107 results on '"Sparrow JM"'
Search Results
2. Factors related to the final visual outcome of 425 patients with traumatic hyphaema
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Sparrow Jm, Ng Cs, A R Rosenthal, and Strong Np
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medicine.medical_specialty ,Pediatrics ,Multivariate analysis ,genetic structures ,Eye disease ,Population ,Visual Acuity ,Poison control ,Wounds, Nonpenetrating ,Retina ,Eye Injuries ,Blunt ,Risk Factors ,medicine ,Humans ,education ,Hyphema ,Retrospective Studies ,education.field_of_study ,business.industry ,Retrospective cohort study ,medicine.disease ,eye diseases ,Surgery ,Ophthalmology ,sense organs ,Complication ,business - Abstract
A retrospective study of the visual outcome of 425 in-patients with traumatic hyphaema has been conducted. A multivariate analysis demonstrated that after adjusting for age, sex and pre-existing poor vision, the size of hyphaema on presentation and the presence of retinal damage were significant predictors of a worse final visual outcome (p = 0.00003 and 0.00001 respectively). Topical steroid and/or cycloplegic medication, and the occurrence of secondary haemorrhage did not influence the final visual outcome after adjustment for the other variables. These data illustrate, in an unselected sequential population of patients, the role of these factors in terms of final visual outcome following hyphaema from blunt ocular trauma.
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- 1992
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3. The Cataract National Dataset electronic multi-centre audit of 55,567 operations: risk indicators for monocular visual acuity outcomes.
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Sparrow JM, Taylor H, Qureshi K, Smith R, Birnie K, Johnston RL, Sparrow, J M, Taylor, H, Qureshi, K, Smith, R, Birnie, K, Johnston, R L, and UK EPR user group
- Abstract
Aims: To report risk factors for visual acuity (VA) improvement and harm following cataract surgery using electronically collected multi-centre data conforming to the Cataract National Dataset (CND).Methods: Routinely collected anonymised data were remotely extracted from the electronic patient record systems of 12 participating NHS Trusts undertaking cataract surgery. Following data checks and cleaning, analyses were performed to identify risk indicators for: (1) a good acuity outcome (VA 6/12 or better), (2) the pre- to postoperative change in VA, and (3) VA loss (doubling or worse of the visual angle).Results: In all, 406 surgeons from 12 NHS Trusts submitted data on 55,567 cataract operations. Preoperative VA was known for 55,528 (99.9%) and postoperative VA outcome for 40,758 (73.3%) operations. Important adverse preoperative risk indicators found in at least 2 of the 3 analyses included older age (3), short axial length (3), any ocular comorbidity (3), age-related macular degeneration (2), diabetic retinopathy (3), amblyopia (2), corneal pathology (2), previous vitrectomy (2), and posterior capsule rupture (PCR) during surgery (3). PCR was the only potentially modifiable adverse risk indicator and was powerfully associated with VA loss (OR=5.74).Conclusion: Routinely collected electronic data conforming to the CND provide sufficient detail for identification and quantification of preoperative risk indicators for VA outcomes of cataract surgery. The majority of risk indicators are intrinsic to the patient or their eye, with a notable exception being PCR during surgery. [ABSTRACT FROM AUTHOR]- Published
- 2012
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4. The Cataract National Dataset electronic multi-centre audit of 55,567 operations: variation in posterior capsule rupture rates between surgeons.
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Johnston RL, Taylor H, Smith R, Sparrow JM, Johnston, R L, Taylor, H, Smith, R, and Sparrow, J M
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Aims: To demonstrate variations in posterior capsule rupture (PCR) rate between surgeons of the same and different grades as a by-product of routine clinical care.Method: NHS departments using electronic medical record (EMR) systems to collect the Cataract National Dataset (CND) were invited to submit data. Data were remotely extracted, anonymised, assessed for conformity and completeness, and analysed for rates of PCR for individual surgeons within each of the three grades.Results: Data were extracted on 55,567 cataract operations performed at 12 NHS trusts by 406 surgeons between November 2001 and July 2006. Data on the grade of 404 of the 406 surgeons who contributed to the study were available for 55,515 cases (99.9%) and were used for this analysis. Variation in PCR rate between surgeons was highest for the most junior grade of surgeon and between those surgeons contributing relatively few cases to the data set. Variation in PCR was lowest among experienced surgeons contributing large numbers of cases to the data set.Conclusions: Considerable variation in PCR rate exists both between and within surgical grades. Routine electronic collection of the CND allows detailed analysis of variations in PCR rates between individual surgeons. To define acceptable limits for this benchmark complication of cataract surgery, further work is needed to adjust surgeons' outcomes for the case mix complexity. [ABSTRACT FROM AUTHOR]- Published
- 2010
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5. The Cataract National Dataset electronic multicentre audit of 55,567 operations: when should IOLMaster biometric measurements be rechecked?
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Knox Cartwright NE, Johnston RL, Jaycock PD, Tole DM, Sparrow JM, Knox Cartwright, N E, Johnston, R L, Jaycock, P D, Tole, D M, and Sparrow, J M
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Purpose: Calculation of intraocular lens (IOL) power for implantation during cataract surgery depends on ocular biometric measurements. The aim of this study was to characterise the normal range of intra- and interindividual variation in axial length (AL) and corneal power (K) when IOLMaster measurements were possible and to derive recommendations as to which outlying measurements merit verification before acceptance.Methods: The Medisoft electronic patient database contains prospectively collected data conforming to the United Kingdom (UK) Cataract National Dataset on 55,567 cataract operations. From this AL and K information on the 32,556 eyes (14,016 paired) of patients older than 25 years, without corneal pathology, history of intraocular surgery and who had all biometric measurements taken with the Zeiss IOLMaster (Carl Zeiss Meditec) were extracted. R 2.8.1 (R Foundation for Statistical Computing) was used for statistical analysis.Results: Mean age was 76.4 years and 62.0% were female. Mean (95% confidence interval) values for AL, mean K and corneal astigmatism were 23.40 (21.27-26.59) mm, 43.90 (40.94-47.01) D and 1.04 (<2.50) D. Nearly all astigmatism was either with or against the rule. Differences between paired eyes were not statistically significant. 95% individuals had asymmetry of AL and mean K<0.70 mm and 0.92 D, respectively.Conclusions: On the basis of approximation of the 95% CI above, it is suggested that AL, mean K and keratometric astigmatism measurements outside the ranges 21.30-26.60 mm, 41.00-47.00 D and >2.50 D, respectively, and intraindividual asymmetry of AL >0.70 mm or mean K>0.90 D should be verified before acceptance. [ABSTRACT FROM AUTHOR]- Published
- 2010
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6. Ocular air gun injuries: a one-year surveillance study in the UK and Eire (BOSU). 2001-2002.
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Shuttleworth GN, Galloway P, Sparrow JM, Lane C, Shuttleworth, G N, Galloway, P, Sparrow, J M, and Lane, C
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Aims: The vulnerability of the eye means that ocular air gun injuries figure prominently in the medical literature. This Study reports the results of the first ocular air gun injury surveillance study.Methods: Ocular air gun injuries were reported to the British Ophthalmic Surveillance Unit (BOSU; United Kingdom and Eire) for the period November 2001-December 2002 (13 months). Two questionnaires were used to collect demographic details, circumstances of injury, details of injuries, medical management and outcome.Results: A total of 105 initial and 99 follow-up questionnaires were returned. Eighty-six ocular air gun injuries occurred during the last 12 months of surveillance yielding a corrected, estimated incidence of 91-115 injuries/year. Injuries were most frequent in August/September, and 90% (95/105) of victims were men with mean age of 17.5 years (74% under 18 years). In all, 40% (32/81) of injuries occurred at home and 53% (43/81) in a public place. 23% (19/84) of injuries were deliberate, 66% (69/104) of injuries were severe and 20% (21/105) resulted in ruptured globes. In all, 54% (48/89) required hospital admission and 41 required surgery. A total of 11% (12/105) of eyes were either enucleated or eviscerated. Final visual acuity was6/12 (Snellen) in 65% (59/91). Moderate/significant cosmetic deformities were recorded in 10% (8/77) and restricted ocular movements in 5% (4/72). Conclusions: Ocular air gun injuries damage sight and leave lasting morbidity. The demographics and circumstances of injury are well documented with access to, and unsupervised use of, air guns, appearing the principal risks for injury. [ABSTRACT FROM AUTHOR]- Published
- 2009
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7. The Cataract National Dataset electronic multicentre audit of 55,567 operations: antiplatelet and anticoagulant medications.
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Benzimra JD, Johnston RL, Jaycock P, Galloway PH, Lambert G, Chung AK, Eke T, Sparrow JM, and EPR User Group
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- 2009
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8. The Cataract National Dataset Electronic Multi-centre Audit of 55,567 operations: anaesthetic techniques and complications.
