23 results on '"Zulqarnain, M."'
Search Results
2. Spinel ferrites having conductive grains, resistive interfacial boundaries and relaxation mechanism for possible supercapacitor applications
- Author
-
Zulqarnain, M., Ali, S.S., Yaqub, Muhammad Atif, Wan, C.H., Khan, M.I., Riaz, M., Laref, A., and Amami, Mongi
- Published
- 2024
- Full Text
- View/download PDF
3. Superparamagnetic contributions, optical band gap tuning and dominant interfacial resistive mechanisms in ferrites nanostructures
- Author
-
Zulqarnain, M., Ali, S.S., Hira, Uzma, Feng, J.F., Khan, M.I., Rizwan, M., Javed, K., Farid, Ghulam, and Hasan, M.S.
- Published
- 2022
- Full Text
- View/download PDF
4. Transformational leadership, corporate social responsibility, organizational innovation, and organizational performance: Symmetrical and asymmetrical analytical approaches
- Author
-
Khan, H.U.R., Ali, M., Olya, H.G.T., Zulqarnain, M., and Khan, Z.R.
- Abstract
This study examines the relationship between transformational leadership and organizational performance by evaluating the mediatory role of corporate social responsibility (CSR) and organizational innovation which has received considerably less attention in the literature. This study introduces CSR and organizational innovation as potential mediators of relationships between the key constructs of transformational leadership and organizational performance. Sufficient direct and mediation effects of predictors were tested using partial least squares structural equation modelling (PLS-SEM) with data from 396 French firms. Sufficient configurations of the predictors indicating high and low scores of performance were explored using fuzzy set qualitative comparative analysis (fsQCA). The PLS-SEM results show that both direct and indirect effects of transformational leadership on performance are significant. The fsQCA results reveal that a combination of CSR and transformational leadership leads to high performance. Alternately, high performance results from high innovation. This empirical study contributes to the current knowledge by applying both symmetrical and asymmetrical approaches to indicate performance at an organizational level. This study discusses the findings and provides theoretical, managerial, and research implications.
- Published
- 2018
5. A 52 μw Heart-Rate Measurement Interface Fabricated on a Flexible Foil with A-IGZO TFTs
- Author
-
Zulqarnain, M., Stanzione, S., Steen, J.L.P.J. van der, Gelinck, G.H., Myny, K., Abdinia, S., and Cantatore, E.
- Subjects
Wearable applications ,Wireless communications ,Experimental characterization ,Heart rate measurements ,IGZO ,Thin film transistors ,Bio-signal read out ,Heart ,Semiconducting indium compounds ,1/F noise ,Pulse width modulation ,voltage to pulse width conversion ,Fabrication ,Wireless telecommunication systems ,PWM ,Biosignals ,Pulsewidths - Abstract
This paper presents a 52 μW heart-rate measurement interface for wearable applications, fabricated on a flexible foil with a-IGZO TFTs. The interface consists of a cascaded diode-connected load preamplifier with a gain of 22 dB in 3 kHz bandwidth. The output is provided as a binary PWM waveform, which can be sent to a reader device using wireless communication. Voltage to pulse-width conversion is achieved with a simple and power minimalistic approach, which exploits a reset integrator. Experimental characterization demonstrates an overall low-frequency gain of the system equal to 25 msec/V and an input referred noise of 186.3 μV rms. In-vivo measurements have been performed, resulting in a 60 bpm heart-rate for a person at rest. © 2018 IEEE.
- Published
- 2018
6. Screening of antiviral activities in medicinal plants extracts against dengue virus using dengue NS2B-NS3 protease assay.
- Author
-
Rothan, H. A., Zulqarnain, M., Ammar, Y. A., Tan, E. C., Rahman, N. A., and Yusof, R.
