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3. Transformation of diffuse large B-cell lymphoma to lymphoblastic lymphoma

Author

Kushwaha, Pritika, Singh, Meeta, Mallya, Varuna, Jain, Shyama, Aggarwal, Sunita, and Singh, Kishore

Subjects
Non-Hodgkin's lymphomas -- Case studies -- Development and progression -- Diagnosis, Health
Abstract

Byline: Pritika. Kushwaha, Meeta. Singh, Varuna. Mallya, Shyama. Jain, Sunita. Aggarwal, Kishore. Singh Transformations in diffuse large B-cell lymphoma (DLBCL) are extremely rare. Here, we are presenting a very rare [...]

Published
2022

4. Low-grade appendiceal mucinous neoplasms: Histomorphological spectrum in a tertiary care hospital.

Author

Ahuja, Manisha, Mandal, Shramana, Mallya, Varuna, Singh, Meeta, Khurana, Nita, and Lal, Pawanindra

Subjects
APPENDIX (Anatomy), SYMPTOMS, MUCINS, TERTIARY care, MEDICAL personnel, APPENDICITIS
Abstract

Background: Low-grade appendiceal mucinous neoplasms (LAMNs) are benign non-invasive epithelial proliferations of the appendix. These usually present clinically as mucoceles and these rarely exceed 2 cm in diameter. Lesions confined to the lumen are labelled as LAMN; however those in which mucin spreads outside the peritoneum are labeled as pseudomyxoma peritonei (PMP). Aims and Objective: A retrospective study was conducted over a period of three years and all cases of appendectomies were studied. Twelve cases of LAMN were identified, which is a diagnostic dilemma for the pathologists and clinicians. Results: LAMN was identified based on the histopathological features. Out of the 12 cases, 9 were classified as LAMN and 3 as appendiceal neoplasm with PMP. There was villous or flat proliferation of epithelial lining, loss lymphoid aggregates, and dissecting mucin within muscularis. Conclusion: LAMNs are rare neoplasms of the appendix, with clinical presentation similar to acute appendicitis. Mucinous collections within the appendiceal wall should be extensively searched for mucosal changes and, if found, should prompt a careful search for pushing invasion of LAMNs. A thorough and vigilant gross examination can be of great help. Appendicectomy is the treatment of benign and grossly intact mucinous neoplasm. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Salivary Gland NHL - An FNAC-Flow Cytometry Study.

Author

Gautam, Rashmi, Singh, Meeta, Nain, Gunjan, Mallya, Varuna, Kushwaha, Pritika, Singh, Sarika, Tomar, Reena, Meher, Ravi, and Kumar, Jyoti

Subjects
*CYTOLOGY, *PHYSICAL diagnosis, *NON-Hodgkin's lymphoma, *XEROSTOMIA, *IMMUNOHISTOCHEMISTRY, *CANCER chemotherapy, *NEEDLE biopsy, *X-rays, *SALIVARY glands, *PAROTID glands
Abstract

The article presents two case studies of salivary gland non-Hodgkin lymphomas (NHLs) diagnosed using fine needle aspiration cytology (FNAC) and flow cytometry, with confirmation from histopathologic examination. It highlights the diagnostic process, detailing the clinical presentation, cytological and flow cytometric findings, and the subsequent histopathologic confirmation in both cases.

Published
2024
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9. Fine needle aspiration cytology of primary thyroid non-hodgkins lymphoma: Experience from a tertiary care center of North India

Author

Singh, Meeta, Nain, Gunjan, Jain, Shyama, Singh, Sarika, and Malhotra, Vikas

Subjects
Biopsy, Needle -- Usage -- Statistics, Cytodiagnosis -- Usage -- Statistics, Non-Hodgkin's lymphomas -- Diagnosis -- Statistics, Thyroid cancer -- Diagnosis -- Statistics, Health
Abstract

Byline: Meeta. Singh, Gunjan. Nain, Shyama. Jain, Sarika. Singh, Vikas. Malhotra Presentation: Twelve cases of Primary Thyroid Non-Hodgkin's Lymphoma (PT-NHL) were retrieved from the records suspected or diagnosed as NHL [...]

