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2. Charge Loss Correction in the Silicon-Tungsten Tracker-Converter for Proton-Helium Charge Identification in the DAMPE Detector

Author

Zi Qing Xia, F. C. T. Barbato, M. Di Santo, Kai Kai Duan, D. Mo, A. Ruina, A. Kotenko, Tao Ma, Yong Jie Zhang, Yan Fang Wang, M. N. Mazziotta, H. Su, Yong Qiang Zhang, A. Parenti, Guang Shun Huang, Z. X. Dong, Meng Su, Hui Jun Yao, Jinglai Duan, Xiao Yuan Huang, Yang Haibo, X. J. Teng, Qi Ding, F. de Palma, J. N. Rao, Chang Yi Zhou, Zhi Yong Zhang, J. J. Zang, Lei Feng, Chang Qing Feng, Hao Ran Sun, J. J. Wei, Lihui Wu, Huaguang Wang, Yi Zhang, Yao Ming Liang, Xu Pan, D. D'Urso, Zhan Fang Chen, Yan Zhang, Maria Ionica, Jie Kong, E. Casilli, W. H. Shen, Y. Y. Huang, Shi Jun Lei, Cong Zhao, L. Silveri, P. Fusco, A. De Benedittis, M. S. Cai, Deng Yi Chen, F. Alemanno, Peng Xiong Ma, Z. T. Shen, I. De Mitri, D. Droz, Yang Liu, Q. An, Xiao Yong Ma, W. X. Peng, M. Stolpovskiy, M. Y. Cui, Zi Zong Xu, Sheng Xia Zhang, Jin Zhou Wang, K. Gong, Yi-Zhong Fan, Xiang Li, Hong Yun Zhao, M. M. Salinas, Xiao Yang Niu, Ya Peng Zhang, R. Qiao, Z. Y. Sun, G. Z. Shang, Shuang Xue Han, E. Catanzani, Shu Xin Wang, Wen Hao Li, Peng Yang, Di Wu, En Heng Xu, T. S. Cui, A. Surdo, Jian Wu, Jin Chang, P. Azzarello, Chuan Yue, Ya Qing Yang, Shen Wang, Xin Wu, Fang Fang, Kun Fang, Chuan Ning Luo, Maksym Deliyergiyev, F. Gargano, Jian Hua Guo, D. Kyratzis, Y. Z. Gong, Qiang Yuan, X. Y. Peng, S. B. Liu, Xian Qiang Li, M. M. Ma, Y. F. Wei, Y. H. Yu, Yun Long Zhang, C. Liu, Xiao Lian Wang, V. Gallo, W. Zhang, Wei Jiang, Zhe Zhang, C. Perrina, G. F. Xue, Ying Wang, Yu Xing Cui, Sha Sha Wu, Giacinto Donvito, Y. M. Hu, F. Loparco, J. L. Chen, Hao Ting Dai, L. G. Wang, Dong Ya Guo, Guan Wen Yuan, Hao Liu, Jie Liu, G. Marsella, Andrii Tykhonov, Hai Tao Xu, Xiao Jun Bi, Min Gao, Zun Lei Xu, Zhao Qiang Shen, Xun Feng Zhao, Zhi Hui Xu, Da Ming Wei, Wei Liang Li, P. Bernardini, Tie Kuang Dong, Jing Xing Song, R. R. Fan, and Yuan Zhu Wang

Subjects
Physics, Nuclear physics, chemistry, Proton, Physics::Instrumentation and Detectors, Dark matter, Detector, Gamma ray, chemistry.chemical_element, Particle, Charge (physics), Helium, Ion
Abstract

The DArk Matter Particle Explorer (DAMPE) is a satellite-borne experiment, in operation since 2015, aimed at studying high-energy gamma rays and cosmic nuclei fluxes. Of the various sub-detectors in the DAMPE payload, the Silicon-Tungsten tracKer-converter (STK) plays a significant role in the charge measurement of incoming ions. Depending on the angle of inclination of the impinging particle and its position of impact on these strips, the collected charge can spread between the strips which results in some fractional signal loss. The $\eta$ variable is used to identify this spread of charge across the strips and correct for the associated charge loss. This brings us closer to accurate determination of particle charge which is crucial for ensuring a good discrimination between particles. The $\eta$-correction is, therefore, expected to play an important role in the determination of heavy ions by the DAMPE detector. It has helped reduce the proton background for the helium identification in STK by a factor of 1.5 for MIP tracks. It has been sucessfully applied to carbon nuclei and its application to heavier nuclei is currently being studied.

Published
2021
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3. Performance of the DAMPE silicon-tungsten tracker during the first 5 years of in-orbit operations

Author

Peng Yang, Jinglai Duan, Xian Qiang Li, Zun Lei Xu, Zhi Yong Zhang, Xiang Li, Zhao Qiang Shen, Xun Feng Zhao, Yang Haibo, Z. X. Dong, M. M. Ma, J. N. Rao, X. J. Teng, Ying Wang, Yang Liu, Guan Wen Yuan, Jin Zhou Wang, Qi Ding, Zhi Hui Xu, Kai Kai Duan, Z. Y. Sun, G. Marsella, Yu Xing Cui, D. Mo, J. J. Zang, Andrii Tykhonov, Da Ming Wei, W. H. Shen, Qiang Yuan, Giacinto Donvito, Y. H. Yu, Yun Long Zhang, P. Azzarello, Huaguang Wang, I. Di Santo, M. S. Cai, Hai Tao Xu, Yan Fang Wang, Di Wu, Chuan Ning Luo, Q. An, Wei Liang Li, S. B. Liu, Z. T. Shen, Xiao Jun Bi, Min Gao, A. Kotenko, Guang Shun Huang, Xiao Yuan Huang, Tie Kuang Dong, Jian Wu, Sha Sha Wu, W. X. Peng, Zhan Fang Chen, T. S. Cui, Ya Qing Yang, Tao Ma, Fang Fang, Jing Xing Song, K. Gong, Zi Zong Xu, R. R. Fan, F. de Palma, Yong Jie Zhang, Jian Hua Guo, Y. F. Wei, Maria Munoz Salinas, F. Loparco, Yan Zhang, M. N. Mazziotta, H. Su, En Heng Xu, C. Liu, Xiao Lian Wang, A. Surdo, Yi Zhang, J. L. Chen, G. Z. Shang, Shuang Xue Han, Chang Qing Feng, W. Zhang, Y. Z. Gong, Ya Peng Zhang, I. De Mitri, Lei Feng, Wei Jiang, Xiao Yong Ma, R. Qiao, Shu Xin Wang, Deng Yi Chen, Zhe Zhang, Li Bo Wu, Xiao Yang Niu, G. F. Xue, X. Y. Peng, Zi Qing Xia, D. Droz, F. Alemanno, Jin Chang, Yao Ming Liang, E. Catanzani, Wen Hao Li, Xin Wu, L. Silveri, Chang Yi Zhou, Yuan Zhu Wang, F. C. T. Barbato, F. Gargano, Chuan Yue, Yong Qiang Zhang, Yi-Zhong Fan, Meng Su, D. D'Urso, Dampe, Y. Y. Huang, Kun Fang, Maksym Deliyergiyev, P. Fusco, Shi Jun Lei, D. Kyratzis, A. De Benedittis, Peng Xiong Ma, P. Bernardini, A. Parenti, M. Stolpovskiy, M. Y. Cui, A. Ruina, Hui Jun Yao, Hao Ran Sun, J. J. Wei, Shen Wang, Hong Yun Zhao, Maria Ionica, Jie Kong, E. Casilli, Sheng Xia Zhang, Y. M. Hu, Hao Ting Dai, C. Perrina, L. G. Wang, Dong Ya Guo, Hao Liu, Jie Liu, Xu Pan, and Cong Zhao

Subjects
Physics, Optics, Physics::Instrumentation and Detectors, business.industry, Detector, Orbit (dynamics), Calibration, Satellite, Tracking (particle physics), business, Particle detector, Noise (radio), Charged particle
Abstract

Since its launch, in December 2015, the satellite-based DAMPE (DArk Matter Particle Explorer) particle detector is taking data smoothly. The Silicon-Tungsten tracKer-converter (STK) of DAMPE consists of six tracking planes (6x, 6y) of single-sided silicon micro-strip detectors mounted on seven support trays. The STK is able to measure the charge and precisely reconstruct the track of traversing charged particles. Tungsten plates (1 mm thick) are integrated in the second, third and fourth tray from the top to serve as $\gamma \rightarrow e^+e^−$ converters. Commissioned rapidly after the launch, the STK is running extremely well since then. The STK in-orbit calibration and performance during its first more than 5 years of operation, including the noise behaviour and the thermal and mechanical stability, are presented in this contribution.

Published
2021
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4. On-orbit performance of the DAMPE BGO calorimeter

Author

D. Droz, Yang Liu, Jin Zhou Wang, Guan Wen Yuan, G. Marsella, Zun Lei Xu, Zhao Qiang Shen, Xun Feng Zhao, Zhi Hui Xu, Ya Peng Zhang, Qiang Yuan, S. B. Liu, Andrii Tykhonov, Hai Tao Xu, Y. M. Hu, Xiao Jun Bi, Min Gao, K. Gong, Da Ming Wei, Yi Zhang, Chuan Yue, G. Z. Shang, Shuang Xue Han, Hao Ting Dai, Y. F. Wei, Shu Xin Wang, Jinglai Duan, Chang Qing Feng, Maria Ionica, Jie Kong, E. Casilli, Zi Qing Xia, Z. X. Dong, Wei Liang Li, P. Azzarello, M. Di Santo, Yao Ming Liang, Fang Fang, Yuan Zhu Wang, Y. Y. Huang, F. C. T. Barbato, Tie Kuang Dong, Peng Xiong Ma, P. Fusco, L. Silveri, J. J. Zang, Huaguang Wang, L. G. Wang, X. J. Teng, M. Y. Cui, Sha Sha Wu, C. Liu, Xiao Lian Wang, V. Gallo, W. Zhang, Dong Ya Guo, Yi-Zhong Fan, Tao Ma, Chuan Ning Luo, F. Loparco, Jing Xing Song, W. H. Shen, R. R. Fan, Yong Jie Zhang, M. S. Cai, Shen Wang, J. L. Chen, Hao Liu, Deng Yi Chen, J. N. Rao, M. N. Mazziotta, H. Su, Jie Liu, Yan Zhang, Z. T. Shen, Hui Jun Yao, Yifeng Wei, Y. H. Yu, P. Bernardini, W. X. Peng, Yun Long Zhang, A. Parenti, Wei Jiang, Yong Qiang Zhang, Meng Su, Kai Kai Duan, Zhe Zhang, D. Mo, F. Alemanno, Hao Ran Sun, Xiao Yang Niu, Peng Yang, Zhan Fang Chen, A. Ruina, J. J. Wei, Lihui Wu, Ying Wang, Xiao Yuan Huang, Yan Fang Wang, G. F. Xue, Sheng Xia Zhang, Di Wu, F. de Palma, Kun Fang, Zi Zong Xu, Chang Yi Zhou, Xin Wu, Yu Xing Cui, D. D'Urso, C. Perrina, D. Kyratzis, Yang Haibo, Q. An, Xian Qiang Li, Jian Wu, En Heng Xu, Shi Jun Lei, M. M. Ma, Jian Hua Guo, Qi Ding, Xu Pan, Giacinto Donvito, Ya Qing Yang, Jin Chang, Z. Y. Sun, R. Qiao, Cong Zhao, F. Gargano, I. De Mitri, Hong Yun Zhao, T. S. Cui, Xiao Yong Ma, Zhi Yong Zhang, E. Catanzani, Y. Z. Gong, Wen Hao Li, A. Surdo, X. Y. Peng, Dampe, M. M. Salinas, Guang Shun Huang, Lei Feng, A. De Benedittis, M. Stolpovskiy, A. Kotenko, and Xiang Li

Subjects
Physics, Scintillation, Range (particle radiation), Calorimeter (particle physics), Physics::Instrumentation and Detectors, Payload, business.industry, Detector, Dark matter, Optics, High Energy Physics::Experiment, Satellite, Optical filter, business
Abstract

The DArk Matter Particle Explorer (DAMPE) is the first Chinese cosmic-ray direct detection experiment. It has been operating smoothly on-orbit since its successful launch at the end of 2015. Currently, its sub-detectors and the satellite are in good working order. The DAMPE payload employs a BGO Calorimeter for energy measurements, trigger and e/p identification. The calorimeter is constructed of 308 BGO crystals, and PMTs are coupled to the crystals with optical filters to readout scintillation light. In this work, we present the status and performance of the calorimeter, including status of detector units, energy measurement, especially in TeV range, detector endurance, and long term performance in a duration of 65 months.