- Published
- 2014
7. A Case of Coil-Assisted Retrograde Transvenous Obliteration to Treat Colonic Varices.
- Author
-
Hassan N, Zulqarnain M, Bader A, Hassan M, Mohamed I, Brown T, Jadhav K, and Ghoz H
- Abstract
Colonic variceal bleeding is a rare cause of lower gastrointestinal (GI) bleeding, which carries a high mortality rate. Due to limited data, the optimal management of colonic variceal bleeding is not known. Coil-assisted retrograde transvenous obliteration (CARTO) has been shown to be very effective in managing non-esophageal variceal bleeding, but only a few cases demonstrate its effectiveness in treating colonic variceal bleeding. Here we present a case of colonic variceal bleeding treated with CARTO in order to expand on the limited body of evidence showing its efficacy in effectively treating this rare cause of life-threatening GI bleeding., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Hassan et al.)
- Published
- 2024
- Full Text
- View/download PDF
8. Does Timing of Ileal Pouch-Anal Anastomosis Matter in Patients With Primary Sclerosing Cholangitis and Orthotopic Liver Transplantation? A Systematic Review and Meta-analysis.
- Author
-
Alsakarneh S, Ahmed M, Jaber F, Zulqarnain M, Karagozian R, Francis F, Farraye FA, and Hashash JG
- Abstract
Introduction: Pouchitis is the most common complication in patients with ileal pouch-anal anastomosis (IPAA), which can develop in up to 66% of patients. There is limited data on the effect of orthoptic liver transplantation (OLT) on the risk of developing pouchitis. We aimed to objectively assess whether OLT itself significantly modifies the risk of developing pouchitis in patients with overlap PSC and inflammatory bowel disease (IBD)., Method: We searched Medline, Scopus, and Embase databases from inception through September 2023 for studies that describe the outcomes of IPAA in patients with PSC and IBD who also have a history of OLT. Pooled proportions, Odds Ratio (OR), and 95% confidence intervals (CI) for data were calculated utilizing a random effects model. Using the Freeman-Turkey double arcsine transformation (FTT) method, the pooled weight-adjusted estimate of event rates for clinical outcomes in each group was also calculated. Heterogeneity between studies was assessed using the Cochrane Q statistic (I
2 )., Results: Seven studies with a total of 291 patients with a history of PSC, IBD, and OLT were identified. The pooled overall risk of pouchitis in PSC/IBD patients with a history of OLT was 65% (95% CI: 0.57-0.72), with no heterogeneity observed in the analysis (I2 = 0%). In a subgroup analysis of patients who had IPAA followed by OLT, 3 studies with 28 patients were included; the pooled risk of pouchitis after IPAA and OLT was 83% (95% CI: 0.71-0.94; I2 = 0%), which was significantly higher ( P < .001) than the OLT followed by IPAA group (59%; 95 CI: 0.48-0.71; I2 = 0%). There was no difference in the risk of pouchitis between OLT and non-OLT groups (OR = 1.36; 95% CI: 0.37-5.0)., Conclusions: Our meta-analysis revelaed that pouchitis is common in patients who underwent OLT for PSC, especially in those who had IPAA before the OLT. OLT before IPAA may reduce the risk of pouchitis. Further larger studies are warranted to reproduce this and investigate the reason behind this difference., Competing Interests: J.G.H. holds the position of clinical associate editor for Crohn’s & Colitis 360 and has been recused from reviewing or making decisions for the manuscript. F.A.F: AbbVie, Avalo Therapeutics, BMS, Braintree Labs, Fresenius Kabi, GI Reviewers, GSK, IBD Educational Group, Iterative Health, Janssen, Pharmacosmos, Pfizer, Sandoz Immunology, Sebela, Viatris. DSMB: Lilly. J.G.H: Advisory Board for BMS. Rest of authors have no conflict of interest. Disclosures: None to disclose., (© The Author(s) 2024. Published by Oxford University Press on behalf of Crohn's & Colitis Foundation.)- Published
