S?nchez, E., Scantamburlo, K., Scholberg, J., Schwehr, M., Scott, D. I., Scully, Y., Seiya, T., Sekiguchi, H., Sekiya, D., Sgalaberna, M., Shibata, M., Shiozawa, S., Short, Y., Shustrov, P., Sinclair, B., Smith, R. J., Smith, M., Smy, J. T., Sobczyk, H., Sobel, M., Sorel, L., Southwell, P., Stamouli, J., Steinmann, B., Still, A., Suzuki, K., Suzuki, S. Y., Suzuki, Y., Suzuki, T., Szeglowski, M., Szeptycka, R., Tacik, M., Tada, S., Takahashi, A., Takeda, Y., Takeuchi, H. A., Tanaka, M. M., Tanaka, M., Tanaka, I. J., Taylor, D., Terhorst, R., Terri, L. F., Thompson, A., Thorley, S., Tobayama, W., Toki, T., Tomura, Y., Totsuka, C., Touramani, T., Tsukamoto, M., Tzanov, Y., Uchida, K., Ueno, A., Vacheret, M., Vagin, G., Vasseur, T., Wachala, A. V., Waldron, C. W., Walter, J., Wang, D., Wark, M. O., Wascko, A., Weber, R., Wendell, R. J., Wilke, M. J., Wilking, C., Wilkinson, Z., Williamson, J. R., Wilson, R. J., Wilson, T., Wongjirad, Y., Yamada, K., Yamamoto, C., Yanagisawa, S., Yen, N., Yershov, M., Yokoyama, T., Yuan, A., Zalewska, L., Zambelli, K., Zaremba, M., Ziembicki, E. D., Zimmerman, M., Zito, and J., ?muda

Subjects
Nuclear and High Energy Physics, Higher education, Physics::Instrumentation and Detectors, Astrophysics::High Energy Astrophysical Phenomena, Neutrino reactions, Library science, FOS: Physical sciences, ddc:500.2, 01 natural sciences, 7. Clean energy, Neutrino scattering, High Energy Physics - Experiment, Nuclear physics, High Energy Physics - Experiment (hep-ex), 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Early career, 010306 general physics, Nuclear Experiment, Physics, 010308 nuclear & particles physics, business.industry, 4. Education, Nuclear Targets, T2K experiment, Física, Russian federation, Christian ministry, Angular dependence, High Energy Physics::Experiment, business
Abstract

T2K has performed the first measurement of nu(mu) inclusive charged current interactions on carbon at neutrino energies of similar to 1 GeV where the measurement is reported as a flux-averaged double differential cross section in muon momentum and angle. The flux is predicted by the beam Monte Carlo and external data, including the results from the NA61/SHINE experiment. The data used for this measurement were taken in 2010 and 2011, with a total of 10.8 x 10(19) protons-on-target. The analysis is performed on 4485 inclusive charged current interaction candidates selected in the most upstream fine-grained scintillator detector of the near detector. The flux-averaged total cross section is (phi) = (6.91 +/- 0.13(stat) +/- 0.84(syst)) x 10(-39) cm(2)/nucleon for a mean neutrino energy of 0.85 GeV., We thank the J-PARC accelerator team for the superb accelerator performance and CERN NA61 colleagues for providing essential particle production data and for their fruitful collaboration. We acknowledge the support of MEXT, Japan; NSERC, NRC and CFI, Canada; CEA and CNRS/IN2P3, France; DFG, Germany; INFN, Italy; Ministry of Science and Higher Education, Poland; RAS, RFBR and the Ministry of Education and Science of the Russian Federation; MEST and NRF, South Korea; MICINN and CPAN, Spain; SNSF and SER, Switzerland; STFC, UK; NSF and DOE, USA. We also thank CERN for their donation of the UA1/NOMAD magnet and DESY for the HERA-B magnet mover system. In addition, participation of individual researchers and institutions in T2K has been further supported by funds from: ERC (FP7), EU; JSPS, Japan; Royal Society, UK; DOE Early Career program, and the A. P. Sloan Foundation, USA.

Published
2013
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9. Measurement of the nu(mu) charged-current quasielastic cross section on carbon with the ND280 detector at T2K