Published
2021
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5. Analyzing the Fermi Bubbles with DArk Matter Particle Explorer

Author

Z. X. Dong, J. N. Rao, D. Droz, Yang Liu, Jin Zhou Wang, Xun Feng Zhao, Zhi Hui Xu, Da Ming Wei, Yong Qiang Zhang, Meng Su, Zhan Fang Chen, Yuan Zhu Wang, Wei Liang Li, F. Alemanno, Yan Zhang, Yi Zhang, P. Azzarello, Guang Shun Huang, Tie Kuang Dong, Sha Sha Wu, A. Surdo, Jinglai Duan, Zhao-Qiang Shen, F. Loparco, J. L. Chen, Zi Qing Xia, I. De Mitri, Xiao Yong Ma, Zhi Yong Zhang, P. Bernardini, Jing Xing Song, F. C. T. Barbato, R. R. Fan, Z. Y. Sun, Yong Jie Zhang, Di Wu, Yang Haibo, Shi Jun Lei, Chuan Ning Luo, Y. H. Yu, Yun Long Zhang, Y. M. Hu, C. Liu, Xiao Lian Wang, M. N. Mazziotta, H. Su, K. Gong, Jian Wu, E. Catanzani, V. Gallo, W. Zhang, Wen Hao Li, Qi Ding, Ya Qing Yang, T. S. Cui, G. Z. Shang, Shuang Xue Han, Wei Jiang, Zhe Zhang, Zi Zong Xu, Xiang Li, G. F. Xue, Shu Xin Wang, Guan Wen Yuan, Xian Qiang Li, M. M. Ma, Hao Ting Dai, Ying Wang, Tao Ma, D. Mo, Hong Yun Zhao, G. Marsella, Andrii Tykhonov, Hai Tao Xu, Xiao Jun Bi, Min Gao, Yu Xing Cui, Yao Ming Liang, L. Silveri, Giacinto Donvito, Yan Fang Wang, L. G. Wang, Jin Chang, F. Gargano, Y. F. Wei, M. M. Salinas, Dong Ya Guo, Y. Z. Gong, Xu Pan, Xin Wu, Hao Liu, Jie Liu, X. Y. Peng, Cong Zhao, M. S. Cai, Jian Hua Guo, A. Parenti, Deng Yi Chen, Chang Qing Feng, Peng Xiong Ma, W. X. Peng, Ya Peng Zhang, En Heng Xu, A. Ruina, M. Y. Cui, Chang Yi Zhou, D. D'Urso, C. Perrina, J. J. Zang, Huaguang Wang, I. Di Santo, Chuan Yue, Shen Wang, Z. Xu, A. De Benedittis, Kun Fang, Yi-Zhong Fan, Xiao Yuan Huang, Kai-Kai Duan, D. Kyratzis, F. de Palma, M. Stolpovskiy, Qiang Yuan, S. B. Liu, Y. Y. Huang, P. Fusco, Lei Feng, A. Kotenko, Li Bo Wu, Xiao Yang Niu, Fang Fang, X. J. Teng, W. H. Shen, Z. T. Shen, Q. An, R. Qiao, Hui Jun Yao, Hao Ran Sun, J. J. Wei, Maria Ionica, Jie Kong, E. Casilli, Sheng Xia Zhang, and Peng Yang

Subjects
Physics, Range (particle radiation), High energy particle, Photon, Astrophysics::High Energy Astrophysical Phenomena, Dark matter, Galactic Center, Cosmic ray, Astrophysics::Cosmology and Extragalactic Astrophysics, Astrophysics, Galactic plane, Astrophysics::Galaxy Astrophysics, Fermi Gamma-ray Space Telescope
Abstract

The Fermi bubbles are two large structures above and below the Galactic Plane. They are first discovered by Fermi-LAT and thought to be related to the jet or the wind from the Galactic center. The DArk Matter Particle Explorer (DAMPE) is a space-borne high energy particle telescope aiming at measuring cosmic rays and photons in a broad energy range. In this work, we use 4.8 years of DAMPE photon data to search for the emission from the Fermi Bubbles. We calculate the TS values of the lobes and the significance of its curved spectrum. The obtained spectral parameters are then compared with those from the Fermi-LAT. We also search for the emission from the cocoon in the southeast part of lobes. Since the Galactic diffuse emission (GDE) model is a major source of systematic uncertainty, we also switch to the GDE models calculated with Galprop and evaluate the influence.

Published
2021
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6. Measurement of the Boron to Carbon Flux Ratio in Cosmic Rays with the DAMPE Experiment

Author

Jinglai Duan, Peng Yang, Xian Qiang Li, Maria Ionica, Jie Kong, E. Casilli, Wei Liang Li, M. M. Ma, Yan Zhang, Ya Peng Zhang, Y. Z. Gong, Z. X. Dong, Y. M. Hu, Yi Zhang, Chang Qing Feng, Tie Kuang Dong, K. Gong, X. Y. Peng, G. Z. Shang, Shuang Xue Han, Q. An, Hao Ting Dai, Chuan Yue, Shu Xin Wang, P. Azzarello, Qiang Yuan, D. Kyratzis, Y. Y. Huang, Yuan Zhu Wang, S. B. Liu, Xin Wu, Kai Kai Duan, Y. H. Yu, En Heng Xu, D. Mo, Yun Long Zhang, Jing Xing Song, P. Fusco, Yong Jie Zhang, R. Qiao, A. Parenti, R. R. Fan, C. Perrina, Hui Jun Yao, J. N. Rao, Y. F. Wei, M. M. Salinas, Yan Fang Wang, M. N. Mazziotta, H. Su, Zun Lei Xu, J. J. Zang, A. Ruina, Deng Yi Chen, Hao Ran Sun, Zhao Qiang Shen, Xun Feng Zhao, Huaguang Wang, J. J. Wei, L. G. Wang, Dong Ya Guo, I. Di Santo, Zhi Hui Xu, Yi-Zhong Fan, P. Bernardini, Tao Ma, Hao Liu, Jie Liu, Guang Shun Huang, Ying Wang, Zhan-Fang Chen, Sha Sha Wu, Dampe, Zi Zong Xu, Yu Xing Cui, Chuan Ning Luo, Sheng Xia Zhang, Yang Haibo, Giacinto Donvito, Xiao Yuan Huang, Yao Ming Liang, F. Loparco, Li-Bo Wu, J. L. Chen, Da Ming Wei, Qi Ding, Zhan Fang Chen, F. de Palma, L. Silveri, Guan Wen Yuan, Kun Fang, D. Droz, Yang Liu, G. Marsella, Andrii Tykhonov, Jin Zhou Wang, Hai Tao Xu, Xiang Li, Xiao Jun Bi, Min Gao, Jin Chang, F. Gargano, Zhi Yong Zhang, Fang Fang, Peng Xiong Ma, Di Wu, Jian Wu, M. Y. Cui, Ya Qing Yang, Li Bo Wu, Xiao Yang Niu, X. J. Teng, W. H. Shen, Z. T. Shen, Xu Pan, Cong Zhao, Ming-Yang Cui, M. S. Cai, Lei Feng, W. X. Peng, Jian Hua Guo, I. De Mitri, Xiao Yong Ma, Zi Qing Xia, A. De Benedittis, E. Catanzani, Wen Hao Li, F. C. T. Barbato, M. Stolpovskiy, A. Kotenko, Shen Wang, A. Surdo, Hong Yun Zhao, F. Alemanno, C. Liu, Xiao Lian Wang, V. Gallo, W. Zhang, Z. Y. Sun, Chang Yi Zhou, Wei Jiang, D. D'Urso, T. S. Cui, Shi Jun Lei, Zhe Zhang, G. F. Xue, Yong Qiang Zhang, and Meng Su

Subjects
Physics, Nuclear physics, Range (particle radiation), High energy particle, chemistry, Astrophysics::High Energy Astrophysical Phenomena, Dark matter, Detector, chemistry.chemical_element, Particle, Cosmic ray, Boron, Carbon
Abstract

The DArk Matter Particle Explorer (DAMPE), a space-based high energy particle detector, has been operated on-orbit for more than five years. The large geometric factor and good charge resolution enable DAMPE to have very good potential to measure cosmic-rays up to 100 TeV. Knowledge of the boron to carbon (B/C) flux ratio is very important in understanding the prop- agation of cosmic rays, especially in TeV energy range. In this contribution, the latest progress of the B/C flux ratio analysis based on the flight data collected by DAMPE during the 5 years of operation, is presented.

