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3. Theory of Chiral Transport in Carbon Nanotubes

Author

Noro, Masaki, Tanaka, Junya, Yokoyama, Takehito, and Murakami, Shuichi

Subjects
Condensed Matter - Mesoscale and Nanoscale Physics, Condensed Matter - Materials Science
Abstract

Based on the similarity between the chiral nanotube and the classical solenoid, we study chiral transport along the circumferential direction in a carbon nanotube. We calculate the chiral conductivity, representing a circumferential current induced by an electric field along the nanotube axis for various chiralities of carbon nanotubes. We find that the chiral conductivity in a chiral nanotube is in general non zero, and oscillates as a function of the Fermi energy. This oscillating behavior is attributed to the subband structure of the nanotubes and the warping of the Fermi surfaces., Comment: 10 pages, 5 figures

Published
2021

5. Some properties of doubly-degenerate stars

Author

Yoshida, Shin'ichirou and Tanaka, Junya

Subjects
Astrophysics - High Energy Astrophysical Phenomena, General Relativity and Quantum Cosmology
Abstract

We investigate critical masses of and circular geodesics around doubly-degenerate stars (DDSs) which are composed of cold nuclear matter as well as cold Fermionic dark matter (DM). We here consider asymmetric dark Fermion with self-interaction as a DM candidate. These stars have core-envelope structures and are categorized into baryon-enveloped and DM-enveloped, according to the composition of their envelope. It is seen that the baryon-enveloped and DM-enveloped classes have their own critical masses determined mainly by the dominant component in their envelope. For a typical parameter sets, we see that a balanced mixture of two species may lead to smaller masses than if the either of the species is dominant. We also show that for a highly DM-enveloped case circular orbits in the vacuum region terminates at the innermost stable circular orbit (ISCO) in vacuum, but circular orbits of smaller radius are possible in the DM-envelope forming a gap between the ISCO and the inner orbits., Comment: 8 pages, 12 figures

Published
2020

6. Quantitative measurement of peritumoral concentrations of glutamate, N-acetyl aspartate, and lactate on magnetic resonance spectroscopy predicts glioblastoma-related refractory epilepsy

Author

Nakamura, Yawara, Inoue, Akihiro, Nishikawa, Masahiro, Ohnishi, Takanori, Yano, Hajime, Kanemura, Yonehiro, Ohtsuka, Yoshihiro, Ozaki, Saya, Kusakabe, Kosuke, Suehiro, Satoshi, Yamashita, Daisuke, Shigekawa, Seiji, Watanabe, Hideaki, Kitazawa, Riko, Tanaka, Junya, and Kunieda, Takeharu

Published
2022
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9. Chloride intracellular channel protein 2 is secreted and inhibits MMP14 activity, while preventing tumor cell invasion and metastasis

Author

Ozaki, Saya, Umakoshi, Akihiro, Yano, Hajime, Ohsumi, Shota, Sumida, Yutaro, Hayase, Erika, Usa, Eika, Islam, Afsana, Choudhury, Mohammed E., Nishi, Yusuke, Yamashita, Daisuke, Ohtsuka, Yoshihiro, Nishikawa, Masahiro, Inoue, Akihiro, Suehiro, Satoshi, Kuwabara, Jun, Watanabe, Hideaki, Takada, Yasutsugu, Watanabe, Yuji, Nakano, Ichiro, Kunieda, Takeharu, and Tanaka, Junya

Published
2021
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10. In-plane electric polarization of bilayer graphene nanoribbons by interlayer bias voltage

Author

Okugawa, Ryo, Tanaka, Junya, Koretsune, Takashi, Saito, Susumu, and Murakami, Shuichi

Subjects
Condensed Matter - Mesoscale and Nanoscale Physics, Condensed Matter - Materials Science
Abstract

We theoretically show that an interlayer bias voltage in the AB-stacked bilayer graphene nanoribbons with armchair edges induces an electric polarization along the ribbon. Both tight-binding and ab initio calculations consistently indicate that when the bias voltage is weak, the polarization shows opposite signs depending on the ribbon width modulo three. This nontrivial dependence is explained using a two-band effective model. A strong limit of the bias voltage in the tight-binding model shows either one-third or zero polarization, which agrees with topological argument., Comment: 11 pages, 9 figures, accepted by PRL