Author

Abe, K, Adam, J, Aihara, H, Akiri, T, Andreopoulos, C, Aoki, S, Ariga, A, Assylbekov, S, Autiero, D, Barbi, M, Barker, GJ, Barr, G, Bartet-Friburg, P, Bass, M, Batkiewicz, M, Bay, F, Berardi, V, Berger, BE, Berkman, S, Bhadra, S, Blaszczyk, FDM, Blondel, A, Bojechko, C, Bolognesi, S, Bordoni, S, Boyd, SB, Brailsford, D, Bravar, A, Bronner, C, Calland, RG, Caravaca Rodriguez, J, Cartwright, SL, Castillo, R, Catanesi, MG, Cervera, A, Cherdack, D, Chikuma, N, Christodoulou, G, Clifton, A, Coleman, J, Coleman, SJ, Collazuol, G, Connolly, K, Cremonesi, L, Dabrowska, A, De Rosa, G, Danko, I, Das, R, Davis, S, de Perio, P, Dealtry, T, Dennis, SR, Densham, C, Dewhurst, D, Di Lodovico, F, Di Luise, S, Dolan, S, Drapier, O, Duboyski, T, Duffy, K, Dumarchez, J, Dytman, S, Dziewiecki, M, Emery-Schrenk, S, Ereditato, A, Escudero, L, Feusels, T, Finch, AJ, Fiorentini, GA, Friend, M, Fujii, Y, Fukuda, Y, Furmanski, AP, Galymov, V, Garcia, A, Giffin, S, Giganti, C, Gilje, K, Goeldi, D, Golan, T, Gonin, M, Grant, N, Gudin, D, Hadley, DR, Haegel, L, Haesler, A, Haigh, MD, Hamilton, P, Hansen, D, Hara, T, Hartz, M, Hasegawa, T, Hastings, NC, Hayashino, T, Hayato, Y, Hearty, C, Helmer, RL, Hierholzer, M, Hignight, J, Hillairet, A, Himmel, A, Hiraki, T, Hirota, S, Holeczek, J, Horikawa, S, Huang, K, Hosomi, F, Ichikawa, AK, Ieki, K, Ieva, M, Ikeda, M, Imber, J, Insler, J, Intonti, RA, Irvine, TJ, Ishida, T, Ishii, T, Iwai, E, Iwamoto, K, Iyogi, K, Izmaylov, A, Jacob, A, Jamieson, B, Jiang, M, Johnson, S, Jo, JH, Jonsson, P, Jung, CK, Kabirnezhad, M, Kaboth, AC, Kajita, T, Kakuno, H, Kameda, J, Kanazawa, Y, Karlen, D, Karpikov, I, Katori, T, Kearns, E, Khabibullin, M, Khotjantsev, A, Kielczewska, D, Kikawa, T, Kilinski, A, Kim, J, King, S, Kisiel, J, Kitching, P, Kobayashi, T, Koch, L, Kolaceke, A, Koga, T, Konaka, A, Kopylov, A, Kormos, LL, Korzenev, A, Koshio, Y, Kropp, W, Kubo, H, Kudenko, Y, Kurjata, R, Kutter, T, Lagoda, J, Lamont, I, Larkin, E, Laveder, M, Lawe, M, Lazos, M, Lindner, T, Lister, C, Litchfield, RP, Longhin, A, Lopez, JP, Ludovici, L, Magaletti, L, Mahn, K, Malek, M, Manly, S, Marino, AD, Marteau, J, Martin, JF, Martins, P, Martynenko, S, Maruyama, T, Matveev, V, Mavrokoridis, K, Ma, WY, Mazzucato, E, McCarthy, M, McCauley, N, McFarland, KS, McGrew, C, Mefodiev, A, Metelko, C, Mezzetto, M, Mijakowski, P, Miller, CA, Minamino, A, Mineev, O, Mine, S, Missert, A, Miura, M, Moriyama, S, Mueller, TA, Murakami, A, Murdoch, M, Murphy, S, Myslik, J, Nakadaira, T, Nakahata, M, Nakamura, KG, Nakamura, K, Nakamura, KD, Nakayama, S, Nakaya, T, Nakayoshi, K, Nantais, C, Nielsen, C, Nirkko, M, Nishikawa, K, Nishimura, Y, Nowak, J, O'Keeffe, HM, Ohta, R, Okumura, K, Okusawa, T, Oryszczak, W, Oser, SM, Ovsyannikova, T, Owen, RA, Oyama, Y, Palladino, V, Palomino, JL, Paolone, V, Payne, D, Perevozchikov, O, Perkin, JD, Petrov, Y, Pickard, L, Pickering, L, Guerra, ESP, Pistillo, C, Plonski, P, Poplawska, E, Popov, B, Posiadala-Zezula, M, Poutissou, J-M, Poutissou, R, Przewlocki, P, Quilain, B, Radicioni, E, Ratoff, PN, Ravonel, M, Rayner, MAM, Redij, A, Reeves, M, Reinherz-Aronis, E, Riccio, C, Rodrigues, PA, Rojas, P, Rondio, E, Roth, S, Rubbia, A, Ruterbories, D, Rychter, A, Sacco, R, Sakashita, K, Sanchez, F, Sato, F, Scantamburlo, E, Scholberg, K, Schoppmann, S, Schwehr, JD, Scott, M, Seiya, Y, Sekiguchi, T, Sekiya, H, Sgalaberna, D, Shah, R, Shaikhiev, A, Shaker, F, Shaw, D, Shiozawa, M, Shirahige, T, Short, S, Shustrov, Y, Sinclair, P, Smith, B, Smy, M, Sobczyk, JT, Sobel, H, Sorel, M, Southwell, L, Stamoulis, P, Steinmann, J, Still, B, Stewart, T, Suda, Y, Suzuki, A, Suzuki, K, Suzuki, SY, Suzuki, Y, Tacik, R, Tada, M, Takahashi, S, Takeda, A, Takeuchi, Y, Tanaka, HK, Tanaka, HA, Tanaka, MM, Terhorst, D, Terri, R, Thompson, LF, Thorley, A, Tobayama, S, Toki, W, Tomura, T, Touramanis, C, Tsukamoto, T, Tzanov, M, Uchida, Y, Vacheret, A, Vagins, M, Vallari, Z, Vasseur, G, Wachala, T, Wakamatsu, K, Walter, CW, Wark, D, Warzycha, W, Wascko, MO, Weber, A, Wendell, R, Wilkes, RJ, Wilking, MJ, Wilkinson, C, Williamson, Z, Wilson, JR, Wilson, RJ, Wongjirad, T, Yamada, Y, Yamamoto, K, Yanagisawa, C, Yano, T, Yen, S, Yershov, N, Yokoyama, M, Yoo, J, Yoshida, K, Yuan, T, Yu, M, Zalewska, A, Zalipska, J, Zambelli, L, Zaremba, K, Ziembicki, M, Zimmerman, ED, Zito, M, Zmuda, J, Ministerio de Economía y Competitividad (España), Ministry of Education, Culture, Sports, Science and Technology (Japan), Natural Sciences and Engineering Research Council of Canada, Centre National de la Recherche Scientifique (France), The Royal Society (UK), and Science and Technology Facilities Council (STFC)