Published
2021
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7. Measurement of the Cosmic Ray Helium Energy Spectrum from 70 GeV to 80 TeV with the DAMPE Space Mission

Author

Fengtao Zhang, Y. F. Wang, Y. Y. Huang, Xiangpeng Guo, Jinfei Wu, D. Droz, J. N. Rao, Jinglai Duan, Yang Haibo, C. Liu, D. M. Wei, Zongye Zhang, X. Y. Ma, P. Azzarello, P. Fusco, Z. Y. Sun, Niu Xiaoyang, I. De Mitri, W. Zhang, Cihang Luo, C. Q. Feng, Yu Xing Cui, X. X. Li, M. S. Cai, Z.-Q. Shen, G. Marsella, X. L. Wang, S. Wang, F. Loparco, Guan Wen Yuan, Y. F. Wei, Jin Chang, Y. J. Zhang, Giacinto Donvito, W. X. Peng, J. L. Chen, Q. An, S. B. Liu, S. C. Wen, F. Gargano, Xiulian Pan, Y. Z. Gong, Cang Zhao, Yuqing Fan, T. S. Cui, H. T. Xu, A. De Benedittis, E. Catanzani, M. M. Salinas, Y. H. Yu, Zhao-Min Wang, Yun Long Zhang, Andrii Tykhonov, Wei Liu, Dingsong Wu, Zhenyu Zhang, Yifan Yang, G. F. Xue, Fang Fang, Pengtao Yang, M. Di Santo, R. Qiao, Yaohui Zhang, Xian Qiang Li, X. J. Bi, Chuan Yue, Min Gao, Z. Q. Xia, Shumei Wu, X. Y. Peng, M. M. Ma, Wenhan Jiang, J. Z. Wang, F. C. T. Barbato, M. Stolpovskiy, Hengchang Liu, F. Alemanno, P. Bernardini, J. J. Wei, Lihui Wu, Yujuan Liu, J. Liu, Yao Ming Liang, Z. Xu, A. Parenti, L. Feng, Yun-Zhi Zhang, A. Ruina, D. Mo, M. Y. Cui, Xin Wu, L. Silveri, Jun-jun Guo, Yu-Sa Wang, Hong Yun Zhao, W. Li, Hu-Rong Yao, Jinyuo Song, Z. Z. Xu, Z. X. Dong, Yan Fang Wang, Kun Fang, Y. Zhang, A. D'Amone, H. Su, Meng Su, A. Kotenko, Maria Ionica, Jie Kong, Shi-Jun Lei, Sheng Xia Zhang, Q. Yuan, Guangshun Huang, R. R. Fan, Peng-Xiong Ma, Xun Feng Zhao, Zhi Hui Xu, S.X. Li, A. Surdo, Yu-Xuan Zhu, X. J. Teng, Tie-Kuang Dong, W. H. Shen, Z. T. Shen, D. D'Urso, Zu-Cheng Chen, L. G. Wang, Dong Ya Guo, Xiaoyuan Huang, Y. M. Hu, F. de Palma, Hao Ting Dai, C. Perrina, Tianxiao Ma, Donghong Chen, Kai-Kai Duan, Maksym Deliyergiyev, D. Kyratzis, K. Gong, Chengrui Zhou, Mn Mazziotta, G. Z. Shang, Shuang Xue Han, J. J. Zang, Huaguang Wang, Alemanno F., An Q., Azzarello P., Barbato F.C.T., Bernardini P., Bi X.J., Cai M.S., Catanzani E., Chang J., Chen D.Y., Chen J.L., Chen Z.F., Cui M.Y., Cui T.S., Cui Y.X., Dai H.T., D'amone A., De Benedittis A., De Mitri I., De Palma F., Deliyergiyev M., Di Santo M., Dong T.K., Dong Z.X., Donvito G., Droz D., Duan J.L., Duan K.K., D'urso D., Fan R.R., Fan Y.Z., Fang K., Fang F., Feng C.Q., Feng L., Fusco P., Gao M., Gargano F., Gong K., Gong Y.Z., Guo D.Y., Guo J.H., Guo X.L., Han S.X., Hu Y.M., Huang G.S., Huang X.Y., Huang Y.Y., Ionica M., Jiang W., Kong J., Kotenko A., Kyratzis D., Lei S.J., Li S., Li W.L., Li X., Li X.Q., Liang Y.M., Liu C.M., Liu H., Liu J., Liu S.B., Liu W.Q., Liu Y., Loparco F., Luo C.N., Ma M., Ma P.X., Ma T., Ma X.Y., Marsella G., Mazziotta M.N., Mo D., Niu X.Y., Pan X., Parenti A., Peng W.X., Peng X.Y., Perrina C., Qiao R., Rao J.N., Ruina A., Salinas M.M., Shang G.Z., Shen W.H., Shen Z.Q., Shen Z.T., Silveri L., Song J.X., Stolpovskiy M., Su H., Su M., Sun Z.Y., Surdo A., Teng X.J., Tykhonov A., Wang H., Wang J.Z., Wang L.G., Wang S., Wang X.L., Wang Y., Wang Y.F., Wang Y.Z., Wang Z.M., Wei D.M., Wei J.J., Wei Y.F., Wen S.C., Wu D., Wu J., Wu L.B., Wu S.S., Wu X., Xia Z.Q., Xu H.T., Xu Z.H., Xu Z.L., Xu Z.Z., Xue G.F., Yang H.B., Yang P., Yang Y.Q., Yao H.J., Yu Y.H., Yuan G.W., Yuan Q., Yue C., Zang J.J., Zhang F., Zhang S.X., Zhang W.Z., Zhang Y., Zhang Y.J., Zhang Y.L., Zhang Y.P., Zhang Y.Q., Zhang Z., Zhang Z.Y., Zhao C., Zhao H.Y., Zhao X.F., Zhou C.Y., Zhu Y., Alemanno, F., An, Q., Azzarello, P., Barbato, F. C. T., Bernardini, P., Bi, X. J., Cai, M. S., Catanzani, E., Chang, J., Chen, D. Y., Chen, J. L., Chen, Z. F., Cui, M. Y., Cui, T. S., Cui, Y. X., Dai, H. T., D’Amone, A., De Benedittis, A., De Mitri, I., de Palma, F., Deliyergiyev, M., Di Santo, M., Dong, T. K., Dong, Z. X., Donvito, G., Droz, D., Duan, J. L., Duan, K. K., D’Urso, D., Fan, R. R., Fan, Y. Z., Fang, K., Fang, F., Feng, C. Q., Feng, L., Fusco, P., Gao, M., Gargano, F., Gong, K., Gong, Y. Z., Guo, D. Y., Guo, J. H., Guo, X. L., Han, S. X., Hu, Y. M., Huang, G. S., Huang, X. Y., Huang, Y. Y., Ionica, M., Jiang, W., Kong, J., Kotenko, A., Kyratzis, D., Lei, S. J., Li, S., Li, W. L., Li, X., Li, X. Q., Liang, Y. M., Liu, C. M., Liu, H., Liu, J., Liu, S. B., Liu, W. Q., Liu, Y., Loparco, F., Luo, C. N., Ma, M., Ma, P. X., Ma, T., Ma, X. Y., Marsella, G., Mazziotta, M. N., Mo, D., Niu, X. Y., Pan, X., Parenti, A., Peng, W. X., Peng, X. Y., Perrina, C., Qiao, R., Rao, J. N., Ruina, A., Salinas, M. M., Shang, G. Z., Shen, W. H., Shen, Z. Q., Shen, Z. T., Silveri, L., Song, J. X., Stolpovskiy, M., Su, H., Su, M., Sun, Z. Y., Surdo, A., Teng, X. J., Tykhonov, A., Wang, H., Wang, J. Z., Wang, L. G., Wang, S., Wang, X. L., Wang, Y., Wang, Y. F., Wang, Y. Z., Wang, Z. M., Wei, D. M., Wei, J. J., Wei, Y. F., Wen, S. C., Wu, D., Wu, J., Wu, L. B., Wu, S. S., Wu, X., Xia, Z. Q., Xu, H. T., Xu, Z. H., Xu, Z. L., Xu, Z. Z., Xue, G. F., Yang, H. B., Yang, P., Yang, Y. Q., Yao, H. J., Yu, Y. H., Yuan, G. W., Yuan, Q., Yue, C., Zang, J. J., Zhang, F., Zhang, S. X., Zhang, W. Z., Zhang, Y., Zhang, Y. J., Zhang, Y. L., Zhang, Y. P., Zhang, Y. Q., Zhang, Z., Zhang, Z. Y., Zhao, C., Zhao, H. Y., Zhao, X. F., Zhou, C. Y., and Zhu, Y.

Subjects
Astrophysics::High Energy Astrophysical Phenomena, Dark matter, General Physics and Astronomy, chemistry.chemical_element, FOS: Physical sciences, Cosmic ray, Space (mathematics), 01 natural sciences, 7. Clean energy, Cosmic ray, helium, High Energy Physics - Experiment, Nuclear physics, High Energy Physics - Experiment (hep-ex), 0103 physical sciences, Energy spectrum, cosmic rays, dark matter, space, crystals, 010306 general physics, Helium, Physics, High Energy Astrophysical Phenomena (astro-ph.HE), COSMIC cancer database, detector, Settore FIS/01 - Fisica Sperimentale, calibration, chemistry, Particle, Astrophysics - High Energy Astrophysical Phenomena, Nucleon, performance
Abstract

The measurement of the energy spectrum of cosmic ray helium nuclei from 70 GeV to 80 TeV using 4.5 years of data recorded by the DArk Matter Particle Explorer (DAMPE) is reported in this work. A hardening of the spectrum is observed at an energy of about 1.3 TeV, similar to previous observations. In addition, a spectral softening at about 34 TeV is revealed for the first time with large statistics and well controlled systematic uncertainties, with an overall significance of $4.3\sigma$. The DAMPE spectral measurements of both cosmic protons and helium nuclei suggest a particle charge dependent softening energy, although with current uncertainties a dependence on the number of nucleons cannot be ruled out., Comment: 11 pages, 13 figures, published in Phys. Rev. Lett. Add one more digit for first three columns in Table S2

Published
2021

8. Abnormal ventral attention network homogeneity in patients with right temporal lobe epilepsy

Author

D-B, Li, R-S, Liu, X, Wang, P-A, Xiong, H-W, Ren, Y-F, Wei, L-M, Zhang, and Y-J, Gao

Subjects
Adult, Male, Epilepsy, Temporal Lobe, Brain, Default Mode Network, Humans, Cognitive Dysfunction, Female
Abstract

The attention network is the structural basis of cognitive function. As one of the two known attention networks, the ventral attention network (VAN) has a significant impact on the cognitive impairment of patients with epilepsy. Nevertheless, changes in network homogeneity (NH) are rarely reported in the VAN of right temporal lobe epilepsy (rTLE) patients. Therefore, we explored the NH of the VAN in rTLE patients in this study.Seventy rTLE patients and 69 healthy controls were recruited. All participants underwent resting-state functional magnetic resonance imaging (fMRI), which was the primary method of evaluation. The executive control reaction time (ECRT) was examined via the attentional network test. The Data Processing Assistant for Resting-State fMRI (DPARSF) was used to analyze NH. The independent component analysis (ICA) and correlation analysis were used in data analysis.Compared to the control group, patients with right temporal lobe epilepsy showed a lower NH in the right superior temporal gyrus, and a longer ECRT. However, abnormal NH values had no significant association with the clinical measurements.Patients with right temporal lobe epilepsy have abnormal NH values in the VAN, and the executive functions in rTLE patients are also altered. The altered NH values in VAN may help provide new insights into the pathophysiology of cognitive impairment in rTLE.

