Search

Summary Wearable optoelectronic devices can interface with the skin for applications in continuous health monitoring and light-based therapy. Measurement of the thermal effect of light on skin is often critical to track physiological parameters and control light delivery. However, accurate measurement of light-induced thermal effects is challenging because conventional sensors cannot be placed on the skin without obstructing light delivery. Here, we report a wearable optoelectronic patch integrated with a transparent nanowire sensor that provides light delivery and thermal monitoring at the same location. We achieve fabrication of a transparent silver nanowire network with >92% optical transmission that provides thermoresistive sensing of skin temperature. By integrating the sensor in a wireless optoelectronic patch, we demonstrate closed-loop regulation of light delivery as well as thermal characterization of blood flow. This light delivery and thermal monitoring approach may open opportunities for wearable devices in light-based diagnostics and therapies., Graphical abstract, Highlights • A wireless optoelectronic patch measures photothermal effects on the skin • A transparent nanowire sensor enables co-located light delivery and thermal monitoring • Experiments demonstrate closed-loop thermal regulation and blood flow monitoring, Health technology; Optoelectronics; Bioelectronics

Description, A wireless sensor based on bioresponsive DNA hydrogel provides smartphone-based detection of wound infection., The confluence of wireless technology and biosensors offers the possibility to detect and manage medical conditions outside of clinical settings. Wound infections represent a major clinical challenge in which timely detection is critical for effective interventions, but this is currently hindered by the lack of a monitoring technology that can interface with wounds, detect pathogenic bacteria, and wirelessly transmit data. Here, we report a flexible, wireless, and battery-free sensor that provides smartphone-based detection of wound infection using a bacteria-responsive DNA hydrogel. The engineered DNA hydrogels respond selectively to deoxyribonucleases associated with pathogenic bacteria through tunable dielectric changes, which can be wirelessly detected using near-field communication. In a mouse acute wound model, we demonstrate that the wireless sensor can detect physiologically relevant amounts of Staphylococcus aureus even before visible manifestation of infection. These results demonstrate strategies for continuous infection monitoring, which may facilitate improved management of surgical or chronic wounds.

Networks of sensors placed on the skin can provide continuous measurement of human physiological signals for applications in clinical diagnostics, athletics and human-machine interfaces. Wireless and battery-free sensors are particularly desirable for reliable long-term monitoring, but current approaches for achieving this mode of operation rely on near-field technologies that require close proximity (at most a few centimetres) between each sensor and a wireless readout device. Here, we report near-field-enabled clothing capable of establishing wireless power and data connectivity between multiple distant points around the body to create a network of battery-free sensors interconnected by proximity to functional textile patterns. Using computer-controlled embroidery of conductive threads, we integrate clothing with near-field-responsive patterns that are completely fabric-based and free of fragile silicon components. We demonstrate the utility of the networked system for real-time, multi-node measurement of spinal posture as well as continuous sensing of temperature and gait during exercise., Though wireless near-field communication (NFC) technologies that connect wearable sensors for health monitoring have been reported, the short range of NFC readers limits sensor functionality. Here, the authors report a wireless and battery-free body sensor network with near-field-enabled clothing.