Subjects
Science & Technology, hep-ex, Physics, Delta resonance, Astronomy & Astrophysics, nucl-ex, Nuclear & Particles Physics, Physics, Particles & Fields, High Energy Physics - Experiment, 0201 Astronomical And Space Sciences, 0202 Atomic, Molecular, Nuclear, Particle And Plasma Physics, GEV-C, SINGLE PION-PRODUCTION, NUCLEAR TARGETS, DELTA-RESONANCE, Physical Sciences, EXCITATION, RESONANCE REGION, Single-pion-production, SCATTERING, High Energy Physics::Experiment, EXCHANGE, 0206 Quantum Physics, Nuclear Experiment, TRUE ABSORPTION
Abstract

The Charged-Current Quasi-Elastic (CCQE) interaction, $\nu_{l} + n \rightarrow l^{-} + p$, is the dominant CC process at $E_\nu \sim 1$ GeV and contributes to the signal in accelerator-based long-baseline neutrino oscillation experiments operating at intermediate neutrino energies. This paper reports a measurement by the T2K experiment of the $\nu_{\mu}$ CCQE cross section on a carbon target with the off-axis detector based on the observed distribution of muon momentum ($p_\mu$) and angle with respect to the incident neutrino beam ($\theta_\mu$). The flux-integrated CCQE cross section was measured to be $(0.83 \pm 0.12) \times 10^{-38}\textrm{ cm}^{2}$ in good agreement with NEUT MC value of ${0.88 \times 10^{-38}} \textrm{ cm}^{2}$. The energy dependence of the CCQE cross section is also reported. The axial mass, $M_A^{QE}$, of the dipole axial form factor was extracted assuming the Smith-Moniz CCQE model with a relativistic Fermi gas nuclear model. Using the absolute (shape-only) $p_{\mu}cos\theta_\mu$ distribution, the effective $M_A^{QE}$ parameter was measured to be ${1.26^{+0.21}_{-0.18} \textrm{ GeV}/c^{2}}$ (${1.43^{+0.28}_{-0.22} \textrm{ GeV}/c^{2}}$).

Published
2015

10. Measurements of forward proton production with incident protons and charged pions on nuclear targets at the CERN Proton Synchroton

