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A queilite actínica (QA) é uma lesão comum do lábio inferior causada principalmente pela exposição com frequência elevada ou crônica à radiação solar. É considerada uma lesão cancerizável, onde o diagnóstico precoce pelo profissional é de extrema importância para o bom prognóstico do caso visto que a QA muitas vezes é a lesão precursora do carcinoma espinocelular de lábio inferior. Na área da saúde, é importante realizar um atendimento integral do paciente, criando uma interseção entre sua queixa principal e as necessidades que ele apresenta para que se consiga reestabelecer a saúde geral. O presente estudo visa apresentar um caso clínico de um paciente do gênero masculino, 38 anos de idade, que buscou o serviço odontológico para o tratamento de uma disfunção temporomandibular mas que, ao seu atendimento integralizado, percebeu-se a presença de uma lesão nodular em ventre lingual e de uma mácula leucoplásica em vermelhão de lábio inferior. Houve indicação para biópsia excisional da lesão nodular e de biópsia incisional para a lesão leucoplásica. Após o diagnóstico de neuroma traumático em língua e de queilite actínica em lábio inferior, com a confirmação histopatológica, foi realizada uma biópsia excisional simples. Após a remoção da lesão o paciente retornou para remoção de sutura e para proservação do caso, onde apresentou boa recuperação.

As malformações vasculares são anomalias estruturais dos vasos sanguíneos sem proliferação endotelial, estão presentes ao nascimento e persistem ao longo da vida. Elas podem ser categorizadas de acordo com o tipo de vaso envolvido (capilar, venoso, arteriovenoso) e de acordo com as características hemodinâmicas (baixo fluxo ou alto fluxo). Possuem uma etiologia variável, como fatores químicos, mutações genéticas ou alterações relacionadas a síndromes, fluxo sanguíneo, resistência da parede vascular e trauma. Neste caso, a malformação vascular apresentada pela paciente tem relação com o trauma em mucosa jugal devido a atividade parafuncional presente. Atividade parafuncional refere-se a qualquer atividade que não seja considerada funcional, como apertar e/ou ranger os dentes durante o dia e/ou à noite, mascar chicletes, morder bochecha, lábios e língua. Algumas destas atividades podem ser responsáveis por concorrer para a Disfunção Temporomandibular (DTM), pois promovem hiperatividade muscular mastigatória. Dor muscular, restrição de abertura de boca, sensação de plenitude auricular, zumbido na orelha e vertigem foram alguns dos sintomas apresentados pela paciente. Diante desse quadro, além de tratar a malformação vascular com uma combinação de escleroterapia e excisão cirúrgica, foi também tratado o quadro disfuncional, para seu controle e resolução além da prevenção de recidiva da lesão, com a utilização de placa miorrelaxante combinada com a realização de exercícios fisioterápicos, mostrando-se eficazes, contendo a sintomatologia, restringindo a atividade parafuncional e reduzindo o trauma na mucosa.

Introdução: O osteoma é um tumor benigno, de crescimento lento e indolor, composto de osso maduro que pode ser compacto e/ou esponjoso, afetando geralmente os ossos gnáticos. Objetivo: mostrar um caso clínico de osteoma trabecular, que afetou região edêntula do elemento 36 em paciente do sexo feminino, feoderma de 36 anos onde, há aproximadamente 3 anos, o elemento fora extraído devido à destruição por cárie e não feito nenhum tratamento reabilitador. Material e método: Realizado exame clínico e tomográfico, sendo neste observado em corpo mandibular, na região edêntula do elemento 36, uma imagem hiperdensa irregular, mas bem delimitada de aproximadamente 5 cm em seu maior diâmetro, circunscrita por área hipodensa. A interrelação desses exames levou às hipóteses diagnósticas de osteoma, osteoblastoma e odontoma complexo, que, após biópsia excisional e análise histopatológica, se confirmou o diagnóstico de osteoma. Resultado: Realizada a interrelação clínica, imagenológica e histopatológica, obteve-se o diagnóstico de osteoma trabecular. Conclusão: a remoção completa da lesão foi importante para a confirmação diagnóstica e configurou seu tratamento, sendo raros os casos recidivantes.

Introdução: A doença de Paget (DP) ou osteíte deformante é uma doença osteometabólica benigna, caracterizada pela reabsorção e deposição anormal e anárquica de osso, este osso é menos resistente e mais suscetível a fraturas. Objetivo: mostrar caso clínico de manifestação atípica de DP que afetou área de seio maxilar (maior intensidade) e outras regiões como cóccix, tubérculo ilíaco direito e esquerdo e articulação sacroilíaca direita e esquerda, numa paciente do sexo feminino de 63 anos que queixava dor em hemi-maxila esquerda com aumento progressivo local desde a juventude. Esta acometia região dos dentes remanescentes ipsilaterais 23 e 24 com doença periodontal crônica grave. Material e método: Por exames de imagem observou hiperdensidade que preenchia quase toda a extensão do seio maxilar esquerdo com áreas de hipodensidade e na cintilografia apresentava maior captação de radiofármaco também nesta localização. Para elucidação diagnóstica, cujas hipóteses contemplavam, além de DP, também tumor marrom do hiperparatiroidismo e osteossarcoma, foram solicitados exames laboratoriais: TSH, creatinina, PTH, T3, T4, fosfatase alcalina, albumina, microalbumina, TGP, cálcio sérico, aldolase e calcitonina que não apresentaram nenhuma alteração, sendo indicada a biopsia incisional para análise histopatológica e conclusão diagnóstica. Resultado: Feita a interrelação das características clínicas, laboratoriais, imagenológicas e exame histopatológico, obteve-se diagnóstico de DP. Conclusão: Após diagnóstico, paciente foi encaminhada para tratamento reumatológico. O tratamento ordinariamente transcorre com o uso de bifosfonatos para redução da remodelação óssea, sendo amplamente usado o ácido zoledrônico além de analgésicos para o controle da dor.