- 2024
- Full Text
- View/download PDF
9. Predictive Factors of Non-Inflammatory Small Bowel Obstruction After Bowel Resection in Crohn's Patients.
- Author
-
Zulqarnain M, Jaber F, Jahagirdar V, Alsakarneh S, Gomez J, Stanton A, Patel N, Beniwal-Patel P, Stein D, Otterson M, and Yarur AJ
- Abstract
Background: The aim of the study was to investigate the risk factors associated with the development of small bowel obstruction (SBO) in Crohn's disease (CD) after small bowel resection (SBR) that are not due to active/recurrent inflammation., Methods: We conducted a retrospective cohort study of patients who had SBR for active or complicated CD. Abstracted data included demographics, phenotype, therapies for CD, endoscopic disease recurrence, and several surgical variables. The primary outcome was the development of non-inflammatory SBO (NI-SBO) within 5 years after SBR., Results: A total of 335 patients were included. The cumulative rates of NI-SBO at 6 months, 1 year, and 5 years were 5 (1.5%), 8 (2.4%), and 29 (8.9%), respectively. Variables associated with the development of NI-SBO were active macroscopic or microscopic inflammation in the surgical margins (13 (56%) vs. 65 (27%), P = 0.004), open resection (vs. laparoscopic resection) (12 (41.4%) vs. 60 (19.5%), P = 0.0006) and a higher median number of previous resections (2 (interquartile range (IQR) 2 - 3) vs. 1 (IQR 1 - 2), P = 0.0002). Only 21% of patients who developed NI-SBO required surgical intervention., Conclusions: The incidence of NI-SBO after SBR in CD is low and associated with inflammation at the margins of the resected bowel, previous bowel resections, and an open laparotomy approach. Most NI-SBOs resolve with medical management., Competing Interests: M. Zulqarnain: no conflict; F. Jaber: no conflict, V. Jahagirdar: no conflict; S. Alsakarneh: no conflict; A. Stanton: no conflict; N. Patel: no conflict; J. Gomez: no conflict; P. Beniwal-Patel: no conflict; D. Stein: AbbVie: consulting, speaking and teaching; Allergan: speaking; Bristol Myers Squibb: speaking and teaching; Pfizer: speaking and teaching; Takeda: speaking and teaching; M. F. Otterson: no conflict; A. Yarur: consultant Takeda, Bristol Myers Squibb, Pfizer, Arena., (Copyright 2024, Zulqarnain et al.)
- Published
- 2024
- Full Text
- View/download PDF
10. Inpatient outcomes of inflammatory bowel disease in hospitalized patients with COVID-19: analysis of a nationally representative sample.
- Author
-
Aldiabat M, Alsakarneh S, Daniel T, Butt MA, Jagdish B, Rock J, Sudan A, Al-Ahmad M, Jabri A, Kilani Y, Odah T, Alhuneafat L, Zulqarnain M, Hashash JG, and Ghoz H
- Abstract
Purpose: To compare the risks of adverse outcomes, including mortality, gastrointestinal bleeding, and venous thromboembolism, between COVID-19 patients with inflammatory bowel disease (IBD) and those without IBD., Methods: We analyzed data from the National Inpatient Sample between January and December 2020. The study included adult patients with Crohn's disease (CD) and ulcerative colitis (UC) who contracted COVID-19. Inpatient outcomes were compared between the IBD and non-IBD COVID-19 cohorts., Results: Out of 1,050,045 COVID-19 hospitalizations, 0.28% had CD (2954 patients) and 0.26% had UC (2794 patients). After adjusting for confounding factors, UC patients had a significantly higher risk of deep vein thrombosis compared to non-IBD patients, with an adjusted odds ratio (aOR) of 2.55 ( P < 0.001). However, CD patients did not show a significant association with deep vein thrombosis (aOR 1.29, P = 0.329). There were no significant associations between IBD patients (both UC and CD) and pulmonary embolism, nonvariceal gastrointestinal bleeding, or in-hospital mortality. UC patients had a longer average hospital stay (8.25 days) compared to non-IBD patients (adjusted mean difference 0.89, P = 0.007). Healthcare resource utilization was similar among the three groups., Conclusion: Our national study on COVID-19 hospitalizations indicates that patients with IBD have comparable rates of gastrointestinal bleeding, pulmonary embolism, and mortality as those without IBD. However, patients with UC hospitalized with COVID-19 have a higher risk of deep vein thrombosis than COVID-19 patients hospitalized without UC. Further research is needed to better understand the relationship between COVID-19 and IBD., Competing Interests: The authors report no funding or conflicts of interest., (Copyright © 2024 Baylor University Medical Center.)
