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7. Psychometric testing of the Functional Assessment of Cancer Therapy/Gynecologic Oncology Group—Neurotoxicity (FACT/GOG-Ntx) subscale in a longitudinal study of cancer patients treated with chemotherapy

Author

Cheng, Hui Lin, Lopez, Violeta, Lam, Simon Ching, Leung, Anthony Kwun To, Li, Yu Chung, Wong, Kam Hung, Au, Joseph Siu Kie, Sundar, Raghav, Chan, Alexandre, De Ng, Terrence Rong, Suen, Lorna Kwai Ping, Chan, Choi Wan, Yorke, Janelle, and Molassiotis, Alex

Subjects
Health Services and Systems, Nursing, Health Sciences, Cancer, Adult, Aged, Antineoplastic Agents, Female, Humans, Longitudinal Studies, Male, Middle Aged, Neoplasms, Peripheral Nervous System Diseases, Psychometrics, Quality of Life, Reproducibility of Results, Surveys and Questionnaires, Chemotherapy, Peripheral neuropathy, FACT, GOG-Ntx, EORTC QLQ-CIPN20, Responsiveness, Confirmatory factor analysis, FACT/GOG-Ntx, Public Health and Health Services, Health Policy & Services, Health services and systems, Public health
Abstract

BackgroundThe aim of this study was to evaluate the psychometric properties of the Functional Assessment of Cancer Therapy/Gynecologic Oncology Group-Neurotoxicity (FACT/GOG-Ntx) subscale in a longitudinal study of cancer patients treated with chemotherapy.MethodsPatients were assessed with the FACT/GOG-Ntx subscale, European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Chemotherapy-Induced Peripheral Neuropathy Scale 20 (EORTC QLQ-CIPN20), National Cancer Institute -Common Terminology Criteria for Adverse Events (NCI-CTCAE), and light touch test using 10 g monofilament for up to ten assessment points from baseline (prior to initiation of first chemotherapy), after the end of each cycle (up to 6 cycles, 3 weeks per cycle), and at 6, 9, and 12 months after starting chemotherapy. Psychometric analyses included internal consistency reliability, convergent validity, factorial validity, sensitivity to change and responsiveness (minimal clinically important difference, MCID).ResultsCronbach's alpha coefficients of the FACT/GOG-Ntx subscale were 0.82-0.89 across assessment points. The subscale strongly correlated with the EORTC QLQ-CIPN20 (r = 0.79-0.93) but low-to-moderately correlated with the NCI-CTCAE sensory (rs = 0.23-0.45) and motor items (rs = 0.15-0.50) as well as the monofilament test (rs = 0.23-0.47). The hypothesized 4-factor structure of the FACT/GOG-Ntx subscale was not confirmed at assessment points (χ2/df = 2.26-8.50; all P

Published
2020

21. Efficacy and feasibility of a 12-week Tai Chi training for the prophylaxis of episodic migraine in Hong Kong Chinese women: A randomized controlled trial

Author

Xie, Yao Jie, primary, Tian, Longben, additional, Hui, Stanley Sai-Chuen, additional, Qin, Jing, additional, Gao, Yang, additional, Zhang, Dexing, additional, Ma, Tongyu, additional, Suen, Lorna Kwai Ping, additional, Wang, Harry Haoxiang, additional, Liu, Zhao-Min, additional, Hao, Chun, additional, Yang, Lin, additional, and Loke, Alice Yuen, additional

Published
2022
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27. Semi-Individualized Acupuncture for Insomnia Disorder and Oxidative Stress: A Randomized, Double-Blind, Sham-Controlled Trial

Author

Yeung,Wing-Fai, Yu,Branda Yee-Man, Yuen,John Wai-Man, Ho,Janice Yuen Shan, Chung,Ka-Fai, Zhang,Zhang-Jin, Mak,Deejay Suen Yui, Suen,Lorna Kwai-Ping, Ho,Lai-Ming, Yeung,Wing-Fai, Yu,Branda Yee-Man, Yuen,John Wai-Man, Ho,Janice Yuen Shan, Chung,Ka-Fai, Zhang,Zhang-Jin, Mak,Deejay Suen Yui, Suen,Lorna Kwai-Ping, and Ho,Lai-Ming