Author

Jordi Burguet-Castell, G. Giannini, L. Tortora, S.A. Bunyatov, A. Blondel, M. G. Catanesi, M. Kirsanov, E. Tcherniaev, M. Mezzetto, U. Gastaldi, Domizia Orestano, R. Schroeter, G.D. Barr, N. G. Polukhina, V. Tereschenko, E. Di Capua, A. Bagulya, V. Palladino, P. Zucchelli, Ilya Tsukerman, G.P. Skoro, A. Artamonov, A. Guglielmi, C. Meurer, L. Coney, G. Vidal-Sitjes, A. Kayis-Topaksu, L. Howlett, J.S. Graulich, S. Gianì, M. Sorel, Ghislain Grégoire, A. Cervera-Villanueva, G. Prior, R. Tsenov, Rob Edgecock, Ioannis Papadopoulos, C. Wiebusch, M. Bonesini, A. Grossheim, V. Grichine, U. Dore, A. Grant, Claus Gößling, P. Gorbunov, Silvia Borghi, E. Radicioni, Simone Gilardoni, Alexey Krasnoperov, F. Pastore, Malcolm Ellis, A. Ivanchenko, M. Bogomilov, D. W. Schmitz, P. Novella, J. Martín-Albo, D. Gibin, J.J. Gómez-Cadenas, Petar Temnikov, J. Panman, D. Kolev, C. N. Booth, S. Piperov, J. Dumarchez, F. Ferri, Vladimir Ivanchenko, M. C. Morone, B. A. Popov, A. Tonazzo, M. Apollonio, P. Chimenti, F. Bobisut, G. B. Mills, Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), APC - Neutrinos, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), HARP, Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), UCL - SST/IRMP - Institut de recherche en mathématique et physique, AstroParticule et Cosmologie (APC (UMR_7164)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Çukurova Üniversitesi, M., Apollonio, A., Artamonov, A., Bagulya, G., Barr, A., Blondel, F., Bobisut, M., Bogomilov, M., Bonesini, C., Booth, S., Borghi, S., Bunyatov, J., Burguet Castell, M., Catanesi, A., Cervera Villanueva, P., Chimenti, L., Coney, E., Di Capua, U., Dore, J., Dumarchez, R., Edgecock, M., Elli, F., Ferri, U., Gastaldi, S., Giani, Giannini, Gianrossano, D., Gibin, S., Gilardoni, P., Gorbunov, C., Gößling, J., Gómez Cadena, A., Grant, J., Graulich, G., Grégoire, V., Grichine, A., Grossheim, A., Guglielmi, L., Howlett, A., Ivanchenko, V., Ivanchenko, A., Kayis Topaksu, M., Kirsanov, D., Kolev, A., Krasnoperov, J., Martín Albo, C., Meurer, M., Mezzetto, G., Mill, M., Morone, P., Novella, D., Orestano, V., Palladino, J., Panman, I., Papadopoulo, F., Pastore, S., Piperov, N., Polukhina, B., Popov, G., Prior, E., Radicioni, D., Schmitz, R., Schroeter, G., Skoro, M., Sorel, E., Tcherniaev, P., Temnikov, V., Tereschenko, A., Tonazzo, L., Tortora, R., Tsenov, I., Tsukerman, G., Vidal Sitje, C., Wiebusch, P., Zucchelli, Blondel, Alain, Borghi, Silvia, Morone, Maria Cristina, Prior, Gersende, Schroeter, Raphaël, Çukurova Üniversitesi, Fen-Edebiyat Fakültesi, Fizik Bölümü, Apollonio, M, Artamonov, A, Bagulya, A, Barr, G, Blondel, A, Bobisut, F, Bogomilov, M, Bonesini, M, Booth, C, Borghi, S, Bunyatov, S, Burguet Castell, J, Catanesi, Mg, Cervera Villanueva, A, Chimenti, P, Coney, L, Di Capua, E, Dore, U, Dumarchez, J, Edgecock, R, Ellis, M, Ferri, F, Gastaldi, U, Giani, S, Giannini, G, Gibin, D, Gilardoni, S, Gorbunov, P, Gossling, C, Gomez Cadenas, Jj, Grant, A, Graulich, J, Gregoire, G, Grichine, V, Grossheim, A, Guglielmi, A, Howlett, L, Ivanchenko, A, Ivanchenko, V, Kayis Topaksu, A, Kirsanov, M, Kolev, D, Krasnoperov, A, Martin Albo, J, Meurer, C, Mezzetto, M, Mills, Gb, Morone, Mc, Novella, P, Orestano, Domizia, Palladino, V, Panman, J, Papadopoulos, I, Pastore, F, Piperov, S, Polukhina, N, Popov, B, Prior, G, Radicioni, E, Schmitz, D, Schroeter, R, Skoro, G, Sorel, M, Tcherniaev, E, Temnikov, P, Tereschenko, V, Tonazzo, A, Tortora, L, Tsenov, R, Tsukerman, I, Vidal Sitjes, G, Wiebusch, C, and Zucchelli, P.

Subjects
Nuclear and High Energy Physics, [PHYS.ASTR.HE]Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE], Physics::Instrumentation and Detectors, proton, nuclear targets, charged pions, FOS: Physical sciences, ddc:500.2, 01 natural sciences, High Energy Physics - Experiment, Nuclear physics, High Energy Physics - Experiment (hep-ex), Basic research, 0103 physical sciences, CERN, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], 010306 general physics, Nuclear Experiment, Inelastic proton scattering, Physics, Large Hadron Collider, 010308 nuclear & particles physics, Other reactions above meson production thresholds, [SDU.ASTR.HE]Sciences of the Universe [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE], Física, Pion-induced reactions, Research council, nuclear target, Physics::Accelerator Physics, HARP Experiment, High Energy Physics::Experiment, Humanities, Particle Physics - Experiment
Abstract

