34 results on '"ZARAGOZA, F."'
Search Results
2. A Long-Term Symbiotic Relationship: Recruitment and Fidelity of the Crab Trapezia on Its Coral Host Pocillopora
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Canizales-Flores, H. M., primary, Rodríguez-Troncoso, A. P., additional, Rodríguez-Zaragoza, F. A., additional, and Cupul-Magaña, A. L., additional
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- 2021
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Catalog
3. Margarita Salas, referente indiscutible
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Ruiz Desviat, Lourdes, Ávila, J., Blanco, L., Cuezva, J. M., Vega, M. de, Mayor Menéndez, F., Mayor Zaragoza, F., UAM. Departamento de Biología Molecular, UAM. Departamento de Bioquímica, and Centro de Biología Molecular Severo Ochoa (CBM) more...
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Severo Ochoa ,Bioquímica y biología molecular ,Margarita Salas ,Científica ,Biología y Biomedicina / Biología - Published
- 2020
4. Influence of a selective histamine H3 receptor antagonist on hypothalamic neural activity, food intake and body weight
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Malmlöf, K, Zaragoza, F, Golozoubova, V, Refsgaard, H HF, Cremers, T, Raun, K, Wulff, B S, Johansen, P B, Westerink, B, and Rimvall, K
- Published
- 2005
5. Determinants of reef fish assemblages in tropical Oceanic islands
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Quimbayo, J. P., Dias, M. S., Kulbicki, Michel, Mendes, T. C., Lamb, R. W., Johnson, A. F., Aburto-Oropeza, O., Alvarado, J. J., Bocos, A. A., Ferreira, C. E. L., Garcia, E., Luiz, O. J., Mascarenas-Osorio, I., Pinheiro, H. T., Rodriguez-Zaragoza, F., Salas, E., Zapata, F. A., and Floeter, S. R. more...
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anthropogenic factors ,biogeographic factors ,energetic factors - Abstract
Diversity patterns are determined by biogeographic, energetic, and anthropogenic factors, yet few studies have combined them into a large-scale framework in order to decouple and compare their relative effects on fish faunas. Using an empirical dataset derived from 1527 underwater visual censuses (UVC) at 18 oceanic islands (five different marine provinces), we determined the relative influence of such factors on reef fish species richness, functional dispersion, density and biomass estimated from each UVC unit. Species richness presented low variation but was high at large island sites. High functional dispersion, density, and biomass were found at islands with large local species pool and distance from nearest reef. Primary productivity positively affected fish richness, density and biomass confirming that more productive areas support larger populations, and higher biomass and richness on oceanic islands. Islands densely populated by humans had lower fish species richness and biomass reflecting anthropogenic effects. Species richness, functional dispersion, and biomass were positively related to distance from the mainland. Overall, species richness and fish density were mainly influenced by biogeographical and energetic factors, whereas functional dispersion and biomass were strongly influenced by anthropogenic factors. Our results extend previous hypotheses for different assemblage metrics estimated from empirical data and confirm the negative impact of humans on fish assemblages, highlighting the need for conservation of oceanic islands. more...
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- 2019
6. Body size, reef area and temperature predict global reef-fish species richness across spatial scales
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Barneche, D. R., primary, Rezende, E. L., additional, Parravicini, V., additional, Maire, E., additional, Edgar, G. J., additional, Stuart-Smith, R. D., additional, Arias-González, J. E., additional, Ferreira, C. E. L., additional, Friedlander, A. M., additional, Green, A. L., additional, Luiz, O. J., additional, Rodríguez-Zaragoza, F. A., additional, Vigliola, L., additional, Kulbicki, M., additional, and Floeter, S. R., additional more...
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- 2018
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7. DÉCADA (2005-2014) DE LA EDUCACIÓN PARA UN FUTURO SOSTENIBLE
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Mayor Zaragoza, F.
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lcsh:Social Sciences ,lcsh:H ,FUTURO ,SOSTENIBLE ,EDUCACIÓN ,Social Sciences - Abstract
DÉCADA (2005-2014) DE LA EDUCACIÓN PARA UN FUTUROSOSTENIBLE
- Published
- 2010
8. Coral reef fish assemblages at Clipperton Atoll (Eastern Tropical Pacific) and their relationship with coral cover
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Ricart, A. M., Rodriguez-Zaragoza, F. A., Gonzalez-Salas, C., Ortiz, M., Cupul-Magana, A. L., and Adjeroud, Mehdi
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habitat structure ,species-habitat interaction ,spatial variation ,reef fish diversity - Abstract
Clipperton Atoll, one of the most isolated coral reefs worldwide, is of great scientific interest due to its geomorphology and high levels of endemism. This study explored the reef fish assemblage structure of Clipperton Atoll and its relationship with live coral cover. Nine stations were sampled at three sites and three depths (6, 12 and 20 m) around the reef, measuring fish species richness and biomass and hermatypic coral cover (at genus level). We evaluated variation in species richness, biomass and diversity of fish assemblages among sites and depths, as well as the relationship between the entire fish assemblage composition and live coral cover. The results showed that species richness and biomass were similar among sites, but differed across depths, increasing with depth. In contrast, diversity differed among sites but not among depths. Multivariate analyses indicated that fish assemblage composition differed among sites and depths in relation to changes in cover of coral of the genera Pocillopora, Porites, Pavona and Leptoseris, which dominate at different depths. The results showed that fish species richness and diversity were low at Clipperton Atoll and that, in isolated coral reefs with a low habitat heterogeneity and low human disturbance, live coral cover has a significant influence on the spatial variation of the reef fish assemblages. This study highlights the importance of coral habitat structure in shaping coral reef fish assemblages. more...