Abstract

Wing-Fai Yeung,1 Branda Yee-Man Yu,2 John Wai-Man Yuen,1 Janice Yuen Shan Ho,1 Ka-Fai Chung,3 Zhang-Jin Zhang,4 Deejay Suen Yui Mak,5 Lorna Kwai-Ping Suen,6 Lai-Ming Ho7 1School of Nursing, The Hong Kong Polytechnic University, The Hong Kong SAR, People’s Republic of China; 2Department of Psychology, The University of Hong Kong, The Hong Kong SAR, People’s Republic of China; 3Department of Psychiatry, The University of Hong Kong, The Hong Kong SAR, People’s Republic of China; 4School of Chinese Medicine, The University of Hong Kong, The Hong Kong SAR, People’s Republic of China; 5School of Medical and Health Sciences, Tung Wah College, The Hong Kong SAR, People’s Republic of China; 6School of Nursing, Tung Wah College, The Hong Kong SAR, People’s Republic of China; 7School of Public Health, The University of Hong Kong, The Hong Kong SAR, People’s Republic of ChinaCorrespondence: Wing-Fai YeungSchool of Nursing, The Hong Kong Polytechnic University, Room FG429, Hung Hom, Hong Kong, People’s Republic of ChinaEmail jerry-wf.yeung@polyu.edu.hkBackground: Acupuncture is an alternative treatment for improving sleep, and it may attenuate oxidative stress, which is a possible pathophysiological factor in insomnia. The aim of this study was to examine the efficacy and safety of a semi-individualized acupuncture in improving sleep and explore its effect on oxidative stress parameters in adults with insomnia disorder.Methods: In this randomized sham-controlled trial, 140 participants were randomly assigned to either a 4-week semi-individualized traditional acupuncture (TA) or noninvasive sham acupuncture (SA). The primary outcome measure was the sleep-diary-derived sleep efficiency. Other outcomes included sleep diary and actigraphy, Insomnia Severity Index, anxiety and depressive symptoms, and quality of life. Blood samples were taken to measure oxidative stress parameters (malondialdehyde, glutathione peroxidase, paraoxonase, and arylesterase).Results: Althou

Published
2021

33. Additional file 2 of Pediatric tuina for the treatment of attention deficit hyperactivity disorder (ADHD) symptoms in preschool children: study protocol for a pilot randomized controlled trial

Author

Shu-Cheng Chen, Yu, Juan, Suen, Lorna Kwai-Ping, Sun, Yan, Ya-Zheng Pang, Wang, Dong-Dong, Zhao, Wen-Xia, and Wing-Fai Yeung

Subjects
ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION
Abstract

Additional file 2: World Health Organization Trial Registration Data Set.

Published
2020
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38. Predictive value of serological indices for guiding bundle of care to prevent the occurrence of poststroke fatigue for ischemic stroke survivors

Author

Ma, Qiuping, Yang, Jinpan, Suen, Lorna Kwai Ping, Zhang, Jialin, Yang, Chunxiao, and Zhong, Mingyang