Measurements of the double-differential proton production cross-section d(2 sigma)/dpd Omega in the range of momentum 0.5 GeV/c, We gratefully acknowledge the help and support of the PS beam staff and of the numerous technical collaborators who contributed to the detector design, construction, commissioning and operation. In particular, we would like to thank G. Barichello, R. Brocard, K. Burin, V. Carassiti, F. Chignoli, D. Conventi, G. Decreuse, M. Delattre, C. Detraz, A. Domeniconi, M. Dwuznik, F. Evangelisti, B. Friend, A. Iaciofano, I. Krasin, D. Lacroix, J.-C. Legrand, M. Lobello, M. Lollo, J. Loquet, F. Marinilli, R. Mazza, J. Mulon, L. Musa, R. Nicholson, A. Pepato, P. Petev, X. Pons, I. Rusinov, M. Scandurra, E. Usenko, R. van der Vlugt, for their support in the construction of the detector and P. Dini for his contribution to Monte Carlo production. The collaboration acknowledges the major contributions and advice of M. Baldo-Ceolin, L. Linssen, M.T. Muciaccia and A. Pullia during the construction of the experiment. The collaboration is indebted to V. Ableev, F. Bergsma, P. Binko, E. Boter,M. Calvi, C. Cavion,M.Chizov, A. Chukanov, A. DeSanto, A. DeMin, M. Doucet, D. D¨ullmann, V. Ermilova, W. Flegel, Y. Hayato, A. Ichikawa, O. Klimov, T. Kobayashi, D. Kustov, M. Laveder, M. Mass, H. Meinhard, A. Menegolli, T. Nakaya, K. Nishikawa, M. Paganoni, F. Paleari, M. Pasquali, M. Placentino, V. Serdiouk, S. Simone, P.J. Soler, S. Troquereau, S. Ueda, A. Valassi and R. Veenhof for their contributions to the experiment. We acknowledge the contributions of V. Ammosov, G. Chelkov, D. Dedovich, F. Dydak, M. Gostkin, A. Guskov, D. Khartchenko, V. Koreshev, Z. Kroumchtein, I. Nefedov, A. Semak, J. Wotschack, V. Zaets and A. Zhemchugov to the work described in this paper. The experiment was made possible by grants from the Institut Interuniversitaire des Sciences Nucléaires and the Interuniversitair Instituut voor Kernwetenschappen (Belgium), Ministerio de Educación y Ciencia, Grant FPA2003-06921-c02-02 and Generalitat Valenciana, grant GV00-054-1, CERN (Geneva, Switzerland), the German Bundesministerium für Bildung und Forschung (Germany), the Istituto Nazionale di Fisica Nucleare (Italy), INR RAS (Moscow), the Russian Foundation for Basic Research (grant 08-02-00018), the Bulgarian Mational Science Fund (contract VU-F- 205/2006) and the Particle Physics and Astronomy Research Council (UK). We gratefully acknowledge their support.

Published
2010

11. Measurement of the inclusive nu(mu) charged current cross section on carbon in the near detector of the T2K experiment

Author

Ministerio de Economía y Competitividad (España), Centro Nacional de Física de Partículas, Astropartículas y Nuclear (España), Ministry of Education, Culture, Sports, Science and Technology (Japan), T2K Collaboration, Abe, Kou, Cervera Villanueva, Anselmo, Escudero Sánchez, Lorena, Gómez Cadenas, Juan José, Monfregola, Laura, Sorel, Michel, Stamoulis, Panagiotis, Ministerio de Economía y Competitividad (España), Centro Nacional de Física de Partículas, Astropartículas y Nuclear (España), Ministry of Education, Culture, Sports, Science and Technology (Japan), T2K Collaboration, Abe, Kou, Cervera Villanueva, Anselmo, Escudero Sánchez, Lorena, Gómez Cadenas, Juan José, Monfregola, Laura, Sorel, Michel, and Stamoulis, Panagiotis

Abstract

T2K has performed the first measurement of nu(mu) inclusive charged current interactions on carbon at neutrino energies of similar to 1 GeV where the measurement is reported as a flux-averaged double differential cross section in muon momentum and angle. The flux is predicted by the beam Monte Carlo and external data, including the results from the NA61/SHINE experiment. The data used for this measurement were taken in 2010 and 2011, with a total of 10.8 x 10(19) protons-on-target. The analysis is performed on 4485 inclusive charged current interaction candidates selected in the most upstream fine-grained scintillator detector of the near detector. The flux-averaged total cross section is (phi) = (6.91 +/- 0.13(stat) +/- 0.84(syst)) x 10(-39) cm(2)/nucleon for a mean neutrino energy of 0.85 GeV.

Published
2013

12. Electroproduction of Strangeness on Light Nuclei

Author

F. DOHRMANN, D. ABBOTT, A. AHMIDOUCH, P. AMBROZEWICZ, C.S. ARMSTRONG, J. ARRINGTON, R. ASATURYAN, K. ASSAMAGAN, S. AVERY, K. BAILEY, O.K. BAKER, S. BEEDOE, H. BITAO, H. BREUER, D.S. BROWN, R. CARLINI, J. CHA, N. CHANT, E. CHRISTY, A. COCHRAN, L. COLE, G. COLLINS, C. COTHRAN, J. CROWDER, W.J. CUMMINGS, S. DANAGOULIAN, F. DUNCAN, J. DUNNE, D. DUTTA, T. EDEN, M. ELAASAR, R. ENT, L. EWELL, H. FENKER, H.T. FORTUNE, Y. FUJII, L. GAN, H. GAO, K. GARROW, D.F. GEESAMAN, P. GUEYE, K. GUSTAFSSON, K. HAFIDI, J.O. HANSEN, W. HINTON, H.E. JACKSON, H. JUENGST, C. KEPPEL, A. KLEIN, D. KOLTENUK, Y. LIANG, J.H. LIU, A. LUNG, D. MACK, R. MADEY, P. MARKOWITZ, C.J. MARTOFF, D. MEEKINS, J. MITCHELL, T. MIYOSHI, H. MKRTCHYAN, R. MOHRING, S.K. MTINGWA, B. MUELLER, T.G. O’NEILL, G. NICULESCU, I. NICULESCU, D. POTTERVELD, J.W. PRICE, B.A. RAUE, P.E. REIMER, J. REINHOLD, J. ROCHE, P. ROOS, M. SARSOUR, Y. SATO, G. SAVAGE, R. SAWAFTA, R.E. SEGEL, A.YU. SEMENOV, S. STEPANYAN, V. TADEVOSIAN, S. TAJIMA, L. TANG, B. TERBURG, A. UZZLE, S. WOOD, H. YAMAGUCHI, C. YAN, L. YUAN, M. ZEIER, B. ZEIDMAN, and B. ZIHLMANN