- Published
- 2024
- Full Text
- View/download PDF
11. A comparison of career plans of gastroenterology fellows compared to fellows in other internal medicine subspecialties.
- Author
-
Alsakarneh S, Almeqdadi M, Jaber F, Beran A, Aldiabat M, Kilani Y, Reid AM, Zulqarnain M, Abughazaleh S, Duong N, and Clarkston W
- Abstract
Background: The career trajectory of medical professionals, particularly in specialized fields like gastroenterology, can significantly impact healthcare and research. This study aimed to analyze career choices among gastroenterology fellows in the US and investigate the factors influencing these choices., Methods: We utilized data from the American Medical Association on internal medicine subspecialty fellows. The study examined career plans of gastroenterology fellows and compared them with those of other subspecialties. A chi-square test was performed to assess differences in career choices and practice settings., Results: Among gastroenterology fellows, 46% opted for private practice, 28% pursued further training, and 26% chose academia. Notably, gastroenterology fellows were more inclined toward private practice than their counterparts in other subspecialties (46.3% vs 38.4%) and were less likely to pursue academic careers (25.6% vs 30.7%)., Conclusion: This study highlights a concerning trend among recent gastroenterology fellowship graduates favoring private practice over academic careers or additional training. To sustain and strengthen academic medicine in gastroenterology, interventions such as scholarships, mentorship programs, and loan repayment initiatives tailored to academic pursuits could play a crucial role., Competing Interests: The authors report no funding or conflicts of interest., (Copyright © 2023 Baylor University Medical Center.)
- Published
- 2023
- Full Text
- View/download PDF
12. Attention Aware Deep Learning Approaches for an Efficient Stress Classification Model.
- Author
-
Zulqarnain M, Shah H, Ghazali R, Alqahtani O, Sheikh R, and Asadullah M
- Abstract
In today's world, stress is a major factor for various diseases in modern societies which affects the day-to-day activities of human beings. The measurement of stress is a contributing factor for governments and societies that impacts the quality of daily lives. The strategy of stress monitoring systems requires an accurate stress classification technique which is identified via the reactions of the body to regulate itself to changes within the environment through mental and emotional responses. Therefore, this research proposed a novel deep learning approach for the stress classification system. In this paper, we presented an Enhanced Long Short-Term Memory(E-LSTM) based on the feature attention mechanism that focuses on determining and categorizing the stress polarity using sequential modeling and word-feature seizing. The proposed approach integrates pre-feature attention in E-LSTM to identify the complicated relationship and extract the keywords through an attention layer for stress classification. This research has been evaluated using a selected dataset accessed from the sixth Korea National Health and Nutrition Examination Survey conducted from 2013 to 2015 (KNHANES VI) to analyze health-related stress data. Statistical performance of the developed approach was analyzed based on the nine features of stress detection, and we compared the effectiveness of the developed approach with other different stress classification approaches. The experimental results shown that the developed approach obtained accuracy, precision, recall and a F1-score of 75.54%, 74.26%, 72.99% and 74.58%, respectively. The feature attention mechanism-based E-LSTM approach demonstrated superior performance in stress detection classification when compared to other classification methods including naïve Bayesian, SVM, deep belief network, and standard LSTM. The results of this study demonstrated the efficiency of the proposed approach in accurately classifying stress detection, particularly in stress monitoring systems where it is expected to be effective for stress prediction.
- Published
- 2023
- Full Text
- View/download PDF
13. First human case report of Crohn's disease with coexistent acute appendicitis treated by endoscopic retrograde appendicitis therapy.