Published
2015
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13. 10027-CBMS-3 POSTOPERATIVE EPILEPTOGENICITY IN GLIOBLASTOMA ARE ACHIEVED AS THE RESULT OF INTERACTIVE FLUCTUATIONS OF GLUTAMATE AND STEM CELL MARKER

Author

Kusakabe, Kosuke, primary, Inoue, Akihiro, additional, Ohnishi, Takanori, additional, Nakamura, Yawara, additional, Ohtsuka, Yoshihiro, additional, Nishikawa, Masahiro, additional, Yano, Hajime, additional, Tanaka, Junya, additional, Watanabe, Hideaki, additional, and Kunieda, Takeharu, additional

Published
2023
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17. Identification of CD44 as a Reliable Biomarker for Glioblastoma Invasion: Based on Magnetic Resonance Imaging and Spectroscopic Analysis of 5-Aminolevulinic Acid Fluorescence

Author

Inoue, Akihiro, primary, Ohnishi, Takanori, additional, Nishikawa, Masahiro, additional, Watanabe, Hideaki, additional, Kusakabe, Kosuke, additional, Taniwaki, Mashio, additional, Yano, Hajime, additional, Ohtsuka, Yoshihiro, additional, Matsumoto, Shirabe, additional, Suehiro, Satoshi, additional, Yamashita, Daisuke, additional, Shigekawa, Seiji, additional, Takahashi, Hisaaki, additional, Kitazawa, Riko, additional, Tanaka, Junya, additional, and Kunieda, Takeharu, additional

Published
2023
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24. Chloride Intracellular Channel Protein 2 Promotes Microglial Invasion: A Link to Microgliosis in the Parkinson’s Disease Brain

Author

Choudhury, Mohammed E., primary, Ozaki, Saya, additional, Miyaue, Noriyuki, additional, Matsuura, Taisei, additional, Mikami, Kanta, additional, Islam, Afsana, additional, Kubo, Madoka, additional, Ando, Rina, additional, Yano, Hajime, additional, Kunieda, Takeharu, additional, Nagai, Masahiro, additional, and Tanaka, Junya, additional

Published
2022
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26. Rearing in an Enriched Environment Ameliorates the ADHD-like Behaviors of Lister Hooded Rats While Suppressing Neuronal Activities in the Medial Prefrontal Cortex

Author

Utsunomiya, Ryo, primary, Mikami, Kanta, additional, Doi, Tomomi, additional, Choudhury, Mohammed E., additional, Jogamoto, Toshihiro, additional, Tokunaga, Naohito, additional, Ishii, Eiichi, additional, Eguchi, Mariko, additional, Yano, Hajime, additional, and Tanaka, Junya, additional

Published
2022
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28. Microglial re-modeling contributes to recovery from ischemic injury of rat brain: A study using a cytokine mixture containing granulocyte-macrophage colony-stimulating factor and interleukin-3

Author

Matsumoto, Shirabe, primary, Choudhury, Mohammed E., additional, Takeda, Haruna, additional, Sato, Arisa, additional, Kihara, Nanako, additional, Mikami, Kanta, additional, Inoue, Akihiro, additional, Yano, Hajime, additional, Watanabe, Hideaki, additional, Kumon, Yoshiaki, additional, Kunieda, Takeharu, additional, and Tanaka, Junya, additional

Published
2022
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32. Surgical stress quickly affects the numbers of circulating B-cells and neutrophils in murine septic and aseptic models through a β2adrenergic receptor

Author

Nishioka, Ryutaro, primary, Nishi, Yusuke, additional, Choudhury, Mohammed E., additional, Miyaike, Riko, additional, Shinnishi, Ayataka, additional, Umakoshi, Kensuke, additional, Takada, Yasutsugu, additional, Sato, Norio, additional, Aibiki, Mayuki, additional, Yano, Hajime, additional, and Tanaka, Junya, additional

Published
2022
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36. Chloride Intracellular Channel Protein 2 Promotes Microglial Invasion: A Link to Microgliosis in the Parkinson's Disease Brain.