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El-Hindy N, Johnston RL, Jaycock P, Eke T, Braga AJ, Tole DM, Galloway P, Sparrow JM, UK EPR user group, El-Hindy, N, Johnston, R L, Jaycock, P, Eke, T, Braga, A J, Tole, D M, Galloway, P, and Sparrow, J M
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Purpose: The primary aim of this study was to detail anaesthetic techniques and complications for cataract surgery in the UK.Methods: The Cataract National Dataset was extracted from 12 National Health Service Trusts that used the same electronic patient record system between November 2001 and July 2006 on a total of 55,567 cataract operations.Results: Anaesthesia was administered by an ophthalmologist in 56.7% of the cases, a career anaesthetist in 42.1% of the cases, a clinical assistant anaesthetist in 0.3% of the cases, and staff were not recorded in 0.9% of the cases. Local anaesthesia (LA) was used in 95.5%, with topical anaesthesia alone in 22.3% (range by site, 0-99.8%), topical and intracameral in 4.7% (range, 0-24.1%), subtenons in 46.9% (range, 0-81.8%), peribulbar in 19.5% (range, 0-63.4%), and retrobulbar in 0.5% (range, 0-5.3%). One or more minor complications occurred in 4.3% of 38,058 local blocks administered by either sharp needle or subtenons (blunt) cannula. Minor complications were 2.3 times more common with subtenons blocks (P<0.001). Serious complications, defined as sight or life threatening occurred in 25 eyes, 0.066%, undergoing sharp needle or subtenons cannula blocks. Sharp needle techniques had a 2.5-fold increased risk of serious complications compared with subtenons cannula techniques (P=0.026).Conclusion: Subtenons anaesthesia was the most widely used anaesthetic technique for cataract surgery but wide variation existed by site. There was a low rate of reported LA complications. There was a statistically significant increased risk of serious complications with sharp needle anaesthesia compared with subtenons technique. [ABSTRACT FROM AUTHOR]- Published
- 2009
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9. The Cataract National Dataset electronic multicentre audit of 55,567 operations: risk stratification for posterior capsule rupture and vitreous loss.
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Narendran N, Jaycock P, Johnston RL, Taylor H, Adams M, Tole DM, Asaria RH, Galloway P, and Sparrow JM
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- 2009
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10. The Cataract National Dataset electronic multi-centre audit of 55,567 operations: updating benchmark standards of care in the United Kingdom and internationally.
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Jaycock P, Johnston RL, Taylor H, Adams M, Tole DM, Galloway P, Canning C, Sparrow JM, UK EPR user group, Jaycock, P, Johnston, R L, Taylor, H, Adams, M, Tole, D M, Galloway, P, Canning, C, and Sparrow, J M
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Aims: To pilot the use of the Cataract National Dataset (CND) using multi-centre data from Electronic Patient Record (EPR) systems and to demonstrate the ability of the CND to deliver certain of its intended benefits, including detailed preoperative profiling of cataract surgery patients and updating of benchmark standards of care in the NHS and beyond.Methods: NHS departments using EPR systems to collect a minimum preoperative, anaesthetic, operative and postoperative data set, the CND, were invited to submit data, which were remotely extracted, anonymised, assessed for conformity and completeness, and analysed.Results: Four-hundred and six surgeons from 12 NHS Trusts submitted data on 55,567 cataract operations between November 2001 and July 2006 (86% from January 2004). Mean age (SD) was 75.4 (10.4) years, 62.0% female. Surgery was for first eyes in 58.5%, under local anaesthesia in 95.5% and by phacoemulsification in 99.7%. Trainees performed 33.9% of operations. Preoperative visual acuity (VA) was 6/12 or better in 42.9% eyes overall, in 35.3% first eyes and in 55.3% second eyes. Complication rates included the following: posterior capsule rupture and/or vitreous loss of 1.92%, simple zonule dialysis of 0.46% and retained lens fragments of 0.18%. Postoperative VA of 6/12 or better (and 6/6 or better) was achieved for 91.0% (45.9%) of all eyes, 94.7% (51.0%) of eyes with no co-pathologies and 79.9% (30.2%) of eyes with one or more co-pathologies respectively.Conclusions: The CND is fit for purpose, is able to deliver useful benefits and can be collected as part of routine clinical care via EPR systems. This survey confirms shifts in practice since the 1997-1998 UK National Survey with full conversion to phacoemulsification, better preoperative acuity, a halving of the surgical 'index' benchmark complication of posterior capsule rupture and/or vitreous loss, and improved VA outcomes. [ABSTRACT FROM AUTHOR]- Published
- 2009
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11. The Royal College of Ophthalmologists' National Ophthalmology Database study of cataract surgery: Report 9, Risk factors for posterior capsule opacification.
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Donachie PHJ, Barnes BL, Olaitan M, Sparrow JM, and Buchan JC
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- Humans, Female, Lens Implantation, Intraocular adverse effects, Retrospective Studies, Risk Factors, Postoperative Complications etiology, Capsule Opacification epidemiology, Capsule Opacification etiology, Capsule Opacification surgery, Lenses, Intraocular adverse effects, Ophthalmology, Ophthalmologists, Lens Capsule, Crystalline surgery, Cataract etiology
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Background/objectives: Posterior Capsule Opacification (PCO) is the most common long-term post-operative adverse occurrence after cataract surgery often requiring treatment with YAG laser posterior capsulotomy. This study aimed to identify potential risk factors, known at the time of cataract surgery, that influence the development of PCO., Subject/methods: A retrospective study of publicly funded cataract surgery from The Royal College of Ophthalmologists' National Ophthalmology Database. Eligible for analysis were 500,872 cataract operations performed in 41 participating centres., Results: The 500,872 operations were performed on 243,167 (48.5%) left eyes and 257,705 (51.5%) right eyes from 373,579 patients by 2196 surgeons. Post-cataract PCO was recorded for 61,778 (12.3%) eyes and the six month, one, three, five and nine year observed rates of PCO were 2.3%, 4.4%, 19.7%, 34.0% and 46.9% respectively. Different PCO profiles were observed between IOL materials and the identified risk factors that increased the risk of developing PCO included hydrophilic IOL material, axial length >26 mm, the presence of high myopia and implantation of lower IOL powers and previous vitrectomy surgery, along with younger age and female gender., Conclusions: Many factors influence the development of PCO relating to the patient, the eye, the lens and the surgery. Some factors are modifiable such as IOL material, therefore the opportunity exists to attempt to reduce PCO rates, benefitting patients and the UK NHS., (© 2022. The Author(s), under exclusive licence to The Royal College of Ophthalmologists.)
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- 2023
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12. The influence of weather on the population dynamics of common mosquito vector species in the Canadian Prairies.
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Baril C, Pilling BG, Mikkelsen MJ, Sparrow JM, Duncan CAM, Koloski CW, LaZerte SE, and Cassone BJ
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- Animals, Mosquito Vectors, Grassland, Canada epidemiology, Weather, Population Dynamics, Culicidae, Culex, Aedes
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Background: Mosquito seasonal activity is largely driven by weather conditions, most notably temperature, precipitation, and relative humidity. The extent by which these weather variables influence activity is intertwined with the animal's biology and may differ by species. For mosquito vectors, changes in weather can also alter host-pathogen interactions thereby increasing or decreasing the burden of disease., Methods: In this study, we performed weekly mosquito surveillance throughout the active season over a 2-year period in Manitoba, Canada. We then used Generalized Linear Mixed Models (GLMMs) to explore the relationships between weather variables over the preceding 2 weeks and mosquito trap counts for four of the most prevalent vector species in this region: Oc. dorsalis, Ae. vexans, Cx. tarsalis, and Cq. perturbans., Results: More than 265,000 mosquitoes were collected from 17 sampling sites throughout Manitoba in 2020 and 2021, with Ae. vexans the most commonly collected species followed by Cx. tarsalis. Aedes vexans favored high humidity, intermediate degree days, and low precipitation. Coquillettidia perturbans and Oc. dorsalis activity increased with high humidity and high rainfall, respectively. Culex tarsalis favored high degree days, with the relationship between number of mosquitoes captured and precipitation showing contrasting patterns between years. Minimum trapping temperature only impacted Ae. vexans and Cq. perturbans trap counts., Conclusions: The activity of all four mosquito vectors was affected by weather conditions recorded in the 2 weeks prior to trapping, with each species favoring different conditions. Although some research has been done to explore the relationships between temperature/precipitation and Cx. tarsalis in the Canadian Prairies, to our knowledge this is the first study to investigate other commonly found vector species in this region. Overall, this study highlights how varying weather conditions can impact mosquito activity and in turn species-specific vector potential., (© 2023. The Author(s).)
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- 2023
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13. Royal College of Ophthalmologists' National Ophthalmology Database study of cataract surgery: report 8, cohort analysis of the relationship between intraoperative complications of cataract surgery and axial length.
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Day AC, Norridge CFE, Donachie PHJ, Barnes B, and Sparrow JM
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- Cohort Studies, Humans, Intraoperative Complications epidemiology, Intraoperative Complications etiology, Retrospective Studies, State Medicine, Visual Acuity, Cataract epidemiology, Cataract Extraction adverse effects, Ophthalmologists, Ophthalmology, Phacoemulsification
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Objectives: To describe the relationships between axial length and intraoperative complications in patients undergoing cataract surgery., Design: Cohort analysis of the Royal College of Ophthalmologists' National Ophthalmology Database (RCOphth NOD)., Setting: 110 National Health Service Trusts in England, Health Boards in Wales, Independent Sector Treatment Centres and Guernsey., Participants: 820 354 patients, aged 18 years or older, undergoing cataract surgery. Eligible operations were those from centres with at least 50 operations with a recorded axial length measurement and age at surgery between 1 April 2010 and 31 August 2019., Interventions: Phacoemulsification where the primary intention was cataract surgery alone., Outcome Measures: Posterior capsule rupture (PCR) and other recorded intraoperative complications., Results: 1 211 520 eligible operations were performed by 3210 surgeons. The baseline axial length was <21 mm (short eyes) for 17 170 (1.4%) eyes, 21-28 mm (medium eyes) for 1 182 513 (97.6%) eyes and >28 mm (long eyes) for 11 837 (1.0%) eyes. The median age at surgery was younger for patients with long eyes than those with short or medium eyes. The rate of any intraoperative complication was higher for short eyes than medium or long with complication rates of 4.5%, 2.9% and 3.3%, respectively (p<0.001). PCR occurred in 1.40% surgeries overall, and in 1.53%, 1.40% and 1.61% of short, medium and long eyes, respectively (p=0.043, not significant at the 1% level)., Conclusions: Overall PCR rates for cataract surgery in RCOphth NOD contributing centres are lower than previously reported and there is little change in PCR rates by axial length. Short eyes were more likely to have an intraoperative complication than medium or long eyes., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
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- 2022
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14. Primary trabeculectomy versus primary glaucoma eye drops for newly diagnosed advanced glaucoma: TAGS RCT.