A mucocele é considerada uma lesão comum da mucosa oral, que resulta da ruptura de um ducto de glândula salivar e extravasamento de mucina para dentro dos tecidos moles adjacentes. Frequentemente encontrada no lábio inferior, o presente trabalho descreverá um caso de mucocele em mucosa do palato, considerada um região atípica, para muitos autores. Paciente do gênero feminina, 51 anos de idade, melanoderma, foi encaminhada para a Policlínica odontológica da UEA, com hipótese diagnóstica de hemangioma. Na anamnese, paciente relatou tempo de evolução de 5 meses, ausência de sintomatologia dolorosa, negou possuir hábitos de sucção e não ter traumatizado a área durante a alimentação ou escovação, além de não possuir hábito tabagista, etilista ou fazer uso de prótese, e sem histórico de doença sistêmica. Diante das informações clinicas, estabelecemos hipóteses diagnósticas: Carcinoma Mucoepidermóide e Mucocele. O diagnóstico foi confirmado através de biopsia excisional da lesão e exame histopatológico. Portanto, mesmo se tratando de uma lesão simples, podemos nos deparar com dificuldade diagnóstica, quando a localização da lesão é incomum. Entretanto, cabe ressaltar a importância de uma análise diferencial do caso, que para o presente trabalho, foi de grande importância para se chegar ao diagnóstico e assim proporciona um tratamento eficaz para a paciente.

Sialolitíases de pequenas proporções localizadas na porção terminal do ducto podem ser difíceis de serem eliminadas de forma passiva, causando problemas ao paciente como episódios de dor e desconforto, podendo evoluir para complicações como infecção ou retenção mucosa. O presente trabalho relata um caso de sialolitíase de uma paciente de 35 anos. Ao exame clínico constatou-se a presença de uma elevação nodular na região de carúncula sublingual, formato cilíndrico, indolor e móvel à palpação, endurecida, coloração amarelada, aumento de volume sensível no pescoço durante algumas refeições, e evolução de sete meses. Ao exame tomográfico, foi possível observar a presença de uma massa hiperdensa na região de assoalho bucal. Inicialmente foi realizado uma ordenha associada a colocação de cone de guta percha, mas não se obteve sucesso. O tratamento realizado foi a remoção cirúrgica do sialólito sem necessidade de síntese associado ao uso tópico de Mud Oral juntamente com a orientação da ordenha para estimulação do fluxo salivar. A hipótese diagnóstica para esta lesão foi de sialolitíase e a mesma foi confirmada através da análise histopatológica. A paciente, continuou em acompanhamento pós-operatório durante 3 semanas, durante este período, a mesma não desenvolveu nenhuma sintomatologia relevante, sendo dispensada após 21 dias. Portanto, diante das possibilidades clínicas e situação da paciente optou-se por métodos mais conservadores e menos invasivos associados a orientações de cuidados pós-operatórios para que se obtivesse uma rápida recuperação e um bom prognóstico.

O carcinoma espinocelular (CEC) é a neoplasia maligna mais comum da cavidade oral, sendo seus agentes etiológicos principais: o álcool, tabaco e o Papilomavirus Humano (HPV) de alto risco, porém, existem outras possibilidades etiopatogênicas ainda não amiudadas pela ciência. Este trabalho relata caso de paciente do gênero feminino, 48 anos, não tabagista, não etilista e sem sinal de infecção pelo vírus HPV, com queixa de lesão nodular em ventre lingual. Relatou hábito de “chupar a língua” desde tenra idade, boca seca e ardência bucal há alguns meses e, ao exame físico, apresentou ordenha negativa das glândulas parótidas, baixa coleta nas sublinguais e submandibulares. Apresentava sinais de comprometimento muscular cervical, massetérico e, por conseguinte, bucinatório, condição que pode concorrer fisicamente para estenose do ducto parotídeo e redução da secreção parotídea. Após diagnóstico de CEC, a paciente foi submetida a tratamento cirúrgico, radio e quimioterápico. Para o controle do hábito parafuncional, provavelmente relacionado à lesão que evoluiu para o CEC, foram realizados: uso de dispositivo interoclusal, fisioterapia e crioterapia com prescrição de saliva artificial e creme reparador para as lesões mucosas, decorrentes da hipo/assialia. Consideramos que a associação do trauma crônico, fator modificador clássico, resultante da atividade parafuncional e a redução do fluxo salivar promovida- entre outras razões orgânicas primárias, prévias ao tratamento radio e quimioterápico- pelo potencial estreitamento do ducto de Stenon em razão da disfunção mastigatória, como promotora da perda de homeostasia local e não controle de iniciadores endógenos e/ou exógenos, concorreram para o desenvolvimento da condição neoplásica.