Published
2022

10. Congenital pulmonary airway malformation - A histomorphological spectrum of 15 cases: A 5-year study from a tertiary care center

Author

Gupta, Kanika, Singh, Vishal, Mandal, Shramana, Mallya, Varuna, Singh, Meeta, Khurana, Nita, and Sarin, Y.

Subjects
Medical research, Medicine, Experimental, Genetic disorders, Lung diseases, Hydrops fetalis, Health
Abstract

Byline: Kanika. Gupta, Vishal. Singh, Shramana. Mandal, Varuna. Mallya, Meeta. Singh, Nita. Khurana, Y. Sarin Objective: Congenital pulmonary airway malformation (CPAM) is a rare developmental lung disease. The aim of [...]

Published
2021

11. Acinic cell carcinoma of the parotid gland with neuroendocrine differentiation

Author

Rath, Ashutosh, Tomar, Reena, Agarwal, Radhika, Singh, Meeta, Jain, Shyama, Khurana, Nita, and Rathore, Praveen

Subjects
Salivary gland tumors -- Case studies, Health
Abstract

Byline: Ashutosh. Rath, Reena. Tomar, Radhika. Agarwal, Meeta. Singh, Shyama. Jain, Nita. Khurana, Praveen. Rathore Acinic cell carcinoma (ACC) is a malignant salivary gland tumor characterized by tumor cells displaying [...]

Published
2021

15. Radiation-induced leiomyosarcoma of oral cavity: Two cases with a review of literature

Author

Sagar, Nishant, Singh, Meeta, Goyal, Neelakshi, Khurana, Nita, Singh, Kishore, and Meher, Ravi

Subjects
Mouth tumors -- Case studies -- Diagnosis, Squamous cell carcinoma -- Case studies -- Care and treatment, Leiomyosarcoma -- Case studies -- Diagnosis, Radiotherapy -- Case studies -- Complications and side effects, Health
Abstract

Byline: Nishant. Sagar, Meeta. Singh, Neelakshi. Goyal, Nita. Khurana, Kishore. Singh, Ravi. Meher Radiation-induced sarcoma is a rare entity, with leiomyosarcoma (LMS) in the oral cavity post radiation being extremely [...]

Published
2020

18. Clinicopathological correlation of tumor-stroma ratio and inflammatory cell infiltrate with tumor grade and lymph node metastasis in squamous cell carcinoma of buccal mucosa and tongue in 41 cases with review of literature

Author

Rani, Poonam, Gupta, Amita, Mehrol, Chetna, Singh, Meeta, Khurana, Nita, and Passey, J.

Subjects
Cervical cancer -- Development and progression, Squamous cell carcinoma -- Development and progression, Cancer metastasis -- Development and progression, Health
Abstract

Byline: Poonam. Rani, Amita. Gupta, Chetna. Mehrol, Meeta. Singh, Nita. Khurana, J. Passey Introduction: Several studies regarding tumor-stroma ratio (TSR) in colorectal, esophageal, breast, endometrial, and cervical carcinomas have been [...]

Published
2020

19. Sleep and athletes

Author

Singh, Meeta, Bird, Stephen P., Charest, Jonathan, Workings, Michael, Singh, Meeta, Bird, Stephen P., Charest, Jonathan, and Workings, Michael

Abstract

Sleep is recognized as an essential component to optimize health and human performance, and as such the topic is of increasing interest to athletes. Yet, the sleep of athletes is affected by multiple sports-specific and societal factors. Hence the recent emergence of the important role of sleep science in athlete health and performance. This review focuses on the fundamentals of sleep physiology and elaborates on the affects sleep has on athlete health and performance. Despite sports practitioners recognizing the importance of sleep on health and performance, findings report that insufficient sleep and poor sleep quality are prevalent among athletic populations. This paper will describe sleep in athletes, define sleep characteristics, discuss the impact of sleep restriction following travel and competition, and strategies to mitigate sleep difficulties. Sleep is arguably the most undervalued pillar of health and performance.