Published
2021

9. Spirometra erinaceieuropaei severely infect frogs and snakes from food markets in Guangdong, China: implications a highly risk for zoonotic sparganosis

Author

F M, Wang, W Y, Li, S P, Gong, Y F, Wei, Y, Ge, G D, Yang, and J J, Xiao

Abstract

Sparganosis is a parasitic disease caused by plerocercoid larvae of the genus Spirometra. In China, the main source of sparganosis is from Guangdong, 16.1% of the country's human sparganosis cases occur in this province. Frequent international trade of amphibians and reptiles in Guangdong may introduce new species of Spirometra into the local market. In this study, a large-scale, high-intensity sampling survey was conducted to find out the causative species and epidemic situation of Sparganosis in Guangdong. The prevalence of sparganum infection in five species of frogs (Boulengerana guentheri, Fejervarya multistriata, Hoplobatrachus chinensis, Pelophylax nigromaculatus and Quasipaa spinosa) and nine species of snakes (Elaphe carinata, Lycodon rufozonatum, Hypsiscopus plumbea, Ptyas dhumnades, P. korros, P. mucosa, Naja atra, Sinonatrix annularis and Xenochrophis piscator) was investigated in Guangdong, Southern China from May 2014 to August 2015. The results showed that 9.8% (50/511) of the frogs and 40.8% (141/ 346) of snakes were found to be infected by plerocercoids (spargana). To identify the species of the collected spargana, a partial sequence of the mitochondrial cytochrome c oxidase subunit1 gene (cox1) was amplified and sequenced. Phylogenetic analysis identified all the spargana specimens as Spirometra erinaceieuropaei. Our study indicated that S. erinaceieuropaei, a highly pathogenic parasite, is the only causative agent of sparganosis in Guangdong, China. This study suggests that the large numbers of frogs and snakes in food markets in Guangdong may impact public health in China by transmitting S. erinaceieuropaei sparganum. Additional steps should be considered by the governments and public health agencies to prevent the risk of food-associated Spirometra infections in humans in China.

Published
2021

10. Effects of APELIN-13 on the expression of IL-6, TNF-α, and IFN-γ in rats with experimental autoimmune neuritis

Author

Y F, Wei, P, Yin, L, Liu, S S, Wu, L, Jia, and S, Sun

Subjects
Interferon-gamma, Interleukin-6, Tumor Necrosis Factor-alpha, Animals, Intercellular Signaling Peptides and Proteins, Neuritis, Autoimmune, Experimental, Rats
Abstract

The objective of this paper was to study the effects of PYR-ARG-PRO-ARG-LEU-SER-HIS-YSGLY-PRO-MET-PRO-PHE-OH (APELIN-13) on the expression of inflammatory factors interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and interferon-γ (IFN-γ) in rats with experimental autoimmune neuritis (EAN). A total of 30 rats were divided into a control group, an EAN group, and an APELIN-13 group. Enzyme-linked immunosorbent assay (ELISA) was used to detect the levels of IL-6, TNF-α, and IFN-γ in rat plasma. Real-time quantitative Polymerase Chain Reaction (PCR) and Western blot were used to detect the protein and mRNA expression of IL-6, TNF-α, and IFN-γ in rat lymph nodes. In the EAN group, the infiltration of various types of inflammatory cells and focal demyelination were observed near the nerve fascicles of sciatic nerves. Compared with the EAN group, the infiltration of inflammatory cells and demyelination in the APELIN-13 group decreased significantly. The levels of plasma IL-6, TNF-α, and IFN-γ in the EAN group were significantly higher than those in the control group (P0.05) but significantly lower than those in the APELIN-13 group (P0.05). Compared with the control group, the mRNA and protein expression of IL-6, TNF-α, and IFN-γ increased significantly (P0.05) in the EAN group but decreased significantly in the APELIN-13 group (P0.05). In conclusion, APELIN-13 exerted a protective effect against EAN in rats.

Published
2019

11. Measurement of the cosmic ray proton spectrum from 40 GeV to 100 TeV with the DAMPE satellite

Author

Chi Wang, Y. Z. Gong, Yujuan Liu, Kai-Kai Duan, Yaohui Zhang, L. G. Wang, Dong Ya Guo, Cihang Luo, X. Y. Peng, Jie Liu, Guangshun Huang, Zhi-Yu Sun, S. Wang, R. R. Fan, Maria Ionica, Jie Kong, Peng-Xiong Ma, Zhi Hui Xu, Xiaoyuan Huang, Yu-Sa Wang, N. H. Liao, L. Feng, Michael Ma, H. Liu, X. Y. Ma, Z. X. Dong, Dingsong Wu, Jun-jun Guo, Niu Xiaoyang, A. D'Amone, K. Gong, S. C. Wen, I. De Mitri, P. Azzarello, Min Gao, Chengrui Zhou, Shengxia Zhang, Shumei Wu, Mn Mazziotta, G. Z. Shang, K. Xi, Xian-Min Jin, F. Loparco, Xin-Fu Zhao, Z. Z. Xu, Y. Y. Huang, Shuang Xue Han, X. L. Wang, Zhongjie Yang, Y. H. Yu, G. Marsella, Zhao-Min Wang, Jinglai Duan, Andrii Tykhonov, S. B. Liu, Y. Zhang, Meng Su, Q. An, Y. F. Dong, C. Q. Feng, Xiulian Pan, Ju-Xian Song, Peidong Yang, W. Li, Y. M. Hu, S.X. Li, S. Y. Ma, H. T. Xu, Jindong Zhang, Z. Q. Xia, Yali Zhou, Jialong Chen, J. Z. Wang, X. X. Li, H. Su, M. S. Cai, Jian Wu, X. J. Bi, Haiqiong Wang, Yifan Yang, Tianxiao Ma, F. J. Gan, Donghong Chen, J. J. Zang, Hao Ting Dai, Huaguang Wang, Zhoubin Zhang, P. Bernardini, Z.-Q. Shen, F. Gargano, H. S. Chen, Manyu Ding, Y. F. Liang, R. Qiao, D. Droz, Chuan Yue, W. X. Peng, Y. F. Wei, Shi-Jun Lei, Q. Yuan, Y. J. Zhang, P. Fusco, Yun-Zhi Zhang, A. Surdo, YM Liang, Jiang Chang, J. J. Wei, Lihui Wu, D. Mo, Y. Li, Giacinto Donvito, A. De Benedittis, Wangli Chen, Yang Haibo, Quan Wang, R. Asfandiyarov, M. Di Santo, J. Y. Zhang, Xi Zhu, J. N. Rao, D. M. Wei, Zongye Zhang, Hong Yun Zhao, Yu-Xuan Zhu, D. D'Urso, Hu-Rong Yao, S. Vitillo, Yen-Po Wang, Yugang Zhang, M. Y. Cui, M. M. Salinas, Fang Fang, Wei Liu, T. S. Cui, Huan Zhao, Z. Xu, X. J. Teng, Tie-Kuang Dong, W. H. Shen, Z. T. Shen, Shanta M. Zimmer, Xian Qiang Li, Xin Wu, C. Liu, Y. F. Wang, V. Gallo, W. Zhang, Wei Jiang, Yuqing Fan, Fengtao Zhang, G. F. Xue, Pengchao Zhang, Xiangpeng Guo, Xixian Wang, An Q., Asfandiyarov R., Azzarello P., Bernardini P., Bi X. J., Cai M. S., Chang J., Chen D. Y., Chen H. F., Chen J. L., Chen W., Cui M. Y., Cui T. S., Dai H. T., D'Amone A., De Benedittis A., De Mitri I., Di Santo M., Ding M., Dong T. K., Dong Y. F., Dong Z. X., Donvito G., Droz D., Duan J. L., Duan K. K., D'Urso D., Fan R. R., Fan Y. Z., Fang F., Feng C. Q., Feng L., Fusco P., Gallo V., Gan F. J., Gao M., Gargano F., Gong K., Gong Y. Z., Guo D. Y., Guo J. H., Guo X. L., Han S. X., Hu Y. M., Huang G. S., Huang X. Y., Huang Y. Y., Ionica M., Jiang W., Jin X., Kong J., Lei S. J., Li S., Li W. L., Li X., Li X. Q., Li Y., Liang Y. F., Liang Y. M., Liao N. H., Liu C. M., Liu H., Liu J., Liu S. B., Liu W. Q., Liu Y., Loparco F., Luo C. N., Ma M., Ma P. X., Ma S. Y., Ma T., Ma X. Y., Marsella G., Mazziotta M. N., Mo D., Niu X. Y., Pan X., Peng W. X., Peng X. Y., Qiao R., Rao J. N., Salinas M. M., Shang G. Z., Shen W. H., Shen Z. Q., Shen Z. T., Song J. X., Su H., Su M., Sun Z. Y., Surdo A., Teng X. J., Tykhonov A., Vitillo S., Wang C., Wang H., Wang H. Y., Wang J. Z., Wang L. G., Wang Q., Wang S., Wang X. H., Wang X. L., Wang Y. F., Wang Y. P., Wang Y. Z., Wang Z. M., Wei D. M., Wei J. J., Wei Y. F., Wen S. C., Wu D., Wu J., Wu L. B., Wu S. S., Wu X., Xi K., Xia Z. Q., Xu H. T., Xu Z. H., Xu Z. L., Xu Z. Z., Xue G. F., Yang H. B., Yang P., Yang Y. Q., Yang Z. L., Yao H. J., Yu Y. H., Yuan Q., Yue C., Zang J. J., Zhang F., Zhang J. Y., Zhang J. Z., Zhang P. F., Zhang S. X., Zhang W. Z., Zhang Y., Zhang Y. J., Zhang Y. L., Zhang Y. P., Zhang Y. Q., Zhang Z., Zhang Z. Y., Zhao H., Zhao H. Y., Zhao X. F., Zhou C. Y., Zhou Y., Zhu X., Zhu Y., Zimmer S., An, Q., Asfandiyarov, R., Azzarello, P., Bernardini, P., Bi, X. J., Cai, M. S., Chang, J., Chen, D. Y., Chen, H. F., Chen, J. L., Chen, W., Cui, M. Y., Cui, T. S., Dai, H. T., D'Amone, A., De Benedittis, A., De Mitri, I., Di Santo, M., Ding, M., Dong, T. K., Dong, Y. F., Dong, Z. X., Donvito, G., Droz, D., Duan, J. L., Duan, K. K., D'Urso, D., Fan, R. R., Fan, Y. Z., Fang, F., Feng, C. Q., Feng, L., Fusco, P., Gallo, V., Gan, F. J., Gao, M., Gargano, F., Gong, K., Gong, Y. Z., Guo, D. Y., Guo, J. H., Guo, X. L., Han, S. X., Hu, Y. M., Huang, G. S., Huang, X. Y., Huang, Y. Y., Ionica, M., Jiang, W., Jin, X., Kong, J., Lei, S. J., Li, S., Li, W. L., Li, X., Li, X. Q., Li, Y., Liang, Y. F., Liang, Y. M., Liao, N. H., Liu, C. M., Liu, H., Liu, J., Liu, S. B., Liu, W. Q., Liu, Y., Loparco, F., Luo, C. N., Ma, M., Ma, P. X., Ma, S. Y., Ma, T., Ma, X. Y., Marsella, G., Mazziotta, M. N., Mo, D., Niu, X. Y., Pan, X., Peng, W. X., Peng, X. Y., Qiao, R., Rao, J. N., Salinas, M. M., Shang, G. Z., Shen, W. H., Shen, Z. Q., Shen, Z. T., Song, J. X., Su, H., Su, M., Sun, Z. Y., Surdo, A., Teng, X. J., Tykhonov, A., Vitillo, S., Wang, C., Wang, H., Wang, H. Y., Wang, J. Z., Wang, L. G., Wang, Q., Wang, S., Wang, X. H., Wang, X. L., Wang, Y. F., Wang, Y. P., Wang, Y. Z., Wang, Z. M., Wei, D. M., Wei, J. J., Wei, Y. F., Wen, S. C., Wu, D., Wu, J., Wu, L. B., Wu, S. S., Wu, X., Xi, K., Xia, Z. Q., Xu, H. T., Xu, Z. H., Xu, Z. L., Xu, Z. Z., Xue, G. F., Yang, H. B., Yang, P., Yang, Y. Q., Yang, Z. L., Yao, H. J., Yu, Y. H., Yuan, Q., Yue, C., Zang, J. J., Zhang, F., Zhang, J. Y., Zhang, J. Z., Zhang, P. F., Zhang, S. X., Zhang, W. Z., Zhang, Y., Zhang, Y. J., Zhang, Y. L., Zhang, Y. P., Zhang, Y. Q., Zhang, Z., Zhang, Z. Y., Zhao, H., Zhao, H. Y., Zhao, X. F., Zhou, C. Y., Zhou, Y., Zhu, X., Zhu, Y., and Zimmer, S.