Diante das neoformações malignas de cabeça e pescoço, o carcinoma mucoepidermoide apresenta-se como uma das manifestações de grande ocorrência, sendo a região do palato a mais envolvida. Podendo o tratamento resultar em mutilações na cavidade oral, ocasionando comunicação bucosinusal, a qual poderá ser restaurada por intermédio de próteses obturadoras. O objetivo do presente trabalho é relatar um caso clínico de confecção de prótese obturadora palatina oca em paciente portador de carcinoma mucoepidermoide após maxilectomia parcial, e, a técnica de moldagem facial prévia a tratamento cirúrgico de recidiva. Paciente buscou atendimento odontológico, mencionando apresentar sua prótese total obturadora mal adaptada devido o tempo de uso. Seu plano de tratamento, consistiu na confecção da prótese obturadora pela técnica da clonagem e prótese parcial removível convencional. Após alguns meses, detectou-se clinicamente a recidiva da lesão, onde foi realizado novo procedimento cirúrgico, o qual não obteve sucesso. Então optou-se por outra abordagem, desenvolvendo a moldagem facial, pois uma cirurgia mais invasiva seria necessária, podendo trazer consequências na face. A paciente encontrava-se em tratamento radioterápico, sendo a nova intervenção médica escolhida. A prótese obturadora é uma alternativa eficaz na reabilitação de pacientes submetidos a ressecções cirúrgicas, as quais resultaram em mutilações. Sendo assim, a escolha pela técnica da clonagem com algumas modificações, nesse caso além do custo-benefício, as etapas clínicas e laboratoriais foram reduzidas e como consequência a substituição da prótese foi mais rápida eficaz. Além disso, é de grande relevância o papel dessa reabilitação na reintegração do indivíduo no meio biopsicossocial, o restabelecimento da função, estética e conforto.

Introduction: Necrotizing sialometaplasia (NS) is a rare locally destructive inflammatory benign disease that commonly affects the minor salivary glands. It is frequently associated with the glands located in the posterior portion of the hard and soft palates. Low-level laser therapy (LLLT), also called photobiomodulation therapy (PBMT), has been deemed a substantial method for the regenerative wound process. Case Presentation: A 32-year-old male patient was referred with a chief complaint of two asymptomatic crater-like ulcers measuring approximately 1.5 cm wide on the right side of the hard and soft palates, and another measuring 0.3 cm wide on the left side of the hard palate. The lesion had two weeks of evolution followed by a previous infectious "sore throat" event that kept the patient hospitalized for 4 days. A clinical diagnosis of NS was made. LLLT was applied during 2 sessions per week, favoring the total wound healing within 2 weeks. At 3 months of clinical followup, the patient did not present any complication or relapse and was thus released. Conclusion: This is, to our knowledge, the first clinical report of LLLT applied for the management of NS. Large palatal ulcers caused by NS usually have long healing periods. The shortened healing period observed in this case encourages the inclusion of LLLT in any treatment protocol for similar lesions.

Pediatric mandibular tumors present an aggressive biological behavior and difficult diagnosis. A wide range of odontogenic and nonodontogenic tumors comprise the spectrum of these lesions. We report a case of a 1-year-old male child patient showing facial asymmetry symptomatic of an expansive lesion extending throughout the body and ramus of the left hemimandible with a diameter of 8 cm. The histopathological report suggested a high-grade mucoepidermoid carcinoma (MEC), recommending further immunohistochemical investigation of the ectomesenchymal or neuroectodermal origin of the tumor cells. The patient evolved with extensive bilateral pleural effusion followed by metastasis in the middle third of the right humerus, and died 2 months after the first biopsy procedure by acute renal failure with tubular necrosis, before a final inconclusive immunohistochemical report was reached. The lack of resources for less-favored regions of Brazil impairs rapid biomolecular examinations such as immunohistochemical resulting in delay of appropriate therapeutic procedures.

Made available in DSpace on 2020-12-12T01:12:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-05-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Aim: To evaluate the morphology and impact of root canal preparation in maxillary incisors with palatogingival grooves (PGG). Methodology: Twenty extracted human maxillary incisors with PGG were subjected to macroscopic analysis and scanning electron microscopy analysis (SEM). The following characteristics of the PGG were evaluated: depth, point of origin in the cingulum, extension and position on the lingual surface. Furthermore, the presence of calculus, communications between the root canal system and the PGG, and root resorptions were investigated. The root canals were subsequently instrumented with K-files of three consecutive sizes. The teeth were sectioned, and the axial plane of each tooth section was imaged using SEM before and after instrumentation. The distance between the root canal walls and the PGG was calculated according to the location. Additionally, the distance between canal walls and cementum was measured at three different sites, to verify if instrumentation influenced dentine removal on a specific wall in teeth with PGG. Statistical analysis was performed using the Mann–Whitney or Student’s t-test (P 0.05). Conclusions: Palatogingival grooves were characteristically deep and originated from the distal margin of the cingulum. Although it has been associated with a thinner root wall, root canal preparation did not influence the thickness of the specific wall in the maxillary incisors with PGG. Oral Pathology and Oral Medicine Dental School of Amazonas State University Endodontics School of Dentistry São Paulo State University (Unesp) Cariology Restorative Sciences and Endododontics University of Michigan Restorative Dentistry School of Dentistry Federal University of Minas Gerais Oral Pathology Bauru Dental School University of São Paulo Endodontics School of Dentistry São Paulo State University (Unesp) FAPESP: 03/10721-5

Background Oral leukoplakia is the most common potentially malignant lesion, the etiology of this change is still uncertain which makes it difficult to predict when this will undergo malignant transformation. Recent studies have examined the involvement of mast cells in this process, it is believed that these cells through the release of pro-angiogenic factors influence the processing mechanism of such lesions through promoting angiogenesis. It was the objective of this study to evaluate the inflammatory process in oral leukoplakia comparing it to a non-cancerous lesion correlating the intensity of mast cells with inflammatory infiltrate and vascularization in these lesions. Methods A total of 20 selected cases divided into two groups, oral leukoplakia and inflammatory fibrous hyperplasia (IFH). Histochemical Technique of Toluidine Blue was applied to enhance mast cells and histomorphometry for quantifying mast cells, blood vessels and inflammatory cell infiltration by capturing digital images of the samples and analysis software Image Java version 1.48v. Mast cells and blood vessels were counted in 10 different areas and the intensity of the inflammatory infiltrate was measured in three areas. The analysis of variance (ANOVA) was used for between-group variation, a P value of 0.05 for statistical significance. Results It was observed a reduction in the concentration of mast cells in oral leukoplakia compared fibrous inflammatory hyperplasia. In contrast to the concentration of blood vessels were present in higher concentrations in the Oral leukoplakia lesions. The inflammatory infiltrate in most cases was considered scarce, except in a case where that IFH was intense and a case of moderate inflammatory infiltrate in oral leukoplakia. Conclusions The results showed reduction in the number of mast cells in the oral leukoplakia and greater intensity in the inflammatory process in the IFH, suggesting a possible carcinogenic influence in the microenvironment oral leukoplakia.