Author

Choudhury, Mohammed E., Ozaki, Saya, Miyaue, Noriyuki, Matsuura, Taisei, Mikami, Kanta, Islam, Afsana, Kubo, Madoka, Ando, Rina, Yano, Hajime, Kunieda, Takeharu, Nagai, Masahiro, and Tanaka, Junya

Subjects
PARKINSON'S disease, CHLORIDE channels, BRAIN diseases, MICROGLIA, RECOMBINANT proteins
Abstract

Activated microglia potentially cause neurodegeneration in Parkinson's disease (PD). Matrix metalloproteinase (MMP)-9 plays a crucial role in the pathogenesis of PD, but the modulator of microglial release of MMP-9 remains obscure. Given the modulatory effect of chloride intracellular channel protein 2 (CLIC2) on MMPs, we aimed to determine the role of CLIC2 in regulating microglial MMP expression and activation. We found that CLIC2 is expressed in microglia and neurons in rat brain tissue and focused on the function of CLIC2 in primary cultured microglia. Exposure to recombinant CLIC2 protein enhanced microglial invasion activity, and its knockdown abolished this activity. Moreover, increased activation of MMP-9 was confirmed by the addition of the CLIC2 protein, and CLIC2 knockdown eliminated this activation. Additionally, increased expression of CLIC2 was observed in PD-modeled tissue. In conclusion, CLIC2 increases MMP-9 activity in the microglia, which are involved in PD pathogenesis. [ABSTRACT FROM AUTHOR]

Published
2023
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37. Surgical stress quickly affects the numbers of circulating B-cells and neutrophils in murine septic and aseptic models through a β2 adrenergic receptor.

Author

Nishioka, Ryutaro, Nishi, Yusuke, Choudhury, Mohammed E., Miyaike, Riko, Shinnishi, Ayataka, Umakoshi, Kensuke, Takada, Yasutsugu, Sato, Norio, Aibiki, Mayuki, Yano, Hajime, and Tanaka, Junya

Subjects
ADRENERGIC receptors, ADRENERGIC agonists, B cells, SYMPATHETIC nervous system, MYELOID cells, BETA adrenoceptors, ALPHA adrenoceptors
Abstract

Sepsis is a pathology accompanied by increases in myeloid cells and decreases in lymphoid cells in circulation. In a murine sepsis model induced by cecum ligation and puncture (CLP), increasing numbers of neutrophils and decreasing levels of B-cells in circulation are among the earliest changes in the immune system. However, to date, the mechanisms for these changes remain to be elucidated. The study here sought to elucidate mechanisms underlying the changes in the leukocyte levels after CLP and also to determine what, if any, role for an involvement of the sympathetic nervous system (SNS). Here, male C57/BL6 mice were subjected to CLP or sham-CLP (abdominal wall incised, but cecum was not punctured). The changes in the number of circulating leukocytes over time were then investigated using flow cytometry. The results showed that a sham-CLP led to increased polymorphonuclear cells (PMN; most of which are neutrophils) and decreased B-cells in the circulation to an extent similar to that induced by CLP. Effects of adrenergic agonists and antagonists, as well as of adrenalectomy, were also examined in mice that underwent CLP or sham-CLP. Administering adrenaline or a β2 adrenergic receptor agonist (clenbuterol) to mice 3 h before sacrifice produced almost identical changes to as what was seen 2 h after performing a sham-CLP. In contrast, giving a β2 adrenergic receptor antagonist ICI118,551 1 h before a CLP or sham-CLP suppressed the expected changes 2 h after the operations. Noradrenaline and an α1 adrenergic receptor agonist phenylephrine did not exert significant effects. Adrenalectomy 24 h before a sham-CLP significantly abolished the expected sham-CLP-induced changes seen earlier. Clenbuterol increased splenocyte expression of Cxcr4 (a chemokine receptor gene); adrenalectomy abolished sham-CLP-induced Cxcr4 expression. A CXCR4 antagonist AMD3100 repressed the sham-CLP-induced changes. From these results, it may be concluded that sepsis-induced activation of the SNS may be one cause for immune dysfunction in sepsis – regardless of the pathogenetic processes. [ABSTRACT FROM AUTHOR]

