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Purpose: To study the role of yes-associated protein (YAP) inhibition by verteporfin (VTF) in LPSinduced acute liver injury (ALI) after sepsis.Methods: In vitro, VTF was used to treat LPS-stimulated RAW 267.4 cells. In vivo, LPS was injected to induce sepsis in mice, followed by treatment with VTF. The inflammatory mediators were determined using quantitative real-time polymerase chain reaction (qRT-PCR), immunofluorescence spectroscopy (IF) and immunohistochemical staining (IHC), and the levels of YAP, P53 and ERK were measured by qRT-PCR, WB and IHC. Moreover, liver histology and liver function were examined using HE staining and ELISA respectively.Results: The results showed that VTF reduced YAP expression and inhibited LPS-induced cell activation and inflammatory cytokine production such as IL-6 and IL-1β, by attenuating the expressions of p53 and ERK pathway in macrophages. The levels of AST, AIL and TBiL remarkably decreased in ALI mice after VTF treatment (p < 0.05). Moreover, it was observed that inflammatory mediators, including inducible nitric oxide synthase (iNOS), IL-6 and IL-1β, decreased significantly in VTF treated mice (P < 0.05).Conclusion: VTF plays an antagonistic role in LPS-induced inflammatory response after ALI. Therefore, VTF is a potential medicinal agent for preventing infectious acute liver injury.

Erythropompilus venterisetalis Wu & Ma, sp. nov. Figs 1, 4 (A–C) urn:lsid:zoobank.org:act: 10A825F9-9A88-49C2-BEB5-D9A44684CB96 Material examined. Holotype: CHINA, Yunnan, Xishuangbanna, Mengla, Xishuangbanna Tropical Botanical Garden, teak plantation, ♁, 21°54′N 101°16′E, 508 m, Malaise trap, 13.VII–13.VIII.2021, coll. Yong-sheng Pu (YNAU). Paratypes: CHINA, Yunnan, 13♁, same locality as holotype, 14.VII–14.VIII.2020 (5♁), coll. Yongsheng Pu, 24.IV–31.V.2019 (7♁), coll. Ling Zhao, 14.IX–14.X.2019 (1♁), coll. Ling Zhao; 2♁, Xishuangbanna Prefecture, Wild Elephant Valley, 22°6′N 100°51′E, 783 m, 15.VII.2016, coll. Qing-xia Zhou (YNAU). Diagnosis. The male of the new species is similar to E. thailandensis Pitts & Shimizu, 2021 in having the following characteristics: body black, mesosoma partly orange-red (Figs 1A, 5A), clypeus as broad as LID (Figs 1D, 5D), mid and hind femora with small spines set in pits apicodorsally, and exposed portion of SGP flat, mostly parallel-sided (Fig. 1K); but markedly differs by the characters given in the Table 1. Description. Male. (Measurements of the holotype are given in parentheses). Length: body 4.3–6.3 (5.8) mm; forewing 4.1–5.6 (4.6) mm. Body black; mandible reddish brown at apical 1/4, sometimes subapical yellow brown, basal of mandible with 2–5 (3) brown long setae (Fig. 1D); the following yellow brown to fulvous: palpi, scape, pedicel, F1–F4 beneath, apical 1/7 of fore femora ventrally, fore tibia ventrally, fore tarsus (Figs 1A, 1D); the following orange: posterior margin of pronotum, sides of mesoscutum and posterior margin, mesopleuron, scutellum, metanotum, postnotum, upper half of mesopleuron and posterior rim of propodeum (Figs 1A, 1E). Head: Mandible with one inner tooth, clypeus slightly convex in lateral view, anterior margin nearly straight (Figs 1C, 1D). In frontal view, head 1.19–1.25 (1.25) × as broad as long; vertex slightly convex between eye tops, frontal line fine and inconspicuous; MID large, 0.58–0.62 (0.6) × as broad as TFD; UID: MID: LID = 8.0–9.0 (8): 10: 7.5–8.0 (7.5); clypeus 2.3–2.7 (2.5) × as broad as long, clypeus equal to LID (Fig. 1D). In dorsal view, ocellar area with several sparse punctures, ocelli in obtuse