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King AJ, Fernie G, Hudson J, Kernohan A, Azuara-Blanco A, Burr J, Homer T, Shabaninejad H, Sparrow JM, Garway-Heath D, Barton K, Norrie J, McDonald A, Vale L, and MacLennan G
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- Aged, Cost-Benefit Analysis, Female, Humans, Male, Middle Aged, Ophthalmic Solutions, Quality of Life, Quality-Adjusted Life Years, Glaucoma, Glaucoma, Open-Angle drug therapy, Glaucoma, Open-Angle surgery, Trabeculectomy
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Background: Patients diagnosed with advanced primary open-angle glaucoma are at a high risk of lifetime blindness. Uncertainty exists about whether primary medical management (glaucoma eye drops) or primary surgical treatment (augmented trabeculectomy) provide the best and safest patient outcomes., Objectives: To compare primary medical management with primary surgical treatment (augmented trabeculectomy) in patients with primary open-angle glaucoma presenting with advanced disease in terms of health-related quality of life, clinical effectiveness, safety and cost-effectiveness., Design: This was a two-arm, parallel, multicentre, pragmatic randomised controlled trial., Setting: Secondary care eye services., Participants: Adult patients presenting with advanced primary open-angle glaucoma in at least one eye, as defined by the Hodapp-Parrish-Anderson classification of severe glaucoma., Intervention: Primary medical treatment - escalating medical management with glaucoma eye drops. Primary trabeculectomy treatment - trabeculectomy augmented with mitomycin C., Main Outcome Measures: The primary outcome was health-related quality of life measured with the Visual Function Questionnaire-25 at 2 years post randomisation. Secondary outcomes were mean intraocular pressure; EQ-5D-5L; Health Utilities Index 3; Glaucoma Utility Index; cost and cost-effectiveness; generic, vision-specific and disease-specific health-related quality of life; clinical effectiveness; and safety., Results: A total of 453 participants were recruited. The mean age of the participants was 67 years (standard deviation 12 years) in the trabeculectomy arm and 68 years (standard deviation 12 years) in the medical management arm. Over 65% of participants were male and more than 80% were white. At 24 months, the mean difference in Visual Function Questionnaire-25 score was 1.06 (95% confidence interval -1.32 to 3.43; p = 0.383). There was no evidence of a difference between arms in the EQ-5D-5L score, the Health Utilities Index or the Glaucoma Utility Index. At 24 months, the mean intraocular pressure was 12.40 mmHg in the trabeculectomy arm and 15.07 mmHg in the medical management arm (mean difference -2.75 mmHg, 95% confidence interval -3.84 to -1.66 mmHg; p < 0.001). Fewer types of glaucoma eye drops were required in the trabeculectomy arm. LogMAR visual acuity was slightly better in the medical management arm (mean difference 0.07, 95% confidence interval 0.02 to 0.11; p = 0.006) than in the trabeculectomy arm. There was no evidence of difference in safety between the two arms. A discrete choice experiment updated the utility values for the Glaucoma Utility Index. The within-trial economic analysis found a small increase in the mean EQ-5D-5L score (0.04) and that trabeculectomy has a higher probability of being cost-effective than medical management. The incremental cost of trabeculectomy per quality-adjusted life-year was £45,456. Therefore, at 2 years, surgery is unlikely to be considered cost-effective at a threshold of £20,000 per quality-adjusted life-year. When extrapolated over a patient's lifetime in a model-based analysis, trabeculectomy, compared with medical treatment, was associated with higher costs (average £2687), a larger number of quality-adjusted life-years (average 0.28) and higher incremental cost per quality-adjusted life-year gained (average £9679). The likelihood of trabeculectomy being cost-effective at a willingness-to-pay threshold of £20,000 per quality-adjusted life year gained was 73%., Conclusions: Our results suggested that there was no difference between treatment arms in health-related quality of life, as measured with the Visual Function Questionnaire-25 at 24 months. Intraocular pressure was better controlled in the trabeculectomy arm, and this may reduce visual field progression. Modelling over the patient's lifetime suggests that trabeculectomy may be cost-effective over the range of values of society's willingness to pay for a quality-adjusted life-year., Future Work: Further follow-up of participants will allow us to estimate the long-term differences of disease progression, patient experience and cost-effectiveness., Trial Registration: Current Controlled Trials ISRCTN56878850., Funding: This project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment ; Vol. 25, No. 72. See the NIHR Journals Library website for further project information.
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- 2021
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15. Factors affecting visual recovery after successful repair of macula-off retinal detachments: findings from a large prospective UK cohort study.
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Yorston D, Donachie PHJ, Laidlaw DA, Steel DH, Sparrow JM, Aylward GW, and Williamson TH
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- Cohort Studies, Humans, Male, Middle Aged, Prospective Studies, Retrospective Studies, Scleral Buckling, Time Factors, Treatment Outcome, United Kingdom epidemiology, Vitrectomy, Retinal Detachment surgery
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Objective: To identify risk factors affecting visual outcomes in successfully re-attached macula-off rhegmatogenous retinal detachment (RD) surgery., Design: A prospective study, using online databases, of visual outcomes for 2074 macula-off retinal detachments that were successfully re-attached by vitrectomy and internal tamponade. The database included detailed retinal diagrams of each detachment., Main Outcome Measure: The probability of achieving a post-operative visual acuity (VA) of ≤0.30 LogMAR (Snellen 6/12 or better)., Results: Male patients accounted for 64.9% of the sample and the median age was 63 years old. The median pre-operative VA was counting fingers (LogMAR 1.98); this improved to 0.41 LogMAR post-operatively. A post-operative VA of ≤0.30 LogMAR was achieved for 1012 (48.8%) eyes and the factors affecting this were the patient age and gender, pre-operative VA, duration of central vision loss, PVR grade, lens status, total RD and the presence of any ocular co-pathology where the model area under the receiver operator curve was 71.6%., Conclusions: From the identified risk factors that decrease the probability of achieving a post-operative visual acuity of ≤0.30 LogMAR, the most important modifiable risk factor was the duration of central vision loss. Recent macula-off retinal detachments should be repaired within 72 h of the loss of central vision.
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- 2021
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16. The Royal College of Ophthalmologists' National Ophthalmology Database study of cataract surgery: Report 7, immediate sequential bilateral cataract surgery in the UK: Current practice and patient selection.
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Buchan JC, Donachie PHJ, Cassels-Brown A, Liu C, Pyott A, Yip JLY, Zarei-Ghanavati M, and Sparrow JM
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- Aged, Humans, Patient Selection, United Kingdom epidemiology, Visual Acuity, Cataract, Cataract Extraction, Ophthalmologists, Ophthalmology
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Background: Cataract extraction is the most frequently performed surgical intervention in the world and demand is rising due to an ageing demography. One option to address this challenge is to offer selected patients immediate sequential bilateral cataract surgery (ISBCS). This study aims to investigate patient and operative characteristics for ISBCS and delayed bilateral cataract surgery (DSCS) in the UK., Methods: Data were analysed from the Royal College of Ophthalmologists' National Ophthalmology Database Audit (NOD) of cataract surgery. Eligible patients were those undergoing bilateral cataract extraction from centres with a record of at least one ISBCS operation between 01/04/2010 and 31/08/2018. Variable frequency comparison was undertaken with chi-square tests., Results: During the study period, 1073 patients had ISBCS and 248,341 DSCS from 73 centres. A higher proportion of ISBCS patients were unable to lie flat (11.3% vs. 1.8%; p < 0.001), unable to cooperate (9.7% vs. 2.7%; p < 0.001); underwent general anaesthesia (58.7% vs. 6.6% (p < 0.001)); had brunescent/white/mature cataracts (odds ratio (OR) 5.118); no fundal view/vitreous opacities (OR 8.381); had worse pre-operative acuity 0.60 LogMAR ISBCS vs. 0.50 (first) and 0.40 (second eye) DSCS and were younger (mean ages, 71.5 vs. 75.6 years; p < 0.001). Posterior capsular rupture (PCR) rates adjusted for case complexity were comparable (0.98% ISBCS and 0.78% DSCS)., Conclusions: ISBCS was performed on younger patients, with difficulty cooperating and lying flat, worse pre-operative vision, higher rates of known PCR risk factors and more frequent use of general anaesthesia than DSCS in centres recorded on NOD.
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- 2020
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17. The Royal College of Ophthalmologists' National Ophthalmology Database study of cataract surgery: report 4, equity of access to cataract surgery.
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Johnston RL, Day AC, Donachie PHJ, and Sparrow JM
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- England, Health Services Accessibility, Humans, Retrospective Studies, State Medicine, Cataract epidemiology, Cataract Extraction, Ophthalmologists, Ophthalmology
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Objective: To determine whether socioeconomic status influenced the presenting visual acuity prior to first eye cataract surgery in the English National Health Service. Retrospective case series from The Royal College of Ophthalmologists' National Ophthalmology Database Audit. In total 154,223 patients undergoing first eye cataract surgery at 68 centres in England performed between 1st September 2015 and 31st August 2017., Main Outcome Measure: Social deprivation status and pre-operative visual acuity (VA) between centres for patients undergoing first eye cataract surgery in England., Results: The median social deprivation varied between centres and ranged from decile 2 (2nd most deprived decile) to decile 9 (2nd least deprived decile). The pre-operative VA was reported for 143,401 (93.0%) eyes. The median pre-operative VA was 0.50 LogMAR (6/19), and 27.7% eyes had a preoperative VA of 0.30 LogMAR units (6/12) or better. The median pre-operative VA for each centre ranged from 0.30 to 0.60 LogMAR (6/12 to 6/24). The median pre-operative VA was mostly stable across deciles of social deprivation (0.60 LogMAR for decile 1 and 0.50 LogMAR for all other deciles), and some evidence was found linking greater deprivation to worse pre-operative VA and to lower levels of access., Conclusions: We found no strong evidence of inequality for gaining access to first eye cataract surgery in this National Ophthalmology Database analysis, however there was a possible trend towards fewer people in the more deprived deciles accessing surgery, and that some of these are presenting with quite marked levels of visual impairment.