Subjects
dark matter, cosmic rays, space, Proton, Milky Way, Astrophysics::High Energy Astrophysical Phenomena, Dark matter, FOS: Physical sciences, Cosmic ray, Astrophysics, Astrophysics::Cosmology and Extragalactic Astrophysics, Kinetic energy, 01 natural sciences, 0103 physical sciences, 010306 general physics, Nuclear Experiment, Research Articles, Physics, High Energy Astrophysical Phenomena (astro-ph.HE), Spectral index, Multidisciplinary, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, Settore FIS/01 - Fisica Sperimentale, SciAdv r-articles, Physics::Accelerator Physics, High Energy Physics::Experiment, Astrophysics - High Energy Astrophysical Phenomena, Research Article
Abstract

DAMPE satellite has directly measured the cosmic ray proton spectrum from 40 GeV to 100 TeV and revealed a new feature at about 13.6 TeV., The precise measurement of the spectrum of protons, the most abundant component of the cosmic radiation, is necessary to understand the source and acceleration of cosmic rays in the Milky Way. This work reports the measurement of the cosmic ray proton fluxes with kinetic energies from 40 GeV to 100 TeV, with 2 1/2 years of data recorded by the DArk Matter Particle Explorer (DAMPE). This is the first time that an experiment directly measures the cosmic ray protons up to ~100 TeV with high statistics. The measured spectrum confirms the spectral hardening at ~300 GeV found by previous experiments and reveals a softening at ~13.6 TeV, with the spectral index changing from ~2.60 to ~2.85. Our result suggests the existence of a new spectral feature of cosmic rays at energies lower than the so-called knee and sheds new light on the origin of Galactic cosmic rays.

Published
2019

12. The on-orbit calibration of DArk Matter Particle Explorer

Author

Chang Qing Feng, A. D'Amone, X.Q. Ma, K. Gong, D. Mo, R. Asfandiyarov, G. Ambrosi, Y. M. Hu, Peng-Xiong Ma, Xun Feng Zhao, Zhi Hui Xu, Jinglai Duan, Tianxiao Ma, G. Z. Shang, H. T. Xu, C. Liu, X. Y. Ma, M. Y. Cui, S. C. Wen, Chenchen Wang, J. J. Zang, Deng Yi Chen, Xixian Wang, M. M. Salinas, Niu Xiaoyang, Yaping Wang, Shanta M. Zimmer, J. N. Rao, Haiqiong Wang, Da Ming Wei, Z. Y. Sun, Hao Ting Dai, V. Gallo, Q. An, Peidong Yang, Honglong Wang, D. D’Urso, Yuan Zhu Wang, Xiulian Pan, W. Zhang, I. De Mitri, H. Liu, Yang Haibo, Wei Liang Li, D.L. Zhang, H. S. Chen, Min Gao, Li Bo Wu, A. De Benedittis, Wangli Chen, Xi Zhu, Shuyao Li, X.B. Tian, Paolo Bernardini, J.N. Dong, Sha Wu, Y. Q. Zhang, Hu-Rong Yao, Kai-Kai Duan, Y. F. Wei, Jin Chang, Jiangtao Guo, F. J. Gan, S. Y. Ma, Wei Jiang, Z. Q. Xia, Yifan Yang, L. G. Wang, P. Azzarello, Y. J. Zhang, F. Gargano, Zhenyu Zhang, Maria Ionica, Jie Kong, Y. F. Liang, Yali Zhou, Jing Xing Song, M. Di Santo, Xin Wu, Y. F. Wang, R. R. Fan, R. Qiao, M. Caragiulo, Yuqing Fan, N. H. Liao, Jindan Zhang, Qian Wang, Y.L. Xin, Jie Liu, Zhoubin Zhang, Y. H. Yu, Zhao-Qiang Shen, T. S. Cui, Zhao-Min Wang, Yun Long Zhang, Yao Ming Liang, G. F. Xue, Shengxia Zhang, Zhongjie Yang, J. J. Wei, Z. Xu, Dan Jiang, F. Loparco, Laiyu Zhang, S. Vitillo, X. L. Wang, Wei Liu, Y. Zhang, Yongxiang Liu, J.B. Zhang, J. L. Chen, Qing Yuan, Meng Su, Z.Z. Xu, G. Marsella, Andrii Tykhonov, S. Wang, X. J. Teng, Tie-Kuang Dong, M. M. Ma, Zhang Yalan, Shi-Jun Lei, D. Droz, Fengtao Zhang, Huan Zhao, S. B. Liu, M. N. Mazziotta, H. Su, A. Surdo, Jin Zhou Wang, S. Garrappa, W. H. Shen, Yinlian Zhu, Z. T. Shen, Pengchao Zhang, Guang Shun Huang, Fang Fang, X. X. Li, Hong Yun Zhao, M. S. Cai, W. X. Peng, Y. Li, Y. Z. Gong, Z. X. Dong, Chang Yi Zhou, X. Y. Peng, Lingyan Feng, K. Xi, Jindong Zhang, Di Wu, Jian Wu, Chuan Yue, Y. Y. Huang, P. Fusco, Y. F. Dong, Shan-Shan Gao, Manyu Ding, Xian-Min Jin, Ambrosi, G., An, Q., Asfandiyarov, R., Azzarello, P., Bernardini, P., Cai, M. S., Caragiulo, M., Chang, J., Chen, D. Y., Chen, H. F., Chen, J. L., Chen, W., Cui, M. Y., Cui, T. S., Dai, H. T., D'Amone, A., Benedittis, De, Mitri, De, I., Ding, Di Santo, M., Dong, J. N., Dong, T. K., Dong, Y. F., Dong, Z. X., Droz, D., Duan, K. K., Duan, J. L., D'Urso, D., Fan, R. R., Fan, Y. Z., Iemail, Author, Fang, F., Feng, C. Q., Feng, L., Fusco, P., Gallo, V., Gan, F., Gao, M., Gao, S. S., Gargano, F., Garrappa, S., Gong, K., Gong, Y. Z., Guo, J. H., Email Author, Hu, Y. M., Huang, G. S., Huang, Y. Y., Ionica, M., Jiang, D., Jiang, W., Jin, X., Kong, J., Lei, S. J., Li, S., Li, X., Li, W. L., Li, Y., Liang, Y. F., Liang, Y. M., Liao, N. H., Liu, C. M., Liu, H., Liu, J., Liu, S. B., Liu, W. Q., Liu, Y., Loparco, F., Ma, M., Ma, P. X., Ma, S. Y., Ma, T., Ma, X. Q., Ma, X. Y., Marsella, G., Mazziotta, M. N., Mo, D., Niu, X. Y., Pan, X, Peng, X. Y., Peng, W. X., Qiao, R., Rao, J. N., Salinas, M. M., Shang, G. Z., Shen, W. H., Shen, Z. Q., Shen, Z. T., Song, J. X., Su, H., Su, M., Sun, Z. Y., Surdo, A., Teng, X. J., Tian, X. B., Tykhonov, A., Vitillo, S., Wang, C., Wang, H., Wang, H. Y., Wang, J. Z., Wang, L. G., Wang, Q., Wang, S., Wang, X. H., Wang, X. L., Wang, Y. F., Wang, Y. P., Wang, Y. Z., Wang, Z. M., Wen, S. C., Wei, D. M., Wei J. J., A, Wei Y. F., C, Wu D., J, Wu J., A, H, Wu, L. B., c Wu, S. S., k Wu, X., d Xi, K., j Xia, Z. Q., a h, Xin Y. L., A, Xu H. T., K, Xu Z. H., A, H, Xu, Z. L., a Xu, Z. Z., a Xue, G. F., k Yang, H. B., j Yang, P., j Yang, Y. Q., j Yang, Z. L., j Yao, H. J., j Yu, Y. H., j Yuan, Q., a h, Yue C., A, Zang J. J., A, Zhang D. L., C, Zhang F., M, Zhang J. B., C, Zhang J. Y., M, Zhang J. Z., J, Zhang L., A, I, Zhang, P. F., a Zhang, S. X., j Zhang, W. Z., k Zhang, Y., a i, Zhang Y. J., J, Zhang Y. Q., A, Y. L., c Zhang, Y. P., j Zhang, Z., a Zhang, Z. Y., c Zhao, H., m Zhao, H. Y., j Zhao, X. F., k Zhou, C. Y., k Zhou, Y., j Zhu, X., c Zhu, Y., k Zimmer, Ambrosi G., An Q., Asfandiyarov R., Azzarello P., Bernardini P., Cai M. S., Caragiulo M., Chang J., Chen D. Y., Chen H. F., Chen J. L., Chen W., Cui M. Y., Cui T. S., Dai H. T., D'Amone A., De Beneditti, De Mitri, I. Ding, Dong J. N., Dong T. K., Dong Y. F., Dong Z. X., Droz D., Duan K. K., Duan J. L., D'Urso D., Fan R. R., Fan Y. Z., iEmail Author, Fang F., Feng C. Q., Feng L., Fusco P., Gallo V., Gan F., Gao M., Gao S. S., Gargano F., Garrappa S., Gong K., Gong Y. Z., J. H. Email Author, Hu Y. M., Huang G. S., Huang Y. Y., Ionica M., Jiang D., Jiang W., Jin X., Kong J., Lei S. J., Li S., Li X., Li W. L., Li Y., Liang Y. F., Liang Y. M., Liao N. H., Liu C. M., Liu H., Liu J., Liu S. B., Liu W. Q., Liu Y., Loparco F., Ma M., Ma P. X., Ma S. Y., Ma T., Ma X. Q., Ma X. Y., Marsella G., Mazziotta M. N., Mo D., Niu X. Y., Pan X, Peng X. Y., Peng W. X., Qiao R., Rao J. N., Salinas M. M., Shang G. Z., Shen W. H., Shen Z. Q., Shen Z. T., Song J. X., Su H., Su M., Sun Z. Y., Surdo A., Teng X. J., Tian X. B., Tykhonov A., Vitillo S., Wang C., Wang H., Wang H. Y., Wang J. Z., Wang L. G., Wang Q., Wang S., Wang X. H., Wang X. L., Wang Y. F., Wang Y. P., Wang Y. Z., Wang Z. M., Wen S. C., Wei D. M., Wei J. J. a, Wei Y. F. c, Wu D. j, Wu J. a, h Wu, L. B. c Wu, S. S. k Wu, X. d Xi, K. j Xia, Z. Q. a h, Xin Y. L. a, Xu H. T. k, Xu Z. H. a, h Xu, Z. L. a Xu, Z. Z. a Xue, G. F. k Yang, H. B. j Yang, P. j Yang, Y. Q. j Yang, Z. L. j Yao, H. J. j Yu, Y. H. j Yuan, Q. a h, Yue C. a, Zang J. J. a, Zhang D. L. c, Zhang F. m, Zhang J. B. c, Zhang J. Y. m, Zhang J. Z. j, Zhang L. a, i Zhang, P. F. a Zhang, S. X. j Zhang, W. Z. k Zhang, Y. a i, Zhang Y. J. j, Zhang Y. Q. a, Y. L. c Zhang, Y. P. j Zhang, Z. a Zhang, Z. Y. c Zhao, H. m Zhao, H. Y. j Zhao, X. F. k Zhou, C. Y. k Zhou, Y. j Zhu, X. c Zhu, and Y. k Zimmer