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- 2016
9. El sistema alimentario global: I-Definicion de un espacio
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Ballus, R., Xena, Y., Bragulat, E., and Zaragoza, F.
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disponibilidad, economia, politica, saber, alimentacion, sociedad, sistema dinamico, modelizacion matematica, prospectiva, availability, economy, politics, knowledge, food, society, dynamic systems, mathematical models, prospective, Food Consumption/Nutrition/Food Safety, Production Economics, Productivity Analysis, Public Economics, 3C(02-51), 9I(19-31), 12L(66), 15O(013), 17Q(1-2-3-5) - Abstract
Los autores desarrollan su modelos de sistema alimentario global, pesentado conceptualmente en anteriores publicaciones, basado en cuatro ejes basicos (disonibilidad, economia, politica y saber) dandole una estructura compresnbile, abierta y en la que se la plica una metodologia matematica que permite conocer la evolucion de los parametros y su prospectiva. Para ello, en el presente trabajo se pasa de los conceptos cualitativos a los cuantitativos. Cada eje se descompine, en tres subejes dando un total de 12, que identifican aspectos especificos de los pirimarios y que definen en este espacio las actividades y conceptos fundmentales del sistema agroalimentario y de tal forma que puedan seguir desarrollandose sus contenidos en aspectos de aun mas detalle, en un desarrollo fractal de base tetraedica. Para cada subeje se propone un primer parametro de evaluacion en base a valores en unidades, obtenibles en unidades de tiempo, habitualmente anos, de datos fiables publicados y compatibles con el modelo de estudios evolutivos y prospectivos presentados en el que se propone una variable vectorial para cada eje que toma valores en el simplex de tres partes y ajuste a un modelo lineal en coordenadas ILR (isometric logratio transformation). El modelo normaliza una estructura que da relieve al espacio agroalimentario global y perminte realizar estrategias propsectivas sobre el mismo en cada parametro y entre ellos. The authors develop their model of global food system, presented conceptually ine arlier publications, based on four basic axes (availability, economy, politics and knowledge) to give it an understandable open structure, and applying a mathematical methodology to it to enable the evolution of the parameters and its prospects to be known. To this end, this current study goes beyond the qualitative concepts to the quantitative ones. Each axis is broken down into three sub-axes giving a total of 12, that identify specific aspects of the primary ones and define the fundamental activities and concepts of the agri-food system in this space and in such a way that their contents can be developed further in even greater detail, in a fractal development on a tetrahedral base. A first evaluation parameter is proposed for each sub-axis based on values in units, that can be obtained, time units, years usually, from reliable published data and compatible with the model of evolutionary and prospective studies presented in which a variable vector for each axis is proposed that takes values in the simplex of three parts and adjusted to a lineal model in ILR ( isometric logratio transformation) coordinates. The model standardises a structure that highlights the global agri-food area and allows prospective strategies to be carried out the same subject, on each parameter or between them. more...
- Published
- 2013
10. Innovative Monte Carlo simulations for the accurate estimation of absorbed dose at organs at risk and the dose distribution in the eye treated with Ru-106 plaques
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Lorenzo Brualla, Zaragoza, F. J., Sempau, J., Fluehs, D., Luedemann, L., Zimmermann, B., Wittig, A., and Sauerwein, W.
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Medizin - Published
- 2012
11. Tiempo de viajar
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Zaragoza, F.
- Published
- 1992
12. Two Methylated Hexacyclic Cage Diketones
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Linetsky, M., primary, Zaragoza, F., additional, Bott, S. G., additional, and Marchand, A. P., additional
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- 1996
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13. Influence of a selective histamine H3 receptor antagonist on hypothalamic neural activity, food intake and body weight.
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Malmlöf, K., Zaragoza, F., Golozoubova, V., Refsgaard, H. H. F., Cremers, T., Raun, K., Wulff, B. S., Johansen, P. B., Westerink, B., and Rimvall, K.
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HISTAMINE , *BIOGENIC amines , *INFLAMMATORY mediators , *RECEPTOR antibodies , *INGESTION , *ABSORPTION (Physiology) , *BODY weight , *ANTHROPOMETRY - Abstract
OBJECTIVE:This study was conducted to elucidate whether antagonistic targeting of the histamine H3 receptor increases hypothalamic histamine levels, in parallel with decreases in food intake and body weight.METHODS:The competitive antagonist potency of a recently synthesized histamine H3 receptor antagonist, NNC 38-1049, was studied in intact HEK293 cells expressing human or rat histamine H3 receptor, in which NNC 38-1049 was allowed to antagonize the effect of the H3 receptor agonist R-α-methylhistamine on isoprenaline-induced accumulation of cAMP. The affinity of NNC 38-1049 for a number of variants of the histamine receptor was also determined. Following single dosing of normal rats with NNC 38-1049, hypothalamic histamine levels were assessed by means of microdialysis. Plasma and brain levels of NNC 38-1049 and acute effects on food intake and energy expenditure were followed after oral doses of 3–60 mg/kg. Potential side effects were examined with rat models of behaviour satiety sequence (BSS), pica behaviour and conditioned taste aversion (CTA). Intakes of food and water together with body weight were recorded for 15 days during daily dosing of dietary obese rats.RESULTS:NNC 38-1049 was found to be a highly specific and competitive antagonist towards both human and rat histamine H3 receptors, and measurable amounts of NNC 38-1049 were found in the plasma of rats following single oral doses of 3–60 mg/kg and in the brain after 15–60 mg/kg. Following single intraperitoneal injections of NNC 38-1049 (20 mg/kg), significant increases in extracellular histamine concentrations were observed. The same dose did not change BSS or pica behaviour acutely, nor did it induce CTA following repeated administration for 7 days. Reductions in food intake were seen very soon after administration, and occurred in a dose-dependent fashion. Energy expenditure was unchanged, but the respiratory quotient (RQ) tended to decrease at higher doses, indicating an increase in lipid oxidation. Twice daily administration of 20 mg/kg of NNC 38-1049 in old and dietary obese rats resulted in sustained reduction of food intake throughout a 2-week study, and was associated with a highly significant (P<0.01) decrease in body weight compared with controls (−18.4±3.4 vs +0.4±2.7 g). The same dose of NNC 38-1049 produced an acute decrease of water intake, but 24 h intakes were not significantly changed.CONCLUSIONS:The results of this study strongly support the idea that an increase in the hypothalamic concentration of histamine produces a specific reduction of food intake and that this effect can be translated into a decrease in body weight.International Journal of Obesity (2005) 29, 1402–1412. doi:10.1038/sj.ijo.0803036; published online 6 September 2005 [ABSTRACT FROM AUTHOR] more...