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- 2020
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18. Auditing service delivery in glaucoma clinics using visual field records: a feasibility study.
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Kelly SR, Bryan SR, Sparrow JM, and Crabb DP
- Abstract
Objective: This study aimed to demonstrate that large-scale visual field (VF) data can be extracted from electronic medical records (EMRs) and to assess the feasibility of calculating metrics from these data that could be used to audit aspects of service delivery of glaucoma care., Method and Analysis: Humphrey visual field analyser (HFA) data were extracted from Medisoft EMRs from five regionally different clinics in England in November 2015, resulting in 602 439 records from 73 994 people. Target patients were defined as people in glaucoma clinics with measurable and sustained VF loss in at least one eye (HFA mean deviation (MD) outside normal limits ≥2 VFs). Metrics for VF reliability, stage of VF loss at presentation, speed of MD loss, predicted loss of sight years (bilateral VF impairment) and frequency of VFs were calculated., Results: One-third of people (34.8%) in the EMRs had measurable and repeatable VF loss and were subject to analyses (n=25 760 patients). Median (IQR) age and presenting MD in these patients were 71 (61, 78) years and -6 (-10, -4) dB, respectively. In 19 264 patients with >4 years follow-up, median (IQR) MD loss was -0.2 (-0.8, 0.3) dB/year and median (IQR) intervals between VF examinations was 11 (8, 16) months. Metrics predicting loss of sight years and reliability of examinations varied between centres (p<0.001)., Conclusion: This study illustrates the feasibility of assessing aspects of health service delivery in glaucoma clinics through analysis of VF databases. Proposed metrics could be useful for blindness prevention from glaucoma in secondary care centres., Competing Interests: Competing interests: DPC reports speaker fees from Allergan, Bayer, Santen; unrestricted funding from Allergan, Roche, Santen; consultancy with Centervue—all outside the remit of the submitted work.
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- 2019
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19. The Royal College of Ophthalmologists' National Ophthalmology Database Study of cataract surgery. Report 5: Clinical outcome and risk factors for posterior capsule rupture and visual acuity loss following cataract surgery in patients aged 90 years and older.
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Theodoropoulou S, Grzeda MT, Donachie PHJ, Johnston RL, Sparrow JM, and Tole DM
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- Aged, 80 and over, Female, Humans, Male, Posterior Capsular Rupture, Ocular etiology, Prognosis, Risk Factors, United Kingdom epidemiology, Cataract Extraction adverse effects, Intraoperative Complications, Ophthalmology statistics & numerical data, Posterior Capsular Rupture, Ocular epidemiology, Risk Assessment methods, Societies, Medical statistics & numerical data, Visual Acuity
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Background: Older age is commonly associated with an increased risk of surgical complications and comparatively poor outcomes., Purpose: To report cataract surgery outcomes and risk indicators for patients aged 90 years and older., Methods: Data collected as part of routine cataract care in 34 centres contributing to the United Kingdom Royal College of Ophthalmologists' National Ophthalmology Database (NOD) were analysed. Very elderly people undergoing cataract surgery were profiled in terms of demographics, pre- and postoperative best-measured visual acuity (VA), ocular co-morbidities, intraoperative posterior capsule rupture (PCR) or vitreous loss or both, and risk indicators for operative PCR and adverse VA outcome., Results: 25,856 cataract operations in 19,166 people of 90 years or older between 2000 and 2014 are reported. Preoperative VA was available for 82.4% eyes, being 0.30 LogMAR or better in 21.5%. Postoperative VA was available for 61.8% eyes, being 0.30 LogMAR or better in 74.4%. For those without ocular co-morbidity, postoperative VA was 0.30 LogMAR or better in 84.7%. Various co-morbidities were present in 49% and contributed to an adverse VA outcome. PCR data were available for all operations and occurred in 2.7%. Significant risk indicators for PCR included pseudoexfoliation/phakodonesis, mature cataract, smaller pupil and worse preoperative VA., Conclusions: Slightly poorer cataract surgery outcome results were noted in patients of 90 years or older, more so in patients with ocular co-morbidity which was highly prevalent. However, surgeons should not be deterred from offering cataract surgery to the very elderly as successful visual rehabilitation remains achievable.
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- 2019
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20. Going paperless: improved cataract surgery outcome data quality in a new fully electronic unit.
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Nghiem AZ, Canning C, Eason J, Sparrow JM, and Flynn TH
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- Aged, Data Accuracy, Female, Follow-Up Studies, Humans, Incidence, Male, Retrospective Studies, United Kingdom epidemiology, Visual Acuity, Cataract Extraction statistics & numerical data, Electronic Health Records organization & administration, Intraoperative Complications epidemiology, Ophthalmology statistics & numerical data, Postoperative Complications epidemiology, Quality Improvement, Registries
- Abstract
Objectives: To report outcome data on the first 5000 consecutive cataract cases at a new paperless eye unit and benchmark against the Royal College of Ophthalmologists' National Ophthalmology Database (RCOphth NOD)., Methods: Using the in-built audit tool of the electronic medical records system, data from all cataract operations performed between 1 April 2014 and 13 January 2017 were compiled., Results: Five thousand and eight cases were recorded of which the overall intra-operative complication rate was 2.4%, the most common being posterior capsular rupture-1.14%. Follow-up data on post-operative complications were recorded in 98.6% of cases. Pre- and post-operative visual acuities was measured in 98.0% of cases. In all, 40.8% of eyes achieved a visual acuity of 6/6 or better and 90.7% achieved 6/12 or better., Conclusions: A data set of >5000 consecutive cataract operations was obtained in this eye department. The recording of pre- and post-operative visual acuity in 98% of cases compare very favourably to the RCOphth NOD Audit Report 2017 where pre- and post-operative visual acuities were recorded in only 57.1% of operations. Despite this difference, the outcome measures from this unit and RCOphth NOD were very similar, validating the results of the RCOphth NOD audit reports. Significantly, when applying the RCOphth NOD audit criteria for measuring post-operative visual acuity, approximately 15% of cases were excluded from the data set, reducing the completeness of the data set. Paperless ophthalmology units are feasible in today's NHS and can produce near complete cataract data sets; this can ultimately lead to more comprehensive and reliable aggregate cataract outcome data.
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- 2019
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21. Cataract surgery patient-reported outcome measures: a head-to-head comparison of the psychometric performance and patient acceptability of the Cat-PROM5 and Catquest-9SF self-report questionnaires.
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Sparrow JM, Grzeda MT, Frost NA, Johnston RL, Liu CSC, Edwards L, Loose A, Elliott D, and Donovan JL
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- Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Reproducibility of Results, United Kingdom, Cataract Extraction, Patient Acceptance of Health Care statistics & numerical data, Patient Reported Outcome Measures, Psychometrics instrumentation, Surveys and Questionnaires standards
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Background Cataract surgery is the most frequently undertaken NHS surgical procedure. Visual acuity (VA) provides a poor indication of visual difficulty in a complex visual world. In the absence of a suitable outcome metric, recent efforts have been directed towards the development of a cataract patient-reported outcome measure (PROM) of sufficient brevity, precision, and responsiveness to be implementable in routine high volume clinical services.Aim To compare and contrast the two most promising candidate PROMs for routine cataract surgery.Method The psychometric performance and patient acceptability of the recently UK developed five-item Cat-PROM5 questionnaire was compared with the English translation of the Swedish nine-item Catquest-9SF using Rasch-based performance metrics and qualitative semistructured interviews.Results Rasch-based performance was assessed in 822 typical NHS cataract surgery patients across four centres in England. Both questionnaires demonstrated good to excellent performance for all metrics assessed, including Person Reliability Indices of 0.90 (Cat-PROM5) and 0.88 (Catquest-9SF), responsiveness to surgery (Cohen's standardized effect size) of 1.45 SD (Cat-PROM5) and 1.47 SD (Catquest-9SF) and they were highly correlated with each other (R=0.85). Qualitative assessments confirmed that both questionnaires were acceptable to patients, including in the presence of ocular comorbidities. Preferences were expressed for the shorter Cat-PROM5, which allowed patients to map their own issues to the questions as opposed to the more restrictive specific scenarios of Catquest-9SF.Conclusion The recently UK developed Cat-PROM5 cataract surgery questionnaire is shorter, with performance and patient acceptability at least as good or better than the previous 'best of class' Catquest-9SF instrument.
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- 2018
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22. Cat-PROM5: a brief psychometrically robust self-report questionnaire instrument for cataract surgery.