Subjects
Physics::Instrumentation and Detectors, Astrophysics::High Energy Astrophysical Phenomena, Dark matter, FOS: Physical sciences, Cosmic ray, Scintillator, 01 natural sciences, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), 0103 physical sciences, Neutron detection, Dark Matter, Instrumentation and Methods for Astrophysics (astro-ph.IM), 010303 astronomy & astrophysics, High Energy Astrophysical Phenomena (astro-ph.HE), Physics, Calorimeter (particle physics), 010308 nuclear & particles physics, Detector, Settore FIS/01 - Fisica Sperimentale, Gamma ray, Astronomy, Astronomy and Astrophysics, Cosmic Rays, South Atlantic Anomaly, High Energy Physics::Experiment, Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - High Energy Astrophysical Phenomena
Abstract

The DArk Matter Particle Explorer (DAMPE), a satellite-based cosmic ray and gamma-ray detector, was launched on December 17, 2015, and began its on-orbit operation on December 24, 2015. In this work we document the on-orbit calibration procedures used by DAMPE and report the calibration results of the Plastic Scintillator strip Detector (PSD), the Silicon-Tungsten tracKer-converter (STK), the BGO imaging calorimeter (BGO), and the Neutron Detector (NUD). The results are obtained using Galactic cosmic rays, bright known GeV gamma-ray sources, and charge injection into the front-end electronics of each sub-detector. The determination of the boundary of the South Atlantic Anomaly (SAA), the measurement of the live time, and the alignments of the detectors are also introduced. The calibration results demonstrate the stability of the detectors in almost two years of the on-orbit operation.

Published
2019

13. The DArk Matter Particle Explorer mission

Author

M. M. Ma, Y.L. Xin, Shengxia Zhang, Y. Y. Huang, Y. Z. Gong, H.Y. Zhao, P. Fusco, Zhao-Qiang Shen, Peidong Yang, Zhao-Min Wang, Yuan Zhu Wang, Maria Ionica, Jie Kong, Yun Long Zhang, F. Loparco, Dan Jiang, J.N. Dong, Y. L. Li, X. Y. Peng, J. L. Chen, H. S. Chen, S. C. Wen, Y. F. Dong, Jinglai Duan, P. Azzarello, N. H. Liao, X. L. Wang, M. M. Salinas, M. Caragiulo, Ya Peng Zhang, M. Pohl, V. Gallo, W. Zhang, Andrii Tykhonov, Niu Xiaoyang, Hai Tao Xu, X. X. Li, Shi-Jun Lei, G. Marsella, Wei Jiang, Min Gao, M. S. Cai, X. Zhu, Z. X. Dong, Yong Zhou, S. Y. Ma, Wei Liang Li, A. De Benedittis, Q. An, Sha Wu, Deng Yi Chen, Y. F. Wei, J.B. Zhang, T.T. Miao, G. F. Xue, Chuan Yue, Z.L. Yang, Y.F. Liang, P. Bernardini, Yifan Yang, Laiyu Zhang, Jianyi Yang, W. X. Peng, Z. M. Zhang, Giacinto Donvito, L. G. Wang, J. G. Lu, Y. J. Zhang, R. Qiao, Shan-Shan Gao, Zi-Qing Xia, Hui Jun Yao, Zhi-Yu Sun, Fang Fang, Yi-Zhong Fan, S. Vitillo, Jie Liu, S. Li, J. J. Wei, R. R. Fan, Lei Feng, Y. Zhu, K. Xi, A. D'Amone, Peng-Xiong Ma, Ping Zhang, Xun Feng Zhao, Jianli Zhang, M. N. Mazziotta, H. Su, Di Wu, Y. M. Hu, Da Ming Wei, Chang Yi Zhou, A. Surdo, Yang Liu, Yen-Po Wang, D. Droz, D. D'Urso, W. Chen, Jian Wu, Jin Zhou Wang, F. Zhang, Q. Wang, Jian Hua Guo, M. Duranti, X. J. Teng, Tie-Kuang Dong, I. De Mitri, Xiao Yong Ma, W. H. Shen, X.B. Tian, Chao Zhang, Z. T. Shen, Hong Yun Zhao, Z. Xu, Chang Qing Feng, T. S. Cui, Chunjie Wang, Ju-Xian Song, G. Ambrosi, Q.Z. Liu, Xiaohui Wang, Haiyan Wang, Y. Zhang, X.Q. Ma, Meng Su, D. Mo, Yan Fang Wang, R. Asfandiyarov, Yao Ming Liang, B. Bertucci, Stephan Zimmer, Guang Shun Huang, Yang Haibo, X. Jin, Zhenyu Zhang, M. Di Santo, Tao Ma, Xin Wu, M. Y. Cui, Yongjie Zhang, Yu-Hong Yu, H. Liu, J. N. Rao, Qiang Yuan, S. B. Liu, Jilong Zhang, Chi Wang, W.Q. Gan, Wenqiang Liu, V. Vagelli, Zi Zong Xu, Jin Chang, F. J. Gan, F. Gargano, D.L. Zhang, H. W. Wang, Kai-Kai Duan, K. Gong, G. Z. Shang, Shu Xin Wang, J. J. Zang, Chang, J., Ambrosi, G., An, Q., Asfandiyarov, R., Azzarello, P., Bernardini, P., Bertucci, B., Cai, M. S., Caragiulo, M., Chen, D. Y., Chen, H. F., Chen, J. L., Chen, W., Cui, M. Y., Cui, T. S., D'Amone, A., DE BENEDITTIS, Antonio, De Mitri, I., DI SANTO, Margherita, Dong, J. N., Dong, T. K., Dong, Y. F., Dong, Z. X., Donvito, G., Droz, D., Duan, K. K., Duan, J. L., Duranti, M., D'Urso, D., Fan, R. R., Fan, Y. Z., Fang, F., Feng, C. Q., Feng, L., Fusco, P., Gallo, V., Gan, F. J., Gan, W. Q., Gao, M., Gao, S. S., Gargano, F., Gong, K., Gong, Y. Z., Guo, J. H., Hu, Y. M., Huang, G. S., Huang, Y. Y., Ionica, M., Jiang, D., Jiang, W., Jin, X., Kong, J., Lei, S. J., Li, S., Li, X., Li, W. L., Li, Y., Liang, Y. F., Liang, Y. M., Liao, N. H., Liu, Q. Z., Liu, H., Liu, J., Liu, S. B., Liu, W. Q., Liu, Y., Loparco, F., Lã¼, J., Ma, M., Ma, P. X., Ma, S. Y., Ma, T., Ma, X. Q., Ma, X. Y., Marsella, G., Mazziotta, M. N., Mo, D., Miao, T. T., Niu, X. Y., Pohl, M., Peng, X. Y., Peng, W. X., Qiao, R., Rao, J. N., Salinas, M. M., Shang, G. Z., Shen, W. H., Shen, Z. Q., Shen, Z. T., Song, J. X., Su, H., Su, M., Sun, Z. Y., Surdo, A., Teng, X. J., Tian, X. B., Tykhonov, A., Vagelli, V., Vitillo, S., Wang, C., Wang, Chi, Wang, H., Wang, H. Y., Wang, J. Z., Wang, L. G., Wang, Q., Wang, S., Wang, X. H., Wang, X. L., Wang, Y. F., Wang, Y. P., Wang, Y. Z., Wen, S. C., Wang, Z. M., Wei, D. M., Wei, J. J., Wei, Y. F., Wu, D., Wu, J., Wu, S. S., Wu, X., Xi, K., Xia, Z. Q., Xin, Y. L., Xu, H. T., Xu, Z. L., Xu, Z. Z., Xue, G. F., Yang, H. B., Yang, J., Yang, P., Yang, Y. Q., Yang, Z. L., Yao, H. J., Yu, Y. H., Yuan, Q., Yue, C., Zang, J. J., Zhang, C., Zhang, D. L., Zhang, F., Zhang, J. B., Zhang, J. Y., Zhang, J. Z., Zhang, L., Zhang, P. F., Zhang, S. X., Zhang, W. Z., Zhang, Y., Zhang, Y. J., Zhang, Y. Q., Zhang, Y. L., Zhang, Y. P., Zhang, Z., Zhang, Z. Y., Zhao, H., Zhao, H. Y., Zhao, X. F., Zhou, C. Y., Zhou, Y., Zhu, X., Zhu, Y., Zimmer, S., DE BENEDITTIS, ANTONIO, DI SANTO, MARGHERITA, and Lü, J.

Subjects
Physics - Instrumentation and Detectors, Satellite launches, Gamma ray observatories, Astrophysics, Galactic cosmic rays, 01 natural sciences, Cosmology, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), Observatory, Detectors and Experimental Techniques, Cosmic rays , dark matter , space experiments, 010303 astronomy & astrophysics, physics.ins-det, Space science missions, Physics, High Energy Astrophysical Phenomena (astro-ph.HE), astro-ph.HE, Astrophysics::Instrumentation and Methods for Astrophysics, Instrumentation and Detectors (physics.ins-det), Cosmology, Galaxies, Gamma rays, Tellurium compounds, Chinese Academy of Sciences, Dark matter particles, Explorer missions, Galactic cosmic rays, Gamma ray observatories, Satellite launches, Scientific objectives, Space science missions, Cosmic rays, Space Science, Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - High Energy Astrophysical Phenomena, Particle Physics - Experiment, Astrophysics and Astronomy, Astrophysics::High Energy Astrophysical Phenomena, Dark matter, FOS: Physical sciences, Cosmic ray, dark matter, Tellurium compounds, 0103 physical sciences, Cosmic rays, Instrumentation and Methods for Astrophysics (astro-ph.IM), 010308 nuclear & particles physics, hep-ex, Gamma rays, Astronomy, Astronomy and Astrophysics, Galaxies, Chinese academy of sciences, Galaxy, Scientific objectives, Dark matter particles, Chinese Academy of Sciences, Satellite, space experiments, Explorer missions, astro-ph.IM
Abstract