- Author
-
Cui GX, Zulqarnain M, Lou QF, Shen HZ, Lyu W, Wang X, Huang H, Mohamoud Abdi H, Gu L, Fang S, Liu F, Ling L, Huang Y, Chu L, and Saeed S
- Abstract
Background: The coexistence of Crohn's disease (CD) and acute appendicitis (AA) is rare. In this situation, therapeutic experience is lacking and the strategy is paradoxical and intractable. Appendectomy is the gold standard for the treatment of AA whereas a nonsurgical approach is recommended for CD., Case Summary: A 17-year-old boy was hospitalized for right lower abdominal pain with fever of 3 days. He had the CD for 8 years. Two years ago, he underwent surgery for anal fistula with the complication of CD. His temperature was elevated at 38.3°C at admission. On physical examination, there was McBurney tenderness with mild rebound tenderness. Abdominal ultrasonography showed that the appendix was notably enlarged and dilated at 6.34 cm long and 2.76 cm wide. These findings were suggestive of uncomplicated AA in this patient with active CD. Endoscopic retrograde appendicitis therapy (ERAT) was performed. The patient had complete pain relief immediately after the procedure without tenderness in the right lower abdomen. During 18 mo follow-up, he had no more attacks in his right lower abdomen., Conclusion: ERAT was effective and safe in a CD patient with coexisting AA. Such cases can avoid surgery and its-related complications., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2023 Cui, Zulqarnain, Lou, Shen, Lyu, Wang, Huang, Mohamoud Abdi, Gu, Fang, Liu, Ling, Huang, Chu and Saeed.)
- Published
- 2023
- Full Text
- View/download PDF
14. A Bridge to Banding: Splenic Artery Embolization in Hepatosplenic Schistosomiasis.
- Author
-
Hassan N, Mohamed I, Rajab R, Campbell J, Zulqarnain M, Sadeddin E, and Ghoz H
- Abstract
Schistosomiasis is a parasitic infection endemic to sub-Saharan Africa. The severe form of disease, caused by deposition of Schistosoma eggs in the portal vein, is known as hepatosplenic schistosomiasis. We present a case of a 26-year-old woman with esophageal varices in the setting of hepatosplenic schistosomiasis. This patient underwent partial splenic artery embolization to treat thrombocytopenia secondary to splenic sequestration. After embolization and improvement of cell counts, the patient was successfully able to undergo variceal band ligation., (© 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.)
- Published
- 2023
- Full Text
- View/download PDF
15. A Rare Case of Primary Duodenal Plasmacytoma: An Incidental Finding.
- Author
-
Mohamed I, Haji M, Hassan N, Qasim H, Rajab R, Rajab R, Ibrahim A, Zulqarnain M, Sadeddin EZ, Ghoz H, and Mohammed S
- Abstract
Solitary extramedullary plasmacytoma (SEP) is a rare tumor due to the monoclonal proliferation of plasma cells without bone marrow involvement. Plasmacytomas are frequently encountered in bone or soft tissue but rarely occur in the gastrointestinal (GI) tract. They can present with a multitude of symptoms depending on their site. This report describes a case of SEP diagnosed as a duodenal ulcer (DU) during esophagogastroduodenoscopy (EGD) for iron deficiency anemia., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2023, Mohamed et al.)
- Published
- 2023
- Full Text
- View/download PDF
16. Endoscopic retrograde appendicitis therapy in the management of chronic fecalith appendicitis in a patient with ulcerative colitis: The first human case report.