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- 2005
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14. Optimisation of the treatment technique used for the conjunctival lymphoma by means of Monte Carlo simulations and dose volume histograms on high resolution CT images
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Lorenzo Brualla, Zaragoza, F. J., Sempau, J., Wittig, A., and Sauerwein, W.
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Medizin
15. RECOGNITION OF THE 117-125 PEPTIDE OF THE HSP60 FROM Klebsiella pneumoniae BY CD8 T CELLS FROM ANKYLOSING SPONDYLITIS PATIENTS.
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Zambrano-Zaragoza, F., González-Juárez, D., Burgos-Vargas, R., Domínguez-López, L., Cancino-Díaz, M., Jiménez-Zamudio, L., and García-Latorre, E.
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PEPTIDES , *KLEBSIELLA pneumoniae , *T cells , *ANKYLOSING spondylitis , *LYMPHOCYTES , *PATIENTS - Abstract
Ankylosing spondylitis (AS) is a chronic inflammatory disease of unknown etiology but associated with HLA-B27. In our laboratory we have previously reported that AS patients show lymphoproliferative response to the HSP60 from Klebsiella pneumoniae. On the other hand, we have also reported in the HSP60 sequence a nonapeptide (residues 117-125) that have high affinity for B2705. In order to know the role of this nonapeptide in AS, we separated by inmunomagnetics beads CD4 and CD8 T lymphocytes from PBMC of AS B27+ patients and healthy subjects. Subpopulations were analyzed by flow cytometry to verify purity. CD4 T lymphocytes were sensitized with 6 micrograms of peptide for 24 hours in AIM-V medium at 37°C in a CO2 atmosphere. Afterwards these cells were washed and adjusted to be use as target cells. CD8 T lymphocytes were used as effectors cells. Target and effectors cells were mixed in a 1:1 ratio, in a final volume of 200 microliters in AIM-V medium and incubated 24 hours at 37°C in CO2 atmosphere. Then 20 microliters of alamar blue were added and incubated 24 hours more in the same conditions. Flourescence was determined and % of dead target cells was calculated. In all subjects analyzed, subpopulations purity was up to 95%. 5/10 AS patients and 0/6 healthy subjects showed citotoxic activity, suggesting that the 117-125 peptide could be a target for CD8 T lymphocytes in B27 positive AS patients. [ABSTRACT FROM AUTHOR] more...
- Published
- 2002
16. Reefscape proxies for the conservation of Caribbean coral reef biodiversity.
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Arias-González, J. E., Núñez-Lara, E., Rodríguez-Zaragoza, F. A., and Legendre, P.
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MARINE species diversity , *MARINE biodiversity , *CORALS , *FISHES , *CORAL reefs & islands - Abstract
The explanatory value of four hypotheses for geographic variation in total species richness and species richness was evaluated per family in coral and fish communities in the North Sector of the Mesoamerican Barrier Reef System (NS-MBRS). The four hypotheses emphasize different reefscape attributes that are important for coral and fish: reef area (RA), live coral cover (LCC), habitat complexity (HC), and coral richness itself and for fish. For both coral and fish communities, we estimated the total number of species and number of species per family on 11 coral reefs along a 400-km section of NS-MBRS. Hard coral cover and HC were quantified using line and chain transects, respectively, and RA was estimated using Landsat TM images and a geographic information system. We used multiple regression and canonical redundancy analysis to study the fish-environment and coral-environment relationships. The three reefscape features (RA, LCC, and HC) in combination were much stronger explanatory variables for the observed biogeographic patterns of fish and coral biodiversity than they were singly. Coral and fish species richness were strongly correlated. Indicators of functional diversity (fish trophic groups and coral morphofunctional groups) followed the same biogeographic patterns as species richness. Reefscape attributes (RA, LCC, and HC) were shown to be good proxies for critical coral reef biodiversity values. This means that simple reefscape attributes can be used to predict more complex biodiversity values of different reef areas. Such predictions can provide an invaluable guide for regional biodiversity assessments, the extrapolation of these results to unsurveyed areas, and guidance for ecoregionalization within large reef tracts where data are sparse. [ABSTRACT FROM AUTHOR] more...
- Published
- 2011
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17. Indicadores del paisaje arrecifal para la conservación de la biodiversidad de los arrecifes de coral del Caribe.
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Arias-González, J. E., Núñez-Lara, E., Rodríguez-Zaragoza, F. A., and Legendre, P.