Made available in DSpace on 2022-05-01T11:07:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-04-01 Fundação de Amparo à Pesquisa do Estado do Amazonas The current research aims to perform a comparative evaluation of vegetable matter involved lesions with oral parasitic infections found in oral mucosa, presenting histochemical methods to differentiate their microscopic similarities. Eight cases were selected out of a sample of 1.975 reports from a single Oral and Maxillofacial Pathology Service of the author's institution from 2012 to 2019. Specimens were examined by hematoxylin and eosin staining (HE), periodic acid-Schiff (PAS) staining, Gomori–Grocott staining, Ziehl–Neelsen staining, Giemsa, and mucicarmine staining. Microscopic analysis included fluorescence, polarized light, and confocal microscopy. Microscopically, in HE coloration, hookworm eggs showed as eosinophilic. Inflammatory multinucleated giant cells and lymphocytes, were usually related to the nematode eggs, forming an intense inflammatory infiltrate. Biofluorescent properties of eggs and larvae revealed to be sensitive in the detection of parasitic structures contrasting with the inflamed connective tissue. Vegetable presence was confirmed by polarized light microscopy and it was found to be associated with microbial biofilms. Confocal microscopy has showed to be an excellent method for morphotype differentiation of parasitic eggs. Parasitic infection and vegetable matter displayed similarities in the inflammatory response, but the latter can rot and agglomerate biofilms. The microscopic diagnosis of such infections requires the interpretation of challenging morphological features since the parasites are usually sectioned and mixed with an inflammatory reaction. These histochemical approaches proved to be excellent to distinguish both lesions. School of Health Sciences Amazonas State University, AM Faculty of Dentistry São Paulo State University, SP Amazon Hematology and Hemotherapy Foundation, AM Faculty of Dentistry São Paulo State University, SP

Made available in DSpace on 2021-06-25T10:57:44Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01 Aim: To investigate the effects of liver fibrosis (LF) on the pro-inflammatory mediators and periapical bone resorption of apical periodontitis (AP) in rats. Methodology: Forty male Wistar rats were distributed into four groups: C – control, AP – rats with AP, LF – rats with LF, AP + LF – rats with AP and LF. LF was induced by carbon tetrachloride administration for 8 weeks and surgical bile duct ligation for 4 weeks; AP was induced in the teeth of rats by dental pulp exposure to the oral environment for 30 days. Jaws and livers were removed after euthanasia. Haematoxylin and Eosin (H&E) and Picrosirius Red (PSR) staining were used to confirm fibrosis in the livers. The jaws were analysed using H&E staining, immunohistochemical assays of interleukin (IL)-1β, IL-6 and tumour necrosis factor-alpha (TNF-α). Student’s t-test and Mann–Whitney’s U-test were used for statistical analysis (P

The purpose of this study was to investigate the tissue reaction stimulated by BaSO4 - and Bi2 O3 -containing White MTA Angelus, in comparison with Bi2 O3 -containing white Portland cement, and white ProRoot MTA. Thirty-six adult male Wistar rats (Rattus norvegicus), weighing between 250 and 300 g, were distributed into three groups (n = 12) in accordance with the period of sacrifice (15, 30, and 60 days). Four polyethylene tubes filled with the tested cements were implanted into the dorsum of each rat. Lateral wall of the tubes served as the negative control. After the experimental periods, the animals were euthanized by overdose of pentobarbital anesthetic solution, and the specimens were prepared for microscopic analysis under ×50, ×100, and ×400 magnifications. Inflammatory scores (0-3) were used to grade the tissue reaction. Data were analyzed by the Kruskal-Wallis test and Dunn's test for individual comparisons (p .05). The Portland group had moderate inflammatory reaction at the final period of analysis, which was statistically different when compared to the other groups (p