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Sparrow JM, Grzeda MT, Frost NA, Johnston RL, Liu CSC, Edwards L, Loose A, and Donovan JL
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- Aged, Aged, 80 and over, Female, Humans, Male, Prospective Studies, Quality of Life, Reproducibility of Results, United Kingdom, Cataract Extraction, Patient Reported Outcome Measures, Psychometrics instrumentation, Surveys and Questionnaires standards
- Abstract
PurposeTo develop a short, psychometrically robust and responsive cataract patient reported outcome measure suitable for use in high-volume surgical environments.MethodsA prospective study in which participants completed development versions of questionnaires exploring the quality of their eyesight using items harvested from two existing United Kingdom developed parent questionnaires. Participants were 822 patients awaiting cataract surgery recruited from 4 cataract surgical centres based in the UK. Exclusion criteria were other visually significant comorbidities and age <50 years. An iterative multi-stage process of evaluation using Rasch and factor analyses with sequential item reduction was undertaken.ResultsA definitive item set of just five items delivered performance in accordance with the requirements of the Rasch model: no threshold disordering, no misfitting items, Rasch-based reliability 0.90, person separation 2.98, Cronbach's α 0.89, good targeting of questions to patients with cataract with pre-operative item mean -0.41 logits and absence of significant floor or ceiling effects, minor deviations of item invariance, and confirmed unidimensionality. The test-re-test repeatability intra-class correlation coefficient was 0.89 with excellent responsiveness to surgery, Cohen's d -1.45 SD. Rasch calibration values are provided for Cat-PROM5 users.ConclusionsA psychometrically robust and highly responsive five-item cataract surgery patient reported outcome measure has been developed, which is suitable for use in high-volume cataract surgical services.
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- 2018
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23. The Royal College of Ophthalmologists' Glaucoma Commissioning Guidance: executive summary.
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Khawaja AP, Sherratt MA, and Sparrow JM
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- Critical Pathways organization & administration, Glaucoma prevention & control, Humans, United Kingdom, Community Health Services organization & administration, Glaucoma therapy, Ophthalmology organization & administration
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- 2017
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24. The Royal College of Ophthalmologists' National Ophthalmology Database Study of cataract surgery: report 2, relationships of axial length with ocular copathology, preoperative visual acuity, and posterior capsule rupture.
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Day AC, Donachie PH, Sparrow JM, and Johnston RL
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- Adolescent, Adult, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Preoperative Period, Prospective Studies, Societies, Medical, United Kingdom, Vitreous Body pathology, Axial Length, Eye pathology, Cataract Extraction statistics & numerical data, Databases, Factual, Eye Diseases epidemiology, Ophthalmology statistics & numerical data, Posterior Capsular Rupture, Ocular epidemiology, Visual Acuity physiology
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Purpose: To describe the relationships of axial length with ocular copathology, preoperative visual acuity, and posterior capsule rupture rates in patients undergoing cataract surgery.DesignThe Royal College of Ophthalmologists' National Ophthalmology Database (NOD) study., Methods: Anonymised data on 180 114 eyes from 127 685 patients undergoing cataract surgery between August 2006 and November 2010 were collected prospectively from 28 sites. Data parameters included: demographics, biometry, ocular copathology, visual acuity measurements, and surgical complications including posterior capsule rupture, or vitreous loss or both (PCR)., Results: Consultant surgeons performed a higher proportion of operations on eyes whose axial length were at the extremes. Glaucoma and age related macular degeneration were more common in eyes with shorter axial lengths, whilst previous vitrectomy was associated with longer axial lengths. Eyes with brunescent or white cataracts or amblyopia were more common at both axial length extremes. Preoperative visual acuities were similar for eyes with axial length measurements up to approximately 28 mm and worse for eyes with longer axial length measurements. PCR rates showed little change with axial length (overall mean 1.95%, 95% CI: 1.89 to 2.01%), except for a borderline increase in eyes with axial length <20.0 mm where rates were 3.6% (95% CI: 2.0 to 6.3%). The likelihood of PCR in eyes with axial length <20.0 mm was 1.88 times higher than those of ≥20.0 mm (P=0.0373)., Conclusion: Rates of ocular comorbidities vary by axial length. PCR rates in eyes with very short or long axial lengths were lower than expected.
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- 2015
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25. The Royal College of Ophthalmologists' National Ophthalmology Database study of cataract surgery: report 1, visual outcomes and complications.
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Day AC, Donachie PH, Sparrow JM, and Johnston RL
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- Aged, Aged, 80 and over, Databases, Factual, Female, Humans, Intraoperative Complications, Male, Middle Aged, Outcome Assessment, Health Care, Posterior Capsular Rupture, Ocular etiology, Postoperative Complications, Prospective Studies, United Kingdom, Visual Acuity, Vitreous Detachment etiology, Cataract Extraction adverse effects, Cataract Extraction statistics & numerical data
- Abstract
Aims: To describe the outcomes of cataract surgery in the United Kingdom., Methods: Anonymised data on 180 114 eyes from 127 685 patients undergoing cataract surgery between August 2006 and November 2010 were collected prospectively from 28 sites. Outcome measures included intraoperative and postoperative complication rates, and preoperative and postoperative visual acuities., Results: Median age at first eye surgery was 77.1 years, 36.9% cases had ocular co-pathology and 41.0% patients underwent cataract surgery on both eyes. Preoperative visual acuity was 0.30 logMAR or better in 32.0% first eyes and 47.7% second eyes. Postoperative best-measured visual acuity was 0.00 and 0.30 logMAR or better in 50.8 and 94.6% eyes without ocular co-pathology, and 32.5 and 79.9% in eyes with co-pathology. For eyes without co-pathology, postoperative uncorrected distance visual acuity was 0.00 and 0.30 logMAR or better in 27.3 and 80.9% eyes. Posterior capsule rupture or vitreous loss or both occurred in 1.95% cases, and was associated with a 42 times higher risk of retinal detachment surgery within 3 months and an eight times higher risk of endophthalmitis., Conclusion: These results provide updated data for the benchmarking of cataract surgery. Visual outcomes, and the rate of posterior capsule rupture or vitreous loss or both appear stable over the past decade.
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- 2015
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26. United Kingdom National Ophthalmology Database Study: Diabetic Retinopathy; Report 1: prevalence of centre-involving diabetic macular oedema and other grades of maculopathy and retinopathy in hospital eye services.
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Keenan TD, Johnston RL, Donachie PH, Sparrow JM, Stratton IM, and Scanlon P
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- Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Databases, Factual, Diabetic Retinopathy classification, Electronic Health Records, Female, Hospital Departments, Humans, Infant, Macular Edema classification, Male, Middle Aged, Prevalence, United Kingdom epidemiology, Young Adult, Diabetic Retinopathy epidemiology, Macular Edema epidemiology, Ophthalmology statistics & numerical data, State Medicine statistics & numerical data
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Aims: To report estimates of the prevalence of diabetic retinopathy (DR) and maculopathy grades for a large cohort of patients managed by the UK hospital eye service (HES)., Methods: Anonymised data were extracted from 30 UK NHS hospital trusts using a single ophthalmic electronic medical record (EMR) for the period from April 2000 to November 2010 to create the National Ophthalmology Database (NOD). From 2007, the EMR facilitated capture of a nationally agreed-upon standardised data set (DR Structured Assessment) relating to the presence or absence of clinical signs of DR and maculopathy. An algorithm in the software automatically calculated the Early Treatment of Diabetic Retinopathy Study grades of retinopathy and maculopathy., Results: Between 2007 and 2010, 307,538 patients had data on the NOD, with 76,127 (24.8%) patients having been recorded as having diabetes. The proportion of patients with diabetes who had a structured assessment increased from 50.7% (2007) to 86.8% (2010). In each NHS year, 12.6-20.6% of eyes with structured assessments had no DR; 59.6-67.3% had non-proliferative DR; and 18.3-20.9% had active or regressed proliferative DR. Clinically significant macular oedema was present in 15.8-18.1% of eyes, and in 8.7-10.0% of eyes, this involved the central macula., Conclusion: This study provides contemporary estimates of the prevalence of retinopathy and maculopathy grades in a large cohort of patients with diabetes managed by the UK HES. Centre-involving diabetic macular oedema, potentially amenable to anti-VEGF therapy, is present in the eyes of almost 10% of these patients. This information is useful for clinicians, health-care economists, and commissioners involved in planning and delivering diabetic eye services.
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- 2013
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27. United Kingdom National Ophthalmology Database Study of Vitreoretinal Surgery: report 1; case mix, complications, and cataract.
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Jackson TL, Donachie PH, Sparrow JM, and Johnston RL
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- Aged, Female, Humans, Incidence, Male, Middle Aged, Postoperative Complications, Prospective Studies, United Kingdom epidemiology, Cataract Extraction statistics & numerical data, Intraoperative Complications epidemiology, Intraoperative Complications etiology, Vitrectomy adverse effects, Vitrectomy methods
- Abstract
Aim: To report the vitreoretinal (VR) surgical case mix in the United Kingdom, the intraoperative complication rate of pars plana vitrectomy (PPV), and the incidence of post-vitrectomy cataract extraction., Methods: Participating hospitals prospectively collected ophthalmic data using a single electronic medical record system, with automatic extraction of anonymised data to a national database. This study included the subset of 11618 VR operations undertaken on 9619 eyes, of 8741 patients, over 8 years, from 27 sites. Surgical data included the indication for surgery, all procedure elements, and whether or not an intraoperative complication occurred. Post-vitrectomy cataract data were also analysed. The main outcome measures were a description of the indications for surgery, intraoperative PPV complication rate, and percentage of eyes undergoing post-vitrectomy cataract surgery (PVCS)., Results: The most common indications for VR intervention were retinal breaks and rhegmatogenous retinal detachment (48.5%), macular hole (9.8%), epiretinal membrane (9.6%), and diabetic eye disease (7.3%). Overall, 7.8% of PPVs had at least one intraoperative complication-the most common were iatrogenic retinal breaks (3.2%), and lens touch (1.2-1.6% of phakic eyes). PVCS occurred in 50.2, 68.7, and 74.0% of eyes at 1, 2, and 3 years, respectively., Conclusion: VR surgery is undertaken for a wide range of conditions, but a small number of diagnoses encompass the majority of cases. Intraoperative PPV complications are not uncommon, and post-vitrectomy cataract is to be expected in most phakic eyes.