Abstract

Almost half of ischemic stroke (IS) survivors have poststroke fatigue (PSF) during rehabilitation, which can reduce their rehabilitation compliance and quality of life. The primary link of PSF management is early identification, which can guide bundle of care for prevention. This study aimed to explore the predictive value of serological indicators for guiding bundle of care to prevent the occurrence of PSF among IS survivors. This study was a prospective observational study. A total of 350 patients with IS who were hospitalized in 2 tertiary hospitals in Nanning from October 2022 to September 2023 were selected. The general data of patients and serological indicators within 24 hours of admission were collected. Based on the follow-up results, the patients were divided into the PSF group and the NPSF group. Multivariate logistic regression analysis was used to screen the risk factors affecting the occurrence of PSF, and the receiver operating characteristic curve (ROC curve) method was used to analyze the predictive value of this factor. The incidence of acute-phase PSF among elderly patients with IS was 49.26%. The elevated levels of fasting plasma glucose (FPG) (OR = 1.485, 95% CI: 1.145–1.925, P = .003), total cholesterol (TC) (OR = 1.394, 95% CI: 1.013–1.917, P = .041), C-reactive protein (CRP) (OR = 1.394, 95% CI: 1.013–1.917, P = .041), and homocysteine (Hcy) (OR = 1.370, 95% CI: 1.233–1.524, P < .001) were risk factors of PSF in elderly patients with acute IS (P < .05). FPG (area under the curve = 0.632), TC (area under the curve = 0.621), CRP (area under the curve = 0.889), and Hcy (area under the curve = 0.807) had a good predictive value for acute-phase PSF, and the combination of the 4 indicators could further improve the predictive efficacy (area under the curve = 0.938, sensitivity 86.2%, specificity 90.7%, P < .05). The elevated levels of FPG, TC, CRP, and Hcy could predict the risk of PSF, and the combination of the 4 indicators can effectively improve prediction efficiency and provide a reference for guiding the formulation of bundle nursing programs.

Published
2024
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39. Network analysis of depressive symptoms in Hong Kong residents during the COVID-19 pandemic.

Author

Cheung, Teris, Jin, Yu, Lam, Simon, Su, Zhaohui, Hall, Brian J., Xiang, Yu-Tao, the International Research Collaboration on COVID-19, Suen, Lorna Kwai Ping, Chan, Shun, HO, Hilda Sze Wing, Lam, Kin Bong Hubert, Huang, Emma Yun-zhi, Xiao, Ying, Pereira-Ávila, Fernanda Maria Vieira, Gir, Elucir, Yildirim, Menevse, Intepeler, Seyda Seren, Lantta, Tella, Lee, Kyungmi, and Shin, Nayeon

Published
2021
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45. Efficacy of Auricular Therapy for Pain Management: A Systematic Review and Meta-Analysis

Author

Yeh, Chao Hsing, Chiang, Yi Chien, Hoffman, Samuel L., Liang, Zhan, Klem, Mary Lou, Tam, Wilson W. S., Chien, Lung-Chang, and Suen, Lorna Kwai-Ping

Subjects
Article Subject
Abstract

Objective. The objective of this systematic review and meta-analysis was to assess the efficacy of auricular therapy by including a sham therapy control group. Methods. Relevant, randomized clinical trials (RCTs) were identified by searching medical related databases from, depending on journal, 1900 (at the earliest) to 1994 (at the latest) through May 2013. The outcome measure was a pain intensity score. Results. Twenty-two RCTs were identified and 13 RCTs were included for meta-analysis. In these studies, auricular therapy provided significant pain relief when compared to a sham or control group. The overall standardized mean differences (SMD) was 1.59 (95% CI [−2.36, −0.82]) (13 trials, total subject numbers = 806), indicating that, on average, the mean decrease in pain score for auricular therapy group was 1.59 standard deviations greater than the mean decrease for the sham control. In terms of the efficacy of the different treatment methods, auricular acupressure boasts the largest strength of evidence for pain relief, followed by auricular acupuncture. Electroacupuncture stimulation did not show significant evidence for efficacy, which may be due to the small sample size (i.e., only 19 subjects were included). Conclusion. Further large-scale RCTs are needed to determine the efficacy of auricular therapy for pain.

Published
2014
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50. Auricular Point Acupressure to Manage Chronic Low Back Pain in Older Adults: A Randomized Controlled Pilot Study

Author

Yeh, Chao Hsing, primary, Morone, Natalia E., additional, Chien, Lung-Chang, additional, Cao, Yuling, additional, Lu, Huijuan, additional, Shen, Juan, additional, Margolis, Leah, additional, Bhatnagar, Shreya, additional, Hoffman, Samuel, additional, Liang, Zhan, additional, Glick, Ronald M., additional, and Suen, Lorna Kwai-Ping, additional

Published
2014
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