Made available in DSpace on 2022-04-29T08:31:20Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Introduction: Periodontitis, a complex infectious disease that may lead to irreversible loss of periodontium, is considered a predisposing agent for developing insulin resistance due to the release of inflammatory mediators, showing a bilateral relationship with diabetes mellitus. The investigation of periodontal disease requires a clinical approach and complete intraoral radiographs, even with increasing concerns about radiation exposure. Thus, this study assesses pixel linear analysis accuracy using digital radiography via Digora® in detecting alveolar bone destruction in diabetic rats with periodontal disease. Methodology: 40 rats were divided into groups (n = 10): control (C), rats with periodontal disease (PD), experimental diabetic rats (ED), experimental diabetic rats with periodontal disease (ED-PD). Diabetes was induced by streptozotocin and periodontal disease by periodontal ligature. After 30 days, maxillae bone destruction was obtained by linear analysis of vertical bone loss using digital radiography and then assessed by micro-CT and histology. Data were analyzed by ANOVA and Tukey's test (p < 0.05). Results: Radiographic, micro-CT and histological analysis presented accurate and similar results. PD and ED-PD groups showed higher bone destruction than C and ED groups (p < 0.05). Moreover, the ED-PD group had higher bone loss than the PD group (p < 0.05). Conclusion: The pixel linear analysis via digital radiography was an accurate, low-cost alternative in detecting alveolar bone loss in this rat model. Micro-CT and histological analysis may also be used to obtain linear measures to assess and compare periodontal bone destruction in diabetic rats. Department of Preventive and Restorative Dentistry Endodontic Section School of Dentistry São Paulo State University (Unesp) Department of Basic Science School of Dentistry São Paulo State University (Unesp) Department of Dentistry Endodontics and Dental Materials School of Dentistry University of São Paulo – USP Division of Endodontics University of Minnesota School of Dentistry Department of Cariology Restorative Sciences and Endodontics University of Michigan Department of Periodontics University Center São Lucas School of Dentistry Department of Oral Pathology and Oral Medicine Dental School of Amazonas State University Dental Assistance Center for Disabled Persons (CAOE) of the São Paulo State University (Unesp) School of Dentistry Department of Endodontics State University of Northern Paraná (UENP) School of Dentistry Department of Preventive and Restorative Dentistry Endodontic Section School of Dentistry São Paulo State University (Unesp) Department of Basic Science School of Dentistry São Paulo State University (Unesp) Dental Assistance Center for Disabled Persons (CAOE) of the São Paulo State University (Unesp) School of Dentistry

A hiperplasia palatina por câmara de sucção (HPCS) ou hiperplasia do palato está associada ao uso de próteses totais mucosuportada superiores com câmara de vácuo. A Câmara de sucção é uma depressão que os protéticos ou práticos realizavam na porção interna da prótese total superior em sua porção central, com o objetivo de promover uma maior estabilidade. O objetivo deste trabalho foi relatar o diagnóstico de um caso clínico odontológico de uma paciente com Hiperplasia Palatina por câmara de sucção, atendida na Disciplina de Diagnóstico Bucal, do curso de Odontologia, da Universidade do Estado do Amazonas evidenciando os aspectos clínicos gerais e bucais. Foi feito apenas o diagnóstico da lesão já que a paciente estava de viagem marcada para outro estado, não contribuiu para a troca das próteses superior e inferior. Ademais foi deixado bem claro, que deveria ser feito uma cirurgia para remoção da lesão, e também, a confecção de uma nova prótese, já que a prótese em questão não era mais condizente para o uso. O cirurgião-dentista deve ser crítico ao exame clínico e a queixa principal do paciente, bem como, nas diferentes formas de tratamentos das lesões bucais.Descritores: Hiperplasia; Palato; Prótese Total.ReferênciasTrindade MGF, Oliveira MC, Prado JP, Santana LLP. Lesões associadas à má adaptação e má higienização da prótese total. Id on line Rev Mult Psic. 2008;12(42):956-68.Alves DLM. Cândida spp e prótese dentária removível: interações de relevância clínica: revisão bibliográfica [dissertação]. Porto: Universidade Fernando Pessoa/Faculdade de Ciências da Saúde; 2009.Azenha MR, Handem RH. Tratamento clínico e cirúrgico de hiperplasia palatina causada por câmara de sucção: relato de caso clínico. Rev Port Estomatol Med Dent Cir Maxilofac. 2008;49(3):145-47.De Carli JP, Bernabé DG, Kawata L, Moraes NP, Silva SO. Hiperplasia palatina por câmara de sucção tratada por meio da eletrocirurgia: relato de dois casos clínicos. RFO UPF. 2006;11(2):81-5.Peters R, Bercini F, Azambuja TWF. Hiperplasia inflamatória: Revisão de literatura e apresentação de caso clínico cirúrgico. Rev Fac Odont Porto Alegre. 1996;37:7-8.Neville BW, Damm DD, Alen CM, Bouquot JE. Patologia oral e maxilofacial. Rio de Janeiro: Elsevier; 2009.Regezi JA, Sciubba JJ, Jordan RCK. Patologia oral: correlações clinicopatológicas. 5. Ed. Rio de Janeiro: Elsevier; 2008.Ferreira KE, Rodrigues CRT. Prótese total mediata em paciente com lesão hiperplásica causada por câmara de sucção: relato de caso clínico. Braz J Surg Clin Res. 2013-2014;5(1):39-46.Catão CDS, Ramos INC, Silva NJM, Duarte SMO, Batista AUD, Dias AHM. Eficiência de substâncias químicas na remoção de biofilme em próteses totais. Rev Odontol UNESP. 2007;36(1):53-60.Kazuo SD, Ferreira UCS, Justo KD, Rye OE, Shigueyuki UE. Higienização em prótese parcial removível. Rev Odontol Univ Cid São Paulo. 2008; 20(2):168-74.Gonçalves LFF, Silva Neto DR, Carlo HL, Bonan RF, Batista AUD. Higienização de próteses totais e parciais. R bras ci Saúde. 2011;15(1):87-94.