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- 2013
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28. The cataract national data set electronic multi-centre audit of 55,567 operations: case-mix adjusted surgeon's outcomes for posterior capsule rupture.
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Sparrow JM, Taylor H, Qureshi K, Smith R, and Johnston RL
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- Cataract Extraction statistics & numerical data, Electronic Health Records statistics & numerical data, England epidemiology, Humans, Medical Audit, Ophthalmology statistics & numerical data, Outcome Assessment, Health Care, Quality of Health Care, Risk Adjustment, Cataract Extraction standards, Clinical Competence standards, Intraoperative Complications epidemiology, Ophthalmology standards, Posterior Capsular Rupture, Ocular epidemiology
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Aims: To develop a methodology for case-mix adjustment of surgical outcomes for individual cataract surgeons using electronically collected multi-centre data conforming to the cataract national data set (CND)., Methods: Routinely collected anonymised data were remotely extracted from electronic patient record (EPR) systems in 12 participating NHS Trusts undertaking cataract surgery. Following data checks and cleaning, analyses were carried out to risk adjust outcomes for posterior capsule rupture rates for individual surgeons, with stratification by surgical grade., Results: A total of 406 surgeons from 12 NHS Trusts submitted data on 55,567 cataract operations between November 2001 and July 2006 (86% from January 2004). In all, 283 surgeons contributed data on >25 cases, providing 54,319 operations suitable for detailed analysis. Case-mix adjusted results of individual surgeons are presented as funnel plots for all surgeons together, and separately for three different grades of surgeon. Plots include 95 and 99.8% confidence limits around the case-mix adjusted outcomes for detection of surgical outliers., Conclusions: Routinely collected electronic data conforming to the CND provides sufficient detail for case-mix adjustment of cataract surgical outcomes. The validation of these risk indicators should be carried out using fresh data to confirm the validity of the risk model. Once validated this model should provide an equitable approach for peer-to-peer comparisons in the context of revalidation.
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- 2011
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29. Response to Bunce et al. Causes of blind and partial sight certifications in England and Wales: April 2007-March 2008.
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Wakefield MJ, Tole DM, Bailey CC, Mundasad MV, and Sparrow JM
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- Blindness etiology, Certification standards, England epidemiology, Humans, Wales epidemiology, Blindness epidemiology, Certification statistics & numerical data, Registries statistics & numerical data
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- 2011
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30. The prevalence and analysis of risk factors for age-related macular degeneration: 18-year follow-up data from the Speedwell eye study, United Kingdom.
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Ngai LY, Stocks N, Sparrow JM, Patel R, Rumley A, Lowe G, Smith GD, and Ben-Shlomo Y
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- Aged, Aged, 80 and over, Cohort Studies, Follow-Up Studies, Humans, Macular Degeneration etiology, Male, Multivariate Analysis, Prevalence, Risk Factors, United Kingdom epidemiology, Macular Degeneration epidemiology
- Abstract
Aims/purpose: To determine the prevalence of age-related maculopathy (ARM) and age-related macular degeneration (AMD) in men aged 65-83 years living in the Speedwell region of Bristol, United Kingdom and identify modifiable risk factors., Methods: A total of 2348 men recruited to the Speedwell prospective cohort study in 1979 were followed up in 1997 with an eye questionnaire and had retinal photographs that were assessed using the International Classification System for ARM., Results: In all, 934 men (66.8% response rate) attended with a mean of 17.9 years (15.3-20.6 years) follow-up. Early ARM (grades 2-3) was found in 9.2% (95% confidence interval (CI) 7.4%, 11.4%) and late age-related maculopathy (grade 4, AMD) in 0.5% (95% CI 0.2%, 1.2%). The risk of ARM (grades 2-4) was increased with raised C-reactive protein and consumption of lard and solid fats, whereas triglyceride levels were associated with a lower risk. The latter were confirmed in multivariable analyses and in addition, haemodynamic measures also predicted risk (eg mean arterial pressure odds ratio (OR) per z-score 1.37, 95% CI 1.04, 1.79)., Conclusions: In a representative cohort of men aged 65-83 from Bristol, United Kingdom, many had macular changes that put them at higher risk of developing AMD. Various modifiable exposures were associated with an increased risk ARM/AMD. Opportunities for screening and undertaking secondary prevention interventions need to be explored to prevent progression of the disease and blindness.
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- 2011
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31. Evaluation of a new cataract surgery referral pathway.
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Park JC, Ross AH, Tole DM, Sparrow JM, Penny J, and Mundasad MV
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- Aged, Aged, 80 and over, Cataract complications, Cataract physiopathology, Critical Pathways organization & administration, Female, Humans, Male, Medical Records standards, Middle Aged, Retrospective Studies, Vision Disorders diagnosis, Vision Disorders etiology, Visual Acuity, Cataract Extraction statistics & numerical data, Family Practice organization & administration, Optometry organization & administration, Referral and Consultation organization & administration
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Aims: To compare the quality of referrals and listing rates of direct optometric referrals vs traditional GP referrals for cataract surgery., Methods: A retrospective cohort of 124 patients referred for cataract surgery was identified (62 via optometric pathway and 62 via GP pathway). The quality of the referral was assessed by establishing if it contained adequate information relating to the College of Optometrists' referral framework document. Age, sex, drug history, listing rate, operative rate, and visual acuity (best corrected) at referral and at the postoperative visit were recorded and compared between the two referral pathways using the Fisher's exact test., Results: Optometric referrals, relative to GP referrals, were more likely to include information relating to objective visual loss (100 vs 87%, P=0.0061) and to counsel the patient (97 vs 18%, P=0.0001). GP referrals, relative to optometric referrals, were more likely to comment on personal circumstances (32 vs 3%, P=0.0001), past medical history (95 vs 68%, P=0.0001), and drug history (94 vs 69%, P=0.0009). Operative rates were higher for the optometric direct referrals relative to GP referrals (87 vs 69%, P=0.0284). There was no difference in the visual acuity before or after surgery between the pathways., Conclusions: Optometric direct cataract referrals provide better information on objectively measured vision and better delivery of preoperative counselling. Traditional GP referrals contain better medical history, drug information, and details of personal circumstances. Rates of surgery were slightly higher with optometric referrals.
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- 2009
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32. Inadvertent administration of Olbas oil into the eye: a surprisingly frequent presentation.
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Adams MK, Sparrow JM, Jim S, and Tole DM
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- Aged, Humans, Male, Melaleuca, Burns, Chemical etiology, Corneal Injuries, Eye Burns chemically induced, Oils, Volatile adverse effects, Plant Oils adverse effects
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- 2009
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33. Cataract surgery: benchmarks for established and trainee surgeons.
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Sparrow JM
- Subjects
- Cataract Extraction education, Clinical Competence, Humans, Ophthalmology education, Practice Guidelines as Topic, Risk Assessment, Benchmarking, Cataract Extraction standards, Ophthalmology standards
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- 2008
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34. Performance of the 24-2-5 frequency doubling technology screening test: a prospective case study.
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Spry PG, Hussin HM, and Sparrow JM
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- Female, Humans, Male, Middle Aged, Prospective Studies, ROC Curve, Reproducibility of Results, Sensitivity and Specificity, Sensory Thresholds, Time Factors, Vision Tests methods, Visual Fields, Glaucoma diagnosis, Visual Field Tests methods
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Aim: To evaluate the performance of the frequency doubling technology (FDT) 24-2-5 screening test by comparison with the established N-30-5 FDT screening test for detection of glaucoma., Method: A prospective random sample of individuals referred for possible glaucoma were tested with FDT screening tests 24-2-5 and N-30-5 using the Humphrey Matrix perimeter in addition to standard clinical examination relevant to glaucoma detection. Discriminatory power, reliability and test time of these tests were assessed and compared. The case definition for glaucoma was made by patient according to the established clinical diagnosis., Results: Of 63 referred eligible individuals, 53 (84%) were recruited. Sensitivity and specificity for the N-30-5 screening test was 78 and 85% respectively, compared with 83% and 75% for the 24-2-5 with areas under a receiver operator characteristic curve being 0.87 and 0.92. Differences between these indices were not statistically significant. For a specificity of 95%, sensitivity values were 76% and 56% for the 24-2-5 and N-30-5 respectively. Mean (standard deviation) test duration for the FDT 24-2-5 and N-30-5 screening tests were 111 (13) and 39 (10) seconds respectively (p<0.001). A total of 19 subjects (36%) produced unreliable test results in one or both eyes when tested with the 24-2-5 screening test compared with 5 subjects (9%) with the N-30-5 (p<0.0005)., Conclusion: Minimal discriminatory power differences existed between the two screening tests evaluated, with both screening tests exhibiting high discriminatory power for detection of individuals with glaucoma. More individuals produced unreliable results on the 24-2-5 screening, which also took longer to perform.
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- 2007
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35. Pragmatism versus purity: effectiveness of the key informant methodology in a developing rural setting.
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Williams C and Sparrow JM
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- Blindness epidemiology, Blindness prevention & control, Child, Child, Preschool, Female, Health Surveys, Humans, Infant, Infant, Newborn, Male, Blindness diagnosis, Data Collection methods, Developing Countries, Rural Health
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- 2007
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36. Cataract surgical rates: is there overprovision in certain areas?
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Sparrow JM
- Subjects
- Cataract Extraction adverse effects, Cataract Extraction trends, Humans, State Medicine organization & administration, State Medicine trends, United Kingdom, Unnecessary Procedures statistics & numerical data, Cataract Extraction statistics & numerical data
- Published
- 2007
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37. Ultrastructural evaluation of explanted opacified Hydroview (H60M) intraocular lenses.
