122 results on '"Witcher, Michael"'
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2. Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles
3. Achieving clinical success with BET inhibitors as anti-cancer agents
4. Methionine Metabolism Shapes T Helper Cell Responses through Regulation of Epigenetic Reprogramming
5. POGZ promotes homology‐directed DNA repair in an HP1‐dependent manner
6. STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer
7. Oncogenic activity of poly (ADP-ribose) glycohydrolase
8. CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary
9. Genome-wide targeting of the epigenetic regulatory protein CTCF to gene promoters by the transcription factor TFII-I
10. 3D chromatin remodeling potentiates transcriptional programs driving cell invasion
11. Single base-pair resolution analysis of DNA binding motif with MoMotif reveals an oncogenic function of CTCF zinc-finger 1 mutation
12. Abstract 131: The role of p66ShcA in the melanoma oncogenesis process
13. Histone Lysine Demethylase JARID1a Activates CLOCK-BMAL1 and Influences the Circadian Clock
14. POGZ promotes homology‐directed DNA repair in an HP1‐dependent manner
15. p66ShcA potentiates the cytotoxic response of triple negative breast cancers to PARP inhibitors
16. Reprogramming of Nucleotide Metabolism Mediates Synergy between Epigenetic Therapy and MAP Kinase Inhibition
17. Antitumor activity of the dual BET and CBP/EP300 inhibitor NEO2734
18. Small-Cell Carcinoma of the Ovary, Hypercalcemic Type–Genetics, New Treatment Targets, and Current Management Guidelines
19. Retinoic acid modulates chromatin to potentiate tumor necrosis factor alpha signaling on the DIF2 promoter
20. Combination of retinoic acid and tumor necrosis factor overcomes the maturation block in a variety of retinoic acid-resistant acute promyelocytic leukemia cells
21. SWI/SNF-Compromised Cancers Are Susceptible to Bromodomain Inhibitors
22. MNK1/NODAL Signaling Promotes Invasive Progression of Breast Ductal Carcinoma In Situ
23. Oncogenic activity of poly (ADP-ribose) glycohydrolase
24. HIV-1 Employs Multiple Mechanisms To Resist Cas9/Single Guide RNA Targeting the Viral Primer Binding Site
25. Abstract LB-231: Genomic profiling in serial metastatic colorectal tumors identifies copy number alterations and spatio temporal intra-patient heterogeneity profiles associated with clinical response. Q-CROC-01: NCT00984048
26. Epigenetic Silencing of the p16INK4a Tumor Suppressor Is Associated with Loss of CTCF Binding and a Chromatin Boundary
27. Competition between translation initiation factor eIF5 and its mimic protein 5MP determines non-AUG initiation rate genome-wide
28. CTCF facilitates DNA double-strand break repair by enhancing homologous recombination repair
29. Abstract A12: CTCF facilitates DNA double-strand break repair by homologous recombination
30. Anticancer Properties of Phyllanthus emblica (Indian Gooseberry)
31. Insights into a novel nuclear function for Fascin in the regulation of the amino-acid transporter SLC3A2
32. Haploinsufficiency of the ESCRT Component HD-PTP Predisposes to Cancer
33. Chemotherapy reduces PARP1 in cancers of the ovary: implications for future clinical trials involving PARP inhibitors
34. Analysis of changes to mRNA levels and CTCF occupancy upon TFII-I knockdown
35. Anticancer Properties ofPhyllanthus emblica(Indian Gooseberry)
36. Competition between translation initiation factor eIF5 and its mimic protein 5MP determines non-AUG initiation rate genome-wide.
37. Gallotannin Imposes S Phase Arrest in Breast Cancer Cells and Suppresses the Growth of Triple-Negative Tumors In Vivo
38. Abstract 4378: Poly(ADP-ribose)glycohydrolase (PARG) is a novel therapeutic target in breast cancer.
39. Abstract 5515: In vivo efficacy of the PARG inhibitor Gallotannin against triple negative breast cancer.
40. Functional and Molecular Characterization of the Role of CTCF in Human Embryonic Stem Cell Biology
41. Is There an Epigenetic Component Underlying the Resistance of Triple-Negative Breast Cancers to Parp Inhibitors?
42. Interaction of the anti-apoptotic protein BAG-1 with the vitamin D receptor.
43. Synergy between all-trans retinoic acid and tumor necrosis factor pathways in acute leukemia cells
44. Gallotannin Imposes S Phase Arrest in Breast Cancer Cells and Suppresses the Growth of Triple-Negative Tumors In Vivo.
45. Epigenetic Silencing of the p16INK4a Tumor Suppressor Is Associated with Loss of CTCF Binding and a Chromatin Boundary
46. Synergy between all-transretinoic acid and tumor necrosis factor pathways in acute leukemia cells
47. 4X4 FORUM: February No. 313.
48. HIV-1 employs multiple mechanisms to resist Cas9/sgRNA targeting the viral primer binding site.
49. Gallotannin Imposes S Phase Arrest in Breast Cancer Cells and Suppresses the Growth of Triple-Negative Tumors In Vivo.
50. p66ShcA potentiates the cytotoxic response of triple-negative breast cancers to PARP inhibitors.
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