The DArk Matter Particle Explorer (DAMPE), one of the four scientific space science missions within the framework of the Strategic Pioneer Program on Space Science of the Chinese Academy of Sciences, is a general purpose high energy cosmic-ray and gamma-ray observatory, which was successfully launched on December 17th, 2015 from the Jiuquan Satellite Launch Center. The DAMPE scientific objectives include the study of galactic cosmic rays up to $\sim 10$ TeV and hundreds of TeV for electrons/gammas and nuclei respectively, and the search for dark matter signatures in their spectra. In this paper we illustrate the layout of the DAMPE instrument, and discuss the results of beam tests and calibrations performed on ground. Finally we present the expected performance in space and give an overview of the mission key scientific goals., 45 pages, including 29 figures and 6 tables. Published in Astropart. Phys

Published
2017

14. Direct detection of a break in the teraelectronvolt cosmic-ray spectrum of electrons and positrons

Author

J. N. Rao, D. M. Wei, P. Azzarello, Peng-Xiong Ma, Y. H. Yu, Shan-Shan Gao, Chi Wang, Q. An, L. G. Wang, YM Liang, Dong Ya Guo, Min Gao, Z. X. Dong, Jie Liu, Tianxiao Ma, Donghong Chen, Wei Liu, Yifan Yang, Zhihua Zhang, Jun-jun Guo, Y. F. Liang, S. Wang, Huan Zhao, D.L. Zhang, X.Q. Ma, Maria Ionica, Jie Kong, G. Ambrosi, Luzhao Feng, Yu-Sa Wang, Fang Fang, N. H. Liao, D. Mo, Niu Xiaoyang, Yaping Wang, R. Qiao, Qiuju Yuan, I. De Mitri, X.B. Tian, Z. Z. Xu, Zheng Wang, Michael Ma, R. Asfandiyarov, X. X. Li, Y. M. Hu, M. S. Cai, Guangshun Huang, M. Di Santo, H. Liu, J.N. Dong, Z.-Q. Shen, Zhongjie Yang, W. X. Peng, Peidong Yang, Jialong Chen, Stephan Zimmer, Y. F. Wei, K. Xi, Laiyu Zhang, Zhi-Yu Sun, W. Li, F. Loparco, X. L. Wang, Chao Zhang, Y. J. Zhang, Y. Z. Gong, Jindong Zhang, X. Y. Ma, M. Duranti, Kai-Kai Duan, Y. Zhang, Yun-Zhi Zhang, R. R. Fan, Valerio Vagelli, Xixian Wang, Ju-Xian Song, G. Marsella, Meng Su, Yaohui Zhang, Xian-Min Jin, S.X. Li, S. B. Liu, Huijun Yao, Andrii Tykhonov, J. J. Wei, Lihui Wu, X. Y. Peng, H. T. Xu, Yujuan Liu, Hong Yun Zhao, Jie Zhang, S. Y. Ma, Z. Q. Xia, Dan Jiang, Yali Zhou, X. J. Teng, Tie-Kuang Dong, S. C. Wen, Y. Li, A. D'Amone, Yi-Zhong Fan, K. Gong, J. Z. Wang, Yugang Zhang, H. S. Chen, Chengrui Zhou, Giacinto Donvito, Yang Haibo, Zhoubin Zhang, P. Bernardini, W. H. Shen, M. Y. Cui, G. Z. Shang, Chuan Yue, Jindan Zhang, Di Wu, Xin-Fu Zhao, Y. Y. Huang, Z. T. Shen, Qian Wang, P. Fusco, Shumei Wu, J. J. Zang, Y. F. Dong, Jinfei Wu, C. Q. Feng, Jinglai Duan, Huaguang Wang, B. Bertucci, Jin Chang, F. J. Gan, F. Gargano, M. N. Mazziotta, H. Su, Haiqiong Wang, Fengtao Zhang, Z. Xu, Pengchao Zhang, Xin Wu, Y. F. Wang, S. Vitillo, D. Droz, T. S. Cui, V. Gallo, W. Zhang, Wei Jiang, G. F. Xue, S. Garrappa, Yu-Xuan Zhu, D. D'Urso, Shi-Jun Lei, M. M. Salinas, Y.L. Xin, Xi Zhu, Shengxia Zhang, A. Surdo, A. De Benedittis, Wangli Chen, Ambrosi, G., An, Q., Asfandiyarov, R., Azzarello, P., Bernardini, P., Bertucci, B., Cai, M. S., Chang, J., Chen, D. Y., Chen, H. F., Chen, J. L., Chen, W., Cui, M. Y., Cui, T. S., D’Amone, A., De Benedittis, A., De Mitri, I., Di Santo, M., Dong, J. N., Dong, T. K., Dong, Y. F., Dong, Z. X., Donvito, G., Droz, D., Duan, K. K., Duan, J. L., Duranti, M., D’Urso, D., Fan, R. R., Fan, Y. Z., Fang, F., Feng, C. Q., Feng, L., Fusco, P., Gallo, V., Gan, F. J., Gao, M., Gao, S. S., Gargano, F., Garrappa, S., Gong, K., Gong, Y. Z., Guo, D. Y., Guo, J. H., Hu, Y. M., Huang, G. S., Huang, Y. Y., Ionica, M., Jiang, D., Jiang, W., Jin, X., Kong, J., Lei, S. J., Li, S., Li, X., Li, W. L., Li, Y., Liang, Y. F., Liang, Y. M., Liao, N. H., Liu, H., Liu, J., Liu, S. B., Liu, W. Q., Liu, Y., Loparco, F., Ma, M., Ma, P. X., Ma, S. Y., Ma, T., Ma, X. Q., Ma, X. Y., Marsella, G., Mazziotta, M. N., Mo, D., Niu, X. Y., Peng, X. Y., Peng, W. X., Qiao, R., Rao, J. N., Salinas, M. M., Shang, G. Z., H. Shen, W., Shen, Z. Q., Shen, Z. T., Song, J. X., Su, H., Su, M., Sun, Z. Y., Surdo, A., Teng, X. J., Tian, X. B., Tykhonov, A., Vagelli, V., Vitillo, S., Wang, C., Wang, H., Wang, H. Y., Wang, J. Z., Wang, L. G., Wang, Q., Wang, S., Wang, X. H., Wang, X. L., Wang, Y. F., Wang, Y. P., Wang, Y. Z., Wen, S. C., Wang, Z. M., Wei, D. M., Wei, J. J., Wei, Y. F., Wu, D., Wu, J., Wu, L. B., Wu, S. S., Wu, X., Xi, K., Xia, Z. Q., Xin, Y. L., Xu, H. T., Xu, Z. L., Xu, Z. Z., Xue, G. F., Yang, H. B., Yang, P., Yang, Y. Q., Yang, Z. L., Yao, H. J., Yu, Y. H., Yuan, Q., Yue, C., Zang, J. J., Zhang, C., Zhang, D. L., Zhang, F., Zhang, J. B., Zhang, J. Y., Zhang, J. Z., Zhang, L., Zhang, P. F., Zhang, S. X., Zhang, W. Z., Zhang, Y., Zhang, Y. J., Zhang, Y. Q., Zhang, Y. L., Zhang, Y. P., Zhang, Z., Zhang, Z. Y., Zhao, H., Zhao, H. Y., Zhao, X. F., Zhou, C. Y., Zhou, Y., Zhu, X., Zhu, Y., and Zimmer, S.

Subjects
Astrophysics::High Energy Astrophysical Phenomena, Dark matter, FOS: Physical sciences, Cosmic ray, Electron, 01 natural sciences, dark matter, High Energy Physics - Experiment, Nuclear physics, High Energy Physics - Experiment (hep-ex), High Energy Physics - Phenomenology (hep-ph), Positron, cosmic rays, 0103 physical sciences, 010303 astronomy & astrophysics, Cherenkov radiation, High Energy Astrophysical Phenomena (astro-ph.HE), Physics, cosmic rays , dark matter , electrons , space experiments, Multidisciplinary, Annihilation, 010308 nuclear & particles physics, Settore FIS/01 - Fisica Sperimentale, Spectrum (functional analysis), electrons, Galaxy, High Energy Physics - Phenomenology, High Energy Physics::Experiment, space experiments, Astrophysics - High Energy Astrophysical Phenomena
Abstract

High energy cosmic ray electrons plus positrons (CREs), which lose energy quickly during their propagation, provide an ideal probe of Galactic high-energy processes and may enable the observation of phenomena such as dark-matter particle annihilation or decay. The CRE spectrum has been directly measured up to $\sim 2$ TeV in previous balloon- or space-borne experiments, and indirectly up to $\sim 5$ TeV by ground-based Cherenkov $\gamma$-ray telescope arrays. Evidence for a spectral break in the TeV energy range has been provided by indirect measurements of H.E.S.S., although the results were qualified by sizeable systematic uncertainties. Here we report a direct measurement of CREs in the energy range $25~{\rm GeV}-4.6~{\rm TeV}$ by the DArk Matter Particle Explorer (DAMPE) with unprecedentedly high energy resolution and low background. The majority of the spectrum can be properly fitted by a smoothly broken power-law model rather than a single power-law model. The direct detection of a spectral break at $E \sim0.9$ TeV confirms the evidence found by H.E.S.S., clarifies the behavior of the CRE spectrum at energies above 1 TeV and sheds light on the physical origin of the sub-TeV CREs., Comment: 18 pages, 6 figures, Nature in press, doi:10.1038/nature24475

Published
2017

15. Problems with and a system to eliminate single-primer PCR product contamination in simple sequence repeat molecular marker-assisted selection in soybean

Author

S C Guan, Jideng Ma, Yao Dan, Y F Wei, and P W Wang

Subjects
Genetic Markers, Base Sequence, fungi, food and beverages, General Medicine, DNA Contamination, Biology, Polymerase Chain Reaction, Molecular biology, law.invention, chemistry.chemical_compound, chemistry, Genetic marker, law, Molecular marker, Primer dimer, Genetics, Soybeans, Primer (molecular biology), Molecular Biology, Applications of PCR, Polymerase chain reaction, DNA Primers, In silico PCR
Abstract

Polymerase chain reaction (PCR) provides a foundation for simple sequence repeat molecular marker-assisted selection (SSR MAS) in soybean. This PCR system and its various conditions have been optimized by many researchers. However, current research on the optimization of the PCR system focuses on double-primer PCR products. We compared single- and double-SSR primer PCR products from 50 soybean samples and found that the use of single-PCR primers in the reaction system can lead to amplified fragments of portions of the SSR primers in the PCR process, resulting in both false-positives and fragment impurity of double-primer PCR amplification, inconvenient for subsequent analysis. We used "single-primer PCR correction" to eliminate interference caused by single-primer nonspecific PCR amplification and improve PCR quality. Using this method, the precision and success rates of SSR MAS in soybean can be increased.