- Author
-
Zulqarnain M, Cui G, Lyu W, Huang H, Wang X, Abdi HM, Gu L, Fang S, Liu F, and Ling L
- Subjects
- Male, Humans, Middle Aged, Endoscopy, Appendicitis complications, Appendicitis surgery, Fecal Impaction complications, Colitis, Ulcerative complications
- Abstract
To assess the effectiveness of endoscopic retrograde appendicitis therapy (ERAT) as a new technique and method for chronic fecalith appendicitis complicated by active ulcerative colitis. A 46-year-old male patient was admitted with right iliac fossa pain, tenderness, and raised inflammatory markers. A computed tomography (CT) scan of his abdomen confirmed a dilated appendix, which is considered chronic fecalith appendicitis combined with active ulcerative colitis. He was treated with an endoscopic retrograde appendicitis therapy procedure. The patient recovered well after the ERAT procedure and was discharged from the hospital in two days. On follow-up one year later, there was no recurrence of pain in his abdomen. In conclusion, ERAT could be seen as a different approach and be favored as a safer and more effective option in treating UC patients with appendicitis, especially those who are later in the course of the disease. Because of the ERAT procedure, such cases can avoid surgery and surgery-related complications. More research and issues must be addressed to demonstrate the efficacy and effectiveness of ERAT in appendicitis combined with UC., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2023 Zulqarnain, Cui, Lyu, Huang, Wang, Abdi, Gu, Fang, Liu and Ling.)
- Published
- 2023
- Full Text
- View/download PDF
17. Study on the Pakistan stock market using a new stock crisis prediction method.
- Author
-
Javid I, Ghazali R, Syed I, Zulqarnain M, and Husaini NA
- Subjects
- Pakistan, Bayes Theorem, Forecasting, Investments, Algorithms
- Abstract
A Stock market collapse occurs when stock prices drop by more than 10% across all main indexes. Predicting a stock market crisis is difficult because of the increased volatility in the stock market. Stock price drops can be triggered by a variety of factors, including corporate results, geopolitical tensions, financial crises, and pandemic events. For scholars and investors, predicting a crisis is a difficult endeavor. We developed a model for the prediction of stock crisis using Hybridized Feature Selection (HFS) approach. Firstly, we went for the suggestion of the HFS method for the removal of stock's unnecessary financial attributes. The Naïve Bayes approach, on the other hand, is used for the classification of strong fundamental stocks. In the third step, Stochastic Relative Strength Index (StochRSI) is employed to identify a stock price bubble. In the fourth step, we identified the stock market crisis point in stock prices through moving average statistics. The fifth is the prediction of stock crises by using deep learning algorithms such as Gated Recurrent Unit (GRU) and Long-Short Term Memory (LSTM). Root Mean Square Error (RMSE), Mean Squared Error (MSE) and Mean Absolute Error (MAE) are implemented for assessing the performance of the models. The HFS-based GRU technique outperformed the HFS-based LSTM method to anticipate the stock crisis. To complete the task, the experiments used Pakistan datasets. The researchers can look at additional technical factors to forecast when a crisis would occur in the future. With a new optimizer, the GRU approach may be improved and fine-tuned even more., Competing Interests: The authors have declared that no competing interests exist.
- Published
- 2022
- Full Text
- View/download PDF
18. Therapeutic Drug Monitoring in Perianal Fistulizing Crohn's Disease.
- Author
-
Zulqarnain M, Deepak P, and Yarur AJ
- Abstract
Perianal fistulas are a common complication of Crohn's disease (CD) that has, historically, been challenging to manage. Despite the strong available evidence that anti-tumor necrosis factor (anti-TNF) agents are useful in the treatment of perianal fistulizing Crohn's disease (PFCD), a significant number of these patients do not respond to therapy. The use of therapeutic drug monitoring (TDM) in patients with CD receiving biologic agents has evolved and is currently positioned as an important tool to optimize and guide biologic treatment. Considering the treatment of PFCD can represent a challenge; identifying novel tools to improve the efficacy of current treatments is an important unmet need. Given its emerging role in other phenotypes of Crohn's disease, the use of TDM could also offer an opportunity to enhance the effectiveness of available therapies and improve outcomes in the subset of patients with PFCD receiving biologics. Overall, there is mounting evidence that higher anti-TNF drug levels are associated with better rates of "fistula healing". However, studies have been limited by their use of subjective outcomes and observational designs. Ultimately, further interventional, randomized controlled trials looking into the relationship between drug exposure and fistula outcomes are needed.