Published
2022
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42. CD44 expression in the tumor periphery predicts the responsiveness to bevacizumab in the treatment of recurrent glioblastoma

Author

Nishikawa, Masahiro, primary, Inoue, Akihiro, additional, Ohnishi, Takanori, additional, Yano, Hajime, additional, Kanemura, Yonehiro, additional, Kohno, Shohei, additional, Ohue, Shiro, additional, Ozaki, Saya, additional, Matsumoto, Shirabe, additional, Suehiro, Satoshi, additional, Nakamura, Yawara, additional, Shigekawa, Seiji, additional, Watanabe, Hideaki, additional, Kitazawa, Riko, additional, Tanaka, Junya, additional, and Kunieda, Takeharu, additional

Published
2021
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46. Vacuum End Effector Equipped with an Expansion and Contraction Mechanism Using a Wound Thin Metal Plate.

Author

Tanaka, Junya

Subjects
*METALS, *ANIMAL exoskeletons, *WOUNDS & injuries, *TUBES, *SHELVING (Furniture)
Abstract

We propose a vacuum end effector with an expansion and contraction mechanism to realize a picking task for objects placed in a narrow space, such as a shelf. The proposed expansion and contraction mechanism consists of a tube and exoskeleton structure and is characterized by the use of a thin metal plate wound about itself to form a tubular exoskeleton. Expansion and contraction motions were realized by connecting the tube to a linear motion mechanism. The expansion and contraction mechanism can be easily extended by elastic force. In addition, the shape of the expansion and contraction mechanism is created by winding a thin metal plate around a predetermined axis, which ensures high rigidity even in the extended state. Even when an object to be picked from a shelf is located behind other objects, the end effector can efficiently hold the object because of its elongated shape and ability to freely change the position of the suction pad using a direction-changing linkage and the expansion and contraction mechanism. The developed end effector weighs about 1.46 kg and can carry a load of 0.56 kg when extended to 150 mm. Verification of the mechanism confirmed that the developed end effector is useful because it can perform the expected object-picking operation. [ABSTRACT FROM AUTHOR]

Published
2022
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48. Thermoelectric Properties of InxFeCo3Sb12 Consisting Mainly of In-Filled p-Type Skutterudites

Author

Yuji Ohishi, Jungmin Kim, Misato Takahashi, Ken Kurosaki, Shinsuke Yamanaka, Hiroaki Muta, Seongho Choi, and Tanaka Junya

Subjects
Materials science, Mechanical Engineering, chemistry.chemical_element, 02 engineering and technology, 010402 general chemistry, 021001 nanoscience & nanotechnology, Condensed Matter Physics, Thermoelectric materials, Microstructure, 01 natural sciences, 0104 chemical sciences, chemistry, Mechanics of Materials, Thermoelectric effect, General Materials Science, Composite material, 0210 nano-technology, Indium
Published
2017
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49. CBMS-04 SIGNIFICANT ROLE OF HYPOXIA IN THE EXPRESSION AND FUNCTION OF OSTEOPONTIN IN CD44-HIGHLY EXPRESSED GLIOMA STEM-LIKE CELLS IN TUMOR PROGRESSION OF GLIOBLASTOMA

Author

Nishikawa, Masahiro, primary, Inoue, Akihiro, primary, Ohtsuka, Yoshihiro, primary, Ozaki, Saya, primary, Matsumoto, Shirabe, primary, Suehiro, Satoshi, primary, Yano, Hajime, primary, Kanemura, Yonehiro, primary, Tanaka, Junya, primary, Ohnishi, Takanori, primary, and Kunieda, Takeharu, primary

Published
2019
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