Published
2011
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17. Identification, chromosomal mapping and tissue-specific expression of hREV3 encoding a putative human DNA polymerase zeta

Author

K. C. Carter, B. L. Chow, M. Agustus, Wei Xiao, Y.-F. Wei, Terry Lechler, and T. Fontanie

Subjects
Cancer Research, DNA, Complementary, Saccharomyces cerevisiae Proteins, Molecular Sequence Data, Mutant, DNA-Directed DNA Polymerase, Saccharomyces cerevisiae, Biology, Fungal Proteins, chemistry.chemical_compound, Gene mapping, Complementary DNA, medicine, Animals, Humans, Amino Acid Sequence, Gene, In Situ Hybridization, Fluorescence, Polymerase, Base Sequence, Sequence Homology, Amino Acid, medicine.diagnostic_test, Nucleic acid sequence, Chromosome Mapping, General Medicine, Molecular biology, chemistry, Chromosomes, Human, Pair 1, biology.protein, DNA, Fluorescence in situ hybridization
Abstract

The Saccharomyces cerevisiae REV3 gene encodes the catalytic subunit of a non-essential DNA polymerase zeta, which is required for mutagenesis. The rev3 mutants significantly reduce both spontaneous and DNA damage-induced mutation rates. We have identified human cDNA clones from two different libraries whose deduced amino acid sequences bear remarkable homology to the yeast Rev3, and named this gene hREV3. The hREV3 gene was mapped to chromosome 1p32-33 by fluorescence in situ hybridization. The hREV3 encodes an mRNA of >10 kb, and its expression varies in different tissues and appears to be elevated in some but not all of the tumor cell lines we have examined. In light of recent reports of a putative mouse REV3, these results indicate that mammalian cells may also contain a mutagenic pathway which aids in cell survival at the cost of increased mutation.

Published
1998
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18. Symmetrical peripheral gangrene, an uncommon complication of tuberculosis

Author

C. F. Chen, Y. F. Wei, and Jiun-Ling Wang

Subjects
Male, medicine.medical_specialty, Tuberculosis, Physical examination, Palpation, Fingers, Gangrene, Rare Diseases, medicine, Humans, Laparoscopy, Aged, medicine.diagnostic_test, business.industry, PERIPHERAL GANGRENE, General Medicine, Toes, medicine.disease, Surgery, Abdominal ultrasonography, Chills, Radiology, medicine.symptom, business, Complication
Abstract

A 74-year-old man was admitted with abdominal discomfort, fever and chills in the previous 2 weeks. Physical examination revealed a vague Murphys’ sign on abdominal palpation. Abdominal ultrasonography demonstrated a distended gallbladder and acute cholecystitis was initially diagnosed. He underwent a laparoscopy and multiple caseous nodules …

Published
2011

19. Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage

Author

Jeffrey H Miller, Wendy M. Luther, Claudia Baikalov, Ju-Huei Chiang, Malgorzata M. Slupska, and Y F Wei

Subjects
DNA Repair, DNA repair, Molecular Sequence Data, Biology, Microbiology, DNA Glycosylases, chemistry.chemical_compound, Exon, MUTYH, Escherichia coli, Humans, Amino Acid Sequence, Cloning, Molecular, Molecular Biology, Gene, N-Glycosyl Hydrolases, In Situ Hybridization, Fluorescence, Genetics, Gene map, Base Sequence, Sequence Homology, Amino Acid, cDNA library, Chromosome Mapping, DNA, Molecular biology, chemistry, DNA glycosylase, Chromosomes, Human, Pair 1, Oxidation-Reduction, HeLa Cells, Research Article
Abstract

We have cloned the human mutY gene (hMYH) from both genomic and cDNA libraries. The human gene contains 15 introns and is 7.1 kb long. The 16 exons encode a protein of 535 amino acids that displays 41% identity to the Escherichia coli protein, which provides an important function in the repair of oxidative damage to DNA and helps to prevent mutations from oxidative lesions. The human mutY gene maps on the short arm of chromosome 1, between p32.1 and p34.3.

Published
1996

20. Pulmonary infarction from central venous air embolism mimicking round pneumonia

Author

Y-F Wei, S-C Ku, and L-C Lin

Subjects
medicine.medical_specialty, medicine.diagnostic_test, Pulmonary Infarction, business.industry, medicine.medical_treatment, General Medicine, medicine.disease, Article, Surgery, Pneumonia, Embolism, Superior vena cava, Heart failure, Intravascular volume status, medicine, Radiology, business, Chest radiograph, Central venous catheter
Abstract

A 49-year-old man was diagnosed with dilated cardiomyopathy after presenting with congestive heart failure since 1995. He experienced a flare-up of symptoms after an upper respiratory tract infection 1 week before admission to the coronary care unit (CCU). His dyspnoea improved after treatment with diuretics and inotropes. On day 4 in the CCU he developed a urinary tract infection complicated by septic shock. A central venous catheter (CVC) was inserted over the right internal jugular vein. There was difficulty in performing the catheterisation, and the procedure was prolonged due to an extremely low intravascular volume. Soon after the procedure a round opacity was noted on the chest radiograph (fig 1). At that time there was no purulent sputum, airway symptoms or physical examination compatible with pneumonia. A chest CT scan revealed air emboli in the superior vena cava (arrow, fig 2A) and wedge-shaped pulmonary infarcts with central necrosis at the bilateral lower lobes (fig 2B). Owing to lack of evidence for pulmonary infection, the necrosis was believed to be sterile. The patient died 1 week later from cardiogenic shock with multi-organ failure. Figure 1 Chest radiograph after central venous cannulation showing a round opacity of homogenous density but without airbronchogram in the right lower lung field. Figure 2 (A) Contrast-enhanced chest CT scan showing air bubble trapped around the central venous catheter in the superior vena cava (arrow). (B) Bilateral pleural-based, wedge-shaped, mass-like consolidations with central necrosis in both lower lobes. Venous air embolism can be observed during CVC insertion, after CVC removal, and during other medical procedures or interventions.1–3 In acute care settings, patients with hypovolaemia are at a higher risk of gas embolism during central venous cannulation because of the subatmospheric pressure in these vessels.1 To our knowledge, there has been no previous report of venous air pulmonary infarction mimicking round pneumonia in the English literature. Learning points Patients with a low intravascular volume are at a higher risk of developing venous gas embolism during CVC insertion. Pulmonary infarction from gas embolism can mimic round pneumonia on the chest radiograph.

Published
2009
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21. Purification of a protein histidine kinase from the yeast Saccharomyces cerevisiae. The first member of this class of protein kinases

Author

J M, Huang, Y F, Wei, Y H, Kim, L, Osterberg, and H R, Matthews

Subjects
Fungal Proteins, Molecular Weight, Kinetics, Adenosine Triphosphate, Histidine Kinase, Guanosine Triphosphate, Saccharomyces cerevisiae, Amino Acids, Phosphorylation, Protein Kinases, Substrate Specificity
Abstract

An enzyme of molecular weight 32,000 comprising a single subunit has been isolated from whole cell extracts of the yeast Saccharomyces cerevisiae. In vitro, the enzyme transfers the gamma phosphate of ATP to a protein substrate, histone H4, to produce an alkali-stable phosphorylation. Modification of the substrate histidine with diethylpyrocarbonate prevented phosphorylation. Phosphoamino acid analysis of the phosphorylated substrate showed the presence of 1-phosphohistidine. Hence, the isolated enzyme is a protein histidine kinase. A novel assay for acid-labile alkali-stable protein phosphorylation was used in the purification of the kinase activity to a final specific activity of 2,700 nmol/15 min/mg. The purified enzyme phosphorylates specifically histidine 75 in histone H4 and does not phosphorylate histidine 18 nor histidine residues in any other core histone. Steady state kinetic data are consistent with an ordered sequential reaction with Km values for Mg-ATP and histone H4 of 60 and 17 microM, respectively. The protein histidine kinase requires a divalent cation such as Mg2+, Co2+, or Mn2+ but will not use Ca2+, Zn2+, Cu2+, Fe2+, spermine, or spermidine. This is the first purification of an enzyme that catalyzes N-linked phosphorylation in proteins.

Published
1991

22. Heparin interferes with the biological effectiveness of atriopeptin

Author

S W Holmberg, C S Devine, Y F Wei, Philip Needleman, K M Leahy, and P O Olins

Subjects
medicine.medical_specialty, Arginine, medicine.drug_class, Prohormone, Diuresis, Blood Pressure, Furosemide, Internal medicine, Internal Medicine, medicine, Animals, Protamines, Chromatography, High Pressure Liquid, Dose-Response Relationship, Drug, biology, Heparin, Chemistry, Anticoagulant, Rats, Inbred Strains, Biological activity, Protamine, Rats, Endocrinology, biology.protein, Female, Atrial Natriuretic Factor, medicine.drug
Abstract

The chromatographic mobility of atriopeptin-28 or of the prohormone is markedly altered by preincubation of the peptides with heparin before separation on reverse-phase high performance liquid chromatography. Protamine prevented the heparin effect and reestablished the original migration pattern of the atrial peptides. The addition of heparin to either rat or human plasma samples did not interfere with the atriopeptin immunoreactivity. The influence of heparin on the biological activity of the atriopeptin-28 in anesthetized rats was also investigated. Infusion of heparin (30 U/min) significantly reduced the dose-dependent fall of blood pressure produced by atriopeptin-28, but did not interfere with the hypotensive effect of nitroglycerin. Similarly, infusion of heparin in volume-expanded rats markedly decreased the diuresis produced by atriopeptin-28 without altering the urine volume excreted in response to furosemide. These data suggest that the highly charged molecule heparin can modify the physical and biological properties of atriopeptins, perhaps by binding to the numerous arginine residues (i.e., 5 arginine residues in atriopeptin-28) in the atriopeptin molecules.

Published
1987
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23. Developmental changes in the rat atriopeptin hormonal system

Author

B R Cole, C P Rodi, Y F Wei, Philip Needleman, L D Needleman, Mark L. Day, and Roger C. Wiegand

Subjects
Vasopressin, medicine.medical_specialty, Prohormone, Blood volume, Intracardiac pressure, Biology, Embryonic and Fetal Development, Pregnancy, Internal medicine, medicine, Animals, Fetus, Blood Volume, Heart, Rats, Inbred Strains, General Medicine, medicine.disease, Rats, Endocrinology, Fetal circulation, Animals, Newborn, Regional Blood Flow, Female, Atrial Natriuretic Factor, Hormone, medicine.drug, Research Article
Abstract

We undertook a study of fetal synthesis, storage, and release of atriopeptin (AP). Plasma levels of both atriopeptin immunoreactivity (APir) and the NH2-terminal fragment of the prohormone immunoreactivity (NTFir) were very high in the fetus (4 and 20 times the maternal plasma, respectively). However, the atrial content of the AP was low, but surprisingly, ventricular content of AP was quite high (relative to the adult) in the fetus and fell postnatally. Atrial AP messenger RNA (mRNA) increased with postnatal age, whereas ventricular mRNA was extremely high in the fetus and fell rapidly after birth. High fetal plasma peptide levels may derive from the mother since infusion of exogenous atriopeptin 24 into the mother resulted in parallel increases in fetal and maternal peptide levels. Fetal plasma APir and NTFir levels partially reflect the markedly reduced total renal metabolic capacity compared with that of the adult. Plasma levels fell progressively after birth; whereas neonatal atrial content rose substantially. Plasma AP and NTF were simultaneously elevated in both the maternal and fetal circulation after vasopressin injection of the mother. The fetus can also respond to exogenous stimuli (vasopressin or indomethacin--presumably via ductal closure) and promptly release substantial amounts of peptide into its circulation. Thus, it appears that the AP hormonal system is functional during fetal life and responds avidly to increases in intracardiac pressure as does the mature animal.

Published
1987

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