- Published
- 2022
- Full Text
- View/download PDF
19. A comparative analysis on question classification task based on deep learning approaches.
- Author
-
Zulqarnain M, Khalaf Zager Alsaedi A, Ghazali R, Ghouse MG, Sharif W, and Aida Husaini N
- Abstract
Question classification is one of the essential tasks for automatic question answering implementation in natural language processing (NLP). Recently, there have been several text-mining issues such as text classification, document categorization, web mining, sentiment analysis, and spam filtering that have been successfully achieved by deep learning approaches. In this study, we illustrated and investigated our work on certain deep learning approaches for question classification tasks in an extremely inflected Turkish language. In this study, we trained and tested the deep learning architectures on the questions dataset in Turkish. In addition to this, we used three main deep learning approaches (Gated Recurrent Unit (GRU), Long Short-Term Memory (LSTM), Convolutional Neural Networks (CNN)) and we also applied two different deep learning combinations of CNN-GRU and CNN-LSTM architectures. Furthermore, we applied the Word2vec technique with both skip-gram and CBOW methods for word embedding with various vector sizes on a large corpus composed of user questions. By comparing analysis, we conducted an experiment on deep learning architectures based on test and 10-cross fold validation accuracy. Experiment results were obtained to illustrate the effectiveness of various Word2vec techniques that have a considerable impact on the accuracy rate using different deep learning approaches. We attained an accuracy of 93.7% by using these techniques on the question dataset., Competing Interests: The authors declare that they have no competing interests., (© 2021 Zulqarnain et al.)
- Published
- 2021
- Full Text
- View/download PDF
20. Bimetallic cobalt-iron diselenide nanorod modified glassy carbon electrode: an electrochemical sensing platform for the selective detection of isoniazid.
- Author
-
Sultan S, Zulqarnain M, Shah A, Firdous N, Nisar J, Ashiq MN, Bakhsh EM, and Khan SB
- Abstract
The increasing demand of a sensitive and portable electrochemical sensing platform in pharmaceutical analysis has developed widespread interest in preparing electrode materials possessing remarkable properties for the electrochemical determination of target drug analytes. Herein, we report the synthesis, characterization and application of bimetallic cobalt-iron diselenide (FeCoSe
2 ) nanorods as electrode modifiers for the selective detection of a commonly used anti-tuberculosis drug Isoniazid (INZ). We prepared FeCoSe2 nanorods by a simple hydrothermal route and characterized these by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive X-ray spectroscopy (EDX) and temperature-programmed reduction (TPR) techniques. The electrochemical characterization of FeCoSe2 modified GCE was performed by cyclic voltammetry (CV) and square wave anodic stripping voltammetry (SWASV). Under optimized experimental conditions, a linear current-concentration response was obtained for INZ in the range of 0.03-1.0 μM, with very low limit of detection 1.24 × 10-10 M. The real applicability of the designed FeCoSe2 /GCE sensing platform was adjudicated by the detection of INZ in biological samples., Competing Interests: There are no conflicts to declare., (This journal is © The Royal Society of Chemistry.)- Published
- 2021
- Full Text
- View/download PDF
21. FeCoSe 2 Nanoparticles Embedded in g-C 3 N 4 : A Highly Active and Stable bifunctional electrocatalyst for overall water splitting.