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MARINE species diversity , *MARINE biodiversity , *CORALS , *FISHES , *CORAL reefs & islands - Abstract
Se evaluó el valor explicativo de cuatro hipótesis en la variación geográfica de la riqueza total de especies y la riqueza de especies por familia en comunidades de corales y peces en el Sector Norte del Sistema Arrecifal Mesoamericano (NS-MBRS). Las cuatro hipótesis ponderan diferentes atributos de paisaje que son importantes para las especies de corales y peces: área de arrecife (RA), cobertura de coral vivo (LCC), complejidad de hábitat (HC), y riqueza de coral para los peces y los corales mismos. Tanto para las comunidades de coral como para las de peces, se estimó el número total de especies y el número de especies por familia en 11 arrecifes coralinos a lo largo de una sección de 400 km del NS-MBRS. La cobertura de corales duros y HC fueron cuantificadas usando videotransectos de línea y cadena, respectivamente; RA se estimó usando imágenes de satélite TM Landsat y un sistema de información geográfica. Se utilizó el análisis de regresion múltiple y el análisis de redundancia canónica para estudiar las relaciones de las especies de coral y de peces con las variables estudiadas. Los tres atributos de paisaje (RA, LCC y HC) en combinación fueron variables explicativas mucho más importantes para los patrones biogeográficos observados de la biodiversidad de peces y corales que la explicación individual de cada una de las variables. La riqueza de especies de coral y de peces estuvieron también fuertemente correlacionadas. Los indicadores de la diversidad funcional (grupos tróficos de peces y los grupos morfofuncionales de corales) siguieron los mismos patrones biogeográficos que la riqueza de especies. Los atributos de paisaje (RA, LCC y HC) mostraron ser excelentes indicadores de valores críticos de biodiversidad coralina. Esto significa que los simples atributos de paisaje pueden ser usados para predecir valores de biodiversidad más complejos en diferentes áreas de arrecifes coralinos. Tales predicciones pueden proporcionar una guía inestimable para las evaluaciones de biodiversidad regional, la extrapolación de estos resultados a áreas no muestreadas y una guía para la ecoregionalización dentro de grandes extensiones de áreas de arrecifes coralinos donde los datos son escasos. [ABSTRACT FROM AUTHOR] more...
- Published
- 2011
18. Mindfulness-based interventions for improving mental health of frontline healthcare professionals during the COVID-19 pandemic: a systematic review.
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Benavides-Gil G, Martínez-Zaragoza F, Fernández-Castro J, Sánchez-Pérez A, and García-Sierra R
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- Humans, SARS-CoV-2, Burnout, Professional prevention & control, Pandemics, Mindfulness methods, COVID-19 psychology, COVID-19 epidemiology, Health Personnel psychology, Mental Health
- Abstract
Background: Mindfulness-based interventions (MBIs) appear to be effective for improving the mental health of healthcare professionals (HCPs). However, the effectiveness of MBIs on extreme psychological trauma caused by the coronavirus disease 2019 (COVID-19) pandemic is largely unknown. The aim of this paper was to systematically review empirical studies of MBIs for HCPs carried out during the COVID-19 pandemic, to evaluate them and their effectiveness in different areas of mental health., Methods: The electronic databases searched were Web of Science, Scopus, PubMed, and PsycINFO. The date when each database was last searched was September 15, 2023. Randomized controlled trials (RCTs), non-randomized controlled trials (NRCTs), and non-randomized non-controlled trials (NRNCTs) focused on MBIs for health care staff who were working in healthcare centers during the COVID-19 pandemic were included. All of them employed standardized measures of mental health. The review followed the best practices and reported using PRISMA guidelines. A data collection form, adapted from the Cochrane handbook for systematic reviews of interventions, was used to extract and synthesize the results. The methods used to assess the risk of bias in the included studies were the Cochrane Risk of Bias Tool and the ROBINS-I Tool., Results: Twenty-eight studies were included in the systematic review. Overall, the methodological quality of the studies was moderate. The results showed the effectiveness of MBIs in improving levels of stress, mindfulness, and mental well-being. However, no conclusive results were found regarding the effectiveness of MBIs in improving the levels of burnout, anxiety, depression, sleep quality, and resilience of HCPs., Conclusions: The MBIs for HCPs carried out during the COVID-19 pandemic have mainly contributed to improving stress, mindfulness, and mental well-being at a time of serious health emergency. However, more robust studies at a methodological level would have been desirable., Systematic Review Registration: PROSPERO CRD42021267621., (© 2024. The Author(s).) more...
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- 2024
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19. Effects of a mindfulness-based program on the occupational balance and mental health of university students. Protocol for a randomized controlled trial.
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Lillo-Navarro C, Fernández-Pires P, Benavides Gil G, Martínez-Zaragoza F, Chaves C, Roca P, Peral-Gómez P, González Valero ME, Mendialdua Canales D, Poveda Alfaro JL, Goldin PR, and Sánchez-Pérez A
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- Adult, Female, Humans, Male, Young Adult, Meditation methods, Meditation psychology, Surveys and Questionnaires, Universities, Virtual Reality, Randomized Controlled Trials as Topic, Mental Health, Mindfulness methods, Students psychology
- Abstract
Objective: The aim is to examine whether the addition of Virtual Reality (VR) meditation training to a standard 8-week Mindfulness-Based Health Care Program (MBHC-VR) results in a significantly increased improvement in occupational, mental health, and psychological functioning versus MBHC-only in university students., Materials and Methods: A randomized controlled clinical trial with three arms (MBHC, MBHC-VR, Control Group), four assessment time points (pre-intervention, inter-session, post-intervention, and 3-month follow-up), and mixed methodology will be proposed. University students (undergraduate, master, or doctoral) interested in participating and who meet the inclusion/exclusion criteria will be included over two years. Data will be collected from different ad hoc questionnaires, several standardized tests, and an Ecological Momentary Assessment. We will use R software to carry out descriptive analyses (univariate and bivariate), multilevel modeling, and structural equation models to respond to the proposed objective. The qualitative analysis will be carried out using the MAXQDA program and the technique of focus groups., Discussion: It is expected that with the proposed intervention university students will learn to relate in a healthier way with their mental processes, so as to improve their occupational balance (OB) and their psychological well-being., Trial Registration: ClinicalTrials.gov Identifier NCT05929430., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2024 Lillo-Navarro et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.) more...