triangle, POD: OOD = 1: 0.7–0.8 (0.73); antennocular line distinctly inclined from antennal base toward eye (Fig. 1B); antenna pointed at apex, F1 2.5–3.1 (3) × as long as thick, 0.5–0.67 (0.61) × as long as UID, length ratios of scape, pedicel, F1–F3 = 11–12 (12): 4: 14–15(15): 15: 14–15 (15) (Figs 1G, 1H). In lateral view, gena short, 0.2–0.3 (0.2) × eye width (Fig. 1C). Mesosoma: Lateral margin of pronotal dorsum, in dorsal view, slightly narrowing anteriorly, pronotum posterior margin slightly arcuate, and conspicuously shorter than mesoscutum (Fig. 1E); in dorsal view, mesoscutum slightly raised, notaulus fine and short anteriorly and medially, parapsidal sulcus reaching nearly 5/6 of mesoscutum; scutellum disc slightly raised, convex above level of mesoscutum; metanotum posterior margin extending at middle and covering postnotum partly; postnotum nearly 1/10 as long as metanotum, depressed medially and narrower than laterally; propodeum, in dorsal view, parallel-sided at anterior half, strongly narrowing at posterior half; in lateral view, gently convex, posterior slope at apical 1/3; propodeal enclosure irregularly reticulate-rugose, and with a pair of subparallel longitudinal carinae medially. Wing: Pterostigma long, 5–6.5 (6) × as long as 2r-rs; marginal cell removed from wing tip by 0.4 × its own length; SMC2: SMC3 = 1: 1.3–1.6 (1.3) on vein M, 1: 0.4–0.6 (0.5) on vein RS, SMC2 broad on vein RS by 1: 0.9–1 (0.9) × its length on vein M, receiving crossvein 1m-cu at basal 0.35–0.55 (0.5); SMC3 narrowed on vein RS by 0.3–0.4 (0.4) × its length on vein M, receiving crossvein 2m-cu at basal 0.5–0.6 (0.55), removed from outer wing margin by 1.4–1.9 (1.5) × its own length. FW crossvein cu-a originating at or slightly beyond fork of vein M+CuA; HW crossvein cu-a arc-like, originating anterior to fork of vein M+CuA (fig. 1F). Legs: Mid and hind femora with 1–2 small spines set in pits apicodorsally; mid tibia dorsally with 3–5 (5) stout brown spines externally and 1–3 (3) brown spines internally, mid tibia ventrally with 0–2 (0) small brown spines externally and 0–2 (1) small brown spines internally; hind tibia dorsally with 5–6 (6) stout brown spines externally and 4–5 (5) stout brown spines internally, hind tibia ventrally with 1–3 (2) small brown spines externally and 1–3 (2) small brown spines internally. Longer spur of hind tibia 0.68–0.72 (0.7) × hind tarsomere 1. Metasoma: Side of S4 and S5, each with tuft of dense, erect and black bristles (Fig. 1J); S6 flat ventrally, posterior margin with arcuate emargination (Fig. 1I); S6 with long blade-like longitudinal keel medially, almost reaching posterior margin (Fig. 1I). SGP and genitalia: SGP, in ventral view, exposed part broad and parallel-sided, translucent and rounded apically, basal sides with weak carina; in lateral view, SGP flat, slightly thickened basally and medially, and with sparse, oblique backward setae, subapically ones long (Fig. 1K). Paramere very short, oval-like (Fig. 4A); volsella narrow in basal 1/3, gradually broadened towards apex, rounded apically, with numerous long setae in apical 1/2 (Fig. 4B); parapenial lobe conspicuously extending apex of volsella, inner margin in apical 1/3 with fine and irregular serrate (Fig. 4C); aedeagus conspicuously longer than parapenial lobe, mostly parallel-sided, apical margin slightly emarginated medially (Fig. 4B). Female. Unknown. Distribution. China (Yunnan). Etymology. The specific name venterisetalis originates from the Latin "venter" (=ventral) and "setalis" (=setae), referring to S4 and S5 of the male with a dense tuft of bristles on