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Knox Cartwright NE, Mayer EJ, McDonald BM, Skinner A, Salter CJ, Tole DM, Sparrow JM, Dick AD, and Ferguson DJ
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- Calcium analysis, Device Removal, Humans, Microscopy, Electron, Scanning, Phosphorus analysis, Surface Properties, Lenses, Intraocular, Prosthesis Failure
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Aim: To describe the ultrastructural appearance of explanted opacified Hydroview H60M intraocular lenses., Methods: 14 explanted lenses were examined by scanning electron microscopy, and their appearance compared with a non-implanted H60M lens from the same time period. Wavelength-dispersive x ray spectroscopy (WDX) was performed on two opacified lenses., Results: Subsurface deposits were seen in all explanted opacified lenses. These deposits broke only onto the surface of more densely opacified lenses. WDX confirmed that the deposits contained both calcium and phosphorous, consistent with their being calcium apatite., Conclusion: These findings challenge the widely accepted opinion that H60M intraocular lens opacification begins on the surface of the optic.
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- 2007
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38. Monte-Carlo simulation of random clustering of endophthalmitis following cataract surgery.
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Sparrow JM
- Subjects
- Computer Simulation, Disease Outbreaks, Endophthalmitis etiology, Humans, Risk Assessment methods, Space-Time Clustering, Cataract Extraction adverse effects, Endophthalmitis epidemiology, Monte Carlo Method
- Abstract
Background: Endophthalmitis remains a serious and potentially blinding complication of cataract surgery with an overall incidence of approximately 0.14% or one in 700 operations. Despite this knowledge of overall frequency, healthcare providers find themselves confronted with clusters of cases where the appropriate level of response to the cluster is uncertain., Aim: To illustrate, by means of Monte-Carlo simulation models, the likelihood of random clustering of cases arising in units within a healthcare setting resembling the NHS and separately within the practices of individual surgeons., Method: Simulation models were constructed within a programming language in which individual cataract operations were simulated with a one in 700 likelihood of each operation resulting in a 'case of endophthalmitis'. Random clustering of 'cases of endophthalmitis' was observed in the models and 'outbreaks' were noted and tracked for various outbreak definitions., Results: The model outputs are presented graphically as the proportion of 'simulated units' affected by an 'outbreak' in a year and separately as the proportion of surgeons affected for a range of 'outbreak definitions'., Conclusion: These data presentations are easy to use and should facilitate a better understanding of shifts from endemic to epidemic rates of endophthalmitis with appropriate investigation of situations where a remediable common cause may exist.
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- 2007
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39. Risk factors for cataract subtypes waterclefts and retrodots: two case-control studies.
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Durant JS, Frost NA, Trivella M, and Sparrow JM
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- Aged, Alcohol Drinking adverse effects, Analgesics adverse effects, Body Mass Index, Case-Control Studies, Cataract pathology, Estrogen Replacement Therapy adverse effects, Female, Humans, Lipids blood, Male, Middle Aged, Risk Factors, Severity of Illness Index, Sunlight adverse effects, Cataract etiology
- Abstract
Unlabelled: Waterclefts and retrodots are independently associated with visual impairment, yet a review identified no data on risk factors., Purpose: To investigate risk factors for these two human lens cataract subtypes., Method: Two nested case-control studies: The host study comprised 1078 subjects (55 years) attending the Somerset and Avon Eye Study (SAES). In total, 197 watercleft cases (Oxford grade 0.2 in either eye) and 199 retrodot cases (Oxford grade 1.0 in either eye) were individually age/gender matched to controls. Detailed ophthalmic and potential risk factor data were collected, including body mass index (BMI), smoking, alcohol, diabetes, hypertension, analgesics, vitamin supplementation, nutrition, sunlight exposure, dehydration, hormonal (women), blood lipids, glucose, urea, creatinine, uric acid, and vitamin levels., Results: For waterclefts, univariable analysis identified BMI, alcohol intake, vitamin status, sunlight, urea, creatinine, and uric acid as possible risk factors. Multivariable analysis identified two independent associations. Total number of 'any' analgesics in the previous year: adjusted P<0.01 (U-shaped risk profile, unadjusted high vs medium use (=reference) OR 2.39, 95% CI 1.35-4.26 with medium use vs none (=reference) OR 0.43, 95% CI 0.26-0.72); total sunlight: adjusted P=0.03 (unadjusted highest exposure vs lowest (=reference) OR 3.25, 95% CI 1.11-9.50). For retrodots, univariable analysis identified alcohol, HRT, and lipids. Multivariable analysis identified two independent associations. Mean number of alcohol units consumed per month, adjusted P=0.02 and HDL cholesterol levels, adjusted P=0.02 (unadjusted ORs NS both)., Conclusion: This is the first available published information on risk factors for the human cataractous lens features waterclefts and retrodots.
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- 2006
- Full Text
- View/download PDF
40. In vivo measurement of opacified H60M intraocular lenses using Scheimpflug photography.
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Ross AH, Mundasad MV, Neilson SM, Mayer EJ, Sparrow JM, Dick AD, and Tole DM
- Subjects
- Aged, 80 and over, Diagnostic Techniques, Ophthalmological, Female, Humans, Male, Photography methods, Recurrence, Cataract diagnosis, Lenses, Intraocular
- Published
- 2006
- Full Text
- View/download PDF
41. Cataract in older women exposed to hormone replacement.
- Author
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Sparrow JM
- Subjects
- Aged, Cataract epidemiology, Cataract prevention & control, England epidemiology, Female, Humans, Middle Aged, Risk Factors, Cataract etiology, Estrogen Replacement Therapy adverse effects
- Published
- 2006
- Full Text
- View/download PDF
42. British academic ophthalmology in crisis.
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Sparrow JM
- Subjects
- Biomedical Research trends, Humans, United Kingdom, Workforce, Academic Medical Centers, Ophthalmology trends
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- 2006
- Full Text
- View/download PDF
43. Clinical evaluation of frequency doubling technology perimetry using the Humphrey Matrix 24-2 threshold strategy.
- Author
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Spry PG, Hussin HM, and Sparrow JM
- Subjects
- Aged, Aged, 80 and over, Female, Glaucoma physiopathology, Humans, Male, Middle Aged, Ocular Hypertension diagnosis, Ocular Hypertension physiopathology, Predictive Value of Tests, Prospective Studies, Sensitivity and Specificity, Sensory Thresholds, Visual Fields, Glaucoma diagnosis, Visual Field Tests methods
- Abstract
Aims: To evaluate performance of frequency doubling technology (FDT) perimetry using the Humphrey Matrix 24-2 thresholding program in a hospital eye service (HES) glaucoma clinic., Methods: A random sample of individuals referred consecutively to the HES for suspected glaucoma were examined with 24-2 threshold FDT in addition to routine clinical tests. The discriminatory power of FDT and standard automated perimetry (SAP) were assessed using glaucomatous optic nerve head appearance as the reference gold standard., Results: 48 of 62 eligible referred individuals were recruited. Glaucoma prevalence was 31%. Median test duration per eye was 5 minutes 16 seconds for FDT and 5 minutes 9 seconds for SAP. There was no significant difference (p = 0.184) between proportions of individuals with reliable test results (FDT 75%, SAP 63%). Using a clinically appropriate binary criterion for abnormal visual field, sensitivity and specificity levels were 100% and 26% respectively for FDT and 80% and 52% for SAP. Both tests had higher negative than positive predictive values with marginal differences between tests. Criterion free receiver operator characteristic analysis revealed minimal discriminatory power differences., Conclusions: In a HES glaucoma clinic in which new referrals are evaluated, threshold 24-2 FDT testing with the Humphrey Matrix has performance characteristics similar to SAP. These findings suggest threshold testing using the FDT Matrix and SAP is comparable when the 24-2 test pattern is used.
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- 2005
- Full Text
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44. Pilot National Electronic Cataract Surgery Survey: I. Method, descriptive, and process features.
- Author
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Johnston RL, Sparrow JM, Canning CR, Tole D, and Price NC
- Subjects
- Aged, Aged, 80 and over, Cataract ethnology, Cataract Extraction methods, Cataract Extraction standards, Clinical Competence, Databases as Topic organization & administration, Delivery of Health Care standards, Female, Health Services Accessibility standards, Health Services Accessibility statistics & numerical data, Health Services Research methods, Humans, Male, Medical Audit methods, Outcome Assessment, Health Care, Pilot Projects, Prognosis, State Medicine organization & administration, United Kingdom epidemiology, Visual Acuity, Cataract Extraction statistics & numerical data, Delivery of Health Care statistics & numerical data, Medical Records Systems, Computerized organization & administration
- Abstract
Aim: The primary aim of this large pilot survey was to demonstrate the use and benefits of electronic data collection with respect to rapidly monitoring the access, delivery, and outcome of cataract surgery in the NHS and to update benchmark standards for these parameters of care., Method: Eight NHS departments that currently use specialty-specific electronic clinical systems or Electronic Patient Records (EPR) to collect a minimum preoperative, operative, and anaesthetic data set for cataract surgery agreed to pool their data., Results: A total of 162 surgeons from 50 consultant teams and eight NHS Trusts agreed to submit their data on a total of 16,541 operations for age-related cataract. This report describes the age, sex, and ethnic profiles of the patients, waiting time for surgery, ocular copathology causing a reason for a guarded visual prognosis, visual impairment on admission, visual acuity in the operated eye, and the characteristics of the anaesthetic and surgical procedures., Conclusions: This survey has raised the benchmark standards established by the last National Survey in 1997. There has been a near universal switch to day case, phacosurgery under local anaesthesia (all used in > or =99.1% of cases compared with 70, 77, and 86%, respectively in 1997). The visual impairment in the operated eye is lower with 45% having 6 / 12 or better compared with 27% in 1997. Waiting times and visual impairment in the fellow eye have probably improved although data collection for these variables was incomplete. All departments require specialty-specific clinical systems to efficiently collect and analyse these data and this survey proves their potential to form the basis for national electronic surveys in the future.