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- 2024
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20. Pain-Related Worrying and Goal Preferences Determine Walking Persistence in Women with Fibromyalgia.
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Pastor-Mira MÁ, López-Roig S, Toribio E, Martínez-Zaragoza F, Nardi-Rodríguez A, and Peñacoba C
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- Cross-Sectional Studies, Female, Goals, Humans, Pain, Walking, Fibromyalgia
- Abstract
Physical activity and exercise are relevant behaviors for fibromyalgia health outcomes; however, patients have difficulties undertaking and maintaining an active lifestyle. With a cross-sectional design, this study explored the role of pain-related worrying and goal preferences in the walking persistence of women with fibromyalgia. The sample included 111 women who attended a tertiary health setting. We adapted the Six-Minute Walk Test where participants decided either to stop or continue walking in five voluntary 6 min bouts. Women who were categorized higher in pain-related worrying reported higher preference for pain avoidance goals ( t = -2.44, p = 0.02) and performed worse in the walking task (LongRank = 4.21; p = 0.04). Pain avoidance goal preference increased the likelihood of stopping after the first ( OR = 1.443), second ( OR = 1.493), and third ( OR = 1.540) 6 min walking bout, and the risk of ending the walking activity during the 30 min task ( HR = 1.02, [1.0-1.03]). Influence of pain-related worrying on total walking distance was mediated by goal preferences ( ab = -3.25). In interventions targeting adherence in physical activity and exercise, special attention is needed for women who are particularly worried about pain to help decrease their preference for short-term pain avoidance goals relative to long-term goals such as being active through walking. more...
- Published
- 2022
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21. Predicting Abusive Behaviours in Spanish Adolescents' Relationships: Insights from the Reasoned Action Approach.
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Nardi-Rodríguez A, Pastor-Mira MÁ, López-Roig S, Pamies-Aubalat L, Martínez-Zaragoza F, and Ferrer-Pérez VA
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- Adolescent, Cross-Sectional Studies, Female, Humans, Intention, Male, Surveys and Questionnaires, Adolescent Behavior, Aggression
- Abstract
(1) Background: Partner violence prevention programmes do not produce the expected behavioural changes. Accordingly, experts suggest applying evidence-based behavioural models to identify the determinants of abusive behaviours. In this research, we applied the reasoned action approach (RAA) to predict the performance (boys) and acceptance (girls) of abusive behaviours in adolescents. (2) Method: We designed a questionnaire based on the RAA and performed a cross-sectional study. We analysed the predictive capacity of the RAA constructs on intentions with the sample of single adolescents ( n = 1112). We replicated the analysis only with those who were in a relationship ( n = 587) and in addition analysed the predictive capacity of intention on future behaviour (3 months later). (3) Results: The hierarchical regression analysis performed with the sample of single adolescents showed that the model explained 56% and 47% of the variance of boys' intentions to perform the controlling and devaluing behaviours, respectively; and 62% and 33% of girls' intention to accept them. With those in a relationship, the model explained 60% and 53% of the variance of boys' intentions to perform the controlling and devaluating behaviour, respectively, and 70% and 38% of girls' intention to accept them. Intention exerted direct effects on boys' performance of controlling and devaluing behaviours (31% and 34% of explained variance, respectively) and on girls' acceptance (30% and 7%, respectively). (4) Conclusions: The RAA seems useful to identify the motivational determinants of abusive behaviours, regardless of adolescents´ relationship status, and for their prediction. Perceived social norms emerge as a relevant predictor on which to intervene to produce behavioural changes with both sexes. more...
- Published
- 2022
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22. Motivational Determinants of Objective Physical Activity in Women with Fibromyalgia Who Attended Rehabilitation Settings.
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Pastor-Mira MÁ, López-Roig S, Martínez-Zaragoza F, Toribio E, Nardi-Rodríguez A, and Peñacoba C
- Abstract
Being physically active has positive effects on fibromyalgia functioning. However, promoting an active lifestyle in these patients continues to be a relevant clinical challenge. Our aim was to test a motivational model to explain light (LPA) and moderate-vigorous physical activity (MVPA). A cross-sectional prospective study was conducted at a tertiary level of care. Participants completed sociodemographic, clinical, motivational (physical activity self-efficacy and goal preferences) and behavioral measures (activity avoidance). LPA and MVPA were measured with triaxial accelerometers, starting the same day of the aforementioned assessment. Out of 211 women, 183 completed this measure. Structural models were performed. Our results show that the best fit indices (CFI = 0.97, SRMR = 0.04) showed a model with direct influence of PA self-efficacy on MVPA ( p < 0.01) and indirect influence on LPA ( p < 0.001). LPA received the influence of PA self-efficacy mainly through activity avoidance ( p < 0.01). Clinical variables did not have any effect on PA intensities. Thus, the motivational variables showed different paths to explain two PA intensities. Targeting PA self-efficacy in rehabilitation settings is needed to enhance both daily LPA and MVPA intensities. more...
- Published
- 2021
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23. When and how do hospital nurses cope with daily stressors? A multilevel study.