the sides., Published as part of Wu, Haiying, Li, Qiang & Ma, Li, 2023, The spider wasp genus Erythropompilus Shimizu & Pitts, 2021 (Hymenoptera Pompilidae) in China, with description of two new species and an updated key to world species, pp. 160-172 in Zootaxa 5244 (2) on pages 162-164, DOI: 10.11646/zootaxa.5244.2.4, http://zenodo.org/record/7656174, {"references":["Shimizu, A., Pitts, J. P., Yoshimura, J. & Wahis, R. (2021) New genus and species of Pompilinae spider wasps from the Oriental Region (Hymenoptera, Pompilidae). Journal of Hymenoptera Research, 84, 339 - 359. https: // doi. org / 10.3897 / jhr. 84.68810"]}

Erythropompilus macroplacoideus Wu & Ma, sp. nov. Figs 2, 3, 4 (D–F) urn:lsid:zoobank.org:act: 1DF79C9F-7F8D-41C7-BDAF-0253B503357F Material examined. Holotype: CHINA, Yunnan, Jinghong, Menghai, Bulang Mountain, &female;, 21°45′N 100°26′E, 1683 m, Malaise trap, 17.V–25.VI.2021, coll. Yong-sheng Pu (YNAU). Paratypes: CHINA, Yunnan, 1&female; 1♁, same locality as holotype, 17.V–21.VI.2018, coll. Ling Zhao (YNAU). Diagnosis. The new species is similar to E. taiwanensis Pitts & Shimizu, 2021 in having the following characteristics: frons strongly convex in profile (Figs 2C, 3C); clypeus less than LID (Figs 2D, 3D); ratio of POD/ OOD larger than 0.85; gena, in dorsal view, thickened, roundly receding posteriorly (Figs 2B, 3B); mid and hind femora without small spines set in pits apicodorsally; but markedly differs by the characters given in the Table 2. Description. Female. (Measurements of the holotype are given in parentheses.) Length: Body 6.0–6.5 (6.5) mm; forewing 5.3–5.6 (5.6) mm. Body black, mandible red-brown at apical 1/3, mandible with 2 brown long setae on basal 2/5 (Fig. 2D), the following brown: beneath of scape, apical 1/6 of fore coxa and femur ventrally, fore tibia ventrally; Mesosoma orange-red, expect for collar, anterior margin of pronotum and lower 1/7 of mesopleuron, sometimes propodeum black (Figs 2A, 2J). Head: Mandible with one inner tooth, clypeus slightly convex in lateral view, anterior margin nearly straight (Fig. 2D). In frontal view, head 1.25 × as broad as long; vertex distinctly convex between eye tops, frontal line fine and inconspicuous; MID large, 0.63–0.64 (0.64) as broad as TFD, UID: MID: LID = 8.5: 10: 7.5–8 (8); clypeus 2.3 × as broad as long, clypeus width less than LID (Fig. 2D). In dorsal view, ocellar area with several sparse punctures, ocelli in obtuse triangle, POD: OOD = 1: 0.9; antennocular line, in dorsal view, distinctly inclined from antennal base toward eye (Fig. 2B); F1 4.2 × as long as thick, 0.68 × as long as UID; length ratios of scape, pedicel, F1–F3 = 12: 5: 18: 16: 15. Flagellomeres with placoid sensilla on inner and external surfaces, external sensilla more than 3/4 each flagellomere, internal F1–F6 less than half of each flagellomere, apical 4 segments less than half of each flagellomere, gena slightly thickened, 0.3 × eye width (Fig. 2C). Mesosoma: Lateral margin of pronotal dorsum, in dorsal view, anteriorly slightly narrower than posterior area, pronotum posterior margin slightly arcuate (Fig. 2E), pronotum conspicuously shorter than mesoscutum; in dorsal view, mesoscutum flat, slightly inclined towards posteriorly, parapsidal sulcus reaching nearly 5/6 of mesoscutum; scutellum disc raised, but not convex above level of mesoscutum; metanotum posterior margin extending at middle and covering partly postnotum, postnotum nearly 1/10 as long as metanotum, depressed medially and narrower than laterally (Fig. 2G). propodeum, in dorsal view, parallel-sided at anterior half, narrowing at