Published
2022

20. How Sleep Affects Recovery and Performance in Basketball: A Systematic Review

Author

Educación física y deportiva, Gorputz eta Kirol Hezkuntza, Ochoa Lácar, Javier, Singh, Meeta, Bird, Stephen P., Charest, Jonathan, Huygue, Thomas, Calleja González, Julio María, Educación física y deportiva, Gorputz eta Kirol Hezkuntza, Ochoa Lácar, Javier, Singh, Meeta, Bird, Stephen P., Charest, Jonathan, Huygue, Thomas, and Calleja González, Julio María

Abstract

Background: Sleep is considered an essential component related to physiological and psychological recovery in athletes and particularly in basketball, given the impact of condensed travel and game schedules on player health and performance. Objective: The aim of this systematic review is to examine studies published to date on sleep and basketball performance. Methodology: All scientific articles that reported a relationship between sleep and its possible impact on performance in basketball are included. The research processes followed the PRISMA criteria, and the relevant articles were extracted (PubMed, WOS, Scopus) as of December 31, 2021. Results: Twenty-eight articles were selected for inclusion and data extraction, with 27 demonstrating that sleep is a vital component in the recovery of basketball players and their corresponding on-court performance. Three central themes that we identified: (1) the quality and extension of sleep (the better quality and more extension of sleep, better performance and lower probability of injury); (2) influence of the players circadian rhythm (travel and game scheduling do not currently facilitate or take this into account); and (3) higher training loads and/or increased stress may jeopardize a subsequent good night’s sleep, which should be taken into account when scheduling practices and workouts. Conclusion: The current systematic review regarding sleep and basketball performance and highlights that there is a strong relationship between both variables. Collectively, the evidence supports the critical influence of sleep on player recovery and basketball performance and risk for injury.

Published
2022

27. The Recovery Umbrella in the World of Elite Sport: Do Not Forget the Coaching and Performance Staff

Author

Calleja-González, Julio, primary, Bird, Stephen, additional, Huyghe, Thomas, additional, Jukic, Igor, additional, Cuzzolin, Francesco, additional, Cos, Francesc, additional, Marqués-Jiménez, Diego, additional, Milanovic, Luka, additional, Sampaio, Jaime, additional, López-Laval, Isaac, additional, Ostojic, Sergej, additional, Jones, Margaret, additional, Alcaraz, Pedro, additional, Schelling, Xavi, additional, Delextrat, Anne, additional, Singh, Meeta, additional, Charest, Jonathan, additional, Freitas, Tomás, additional, Torres Ronda, Lorena, additional, Petway, Adam, additional, Medina, Daniel, additional, Tramullas, Antonio, additional, Mielgo-Ayuso, Juan, additional, Terrados, Nicolas, additional, and McLellan, Chris, additional

Published
2021
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31. Cytological Diagnosis of Malignant Mesothelioma: A Case Series.

Author

Dahiya, Sakshi, Singh, Meeta, Jain, Shyama, Khuraijam, Bembem, Suroya, Naman, and Mandal, Shramana

Subjects
*MESOTHELIOMA, *IMMUNOHISTOCHEMISTRY, *RETROSPECTIVE studies, *CASE studies, *CYTOLOGY, *TUMOR markers, *SENSITIVITY & specificity (Statistics), *SYMPTOMS
Abstract

Background: Mesotheliomas are neoplasms of the serosal lining of the body cavities. Diagnosis requires a multimodal approach of clinical findings, cytology, and histopathology with immunohistochemistry (IHC). The published sensitivity of cytology for diagnosing mesothelioma ranges from 30% to 75%. Aim and Objectives: This study aimed to calculate the incidence of malignant mesothelioma (MM) at our institute and to study the cytological features of MM. Materials and Methods: A retrospective study of pleural, peritoneal, and pericardial fluids submitted at our institute was done. The duration of the study was 8 years (2011--2019). Apart from examining Giemsa smears, a panel of immunocytochemical (ICC) and cell block immunohistochemical (IHC) markers was applied to achieve the diagnosis. These included calretinin, mesothelin, CK5/6, Hector Battifora mesothelial cell antibody (HBME), WT1, MOC31, CK7 and CK20. Histopathological correlation was done wherever possible. Result: In the present study, we compiled four cases of MM over 8 years diagnosed on serous effusion cytology and confirmed by immunocytochemistry (ICC)/cell block immunohistochemistry (IHC)/biopsy. This indicates a rare incidence of MM. The Cytological features of MM were studied. Conclusion: The diagnosis of MM is difficult, especially cytologically. It was found to be a rare entity in the malignant cases diagnosed on effusion cytology. [ABSTRACT FROM AUTHOR]

Published
2022
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44. Evaluation of use of RPMI medium to preserve cell morphology for pleural/peritoneal fluid cytology.