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Martínez-Zaragoza F, Benavides-Gil G, Rovira T, Martín-Del-Río B, Edo S, García-Sierra R, Solanes-Puchol Á, and Fernández-Castro J
- Subjects
- Adaptation, Psychological, Adult, Affect, Female, Humans, Male, Middle Aged, Multilevel Analysis, Social Support, Nurses psychology, Occupational Stress therapy
- Abstract
Background: During their workday, nurses face a variety of stressors that are dealt with using different coping strategies. One criticism of the contextual models of work stress is that they fail to focus on individual responses like coping with stress. Neverthless, little is know about the momentary determinants of coping in nurses., Objectives: To identify the momentary predictors of problem-focused approaching coping and emotion-focused approaching coping, as well as those for seeking social support and refusal coping strategies, during the working day in nurses., Design: This study uses descriptive, correlational, two-level design with repeated measures., Settings: Wards of two University hospitals., Participants: A random cohort of 113 nurses was studied., Methods: An ecological momentary assessment was made of demand, control, effort, reward, nursing task, coping, mood and fatigue, and of coping style by questionnaire. Multilevel two-level statistical analyses were performed in order to identify both within person and between person relationships., Results: Different momentary types of coping were associated with different tasks. The problem-focused coping could be explained by the direct care and medication tasks, demand, planning coping style, mood, and negatively by acceptation coping style. Emotion-focused coping could be explained by documentation and medication tasks (negatively), mood, demand, distraction, and disengagement coping styles. Seeking social support coping could be explained by the task of communication, mood, fatigue (negatively), and seeking emotional support as a coping style. Refusal coping could be explained by mood, and the coping style of focusing and venting emotions. Refusal coping is not specific to any task., Conclusions: The choice of the coping strategy depends on the task, of their appraisal and on the different styles of coping., Competing Interests: The authors have declared that no competing interests exist. more...
- Published
- 2020
- Full Text
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24. How the Lagged and Accumulated Effects of Stress, Coping, and Tasks Affect Mood and Fatigue during Nurses' Shifts.
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Martínez-Zaragoza F, Fernández-Castro J, Benavides-Gil G, and García-Sierra R
- Subjects
- Affect, Fatigue, Humans, Surveys and Questionnaires, Workload, Adaptation, Psychological, Burnout, Professional, Nursing
- Abstract
Nurses experience significant stress and emotional exhaustion, leading to burnout and fatigue. This study assessed how the nurses' mood and fatigue evolves during their shifts, and the temporal factors that influence these phenomena. Performing a two-level design with repeated measures with moments nested into a person level, a random sample of 96 nurses was recruited. The ecological momentary assessment of demand, control, effort, reward, coping, and nursing tasks were measured in order to predict mood and fatigue, studying their current, lagged, and accumulated effects. The results show that: (1) Mood appeared to be explained by effort, by the negative lagged effect of reward, and by the accumulated effort, each following a quadratic trend, and it was influenced by previously executing a direct care task. By contrast, fatigue was explained by the current and lagged effect of effort, by the lagged effect of reward, and by the accumulated effort, again following quadratic trends. (2) Mood was also explained by problem-focused and emotion-focused coping strategies, indicative of negative mood, and by support-seeking and refusal coping strategies. (3) Fatigue was also associated with direct care and the prior effect of documentation and communication tasks. We can conclude that mood and fatigue do not depend on a single factor, such as workload, but rather on the evolution and distribution of the nursing tasks, as well as on the stress during a shift and how it is handled. The evening and night shifts seem to provoke more fatigue than the other work shifts when approaching the last third of the shift. These data show the need to plan the tasks within a shift to avoid unfinished or delayed care during the shift, and to minimize accumulated negative effects. more...
- Published
- 2020
- Full Text
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25. Goal Preferences, Affect, Activity Patterns and Health Outcomes in Women With Fibromyalgia.
- Author
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Pastor-Mira MA, López-Roig S, Martínez-Zaragoza F, León E, Abad E, Lledó A, and Peñacoba C
- Abstract
Some motivational models understand health behavior as a result of the interaction between goal preferences and mood. However, this perspective has not been explored in fibromyalgia. Furthermore, in chronic pain, it has only been explored with regard to negative affect. Thus, our aims were: (1) to develop a Spanish version of the Goal Pursuit Questionnaire (GPQ); (2) to explore the relationships between goal preferences and health outcomes, testing the moderator role of affect and the mediating role of chronic pain activity patterns. We conducted two cross-sectional studies. In Study 1, after a double translation/back-translation process, we interviewed 94 women attending the Fibromyalgia Unit of the Community of Valencia in order to identify the cultural feasibility and the content validity of the GPQ. Study 2 comprised 260 women. We explored the GPQ structure and performed path analyses to test conditional mediation relationships. Eight activities from the original GPQ were changed while maintaining the conceptual equivalence. Exploratory factor analysis showed two factors: 'Pain-avoidance goal' and 'Mood-management goal' (37 and 13% of explained variance, respectively). These factors refer to patients' preference for hedonic goals (pain avoidance or mood-management) over achievement goals. Robust RMSEA fit index of the final models ranged from 0.039 for pain to 0.000 for disability and fibromyalgia impact. Pain avoidance goals and negative affect influenced pain mediated by task-contingent persistence. They also affected disability mediated by task and excessive persistence. Pain avoidance goals and positive affect influenced fibromyalgia impact mediated by activity avoidance. We also found a direct effect of negative and positive affect on health outcomes. Preference for pain avoidance goals was always related to pain, disability and fibromyalgia impact through activity patterns. Affect did not moderate these relationships and showed direct and indirect paths on health outcomes, mainly by increasing persistence and showing positive affect as an asset and not a risk factor. Intervention targets should include flexible reinforcement of achievement goals relative to pain avoidance goals and positive affect in order to promote task-persistence adaptive activity patterns and decreased activity avoidance. more...