posterior half, in lateral view, gently convex, posterior slope at apical 1/3; propodeal enclosure irregularly rugose, and with two longitudinal carinae medially. Wing: Pterostigma long, about 5 × as long as 2r-rs (Fig. 2F); marginal cell removed from wing tip by 0.57 (0.5) × its own length; SMC2: SMC3 = 1: 1.6 on vein M, 1: 0.5 on vein RS; SMC2 broad on vein RS, equal to its length on vein M, receiving crossvein 1m-cu at basal 1/2; SMC3 narrowed on vein RS by 0.3 × its length on vein M, receiving crossvein 2m-cu at basal 0.6, removed from outer wing margin by 1.7 × its own length, crossvein cu-a originating basally to fork of vein M+CuA; HW crossvein cu-a arcute, originating much basal to fork of vein M+CuA. Legs: Mid femur without small spines set in pits apicodorsally, mid tibia dorsally with 4 long brown spines externally and without spines internally, mid tibia ventrally with 2 small brown spines externally and 1 internally respectively; hind tibia dorsally with 6–7 long brown spines externally and 3–5 long brown spines internally, hind tibia ventrally with 1–3 small brown spines externally and 2 small brown spines internally. Longer spur of hind tibia 0.68 × hind tarsomere 1. Male. Differs from female as follows: body length 4.0 mm; forewing 3.8 mm; antenna, clypeus, labrum, mandible basally, all legs and metasoma dark rufous; scape and pedicel ventrally, femur and tibia of fore leg pale brown; pronotum largely, mesoscutum and propodeum black (Fig. 3A). Head: In frontal view, head 1.19 × as broad as long (Fig. 3D); MID large than female, 0.66 as broad as TFD, UID: MID: LID = 9: 10: 8.3; clypeus 2.5 × as broad as long, F1 2.7 × as long as thick, 0.44 × as long as UID; length ratio of scape, pedicel, F I–III = 10: 4: 12: 12: 13 (Fig. 3H), gena narrow, 0.25 × eye width (Fig. 3C). Mesosoma: Notaulus of mesoscutum fine and short anteriorly and medially. Wing: FW inner fasciae light, narrower than that in female, marginal cell removed from wing tip by 0.38 × its own length; SMC2: SMC3 = 1: 1.8 on vein M. Legs: Mid tibia dorsally with 3 short brown spines externally, mid tibia ventrally without spine internally; hind tibia dorsally with 3 short brown spines externally and without spine internally. Metasoma: Side of S4 and S5, each with tuft of sparse, erect and black bristles (Fig. 3J); S6 flat in basal 1/4, with oblique declivity in apical 3/4, posterior margin with inverted V-shaped edge (Fig. 3J); S6 with blade-like longitudinal keel far from posterior margin (Fig. 3J). SGP and genitalia: Exposed portion of SGP narrowing apically, subbasally widest, rounded and translucent apically (Fig. 3K); in lateral view, SGP flat, with clearly triangular-shape ridge basally, and some sparse short setae in basal 2/3 (Fig. 3J). Paramere very short, peg-like (Fig. 4D); volsella narrow at basal 1/2, gradually broadened towards apex, rounded apically, and with several long setae at apical 1/3 (Fig. 4E); parapenial lobe slightly extending apex of volsella, inner margin entirely with fine and irregular serrate (Fig. 4F); aedeagus slightly longer than parapenial lobe, mostly parallel-sided, apical margin conspicuously concave medially (Fig. 4E). Distribution. China (Yunnan). Sex association. Not only were all the female and male specimens collected from the same Malaise trap, but they also have the same pattern and the following common characteristics: ratio of POD: OOD; clypeus Etymology. The name macroplacoideus originates from the Greek word " mac "(=long, large) and " placoideus " (= placoid), referring to the flagellomeres of male with huge placoid sensilla., Published