Subjects
Physics, Light nucleus, Electroproduction, Nuclear Theory, Strangeness, Hyperons, Spectral function, Nuclear physics, TheoryofComputation_ANALYSISOFALGORITHMSANDPROBLEMCOMPLEXITY, Nuclear Experiment, Hypernuclear boundstates, Electroproduction of strangeness, Nuclear targets
Abstract

The A(e,e'K+)YX reaction has been investigated in Hall C at Jefferson Laboratory for 6 different targets. Data were taken for Q2)approx 0.35 and 0.5 GeV2) at a beam energy of 3.245GeV for 1)H, 2)H, 3)He, 4)He, C and Al targets. The missing mass spectra are fitted with Monte Carlo simulations taking into account the production of Lambda and Sigma0) hyperon production off the proton, and Sigma-) off the neutron. Models for quasifree production are compared to the data, excess yields close to threshold are attributed to FSI. Evidence for Lambda-hypernuclear bound states is seen for 3,4)He targets.

Published
2004

13. Leptoproduction of cumulative nucleons

Author

Braun, M. A., Vechernin, V. V., and Vlahović, B.

Subjects
nucleon leptoproduction, nuclear targets, Weizsäcker-Williams approximation
Abstract

Leptoproduction of nucleons on nuclear targets into the backward hemisphere is studied at relativistic subasymptotic energies and momenta. Spins are neglected. The relativistic internucleon potential is extracted from the appropriate photoproduction data. Different production mechanisms are shown to work together and interfere. Calculations show that whenever rescattering is possible, it gives the bulk of the contribution, except at very high Q2. The Weizsäcker-Williams approximation is found to generally reproduce only a small part of the total cross-section. Comparison with the data for A(e,e˘p) reaction at E=2.4 GeV shows a reasonable agreement., Proučavamo leptotvorbu nukleona u nukleanrim metama u stražnju polusferu na relativističkim podasimptotskim energijama i impulsima. Zanemarujemo spinove. Relativistički međunukleonski potencijal izvodimo iz odnosnih podataka za fototvorbu. Pokazujemo da je djelotvorno više mehanizama koji interferiraju. Ako je višestruko raspršenje moguće, računi pokazuju da ono i prevladava, izuzev za vrlo velike Q2 . Nalazimo da Weizsäcker-Williamsovo približenje dobro opisuje samo mali dio ukupnog udarnog presjeka. Usporedba s podacima za reakciju A(e,e′p) na E = 2.4 GeV pokazuje dobro slaganje.