Made available in DSpace on 2019-10-06T16:52:09Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-12-01 Pilomatrixoma is considered a rare benign tumor arising from the hair follicle, most common in the head and neck region, but it is rarely diagnosed on a clinical basis. This report describes a new case of giant pilomatrixoma in a 36-year-old female patient. The nodule was localized in the preauricular area on the right side, appearing as a slow-growing, fixed, painless, with a hardened consistency, unusual giant (4.5 cm). A cone-beam computed tomography (CBCT) examination showed a slightly hyperdense lesion, and fine-needle aspiration cytology (FNAC) revealed peripheral blood and mononucleated inflammatory cells. After enucleation of lesion, a diagnosis of pilomatrixoma was confirmed. The differential diagnosis of pilomatrixoma is broad, because its characteristics also can be found in other lesions common to the head and neck. Thus, a lesion in the head and neck, adherent to the skin, and well demarcated, mainly in the young and in females, should be suspected as pilomatrixoma. Oral Pathology and Oral Medicine Amazonas State University Maxilofacial Surgery Amazonas State University Maxilofacial Surgery Amazonas State University Maxilofacial Surgery Residency Endodontics School of Dentistry São Paulo State University (Unesp) Periodontics School of Dentistry University Center São Lucas Endodontics School of Dentistry São Paulo State University (Unesp)

Inflammatory pseudotumors are a group of lesions of unknown etiology that mimic clinically and radiographically neoplasms. In the maxilla, inflammatory pseudotumors are presented with bone alterations of erosion, remodeling, and sclerosis. The diagnosis is of exclusion, where multiple biopsies are required. The present study aims to report the case of a male patient who presented with increased volume in the left maxillary region, with diagnosis after total left maxillectomy being inflammatory pseudotumor. The patient did not present recurrences with 3 years of preservation and underwent by multidisciplinary treatment with esthetic and functional rehabilitation with the preparation of a bucomaxilo prosthesis. Despite presenting some suggestive clinical features, the inflammatory pseudotumor has a difficult and of exclusion diagnosis, where multiple biopsies are required. They are lesions that simulate clinically and radiographically neoplasms. If it is surgically accessible, the treatment of choice is complete surgical resection.

Objective This study aimed to determine the correlation between the vascular mast cells and inflammatory changes in the potentially malignant disorders, compared to the oral squamous cell carcinoma (OSCC) in varying degrees of dysplasia. Materials and Methods Thirty samples were selected: 10 of OSCC, 10 of oral leukoplakia, and 10 of actinic keratosis. The toluidine blue technique was used on the mast cells, and hematoxylin and eosin were used for analyzing the lymphocytes, mitosis, and vessels. The quantification was performed using the ImageJ software after obtaining the images by light microscopy with a × 40 objective. Analysis of variance with p < 0.05 was considered for statistical significance. Results Mast cells (p < 0.0158), vessels (p < 0.9431), lymphocytes (p < 0.0001), and mitoses (p < 0.0009) were found in OSCC. In potentially malignant disorders, a lower density of these structures and a higher concentration of mitosis in the actinic keratosis were observed. Conclusion The results showed evidence of a positive correlation between mast cells and vascularization in the OSCC, suggesting the aggression of the disease. Intense inflammatory infiltrate indicates that other molecular events are involved in the carcinogenesis process, and further studies are necessary for a better understanding of it.

Facial cosmetic procedures are on increasing demand, for plastic surgeons and dental professionals now-a-days. New techniques applied for the renewal offacial contours have become the first treatment option before surgical corrections. This case report highlights some of the risks related to such procedures, reporting a case of a painful fluctuating nodule in the midline of the vestibular sulcus, extending towards the upper lip. The patient mentioned a 2-year history of progression of the lesion. The nodule was 0.8 cm wide, well defined, with normal colour. The excisional biopsy was proposed with initial suspect of pleomorphic adenoma, or other soft tissue tumour. Microscopic evaluation of the excised lesion revealed a foreign body granuloma caused by multiple spherules of transparent synthetic material of uniform diameter, identified as Polymethylmetacrylate (PMMA). The patient then recalled that he underwent an aesthetic procedure of rhinoplasty with facial filling that he did not correlate with the symptoms.

Background Sialadenoma papilliferum is a benign rare condition of salivary glands showing a characteristic papillary growth of the ductal epithelium that ends up being confused with more frequent lesions of the oral cavity. Objectives: To perform a bibliometric analysis of all articles about Sialadenoma papilliferum in the oral cavity and to add a singular case report of Sialadenoma in the lower lip. Material and methods A total of 36 publications referring to Sialadenoma papilliferum in the oral cavity from the PubMed platform was reviewed. The specific data were collected, and a bibliometric analysis was performed using Microsoft Excel. The results obtained were then compared with this new case report. Results The people most affected with sialadenoma were white males at the average age of 56. The lesion was asymptomatic, usually white or red, with an average size of 1.4 cm, and the palate was by far the most affected site. The majority of the lesions were excised, and only two cases indicated recurrence. Conclusions With surgical removal, Sialadenoma papilliferum has a favorable prognosis and no further treatment is required. Due to few recorded cases of recurrence, a long follow-up period is recommended to ensure that the lesion does not redevelop. Key words:Sialadenoma papilliferum, salivary gland, oral cavity, bibliometric analysis.

O mioespasmo é uma alteração involuntária sustentada por mediação central. É uma alteração em que o músculo permanece contraído por alguns segundos, minutos ou mesmo dias e também é frequentemente observado durante tratamento em que necessitam de sessões prolongadas, como, por exemplo, tratamentos endodônticos de molares. Depois de determinado tempo, o paciente mostra instabilidade para manter a boca aberta, apresentando episódios de fechamento repentinos. Mioespasmos são facilmente reconhecidos pela disfunção estrutural que produzem. Descrever o diagnóstico de um caso de mioespasmo em paciente com mordida aberta anterior, otalgia e dor na própria ATM. A paciente M.M.S.R, 33 anos, gênero feminino, cor parda, compareceu ao atendimento na Policlínica da UEA para exame estomatológico de rotina. Durante a anamnese a paciente relatou que sentia dores de cabeça, dor de ouvido, apertamento dos dentes durante a noite e possuía o elemento 46 fraturado, relatou também ter ido ao dentista fazer a restauração do elemento dental 46 há aproximadamente um ano e que, passado alguns dias do procedimento começou a ter dores de cabeça frequentemente, porém a paciente relatou ser muito estressada. Por conseguinte, a etiologia dos mioespasmos não tem sido bem documentada. É provável que muitos fatores se combinem para promover o mioespasmo. Condições musculares locais certamente aparecem para criar mioespasmos: as dores de cabeça, de ouvido, dor facial, má oclusão aguda, dentre outros. Compete ao cirurgião-dentista diagnosticar e tratá-las em conjunto com outras especialidades.Descritores: Espasmo; Mialgia; Mordida Aberta; Otite; Transtornos da Articulação Temporomandibular.