as part of Wu, Haiying, Li, Qiang & Ma, Li, 2023, The spider wasp genus Erythropompilus Shimizu & Pitts, 2021 (Hymenoptera Pompilidae) in China, with description of two new species and an updated key to world species, pp. 160-172 in Zootaxa 5244 (2) on pages 164-169, DOI: 10.11646/zootaxa.5244.2.4, http://zenodo.org/record/7656174, {"references":["Shimizu, A., Pitts, J. P., Yoshimura, J. & Wahis, R. (2021) New genus and species of Pompilinae spider wasps from the Oriental Region (Hymenoptera, Pompilidae). Journal of Hymenoptera Research, 84, 339 - 359. https: // doi. org / 10.3897 / jhr. 84.68810"]}

Genus Erythropompilus Shimizu & Pitts, 2021 Erythropompilus Shimizu & Pitts, 2021 in Shimizu et al. 2021: 341, &female; ♁. Type species: Erythropompilus malaysiensis Pitts & Shimizu, 2021, by original designation. Diagnosis. Both sexes: body usually black or dark rufous, mesosoma sometimes orange-red, FW hyaline with two dark fasciae (Figs 1A, 1F, 3A, 3F, 5A). Vertex crest slightly above uppermost portion of occipital carina (Figs 1B, 3B, 5B); outer orbit sharply grooved; gena narrow (Figs 1C, 3C, 5C); labrum partially exposed (Fig. 1D); postnotum extremely short (Figs 1C, 3C, 5C); in dorsal view, propodeum coarsely and irregularly reticulate-rugose, and with a pair of subparallel longitudinal carinae medially (Fig. 2G); pterostigma large (Figs 1F, 3F); mid and hind tibial spurs ivory-white (Figs 1A, 3A, 5A); protarsus without tarsal comb, all tarsomere 5 without ventral spines, all tarsal claws bifid. Male: flagellomeres with elliptic depressed placoid sensilla (Figs 1G, 1H, 3G, 3H); inner fore tarsal claws conspicuously modified (Fig. 1L); posterolateral of S6 with pair of large and rod-shape hook pointed at middle (Figs 1I, 3I); exposed portion of SGP triangular or arrowhead-shaped, sometimes with long parallel side (Figs 1K, 3K); genitalia with paramere very short (Figs 4A, 4D); parapenial lobe broad and sinuated, pointed at apex (Figs 4C, 4F); volsella with setae, apically rounded; aedeagus broad, parallel-sided for most part (Figs 4B, 4E). Additional characters. Both sexes: mid and hind tibiae ventrally with 2 rows of brown, small spines; all tarsomeres 1–3 with 3 rows of ventral spines, tarsal plantulae present. Male: S6 posteriorly inverted-V-shaped or arcuately emarginated (Figs 1I, 3I); sides of S4 and S5 with more or less setae. Biology. There are currently no records of biological information for this genus. From our observation and collection experience, we know that representatives of the genus are active in grasslands, fields, and sunny places in woodlands and rainforests. Distribution. The Oriental Region: China (Taiwan, Yunnan, Guangxi), Thailand, and Malaysia (Shimizu et al. 2021 and current data). The genus is newly recorded from China mainland., Published as part of Wu, Haiying, Li, Qiang & Ma, Li, 2023, The spider wasp genus Erythropompilus Shimizu & Pitts, 2021 (Hymenoptera Pompilidae) in China, with description of two new species and an updated key to world species, pp. 160-172 in Zootaxa 5244 (2) on page 161, DOI: 10.11646/zootaxa.5244.2.4, http://zenodo.org/record/7656174, {"references":["Shimizu, A., Pitts, J. P., Yoshimura, J. & Wahis, R. (2021) New genus and species of Pompilinae spider wasps from the Oriental Region (Hymenoptera, Pompilidae). Journal of Hymenoptera Research, 84, 339 - 359. https: // doi. org / 10.3897 / jhr. 84.68810"]}