Published
2004

14. Electroproduction of Strangeness on Light Nuclei

Author

Dohrmann, F., Abbott, D., Ahmidouch, A., Ambrozewicz, P., Armstrong, C. S., Arrington, J., Asaturyan, R., Assamagan, K., Avery, S., Bailey, K., Baker, O. K., Beedoe, S., Bitao, H., Breuer, H., Brown, D. S., Carlini, R., Cha, J., Chant, N., Christy, E., Cochran, A., Cole, L., Collins, G., Cothran, C., Crowder, J., Cummings, W. J., Danagoulian, S., Duncan, F., Dunne, J., Dutta, D., Eden, T., Elaasar, M., Ent, R., Ewell, L., Fenker, H., Fortune, H. T., Fujii, Y., Gan, L., Gao, H., Garrow, K., Geesaman, D. F., Gueye, P., Gustafsson, K., Hafidi, K., Hansen, J. O., Hinton, W., Jackson, H. E., Juengst, H., Keppel, C., Klein, A., Koltenuk, D., Liang, Y., Liu, J. H., Lung, A., Mack, D., Madey, R., Markowitz, P., Martoff, C. J., Meekins, D., Mitchell, J., Miyoshi, T., Mkrtchyan, H., Mohring, R., Mtingwa, S. K., Mueller, B., O'Neill, T. J., Niculescu, G., Niculescu, I., Potterveld, D. H., Price, J. W., Raue, B. A., Reimer, P. E., Reinhold, J., Roche, J., Roos, P., Sarsour, M., Sato, Y., Savage, G., Sawafta, R., Segel, R. E., Semenov, A. Y., Stepanyan, S., Tadevosian, V., Tajima, S., Tang, L., Terburg, B., Uzzle, A., Wood, S., Yamaguchi, H., Yan-1, C., Yan-2, C., Yuan, L., Zeier, M., Zeidman, B., Zihlmann, B., Dohrmann, F., Abbott, D., Ahmidouch, A., Ambrozewicz, P., Armstrong, C. S., Arrington, J., Asaturyan, R., Assamagan, K., Avery, S., Bailey, K., Baker, O. K., Beedoe, S., Bitao, H., Breuer, H., Brown, D. S., Carlini, R., Cha, J., Chant, N., Christy, E., Cochran, A., Cole, L., Collins, G., Cothran, C., Crowder, J., Cummings, W. J., Danagoulian, S., Duncan, F., Dunne, J., Dutta, D., Eden, T., Elaasar, M., Ent, R., Ewell, L., Fenker, H., Fortune, H. T., Fujii, Y., Gan, L., Gao, H., Garrow, K., Geesaman, D. F., Gueye, P., Gustafsson, K., Hafidi, K., Hansen, J. O., Hinton, W., Jackson, H. E., Juengst, H., Keppel, C., Klein, A., Koltenuk, D., Liang, Y., Liu, J. H., Lung, A., Mack, D., Madey, R., Markowitz, P., Martoff, C. J., Meekins, D., Mitchell, J., Miyoshi, T., Mkrtchyan, H., Mohring, R., Mtingwa, S. K., Mueller, B., O'Neill, T. J., Niculescu, G., Niculescu, I., Potterveld, D. H., Price, J. W., Raue, B. A., Reimer, P. E., Reinhold, J., Roche, J., Roos, P., Sarsour, M., Sato, Y., Savage, G., Sawafta, R., Segel, R. E., Semenov, A. Y., Stepanyan, S., Tadevosian, V., Tajima, S., Tang, L., Terburg, B., Uzzle, A., Wood, S., Yamaguchi, H., Yan-1, C., Yan-2, C., Yuan, L., Zeier, M., Zeidman, B., and Zihlmann, B.

Abstract

The A(e,e'K+)YX reaction has been investigated in Hall C at Jefferson Laboratory for 6 different targets. Data were taken for Q2)approx 0.35 and 0.5 GeV2) at a beam energy of 3.245GeV for 1)H, 2)H, 3)He, 4)He, C and Al targets. The missing mass spectra are fitted with Monte Carlo simulations taking into account the production of Lambda and Sigma0) hyperon production off the proton, and Sigma-) off the neutron. Models for quasifree production are compared to the data, excess yields close to threshold are attributed to FSI. Evidence for Lambda-hypernuclear bound states is seen for 3,4)He targets.

Published
2003

15. Structural Studies of a New Nuclear Target for EGF Receptor Tyrosine Kinase

Author

CORNELL UNIV ITHACA NY, Calero, Guillermo A., Cerione, Rick, Clardy, Jon, CORNELL UNIV ITHACA NY, Calero, Guillermo A., Cerione, Rick, and Clardy, Jon

Abstract

This project involves structural studies of a nuclear target for the EGE receptor, and the elated Neu/ErbB2 tyrosine kinase, named the CBC for RNA-capped binding protein complex. The CBC consists of two subunits, CBP20 (Mr 18 kDa) and CBP80 (Mr 90 kda), and undergoes a growth factor (EGE, heregulin)-dependent binding of RNAs transcribed by the RNA polymerase II at a 5' cap structure that consists of a guanosine residue methylated at the N7 position. This represents a first key step in the cap-dependent splicing of precursor messenger RNA (mRNA) and in the mucleocytoplasmic transport of U snRNAs which are necessary for the formation of the spliceosome complexes. While, EGF stimulates CBC activity, it is most strongly stimulated by heregulin, an activator of the Neu/ErbB2 tyrosine kinase, and appears to be constitutive in breast cancer where Neu/ErbB2 expression is high. Thus, we believe that the CBC represents an exciting nuclear target for receptor tyrosine kinases, linking growth factor-dependent gene expression to RNA processing. We have solved the atomic structure of the CBC alone and in complex with the cap structure analog m7GpppG at 2.1 A. The atomic structure of this triple complex - represents the second eukaryotic cap binding structure solved to date and reveals interesting aspects of capped RNA binding and regulation., The original document contains color images. All DTIC reproductions will be in black and white.