- Published
- 2019
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26. Personality and psychopathology in potential live kidney donors: A cluster analysis of personality features.
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Leal-Costa C, Ramos-Morcillo AJ, Martínez Zaragoza F, Bernabeu Juan P, Rodríguez-Marín J, Ruzafa-Martínez M, and van-der Hofstadt Román CJ
- Subjects
- Adult, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Kidney Transplantation psychology, Living Donors psychology, Personality
- Abstract
Background: The previous psychosocial evaluation of the potential living kidney donors (PLKD) requires a detailed understanding of the psychosocial benefits and the possible damages of the act of donation., Objective: The aim was to create clusters by using the clinical patterns of personality and to evaluate their influence on psychopathological variables., Methods: Observational, analytical and cross-sectional study that included the PLKD from February 2009 to March 2017. The patients were referred to the Hospital Psychology Unit by the Transplant Coordination Unit. The total sample was composed of 100 participants. The socio-demographic characteristics, the relationship with the recipient and the Millon Clinical Multiaxial Inventory were included., Results: The final sample was composed by 100 PLKD. The mean age of the participants was 45.70, and most were women (70%). The analysis showed a final result of 3 personality clusters that best represented the data, in agreement with the DSM-5 classification. The PLKD from cluster 3 obtained greater scores in all the clinical syndromes., Conclusions: The personality evaluation of the PLKD could help with the planning of monitoring protocols of the participants who were classified to cluster 3, in order to improve their post-transplant psychosocial adjustment. This result makes us consider the usefulness of the psychosocial evaluation to preserve the psychological health of the PLKD., Competing Interests: The authors have declared that no competing interests exist. more...
- Published
- 2019
- Full Text
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27. One-Step Conversion of Methyl Ketones to Acyl Chlorides.
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Zaragoza F
- Abstract
Treatment of aromatic and heteroaromatic methyl ketones with sulfur monochloride and catalytic amounts of pyridine in refluxing chlorobenzene leads to the formation of acyl chlorides. Both electron-rich and electron-poor aryl methyl ketones can be used as starting materials. The resulting C1-byproduct depends on the precise reaction conditions chosen. more...
- Published
- 2015
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28. Control Strategy Scenarios for the Alien Lionfish Pterois volitans in Chinchorro Bank (Mexican Caribbean): Based on Semi-Quantitative Loop Analysis.
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Ortiz M, Rodriguez-Zaragoza F, Hermosillo-Nuñez B, and Jordán F
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- Animals, Caribbean Region, Humans, Mexico, Models, Theoretical, Population Control, Population Dynamics, Introduced Species, Perciformes
- Abstract
Ecological and eco-social network models were constructed with different levels of complexity in order to represent and evaluate management strategies for controlling the alien species Pterois volitans in Chinchorro bank (Mexican Caribbean). Levins´s loop analysis was used as a methodological framework for assessing the local stability (considered as a component of sustainability) of the modeled management interventions represented by various scenarios. The results provided by models of different complexity (models 1 through 4) showed that a reduction of coral species cover would drive the system to unstable states. In the absence of the alien lionfish, the simultaneous fishing of large benthic epifaunal species, adult herbivorous fish and adult carnivorous fish could be sustainable only if the coral species present high levels of cover (models 2 and 3). Once the lionfish is added to the simulations (models 4 and 5), the analysis suggests that although the exploitation or removal of lionfish from shallow waters may be locally stable, it remains necessary to implement additional and concurrent human interventions that increase the holistic sustainability of the control strategy. The supplementary interventions would require the implementation of programs for: (1) the restoration of corals for increasing their cover, (2) the exploitation or removal of lionfish from deeper waters (decreasing the chance of source/sink meta-population dynamics) and (3) the implementation of bans and re-stocking programs for carnivorous fishes (such as grouper) that increase the predation and competition pressure on lionfish (i.e. biological control). An effective control management for the alien lionfish at Chinchorro bank should not be optimized for a single action plan: instead, we should investigate the concurrent implementation of multiple strategies. more...
- Published
- 2015
- Full Text
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29. Individual differences in personality profiles among potential living kidney transplant donors.
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van-der Hofstadt CJ, Rodríguez-Marín J, Martínez-Zaragoza F, and de Santiago-Guervós C
- Abstract
Background: Although the psychological assessment of potential living kidney donors (PLKD) is part of the recommendations for action for any transplant coordination, there are not many studies that provide data about the importance of selecting donors for improving transplant outcomes. This work aims to raise awareness of potential kidney donors by designing methods for early detection of potential problems after the transplant, as well as by selecting the most suitable donors., Methods: This is a study of 25 PLKD drawn from the General University Hospital of Alicante. Participants completed the Millon Clinical Multiaxial Inventory (MCMI-III) for the study of personality characteristics., Results: Women scored higher than men in the compulsive personality scale, and individuals with a genetic link with the recipient scored higher on depressive and dependent scales than did those with other relationships (emotional or altruistic)., Conclusions: Women showed a pattern of significantly more compulsive personality traits (cautious, controlled, perfectionist) within a non-pathological style. Among the PLKD, there were significantly more women, which is contrary to what typically happens with donations from cadavers. Genetically related subjects scored higher on depression than did those that were emotionally related. The personality assessment of candidates for PLKD can help with developing a post-transplant follow-up regimen for an improved quality of life. more...
- Published
- 2013
30. CD4 and CD8 T cell response to the rHSP60 from Klebsiella pneumoniae in peripheral blood mononuclear cells from patients with ankylosing spondylitis.