Erythropompilus thailandensis Pitts & Shimizu, 2021 Figs 5 (A–E) Erythropompilus thailandensis Pitts & Shimizu, 2021 in Shimizu et al. 2021: 348, &female; ♁. Holotype, &female;, Thailand, Nakhon Nayok Khao Yai NP near Training Center 2, Pan trap, 5–6.II.2007, Wirat Sukho; deposited in the Queen Sirikit Botanic Gardens, Chiang Mai, Thailand; not examined. Material examined. China: Yunnan: 2&female;, Xishuangbanna Tropical Botanical Garden, rainforest, 21°54′N 101°16′E, 599 m, Malaise trap, 15.V–18.VI.2018, coll. Ling Zhao (YNAU); 1&female;, same locality, habitat as previous, 13.VII– 13.VIII.2021, coll. Yong-sheng Pu (YNAU); 1&female;, same locality, rainforest, 21°54′N 101°16′E, 606 m, Malaise trap, 24.IV–31.V.2019, coll. Ling Zhao (YNAU); 1&female;, same locality, rubber forest, 21°55′N 101°16′E, 543 m, Malaise trap, 25.X–22. XI.2019, coll. Ling Zhao (YNAU); China: Guangxi: 1&female;, Guilin, Xingan, Huajiang, 110°28′E 25°47′N, 26.VI–27.VI.2011, No. 20020143, coll. Zaifu Xu (SCAU). Diagnosis: Female. clypeus as long as LID (Fig. 5D); gena, in dorsal view, thin but roundly receding posteriorly (Fig. 5B); lateral margin of pronotal dorsum, in dorsal view, scarcely narrowing anteriorly (Fig. 5D); mid and hind femora with small spines set in pits apicodorsally (Fig. 5E). Distribution: China (Yunnan, Guangxi) (new record), Thailand (Shimizu et al. 2021)., Published as part of Wu, Haiying, Li, Qiang & Ma, Li, 2023, The spider wasp genus Erythropompilus Shimizu & Pitts, 2021 (Hymenoptera Pompilidae) in China, with description of two new species and an updated key to world species, pp. 160-172 in Zootaxa 5244 (2) on page 169, DOI: 10.11646/zootaxa.5244.2.4, http://zenodo.org/record/7656174, {"references":["Shimizu, A., Pitts, J. P., Yoshimura, J. & Wahis, R. (2021) New genus and species of Pompilinae spider wasps from the Oriental Region (Hymenoptera, Pompilidae). Journal of Hymenoptera Research, 84, 339 - 359. https: // doi. org / 10.3897 / jhr. 84.68810"]}

Antley-Bixler syndrome (ABS) arising from P450 oxidoreductase deficiency (PORD) is a rare, distinct craniosynostosis syndrome, accompanied by ambiguous genitalia and impaired steroidogenesis. It is reported that this disorder is caused by mutations in the P450 oxidoreductase (POR; OMIM #124015) gene via autosomal recessive inheritance. In this study, we performed a molecular analysis to verify the genetic etiology of ABS in an infant. Initially, medical exome sequencing was applied using the parents’ peripheral blood genome DNA. Next, bidirectional Sanger sequencing and quantitative real-time PCR (qRT-PCR) were conducted to confirm the sequencing results. The infant was diagnosed as ABS at birth, with typical midface hypoplasia, craniosynostosis, femoral bowing, radio-ulnar synostosis, and genital anomalies. She died two months later due to severe pneumonia and congenital heart disease. The medical exome sequencing and Sanger sequencing revealed the missense mutation c.1370G>A (p.R457H) in exon 12 of POR was inherited from the father. In addition, the qRT-PCR analysis verified an exon 5 microdeletion in the POR gene of the infant and her mother. While p.R457H is a well-known pathogenic mutation, the POR exon 5 deletion is absent from the public databases. However, it is classified as pathogenic according to the American College of Medical Genetics and Genomics (ACMG) guidelines based on the evidence of PVS1, PM2, and PM3. In conclusion, this infant with ABS carried compound heterozygotic mutations in the POR gene; one was a paternal missense mutation, and the other was a maternal novel microdeletion. The mutations were inherited from the paternal grandfather and maternal grandfather, respectively. This detailed case report enriches our knowledge of the POR mutation spectrum and ABS pathogenesis.

