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4. Studies on Sorption and Release of Doxycycline Hydrochloride from Zwitterionic Microparticles with Carboxybetaine Moieties.

Author

Racovita, Stefania, Trofin, Marin-Aurel, Vasiliu, Ana-Lavinia, Avadanei, Mihaela, Loghin, Diana Felicia, Mihai, Marcela, and Vasiliu, Silvia

Subjects
SORPTION, GENTIAN violet, DOXYCYCLINE, WATER purification, MOIETIES (Chemistry)
Abstract

The aim of this study was to examine the use of zwitterionic microparticles as new and efficient macromolecular supports for the sorption of an antibiotic (doxycycline hydrochloride, DCH) from aqueous solution. The effect of relevant process parameters of sorption, like dosage of microparticles, pH value, contact time, the initial concentration of drug and temperature, was evaluated to obtain the optimal experimental conditions. The sorption kinetics were investigated using Lagergren, Ho, Elovich and Weber–Morris models, respectively. The sorption efficiency was characterized by applying the Langmuir, Freundlich and Dubinin–Radushkevich isotherm models. The calculated thermodynamic parameters (ΔH, ΔS and ΔG) show that the sorption of doxycycline hydrochloride onto zwitterionic microparticles is endothermic, spontaneous and favorable at higher temperatures. The maximum identified sorption capacity value is 157.860 mg/g at 308 K. The Higuchi, Korsmeyer–Peppas, Baker–Lonsdale and Kopcha models are used to describe the release studies. In vitro release studies show that the release mechanism of doxycycline hydrochloride from zwitterionic microparticles is predominantly anomalous or non-Fickian diffusion. This study could provide the opportunity to expand the use of these new zwitterionic structures in medicine and water purification. [ABSTRACT FROM AUTHOR]

Published
2024
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9. The Influence of Beverages on Resin Composites: An In Vitro Study

Author

Gradinaru, Irina, primary, Vasiliu, Ana Lavinia, additional, Bargan, Alexandra, additional, Checherita, Laura Elisabeta, additional, Ciubotaru, Bianca-Iulia, additional, Armencia, Adina Oana, additional, Istrate, Bogdan, additional, Dascalu, Cristina Gena, additional, and Antohe, Magda Ecaterina, additional

Published
2023
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12. Hydroxypropyl Cellulose/Pluronic-Based Composite Hydrogels as Biodegradable Mucoadhesive Scaffolds for Tissue Engineering

Author

Filip, Daniela, primary, Macocinschi, Doina, additional, Zaltariov, Mirela-Fernanda, additional, Ciubotaru, Bianca-Iulia, additional, Bargan, Alexandra, additional, Varganici, Cristian-Dragos, additional, Vasiliu, Ana-Lavinia, additional, Peptanariu, Dragos, additional, Balan-Porcarasu, Mihaela, additional, and Timofte-Zorila, Mihaela-Madalina, additional

Published
2022
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20. Technological issues of the shell-tempered ware from Gârcina (Neamț County, Romania).

Author

MĂȚĂU, Florica, MUNTEANU, Roxana, NICA, Valentin, PINTILEI, Mitică, VASILIU, Ana-Lavinia, and STANCU, Alexandru

Subjects
MINERALOGY, X-ray diffraction, ENERGY dispersive X-ray spectroscopy
Abstract

Copyright of Studia Antiqua et Archeologica is the property of Studia Antiqua et Archeologica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2018

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