- Author
-
Zulqarnain M, Shah A, Khan MA, Jan Iftikhar F, and Nisar J
- Abstract
To investigate cost affordable and robust HER and OER catalysts with significant low overpotentials, we have successfully embedded FeCoSe
2 spheres on smooth surfaces of graphitic carbon nitride that demonstrated high stability and electrocatalytic activity for H2 production. We systematically analyzed the composition and morphology of Fex Co1-x Se2 /g-C3 N4 and attributed the remarkable electrochemical performance of the catalyst to its unique structure. Fe0.2 Co0.8 Se2 /g-C3 N4 showed a superior HER activity, with quite low overpotential value (83 mV at -20 mA cm-2 in 0.5 M H2 SO4 ) and a current density of -3.24, -7.84, -14.80, -30.12 mA cm-2 at 0 V (vs RHE) in Dulbecco's Phosphate-Buffered Saline (DPBS), artificial sea water (ASW), 0.5 M H2 SO4 and 1 M KOH, respectively. To the best of our knowledge, these are the highest reported current densities at this low potential value, showing intrinsic catalytic activity of the synthesized material. Also, the catalyst was found to deliver a high and stable current density of -1000 mA cm-2 at an overpotential of just 317 mV. Moreover, the synthesized catalyst delivered a constant current density of -30 mA cm-2 for 24 h without any noticeable change in potential at -0.2 V. These attributes confer our synthesized catalyst to be used for renewable fuel production and applications.- Published
- 2020
- Full Text
- View/download PDF
22. Needle stick injuries among nurses of two tertiary care hospitals of Lahore: A KAP study.
- Author
-
Hassnain S, Hassan Z, Amjad S, Zulqarnain M, Arshad K, and Zain Z
- Subjects
- Adult, Cross-Sectional Studies, Female, Humans, Pakistan epidemiology, Prevalence, Tertiary Care Centers, Young Adult, Needlestick Injuries epidemiology, Nurses statistics & numerical data, Occupational Injuries epidemiology
- Abstract
Objective: To estimate the prevalence of needle-stick injuries in female nurses of a public and private hospital and compare the findings., Methods: This cross-sectional study was conducted at one public and one private tertiary care hospital in Lahore, Pakistan, from March to June 2015, and comprised female nurses who were selected using non-probability purposive sampling. A structured questionnaire was used to interview the subjects. Data analysis was done using SPSS 17., Results: Of the 386 participants, there were 193(50%) from each of the two hospitals. The prevalence of needle-stick injuries was found to be 85(44%) in public and 51(26.4%) in the private hospital. The highest proportion of injuries in both hospitals occurred while disposing or recapping needles, 36(42.4%) and 32(62.7 %) in public and private hospitals, respectively, especially in the morning shift, i.e. 42(49.4%) in public and 32(62.7%) in private hospital. Syringe needles were mostly involved, 51(60%) in public and 45(88.2%) in private hospital., Conclusions: The prevalence of needle-stick injuries was higher in public hospital.
- Published
- 2017
23. Characterization of secreted recombinant Toxoplasma gondii surface antigen 2 (SAG2) heterologously expressed by the yeast Pichia pastoris.
- Author
-
Fong MY, Lau YL, and Zulqarnain M
- Subjects
- Animals, Antigens, Protozoan genetics, Antigens, Protozoan immunology, Blotting, Western, Electrophoresis, Polyacrylamide Gel, Enzyme-Linked Immunosorbent Assay, Female, Mice, Mice, Inbred ICR, Polymerase Chain Reaction, Protozoan Proteins genetics, Protozoan Proteins immunology, Recombinant Proteins immunology, Toxoplasma genetics, Toxoplasma immunology, Antigens, Protozoan metabolism, Pichia genetics, Protozoan Proteins metabolism, Recombinant Proteins metabolism, Toxoplasma metabolism
- Abstract
The surface antigen 2 (SAG2) gene of the protozoan parasite, Toxoplasma gondii, was cloned and extracellularly expressed in the yeast Pichia pastoris. The effectiveness of the secreted recombinant SAG2 (rSAG2-S) as a serodiagnosis reagent was assessed by western blots and ELISA. In the western blot assay, rSAG2-S reacted with all Toxoplasma-antibody positive human serum samples but not with Toxoplasma-negative samples. In the ELISA, rSAG2-S yielded sensitivity rates ranging from 80% (IgG negative, IgM positive) to 100% (IgG positive, IgM negative). In vivo experiments showed that serum from mice immunized with rSAG2-S reacted specifically with the native SAG2 of T. gondii. These mice were protected when challenged with live cells of T. gondii.
- Published
- 2008
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.