ObjectiveBehavioral intentions to care for patients with infectious diseases are crucial for improving quality of care. However, there have been few studies of the behavioral intentions and factors influencing patient care by clinical nurses during the COVID-19 pandemic. This study aims to explore cognition, attitudes, subjective norms, self-efficacy, and behavioral intentions of clinical nurses while caring for COVID-19 patients and to explore any influencing factors.MethodA cross-sectional survey was conducted of nurses through convenience sampling in southeast China from February 2020 to March 2020. The questionnaire was developed based on the theory of planned behavior and self-efficacy.ResultsA total of 774 nurses completed the survey. Of these, 69.12% (535/774) reported positive behavioral intentions, 75.58% (585/774) reported a positive attitude, and 63.82% (494/774) reported having the confidence to care for patients. However, the lack of support from family and friends and special allowance affected their self-confidence. Attitude, self-efficacy, subjective norms, and ethical cognition were significantly positively correlated with behavioral intentions (r = 0.719, 0.690, 0.603, and 0.546, respectively, all P < 0.001). Structural equation model showed that self-efficacy, attitude, ethical cognition, and subjective norms had positive effects on behavioral intentions (β = 0.402, 0.382, 0.091, and 0.066, respectively, P < 0.01). The total effect of behavioral intentions was influenced by attitude, ethical cognition, self-efficacy, and subjective norms (β = 0.656, 0.630, 0.402, and 0.157, respectively, P < 0.01). In addition, ethical cognition had a positive mediating effect on behavioral intentions (β = 0.539, P < 0.001).ConclusionThe study results indicated that attitude, ethical cognition, and self-efficacy were the main factors influencing nurses' behavioral intention. Efforts should be made to improve nurses' attitude and self-efficacy through ethical education and training to increase behavioral intentions to care for patients with infectious diseases, which will improve the quality of nursing care.

Purpose To identify risk factors predicting spontaneous preterm labor (sPTB) less than 28 weeks after emergency cerclage in the second trimester of pregnancy.Methods 106 cases with Prolapsed membranes in the second trimester of pregnancy who underwent emergency cerclage were collected from July 2019-July 2021 .39 cases who happened sPTB less than 28 weeks were in case group. 67 cases were in control group.Univariate analysis and logistic regression analysis were used to identify the risk factors for sPTB less than 28 weeks after emergency cerclage.Results Among the 106 cases,37cases developed sPTB less than 28 weeks, and the incidence was 36.8%, Univariate analysis showed that positive cervical culture,cervical dilatation,the location of amniotic membranes and histologic chorioamnionitis were related with sPTB(PConclusion The independent risk factors of sPTB less than 28 weeks after emergency cerclage with prolapsed membranes in the second trimester of pregnancy was histologic chorioamnionitis and Amniotic membrane.