Introduction Ranulas are lesions that affect the salivary glands, and they are generally treated by excision; however, they can recur in some cases where the gland is not removed and they may progress to acute suppurative sialadenitis, yet such cases are rare, especially in children. Aims To report clinical management of occurrence of acute suppurative sialadenitis secondary to excisional biopsy of ranula in a child. Case report An 11-year-old female patient was diagnosed with ranula where excisional biopsy was performed. Subsequently, the patient developed infection, suggesting Ludwig's angina, after reevaluation, she was diagnosed with acute suppurative sialadenitis in the right mandibular gland; during the follow-up period, antibiotic therapy was introduced. Conclusion The close relationship of the biopsy site with the submandibular space and other structures of the neck required the completion of antibacterial prophylaxis associated with preoperative care, transoperative care, and postoperative care to combat opportunistic infections and their subsequent complications. Clinical Significance Suppurative sialadenitis and its subsequent complications may be considered, although rare, as a complication in cases of ranula. How to cite this article Pinheiro TN, Arid J, Maciel AP, Machado AFM, Monteiro ML, de Oliveira Daltoé M, de Carvalho FK. Acute Suppurative Sialadenitis Secondary to Excisional Ranula Biopsy in Child. Int J Experiment Dent Sci 2016;5(2):123-126.

Objective: This study aims at studying the influence of hypercementosis over root and root canal morphology us-ing different methods of observation (clearing technique, radiography, stereomicroscopy and optical microscopy). Methods: 130 teeth were selected for morphological com-parative evaluation; all teeth were previously radiographed and stereomicroscopically evaluated. Out of these, 60 teeth with hypercementosis and 30 without it were selected for clearing technique evaluation. The analysis was based on aspects such as: type of hypercementosis; root canal num-ber and configuration; root surface and presence of apical foramen and apical deltas. The remaining 20 teeth with hy-percementosis were microscopically compared to 20 teeth with normal root formation by means of the Hematoxylin and Eosin (H.E.) staining technique, so as to study the ce-mentum deposition pattern and morphological aspects of the root canal. The evaluation was performed by two ex-aminers and submitted to Kappa agreement test. The data obtained was compared through non-parametric Kruskal-Wallis one-way analysis of variance test, and the Dunn test was applied for individual comparisons. Results: The root clearing examination showed higher frequency of club shaped hypercementosis (65%) followed by focal hyperce-mentosis (35%). Teeth with hypercementosis showed sig-nificant increase in the presence of apical deltas (53.3%). A higher frequency of root canal constrictions (55%), and changes in the original root canal path (46.6%) were also observed. Microscopic evaluation supports the influence of hypercementosis over the morphological characteristics of root apical third formation. Conclusions: These findings show the existence of a complex root canal anatomy at the apical third of teeth with hypercementosis, which may hinder root canal treatment.Keywords: Hypercementosis. Dental pulp cavity. Endodontics.

Aim To evaluate the distribution of bacteria in teeth with pulp necrosis and apical granuloma. Materials and methods Thirty-two extracted teeth with pulp necrosis and apical granulomas and 16 cases of isolated apical granulomas were sectioned and stained with Hematoxylin and Eosin (H&E) and Brown-Brenn staining for microscopic evaluation. The specimens were observed as to the location and distribution of bacteria involved in the process of pulp necrosis and their relationship with the periapical tooth structures and soft tissues. Results Stainable Gram-positive and Gram-negative bacteria were found in the entire root canal system. Bacterial biofilms were detected in 81.2% of cementum root canal, 46.8% in apical delta, 65.6% at the apical surface and 79.2% of the granulomas above all the specimens. Bacteria and bacterial biofilms were present in the entire root canal system of the infected teeth with apical granulomas. Conclusion Our findings suggest that bacterial infections can reach inaccessible areas to instrumentation. How to cite this article Ribeiro FC, Consolaro A, Pinheiro TN. Bacterial Distribution in Teeth with Pulp Necrosis and Apical Granuloma. Int J Experiment Dent Sci 2013;2(2):86-91.

Objectives Dental amalgam discharge in the wastewater stream is a potential source of mercury (Hg) that may contaminate the soil, water and wildlife, once released without safety measures. This study aimed the total Hg accumulation in fish Carassius auratus comparing different water environments: Water from the Tietê river basin close to the metropolitan area of Bauru, Brazil; tap water contaminated with 0.5 gm/l load of dental amalgam and tap water was used as control. Study design Fish were kept in glass aquaria, each water environment consisted of 25 specimens. The inner organs and muscles were sampled at 1 hour and 28 days for total Hg accumulation analysis. Also, water samples were analyzed at 1 hour, 7, 14, 21 and 28 days through cold vapor atomic absorption spectrometry. Results Only the fish kept at water from the Tietê river and contaminated tap water had Hg detected on its sampled tissues. The highest median levels were found in inner organs: 12.36 mg/kg–Tietê river and 262.64 mg/kg–contaminated tap water. The lowest median concentrations were found in muscles: 0.13 mg/kg–Tietê river and 0.54 mg/kg–contaminated tap water. Conclusion These findings alert to the potential environmental risks of dental amalgam waste discharge. How to cite this article Pinheiro TN, Consolaro A, Sakuma A, Buzzo ML, de Carvalho MS, Duran MC. Mercury Accumulation in Fish: The Potential Effect of Dental Amalgam Wastewater. Int J Experiment Dent Sci 2012;1(2):75-80.