Author

Rani, Usha, Singh, Meeta, Saith, Armaan, Jain, Shayama, Aggarwal, Anurag, and Aggarwal, Sunita

Subjects
*BODY fluid analysis, *HOST-bacteria relationships, *PLEURAL effusions, *REFRIGERATION & refrigerating machinery, *TEMPERATURE, *CULTURE media (Biology), *ASCITES, *CYTOLOGY
Abstract

Introduction: Cytologic evaluation is the best way to detect the presence of malignancy in body cavity fluids. Roswell Park Memorial Institute (RPMI) medium or RPMI 1640 is used in cell culture, tissue culture, and also to improve the cellularity and morphology of CSF cytology specimens. Objectives: To determine whether RPMI medium can be used to preserve cell morphology in pleural/peritoneal effusion samples. Method and Material: The study was conducted on 30 pleural/peritoneal fluid samples received routinely during 2 months for diagnostic purposes in our department. The samples were divided into four parts. One-fourth of the sample was directly refrigerated and the other fourth was at room temperature. In the other two parts, an equal volume of RPMI media was added, and one was kept at room temperature and the other refrigerated. These cytospin-prepared Giemsa-stained smears were examined for cell morphology, cellularity, and occurrence of bacterial colonies at 24 h, 48 h, 72 h, and 1 week, respectively. Result: Refrigerated RPMI medium is the best preservative for pleural/peritoneal samples; however, samples with RPMI at room temperature were equivalent/even worse than the simple refrigerated sample. [ABSTRACT FROM AUTHOR]

Published
2022
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45. USG guided fine needle aspiration cytology along with immunocytochemistry to diagnose primary malignant mixed mullerian tumors: A three-year study from a tertiary care center.

Author

Agarwal, Radhika, Singh, Meeta, Goswami, Sneha, Mandal, Shramana, Verma, Devender, Khurana, Nita, Jain, Shyama, and Verma, Nidhi

Subjects
*PROTEINS, *ULTRASONIC imaging, *CANCER cells, *OVARIAN tumors, *BIOPSY, *IMMUNOHISTOCHEMISTRY, *UTERINE tumors, *TERTIARY care, *RETROSPECTIVE studies, *CYTOSKELETAL proteins, *PAP test, *CYTOLOGY, *ADNEXAL diseases, *SENSITIVITY & specificity (Statistics), *NEEDLE biopsy, *FEMALE reproductive organ tumors
Abstract

Aims and Objectives: To study the diagnostic utility of fine-needle aspiration cytology (FNAC) and immunocytochemistry in diagnosing primary malignant mixed Mullerian tumors (MMMT). Materials and Methods: A 3-year retrospective study carried out in a tertiary care hospital, which included all the gynecological patients who underwent USG-guided FNAC of their abdominopelvic masses. Observations and Results: Out of the 324 total cases, 05 (1.5%) were reported as primary malignant mixed Mullerian tumors. Out of these 05 cases, 03 were ovarian, 01 was uterine, and 01 involved both uterus and one-sided adnexa. The FNA smears from the masses revealed cytomorphological features of a biphasic neoplasm with elongated pleomorphic spindle cells and dispersed, focal attempted acinar pattern, thus indicating the possibility of MMMT. Immunocytochemistry was further carried out which showed both vimentin and cytokeratin positivity. The diagnosis was confirmed on subsequent biopsy and immunohistochemistry (without any histopathological-cytological discrepancy). Conclusion: Though the literature is replete in establishing a histo-pathological diagnosis of MMMT, the diagnosis on USG-guided FNAC has been rarely described. Emphasis should be made on the careful examination of small sarcomatous elements in smears. Utilization of cell block and immunocytochemistry with histopathological correlation should be done to avoid misdiagnosis. [ABSTRACT FROM AUTHOR]

Published
2022
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