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Zambrano-Zaragoza F, García-Latorre E, Domínguez-López ML, Cancino-Díaz ME, Burgos-Vargas R, and Jiménez-Zamudio L
- Subjects
- Autoimmune Diseases blood, Autoimmune Diseases genetics, Brefeldin A pharmacology, CD4-Positive T-Lymphocytes drug effects, CD8-Positive T-Lymphocytes drug effects, Chloroquine pharmacology, Cytosol immunology, Endocytosis, Flow Cytometry, HLA-B27 Antigen analysis, HLA-B27 Antigen genetics, Humans, Klebsiella pneumoniae chemistry, Leukocytes, Mononuclear immunology, Leupeptins pharmacology, Spondylitis, Ankylosing blood, Spondylitis, Ankylosing genetics, T-Lymphocyte Subsets drug effects, Antigen Presentation drug effects, Antigens, Bacterial immunology, Autoimmune Diseases immunology, CD4-Positive T-Lymphocytes immunology, CD8-Positive T-Lymphocytes immunology, HLA-B27 Antigen immunology, Klebsiella pneumoniae immunology, Lymphocyte Activation drug effects, Spondylitis, Ankylosing immunology, T-Lymphocyte Subsets immunology
- Abstract
Objective: To determine the processing pathways used by peripheral blood mononuclear cells (PBMC) and present the rHSP60Kp, and the T cell subpopulations involved in the response, in patients with ankylosing spondylitis (AS) METHODS: The lymphoproliferative response to the rHSP60Kp in PBMC from 14 HLA-B27+ AS patients and 15 B27- healthy controls was assessed by 3H-TdR incorporation. The processing pathways for the rHSP60Kp were analyzed by 3H-TdR incorporation in fresh PBMC from patients using homologous PBMC preincubated with the antigen and specific inhibitors: chloroquine, N-acetyl-L-leucil-L-leucil-L-nor-leucinal (LLnL) or brefeldin A (BFA), fixed with p-formaldehyde (fixed APC). The CD4+/CD8+ T cell subpopulation activated with the antigen was determined by three colours flow cytometry in PBMC from patients., Results: Eight out of fourteen patients showed positive lymphoproliferative responses to the rHSP60Kp while none of the healthy controls responded (p < 0.012). In five patients S.I. was above 4.0. In these patients lymphoproliferation was lower when chloroquine and LLnL was used and it became negative with BFA, indicating that both pathways are used. CD4+ and CD8+ T cells populations expressed CD69 when activated by the rHSP60Kp., Conclusions: Our results suggest that CD4 and CD8 T cells participate in the response to the rHSP60Kp in B27+ AS patients. more...
- Published
- 2005
31. One-step conversion of alcohols into nitriles with simultaneous two-carbon chain elongation. (Cyanomethyl)trimethylphosphonium iodide as a reagent with a dual mode of action.
- Author
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Zaragoza F
- Abstract
Treatment of alcohols with an excess of (cyanomethyl)trimethylphosphonium iodide leads, after aqueous hydrolysis, to the clean formation of nitriles with two more carbon atoms than present in the original alcohol. Benzylic, allylic, and aliphatic alcohols without beta-branching (RCH(2)CH(2)OH) have been converted to nitriles with success. The required phosphonium iodide is simple to prepare and can be stored for a long time at room temperature. more...
- Published
- 2002
- Full Text
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32. (Cyanomethyl)trialkylphosphonium iodides: efficient reagents for the intermolecular alkylation of amines with alcohols in solution and on solid phase.
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Zaragoza F and Stephensen H
- Published
- 2001
- Full Text
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33. Impact of oral immunization with Acanthamoeba antigens on parasite adhesion and corneal infection.
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Leher H, Kinoshita K, Alizadeh H, Zaragoza FL, He Y, and Niederkorn J
- Subjects
- Acanthamoeba Keratitis immunology, Administration, Oral, Animals, Cricetinae, Cricetulus, Enzyme-Linked Immunosorbent Assay, Epithelium, Corneal parasitology, Humans, Immunity, Mucosal, Intestinal Mucosa immunology, Swine, Tissue Adhesions immunology, Acanthamoeba immunology, Acanthamoeba Keratitis prevention & control, Antigens, Protozoan immunology, Immunization methods, Immunoglobulin A, Secretory immunology, Tears immunology
- Abstract
Purpose: To determine whether oral immunization mitigates ongoing Acanthamoeba castellanii corneal infections in pigs., Methods: Pigs were orally immunized with aqueous Acanthamoeba antigen mixed with cholera toxin (Ac-CT) or with saline, before or after ocular infection with A. castellanii. Mucosal secretions (i.e., tears and enteric wash) were tested for Acanthamoeba-specific IgA by enzyme-linked immunosorbent assay. Enteric washes were used as a source of IgA in assays measuring the binding of trophozoites to Chinese hamster corneal epithelial (CHCE) cells., Results: Pigs immunized with Ac-CT before ocular challenge with A. castellanii had significant anti-Acanthamoeba IgA antibody titers in their tears and enteric washes and were protected against ocular infection. Enteric washes from orally immunized pigs inhibited trophozoite binding to CHCE cells in vitro by more than 75%. By contrast, pigs immunized after corneal infections had been established displayed keratitis of the same severity and duration as that in control pigs. However, 80% of the orally immunized animals were resistant to rechallenge with Acanthamoeba-laden contact lenses, whereas none of the control animals was resistant., Conclusions: Oral immunization with Ac-CT protects against Acanthamoeba keratitis when administered before corneal challenge. However, delaying oral immunization until after corneal disease is established fails to mitigate keratitis. The appearance of parasite-specific tear IgA correlates with protection and may act by preventing the parasite's binding to the corneal epithelium. more...
- Published
- 1998
34. [Science and power, today and tomorrow].
- Author
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Mayor Zaragoza F
- Published
- 1997
- Full Text
- View/download PDF
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