O presente estudo avaliou uma casuística constituída por 144 transplantes dentários autógenos realizados em 128 pacientes, submetidos a controles periódicos de 6 meses a 23 anos. O objetivo do trabalho foi avaliar a influência de fatores clínicos e radiográficos no índice de sucesso dos transplantes realizados. Clinicamente avaliou-se a alteração na coloração dentária, vitalidade pulpar, comprometimento periodontal, tipo dentário transplantado e sítio receptor. Radiograficamente foram avaliados a presença ou não de reabsorção radicular, anquilose dento-alveolar, alterações no compartimento pulpar, complementação do desenvolvimento radicular, presença de periapicopatia persistente e relação coroa/raiz. Os dados foram coletados, analisados e submetidos a cálculos estatísticos pertinentes. As reabsorções dentárias, a anquilose dentoalveolar, a proporção coroa/raiz, a presença de periapicopatia persistente, o desenvolvimento de bolsa periodontal profunda e a mobilidade dentária destacaram-se de forma significante estatisticamente P

Chronic sclerosing sialadenitis or Kuttner tumor is an unusual chronic inflammatory disease of the salivary gland that mimics a malignant neoplasm clinically because of presentation as a hard mass. The diagnosis can only be made histologically and is an underrecognized entity. Recent studies have shown important features that characterizes the disease mainly as an autoimmune reaction. The aim of this work is to report a case of a 40-year-old man, presenting with a three-year history of a painless, moderate sublingual mass related to a partial edentulism of the teeth 36 and 37. Functional evaluation revealed an awkward misplacement of the mass into the edentulous site. Clinical and radiographic procedures revealed a decreased salivary flow and no signs of remarkable pain or sialolithiasis. Sublingualectomy was performed and histopathological examination confirmed the presence of nonobstructive chronic sclerosing sialadenitis of the sublingual gland. The possible autoimmune reaction triggered by hidden (sequestered) antigens exposed by chronic masticatory trauma is discussed.

The present paper draw the attention of clinicians to investigate multiple slices of the computed tomography (CT) scan looking for a safe diagnosis of the so-called Garrè's osteomyelitis (GO) of jaws, a not uncommon disease characterized by astonishing bone growth. We report a case involving the left mandible of a 12-year-old girl presenting with a bony enlargement at left mandible. Initial examination revealed carious process of tooth 36 with radiographic apical rarefaction. However, we need to take care with this diagnosis because other aggressive diseases may cause bone enlargement mimicking GO. We observed here that careful examination of CT slices must be elucidative. In the present case, we observed the formation of a hypodense channel between periapical disease and the bone growth, through CT, thus supporting the pathophysiologic conditions for GO and allowing a safer decision to make the intervention restricted to tooth.

Objective: To evaluate the effectiveness of the NaviTip FX, brush-covered irrigation needle, in removing calcium hydroxide from the root canal. Study Design: Thirty single-rooted teeth were randomly divided into three groups: A - irrigation with a hypodermic needle inserted as far as possible without binding and activation with #30 K-type file; B - Irrigation with a hypodermic needle without activation; C - irrigation with NaviTip FX needle. Sodium hypoclorite 1% was used in irrigation. The root canals were examined trough scanning electron microscopy. Calcium hydroxide removal was recorded at 1, 5, and 10mm from the working length (WL) and the data were analysed using one-way ANOVA test (p

Made available in DSpace on 2013-08-12T17:49:59Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-01-01 Made available in DSpace on 2013-09-30T18:29:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-01-01 Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20T13:43:26Z No. of bitstreams: 0 Made available in DSpace on 2014-05-20T13:43:26Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-01-01 Objective: The aim of this study was to compare two methodologies used in the evaluation of tissue response to root-end filling materials in rats. Material and Methods: Forty rats were divided into 4 groups: in Groups I and II (control groups), empty polyethylene tubes were implanted in the extraction site and in the subcutaneous tissue, respectively; in Groups III and IV, polyethylene tubes filled with ProRoot MTA were implanted in the extraction site and in the subcutaneous tissue, respectively. The animals were killed 7 and 30 days after tube implantation, and the hemi-maxillas and the capsular subcutaneous tissue, both with the tubes, were removed. Specimens were processed and evaluated histomorphologicaly under light microscopy. The scores obtained were analyzed statistically by the Kruskal-Wallis test (p

The purpose of this study was to evaluate morphological characteristics of teeth with hypercementosis that are relevant to endodontic practice. Twenty-eight extracted teeth with hypercementosis had their root apexes analyzed by scanning electron microscopy (SEM). The teeth were divided according to tooth groups and type of hypercementosis. The following aspects were examined under SEM: the contour and regularity of the root surface; presence of resorption; presence and number of apical foramina, and the diameter of the main foramen. The progression of club shape hypercementosis was directly associated with the presence of foramina and apical foramen obstruction. Cases of focal hypercementosis presented foramina on the surface, even when sidelong located in the root. Circular cementum hyperplasia form was present in 2 out of 3 residual roots, which was the highest proportion among the tooth types. The detection of a large number of foramina in the apical third of teeth with hypercementosis or even the possible existence of apical foramen obliteration contributes to understand the difficulties faced during endodontic treatment of these cases.