- Published
- 2005
- Full Text
- View/download PDF
45. Risk factors for progressive visual field loss in primary open angle glaucoma.
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Spry PG, Sparrow JM, Diamond JP, and Harris HS
- Subjects
- Age Factors, Aged, Disease Progression, Epidemiologic Methods, Female, Humans, Male, Sex Factors, Visual Fields, Glaucoma, Open-Angle physiopathology
- Abstract
Purpose: The aim of this study was to evaluate routine ophthalmic data to identify clinically useful risk factors for progressive visual field loss in patients with primary open-angle glaucoma (POAG) already receiving intraocular pressure-lowering treatments., Methods: A retrospective cohort study design was used. Routine ophthalmic data for all subjects were obtained from case records with the knowledge that baseline clinical data had been collected in a standardised manner. Progression was defined according to the AGIS visual field defect scoring system. Variables evaluated as candidate risk factors for progression were assessed by survival analysis. Factors exerting a significant effect on survival were subsequently tested in a Cox proportional hazards model., Results: A cohort of 108 eligible POAG patients was followed over an average of 3.6 years, with an average visual field intertest interval of 8 months. The incidence rate of progressive loss among the cohort was 5.4 cases per 100 person years. Increasing age was found to be independently associated with a small but significantly increased risk of glaucomatous visual field defect progression (hazard ratio 1.07, P=0.022), and a borderline association was also demonstrated with being male (hazard ratio 2.76, P=0.057)., Conclusions: This retrospective investigation has provided preliminary information on factors associated with increased risk of progressive glaucomatous visual field loss that may inform clinical care strategies. Lack of concordance with other studies suggests that further prospective investigations are needed if risk stratification strategies are to be employed in caring for patients with chronic open-angle glaucoma.
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- 2005
- Full Text
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46. The Bristol cataract listing survey: profile of listed patients with visual acuity 6/12 or better.
- Author
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Malik R, Frost NA, Sparrow JM, and Hale L
- Subjects
- Aged, Aged, 80 and over, Attitude to Health, Cataract complications, Cataract physiopathology, Cross-Sectional Studies, Female, Health Status Indicators, Humans, Male, Middle Aged, Patient Selection, Surveys and Questionnaires, Vision Disorders etiology, Vision Disorders psychology, Cataract psychology, Cataract Extraction, Quality of Life, Visual Acuity
- Abstract
Introduction: The aim of this study was to assess the vision-related quality of life (VR-QOL) in patients with good distance Snellen visual acuity (VA) who are listed for cataract surgery., Methods: An observational cross-sectional prospective study of patients listed for cataract surgery. VA and VR-QOL data using the VCMI questionnaire were collected on patients attending preoperative assessment during June 2002., Results: A total of 397 cataract patients were listed during this month. Following exclusions there were 378 eligible individuals, 210 (56%) of whom had a VA of 6/12 or better in the eye scheduled for surgery. Of these, 40% patients had only mild VR-QOL impairment. More than half of the patients with good VA (6/12 or better) in the surgery eye and mild VR-QOL impairment described their vision as poor in this eye. However, most of these patients were not dissatisfied with their overall level of vision., Conclusion: A significant number of patients listed for cataract surgery with VA of 6/12 or better had only mild VR-QOL impairment and were not dissatisfied with their overall level of vision. The decision to list a patient for surgery may have been based on the patient's perception of monocular vision rather than their quality of life.
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- 2005
- Full Text
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47. How should cataracts be measured?
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Sparrow JM and Frost NA
- Subjects
- Humans, Patient Selection, Risk Assessment methods, Cataract diagnosis, Cataract Extraction
- Published
- 2004
- Full Text
- View/download PDF
48. Effect of a patient training video on visual field test reliability.
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Sherafat H, Spry PG, Waldock A, Sparrow JM, and Diamond JP
- Subjects
- Aged, Female, Humans, Male, Middle Aged, Prospective Studies, Reproducibility of Results, Patient Education as Topic methods, Videotape Recording, Vision Tests standards, Visual Fields
- Abstract
Aims: To evaluate the effect of a visual field test educational video on the reliability of the first automated visual field test of new patients., Methods: A prospective, randomised, controlled trial of an educational video on visual field test reliability of patients referred to the hospital eye service for suspected glaucoma was undertaken. Patients were randomised to either watch an educational video or a control group with no video. The video group was shown a 4.5 minute audiovisual presentation to familiarize them with the various aspects of visual field examination with particular emphasis on sources of unreliability. Reliability was determined using standard criteria of fixation loss rate less than 20%, false positive responses less than 33%, and false negative responses less than 33%., Results: 244 patients were recruited; 112 in the video group and 132 in the control group with no significant between group difference in age, sex, and density of field defects. A significant improvement in reliability (p=0.015) was observed in the group exposed to the video with 85 (75.9%) patients having reliable results compared to 81 (61.4%) in the control group. The difference was not significant for the right (first tested) eye with 93 (83.0%) of the visual fields reliable in the video group compared to 106 (80.0%) in the control group (p = 0.583), but was significant for the left (second tested) eye with 97 (86.6 %) of the video group reliable versus 97 (73.5%) of the control group (p = 0.011)., Conclusions: The use of a brief, audiovisual patient information guide on taking the visual field test produced an improvement in patient reliability for individuals tested for the first time. In this trial the use of the video had most of its impact by reducing the number of unreliable fields from the second tested eye.
- Published
- 2003
- Full Text
- View/download PDF
49. National audit of the outcome of primary surgery for rhegmatogenous retinal detachment. I. Sample and methods.
- Author
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Thompson JA, Snead MP, Billington BM, Barrie T, Thompson JR, and Sparrow JM
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Cross-Sectional Studies, Health Care Surveys methods, Humans, Middle Aged, Reproducibility of Results, Selection Bias, Surveys and Questionnaires, Treatment Outcome, United Kingdom, Medical Audit methods, Retinal Detachment surgery
- Abstract
Purpose: This national study was designed to audit anatomical outcome and complications relating to primary surgery for rhegmatogenous retinal detachments. This paper presents survey methods, characteristics of participating consultants and the demographic and clinical characteristics of the patient sample., Methods: Two surveys were undertaken. The first identified consultants who at the time performed retinal detachment surgery in the National Health Service. These surgeons formed the sampling frame for a nationwide cross-sectional clinical study that audited the outcomes of primary surgery for rhegmatogenous retinal detachments. Consultants selected patients according to the study eligibility criteria and data were collected by self-administered postal questionnaires. A validation exercise was carried out to examine selection bias and reporting accuracy., Results: Only 256/671 (38%) of UK consultants, who responded to the first survey, indicated that they performed retinal detachment surgery on NHS patients. Annual activity varied between 0 and 400 primary procedures for rhegmatogenous retinal detachments. Seven hundred and sixty-eight eligible patients from 167 consultants were recruited for the clinical study. Twenty per cent of patients had a single retinal break with less than one quadrant of associated detachment and 45% had single or multiple breaks within the same quadrant and/or less than two quadrants of associated retinal detachment. Over 50% patients had single or multiple horseshoe tears. Validation studies suggested that there was no significant bias from the selection of patients or inaccuracy in reporting outcomes., Conclusions: This large unselected group of primary rhegmatogenous retinal detachments provides a representative sample for considering variations in re-attachment rates.
- Published
- 2002
- Full Text
- View/download PDF
50. National audit of the outcome of primary surgery for rhegmatogenous retinal detachment. II. Clinical outcomes.
- Author
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Thompson JA, Snead MP, Billington BM, Barrie T, Thompson JR, and Sparrow JM
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Clinical Competence, Cross-Sectional Studies, Follow-Up Studies, Health Care Surveys, Humans, Medical Staff, Hospital standards, Middle Aged, Multivariate Analysis, Postoperative Complications, Reproducibility of Results, Severity of Illness Index, Specialization, Surveys and Questionnaires, Treatment Outcome, United Kingdom, Medical Audit, Retinal Detachment surgery
- Abstract
Purpose: This national study was designed to audit anatomical outcome and complications relating to primary surgery for rhegmatogenous retinal detachments. This paper presents success and complication rates, and examines variations in outcome., Methods: Sampling and recruitment details of this nationwide cross-sectional survey of 768 patients of 167 consultant ophthalmologists having their first operation for rhegmatogenous retinal detachment have been described. The main clinical outcomes detailed here are anatomical reattachment at 3 months after surgery and complications related to surgery. Consultants with a declared special interest in retinal surgery and able to perform pars plana vitrectomy were designated specialists for the analyses., Results: Overall reattachment rate with a single procedure was 77% (95% CI 73.9-80.2). There were significant differences in reattachment rates between specialists and non-specialists. Without allowing for case-mix, specialists had a reattachment rate of 82% (95% CI 77.9-85.7) with a single procedure and non-specialists 71% (95% CI 65.9-76.0). Allowing for case-mix, there was a significant difference between specialists and non-specialists for grade 2 detachments of 87% and 70% respectively (P < 0.0001). Analysing detachments by break type, the largest difference between specialists and non-specialists was observed for retinal detachments secondary to horseshoe tears, 80% and 68% respectively (P < 0.003). Specialists met the standards set for primary reattachment rates, while non-specialists did not. Over a third of patients had at least one complication reported at some point during the audit period., Conclusions: Significant differences were seen in reattachment rates between specialists and non-specialists, overall and for specific subgroups of patients. This study provides relevant, robust and valid standards to enable all surgeons to audit their own surgical outcomes for primary retinal detachment repair in rhegmatogenous retinal detachments, identify common categories of failure and aim to improve results.
- Published
- 2002
- Full Text
- View/download PDF
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