Published
2002

16. New results on perturbative colour transparency in quasi-exclusive electroproduction

Author

Jain, Pankaj, Kundu, Bijoy, Ralston, John, and Samuelsson, Jim

Subjects
proton and pion quasi-exclusive electroproduction, nuclear targets, perturbative QCD formalism, hadronic electromagnetic form factors, colour transparency ratio
Abstract

We review the perturbative QCD formalism of hadronic electromagnetic form factors and the colour transparency ratio for quasi-exclusive electroproduction of the proton and pion from nuclear targets. We have completed the first full calculations including all leading-order quark subprocesses and integrations over distribution amplitudes, including Sudakov effects. For the case of the proton, the calculated result shows scaling beyond Q2 = 10 GeV2. The calculation incorporating filtering due to the nuclear medium is cleaner than the corresponding calculation in free space because of attenuation of large distance amplitudes. We find that the colour transparency ratio is rather insensitive to theoretical uncertainties inherent in the perturbative formalism, such as the choice of the hadron distribution amplitude., Opisuje se formalizam perturbativne QCD za hadronske elektromagnetske faktore oblika i omjer providnosti boje poluisključive elektrotvorbe protona i piona u nuklearnim metama. Završili smo prvi potpun račun, uključivši sve vodeće kvarkovske potprocese i integracije preko raspodjelnih amplituda, uključivši i Sudakove učinke. Rezultat za proton pokazuje sličnost dalje od Q2 = 10 GeV2 . Račun s filtriranjem uzrokovanim nuklearnom sredinom je pouzdaniji od odgovarajućeg računa u slobodnom prostoru zbog slabljenja amplituda na velikim udaljenostima. Nalazimo da je omjer providnosti boje vrlo neosjetljiv na teorijske neodređenosti perturbativnog formalizma, kao što je odabir amplitude hadronske raspodjele.

Published
1999

17. Nuclear targets, recoil ion catchers and reaction chambers

Author

Dionisio, J.S. J.S., Vieu, Ch, Schück, Carsten, Collatz, R., Meunier, Robert, Ledu, D., Folger, Helmut, Lafoux, A., Lagrange, J.M. J.M., Pautrat, Michèle, Waast, Bernard, Phillips, W.R. W.R., Blunt, David, Durell, J.L. J.L., Varley, B.J. B.J., Dagnall, P.G. P.G., Dorning, S.J. S.J., Jones, M.A. M.A., Smith, A.G. A.G., Bacelar, Jose C S, Urban, Waldemar, Rzaca-Urban, Teresa, Amzal, N., Meliani, Z., Vanhorenbeeck, Jean, Passoja, A., Dionisio, J.S. J.S., Vieu, Ch, Schück, Carsten, Collatz, R., Meunier, Robert, Ledu, D., Folger, Helmut, Lafoux, A., Lagrange, J.M. J.M., Pautrat, Michèle, Waast, Bernard, Phillips, W.R. W.R., Blunt, David, Durell, J.L. J.L., Varley, B.J. B.J., Dagnall, P.G. P.G., Dorning, S.J. S.J., Jones, M.A. M.A., Smith, A.G. A.G., Bacelar, Jose C S, Urban, Waldemar, Rzaca-Urban, Teresa, Amzal, N., Meliani, Z., Vanhorenbeeck, Jean, and Passoja, A.

Abstract

The main features of nuclear targets, recoil ion catchers and reaction chambers used in nuclear spectroscopic investigations involving in-beam multi-e-γ spectrometers are discussed. The relative importance of the δ-ray background due to the accelerated ion-target and the recoil-ion-target interaction is estimated. Its impact on the prompt low-energy electron measurements is stressed. Finally a few general features of the interplay between accelerated ion beams, targets and recoil ion catchers particularly relevant for these measurements are broadly discussed and illustrated with typical examples of in-beam e-γ studies. © 1998 Elsevier Science B. V. All rights reserved., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
1998

18. Major Crimes as Analogs to Potential Threats to Nuclear Facilities and Programs

Author

RAND CORP SANTA MONICA CA, Reinstedt, R. N., Westbury, Judith, RAND CORP SANTA MONICA CA, Reinstedt, R. N., and Westbury, Judith

Abstract

This Note is part of an ongoing investigation into the problem of potential and actual criminal adversaries of U.S. nuclear facilities and programs. Because of the low level of criminal activity against nuclear targets in the United States, The Rand Corporation has employed an analogous methodology to study this subject. Rand developed over several years a surrogate data base consisting of nonnuclear crimes that are analogous to potential incidents against nuclear facilities and programs. The data base contains 121 sophisticated and high-value burglaries, robberies, and other "conventional" crimes. Data on 45 of these crimes were taken directly from an earlier Rand study and an additional 76 crimes were selected for this document. Most of the information comes from newspaper and journal articles, and is subject to their errors and limitations. The data base was analyzed for information such as insider involvement, number of perpetrators, value of loot, type of crime, violence, coercion of employees, and use of deception. The purpose of the document is not to declare what should be done by those responsible for the security of nuclear facilities and materials, but to emphasize areas of particular vulnerability as observed in the analogous data base. Among the inferences and observations are the following: the higher the value of the loot the more likely that insiders participated; the higher the value of the loot the more perpetrators are likely to be involved; crimes involving insiders have an unusually high rate of apprehension; insiders can pose a great threat to nuclear security for a variety of reasons and in a number of ways; a high number of crimes occur while loot is in transit; crimes employing deception or coercion are very successful; his authority and/or access often determines whether an insider will use deception; and crimes of coercion usually have as their victims employees with authority and access. Synopses of each of the 121 crimes are provided., This report replaces ADE750244.

Published
1980

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