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Your search keyword '"Xu, Naijin"' showing total 18 results
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18 results on '"Xu, Naijin"'

1. Nitroxoline suppresses metastasis in bladder cancer via EGR1/circNDRG1/miR-520h/smad7/EMT signaling pathway

Author

Ren, Liangliang, primary, Jiang, Minxiao, additional, Xue, Dingwei, additional, Wang, Huan, additional, Lu, Zeyi, additional, Ding, Lifeng, additional, Xie, Haiyun, additional, Wang, Ruyue, additional, Luo, Wenqin, additional, Xu, Li, additional, Wang, Mingchao, additional, Yu, Shicheng, additional, Cheng, Sheng, additional, Xia, Liqun, additional, Yu, Haifeng, additional, Huang, Peng, additional, Xu, Naijin, additional, and Li, Gonghui, additional

Published
2022
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13. Synergistic effects of the immune checkpoint inhibitor CTLA-4 combined with the growth inhibitor lycorine in a mouse model of renal cell carcinoma

Author

Li, Xiezhao, primary, Xu, Peng, additional, Wang, Chongshan, additional, Xu, Naijin, additional, Xu, Abai, additional, Xu, Yawen, additional, Sadahira, Takuya, additional, Araki, Motoo, additional, Wada, Koichiro, additional, Matsuura, Eiji, additional, Watanabe, Masami, additional, Zheng, Junxia, additional, Sun, Pinghua, additional, Huang, Peng, additional, Nasu, Yasutomo, additional, and Liu, Chunxiao, additional

Published
2017
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14. Increased expression of metastasis-associated in colon cancer-1 in renal cell carcinoma is associated with poor prognosis

Author

Jin, Zhong, Xu, Naijin, Guo, Kai, Xu, Peng, Li, Pengju, Zhang, Yiming, Li, Xiezhao, Zheng, Shaobo, Liu, Chunxiao, Xu, Abai, and Huang, Peng

Subjects
Adult, Aged, 80 and over, Male, Middle Aged, Prognosis, Disease-Free Survival, Kidney Neoplasms, Up-Regulation, Survival Rate, Trans-Activators, Humans, Original Article, Female, Neoplasm Metastasis, Carcinoma, Renal Cell, Aged, Transcription Factors
Abstract

Metastasis-associated in colon cancer-1 (MACC1) expression in tumor specimens is an independent prognostic indicator of metastasis, which has recently gained considerable attention in cancer research, due to its overexpression in several types of carcinoma. However, MACC1 expression patterns and its possible role in renal cell carcinoma remain unknown. This study aimed to investigate MACC1 expression in renal cell carcinoma via immunohistochemical analysis and determine the relationship between MACC1 expression and cancer prognosis. Positive MACC1 expression was found to significantly correlate with distant metastasis and TNM stage (P < 0.05). A Kaplan-Meier survival analysis revealed that patients with higher MACC1 expression had a significantly lower disease-free rate (P < 0.05). These results indicate that MACC1 expression is significantly associated with prognosis in patients with renal cell carcinoma. To the best of our knowledge, this is the first study on the significance of MACC1 as a prognostic marker in renal cell carcinoma. MACC1 expression may be a useful target for the development of new therapeutic approaches, including molecular targeted therapeutic agents, for renal cell carcinoma.

Published
2015

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